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searching for AKT1 39 found (382 total)

alternate case: aKT1

Periplakin (1,064 words) [view diff] exact match in snippet view article find links to article

the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling

AKT1S1 (747 words) [view diff] exact match in snippet view article find links to article

Proline-rich AKT1 substrate 1 (PRAS) is a protein that in humans is encoded by the AKT1S1 gene. GRCh38: Ensembl release 89: ENSG00000204673 – Ensembl,

GAB2 (3,189 words) [view diff] no match in snippet view article find links to article

GRB2-associated-binding protein 2 also known as GAB2 is a protein that in humans is encoded by the GAB2 gene. GAB2 is a docking protein with a conserved

PI3K/AKT/mTOR pathway (4,322 words) [view diff] case mismatch in snippet view article find links to article

isozymes, Akt1, Akt2 and Akt3. Small-molecule inhibitors of Akt1 could be especially useful to target tumors with a high prevalence of Akt1 E17K activating

PANTHER (2,612 words) [view diff] exact match in snippet view article find links to article

subfamily "PTHR24352:SF30" for AKT1. GO molecular function: This tell you what are the functions of your query gene; e.g. AKT1 has protein kinase activity

Akt/PKB signaling pathway (4,116 words) [view diff] case mismatch in snippet view article find links to article

sclerosis complex 2 (TSC2) - Akt1 destabilises the Rho GTPase, inhibits F-actin assembly and reduces cell migration Palladin - Akt1 phosphorylates the actin-binding

Homeobox (4,469 words) [view diff] case mismatch in snippet view article find links to article

COX-2, respectively. HoxA5 also upregulates the tumor suppressor p53 and Akt1 by downregulation of PTEN. Suppression of HoxA5 has been shown to attenuate

Jacques Neefjes (1,106 words) [view diff] exact match in snippet view article find links to article

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1. Kuijl C, Savage ND, Marsman M, Tuin AW, Janssen L, Egan DA, Ketema M, Van

TRHDE (347 words) [view diff] exact match in snippet view article find links to article

Dicker A, Mills GB, Hung MC, Lev D (January 2011). "Vimentin is a novel AKT1 target mediating motility and invasion". Oncogene. 30 (4): 457–70. doi:10

Protein phosphatase (2,519 words) [view diff] case mismatch in snippet view article find links to article

Zhang; Y Liu; D W-C Li (26 February 2010). "Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and

Vijayalakshmi Ravindranath (800 words) [view diff] case mismatch in snippet view article find links to article

Durgadoss, Lalitha; Ravindranath, Vijayalakshmi (2014). "Critical cysteines in Akt1 regulate its activity and proteasomal degradation: Implications for neurodegenerative

SYAP1 (408 words) [view diff] case mismatch in snippet view article find links to article

Reddy SA (January 2013). "BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation"

Capivasertib (608 words) [view diff] exact match in snippet view article find links to article

2-negative locally advanced or metastatic breast cancer with one or more PIK3CA/AKT1/PTEN-alterations, as detected by an FDA-approved test, following progression

Ketan J. Patel (1,503 words) [view diff] exact match in snippet view article find links to article

E. (2007). "A transforming mutation in the pleckstrin homology domain of AKT1 in cancer". Nature. 448 (7152): 439–44. Bibcode:2007Natur.448..439C. doi:10

Gene nomenclature (4,143 words) [view diff] exact match in snippet view article find links to article

symbol for the gene v-akt murine thymoma viral oncogene homolog 1, which is AKT1, cannot be said to be an acronym for the name, and neither can any of its

Peroxisome proliferator-activated receptor delta (2,093 words) [view diff] case mismatch in snippet view article find links to article

"Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway". Molecular Cell. 10 (4): 721–733. doi:10.1016/S1097-2765(02)00646-9

Follicular dendritic cell sarcoma (2,551 words) [view diff] case mismatch in snippet view article find links to article

Chen, William S; Hay, Nissim; Bornstein, Paul; Byzova, Tatiana V (2005). "Akt1 regulates pathological angiogenesis, vascular maturation and permeability

BSD domain (299 words) [view diff] case mismatch in snippet view article find links to article

Reddy SA (January 2013). "BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation"

Neuregulin 3 (2,559 words) [view diff] exact match in snippet view article find links to article

brain, promotes the survival of oligodendrocyte with the aid of ERBB4/PI3K/AKT1 pathway and also partakes in NRG3-ERBB4 signaling in neurodevelopment and

SKP2 (4,001 words) [view diff] case mismatch in snippet view article find links to article

Inuzuka H, Tseng A, Chin RY, Toker A, Wei W (April 2009). "Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2

MAPK8IP3 (1,260 words) [view diff] case mismatch in snippet view article find links to article

"Cross-talk between JIP3 and JIP1 during glucose deprivation: SEK1-JNK2 and Akt1 act as mediators". J. Biol. Chem. 280 (29): 26845–55. doi:10.1074/jbc.M502318200

TCL1 MTCP1 protein domain (298 words) [view diff] exact match in snippet view article find links to article

membrane potential. This protein exists as a homodimer. It interacts with AKT1, AKT2 and AKT3 via the PH protein domain. It interacts with PNPT1; the interaction

Claes Bang (2,054 words) [view diff] exact match in snippet view article find links to article

L'histoire du soldat The Devil/Narrator Copenhagen Phil 2015 Danske Permafrost AKT1 Danmarks Lydteater Live in the Dome of Visions, Copenhagen The Evil Erik

Fibroblast growth factor receptor 1 (5,001 words) [view diff] exact match in snippet view article find links to article

associated with hypomethylation of a 5' CpG island and abnormal expression of the AKT1, NOG, and BMP4 genes". Genes, Chromosomes & Cancer. 46 (11): 1028–1038. doi:10

MUL1 (1,339 words) [view diff] exact match in snippet view article find links to article

directly transfer the ubiquitin to targeted substrates. Can ubiquitinate AKT1 preferentially at 'Lys-284' involving 'Lys-48'-linked polyubiquitination

Scoring functions for docking (2,545 words) [view diff] case mismatch in snippet view article find links to article

improve the accuracy of molecular docking: toward the discovery of novel Akt1 inhibitors". European Journal of Medicinal Chemistry. 75: 11–20. doi:10.1016/j

TRIM14 (1,278 words) [view diff] case mismatch in snippet view article find links to article

(nf-kb1, rela, nf-kb2, relb), grb2, grb3-3, traf3ip2, junB, c-myb, pu.1, akt1, tyk2, erk2, and mek2. In the same cells, the stable expression of TRIM14

Anaplastic large-cell lymphoma (5,218 words) [view diff] exact match in snippet view article find links to article

PMID 24102046. NPM1 nucleophosmin 1 [Homo sapiens (human)] – Gene – NCBI AKT1 AKT serine/threonine kinase 1 [Homo sapiens (human)] – Gene – NCBI Kuravi

Let-7 microRNA precursor (8,297 words) [view diff] case mismatch in snippet view article find links to article

Doxaki C, Schworer S, Zacharioudaki V, et al. (August 2009). "The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs"

Potassium uptake permease (1,037 words) [view diff] exact match in snippet view article find links to article

MH (June 2010). "High-affinity K(+) transport in Arabidopsis: AtHAK5 and AKT1 are vital for seedling establishment and postgermination growth under low-potassium

Inflammatory myofibroblastic tumour (3,914 words) [view diff] exact match in snippet view article find links to article

Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". "AKT1 AKT serine/threonine kinase 1 [Homo sapiens (human)] - Gene - NCBI". www

Facial infiltrating lipomatosis (781 words) [view diff] exact match in snippet view article find links to article

The current drug treatment options are either a mTOR inhibitor, a pan AKT (AKT1-2-3) inhibitor or a PIK3CA inhibitor. The mTOR inhibitor is an off-label

C11orf49 (1,337 words) [view diff] exact match in snippet view article find links to article

Position AA Kinase 310 Serine AGC/Akt 48 Threonine AGC/Akt/AKT1 66 Serine AGC/Akt 318 Serine AGC/Akt

MiR-155 (10,421 words) [view diff] case mismatch in snippet view article find links to article

Zacharioudaki V, Margioris AN, Tsichlis PN, Tsatsanis C (Aug 2009). "The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs"

Tramp species (2,543 words) [view diff] case mismatch in snippet view article find links to article

venom against lipopolysaccharides through antioxidant and upregulation of Akt1 signaling in rats". Lipids in Health and Disease. 11 (1): 93. doi:10.1186/1476-511x-11-93

Sandro Santagata (1,492 words) [view diff] exact match in snippet view article find links to article

Dias-Santagata, Dora (2016-05-01). "Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma". Neuro-Oncology. 18 (5): 649–655. doi:10

DIRAS1 (1,007 words) [view diff] exact match in snippet view article find links to article

Re-expresison of the DIRAS1 gene induces and regulates autophagy by inhibiting the AKT1-MTOR and RAS-MAPK signaling pathway and modulating nuclear localization of

Mouse models of breast cancer metastasis (5,955 words) [view diff] case mismatch in snippet view article find links to article

including: PI3K/Akt signalling in metastasis can be demonstrated in MMTV-PyMT; Akt1−/− mice. Chemoattractive paracrine loop of colony-stimulating factor-1 (CSF-1)

Alfred G. Redfield (3,673 words) [view diff] case mismatch in snippet view article find links to article

"Cytotoxic amphiphiles and phosphoinositides bind to two discrete sites on the Akt1 PH domain". Biochemistry. 53 (35): 462–472. doi:10.1021/bi401720v. PMID 24383815