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searching for Developmental toxicity 92 found (113 total)

Piperonyl butoxide (2,928 words) [view diff] case mismatch in snippet view article find links to article

Alexander A.; McLaughlin, Matthew T.; Lipinski, Robert J. (2019). "Developmental Toxicity Assessment of Piperonyl Butoxide Exposure Targeting Sonic Hedgehog

Indole-3-acetic acid (2,765 words) [view diff] no match in snippet view article find links to article

Indole-3-acetic acid (IAA, 3-IAA) is the most common naturally occurring plant hormone of the auxin class. It is the best known of the auxins, and has

Joseph F. Holson (4,154 words) [view diff] exact match in snippet view article find links to article

Holson's career, while at NCTR, he led studies that assessed the developmental toxicity of FD&C Red No. 2, an amaranth dye, and the herbicide 2,4,5‐T (a

OECD Guidelines for the Testing of Chemicals (152 words) [view diff] case mismatch in snippet view article find links to article

Reproduction/Developmental Toxicity Screening Test 422 Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test

Nivalenol (3,550 words) [view diff] exact match in snippet view article find links to article

acute/subacute, subchronic, chronic and carcinogenicity, genotoxicity, developmental toxicity studies and studies on reproduction, immunotoxicity/hematotoxycity

Monobenzyl phthalate (350 words) [view diff] exact match in snippet view article find links to article

PMID 29328989. Ema M, Harazono A, Miyawaki E, Ogawa Y (July 1996). "Developmental toxicity of mono-n-benzyl phthalate, one of the major metabolites of the

Chlormequat (737 words) [view diff] exact match in snippet view article find links to article

670 mg/kg. Exposure to high levels of chlormequat has been linked to developmental toxicity in animal models. Chlormequat has not previously been registered

Lithium hypochlorite (250 words) [view diff] exact match in snippet view article find links to article

Hoberman A. M.; Deprospo J. R.; Lochry E. A.; Christian M. S. (1990). "Developmental toxicity study of orally administered lithium hypochlorite in rats". Journal

Heneicosane (348 words) [view diff] exact match in snippet view article find links to article

Lomash, V; Jatav, PC; Kumar, A; Pant, SC (January 2016). "Prenatal developmental toxicity study of n-heneicosane in Wistar rats". Toxicology and Industrial

Gambogic acid (1,127 words) [view diff] exact match in snippet view article find links to article

the mouse central nervous system. In mice gambogic acid causes developmental toxicity in a dose-dependent manner, including low birth weight and inhibitory

Herbal Essences (574 words) [view diff] exact match in snippet view article find links to article

2023. Herbal Essences Official website Daston GP (August 2004). "Developmental toxicity evaluation of butylparaben in Sprague-Dawley rats". Birth Defects

Homosalate (702 words) [view diff] exact match in snippet view article find links to article

Jarry H, Wuttke W, Lichtensteiger W (2004). "Endocrine activity and developmental toxicity of cosmetic UV filters--an update". Toxicology. 205 (1–2): 113–122

Prallethrin (1,070 words) [view diff] exact match in snippet view article find links to article

toxicity studies (subchronic and chronic oral studies in dogs, developmental toxicity studies in the rat and rabbit, 21-day dermal and 28-day inhalation

Antimony trioxide (1,080 words) [view diff] case mismatch in snippet view article find links to article

E.; Schroeder, R. E.; Zwick, L.; Serex, T. (2004). "Inhalation Developmental Toxicity Studies In Rats With Antimony(III) oxide (Sb2O3)". Toxicologist

Tasimelteon (1,110 words) [view diff] exact match in snippet view article find links to article

studies, administration of tasimelteon during pregnancy resulted in developmental toxicity (embryofetal mortality, neurobehavioral impairment, and decreased

Nickel(II) sulfate (1,095 words) [view diff] exact match in snippet view article

studies of highly exposed female workers have not shown adverse developmental toxicity effects. K. Lascelles, L. G. Morgan, D. Nicholls, D. Beyersmann

ISO 10993 (435 words) [view diff] case mismatch in snippet view article find links to article

Hemocompatibility Chronic Toxicity Carcinogenicity Reproductive/Developmental Toxicity Degradation Category Contact Surface device Intact skin A X X X

Difluoromethane (1,158 words) [view diff] exact match in snippet view article find links to article

the bronzing of leaves. Difluoromethane shows slight maternal and developmental toxicity at concentrations of approximately 50,000 ppm in rats, but not in

Food additive (2,743 words) [view diff] exact match in snippet view article find links to article

data) and chronic toxicity and carcinogenity; reproductive and developmental toxicity. Recent work has demonstrated that certain food additives such as

In vitro (3,123 words) [view diff] exact match in snippet view article find links to article

based kinetic modeling to predict dose–response curves for in vivo developmental toxicity of glycol ethers in rat and man". Toxicological Sciences. 118 (2):

Sunset yellow FCF (1,117 words) [view diff] exact match in snippet view article find links to article

: 465 Sunset yellow FCF has no carcinogenicity, genotoxicity, or developmental toxicity in the amounts at which it is used.: 465 It has been claimed since

Cyanazine (1,718 words) [view diff] case mismatch in snippet view article find links to article

“Characterization of Maternal Influence on Teratogenicity: An Assessment of Developmental Toxicity Studies for the Herbicide Cyanazine1,2,” Regul. Toxicol. Pharmacol

Ponceau 4R (751 words) [view diff] exact match in snippet view article find links to article

carcinogenicity, genotoxicity, neurotoxicity, or reproductive and developmental toxicity at the permitted dietary exposures; the European acceptable daily

Vibegron (2,109 words) [view diff] exact match in snippet view article find links to article

vibegron during the period of organogenesis and showed no embryo-fetal developmental toxicity up to 300 mg/kg/day. Similar data was found in rabbits. Maternal

ZebraBox (360 words) [view diff] exact match in snippet view article find links to article

Wang W, Ma Q, Ding X, Xu Y, He M, Xu J, et al. (March 2022). "Developmental toxicity of bromoacetamide via the thyroid hormone receptors-mediated disruption

CYP2J2 (1,896 words) [view diff] exact match in snippet view article find links to article

biotransformation enzymes in human fetal olfactory mucosa: potential roles in developmental toxicity". Toxicology and Applied Pharmacology. 165 (2): 158–62. doi:10.1006/taap

Bevirimat (1,677 words) [view diff] exact match in snippet view article find links to article

potential for cytotoxicity. There is no evidence of any reproductive or developmental toxicity and it is not immunotoxic. Bevirimat was initially evaluated for

Methemoglobinemia (2,555 words) [view diff] exact match in snippet view article find links to article

an update on methemoglobinemia occurrence and reproductive and developmental toxicity". Regulatory Toxicology and Pharmacology. 23 (1 Pt 1): 35–43. doi:10

Hydroxycarbamide (1,767 words) [view diff] exact match in snippet view article find links to article

(August 2007). "NTP-CERHR expert panel report on the reproductive and developmental toxicity of hydroxyurea". Birth Defects Research. Part B, Developmental and

Perfluorooctanesulfonic acid (5,627 words) [view diff] exact match in snippet view article find links to article

PMID 11999053. Lau C, Butenhoff JL, Rogers JM (July 2004). "The developmental toxicity of perfluoroalkyl acids and their derivatives". Toxicol. Appl. Pharmacol

Chilean rose tarantula (1,407 words) [view diff] exact match in snippet view article find links to article

(2013). "Old World vs. New World: a preliminary comparison of the developmental toxicity of venom from two tarantula species, Grammostola rosea and Haplopelma

Plasticizer (2,637 words) [view diff] exact match in snippet view article find links to article

have been classified as potential endocrine disruptors with some developmental toxicity reported. Plasticizers can escape plastics due to migration and

Platinum nanoparticle (5,344 words) [view diff] exact match in snippet view article find links to article

through protein levels. Last is the developmental toxicity that can occur as an organism grows. Developmental toxicity looks at the impact the nanoparticle

Mir-430 microRNA precursor family (784 words) [view diff] exact match in snippet view article find links to article

Schönbach C (ed.). "Analysis of microRNA expression in embryonic developmental toxicity induced by MC-RR". PLOS ONE. 6 (7): e22676. Bibcode:2011PLoSO..

Bis(2-ethylhexyl) terephthalate (548 words) [view diff] exact match in snippet view article

[sic] to DEHP, has been shown to have potential reproductive and developmental toxicity." The NOAELs quoted are actually quite high, indicating the potential

N-Nitroso-N-methylurea (377 words) [view diff] case mismatch in snippet view article find links to article

and Mutagenesis 11:1-10. Faustman, E., et al. (1989). In Vitro Developmental Toxicity of Five Direct-Acting Alkylating Agents in Rodent Embryos: Structure-Activity

Cosmetology (4,219 words) [view diff] exact match in snippet view article find links to article

Donald, J. M; Hooper, K; Hopenhayn-Rich, C (1991). "Reproductive and developmental toxicity of toluene: A review". Environmental Health Perspectives. 94: 237–44

Polyethylene glycol (3,904 words) [view diff] case mismatch in snippet view article find links to article

May 2017. Andersen FA (1999). "Special Report: Reproductive and Developmental Toxicity of Ethylene Glycol and Its Ethers". International Journal of Toxicology

Polyethylene glycol (3,904 words) [view diff] case mismatch in snippet view article find links to article

May 2017. Andersen FA (1999). "Special Report: Reproductive and Developmental Toxicity of Ethylene Glycol and Its Ethers". International Journal of Toxicology

Safflower (2,950 words) [view diff] exact match in snippet view article find links to article

grade safflower concentrate: No evidence for reproduction and early developmental toxicity". Reproductive Toxicology. 104: 155–165. doi:10.1016/j.reprotox

Uranium in the environment (3,454 words) [view diff] exact match in snippet view article find links to article

PMID 12539863. S2CID 25310165. J. L. Domingo (2001). "Reproductive and developmental toxicity of natural and depleted uranium: a review". Reprod. Toxicol. 15

Manganism (2,327 words) [view diff] exact match in snippet view article find links to article

Treinen, Kimberley A.; Gray, Tim J. B.; Blazak, William F. (1995). "Developmental toxicity of mangafodipir trisodium and manganese chloride in Sprague-Dawley

Chromium(III) phosphate (1,667 words) [view diff] exact match in snippet view article

affected. This may ultimately lead to nephrotoxicity, reproductive and developmental toxicity due to tissue damage, necrosis and inflammation. Mustafa, S.; Murtaza

Nimetazepam (1,803 words) [view diff] exact match in snippet view article find links to article

Takeno S, Hirano Y, Kitamura A, Sakai T (August 1993). "Comparative developmental toxicity and metabolism of nitrazepam in rats and mice". Toxicology and Applied

Polychlorinated dibenzodioxins (6,837 words) [view diff] exact match in snippet view article find links to article

Kransler KM, McGarrigle BP, Olson JR (January 2007). "Comparative developmental toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the hamster, rat and guinea

Iodoacetic acid (1,061 words) [view diff] case mismatch in snippet view article find links to article

(1996). "Quantitative Structure-Activity Relationships for the Developmental Toxicity of Haloacetic Acids in Mammalian Whole Embryo Culture". Teratology

Bread (6,359 words) [view diff] exact match in snippet view article find links to article

Acrylamide is neurotoxic, has adverse effects on male reproduction and developmental toxicity and is carcinogenic. A study has found that more than 99 percent

Salicylic acid (3,439 words) [view diff] exact match in snippet view article find links to article

cosmetic products demonstrates no evidence of a health risk from developmental toxicity". Regulatory Toxicology and Pharmacology. 94: 245–251. doi:10.1016/j

Iodopropynyl butylcarbamate (1,236 words) [view diff] exact match in snippet view article find links to article

be a non-carcinogen with no genotoxicity and in reproductive and developmental toxicity studies using rats and mice, IPBC had no significant effect on fertility

T-2 mycotoxin (3,180 words) [view diff] exact match in snippet view article find links to article

Zhang T, Zhao J, Huang L, Peng S (April 2014). "T-2 toxin induces developmental toxicity and apoptosis in zebrafish embryos". Journal of Environmental Sciences

Magnetofection (2,407 words) [view diff] exact match in snippet view article find links to article

"Effects of iron oxide nanoparticles: Cytotoxicity, genotoxicity, developmental toxicity, and neurotoxicity". Environmental and Molecular Mutagenesis. 56

Boric acid (4,832 words) [view diff] exact match in snippet view article find links to article

Substances Lodz, Poland, boric acid in high doses shows significant developmental toxicity and teratogenicity in rabbit, rat, and mouse fetuses, as well as

Bisphenol S (3,410 words) [view diff] case mismatch in snippet view article find links to article

Gaballah, Shaza; Lamendella, Regina; Tal, Tamara (2019-02-01). "Host Developmental Toxicity of BPA and BPA Alternatives Is Inversely Related to Microbiota Disruption

Thallium (5,778 words) [view diff] exact match in snippet view article find links to article

exposure to thallium increases the risk of reproductive toxicity or developmental toxicity. Chronic high level exposure to thallium through inhalation has

Benzyl butyl phthalate (3,110 words) [view diff] exact match in snippet view article find links to article

Reproduction : phthalates expert panel report on the reproductive and developmental toxicity of butyl benzyl phthalate ଝ (Vol. 16) NTP - CERHR. (2003). NTP-CERHR

Rabbit (8,406 words) [view diff] exact match in snippet view article find links to article

Carney, Edward W (2000). "The rabbit as a model for reproductive and developmental toxicity studies". Reproductive Toxicology. 14 (6): 477–493. doi:10

In vitro to in vivo extrapolation (746 words) [view diff] exact match in snippet view article find links to article

based kinetic modeling to predict dose–response curves for in vivo developmental toxicity of glycol ethers in rat and man". Toxicological Sciences. 118 (2):

1,1,1,3,3,3-Hexachloropropane (978 words) [view diff] exact match in snippet view article find links to article

S. M. Munley, M. S. Swanson, K. M. McGown, M. E. Hurtt (2003): "Developmental toxicity and genotoxicity studies of 1,1,1,3,3,3-hexachloropropane (HCC-230fa)

Perfluorooctanoic acid (12,492 words) [view diff] exact match in snippet view article find links to article

hormone levels at very high concentrations Animal studies show developmental toxicity from reduced birth size, physical developmental delays, endocrine

Diisobutyl phthalate (3,721 words) [view diff] exact match in snippet view article find links to article

2012). "Genomic biomarkers of phthalate-induced male reproductive developmental toxicity: a targeted RT-PCR array approach for defining relative potency"

Indo-Pacific humpback dolphin (3,919 words) [view diff] exact match in snippet view article find links to article

marine mammals such as disease susceptibility, reproductive and developmental toxicity. Constant absorption of organic pollutants like plastic can be transferred

Imidacloprid (4,909 words) [view diff] exact match in snippet view article find links to article

by the U.S. EPA (group E). It is not listed for reproductive or developmental toxicity, but is listed on EPA's Tier 1 Screening Order for chemicals to

Nickel (9,845 words) [view diff] exact match in snippet view article find links to article

studies of highly exposed female workers have not shown adverse developmental toxicity effects. People can be exposed to nickel in the workplace by inhalation

Pharmacy automation (2,725 words) [view diff] exact match in snippet view article find links to article

characteristics in humans or animals: carcinogenicity, teratogenicity or developmental toxicity, reproductive toxicity, organ toxicity at low doses, genotoxicity

Hedgehog signaling pathway (6,895 words) [view diff] case mismatch in snippet view article find links to article

Fink DM, Heyne GW, Melberg CG, Nelson KF, et al. (October 2019). "Developmental Toxicity Assessment of Piperonyl Butoxide Exposure Targeting Sonic Hedgehog

Phthalates (8,205 words) [view diff] exact match in snippet view article find links to article

GS, Murk AJ, Ropstad E, et al. (April 2009). "Reproductive and developmental toxicity of phthalates". Journal of Toxicology and Environmental Health Part

Microcystin-LR (3,069 words) [view diff] exact match in snippet view article find links to article

passes the intestinal barrier. Microcystins do not appear to show developmental toxicity. The WHO states microcystin-LR has no mutagenic effect. However

Novaluron (1,561 words) [view diff] exact match in snippet view article find links to article

effects were noted up to a dose of 1000 mg/kg/day and no maternal or developmental toxicity was noted. Based on available studies, there is also no concern

JeAnne Burg (487 words) [view diff] exact match in snippet view article find links to article

Kirby N. (1987), "Evaluation of 60 chemicals in a preliminary developmental toxicity test", Teratogenesis, Carcinogenesis, and Mutagenesis, 7 (1), Wiley:

Endosulfan (6,849 words) [view diff] exact match in snippet view article find links to article

hormones and animal studies have demonstrated its reproductive and developmental toxicity, especially among males. A number of studies have documented that

Aflatoxin B1 (3,574 words) [view diff] exact match in snippet view article find links to article

PMID 19642212. Geissler, Francis; Faustman, Elaine M (1988). "Developmental toxicity of aflatoxin B1 in the rodent embryo in vitro: Contribution of exogenous

Methanol economy (5,693 words) [view diff] case mismatch in snippet view article find links to article

(2004). "NTP-CERHR Expert Panel Report on the Reproductive and Developmental Toxicity of Methanol". Reproductive Toxicology. 18 (3): 303–390. doi:10.1016/j

Scathophaga stercoraria (2,750 words) [view diff] case mismatch in snippet view article find links to article

00984.x. PMID 22007907. Oecd (2008). Test No. 228: Determination of Developmental Toxicity of a Test Chemical to Dipteran Dung Flies (Scathophaga stercoraria

Methoxyacetic acid (677 words) [view diff] exact match in snippet view article find links to article

one-carbon moieties in 2-methoxyethanol and 2-methoxyacetic acid-induced developmental toxicity". Toxicology and Applied Pharmacology. 99 (1): 98–109. doi:10

Zebrafish (11,535 words) [view diff] case mismatch in snippet view article find links to article

"Automated Morphological Feature Assessment for Zebrafish Embryo Developmental Toxicity Screens". Toxicological Sciences. 167 (2): 438–449. doi:10.1093/toxsci/kfy250

Depleted uranium (14,652 words) [view diff] exact match in snippet view article find links to article

PMID 12539863. S2CID 25310165. Domingo JL (2001). "Reproductive and developmental toxicity of natural and depleted uranium: a review". Reproductive Toxicology

Glyphosate (16,153 words) [view diff] exact match in snippet view article find links to article

Kimmel GL, Kimmel CA, Williams AL, DeSesso JM (2013). "Evaluation of developmental toxicity studies of glyphosate with attention to cardiovascular development"

Electronic waste (15,937 words) [view diff] exact match in snippet view article find links to article

in mice have found the following health effects: Hepatotoxicity, developmental toxicity, immunotoxicity, hormonal effects and carcinogenic effects. Studies

Toxic Substances Control Act of 1976 (11,660 words) [view diff] exact match in snippet view article find links to article

Koduru, Sudha (June 1, 2000). "Chemicals in the environment and developmental toxicity to children: a public health and policy perspective". Environmental

Toxicodynamics (3,269 words) [view diff] case mismatch in snippet view article find links to article

Toxicological Characteristics of Endocrine-Disrupting Chemicals: Developmental Toxicity, Carcinogenicity, and Mutagenicity. Journal of Toxicology and Environmental

Pharmacoepigenetics (4,224 words) [view diff] exact match in snippet view article find links to article

mass spectrometry-based histone screening for assessing epigenetic developmental toxicity". Scientific Reports. 12 (1): 1256. doi:10.1038/s41598-022-05268-x

Topical fluoride (2,642 words) [view diff] exact match in snippet view article find links to article

development. While the exact pathophysiology of fluoride-induced developmental toxicity is not completely understood, most research suggested that excessive

Nutritional neuroscience (15,345 words) [view diff] exact match in snippet view article find links to article

Treinen, Kimberley A.; Gray, Tim J. B.; Blazak, William F. (1995). "Developmental toxicity of mangafodipir trisodium and manganese chloride in Sprague-Dawley

Diafenthiuron (1,592 words) [view diff] exact match in snippet view article find links to article

Gao, Bo; Xiao, Peng; Li, Wenhua (May 2023). "Diafenthiuron causes developmental toxicity in zebrafish (Danio rerio)". Chemosphere. 323: 138253. Bibcode:2023Chmsp

Composition of electronic cigarette aerosol (12,826 words) [view diff] exact match in snippet view article find links to article

chloride 0.09 cerebellar lesions U.S. EPA Methyl ethyl ketone 5 developmental toxicity U.S. EPA Naphthalene 0.003 nasal effects U.S. EPA N-nitrosodi-n-butylamine

Perfluorodecanoic acid (3,380 words) [view diff] exact match in snippet view article find links to article

1235–1244. doi:10.1002/jlcr.2580241011. Harris, M (April 1989). "Developmental toxicity of perfluorodecanoic acid in C57BL/6N mice". Fundamental and Applied

Cancer epigenetics (12,530 words) [view diff] exact match in snippet view article find links to article

mass spectrometry-based histone screening for assessing epigenetic developmental toxicity". Scientific Reports. 12 (1): 1256. Bibcode:2022NatSR..12.1256V

Single-walled carbon nanohorn (7,074 words) [view diff] exact match in snippet view article find links to article

assessments, including chronic (repeated dose), reproductive, and developmental toxicity studies, are still needed, yet the present results strongly suggest

Ethyl lauroyl arginate (3,562 words) [view diff] exact match in snippet view article find links to article

humans, mutagenic, acute, subchronic, chronic, reproductive, and developmental toxicity. The results of these studies have been published in the prestigious

Darryl B. Hood (2,225 words) [view diff] exact match in snippet view article find links to article

Hood DB, Ramesh A, Chirwa S, Khoshbouei H, Archibong AE (2011). "Developmental toxicity of polycyclic aromatic hydrocarbons". Reproductive and Developmental

Electronic cigarette and e-cigarette liquid marketing (38,571 words) [view diff] exact match in snippet view article find links to article

Theodore A.; Spindel, Eliot; Stroud, Laura; Wakschlag, Lauren (2017). "Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for

Bis(2-ethylhexyl)tetrabromophthalate (2,807 words) [view diff] exact match in snippet view article

the European Union, which resulted in a request for a prenatal developmental toxicity study. A compliance check (the testing of products manufactured