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searching for CYP1A1 27 found (73 total)

alternate case: cYP1A1

Benzopyrene (614 words) [view diff] exact match in snippet view article find links to article

relates to the activity of cytochrome P450 subclass 1A1 (CYP1A1). Seemingly, the high activity of CYP1A1 in the intestinal mucosa prevents major amounts of

6-Formylindolo(3,2-b)carbazole (4,634 words) [view diff] exact match in snippet view article

its rapid metabolic degradation by CYP1A1. In the first analyses of the metabolism of FICZ, human recombinant CYP1A1 enzyme and S9 fractions prepared from

Sudan I (2,497 words) [view diff] exact match in snippet view article find links to article

Sultan I oxidation were also demonstrated with human CYP enzymes, with CYP1A1 being the major enzyme involved in the oxidation of Sudan I in human tissues

Pharmacoepigenetics (4,224 words) [view diff] exact match in snippet view article find links to article

could affect the efficiency and drug response to the anti-HIV therapy. CYP1A1 is a protein that is well known for its role in chemical compounds and drug

Angelicin (3,002 words) [view diff] exact match in snippet view article find links to article

catalytic activity performed by CYP1A1 regardless the presence of UV light. Angelicin triggers the gene expression of CYP1A1 by activation of AhR when no

Alpinia officinarum (599 words) [view diff] exact match in snippet view article find links to article

Ciolino, H. P.; Yeh, G. C. (1999). "The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor". British

Galangin (421 words) [view diff] exact match in snippet view article find links to article

Ciolino, H. P.; Yeh, G. C. (1999). "The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor". British

Epigenetic effects of smoking (1,902 words) [view diff] exact match in snippet view article find links to article

affected by differential methylation are the CYP1A1 xenobiotic response element, AHRR, and F2RL3. CYP1A1 is critical to the detoxification of carcinogens

Benzo(c)fluorene (2,141 words) [view diff] exact match in snippet view article

reacts instead. The type of cytochrome P 450 involved is thought to be CYP1A1. The biotransformation is depicted in the image below. First benzo[c]fluorene

Ilya B. Tsyrlov (1,337 words) [view diff] exact match in snippet view article find links to article

immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2”. Archives of Biochemistry and Biophysics 307:259-266. DOI:10

Harmalol (189 words) [view diff] exact match in snippet view article find links to article

(2012). "Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms". Food Chem Toxicol

Harmol (211 words) [view diff] exact match in snippet view article find links to article

"Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol". Toxicol Lett. 208 (1): 51–61. doi:10.1016/j.toxlet

Microsome (1,551 words) [view diff] exact match in snippet view article find links to article

Schunck WH, Roots I (2001). "Co-expression of human cytochrome P4501A1 (CYP1A1) variants and human NADPH-cytochrome P450 reductase in the baculovirus/insect

Olokizumab (1,089 words) [view diff] exact match in snippet view article find links to article

cryopreserved hepatocytes, olokizumab reversed the inhibitory effect of IL-6 on CYP1A1/2, 2B6, 2C9, 3A4/5 and 2C19 activity, as well as on NTCP activity. Thus

KLF4 (6,840 words) [view diff] exact match in snippet view article find links to article

1998). "The gut-enriched Krüppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion". The Journal of Biological Chemistry

Aryl hydrocarbon receptor nuclear translocator (1,770 words) [view diff] exact match in snippet view article find links to article

90 Inhibitors Suppress Aryl Hydrocarbon Receptor-Mediated Activation of CYP1A1 and CYP1B1 Transcription and DNA Adduct Formation". Cancer Prevention Research

Cyclin T1 (1,358 words) [view diff] case mismatch in snippet view article find links to article

differential phosphorylation of C-terminal domain of RNA polymerase II at cyp1a1 promoter". J. Biol. Chem. 278 (45): 44041–8. doi:10.1074/jbc.M306443200

Chlorethoxyfos (1,945 words) [view diff] exact match in snippet view article find links to article

most important enzymes in metabolism of organophosphorus compounds are CYP1A1, CYP2B6, CYP3A4 and CYP2C19. The first three cytochromes catalyze the oxidative

Alpha-1 blocker (4,243 words) [view diff] exact match in snippet view article find links to article

edema, hypotension, dyspnea, vertigo, nervousness, rash, blurred vision CYP1A1 Terazosin Alpha-1 Nervousness, vertigo, palpitations, tachycardia, chest

Specialized pro-resolving mediators (7,270 words) [view diff] case mismatch in snippet view article find links to article

either ALOX15, by a bacterial or mammalian cytochrome P450 monooxygenase (Cyp1a1, Cyp1a2, or Cyp1b1 in mice; see CYP450 §§ CYP families in humans and P450s

Atya Kapley (833 words) [view diff] exact match in snippet view article find links to article

Digumarti, Raghunadha; Jamil, Kaiser (2015). "Association of The Common CYP1A1*2C Variant (Ile462Val Polymorphism) with Chronic Myeloid Leukemia (CML)

Circumventricular organs (4,289 words) [view diff] case mismatch in snippet view article find links to article

K.D.; Derbenev A.V. (2012). "Increased neuronal activity in the OVLT of Cyp1a1-Ren2 transgenic rats with inducible Ang II-dependent malignant hypertension"

Eicosanoid (9,517 words) [view diff] exact match in snippet view article find links to article

omega oxidation reaction. The human cytochrome P450 (CYP) epoxygenases, CYP1A1, CYP1A2, CYP2C8, CYP2C9, CYP2C18, CYP2C19, CYP2E1, CYP2J2, and CYP2S1 metabolize

Medical cannabis (9,930 words) [view diff] exact match in snippet view article find links to article

products of primarily CYP2C19 and CYP3A4 activity, with potential activity of CYP1A1, CYP1A2, CYP2C9, and CYP2D6. Similar to delta-9-THC, a majority of CBD is

2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (1,541 words) [view diff] exact match in snippet view article

Mutation Research. 376: 37-41. Schweikl, H., et al (1993) Expression of CYP1A1 and CYP1A2 genes in human liver. Pharmacogenetics. 3:239 -249. Roberts-Thompson

Endocrine disruptor (16,616 words) [view diff] exact match in snippet view article find links to article

Zhang CM, Ma XM, Wei WG, Zhang P, Bai ZP (April 2008). "Expression of AhR, CYP1A1, GSTA1, c-fos and TGF-alpha in skin lesions from dioxin-exposed humans with

HepaRG (2,666 words) [view diff] exact match in snippet view article find links to article

hepatic nuclear factors. They also possess functional levels of phase I (CYP (CYP1A1/2, CYP2B6, CYP2Cs, CYP3A4, etc.) and II (UGT1A1, GSTA1, GSTA4, GSTM1) drug