Find link

language:

Find link is a tool written by Edward Betts.

searching for Beta-peptide 64 found (71 total)

Amyloid beta (4,769 words) [view diff] no match in snippet view article find links to article

PMC 3148408. PMID 21726530. Hamley IW (October 2012). "The amyloid beta peptide: a chemist's perspective. Role in Alzheimer's and fibrillization" (PDF)

Amyloid-beta precursor protein secretase (275 words) [view diff] no match in snippet view article find links to article

beta-secretase 1 (BACE) and gamma-secretase (γ-secretase) produces the amyloid-beta peptide fragment that aggregates into clumps called amyloid plaques in the brains

Cerebral amyloid angiopathy (1,768 words) [view diff] no match in snippet view article find links to article

Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the central

Neprilysin (2,697 words) [view diff] no match in snippet view article find links to article

neurotensin, oxytocin, and bradykinin. It also degrades the amyloid beta peptide whose abnormal folding and aggregation in neural tissue has been implicated

Protein AATF (1,226 words) [view diff] no match in snippet view article find links to article

Guo Q, Xie J (Feb 2004). "AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4". The Journal of Biological Chemistry

Soluble low-density lipoprotein receptor-related protein (185 words) [view diff] no match in snippet view article find links to article

bind to and neutralize anywhere from 70 to 90 percent of the amyloid-beta peptide that also naturally circulates in healthy human or mouse plasma. Impairment

Amyloid-beta precursor protein (5,525 words) [view diff] no match in snippet view article find links to article

A, Stern D (Oct 1997). "An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease". Nature. 389 (6652):

T cell receptor T cell therapy (601 words) [view diff] no match in snippet view article find links to article

cancer immunotherapy. TCR-T therapies use heterodimers made of alpha and beta peptide chains to recognize MHC-presented polypeptide fragments molecules. Unlike

CI-1017 (404 words) [view diff] no match in snippet view article find links to article

only at very high doses. It also inhibits production of amyloidogenic A beta peptide and increases secretion of soluble amyloid precursor protein via stimulation

HSD17B10 (1,930 words) [view diff] no match in snippet view article find links to article

A, Stern D (Oct 1997). "An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease". Nature. 389 (6652):

Beta-secretase 2 (1,586 words) [view diff] no match in snippet view article find links to article

amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated

Peroxidase (719 words) [view diff] no match in snippet view article find links to article

Retrieved 30 May 2019. Atamna H, Boyle K (February 2006). "Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies

Biomarkers of Alzheimer's disease (1,704 words) [view diff] no match in snippet view article find links to article

soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide". Biophysical Journal. 94 (7): 2752–2766. Bibcode:2008BpJ....94.2752T

Collagen, type XXV, alpha 1 (480 words) [view diff] exact match in snippet view article find links to article

Alzheimer's disease-associated CLAC protein and identification of an amyloid beta-peptide-binding site". J. Biol. Chem. 280 (2): 1007–15. doi:10.1074/jbc.M403628200

PAWR (1,352 words) [view diff] no match in snippet view article find links to article

Guo Q, Xie J (Feb 2004). "AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4". The Journal of Biological Chemistry

LRP1B (648 words) [view diff] no match in snippet view article find links to article

beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production". J. Biol. Chem. 279 (28): 29639–46. doi:10.1074/jbc.M313893200

Cyanophycinase (648 words) [view diff] exact match in snippet view article find links to article

1999.00479.x. PMID 10429200. A.M. Law et al. "The structural basis of beta-peptide-specific cleavage by the serine protease cyanophycinase". J. Mol. Biol

Journal of Peptide Science (215 words) [view diff] exact match in snippet view article find links to article

insects", Volume 6, Issue 10, Oct 2000, Pages: 497–511, Otvos L "Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: Binding sites

DDIT4 (1,505 words) [view diff] exact match in snippet view article find links to article

"Identification of amyloid beta-peptide responsive genes by cDNA microarray technology: involvement of RTP801 in amyloid beta-peptide toxicity". Experimental

Meningoencephalitis (1,107 words) [view diff] no match in snippet view article find links to article

meningoencephalitis at the primary stage of infection. Antibodies targeting amyloid beta peptide proteins which have been used during research on Alzheimer's disease

Early-onset Alzheimer's disease (3,621 words) [view diff] no match in snippet view article find links to article

been identified as part of the enzymatic complex that cleaves amyloid-beta peptide from APP. The gene contains 14 exons, and the coding portion is estimated

Bapineuzumab (835 words) [view diff] no match in snippet view article find links to article

"Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation". Scientific Reports. 3 (3): 1302. Bibcode:2013NatSR

Dennis J. Selkoe (1,008 words) [view diff] exact match in snippet view article find links to article

chronic diseases: lessons learned from Alzheimer's disease (2007) Amyloid beta-peptide is produced by cultured cells during normal metabolism: a reprise (2006)

SYNPR (493 words) [view diff] exact match in snippet view article find links to article

nitration of a synaptic protein synaptophysin contributes to amyloid beta-peptide-induced cholinergic dysfunction". Mol. Psychiatry. 8 (4): 407–12. doi:10

GPR3 (1,905 words) [view diff] no match in snippet view article find links to article

(February 2009). "The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons". Science. 323 (5916): 946–951. Bibcode:2009Sci

Samuel Weiss (neurobiologist) (699 words) [view diff] exact match in snippet view article

(GRMs/mGluRs) have been implicated in the aetiology of schizophrenia, in amyloid beta-peptide toxicity, Creutzfeldt–Jakob disease and Fragile X syndrome. His discovery

RTN2 (469 words) [view diff] no match in snippet view article find links to article

(2004). "Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation". Nat. Med. 10 (9): 959–65. doi:10.1038/nm1088. PMID 15286784

George M. Martin (2,090 words) [view diff] exact match in snippet view article find links to article

calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide". NeuroReport. 8 (1): 379–383. doi:10.1097/00001756-199612200-00074.

Sex differences in memory (1,896 words) [view diff] no match in snippet view article find links to article

Alzheimer's disease than men: gender and mitochondrial toxicity of amyloid-beta peptide". Journal of Alzheimer's Disease (Review). 20 (Suppl 2): S527–533. doi:10

Insulin-degrading enzyme (2,074 words) [view diff] no match in snippet view article find links to article

(November 2010). "Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading

RTN1 (1,052 words) [view diff] no match in snippet view article find links to article

(2004). "Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation". Nat. Med. 10 (9): 959–65. doi:10.1038/nm1088. PMID 15286784

Intracranial hemorrhage (3,586 words) [view diff] no match in snippet view article find links to article

subject. Cerebral amyloid angiopathy (CAA) is the deposition of Amyloid beta peptide protein within the brain. Accumulation of such peptide proteins within

Biochemistry of Alzheimer's disease (7,759 words) [view diff] exact match in snippet view article find links to article

Jarvet J, Gräslund A (July 2006). "15N relaxation study of the amyloid beta-peptide: structural propensities and persistence length". Magnetic Resonance

Blarcamesine (793 words) [view diff] no match in snippet view article find links to article

which cleaves the amyloid precursor protein to produce the amyloid-beta peptide. These amyloid-beta peptides aggregate together to form plaques. This

Glucagon-like peptide-1 (3,369 words) [view diff] no match in snippet view article find links to article

NH (June 2003). "Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by

TPI1 (2,069 words) [view diff] no match in snippet view article find links to article

discoveries in Alzheimer's disease research have indicated that amyloid beta peptide-induced nitro-oxidative damage promotes the nitrotyrosination of TPI

PLCD1 (904 words) [view diff] no match in snippet view article find links to article

PMC 162146. PMID 12805215. Kim JY, Kim H, Lee SG, et al. (2003). "Amyloid beta peptide (Abeta42) activates PLC-delta1 promoter through the NF-kappaB binding

RTN3 (937 words) [view diff] no match in snippet view article find links to article

(2004). "Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation". Nat. Med. 10 (9): 959–65. doi:10.1038/nm1088. PMID 15286784

APBA2 (1,237 words) [view diff] no match in snippet view article find links to article

and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This

Phenserine (2,538 words) [view diff] no match in snippet view article find links to article

Hureau C, Collin F (April 2018). "Oxidative stress and the amyloid beta peptide in Alzheimer's disease". Redox Biology. 14: 450–464. doi:10.1016/j.redox

Angiotensin-converting enzyme (2,536 words) [view diff] no match in snippet view article find links to article

blood-brain-barrier (BBB) could enhance the activity of major amyloid-beta peptide degrading enzymes like neprilysin in the brain resulting in a slower

FBXW7 (1,515 words) [view diff] no match in snippet view article find links to article

interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production". J. Neurochem. 82 (6): 1540–8. doi:10.1046/j.1471-4159.2002

CALHM1 (898 words) [view diff] no match in snippet view article find links to article

might facilitate the proteolytic degradation of the cerebral amyloid beta peptide, a culprit in AD pathogenesis. CALHM1 is expressed in taste bud cells

APBA1 (1,386 words) [view diff] no match in snippet view article find links to article

and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This

Isoflurane (1,714 words) [view diff] no match in snippet view article find links to article

interact with three amino acid residues (G29, A30 and I31) of amyloid beta peptide and induce aggregation. This area is important as "some of the commonly

Alison Downard (667 words) [view diff] exact match in snippet view article find links to article

Downard; Andrew D Abell (1 January 2010). "Electrochemistry of ferrocenoyl beta-peptide monolayers on gold". Langmuir. 26 (2): 1334–1339. doi:10.1021/LA902402T

Sara Snogerup Linse (898 words) [view diff] no match in snippet view article find links to article

has demonstrated that the process of nucleation and growth of amyloid-beta peptide occurs in two phases; first the amyloid fibrils form and then monomers

Common degu (3,020 words) [view diff] exact match in snippet view article find links to article

Merabachvili, G.; Aldunate, R.; et al. (2004), "Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degus", Neurobiol

Neurodegenerative disease (7,018 words) [view diff] no match in snippet view article find links to article

Culwell AR, Oltersdorf T, et al. (June 1990). "Cleavage of amyloid beta peptide during constitutive processing of its precursor". Science. 248 (4959):

Low-affinity nerve growth factor receptor (4,235 words) [view diff] exact match in snippet view article find links to article

aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation". The EMBO Journal. 25 (9): 1997–2006. doi:10.1038/sj.emboj

MARCH5 (1,266 words) [view diff] no match in snippet view article find links to article

6-hydroxydopamine, the complex I inhibitor rotenone or Alzheimer's-related amyloid beta peptide. MARCH5 is also involved in the removal of proteins associated with specific

Mitochondria associated membranes (1,419 words) [view diff] no match in snippet view article find links to article

disease have presented results that indicated the accumulation of amyloid beta peptide in the brain which in turn leads to the amyloid cascade suggestion. Also

Caspase 3 (3,392 words) [view diff] no match in snippet view article find links to article

cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation". Cell. 97 (3): 395–406. doi:10.1016/s0092-8674(00)80748-5

Allan Butterfield (819 words) [view diff] no match in snippet view article find links to article

Institutes of Health (NIH), came to this conclusion by comparing amyloid beta peptide in an animal model to the same compound in humans. Later, he was appointed

Apoptosis (10,629 words) [view diff] no match in snippet view article find links to article

Bieberich CJ, Haudenschild CC, Jay G (January 1995). "The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice"

Down syndrome (15,021 words) [view diff] no match in snippet view article find links to article

dementia that occurs in Down syndrome is due to an excess of amyloid beta peptide produced in the brain and is similar to Alzheimer's disease, which also

Estrogen receptor beta (4,522 words) [view diff] no match in snippet view article find links to article

The pathology of AD is also associated with accumulation of amyloid beta peptide (Aβ). While a proper concentration of Aβ in the brain is important for

Default mode network (7,014 words) [view diff] no match in snippet view article find links to article

metabolic rate from continuous activation of DMN causes more amyloid-beta peptide to accumulate in these DMN areas. These amyloid-beta peptides disrupt

Cancer immunotherapy (9,943 words) [view diff] no match in snippet view article find links to article

lymphoma (DLBCL). TCR-T therapies use heterodimers made of alpha and beta peptide chains to recognize MHC-presented polypeptide fragments molecules. Unlike

Buntanetap (825 words) [view diff] no match in snippet view article find links to article

experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice". The Journal of Pharmacology and Experimental

NAD(P)H dehydrogenase (quinone 1) (3,419 words) [view diff] exact match in snippet view article

2000). "The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease". Progress in Neurobiology. 62 (6): 633–48. doi:10

Joseph Buxbaum (2,412 words) [view diff] exact match in snippet view article find links to article

J. D. (2000-03-22). "Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline". JAMA. 283 (12): 1571–1577. doi:10

Alzheimer's disease in African Americans (4,450 words) [view diff] no match in snippet view article find links to article

cleaved first by β-secretase and then γ-secretase to produce amyloid beta peptide. Most of the APP mutations cluster near the β-secretase and γ-secretase

Epigenetics of physical exercise (8,910 words) [view diff] no match in snippet view article find links to article

of microglia and astrocytes caused by excessive build-up of amyloid beta peptide plaque upon the brain. The amyloid beta plaque causes the microglia and