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Longer titles found: Cyclooxygenase-2 inhibitor (view)

searching for Cyclooxygenase-2 142 found (178 total)

Discovery and development of cyclooxygenase 2 inhibitors (4,463 words) [view diff] no match in snippet view article find links to article

Cyclooxygenase Cyclooxygenase 1 Cyclooxygenase 2 NSAID COX-2 selective inhibitor Marnett, L. J.; Kalgutkar, A. S. (1999). "Cyclooxygenase 2 inhibitors: Discovery

Rebamipide (399 words) [view diff] exact match in snippet view article find links to article

scavenging free radicals, and temporarily activating genes encoding cyclooxygenase-2. Studies have shown that rebamipide can fight the damaging effects

Amyrin (413 words) [view diff] no match in snippet view article find links to article

inhibiting the production of cytokines and expression of NF-κB, CREB and cyclooxygenase 2. Merck Index, 11th Edition, 653 Merck Index, 11th Edition, 654 Saimaru

Celecoxib (6,032 words) [view diff] exact match in snippet view article find links to article

"Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluorome

Cremastra appendiculata (163 words) [view diff] exact match in snippet view article find links to article

activities and inhibits UVB-induced skin inflammation through reduced cyclooxygenase-2 expression and NF-?B nuclear localization.[jargon] Homoisoflavanone

Cyclooxygenase-3 (2,450 words) [view diff] exact match in snippet view article find links to article

(September 1996). "Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: a possible site of

Quercinol (80 words) [view diff] no match in snippet view article find links to article

has in vitro anti-inflammatory activity, and inhibits the enzymes cyclooxygenase 2, xanthine oxidase, and horseradish peroxidase. Gebhardt P, Dornberger

Karen Seibert (1,586 words) [view diff] exact match in snippet view article find links to article

Representative articles from nearly 100 peer reviewed publications: The Role of Cyclooxygenase-2 in Inflammation. Masferrer JL, Zweifel BS, Colburn SM, Ornberg RL,

Prostaglandin EP1 receptor (2,365 words) [view diff] exact match in snippet view article find links to article

(September 2010). "Targeting the prostaglandin E2 EP1 receptor and cyclooxygenase-2 in the amygdala kindling model in mice". Epilepsy Research. 91 (1):

CUSP9 (883 words) [view diff] exact match in snippet view article find links to article

captopril inhibits angiotensin converting enzyme, celecoxib blocks cyclooxygenase-2, disulfiram blocks aldehyde dehydrogenase, itraconazole blocks Hedgehog

Nonsteroidal anti-inflammatory drug (10,821 words) [view diff] exact match in snippet view article find links to article

cyclooxygenase (COX) enzymes, inhibiting both the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) isoenzymes. This inhibition is competitively reversible (albeit

Mir-542 microRNA precursor family (716 words) [view diff] exact match in snippet view article find links to article

Dixon DA (March 2012). "A common single-nucleotide polymorphism in cyclooxygenase-2 disrupts microRNA-mediated regulation". Oncogene. 31 (12): 1592–8.

Nimesulide (1,751 words) [view diff] exact match in snippet view article find links to article

anti-inflammatory drug (NSAID), acting specifically as a relatively selective cyclooxygenase-2 inhibitor. However, the pharmacological profile of nimesulide is peculiar

Mir-101 microRNA precursor family (332 words) [view diff] exact match in snippet view article find links to article

2012). "Downregulation of miR-101 in gastric cancer correlates with cyclooxygenase-2 overexpression and tumor growth". The FEBS Journal. 279 (22): 4201–12

Tilmacoxib (73 words) [view diff] exact match in snippet view article find links to article

S, Nagano H, Wakasa K, Sugita Y, et al. (August 2003). "JTE-522, a cyclooxygenase-2 inhibitor, is an effective chemopreventive agent against rat experimental

NS-398 (80 words) [view diff] exact match in snippet view article find links to article

Yong Li; Ying Tang; James Cummins; Johnny Huard (2005). "NS-398, a Cyclooxygenase-2-Specific Inhibitor, Delays Skeletal Muscle Healing by Decreasing Regeneration

Date honey (658 words) [view diff] exact match in snippet view article find links to article

anti-inflammatory activity mediated by vascular endothelial growth factor and cyclooxygenase-2 expression in endothelial cells". Nutrition Research. 36 (7): 636–647

Homoisoflavonoid (1,608 words) [view diff] exact match in snippet view article find links to article

activities and inhibits UVB-induced skin inflammation through reduced cyclooxygenase-2 expression and NF-?B nuclear localization. 3-(4'-Methoxybenzyl)-7

Cytochrome (1,107 words) [view diff] no match in snippet view article find links to article

reactions of oxygenic photosynthesis, contains a cytochrome b subunit. Cyclooxygenase 2, an enzyme involved in inflammation, is a cytochrome b protein. In

Prostaglandin EP4 receptor (4,808 words) [view diff] exact match in snippet view article find links to article

Hinz S, Soeters RP, Hofmeyr MD, Millar RP, Jabbour HN (May 2001). "Cyclooxygenase-2 expression and prostaglandin E(2) synthesis are up-regulated in carcinomas

Maryanne Demasi (1,809 words) [view diff] exact match in snippet view article find links to article

inflammatory mediator production: Dissociation between changes in cyclooxygenase-2 expression and eicosanoid synthesis". J Biol Chem. 292 (38): 15993

Rofecoxib (8,141 words) [view diff] no match in snippet view article find links to article

rofecoxib. COX-2 selective inhibitor Discovery and development of cyclooxygenase 2 inhibitors David Graham (epidemiologist) "Vioxx PI" (PDF). FDA. Archived

Oleanolic acid (913 words) [view diff] no match in snippet view article find links to article

induction by IFN-γ of inducible nitric oxide synthase (iNOS) and of cyclooxygenase 2 in mouse macrophages. They are extremely potent inducers of the phase

Gopal Kundu (2,308 words) [view diff] exact match in snippet view article find links to article

PMID 16474166. Jain, S; Chakraborty, G; Kundu, GC (2006). "The Crucial Role of cyclooxygenase-2 in osteopontin-induced PKCα/c-Src/IKKα/β dependent prostate tumor progression

Natsudaidain (95 words) [view diff] exact match in snippet view article find links to article

"Effect of natsudaidain isolated from Citrus plants on TNF-α and cyclooxygenase-2 expression in RBL-2H3 cells". Journal of Pharmacy and Pharmacology

Parecoxib (761 words) [view diff] no match in snippet view article find links to article

doses of 40 mg by IV or IM injection. Discovery and development of cyclooxygenase 2 inhibitors Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias

Cyclooxygenase-1 (2,122 words) [view diff] no match in snippet view article find links to article

effective at reducing cardiac events. Arachidonic acid Cyclooxygenase Cyclooxygenase 2 NSAID Discovery and development of COX-2 selective inhibitors COX-2

Antipyretic (1,156 words) [view diff] exact match in snippet view article find links to article

PMID 21357332. Cryer B, Feldman M (May 1998). "Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs". Am

Darier's disease (2,829 words) [view diff] exact match in snippet view article find links to article

Takagi A, Nakano N, Hara M, Ikeda S, Okumura K, Ogawa H (May 2012). "Cyclooxygenase-2 inhibition restores ultraviolet B-induced downregulation of ATP2A2/SERCA2

Diclofenac (5,352 words) [view diff] exact match in snippet view article find links to article

found the "Use of the nonselective NSAID diclofenac and the selective cyclooxygenase-2 inhibitor rofecoxib was associated with an increased risk of cardiovascular

Polmacoxib (202 words) [view diff] exact match in snippet view article find links to article

Alamuddin N, FitzGerald GA, Skarke C (October 2013). "GCG100649, A Novel Cyclooxygenase-2 Inhibitor, Exhibits a Drug Disposition Profile in Healthy Volunteers

CYP4F8 (1,276 words) [view diff] exact match in snippet view article find links to article

19-hydroxyprostaglandins of human seminal fluid and expression of cyclooxygenase-2, PGH 19-hydroxylase (CYP4F8) and microsomal PGE synthase-1 in seminal

Prostaglandin H2 (505 words) [view diff] exact match in snippet view article find links to article

1021/ja00332a049. ISSN 0002-7863. Hla T, Neilson K (August 1992). "Human cyclooxygenase-2 cDNA". Proceedings of the National Academy of Sciences of the United

Leukotriene B4 receptor 2 (6,788 words) [view diff] exact match in snippet view article find links to article

Shao J, Liang P, DuBois RN, Beauchamp RD (Aug 1998). "Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated

Etoricoxib (1,155 words) [view diff] exact match in snippet view article find links to article

profile and comparison with other agents that selectively inhibit cyclooxygenase-2". The Journal of Pharmacology and Experimental Therapeutics. 296 (2):

CEBPD (1,235 words) [view diff] exact match in snippet view article find links to article

Saunders MA, Yeh H, Deng WG, Wu KK (Mar 2002). "Dynamic regulation of cyclooxygenase-2 promoter activity by isoforms of CCAAT/enhancer-binding proteins".

List of MeSH codes (D27) (5,788 words) [view diff] no match in snippet view article

389.310 – cyclooxygenase inhibitors MeSH D27.505.519.389.310.500 – cyclooxygenase 2 inhibitors MeSH D27.505.519.389.350 – folic acid antagonists MeSH D27

Ursolic acid (1,604 words) [view diff] no match in snippet view article find links to article

kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1" (PDF). Cancer Res. 63 (15):

Rothia mucilaginosa (675 words) [view diff] exact match in snippet view article find links to article

Hiren; Joo, Myungsoo; Hadid, Walid (October 2013). "Induction of Cyclooxygenase-2 Signaling by Stomatococcus mucilaginosus Highlights the Pathogenic

ETV4 (1,071 words) [view diff] exact match in snippet view article find links to article

activator 3, an ets transcription factor, mediates the induction of cyclooxygenase-2 by nitric oxide in colorectal cancer cells". The Journal of Biological

CUGBP2 (1,074 words) [view diff] exact match in snippet view article find links to article

(2003). "Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2". Mol. Cell. 11 (1): 113–26

Prostaglandin EP2 receptor (3,685 words) [view diff] exact match in snippet view article find links to article

WA, Quackenbush J, Konstantopoulos K (August 2003). "Shear-induced cyclooxygenase-2 via a JNK2/c-Jun-dependent pathway regulates prostaglandin receptor

Renin receptor (813 words) [view diff] exact match in snippet view article find links to article

Ichihara A, Takemitsu T, et al. (2006). "Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats"

Prostaglandin EP3 receptor (4,418 words) [view diff] exact match in snippet view article find links to article

Ushikubi F, Narumiya S, Kuraishi Y (September 2005). "Involvement of cyclooxygenase-2 and EP3 prostaglandin receptor in acute herpetic but not postherpetic

SCH-58261 (865 words) [view diff] exact match in snippet view article find links to article

2007). "Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor

Allodynia (2,035 words) [view diff] no match in snippet view article find links to article

the binding is probably the production of prostaglandin E2 (PGE2) by cyclooxygenase 2 (COX-2). Activated microglia making PGE2 can then sensitize nociceptive

Prostacyclin synthase (1,212 words) [view diff] exact match in snippet view article find links to article

Xie X, Ma YT, Fu ZY, et al. (2008). "[Study on the association of cyclooxygenase-2 -765g>C and prostacyclin synthase C1117A polymorphisms and the risk

Nemosis (314 words) [view diff] exact match in snippet view article find links to article

(2004). "Cell-cell contacts trigger programmed necrosis and induce cyclooxygenase-2 expression". Cell Death and Differentiation. 11 (2): 183–195. doi:10

Swietenia macrophylla (1,503 words) [view diff] exact match in snippet view article find links to article

production of nitric oxide (NO), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumour necrosis factor-α (TNF-α) and interleukin-6 (IL-6)

Caveolin 1 (1,551 words) [view diff] exact match in snippet view article find links to article

Shyue SK, Wu KK (September 2001). "Colocalization and interaction of cyclooxygenase-2 with caveolin-1 in human fibroblasts". The Journal of Biological Chemistry

Prostacyclin (1,639 words) [view diff] exact match in snippet view article find links to article

Milne GL, Potter CM, et al. (October 2012). "Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the

Pachydermoperiostosis (3,418 words) [view diff] exact match in snippet view article find links to article

cancer and finger clubbing. This may be related to raised levels of cyclooxygenase-2, an enzyme involved in the metabolism of prostaglandins. A similar

Resolvin (1,307 words) [view diff] exact match in snippet view article find links to article

possibly 15-lipoxygenase-2 (i.e. ALOX15B), 5-lipoxygenase (i.e. ALOX5), cyclooxygenase-2 (i.e. COX-2), and certain cytochrome P450 monooxygenases. RvDs are

MST1 (901 words) [view diff] exact match in snippet view article find links to article

tyrosine kinase by macrophage-stimulating protein inhibits inducible cyclooxygenase-2 expression in murine macrophages". J. Biol. Chem. 277 (41): 38104–10

Periodontal fiber (2,806 words) [view diff] exact match in snippet view article find links to article

oxygenase-1 mediates nicotine- and lipopolysaccharide-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in human periodontal ligament cells"

Demyelinating disease (2,701 words) [view diff] exact match in snippet view article find links to article

Palumbo S, Toscano CD, Parente L, Weigert R, Bosetti F (May 2012). "The cyclooxygenase-2 pathway via the PGE₂ EP2 receptor contributes to oligodendrocytes apoptosis

Brain ischemia (2,308 words) [view diff] exact match in snippet view article find links to article

J. (1997). "Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and

Eisenia arborea (495 words) [view diff] exact match in snippet view article find links to article

Phlorotannins from Eisenia arborea Suppress Chemical Mediator Release and Cyclooxygenase-2 Signaling to Alleviate Mouse Ear Swelling". Marine Drugs. 16 (8): 267

Deferoxamine (1,477 words) [view diff] exact match in snippet view article find links to article

"Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway". Biochemical and Biophysical Research Communications

Diacylglycerol lipase (2,148 words) [view diff] exact match in snippet view article find links to article

striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG". Cell Death & Disease. 4 (10): e862.

NOX1 (883 words) [view diff] no match in snippet view article find links to article

Barbieri SS, Cavalca V, Eligini S, et al. (2005). "Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione

Hemicrania continua (1,499 words) [view diff] exact match in snippet view article find links to article

Peres MF, Silberstein SD (2002). "Hemicrania continua responds to cyclooxygenase-2 inhibitors". Headache. 42 (6): 530–1. doi:10.1046/j.1526-4610.2002

Daedalea quercina (689 words) [view diff] no match in snippet view article find links to article

mazegill, has anti-inflammatory activity, and inhibits the enzymes cyclooxygenase 2, xanthine oxidase, and horseradish peroxidase. Arora, David (1986)

Mir-26 microRNA precursor family (3,054 words) [view diff] exact match in snippet view article find links to article

He Y, Liu L, Zhong X (2010). "MiRNA-26b regulates the expression of cyclooxygenase-2 in desferrioxamine-treated CNE cells". FEBS Lett. 584 (5): 961–7. doi:10

Mechanism of action of aspirin (1,734 words) [view diff] exact match in snippet view article find links to article

acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo". Basic

Benzoylacetone (266 words) [view diff] exact match in snippet view article find links to article

"Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3-

Deguelin (667 words) [view diff] exact match in snippet view article find links to article

Hong WK, Kurie JM (February 2004). "Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells". Clin. Cancer Res.

AGPAT2 (831 words) [view diff] exact match in snippet view article find links to article

Burns AR, Pownall HJ (May 2007). "Sustained elevations in NEFA induce cyclooxygenase-2 activity and potentiate THP-1 macrophage foam cell formation". Atherosclerosis

CXCL1 (1,706 words) [view diff] exact match in snippet view article find links to article

to transcription of genes inducing chronic pain, such as c-Fos or cyclooxygenase-2 (COX-2). GRCh38: Ensembl release 89: ENSG00000163739 – Ensembl, May

TGF alpha (2,040 words) [view diff] exact match in snippet view article find links to article

Fanelli MF (Aug 2012). "The influence of transforming growth factor-α, cyclooxygenase-2, matrix metalloproteinase (MMP)-7, MMP-9 and CXCR4 proteins involved

Ketorolac (2,264 words) [view diff] exact match in snippet view article find links to article

Seo Y (March 2008). "The effects of intrathecal cyclooxygenase-1, cyclooxygenase-2, or nonselective inhibitors on pain behavior and spinal Fos-like immunoreactivity"

Joyoti Basu (1,517 words) [view diff] exact match in snippet view article find links to article

"Mycobacterium avium-induced matrix metalloproteinase-9 expression occurs in a cyclooxygenase-2-dependent manner and involves phosphorylation- and acetylation-dependent

AGPAT1 (691 words) [view diff] exact match in snippet view article find links to article

Burns AR, Pownall HJ (2007). "Sustained elevations in NEFA induce cyclooxygenase-2 activity and potentiate THP-1 macrophage foam cell formation". Atherosclerosis

Naproxcinod (1,332 words) [view diff] exact match in snippet view article find links to article

Coupal L, Zowall H (January 2005). "Treating osteoarthritis with cyclooxygenase-2-specific inhibitors: what are the benefits of avoiding blood pressure

ALOX15B (1,036 words) [view diff] exact match in snippet view article find links to article

esophageal cancer specimens and cells and upregulation in vitro by the cyclooxygenase-2 inhibitor, NS398". Neoplasia. 5 (2): 121–7. doi:10.1016/s1476-5586(03)80003-9

Primary care physician (2,550 words) [view diff] exact match in snippet view article find links to article

Stevenson JG, Bernstein SJ (2006). "Over and under-utilization of cyclooxygenase-2 selective inhibitors by primary care physicians and specialists: the

ZFP36 (1,069 words) [view diff] exact match in snippet view article find links to article

O (2003). "Tristetraprolin binds to the 3'-untranslated region of cyclooxygenase-2 mRNA. A polyadenylation variant in a cancer cell line lacks the binding

Depression (mood) (5,367 words) [view diff] exact match in snippet view article

Maino K, Kleindienst N, Möller HJ, Arolt V, Riedel M (July 2006). "The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results

Neuroprotection (3,640 words) [view diff] exact match in snippet view article find links to article

Lithium has been shown to reduce neuronal death, microglial activation, cyclooxygenase-2 induction, amyloid-β (Aβ), and hyperphosphorylated tau levels, to preserve

PPAP2A (864 words) [view diff] exact match in snippet view article find links to article

Johnson CA, Buczynski MW, Dennis EA (2006). "Lipopolysaccharide-induced cyclooxygenase-2 expression in human U937 macrophages is phosphatidic acid

Photo-reactive amino acid analog (506 words) [view diff] exact match in snippet view article find links to article

Photo-crosslinking of proteins in intact cells reveals a dimeric structure of cyclooxygenase-2 and an inhibitor-sensitive oligomeric structure of microsomal prostaglandin

Indometacin (2,297 words) [view diff] exact match in snippet view article find links to article

NSAIDs. For instance, indometacin inhibits both cyclooxygenase-1 and cyclooxygenase-2, which then inhibits the production of prostaglandins in the stomach

Osteoarthritis (13,577 words) [view diff] exact match in snippet view article find links to article

P, Barton P, Bryan S, Fry-Smith A, Harris G, et al. (April 2008). "Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam

Nabil F. Saba (1,710 words) [view diff] exact match in snippet view article find links to article

Papadimitrakopoulou VA, El-Naggar AK, Khuri FR, Chen ZG, Shin DM. "Role of cyclooxygenase-2 in tumor progression and survival of head and neck squamous cell carcinoma"

Sophoraflavanone G (1,299 words) [view diff] exact match in snippet view article find links to article

sophoraflavanone G, a prenylated flavonoid from Sophora flavescens on cyclooxygenase-2 and in vivo inflammatory response.” Archives of Pharmacal Research

Long-term impact of alcohol on the brain (2,209 words) [view diff] exact match in snippet view article find links to article

cause the upregulation of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression. The upregulation of these inflammatory mediators

Interleukin 1 beta (3,305 words) [view diff] exact match in snippet view article find links to article

cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is

TSG-6 (1,151 words) [view diff] exact match in snippet view article find links to article

Mindrescu C, Le J, Wisniewski HG, Vilcek J (May 2005). "Up-regulation of cyclooxygenase-2 expression by TSG-6 protein in macrophage cell line". Biochemical and

15-Hydroxyeicosatetraenoic acid (7,341 words) [view diff] exact match in snippet view article find links to article

Lee, S. H.; Williams, M. V.; Dubois, R. N.; Blair, I. A. (2005). "Cyclooxygenase-2-mediated DNA damage". Journal of Biological Chemistry. 280 (31): 28337–28346

Drug design (5,022 words) [view diff] no match in snippet view article find links to article

inhibitors Cannabinoid receptor antagonists CCR5 receptor antagonists Cyclooxygenase 2 inhibitors Dipeptidyl peptidase-4 inhibitors HIV protease inhibitors

Jessica Kandel (668 words) [view diff] exact match in snippet view article find links to article

Stempak D, Baruchel S, Bender JG, Kandel JJ, Yamashiro DJ. Inhibition of cyclooxygenase-2 disrupts tumor vascular mural cell recruitment and survival signaling

Apocynin (1,474 words) [view diff] no match in snippet view article find links to article

Alessia; Tremoli, Elena; Colli, Susanna (2004). "Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione

TNF inhibitor (3,827 words) [view diff] exact match in snippet view article find links to article

vitro on 15-Lipoxygenase Activity and on Lipopolysaccharide-Induced Cyclooxygenase-2 and Inflammatory Cytokines in Human U937 Macrophage Cells". Journal

TIAL1 (1,049 words) [view diff] exact match in snippet view article find links to article

Morrison AR (2003). "The proximal region of the 3'-untranslated region of cyclooxygenase-2 is recognized by a multimeric protein complex containing HuR, TIA-1

Mutagen (5,961 words) [view diff] exact match in snippet view article find links to article

ScienceDirect Topics". Lee SH, Williams MV, Dubois RN, et al. (August 2005). "Cyclooxygenase-2-mediated DNA damage". The Journal of Biological Chemistry. 280 (31):

Marathon (12,247 words) [view diff] no match in snippet view article find links to article

nonsteroidal anti-inflammatory drugs on renal function: focus on cyclooxygenase −2–selective inhibition". The American Journal of Medicine. 107 (6):

Mir-16 microRNA precursor family (4,081 words) [view diff] exact match in snippet view article find links to article

of heterogeneous nuclear ribonuclear protein K and microRNA-16 in cyclooxygenase-2 RNA stability induced by S100b, a ligand of the receptor for advanced

Fever (8,065 words) [view diff] exact match in snippet view article find links to article

relates to fever), is mediated by the enzymes phospholipase A2 (PLA2), cyclooxygenase-2 (COX-2), and prostaglandin E2 synthase. These enzymes ultimately mediate

Phlorotannin (2,750 words) [view diff] exact match in snippet view article find links to article

Phlorotannins from Eisenia arborea Suppress Chemical Mediator Release and Cyclooxygenase-2 Signaling to Alleviate Mouse Ear Swelling". Marine Drugs. 16 (8): 267

Programmed cell death (6,348 words) [view diff] exact match in snippet view article find links to article

(2004). "Cell-cell contacts trigger programmed necrosis and induce cyclooxygenase-2 expression". Cell Death and Differentiation. 11 (2): 183–195. doi:10

HPGD (1,711 words) [view diff] no match in snippet view article find links to article

557–573 (2002). Lim, H. et al. Multiple female reproductive failures in cyclooxygenase 2-defcient mice. Cell 91, 197–208 (1997). Murata, T. et al. Altered pain

Uterotonic (2,344 words) [view diff] exact match in snippet view article find links to article

eventually converted to prostaglandins by cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). Due to this mechanism, prostaglandins have a presence in many

Inflammation (9,469 words) [view diff] exact match in snippet view article find links to article

Douhe A, Cerovecki A, Goldstein-Müller B, et al. (July 2006). "The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results

L-Photo-methionine (2,542 words) [view diff] exact match in snippet view article find links to article

computationally and experimentally to help with understanding the functions. Cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) structures

Raymond Dingledine (1,743 words) [view diff] exact match in snippet view article find links to article

D; FitzGerald, GA; Dingledine, R (19 October 2011). "Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation

Diabetic nephropathy (5,134 words) [view diff] exact match in snippet view article find links to article

; Harris, Richard K.; Baron, David A. (2001-01-01). "Expression of Cyclooxygenase-2 in the Macula Densa of Human Kidney in Hypertension, Congestive Heart

Helicobacter pylori (16,255 words) [view diff] no match in snippet view article find links to article

pylori VacA enhances prostaglandin E2 production through induction of cyclooxygenase 2 expression via a p38 mitogen-activated protein kinase/activating transcription

Immunoglobulin therapy (5,507 words) [view diff] exact match in snippet view article find links to article

"Intravenous immunoglobulin expands regulatory T cells via induction of cyclooxygenase-2-dependent prostaglandin E2 in human dendritic cells". Blood. 122 (8):

Aldehyde dehydrogenase 3 family, member A1 (2,547 words) [view diff] exact match in snippet view article find links to article

"4-hydroxy-2-nonenal, the end product of lipid peroxidation, is a specific inducer of cyclooxygenase-2 gene expression". Biochem. Biophys. Res. Commun. 273 (2): 437–41. doi:10

BRAF (gene) (5,394 words) [view diff] exact match in snippet view article

by an autocrine prostaglandin E2 loop, which can be blocked using cyclooxygenase-2 (COX2) inhibitors. Notably, the simultaneous targeting of COX2 with

Cancer (20,182 words) [view diff] exact match in snippet view article find links to article

M, Moher D (March 2007). "Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors for primary prevention of colorectal cancer: a systematic

Aspirin (16,465 words) [view diff] exact match in snippet view article find links to article

Boucher M, Joyce J, et al. (July 2007). "Gastrointestinal safety of cyclooxygenase-2 inhibitors: a Cochrane Collaboration systematic review". Clinical Gastroenterology

Index of oncology articles (5,119 words) [view diff] exact match in snippet view article find links to article

breast cancer – cutaneous T-cell lymphoma – cyanogenic glucoside – cyclooxygenase-2 selective inhibitor – cyclophosphamide – cyclosporine – cyproheptadine

NF-κB (9,815 words) [view diff] exact match in snippet view article find links to article

Park HJ, Youn HS (March 2013). "Mercury induces the expression of cyclooxygenase-2 and inducible nitric oxide synthase". Toxicology and Industrial Health

Rheumatoid arthritis (17,069 words) [view diff] exact match in snippet view article find links to article

Barton P, Bryan S, Fry-Smith A, Harris G, Taylor RS (April 2008). "Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam

Chemotherapy (17,494 words) [view diff] exact match in snippet view article find links to article

adenosine, which causes immunosuppression; effects on immuno-regulatory cyclooxygenase-2 enzyme pathways; reduction in pro-inflammatory cytokines; and anti-proliferative

Recurrent cancer (2,409 words) [view diff] exact match in snippet view article find links to article

PMID 33523579. Pang, Lisa Y.; Hurst, Emma A.; Argyle, David J. (2016). "Cyclooxygenase-2: A Role in Cancer Stem Cell Survival and Repopulation of Cancer Cells

BCL3 (2,553 words) [view diff] no match in snippet view article find links to article

Greenhough A, Paraskeva C, Williams AC (May 2020). "BCL‑3 promotes cyclooxygenase‑2/prostaglandin E2 signalling in colorectal cancer". International Journal

MAPK14 (5,259 words) [view diff] no match in snippet view article find links to article

lymphocyte-specific protein1 (LSP1), cAMP response element-binding protein (CREB), cyclooxygenase 2 (COX2), activating transcription factor 1 (ATF1), serum response factor

Free statistical software (3,270 words) [view diff] exact match in snippet view article find links to article

(2007). "Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain". Genome Biol. 8 (1): R14. doi:10.1186/gb-2007-8-1-r14

Cancer prevention (4,232 words) [view diff] exact match in snippet view article find links to article

M, Moher D (March 2007). "Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors for primary prevention of colorectal cancer: a systematic

Decompression sickness (14,691 words) [view diff] exact match in snippet view article find links to article

Brune K (February 2008). "Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man". FASEB Journal. 22 (2): 383–90. doi:10.1096/fj.07-8506com

Oncolytic virus (8,503 words) [view diff] exact match in snippet view article find links to article

Wang M, Krasnykh V, Yamamoto M (June 2004). "Infectivity-enhanced cyclooxygenase-2-based conditionally replicative adenoviruses for esophageal adenocarcinoma

Sharon Hammes-Schiffer (1,969 words) [view diff] exact match in snippet view article find links to article

Roth, Justine P. (January 8, 2016). "A Revised Mechanism for Human Cyclooxygenase-2". Journal of Biological Chemistry. 291 (2): 948–958. doi:10.1074/jbc

Jon Sudbø (1,950 words) [view diff] exact match in snippet view article find links to article

W, Boysen M, Koppang HS, Reith A, Risberg B, Nesland JM, Bryne M. Cyclooxygenase-2 (COX-2) expression in high-risk premalignant oral lesions. Oral Oncol

List of 5α-reductase inhibitors (3,034 words) [view diff] exact match in snippet view article find links to article

200800125. PMID 19353546. S2CID 22807048. Oku H, Ishiguro K (2002). "Cyclooxygenase-2 inhibitory 1,4-naphthoquinones from Impatiens balsamina L." Biological

CYR61 (4,894 words) [view diff] exact match in snippet view article find links to article

motility/invasion via activation of the integrin/nuclear factor-κB/cyclooxygenase-2 signaling pathway". Clin. Cancer Res. 11 (16): 5809–5820. doi:10.1158/1078-0432

Giulio Maria Pasinetti (3,281 words) [view diff] no match in snippet view article find links to article

Aisen, Paul S.; Pasinetti, Giulio Maria (1 March 2001). "NEuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical

CYP4F2 (8,922 words) [view diff] exact match in snippet view article find links to article

Inflammatory Profile of the Tumor Microenvironment, Orchestrated by Cyclooxygenase-2, Promotes Epithelial-Mesenchymal Transition". Front Oncol. 11: 686792

HIV associated cardiomyopathy (1,953 words) [view diff] no match in snippet view article find links to article

QN, Reddy S, Sayre JW, et al. Essential role of HIV-1 infected and cyclooxygenase 2 activated macrophages and T cells in HIV type 1 myocarditis. AIDS Res

HPG80 (5,038 words) [view diff] exact match in snippet view article find links to article

ISSN 0007-1323. PMID 10931047. S2CID 24292877. DuBois, Raymond N. (2009), "Cyclooxygenase-2 in Colorectal Cancer", Encyclopedia of Cancer, Berlin, Heidelberg:

Th 9 cell (3,209 words) [view diff] exact match in snippet view article find links to article

Artiom; Cheng, Jennifer; Dackor, Ryan T.; Wang, Ping Ming (2013-04-15). "Cyclooxygenase-2 Inhibits T Helper Cell Type 9 Differentiation during Allergic Lung

Shuji Ogino (4,054 words) [view diff] exact match in snippet view article find links to article

CS (2007). "Aspirin use and risk of colorectal cancer according to cyclooxygenase-2 expression". N Engl J Med. 356 (21): 2131–42. doi:10.1056/nejmoa067208

Testicular immunology (6,116 words) [view diff] exact match in snippet view article find links to article

nitric oxide (NO), transforming growth factor beta (TGFβ), the enzyme cyclooxygenase-2 (COX-2) and its product prostaglandin E2, and many others. Further

Alex Bekker (1,750 words) [view diff] exact match in snippet view article find links to article

Lebovits, A. (2002). Evaluation of Preoperative Administration of the Cyclooxygenase-2 Inhibitor Rofecoxib for the Treatment of Postoperative Pain after Lumbar

Treatment of lung cancer (6,487 words) [view diff] exact match in snippet view article find links to article

JM; Mao JT; Krysan K; Dubinett SM (April 2007). "Significance of cyclooxygenase-2 in prognosis, targeted therapy and chemoprevention of NSCLC". Future

Nicolas Bazan (4,361 words) [view diff] exact match in snippet view article find links to article

PAF activates transcription of the inducible prostaglandin synthase, cyclooxygenase-2 (COX-2). Subsequently, the Bazan laboratory demonstrated that secretory

Central nervous system effects from radiation exposure during spaceflight (9,521 words) [view diff] exact match in snippet view article find links to article

JC; Williams, JP; Hansen, JT; Kerry O'Banion, M (15 August 2002). "Cyclooxygenase-2 modulates brain inflammation-related gene expression in central nervous

N-Acylethanolamine (20,234 words) [view diff] exact match in snippet view article find links to article

1997). "Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2". The Journal of Biological Chemistry. 272 (34): 21181–6. doi:10.1074/jbc

Xanthatin (1,885 words) [view diff] exact match in snippet view article find links to article

of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression by xanthanolides isolated from Xanthium strumarium". Bioorganic

List of Vanderbilt University people (30,869 words) [view diff] exact match in snippet view article find links to article

V.; Marnett, Lawrence J.; Nigam, Santosh; Dennis, Edward (eds.), "Cyclooxygenase-2 In Human Pathological Disease", Eicosanoids and Other Bioactive Lipids

Brain health and pollution (6,918 words) [view diff] exact match in snippet view article find links to article

increased neuro-inflammation and vascular damage: upregulated mRNA cyclooxygenase-2, interleukin-1β and CD14, and clusters of mononuclear cells around