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Find link is a tool written by Edward Betts.Longer titles found: Lanosterol 14 alpha-demethylase (view), Cytochrome P450 aromatic O-demethylase (view), Sterol 14-demethylase (view), (Histone-H3)-lysine-36 demethylase (view), Thebaine 6-O-demethylase (view), Codeine 3-O-demethylase (view), Histone demethylase (view), 7-Methylxanthine demethylase (view), DNA oxidative demethylase (view), AlkB homolog 5, RNA demethylase (view)
searching for Demethylase 176 found (244 total)
alternate case: demethylase
Oxiconazole
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Oxiconazole (trade names Oxistat in the US, Oxizole in Canada) is an antifungal medication typically administered in a cream or lotion to treat skin infectionsMiconazole (1,056 words) [view diff] exact match in snippet view article find links to article
hypoglycaemia (low blood sugar) Miconazole inhibits the fungal enzyme 14α-sterol demethylase, resulting in a reduced production of ergosterol. In addition to itsButoconazole (97 words) [view diff] no match in snippet view article find links to article
Butoconazole (trade names Gynazole-1, Mycelex-3) is an imidazole antifungal used in gynecology. It is administered as a vaginal cream. Seidman LS, SkokosCroconazole (61 words) [view diff] no match in snippet view article find links to article
Croconazole (INN) is an imidazole antifungal. Pfaller MA (2010). "Chapter 143: Croconazole". In Turner A (ed.). Logan Turner's Diseases of the Nose, ThroatTioconazole (242 words) [view diff] no match in snippet view article find links to article
Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand namesKDM3B (650 words) [view diff] exact match in snippet view article find links to article
Lysine-specific demethylase 3B is an enzyme that in humans is encoded by the KDM3B gene. KDM3B belongs to the alpha-ketoglutarate-dependent hydroxylaseKDM5D (1,083 words) [view diff] exact match in snippet view article find links to article
Lysine-specific demethylase 5D is an enzyme that in humans is encoded by the KDM5D gene. KDM5D belongs to the alpha-ketoglutarate-dependent hydroxylasesBifonazole (322 words) [view diff] no match in snippet view article find links to article
Bifonazole (trade name Canespor among others) is an imidazole antifungal drug used in form of ointments. It was patented in 1974 and approved for medicalKDM1A (2,086 words) [view diff] exact match in snippet view article find links to article
Lysine-specific histone demethylase 1A (LSD1) also known as lysine (K)-specific demethylase 1A (KDM1A) is a protein that in humans is encoded by the KDM1AOmoconazole (100 words) [view diff] no match in snippet view article find links to article
Omoconazole is an azole antifungal drug. Omonocazole is not available in the United States and Canada. In other countries, it is used to treat cutaneousLuliconazole (125 words) [view diff] no match in snippet view article find links to article
Luliconazole, trade names Luzu among others, is an imidazole antifungal medication. As a 1% topical cream, It is indicated for the treatment of athlete'sChlormidazole (55 words) [view diff] no match in snippet view article find links to article
Chlormidazole (INN, also known as clomidazole) is used as a spasmolytic and azole antifungal drug. Clemizole Krasiejko I, Gajewicz L, Lipnicki D (1990)Fenticonazole (359 words) [view diff] no match in snippet view article find links to article
Fenticonazole is an imidazole antifungal drug, used locally as the nitrate in the treatment of vulvovaginal candidiasis. It is active against a range ofKDM5C (855 words) [view diff] exact match in snippet view article find links to article
Lysine-specific demethylase 5C is an enzyme that in humans is encoded by the KDM5C gene. KDM5C belongs to the alpha-ketoglutarate-dependent hydroxylaseEberconazole (194 words) [view diff] no match in snippet view article find links to article
Eberconazole is an antifungal drug. As a 1% topical cream, it is an effective treatment for dermatophytosis, candidiasis, and pityriasis. It was approvedEconazole (405 words) [view diff] no match in snippet view article find links to article
Econazole is an antifungal medication of the imidazole class. It was patented in 1968, and approved for medical use in 1974. Econazole is used as a creamSulconazole (132 words) [view diff] no match in snippet view article find links to article
Sulconazole (trade name Exelderm) is an antifungal medication of the imidazole class. It is available as a cream or solution to treat skin infections suchBisantrene (1,798 words) [view diff] exact match in snippet view article find links to article
which is a m6A RNA demethylase. The same study found that bisantrene is a weak inhibitor of ALKBH5, which is the only other demethylase, i.e. bisantreneSertaconazole (570 words) [view diff] exact match in snippet view article find links to article
sertaconazole blocks the synthesis of ergosterol by inhibiting the 14α-demethylase enzyme. Ergosterol is a critical component of the fungal cell membraneFluconazole (2,821 words) [view diff] exact match in snippet view article find links to article
cytochrome P450 enzyme 14α-demethylase. Mammalian demethylase activity is much less sensitive to fluconazole than fungal demethylase. This inhibition preventsFosfluconazole (205 words) [view diff] no match in snippet view article find links to article
Fosfluconazole (INNTooltip International Nonproprietary Name) is a water-soluble phosphate prodrug of fluconazole — a triazole antifungal drug used inIsoconazole (218 words) [view diff] no match in snippet view article find links to article
Isoconazole is an azole antifungal drug and could inhibit gram positive bacteria. For foot and vaginal infections, isoconazole has a similar effectivenessVoriconazole (1,125 words) [view diff] no match in snippet view article find links to article
Voriconazole, sold under the brand name Vfend among others, is an antifungal medication used to treat a number of fungal infections. This includes aspergillosisAlbaconazole (98 words) [view diff] no match in snippet view article find links to article
Albaconazole (development code UR-9825) is an experimental triazole antifungal. It has potential broad-spectrum activity. The drug blocks a number of CYP450Neticonazole (118 words) [view diff] no match in snippet view article find links to article
Neticonazole (INN) is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is only approved for use in Japan. It is sold asRavuconazole (182 words) [view diff] no match in snippet view article find links to article
Ravuconazole (codenamed BMS-207147 and ER-30346) is a potent triazole antifungal, the development of which was discontinued in 2007. The drug has shownClotrimazole (1,422 words) [view diff] exact match in snippet view article find links to article
fungal cell membrane, by inhibiting the P450 enzyme lanosterol 14-alpha demethylase. Clotrimazole may slow fungal growth or result in fungal cell death.Hexaconazole (78 words) [view diff] no match in snippet view article find links to article
Hexaconazole is a broad-spectrum systemic triazole fungicide used for the control of many fungi particularly Ascomycetes and Basidiomycetes. Major consumptionEnilconazole (575 words) [view diff] no match in snippet view article find links to article
Enilconazole (synonyms imazalil, chloramizole) is a fungicide widely used in agriculture, particularly in the growing of citrus fruits. Trade names includeTerconazole (1,964 words) [view diff] no match in snippet view article find links to article
Terconazole is an antifungal drug used to treat vaginal yeast infection. It comes as a lotion or a suppository and disrupts the biosynthesis of fats inIsavuconazonium (1,255 words) [view diff] exact match in snippet view article find links to article
isavuconazole. Isavuconazole works by inhibition of lanosterol 14α-demethylase, the enzyme responsible for converting lanosterol to ergosterol by demethylationTebuconazole (198 words) [view diff] no match in snippet view article find links to article
Tebuconazole is a triazole fungicide used agriculturally to treat plant pathogenic fungi. Though the U.S. Food and Drug Administration considers this fungicideLevoketoconazole (432 words) [view diff] exact match in snippet view article find links to article
(cholesterol side-chain cleavage enzyme) and CYP51A1 (lanosterol-14α-demethylase), similarly but more potently relative to ketoconazole. "FDA-sourcedFTO gene (3,884 words) [view diff] exact match in snippet view article find links to article
16. As one homolog in the AlkB family proteins, it is the first mRNA demethylase that has been identified. Certain alleles of the FTO gene appear to beUTX (gene) (823 words) [view diff] exact match in snippet view article
Lysine-specific demethylase 6A also known as Ubiquitously transcribed tetratricopeptide repeat, X chromosome (UTX), is a protein which in humans is encodedKetoconazole (4,374 words) [view diff] exact match in snippet view article find links to article
ketoconazole works principally by inhibiting the enzyme cytochrome P450 14α-demethylase (CYP51A1). This enzyme participates in the sterol biosynthesis pathwayPramiconazole (58 words) [view diff] no match in snippet view article find links to article
Pramiconazole is a triazole antifungal which was under development by Barrier Therapeutics for the treatment of acute skin and mucosal fungal infectionsKDM4D (410 words) [view diff] exact match in snippet view article find links to article
Lysine-specific demethylase 4D is an enzyme that in humans is encoded by the KDM4D gene. KDM4D belongs to the alpha-ketoglutarate-dependent hydroxylaseHR (gene) (1,145 words) [view diff] exact match in snippet view article
MUHH, MUHH1, hair growth associated, lysine demethylase and nuclear receptor corepressor, HR lysine demethylase and nuclear receptor corepressor ExternalKDM4B (593 words) [view diff] exact match in snippet view article find links to article
Lysine-specific demethylase 4B is an enzyme that in humans is encoded by the KDM4B gene. KDM4B belongs to the alpha-ketoglutarate-dependent hydroxylaseEconazole/triamcinolone (71 words) [view diff] no match in snippet view article find links to article
Econazole/triamcinolone is a combination drug, consisting of econazole (an imidazole antifungal) and triamcinolone (a group III topical steroid). It isKDM2B (1,477 words) [view diff] exact match in snippet view article find links to article
The human KDM2B gene encodes the protein lysine (K)-specific demethylase 2B. KDM2B is broadly and highly expressed in embryonic tissues (especially inUniconazole (293 words) [view diff] no match in snippet view article find links to article
Uniconazole is a triazole chemical used as a plant growth retardant. It is active on a wide range of plants and acts by inhibiting the production of gibberellinsSarcosine dehydrogenase (1,589 words) [view diff] exact match in snippet view article find links to article
oxidoreductase (demethylating). Other names in common use include sarcosine N-demethylase, monomethylglycine dehydrogenase, and sarcosine:(acceptor) oxidoreductaseN-methyl-L-amino-acid oxidase (192 words) [view diff] exact match in snippet view article find links to article
and demethylase. Moritani M (1952). "Demethylase. IV. Kinetics and reaction mechanism". Hukuoka Acta Med. 43: 651–658. Moritani M (1952). "Demethylase. VVanillate monooxygenase (195 words) [view diff] exact match in snippet view article find links to article
names in common use include 4-hydroxy-3-methoxybenzoate demethylase, and vanillate demethylase. This enzyme participates in 2,4-dichlorobenzoate degradationUTY (gene) (683 words) [view diff] exact match in snippet view article
Histone demethylase UTY is an enzyme that in humans is encoded by the UTY gene. This gene encodes a protein containing tetratricopeptide repeats whichKDM7A (140 words) [view diff] exact match in snippet view article find links to article
Lysine demethylase 7A is a protein that in humans is encoded by the KDM7A gene. GRCh38: Ensembl release 89: ENSG00000006459 – Ensembl, May 2017 GRCm38:Dihydrolanosterol (124 words) [view diff] exact match in snippet view article find links to article
sterol 14alpha-demethylase. Lanosterol Obtusifoliol Cycloartenol Lepesheva, GI; Waterman, MR (March 2007). "Sterol 14alpha-demethylase cytochrome P450KDM3A (229 words) [view diff] exact match in snippet view article find links to article
Lysine demethylase 3A is a protein that in humans is encoded by the KDM3A gene. This gene encodes a zinc finger protein that contains a jumonji C (JmjC)Cyproconazole (1,208 words) [view diff] no match in snippet view article find links to article
Cyproconazole is an agricultural fungicide of the class of azoles, used on cereal crops, coffee, sugar beet, fruit trees and grapes, on sod farms and golfH-Y antigen (664 words) [view diff] exact match in snippet view article find links to article
later identified as an 11-residue peptide from the Lysine-Specific Demethylase 5D protein (KDM5D gene) presented by HLA-B7. A third example is MEA1Beta-Sitosterol (1,397 words) [view diff] exact match in snippet view article find links to article
sterol C-14 demethylase (E4), sterol Δ14-reductase (E5), and sterol Δ8-Δ7-isomerase (E6). The last methyl group is removed by sterol demethylase (E7) to formEburicol (78 words) [view diff] exact match in snippet view article find links to article
sterol 14alpha-demethylase ERG11. Aoyama, Y; Yoshida, Y (15 August 1991). "Different substrate specificities of lanosterol 14a-demethylase (P-45014DM) ofMiR-137 (2,115 words) [view diff] exact match in snippet view article find links to article
miRecords database. Among these targets, LSD1 (Lysine-specific histone demethylase 1A, also known as KDM1A) has been shown to be directly downregulatedX-linked intellectual disability (1,927 words) [view diff] exact match in snippet view article find links to article
X-linked intellectual disability and epilepsy. KDM5C: Lysine-specific demethylase 5C is an enzyme that in humans is encoded by the KDM5C gene a memberSteroidogenesis inhibitor (2,107 words) [view diff] exact match in snippet view article find links to article
are currently under investigation for such indications. Lanosterol 14α-demethylase (CYP51A1) inhibitors such as clotrimazole, fluconazole, itraconazoleTrimethylamine-oxide aldolase (141 words) [view diff] exact match in snippet view article find links to article
formaldehyde-lyase, trimethylamine N-oxide aldolase, trimethylamine N-oxide demethylase, and trimethylamine-N-oxide formaldehyde-lyase. This enzyme participatesN6-methyl-lysine oxidase (149 words) [view diff] exact match in snippet view article find links to article
oxidoreductase, N6-methyllysine oxidase, epsilon-N-methyllysine demethylase, epsilon-alkyllysinase, and 6-N-methyl-L-lysine:oxygen oxidoreductaseAntifungal (2,564 words) [view diff] exact match in snippet view article find links to article
conversion of lanosterol to ergosterol by inhibition of lanosterol 14α-demethylase. These compounds have a five-membered ring containing two or three nitrogenAlkb homolog 1, histone h2a dioxygenase (583 words) [view diff] exact match in snippet view article find links to article
Seeberg E, Krokan HE (February 2003). "Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA". Nature. 421 (6925): 859–63Obtusifoliol (77 words) [view diff] exact match in snippet view article find links to article
2011). "Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans". Archives of Biochemistry and BiophysicsRIOX2 (575 words) [view diff] exact match in snippet view article find links to article
histone demethylase activity identical protein binding histone H3-methyl-lysine-4 demethylase activity histone H3-methyl-lysine-36 demethylase activityAlkb homolog 1, histone h2a dioxygenase (583 words) [view diff] exact match in snippet view article find links to article
Seeberg E, Krokan HE (February 2003). "Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA". Nature. 421 (6925): 859–63JARID2 (1,133 words) [view diff] exact match in snippet view article find links to article
regulatory region sequence-specific DNA binding chromatin binding histone demethylase activity DNA-binding transcription repressor activity, RNA polymeraseOxidoreductase NAD-binding domain (222 words) [view diff] exact match in snippet view article find links to article
nitrate reductase from plants, nitric-oxide synthase, bacterial vanillate demethylase and others. Xanthine dehydrogenases, that also bind FAD/NAD, have essentiallyN-Nitrosonornicotine (988 words) [view diff] exact match in snippet view article find links to article
of the stomach. Nicotine is converted into nornicotine via nicotine N-demethylase (NND), an enzyme found in the tobacco plant that works by removing theRIOX1 (152 words) [view diff] exact match in snippet view article find links to article
metal ion binding histone H3-methyl-lysine-4 demethylase activity histone H3-methyl-lysine-36 demethylase activity 2-oxoglutarate-dependent dioxygenasePotyviridae (806 words) [view diff] exact match in snippet view article find links to article
Wang, Haijuan; Pasin, Fabio; Zhao, Mingmin (October 2022). "AlkB RNA demethylase homologues and N6 -methyladenosine are involved in Potyvirus infection"Methyl-CpG-binding domain protein 2 (1,442 words) [view diff] exact match in snippet view article find links to article
Ramchandani S, Cervoni N, Szyf M (1999). "A mammalian protein with specific demethylase activity for mCpG DNA". Nature. 397 (6720): 579–83. Bibcode:1999NaturPHF2 (205 words) [view diff] exact match in snippet view article find links to article
ontology Molecular function iron ion binding histone H3-methyl-lysine-9 demethylase activity transcription coactivator activity dioxygenase activity metalSHOX2 (696 words) [view diff] exact match in snippet view article find links to article
(2009). "The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor". BMB Rep. 42 (3):UTY (60 words) [view diff] exact match in snippet view article find links to article
Japanese broadcast network affiliated with the JNN UTY (gene), histone demethylase UTY, enzyme that in humans is encoded by the UTY gene This disambiguationLi Zhang (biologist) (946 words) [view diff] exact match in snippet view article
proteins; Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family; Heme: A versatile signalingEthylmorphine (445 words) [view diff] exact match in snippet view article find links to article
PMID 9547411. Amacher DE, Schomaker SJ (January 1998). "Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepaticChromosome 16 (1,672 words) [view diff] exact match in snippet view article find links to article
ITFG3: encoding protein Protein ITFG3 KDM8: encoding protein Lysine demethylase 8 KIAA0895L: uncharacterized protein KIAA0895-like LINC00273 encodingBomedemstat (1,085 words) [view diff] exact match in snippet view article find links to article
Bomedemstat was developed to inhibit the human enzyme lysine-specific demethylase-1 (LSD1 or KDM1A EC:1.14.99.66), an oxidating enzyme that mediates demethylationPHF21A (554 words) [view diff] exact match in snippet view article find links to article
C, Lan F, Iwase S, Baba T, Shi Y (2005). "Regulation of LSD1 histone demethylase activity by its associated factors". Mol. Cell. 19 (6): 857–64. doi:10Pisatin (1,370 words) [view diff] exact match in snippet view article find links to article
shown to reduce the toxicity of the molecule. An enzyme known as pisatin demethylase is responsible for this catalysis and has been identified in N. haematococcaList of cytochrome P450 modulators (78 words) [view diff] exact match in snippet view article find links to article
(25-hydroxyvitamin D3 1α-hydroxylase) CYP39A1 (oxysterol 7α-hydroxylase 2) CYP46A1 (cholesterol 24-hydroxylase) CYP51A1 (lanosterol 14α-demethylase)Fungicide (1,357 words) [view diff] exact match in snippet view article find links to article
Management Science 56:833–841 Schnabel, G., and Jones, A. L. 2001. The 14a-demethylase (CYP51A1) gene is overexpressed in V. inaequalis strains resistant toChromosome 11 (1,930 words) [view diff] exact match in snippet view article find links to article
encoding protein IGF2 antisense RNA INS: insulin gene KDM2A: lysine demethylase 2A KIAA1549L encoding protein KIAA1549-like KRTAP5-6: encoding protein4,4'-Dihydroxybenzophenone (203 words) [view diff] exact match in snippet view article find links to article
4′-dihydroxybenzophenone mimicking sterol substrate in the active site of sterol 14α-demethylase (CYP51)". Journal of Biological Chemistry. 283 (22): 15152–15159. doi:10Temperature-dependent sex determination (3,823 words) [view diff] exact match in snippet view article find links to article
and American researchers showed that the histone H3 lysine 27 (H3K27) demethylase KDM6B (JMJD3), an epigenetic modifier, activates male development inSALL4 (4,631 words) [view diff] exact match in snippet view article find links to article
to bind to other epigenetic modifiers such as histone lysine-specific demethylase 1 (LSD1), which is frequently associated with the NuRD complex and subsequentlyX-linked recessive inheritance (1,754 words) [view diff] exact match in snippet view article find links to article
disability and facial dysmorphism, caused by mutations in the histone demethylase PHF8 Simpson–Golabi–Behmel syndrome; coarse faces with protruding jawChromosome 12 (1,735 words) [view diff] exact match in snippet view article find links to article
subfamily A member 1 at 12p13.32 KDM2B: encoding protein Lysine (K)-specific demethylase 2B KERA: keratocan KRAS: V-Ki-ras2 Kirsten rat sarcoma viral oncogeneCheb (disambiguation) (151 words) [view diff] exact match in snippet view article
Algerian raï musician Cheb (musician), Moroccan musician CheB, is a demethylase of methyl-accepting chemotaxis proteins (MCP) This disambiguation pagePatrik Rorsman (950 words) [view diff] exact match in snippet view article find links to article
Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science. 318 (5855): 1469–1472. Bibcode:2007Sci...318.1469G. doi:10Ruegeria pomeroyi (1,097 words) [view diff] exact match in snippet view article find links to article
Whitman, William B. (2008-12-01). "Dimethylsulfoniopropionate-dependent demethylase (DmdA) from Pelagibacter ubique and Silicibacter pomeroyi". Journal ofTomas Lindahl (1,310 words) [view diff] exact match in snippet view article find links to article
Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science. 318 (5855): 1469–1472. Bibcode:2007Sci...318.1469G. doi:10MMACHC (1,111 words) [view diff] exact match in snippet view article find links to article
ontology Molecular function cobalamin binding protein binding FAD binding demethylase activity protein homodimerization activity glutathione binding cyanocobalaminChromosome 7 (2,947 words) [view diff] exact match in snippet view article find links to article
IQCE: IQ domain-containing protein E KDM7A: encoding protein Lysine demethylase 7A LCHN: protein encoded by the KIAA1147 gene LHFPL3: LHFPL tetraspanPELP-1 (3,909 words) [view diff] exact match in snippet view article find links to article
including CBP/p300, histone deacetylase 2, histones, SUMO2, lysine-specific demethylase 1 (KDM1), PRMT6, and CARM1. PELP1 also interacts with cell cycle regulatorsPseudomonas putida (1,454 words) [view diff] exact match in snippet view article find links to article
M (2011). "Characterization of a broad-specificity non-haem iron N-demethylase from Pseudomonas putida CBB5 capable of utilizing several purine alkaloidsCunninghamella elegans (3,012 words) [view diff] exact match in snippet view article find links to article
and by phenanthrene. C. elegans also possesses a lanosterol 14-alpha demethylase, another enzyme in the cytochrome P450 family. Cunninghamella elegansTyphula incarnata (891 words) [view diff] exact match in snippet view article find links to article
permanent or when snow begins to melt. Mixtures of fungicides, such as a demethylase inhibitor (DMI) with a chlorothalonil product or thiophanate-methyl productTranylcypromine (2,455 words) [view diff] exact match in snippet view article find links to article
release. Tranylcypromine has also been shown to inhibit the histone demethylase, BHC110/LSD1. Tranylcypromine inhibits this enzyme with an IC50 < 2 μMH3K4me1 (1,611 words) [view diff] exact match in snippet view article find links to article
cell specific gene regulation. Suppression of the H3K4 mono- and di-demethylase LSD-1 might extend lifespan in various species. H3K4me allows bindingWithaferin A (764 words) [view diff] exact match in snippet view article find links to article
cycloartenol synthase (CAS), sterol methyl transferase (SMT), obtusifoliol-14 –demethylase (ODM). To produce withaferin A from 24-methylene cholesterol, the moleculeARID5B (641 words) [view diff] exact match in snippet view article find links to article
transcription repressor activity, RNA polymerase II-specific histone demethylase activity DNA-binding transcription factor activity, RNA polymerase II-specificMary Beckerle (1,653 words) [view diff] exact match in snippet view article find links to article
is focused on an essential regulating protein called lysine specific demethylase (LSD1). Preliminary research has aimed to halt the function of LSD1 toNorcycloartenol (302 words) [view diff] exact match in snippet view article find links to article
requirements for substrate recognition of Mycobacterium tuberculosis 14 alpha-demethylase: implications for sterol biosynthesis". Journal of Lipid Research. 4229-Norlanosterol (116 words) [view diff] exact match in snippet view article find links to article
obtusifoliol 14 alpha-demethylase of Sorghum bicolor (L.) Moench, a cytochrome P450 orthologous to the sterol 14 alpha-demethylases (CYP51) from fungi andPCGF6 (618 words) [view diff] exact match in snippet view article find links to article
Shiekhattar R (2007). "Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein". Cell. 128 (5): 877–87. doi:10Hypothenemus hampei (1,465 words) [view diff] exact match in snippet view article find links to article
consists of ca. 163 million base pairs (Vega et al. 2015 [3]. Caffeine demethylase has been shown to be responsible for caffeine breakdown in the alimentaryCleft lip and cleft palate (10,403 words) [view diff] exact match in snippet view article find links to article
gene PHF8. The research found that PHF8 encodes for a histone lysine demethylase, and is involved in epigenetic regulation. The catalytic activity ofViridin (728 words) [view diff] exact match in snippet view article find links to article
the C-14 methyl group is lost as formic acid by action of sterol 14-demethylase. Though the C-13 methyl group isn't removed in the pathway of aldosteroneVestigial-like family member 3 (422 words) [view diff] exact match in snippet view article find links to article
2009). "The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor" (PDF). BMB ReportsCNOT4 (572 words) [view diff] exact match in snippet view article find links to article
Fingerman IM, South PF, Briggs SD (April 2009). "Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression". Genes & DevelopmentBiomarkers of aging (2,507 words) [view diff] exact match in snippet view article find links to article
experienced by the organism as it develops and ages. UTX-1, a H3K27me3 demethylase, plays a critical role in the aging of C.elegans: increased utx-1 expressionPhilip Kantoff (968 words) [view diff] exact match in snippet view article find links to article
inhibition controls aggressive prostate tumors deficient in Y-linked histone demethylase KDM5D". The Journal of Clinical Investigation. 128 (7): 2979–2995. doi:10Dicamba (3,109 words) [view diff] exact match in snippet view article find links to article
first breakdown step comprise a three-component system called dicamba O-demethylase. In the 2000s, Monsanto incorporated one component of the three enzymesUnspecific monooxygenase (909 words) [view diff] exact match in snippet view article find links to article
K, Takahashi K, Katagiri M (1988). "Aromatase and nonaromatizing 10-demethylase activity of adrenal cortex mitochondrial P-450(11)beta". Arch. BiochemKMT2D (3,946 words) [view diff] exact match in snippet view article find links to article
domain-containing fragments of human KMT2C and KMT2D. UTX, the complex’s H3K27 demethylase, PTIP, and PA1 are subunits that are unique to KMT2C and KMT2D. KMT2DCACUL1 (483 words) [view diff] exact match in snippet view article find links to article
regulation of ERα by a novel protein CAC1 through association with histone demethylase LSD1". FEBS Lett. 587 (1): 17–22. doi:10.1016/j.febslet.2012.10.054.FBXL4 (627 words) [view diff] exact match in snippet view article find links to article
leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein". The JournalH3K4me3 (2,323 words) [view diff] exact match in snippet view article find links to article
Clouaire T, Aguirrebengoa M, Legube G, Miller KM (July 2017). "Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair"Stephen O'Rahilly (1,646 words) [view diff] exact match in snippet view article find links to article
Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science. 318 (5855): 1469–1472. Bibcode:2007Sci...318.1469G. doi:10Gerry Wright (450 words) [view diff] exact match in snippet view article find links to article
Biochemistry Institutions McMaster University Thesis Investigation of the lanosterol 14[alpha]-demethylase (P-45014DM) from Saccharomyces cerevisiae (1990)Set domain containing 1b (353 words) [view diff] exact match in snippet view article find links to article
atypical 12q24.31 microdeletion implicates six genes including a histone demethylase KDM2B and a histone methyltransferase SETD1B in syndromic intellectualHypoxia-inducible factor (4,911 words) [view diff] exact match in snippet view article find links to article
Ringel AE, Booker MA, Tolstorukov MY, et al. (March 2019). "Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate". ScienceCellular differentiation (6,014 words) [view diff] exact match in snippet view article find links to article
(ESC) genes, and the activation of cell fate genes. Lysine specific demethylase 1 (KDM1A) is thought to prevent the use of enhancer regions of pluripotencyFHL2 (5,030 words) [view diff] exact match in snippet view article find links to article
(Dec 2006). "Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancerMothers against decapentaplegic homolog 3 (4,177 words) [view diff] exact match in snippet view article find links to article
Janknecht R (February 2008). "Repression of Smad3 activity by histone demethylase SMCX/JARID1C". Biochemical and Biophysical Research Communications. 366Xp11.2 duplication (3,270 words) [view diff] exact match in snippet view article find links to article
or refuting this possibility remains absent. KDM5C (Lysine-Specific Demethylase 5C) also known as jumonji, A/T-rich interactive domain 1C (JARID1C) isY chromosome (8,086 words) [view diff] exact match in snippet view article find links to article
USP9Y USP9X Ubiquitin protease. DDX3Y DDX3X Helicase. UTY UTX Histone demethylase. TB4Y TB4X AZFb (none) Second AZF region on arm q. Prone to NAHR [non-allelicChris Ponting (1,832 words) [view diff] exact match in snippet view article find links to article
Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science. 318 (5855): 1469–1472. Bibcode:2007Sci...318.1469G. doi:10TMEM242 (1,522 words) [view diff] exact match in snippet view article find links to article
notable transcription factor is the Retinoblastoma-binding protein with demethylase activity. There are ubiquitous basal level expression of tmem242 in allRepressilator (2,190 words) [view diff] exact match in snippet view article find links to article
Evening-phased transcription factor CCA1 Hiking Expedition (CHE) and histone demethylase jumonji C domain-containing 5 (JMJD5) directly repress CCA1. Other componentsAzoospermia factor (1,143 words) [view diff] exact match in snippet view article find links to article
Eukaryotic Translation Initiation Factor 1A, Y-linked (EIF1AY), Lysine Demethylase 5D (KDM5D), X Linked Kell Blood Group Precursor, Y-linked (XKRY), andChuan He (1,145 words) [view diff] exact match in snippet view article find links to article
regulatory roles. He and colleagues subsequently discovered the first RNA demethylase that oxidatively reverses N6-methyladenosine (m6A) methylation in mammalianPaclobutrazol (2,246 words) [view diff] exact match in snippet view article find links to article
is a better fit to the active site of the fungal cytochrome P450 14α-demethylase. This inhibits the conversion of lanosterol to ergosterol, a componentAcute myeloid leukemia (7,040 words) [view diff] exact match in snippet view article find links to article
likely in the early stages of AML. Such mutations include in the DNA demethylase TET2 and the metabolic enzymes IDH1 and IDH2, which lead to the generationSadaf Farooqi (1,303 words) [view diff] exact match in snippet view article find links to article
Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science. 318 (5855): 1469–1472. Bibcode:2007Sci...318.1469G. doi:10Jian-Kang Zhu (2,374 words) [view diff] exact match in snippet view article find links to article
5-methylcytosine DNA glycosylase/lyase ROS1 in 2002. ROS1 is the first DNA demethylase (the enzyme initiating active DNA demethylation) established with geneticAlfred G. Gilman (3,668 words) [view diff] exact match in snippet view article find links to article
ISBN 978-1-4381080-70. Gilman, AG; Conney, AH (1963). "The induction of aminoazo dye N-demethylase in nonhepatic tissues by 3-methylcholanthrene". Biochemical PharmacologyDNA oxidation (4,790 words) [view diff] exact match in snippet view article find links to article
promoter regions. Perillo et al., showed that the lysine-specific histone demethylase LSD1 generates a local burst of reactive oxygen species (ROS) that inducesAlkb homolog 3, alpha-ketoglutaratedependent dioxygenase (615 words) [view diff] exact match in snippet view article find links to article
activity 2-oxoglutarate-dependent dioxygenase activity cytosine C-5 DNA demethylase activity Cellular component nucleus mitochondrion nucleoplasm cytoplasmList of EC numbers (EC 2) (21,664 words) [view diff] exact match in snippet view article
(cytosine32-N3)-methyltransferase EC 2.1.1.269: dimethylsulfoniopropionate demethylase EC 2.1.1.270: (+)-6a-hydroxymaackiain 3-O-methyltransferase EC 2.1.1C7orf25 (683 words) [view diff] exact match in snippet view article find links to article
of transcription 409 427 - RBP2 Retinoblastoma-binding proteins with demethylase activity 538 546 - YY1F Activator/repressor binding to transcriptionMarjorie Bick (2,424 words) [view diff] exact match in snippet view article find links to article
L (1972). "The inductive effect of piperonyl butoxide on microsomal demethylase activity". Science of the Total Environment. 1 (2): 197–203. Bibcode:1972ScTEnList of MeSH codes (D08) (15,232 words) [view diff] exact match in snippet view article
oxidoreductases, n-demethylating MeSH D08.811.682.662.582.276 – aminopyrine n-demethylase MeSH D08.811.682.662.582.338 – cytochrome p-450 cyp2e1 MeSH D08.811.682Zebrafish (11,535 words) [view diff] exact match in snippet view article find links to article
Stewart S, Tsun ZY, Izpisua Belmonte JC (November 2009). "A histone demethylase is necessary for regeneration in zebrafish". Proceedings of the NationalSónia Rocha (1,435 words) [view diff] exact match in snippet view article find links to article
MC, Beroukhim R, Signoretti S, Koivunen P, Kaelin WG (2019). "Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate". ScienceAOC3 (3,002 words) [view diff] exact match in snippet view article find links to article
copper dependent class of amine oxidases, such as lysyl oxidase or lysine demethylase, and is one of the four known in humans. The other class is flavin dependentFGFR1OP2 (1,126 words) [view diff] exact match in snippet view article find links to article
endothelial growth 0.923 + acaCACGcact RBP2 Retinoblastoma-binding protein 2 Demethylase 1.000 + GCACagcgc PLAG1 Pleomorphic adenoma gene 1 Cell proliferationCancer epigenetics (12,530 words) [view diff] exact match in snippet view article find links to article
their corresponding enzymes. Several histone methyltransferases and demethylases are among these enzymes. Prostate cancer kills around 35,000 men yearlyH3K9me2 (2,601 words) [view diff] exact match in snippet view article find links to article
and PRDM2. H3K9me2 can be removed by a wide range of histone lysine demethylases (KDMs) including KDM1, KDM3, KDM4 and KDM7 family members. H3K9me2 isEpigenetics in forensic science (1,686 words) [view diff] exact match in snippet view article find links to article
and quite a few affect the epigenome. For example, JMJD3 is a histone demethylase that modifies the methylation of homeobox and bone morphogenetic proteinsList of EC numbers (EC 3) (15,553 words) [view diff] exact match in snippet view article
hydrolase * EC 3.3.2.13: chorismatase * EC 3.3.2.14: 2,4-dinitroanisole O-demethylase * EC 3.3.2.15: trans-2,3-dihydro-3-hydroxyanthranilic acid synthase *Epigenome editing (3,122 words) [view diff] exact match in snippet view article find links to article
translocation methylcytosine dioxygenase 1 (TET1), Lysine (K)-specific demethylase 1A (LSD1) and Calcium and integrin binding protein 1 (CIB1). The usePenicillium digitatum (3,387 words) [view diff] exact match in snippet view article find links to article
imazalil is suggested to lie in the over-expression of the sterol 14α-demethylase (CYP51) protein caused by a 199 base-pair insertion into the promoterAkane Kawamura (463 words) [view diff] exact match in snippet view article find links to article
2011). "The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases". EMBO Reports. 12 (5): 463–9. doi:10.1038/EMBOR.2011.43. ISSN 1469-221XTEDC2 (1,503 words) [view diff] exact match in snippet view article find links to article
or threonine that could be phosphorylated. KDM1A, a lysine-specific demethylase, was shown to be physically associated with TEDC2. TEDC2 also interactsIlya B. Tsyrlov (1,337 words) [view diff] exact match in snippet view article find links to article
PMID 475855. Tsyrlov, I. B.; Gerasimov, K. E. (1991). "Aminopyrine-N-demethylase. I. Directed modification of substrates' structure as a way of productionCoiled-coil domain-containing 37 (FLJ40083) (820 words) [view diff] exact match in snippet view article
histone-lysine N-methyltransferase (SUV39H2), and lysine-specific histone demethylase 1A (KDM1A). In a study of the genes expressed in lung squamous cell carcinomasJohn McGeehan (1,310 words) [view diff] exact match in snippet view article find links to article
Michael F. (2018-06-27). "A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion". Nature Communications. 9 (1): 2487. Bibcode:2018NatCoNeuroepigenetics (3,869 words) [view diff] exact match in snippet view article find links to article
An eraser, neuroLSD1, is a modified version of the original Lysine Demethylase 1(LSD1) that exists only in neurons and assists with neuronal maturationEpitranscriptome (7,732 words) [view diff] exact match in snippet view article find links to article
demethylase found in mammals that removes the methyl group of m6A. The second one is the fat mass and obesity associated protein (FTO), a demethylaseCoiled-coil domain containing 74a (1,231 words) [view diff] exact match in snippet view article find links to article
post-translational methylation, CCDC74A has been shown to interact with the lysine demethylase KDM1A through a yeast 2-hybrid assay. Additionally, through a yeast 2-hybridLong non-coding RNA (12,398 words) [view diff] exact match in snippet view article find links to article
factors by coordinating intrachromosomal looping and recruitment of DNA demethylase TET2. In Drosophila, long ncRNAs induce the expression of the homeoticTMEM271 (922 words) [view diff] exact match in snippet view article find links to article
increased expression in a tissue with resistance to SP, a lysine-specific demethylase-1 inhibitor drug used to treat Ewing’s Sarcoma. GRCh38: Ensembl release2,2',3,3',4,4'-Hexachlorobiphenyl (1,866 words) [view diff] exact match in snippet view article find links to article
found increased activation of ethoxyresorufin deethylase and aminopyrine demethylase. However, while also observing an increased liver wight, it did not findC1orf68 (1,750 words) [view diff] exact match in snippet view article find links to article
Guoqing (2014). "Human Chromatin Related Protein Interactions Identify a Demethylase Complex Required for Chromosome Segregation". Cell Reports. 8 (1): 297–310Epigenetics of schizophrenia (5,482 words) [view diff] exact match in snippet view article find links to article
transcripts in patients experiencing psychotic symptoms. HMT (histone demethylase) inhibitors also act on histones. They prevent the demethylation of theTransgenerational trauma (12,495 words) [view diff] exact match in snippet view article find links to article
contextual fear conditioning altering FTO mRNA, which encodes an RNA demethylase. That suggests RNA modifications may have been altered in response toBioenhancer (2,375 words) [view diff] exact match in snippet view article find links to article
different enzymes: aryl hydrocarbon hydroxylase (AHH), ethylmorphine N-demethylase, Uridine diphosphate glucuronic_acid, Uridine diphosphate glucuronyltransferaseNBPF26 (718 words) [view diff] exact match in snippet view article find links to article
nuclease (multifunctional DNA repair enzyme) 1 (APEX1), lysine (K)-specific demethylase 1A (KDM1A), trans-golgi network protein 2 (TGOLN2), and tripartite motifStress granule (12,548 words) [view diff] exact match in snippet view article find links to article
Reineke LC, Jain A, Jung SY, Lloyd RE (November 2017). "Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of theTopical antifungal (3,320 words) [view diff] exact match in snippet view article find links to article
target the ergosterol biosynthetic pathway by inhibiting the C-14 α-demethylase, a cytochrome P450 enzyme, thus preventing the demethylation of lanosterolEpigenetic therapy (5,831 words) [view diff] exact match in snippet view article find links to article
and MMP-9 genes, an increase in transcription of LSD1, a H3K4 and H3K9 demethylase, and various DNA Methyl-Transferases (DNMTs), and increased presenceInduced cell cycle arrest (3,277 words) [view diff] exact match in snippet view article find links to article
Induces Cytokinesis Arrest in Cells Expressing a Mutated Sterol-14α-Demethylase in the Ergosterol Biosynthesis Pathway". Genetics. 204 (3): 959–973.RNA-directed DNA methylation (14,860 words) [view diff] exact match in snippet view article find links to article
methylation and demethylation activity. Interestingly, expression of the DNA demethylase ROS1 is directly tied to RdDM activity: DNA methylation over a TE targetedJacob Hanna (5,562 words) [view diff] exact match in snippet view article find links to article
regulators influencing iPSC derivation efficiency such as the role of H3K27 demethylase Utx in iPS formation, and first demonstrated the deterministic reprogrammingX-chromosome reactivation (5,094 words) [view diff] exact match in snippet view article find links to article
M, Ghariani SC, et al. (January 2012). "Deletion of KDM6A, a histone demethylase interacting with MLL2, in three patients with Kabuki syndrome". American