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searching for Caspase-2 30 found (36 total)

alternate case: caspase-2

Caspase 2 (921 words) [view diff] no match in snippet view article find links to article

Caspase 2 also known as CASP2 is an enzyme that, in humans, is encoded by the CASP2 gene. CASP2 orthologs have been identified in nearly all mammals for

CRADD (939 words) [view diff] no match in snippet view article find links to article

Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor

Caspase-10 (249 words) [view diff] exact match in snippet view article find links to article

sequence of Leu-Gln-Thr-Asp!Gly Caspase-10 is an initiator caspase, as are caspase-2 (EC 3.4.22.55), caspase-8 (EC 3.4.22.61) and caspase-9 (EC 3.4.22.62)

CARD (domain) (1,429 words) [view diff] exact match in snippet view article

peptidase (interleukin 1, beta, convertase; ICE) [3][permanent dead link] caspase-2: apoptosis-related cysteine peptidase [4][permanent dead link] caspase-4:

LRDD (788 words) [view diff] no match in snippet view article find links to article

complex formed together with the catalytic subunit of DNA-PK (DNA-PKcs)and caspase 2. GRCh38: Ensembl release 89: ENSG00000177595 – Ensembl, May 2017 GRCm38:

BH3 interacting-domain death agonist (1,246 words) [view diff] exact match in snippet view article find links to article

Srinivasula SM, Druilhe A, Fernandes-Alnemri T, Alnemri ES (2002). "Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria"

Anterior ischemic optic neuropathy (2,571 words) [view diff] no match in snippet view article find links to article

gov/). This trial will test the use of a synthetic siRNA that blocks caspase 2, an important enzyme in the apoptosis cycle. In addition to such research

Death regulator Nedd2-like caspase (4,796 words) [view diff] exact match in snippet view article find links to article

considered orthologs of caspase Dronc, the one that resembles it the most is Caspase-2. However, Nedd2-like caspase is the functional homolog of mammalian Caspase-9

Caspase (3,113 words) [view diff] no match in snippet view article find links to article

removal. Apoptotic caspases are subcategorised as: Initiator Caspases (Caspase 2, Caspase 8, Caspase 9, Caspase 10) Executioner Caspases (Caspase 3, Caspase

Caspase 7 (669 words) [view diff] exact match in snippet view article find links to article

Srinivasula SM, Druilhe A, Fernandes-Alnemri T, Alnemri ES (Apr 2002). "Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria"

Xenopus (5,805 words) [view diff] exact match in snippet view article find links to article

Recently, oocytes were used recently to study the biochemical mechanisms of caspase-2 activation; importantly, this mechanism turns out to be conserved in mammals

Caspase 10 (1,469 words) [view diff] exact match in snippet view article find links to article

Druilhe Anne, Fernandes-Alnemri Teresa, Alnemri Emad S (April 2002). "Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria"

Caspase 6 (1,629 words) [view diff] exact match in snippet view article find links to article

Srinivasula SM, Druilhe A, Fernandes-Alnemri T, Alnemri ES (Apr 2002). "Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria"

A. Thomas Look (1,392 words) [view diff] exact match in snippet view article find links to article

define distinct oncogenic subgroups in T-ALL Discovery of CHK1 suppressed caspase-2 apoptotic pathway in response to DNA damage Discovery of activating ALK

ContraPest (910 words) [view diff] exact match in snippet view article find links to article

Kolesnick, Richard N.; Yuan, Junying; Flavell, Richard A. (2003-01-01). "Bax, caspase-2, and caspase-3 are required for ovarian follicle loss caused by 4-vinylcyclohexene

Vinylcyclohexene dioxide (527 words) [view diff] exact match in snippet view article find links to article

Kolesnick, Richard N.; Yuan, Junying; Flavell, Richard A. (2003-01-01). "Bax, caspase-2, and caspase-3 are required for ovarian follicle loss caused by 4-vinylcyclohexene

HK2 (2,505 words) [view diff] exact match in snippet view article find links to article

the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanism". Cell Cycle. 8 (20): 3355–64. doi:10.4161/cc.8.20

MZB1 (559 words) [view diff] exact match in snippet view article find links to article

F, Cooper NR (August 2001). "Characterization of a novel proapoptotic caspase-2- and caspase-9-binding protein". The Journal of Biological Chemistry.

GOLGA3 (905 words) [view diff] exact match in snippet view article find links to article

PMC 16267. PMID 10737800. Mancini M, Machamer CE, Roy S, et al. (2000). "Caspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis"

AIFM1 (1,545 words) [view diff] exact match in snippet view article find links to article

Prévost MC, Alzari PM, Kroemer G (January 1999). "Mitochondrial release of caspase-2 and -9 during the apoptotic process". The Journal of Experimental Medicine

Bcl-2 (4,868 words) [view diff] exact match in snippet view article find links to article

Srinivasula SM, Druilhe A, Fernandes-Alnemri T, Alnemri ES (April 2002). "Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria"

NLRP1 (2,089 words) [view diff] no match in snippet view article find links to article

protein-protein interactions. The NLRP1 protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated

Caspase 3 (3,392 words) [view diff] exact match in snippet view article find links to article

Srinivasula SM, Druilhe A, Fernandes-Alnemri T, Alnemri ES (April 2002). "Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria"

Tetrapeptide (1,938 words) [view diff] exact match in snippet view article find links to article

accompanied by the processing of activation of caspase-3 and potentially caspase-2. Benzyloxycarbonyl-Val-Ala-Asp-(OMe)-fluoromethylketone (zVAD.fmk), a

Caspase-9 (4,330 words) [view diff] exact match in snippet view article find links to article

Srinivasula SM, Druilhe A, Fernandes-Alnemri T, Alnemri ES (April 2002). "Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria"

James J. Chou (1,422 words) [view diff] exact match in snippet view article find links to article

Structure of the RAIDD CARD Domain and Model for CARD/CARD Interaction in Caspase-2 and Caspase-9 Recruitment". Cell. 94 (2): 171–80. doi:10.1016/s0092-8674(00)81417-8

RNA silencing (5,475 words) [view diff] no match in snippet view article find links to article

disorders QPI-1007 Non-arteritic anterior ischaemic optic neuropathy Caspase 2 Ocular and retinal disorders AGN211745 Age-related macular degeneration

Karen Ashe (2,715 words) [view diff] exact match in snippet view article find links to article

Hlynialuk C, Zahs K, Ramsden M, Cleary J, Ashe KH (November 2016). "Caspase-2 cleavage of tau reversibly impairs memory". Nat Med. 22 (11): 1268–1276

RIPK1 (4,148 words) [view diff] exact match in snippet view article find links to article

(February 1997). "CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP". Cancer

RBM10 (5,530 words) [view diff] no match in snippet view article find links to article

Sutherland LC, Wu JY (October 2008). "Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5". Proceedings of