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Longer titles found: Cross electrophile coupling (view)

searching for Electrophile 129 found (294 total)

Lectka enantioselective beta-lactam synthesis (317 words) [view diff] exact match in snippet view article find links to article

the nucleophile rather than the electrophile. Similarly, the imine in the Lectka synthesis behaves as the electrophile rather than the nucleophile as seen

Phosphorus trichloride (1,731 words) [view diff] no match in snippet view article find links to article

Phosphorus trichloride is an inorganic compound with the chemical formula PCl3. A colorless liquid when pure, it is an important industrial chemical, being

Aminoacetonitrile (377 words) [view diff] exact match in snippet view article find links to article

owing to the incompatibility of the amine nucleophile and the nitrile electrophile. For this reason it is usually encountered as the chloride and bisulfate

Polymerization (1,443 words) [view diff] exact match in snippet view article find links to article

oligomers. Generally, because formaldehyde is an exceptionally reactive electrophile it allows nucleophilic addition of hemiacetal intermediates, which are

Pinner reaction (452 words) [view diff] exact match in snippet view article find links to article

poor the nitrile is. For example: an electron-poor nitrile is a good electrophile (readily susceptible to attack from alkoxides etc.) but a poor nucleophile

Organocatalysis (1,720 words) [view diff] exact match in snippet view article find links to article

iminium catalysis (by forming catalytic quantities of an activated iminium electrophile). This mechanism is typical for covalent organocatalysis. Covalent binding

Yimon Aye (471 words) [view diff] exact match in snippet view article find links to article

technologies, new methods to facilitate the study of unconventional electrophile-regulated stress signaling paradigms. REX technologies were one of the

Arenium ion (494 words) [view diff] exact match in snippet view article find links to article

system, as depicted on the following resonance structures: A complexed electrophile can contribute to the stability of arenium ions. Salts of benzenium ion

Tetrachlorocyclopropene (138 words) [view diff] exact match in snippet view article find links to article

are thought to proceed via the intermediacy of trichlorocyclopropenium electrophile (C3Cl3+). Oliver Reiser; Armin de Meijere (2001). "Tetrachlorocyclopropene"

Heterogeneous metal catalyzed cross-coupling (2,307 words) [view diff] exact match in snippet view article find links to article

Pd-catalyzed Suzuki reaction still proceeds via oxidative addition of the electrophile by Pd(0), transmetallation of a boronate, and reductive elimination to

Ionic hydrogenation (718 words) [view diff] exact match in snippet view article find links to article

the addition of a hydride to substrate that has been activated by an electrophile. Some ionic hydrogenations entail addition of H2 to the substrate and

Sulfonium-based oxidation of alcohols to aldehydes (729 words) [view diff] exact match in snippet view article find links to article

and DMSO requires a dehydrating agent for removal of H2O, ideally an electrophile simultaneously activating DMSO. In contrast, methods generating the sulfonium

Bleomycin hydrolase (1,028 words) [view diff] exact match in snippet view article find links to article

through evolution. Its biological function is hydrolysis of the reactive electrophile homocysteine thiolactone. Another of its activities is metabolic inactivation

Acetoacetic ester synthesis (225 words) [view diff] exact match in snippet view article find links to article

LiCH2C(O)CH(Na)CO2Et + BuH The dianion (i.e., LiCH2C(O)CH(Na)CO2Et) adds electrophile to the terminal carbon as depicted in the following simplified form:

Tetrachloroaluminate (189 words) [view diff] exact match in snippet view article find links to article

alkyl halide reacts with the strong Lewis acid to form an activated electrophile composed of the tetrachloroaluminate ion and the alkyl group. The aromatic

Living cationic polymerization (1,072 words) [view diff] exact match in snippet view article find links to article

binary system, for example an alcohol and a Lewis acid. The active electrophile is then a proton and the counter ion the remaining alkoxide which is

Reductive dehalogenation of halo ketones (1,241 words) [view diff] exact match in snippet view article find links to article

agents to afford the parent ketones, derivatives functionalized with electrophiles, or products of dimerization. The mechanism of reduction itself depends

Malondialdehyde (922 words) [view diff] exact match in snippet view article find links to article

This compound is a reactive aldehyde and is one of the many reactive electrophile species that cause toxic stress in cells and form covalent protein adducts

Phenyl group (1,042 words) [view diff] exact match in snippet view article find links to article

include phenyllithium (C6H5Li) and phenylmagnesium bromide (C6H5MgBr). Electrophiles are attacked by benzene to give phenyl derivatives: C 6 H 6 + E + ⟶

Decarboxylation (1,200 words) [view diff] exact match in snippet view article find links to article

decarboxylation of a picolinic acid gives a stable carbene that attacks a carbonyl electrophile. Oxidative decarboxylations are generally radical reactions. These include

Acetyl fluoride (150 words) [view diff] exact match in snippet view article find links to article

Masahiro; Ando, Hisanori (1995). "Dual Reactivity of the Formyl Cation as an Electrophile and a Bransted Acid in Superacids". Journal of Organic Chemistry. 60

Transition metal formyl complex (374 words) [view diff] exact match in snippet view article find links to article

hydride reagents: [Re(CO)6]+ + H− → (CO)5ReCHO The CO ligand is the electrophile and the hydride (provided typically from a borohydride) is the nucleophile

Ortho effect (938 words) [view diff] exact match in snippet view article find links to article

steric effects which determines the regioselectivity of an incoming electrophile in disubstituted benzene compounds When a substituent group is located

Urocanase (381 words) [view diff] exact match in snippet view article find links to article

NAD+ (Nicotinamide Adnene Dinucleotide) groups. The NAD+ groups act as electrophiles, attaching to the top carbon of the urocanate which leads to sigmatropic

MAFG (2,631 words) [view diff] exact match in snippet view article find links to article

from MARE. The latter DNA sequences have been recognized as antioxidant/electrophile response elements or NF-E2-binding motifs to which Nrf2-sMaf heterodimers

MAFK (2,536 words) [view diff] exact match in snippet view article find links to article

from MARE. The latter DNA sequences have been recognized as antioxidant/electrophile response elements or NF-E2-binding motifs to which Nrf2-sMaf heterodimers

Hypobromous acid (345 words) [view diff] exact match in snippet view article find links to article

, & de Souza, A. R. (2015). Hypobromous acid, a powerful endogenous electrophile: Experimental and theoretical studies. Journal of inorganic biochemistry

JT-010 (244 words) [view diff] exact match in snippet view article find links to article

AL, He Q, Borgnia MJ, et al. (March 2020). "Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel". Neuron. 105 (5): 882–894

Aldol reactions (957 words) [view diff] exact match in snippet view article find links to article

an enolate or enolation as a nucleophile to a carbonyl moiety as an electrophile. This produces a β-hydroxyaldehyde or β-hydroxyketone. In an aldol condensation

Gattermann reaction (587 words) [view diff] exact match in snippet view article find links to article

to form a carbonyl complex, which is then transformed into the active electrophile. Houben–Hoesch reaction Stephen aldehyde synthesis Smith, Michael B.;

Halohydrin (835 words) [view diff] exact match in snippet view article find links to article

reaction is a form of electrophilic addition, with the halogen acting as electrophile. In that regard, it resembles the halogen addition reaction and proceeds

Racemic mixture (1,824 words) [view diff] exact match in snippet view article find links to article

(such as an sp2 carbon atom or a carbocation intermediate) acting as an electrophile. The nucleophile will have a 50% probability of 'hitting' either of the

Histidine ammonia-lyase (638 words) [view diff] exact match in snippet view article find links to article

ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile". Biochemistry. 38 (17): 5355–5361. doi:10.1021/bi982929q. PMID 10220322

Pyruvate decarboxylase (1,153 words) [view diff] exact match in snippet view article find links to article

decarboxylation of pyruvate, the TPP stabilizes the carbanion intermediates as an electrophile by noncovalent bonds. Specifically, the pyridyl nitrogen N1' and the

Diethyl oxomalonate (1,343 words) [view diff] exact match in snippet view article find links to article

Diethyl oxomalonate reacts because of its highly polarized keto group as electrophile in addition reactions and is a highly active reactant in pericyclic reactions

B type proanthocyanidin (449 words) [view diff] exact match in snippet view article find links to article

equimolar amount of dimeric catechin nucleophile and monomeric catechin electrophile catalyzed by AgOTf or AgBF4. The coupled product can be transformed into

Nitrosonium (585 words) [view diff] exact match in snippet view article find links to article

These species are quite different, however. Nitronium is a more potent electrophile than is nitrosonium, as anticipated by the fact that the former is derived

Williamson ether synthesis (1,339 words) [view diff] exact match in snippet view article find links to article

mechanism. In an SN2 reaction mechanism there is a backside attack of an electrophile by a nucleophile and it occurs in a concerted mechanism (happens all

Silicon tetrachloride (1,137 words) [view diff] exact match in snippet view article find links to article

mixture using fractional distillation. Silicon tetrachloride is a classic electrophile in its reactivity. It forms a variety of organosilicon compounds upon

Chlorambucil (1,174 words) [view diff] exact match in snippet view article find links to article

over-expressed in cancer tissues. This is important since Chlorambucil, as an electrophile, is made less reactive by conjugation with glutathione, thereby making

Nickel(II) bromide (510 words) [view diff] exact match in snippet view article

(2016-06-01). "Intra- and Intermolecular Nickel-Catalyzed Reductive Cross-Electrophile Coupling Reactions of Benzylic Esters with Aryl Halides". Angewandte

Benzylic activation and stereocontrol in tricarbonyl(arene)chromium complexes (1,352 words) [view diff] exact match in snippet view article

involves enantioselective ortho-lithiation and in situ quenching with an electrophile. Isolation of the lithium arene and subsequent treatment with TMSCl led

Heteroatom-promoted lateral lithiation (1,692 words) [view diff] exact match in snippet view article find links to article

lithiation. The products of lateral lithiation react with a variety of electrophiles, including reactive alkyl halides (allylic, benzylic, and primary),

Organomercury chemistry (1,128 words) [view diff] exact match in snippet view article find links to article

nucleophiles, form strong coordination complexes with mercury(II), a soft electrophile. This mode of action makes them useful for affinity chromatography to

Polypyrrole (1,178 words) [view diff] exact match in snippet view article find links to article

thought to occur via the formation of the pi-radical cation C4H4NH+. This electrophile attacks the C-2 carbon of an unoxidized molecule of pyrrole to give a

Payne rearrangement (1,773 words) [view diff] exact match in snippet view article find links to article

epoxide isomer is difficult, as reaction of the epoxy alcohol with the electrophile is typically faster than migration. However, intramolecular electrophies

Hinsberg reaction (370 words) [view diff] exact match in snippet view article find links to article

account. Amines serve as nucleophiles in attacking the sulfonyl chloride electrophile, displacing chloride. The sulfonamides resulting from primary and secondary

Ethyl acetoacetate (506 words) [view diff] exact match in snippet view article find links to article

of ethylacetoacetate is also a useful building block, except that the electrophile adds to the terminal carbon. The strategy can be depicted in the following

Nitro compound (1,764 words) [view diff] exact match in snippet view article find links to article

sulfuric acid, which produce the nitronium ion (NO+2), which is the electrophile: + H+ The nitration product produced on the largest scale, by far

Tyrosine ammonia-lyase (212 words) [view diff] exact match in snippet view article find links to article

ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile". Biochemistry. 38 (17): 5355–61. doi:10.1021/bi982929q. PMID 10220322

Hydrogen-bond catalysis (4,562 words) [view diff] exact match in snippet view article find links to article

activate electrophiles by protonation. A powerful approach is the simultaneous activation of both partners in a reaction, e.g. nucleophile and electrophile, termed

Methanesulfonyl chloride (772 words) [view diff] exact match in snippet view article find links to article

precursor to many compounds because it is highly reactive. It is an electrophile, functioning as a source of the "CH3SO2+" synthon. Methanesulfonyl chloride

Picryl chloride (159 words) [view diff] exact match in snippet view article find links to article

electron-withdrawing nitro groups. Consequently picryl chloride is an electrophile as illustrated by its reactivity toward sulfite to give the sulfonate:

Cyanogen bromide (1,502 words) [view diff] exact match in snippet view article find links to article

and the beta carbon of the cysteine not electrophilic. The strongest electrophile would then be the cyanide carbon, which, if attacked by water, would

Diphenyl diselenide (556 words) [view diff] exact match in snippet view article find links to article

reaction is chlorination: Ph2Se2 + Cl2 → 2 PhSeCl PhSeCl is a powerful electrophile, used to introduce PhSe groups by reaction with a variety of nucleophiles

Organobromine chemistry (1,557 words) [view diff] exact match in snippet view article find links to article

reflects the easy oxidation of bromide to the equivalent of Br+, a potent electrophile. The enzyme vanadium bromoperoxidase, one of a larger family of bromoperoxidases

Aldehyde (3,000 words) [view diff] exact match in snippet view article find links to article

occurs when a nucleophilic alkene or alkyne reacts with an aldehyde as electrophile. The product of the Prins reaction varies with reaction conditions and

Arsabenzene (524 words) [view diff] exact match in snippet view article find links to article

of these heterobenzenes to undergo the Diels Alder reaction with this electrophile increases down the periodic table. Bismabenzene is so reactive that it

Para-Dimethylaminobenzaldehyde (527 words) [view diff] exact match in snippet view article find links to article

is the main ingredient in Ehrlich's reagent. It acts as a strong electrophile which reacts with the electron-rich α-carbon (2-position) of indole rings

Phenylalanine/tyrosine ammonia-lyase (285 words) [view diff] exact match in snippet view article find links to article

ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile". Biochemistry. 38 (17): 5355–61. doi:10.1021/bi982929q. PMID 10220322

Propylene (1,930 words) [view diff] exact match in snippet view article find links to article

Propylene is prochiral, meaning that binding of a reagent (such as a metal electrophile) to the C=C group yields one of two enantiomers. The majority of propene

UBE2V2 (1,677 words) [view diff] exact match in snippet view article find links to article

enzyme E2 variant 2". Farmer EE, Davoine C (August 2007). "Reactive electrophile species". Current Opinion in Plant Biology. 10 (4): 380–6. doi:10.1016/j

Fulvio Cacace (1,349 words) [view diff] exact match in snippet view article find links to article

tert-butyl ions with arenes. Remarkable selectivity of a gaseous, charged electrophile". (1976) "Gas-phase alkylation of xylenes by tert-butyl(1+) ions". (1977)

Solvent effects (1,914 words) [view diff] exact match in snippet view article find links to article

charge on the nucleophile, making it less available to react with the electrophile. The reactions involving charged transition metal complexes (cationic

Pyridoxal phosphate (2,933 words) [view diff] exact match in snippet view article find links to article

inhibitors of PLP enzymes are known. One type of inhibitor forms an electrophile with PLP, causing it to irreversibly react with the active site lysine

MAFF (gene) (1,840 words) [view diff] exact match in snippet view article

2002). "Differential induction of mafF, mafG and mafK expression by electrophile-response-element activators". The Biochemical Journal. 361 (Pt 2): 371–7

Ketimine Mannich reaction (3,407 words) [view diff] exact match in snippet view article find links to article

Michael addition had to be happening with the former aldehyde as an electrophile. Substituent studies have focused on increasing or decreasing steric

Base (chemistry) (3,041 words) [view diff] exact match in snippet view article

Archived from the original on 9 January 2022. Retrieved 9 January 2022. "Electrophile – Nucleophile – Basicity – Acidity – pH Scale". City Collegiate. Archived

Enolate (2,487 words) [view diff] exact match in snippet view article find links to article

exist in low concentrations, but they still undergo reactions with electrophiles. Many factors affect the behavior of enolates, especially the solvent

Methionine (2,980 words) [view diff] exact match in snippet view article find links to article

positive charge). The sulfur acts as a soft Lewis acid (i.e., donor/electrophile) which allows the S-methyl group to be transferred to an oxygen, nitrogen

Enamine (1,800 words) [view diff] exact match in snippet view article find links to article

nucleophilic than enolates). Thus they are better able to react with weaker electrophiles (for example, they can be used to open epoxides.) Most prominently,

Azide-alkyne Huisgen cycloaddition (2,635 words) [view diff] exact match in snippet view article find links to article

absence of a base. In the uncatalysed reaction the alkyne remains a poor electrophile. Thus high energy barriers lead to slow reaction rates. The ligands employed

Carbenium ion (1,489 words) [view diff] exact match in snippet view article find links to article

resulting from the strong bond between the benzene and the complexed electrophile. The smallest arenium ion is protonated benzene, C 6H+ 7. The benzenium

Aromatic compound (2,113 words) [view diff] exact match in snippet view article find links to article

are electrophilic aromatic substitution, when the active reagent is an electrophile, and nucleophilic aromatic substitution, when the reagent is a nucleophile

Transition metal dinitrogen complex (2,127 words) [view diff] exact match in snippet view article find links to article

dinitrogen complexes are susceptible to attack by electrophiles on nitrogen. When the electrophile is a proton, the reaction is of interest in the context

Erlotinib (1,993 words) [view diff] exact match in snippet view article find links to article

the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophile". Drug Metabolism and Disposition. 38 (7): 1238–1245. doi:10.1124/dmd

Hauser base (871 words) [view diff] exact match in snippet view article find links to article

complicates the functionalization of the metaled intermediate with an electrophile. Improved solubility and reactivity can be achieved by adding stoichiometric

Adenosine deaminase (3,014 words) [view diff] exact match in snippet view article find links to article

via tetrahedral intermediate. By either mechanism, Zn2+ as a strong electrophile activates a water molecule, which is deprotonated by the basic Asp295

SUMO enzymes (707 words) [view diff] exact match in snippet view article find links to article

and D.C. Liebler, Global shifts in protein sumoylation in response to electrophile and oxidative stress, Chem. Res. Toxicol. 17 (2004), pp. 1706–1715 T

Ugi's amine (1,790 words) [view diff] exact match in snippet view article find links to article

all other atoms. The high diastereoselectivity is independent of the electrophile used to trap the metalate, providing evidence for the stereoinductive

Ester (4,351 words) [view diff] exact match in snippet view article find links to article

ester synthesis, wherein the diester of malonic acid reacts with an electrophile (e.g., alkyl halide), and is subsequently decarboxylated. Another variation

Octanol-water partition coefficient (1,459 words) [view diff] exact match in snippet view article find links to article

5620200703. PMID 11434281. S2CID 25971836. Lipnick RL (1989). "Narcosis, electrophile and proelectrophile toxicity mechanisms: Application of SAR and QSAR"

Bromine compounds (2,374 words) [view diff] exact match in snippet view article find links to article

of the easy oxidation of bromide to the equivalent of Br+, a potent electrophile. The enzyme bromoperoxidase catalyzes this reaction. The oceans are estimated

Arsonic acid (functional group) (957 words) [view diff] exact match in snippet view article

is an electrophilic aromatic substitution, using arsenic acid as the electrophile. The reaction proceeds according to this idealized stoichiometry: C6H5NH2

Mentha pulegium (3,064 words) [view diff] exact match in snippet view article find links to article

inhibitors. The carbonyl center of the pulegone structure acts as a strong electrophile, causing active sites on enzymes to bind with pulegone instead of the

Hydrogenation (4,071 words) [view diff] exact match in snippet view article find links to article

while nitriles are readily synthesized from cyanide and a suitable electrophile. For example, isophorone diamine, a precursor to the polyurethane monomer

GCLM (942 words) [view diff] exact match in snippet view article find links to article

(2005). "Human glutamate cysteine ligase gene regulation through the electrophile response element". Free Radic. Biol. Med. 37 (8): 1152–9. doi:10.1016/j

Bicyclobutane (712 words) [view diff] exact match in snippet view article find links to article

(2020-10-28). "Bicyclobutane Carboxylic Amide as a Cysteine-Directed Strained Electrophile for Selective Targeting of Proteins". Journal of the American Chemical

Nitro-Mannich reaction (2,892 words) [view diff] exact match in snippet view article find links to article

activation of the nucleophile (via deprotonation by the Brønsted base) and electrophile (via H-bond donation), thus allowing the development of novel enantioselective

Donna Nelson (4,475 words) [view diff] exact match in snippet view article find links to article

Publishers, Inc. Sudbury, MA, 1997. Nelson, Donna J.; Nucleophile / Electrophile Reaction Guide for Organic Chemistry Archived 2008-10-12 at the Wayback

GCLC (1,017 words) [view diff] exact match in snippet view article find links to article

2004). "Human glutamate cysteine ligase gene regulation through the electrophile response element". Free Radical Biology & Medicine. 37 (8): 1152–9. doi:10

Lewis acid catalysis (5,017 words) [view diff] exact match in snippet view article find links to article

there is evidence that the protonated acylium dication is the active electrophile that undergoes subsequent electrophilic aromatic substitution. Important

Procyanidin C2 (1,177 words) [view diff] exact match in snippet view article find links to article

equimolar amount of dimeric catechin nucleophile and monomeric catechin electrophile catalyzed by AgOTf or AgBF4. The coupled product can be transformed into

Acetaldehyde (5,159 words) [view diff] exact match in snippet view article find links to article

precursor to carboxylic acids in the atmosphere. Acetaldehyde is a common electrophile in organic synthesis. In addition reactions acetaldehyde is prochiral

Boranylium ions (2,860 words) [view diff] exact match in snippet view article find links to article

trans-hydroboration with a variety of arylacetylene substrates using a borenium ion electrophile and B(C6F5)3 as a catalyst. Borenium ions have been shown to form ionic

Bromine (7,600 words) [view diff] exact match in snippet view article find links to article

of the easy oxidation of bromide to the equivalent of Br+, a potent electrophile. The enzyme bromoperoxidase catalyzes this reaction. The oceans are estimated

Gel electrophoresis (5,057 words) [view diff] exact match in snippet view article find links to article

phosphate group is released and replaced by an alcohol group from water. The electrophile 4- chloro-2-2 methylbenzenediazonium (Fast Red TR Diazonium salt) displaces

Benzene (9,419 words) [view diff] exact match in snippet view article find links to article

nitration, benzene reacts with nitronium ions (NO2+), which is a strong electrophile produced by combining sulfuric and nitric acids. Nitrobenzene is the

Advanced oxidation process (2,368 words) [view diff] exact match in snippet view article find links to article

essence, ·OH is a radical species and should behave like a highly reactive electrophile. Thus two type of initial attacks are supposed to be Hydrogen Abstraction

Polyvinyl nitrate (1,330 words) [view diff] exact match in snippet view article find links to article

Aromatic Hydrocarbons in Purified Acetic Anhydride, Identification of the Electrophile". J. Chem. Soc., Perkin Trans. 2 (10): 1361–1366. Kazemi, Ayyub; Hayaty

Nitrogen (12,188 words) [view diff] exact match in snippet view article find links to article

acid, nitric acid is protonated to form nitronium, which can act as an electrophile for aromatic nitration: HNO3 + 2 H2SO4 ⇌ NO+ 2 + H3O+ + 2 HSO− 4 The

Bisoxazoline ligand (2,222 words) [view diff] exact match in snippet view article find links to article

square pyramidal complex. A study using (benzyloxy)acetaldehyde as the electrophile showed that the stereochemical outcome is consistent with the carbonyl

Carbocation (5,038 words) [view diff] exact match in snippet view article find links to article

uncommon intermediates. They can be generated by the ionization of a vinyl electrophile, provided the leaving group is sufficiently good (e.g., TfO−, IPh, or

Small Maf (3,041 words) [view diff] exact match in snippet view article find links to article

(Fig. 3). The latter DNA sequences have been recognized as antioxidant/electrophile response elements or NF-E2-binding motifs, to which Nrf2-sMaf heterodimers

Reactive aldehyde species (1,437 words) [view diff] exact match in snippet view article find links to article

particularly in proteins. Following threshold amounts of binding to the electrophile-responsive proteome, RASP modify protein function, as has been described

Turbo-Hauser bases (1,020 words) [view diff] exact match in snippet view article find links to article

and low temperatures. The resulting reagent is then quenched with an electrophile. iPr2NMgCl·LiCl and TMPMgCl·LiCl react differently. The TMP-Turbo-Hauser

Iodine (11,802 words) [view diff] exact match in snippet view article find links to article

heterolytic fission of the I–Cl bond occurs and I+ attacks phenol as an electrophile. However, iodine monobromide tends to brominate phenol even in carbon

Organolithium reagent (5,971 words) [view diff] exact match in snippet view article find links to article

possible for the product cyclic organolithium species to react with electrophiles, whereas it is often difficult to trap a radical intermediate of the

Vinyl cation (4,567 words) [view diff] exact match in snippet view article find links to article

can be achieved in the reaction of electrophiles with alkynes or allenes. In these reactions, a positive electrophile attacks one of the unsaturated carbons

Cystine/glutamate transporter (3,381 words) [view diff] exact match in snippet view article find links to article

Maebara K, Wang H, Tamba M, Itoh K, Yamamoto M, Bannai S (November 2002). "Electrophile response element-mediated induction of the cystine/glutamate exchange

Dichapetalum cymosum (1,608 words) [view diff] exact match in snippet view article find links to article

Organofluorine Compounds: Use of Nonracemic Fluoroiodoacetic Acid as a Practical Electrophile and Its Application to the Synthesis of Monofluoro Hydroxyethylene Dipeptide

CUL3 (2,387 words) [view diff] exact match in snippet view article find links to article

Freeman ML (March 2008). "Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3". Chemical Research in Toxicology

Decay technique (2,072 words) [view diff] exact match in snippet view article find links to article

tert-butyl ions with arenes. Remarkable selectivity of a gaseous, charged electrophile". Journal of the American Chemical Society, volume 95, issue 18, pages

Dynamic kinetic resolution in asymmetric synthesis (1,466 words) [view diff] exact match in snippet view article find links to article

addition over 1,2 addition, with the alkene being a softer more polarizable electrophile. Again, BINAP became the ligand of choice due to its steric selectivity

Reductions with metal alkoxyaluminium hydrides (1,747 words) [view diff] exact match in snippet view article find links to article

this reagent, affording functionalized products after quenching with an electrophile. Functional groups containing heteroatoms other than oxygen may also

Living polymerization (4,362 words) [view diff] exact match in snippet view article find links to article

N-vinylcarbazole. The initiators are binary systems consisting of an electrophile and a Lewis acid. The method was developed around 1980 with contributions

Song Lin (chemist) (1,204 words) [view diff] exact match in snippet view article

Kimberly A.; Lin, Song (April 2022). "Electrochemically driven cross-electrophile coupling of alkyl halides". Nature. 604 (7905): 292–297. Bibcode:2022Natur

Kay Brummond (1,567 words) [view diff] exact match in snippet view article find links to article

"Synthesis of Guaianolide Analogues with a Tunable α-Methylene−γ-lactam Electrophile and Correlating Bioactivity with Thiol Reactivity". J. Med. Chem. 2020

Alkali metal (23,385 words) [view diff] exact match in snippet view article find links to article

electrophilic substitution to give the desired aldehyde (using H+ as the electrophile) or ketone (using an alkyl halide) product.: 105 LiR + Ni ( CO )

Crossover experiment (chemistry) (3,878 words) [view diff] exact match in snippet view article

anion acts as a nucleophile and a methyl (arenesulfonate) serves as an electrophile were known to occur, but it was proposed that they could proceed either

Activation of cyclopropanes by transition metals (2,115 words) [view diff] exact match in snippet view article find links to article

adduct of this complex was characterized by X-ray crystallography. The electrophile Cp*Ir(PMe3)(Me)OTf reacts with cyclopropane to give the allyl complex:

Iodine compounds (3,547 words) [view diff] exact match in snippet view article find links to article

heterolytic fission of the I–Cl bond occurs and I+ attacks phenol as an electrophile. However, iodine monobromide tends to brominate phenol even in tetrachloromethane

Kedarcidin (2,705 words) [view diff] exact match in snippet view article find links to article

First, a Sonogashira coupling was carried out between a bromovinyl electrophile and alkynyl nucleophile; ring closure to give a cyclic triyne was then

Nitrogen compounds (4,297 words) [view diff] exact match in snippet view article find links to article

acid, nitric acid is protonated to form nitronium, which can act as an electrophile for aromatic nitration: HNO3 + 2 H2SO4 ⇌ NO+ 2 + H3O+ + 2 HSO− 4 The

John A. Gladysz (3,004 words) [view diff] exact match in snippet view article find links to article

November 2020. Wong, Wai-Kwok; Tam, Wilson; Gladysz, J. A. (August 1979). "Electrophile-induced disproportionation of the neutral formyl". Journal of the American

Magnesium compounds (1,412 words) [view diff] exact match in snippet view article find links to article

is a commonly used desiccant and can also be used as a Lewis acid or electrophile activator. Magnesium perbromate can also crystallize out of the solution

Jacob Hooker (2,574 words) [view diff] exact match in snippet view article find links to article

reactions, most aptly described as a switch from a nucleophile to an electrophile. In a separate and subsequent advance, this unconventional mindset led

Diallyl carbonate (1,310 words) [view diff] exact match in snippet view article find links to article

process can be run in a single reactor. Phosgene is a highly reactive electrophile. It reacts easily with allyl alcohol. A base is often used to neutralize

Ketenyl anion (2,090 words) [view diff] exact match in snippet view article find links to article

dimerization before synthesizing a target product. In ylide-ketenyl anion, electrophile can be substituted in exchange of metal to functionalize the ketene moiety