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searching for Animal models of depression 25 found (44 total)

alternate case: animal models of depression

MRK-016 (166 words) [view diff] exact match in snippet view article find links to article

found to produce rapid, ketamine-like antidepressant effects in animal models of depression. GABAA receptor negative allosteric modulator GABAA receptor

Perforant path (649 words) [view diff] exact match in snippet view article find links to article

temporoammonic pathway has also been implicated in stress-based animal models of depression. It may also play a role in temporal lobe seizures. In rats,

7-Chlorokynurenic acid (555 words) [view diff] exact match in snippet view article find links to article

receptor. It produces ketamine-like rapid antidepressant effects in animal models of depression. However, 7-CKA is unable to cross the blood-brain-barrier, and

L-655,708 (816 words) [view diff] exact match in snippet view article find links to article

MRK-016, produced rapid, ketamine-like antidepressant effects in animal models of depression. GABAA receptor negative allosteric modulator GABAA receptor

Pimozide (994 words) [view diff] case mismatch in snippet view article find links to article

"Anti-depressant like Effect of Pimozide in Acute and Chronic Animal Models of Depression". Indian Journal of Pharmaceutical Education and Research. 45

Selank (670 words) [view diff] exact match in snippet view article find links to article

Selank has been found to produce antidepressant-like effects in animal models of depression and anhedonia. In clinical trials, the drug has shown to provide

N-Acetylserotonin (1,142 words) [view diff] exact match in snippet view article find links to article

significantly greater immobility times versus control mice in animal models of depression. These data support a potential role for NAS in mood regulation

Anxiogenic (1,626 words) [view diff] exact match in snippet view article find links to article

Sánchez, C.; Meier, E. (1997). "Behavioral profiles of SSRIs in animal models of depression, anxiety and aggression". Psychopharmacology. 129 (3): 197–205

JDTic (1,468 words) [view diff] exact match in snippet view article find links to article

addiction to cocaine and morphine. JDTic shows robust activity in animal models of depression, anxiety, stress-induced cocaine relapse, and nicotine withdrawal

Histone deacetylase inhibitor (2,973 words) [view diff] exact match in snippet view article find links to article

well as sodium butyrate both increased expression of BDNF in animal models of depression. One study which traced GDNF levels in the ventral striatum found

Metabotropic glutamate receptor 2 (2,647 words) [view diff] exact match in snippet view article find links to article

of a group II metabotropic glutamate receptor antagonist in animal models of depression". Behavioural Brain Research. 238: 48–52. doi:10.1016/j.bbr.2012

Aticaprant (2,211 words) [view diff] exact match in snippet view article find links to article

consistent with modest MOR antagonism at the 10 mg dose. In animal models of depression, aticaprant has been found to have potent synergistic efficacy

Buprenorphine/samidorphan (1,992 words) [view diff] exact match in snippet view article find links to article

cocaine). Accordingly, KOR antagonists show robust efficacy in animal models of depression, anxiety, anhedonia, drug addiction, and other stress-related

Immediate early gene (1,965 words) [view diff] exact match in snippet view article find links to article

process involving the GADD45G protein. IEGs are used as markers in animal models of depression. Affected mice have altered levels of Arc,affecting synaptic

Melanocortin 4 receptor (3,164 words) [view diff] exact match in snippet view article find links to article

produce pronounced antidepressant- and anxiolytic-like effects in animal models of depression and anxiety. And agonists of the MC4 receptor such as melanotan

Bromantane (3,192 words) [view diff] exact match in snippet view article find links to article

cytokines IL-6, IL-17 and IL-4 and to normalize behavior in animal models of depression, and may possess clinical efficacy as an antidepressant. It has

Arketamine (1,236 words) [view diff] exact match in snippet view article find links to article

shows greater and longer-lasting rapid antidepressant effects in animal models of depression relative to esketamine. It has been suggested that this may be

Sibutramine (3,518 words) [view diff] exact match in snippet view article find links to article

antidepressants, and it has demonstrated antidepressant effects in animal models of depression. It was approved by the U.S. Food and Drug Administration (FDA)

Haim Belmaker (985 words) [view diff] exact match in snippet view article find links to article

brain as a treatment for depression, the first to study it in animal models of depression, and co-edited the first handbook of this treatment for psychiatric

Serotonin–norepinephrine reuptake inhibitor (7,687 words) [view diff] exact match in snippet view article find links to article

that exhibited excellent selectivity and was efficacious in animal models of depression, pain, and thermoregulatory dysfunction. Milnacipran is structurally

Oxytocin (11,781 words) [view diff] exact match in snippet view article find links to article

encountered again. Oxytocin produces antidepressant-like effects in animal models of depression, and a deficit of it may be involved in the pathophysiology of

Stimulant (13,076 words) [view diff] exact match in snippet view article find links to article

(2005). "Psychostimulant withdrawal as an inducing condition in animal models of depression". Neurosci Biobehav Rev. 29 (4–5): 675–706. doi:10.1016/j.neubiorev

Mental disorder (20,219 words) [view diff] exact match in snippet view article find links to article

S2CID 25469071. Matthews K, Christmas D, Swan J, Sorrell E (2005). "Animal models of depression: navigating through the clinical fog". Neuroscience & Biobehavioral

Epigenetics of depression (4,421 words) [view diff] exact match in snippet view article find links to article

reverse the reduced hippocampal brain signaling observed in animal models of depression. BDNF is involved in depression through its effects on serotonin

Depression and immune function (6,981 words) [view diff] exact match in snippet view article find links to article

MA, Prall K, Dwivedi Y (July 2017). "The recent progress in animal models of depression". Progress in Neuro-Psychopharmacology & Biological Psychiatry