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searching for CDC6 44 found (60 total)

alternate case: cDC6

Origin recognition complex (2,335 words) [view diff] case mismatch in snippet view article find links to article

foundation for assembly of the pre-replication complex (pre-RC), which includes Cdc6, Tah11 (a.k.a. Cdt1), and the Mcm2-Mcm7 complex. Pre-RC assembly during G1

Control of chromosome duplication (2,036 words) [view diff] case mismatch in snippet view article find links to article

cycle, but in others it dissociates at specific stages of the cell cycle. Cdc6 and Cdt1 assemble on the ORC and recruit the Mcm proteins. Homologs for these

Origin of replication (12,563 words) [view diff] case mismatch in snippet view article find links to article

the initiator, Orc1/Cdc6 in archaea, which binds to ORB regions. Archaeal genomes typically encode multiple paralogs of Orc1/Cdc6 that vary substantially

Licensing factor (583 words) [view diff] case mismatch in snippet view article find links to article

the rest of the cycle begins. Two of the proteins synthesised are called Cdc6 and Cdt1 and are only synthesised in G1 phase. These two together bind to

Eukaryotic DNA replication (14,643 words) [view diff] case mismatch in snippet view article find links to article

replication origin. In late mitosis, the Cdc6 protein joins the bound ORC followed by binding the Cdt1-Mcm2-7 complex. ORC, Cdc6, and Cdt1 are all required to load

Minichromosome maintenance (3,042 words) [view diff] case mismatch in snippet view article find links to article

a six subunit complex (Orc1-6). During the G1 phase of the cell cycle, Cdc6 is recruited by ORC to form a launching pad for the loading of two head-to-head

DNA re-replication (2,860 words) [view diff] case mismatch in snippet view article find links to article

recruits the AAA+ ATPase Cdc6 and the coiled-coil domain protein Cdt1. Cdt1 binding and the ATPase activity of ORC and Cdc6 facilitate the loading of

DNA replication factor CDT1 (1,439 words) [view diff] exact match in snippet view article find links to article

recognize and bind to DNA replication origins. CDT1, along with the protein CDC6, are then recruited to the forming pre-RC, followed by minichromosome maintenance

E2F (1,910 words) [view diff] case mismatch in snippet view article find links to article

(for example DNA polymerase, thymidine kinase, dihydrofolate reductase and cdc6), and chromosomal replication (replication origin-binding protein HsOrc1

DNA polymerase epsilon (336 words) [view diff] case mismatch in snippet view article find links to article

Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor

Carpediemonas (1,523 words) [view diff] case mismatch in snippet view article find links to article

lack the DNA replication proteins of the origin recognition complex (ORC), Cdc6, some components of the GINS complex and some subunits of polymerases delta

HLA-F (4,439 words) [view diff] case mismatch in snippet view article find links to article

phosphorylation (cyclin-dependent kinase) and removal of the Saccharomyces cerevisiae Cdc6 protein, which is crucial for functional DNA replication. The Major Histocompatibility

POLE4 (264 words) [view diff] case mismatch in snippet view article find links to article

Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor

POLE2 (523 words) [view diff] case mismatch in snippet view article find links to article

Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor

ORC3 (974 words) [view diff] case mismatch in snippet view article find links to article

as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC

Replicon (genetics) (634 words) [view diff] case mismatch in snippet view article

Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor

ORC6 (881 words) [view diff] case mismatch in snippet view article find links to article

as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC

ORC5 (983 words) [view diff] case mismatch in snippet view article find links to article

as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC

POLD3 (740 words) [view diff] case mismatch in snippet view article find links to article

Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor

ORC4 (1,126 words) [view diff] case mismatch in snippet view article find links to article

as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC

POLE (gene) (1,103 words) [view diff] case mismatch in snippet view article

Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor

Paraphago (39 words) [view diff] exact match in snippet view article find links to article

11305730 ITIS: 639818 IUCN: 182180 Open Tree of Life: 3625910 Plazi: 89552C7B-CDC6-6680-A9D9-B7032D7C55F2 WoRMS: 1019009 ZooBank: 6C2F0909-E9FE-44F0-BDD8-AE47F076DEBB

Menziesichthys (99 words) [view diff] exact match in snippet view article find links to article

11371629 ITIS: 690554 Open Tree of Life: 3631949 Plazi: FA4B819E-AD84-8156-64CB-5AAEEFEA1B0E WoRMS: 281550 ZooBank: AE1BB747-CDC6-4CB3-B53E-4367884D214A

Thermoplasma acidophilum (683 words) [view diff] case mismatch in snippet view article find links to article

thermophilic archaeon, Thermoplasma acidophilum by interactions with GINS and Cdc6-2". Extremophiles. 18 (5): 915–924. doi:10.1007/s00792-014-0673-6. PMID 25107272

Picrophilus torridus (512 words) [view diff] case mismatch in snippet view article find links to article

Saha, Swati (Jan 2014). "Characterization of the Replication Initiator Orc1/Cdc6 from the Archaeon Picrophilus torridus". Journal of Bacteriology. 196 (2):

Cell division cycle 7-related protein kinase (1,746 words) [view diff] case mismatch in snippet view article find links to article

complex (pre-RC) by binding to the chromatin and other aiding proteins (Cdc6 and Cdt1).[citation needed] Mitosis occurs during M phase of the cell cycle

40S ribosomal protein S27a (929 words) [view diff] exact match in snippet view article find links to article

(2000). "Cell cycle– and cell growth–regulated proteolysis of mammalian CDC6 is dependent on APC–CDH1". Genes Dev. 14 (18): 2330–43. doi:10.1101/gad.832500

Synexpression (468 words) [view diff] case mismatch in snippet view article find links to article

co-evolution. One simplified example of a synexpression group is the genes cdc6, cdc3, cdc46, and swi4 in yeast, which are all co-expressed early in the

Microbispora (257 words) [view diff] case mismatch in snippet view article find links to article

1014600 ITIS: 957607 LPSN: microbispora.html MycoBank: 27359 NCBI: 2005 NZOR: dcb0990b-cdc6-48f6-80ff-1260fab59397 Open Tree of Life: 751345 WoRMS: 559779

Cell division control protein 4 (1,874 words) [view diff] case mismatch in snippet view article find links to article

activation of the HTA1-HTB1 locus degradation of the phosphorylated form of Cdc6 Swi5 is a transcriptional activator of Sic1, which inhibits S-phase CDKs

PPP2CA (1,716 words) [view diff] case mismatch in snippet view article find links to article

"PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells". Molecular and Cellular Biology

CDC45-related protein (1,112 words) [view diff] case mismatch in snippet view article find links to article

Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase

Menziesichthys bacescui (59 words) [view diff] exact match in snippet view article find links to article

11371629 ITIS: 690554 Open Tree of Life: 3631949 Plazi: FA4B819E-AD84-8156-64CB-5AAEEFEA1B0E WoRMS: 281550 ZooBank: AE1BB747-CDC6-4CB3-B53E-4367884D214A

PPP2R1A (1,345 words) [view diff] case mismatch in snippet view article find links to article

"PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells". Mol. Cell. Biol. 20 (3): 1021–1029

Geminin (1,608 words) [view diff] exact match in snippet view article find links to article

2309. PMID 11125146. Bermejo R, Vilaboa N, Calés C (2002). "Regulation of CDC6, geminin, and CDT1 in human cells that undergo polyploidization". Molecular

G2 phase (2,818 words) [view diff] case mismatch in snippet view article find links to article

G2 checkpoint activity, perhaps through a stabilizing phosphorylation on Cdc6. CDK2-/- cells also have aberrantly high levels of Cdc25A. Cyclin A2/CDK1

Sulfolobus (2,187 words) [view diff] exact match in snippet view article find links to article

These genes include DNA polymerase, primase (including two subunits), MCM, CDC6/ORC1, RPA, RPC, and PCNA. In 2004, the origins of DNA replication of Sulfolobus

BCK2 (1,015 words) [view diff] exact match in snippet view article find links to article

Breeden LL (May 1997). "A novel Mcm1-dependent element in the SWI4, CLN3, CDC6, and CDC47 promoters activates M/G1-specific transcription". Genes & Development

Zoi Lygerou (608 words) [view diff] case mismatch in snippet view article find links to article

this cellular mechanism is controlled via Cdc proteins such as Cdc18 and Cdc6 in yeast and humans, along with Cdt proteins such as Cdt1. Lygerou's research

DNA unwinding element (2,303 words) [view diff] case mismatch in snippet view article find links to article

ISBN 9780128047354. PMC 5551690. PMID 27241926. Bell SD (2012). "Archaeal Orc1/Cdc6 Proteins". The Eukaryotic Replisome: A Guide to Protein Structure and Function

Cyclin-dependent kinase 2 (4,286 words) [view diff] exact match in snippet view article find links to article

COMPLEX WITH A PEPTIDE CONTAINING BOTH THE SUBSTRATE AND RECRUITMENT SITES OF CDC6 2cjm: MECHANISM OF CDK INHIBITION BY ACTIVE SITE PHOSPHORYLATION: CDK2 Y15P

Sic1 (2,608 words) [view diff] case mismatch in snippet view article find links to article

PMID 9017392. Calzada A, Sacristán M, Sánchez E, Bueno A (July 2001). "Cdc6 cooperates with Sic1 and Hct1 to inactivate mitotic cyclin-dependent kinases"

Anindya Dutta (2,387 words) [view diff] case mismatch in snippet view article find links to article

replication initiation factors and their regulators (Orc3, Orc4, Orc5, Orc6, Cdc6, Cdt1, Cdc45, Mcm10, geminin) and identified how the geminin-Cdt1 balance

POLD1 (7,977 words) [view diff] case mismatch in snippet view article find links to article

Schizosaccharomyces pombe A (catalytic) p125 POLD1-Chr 19q13.3 Pold1-Chr 7B4 POL3-Chr IV cdc6-Chr II B (accessory) p50 POLD2-Chr 7p13 Pold2-Chr 11A2 POL31-Chr X cdc1-Chr