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Longer titles found: Farnesyltransferase inhibitor (view), Farnesyl-diphosphate farnesyltransferase (view), Farnesyl-diphosphate farnesyltransferase 1 (view)

searching for Farnesyltransferase 18 found (56 total)

alternate case: farnesyltransferase

FNTA (1,005 words) [view diff] exact match in snippet view article find links to article

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha is an enzyme that in humans is encoded by the FNTA gene. Prenyltransferases

FNTB (868 words) [view diff] exact match in snippet view article find links to article

Protein farnesyltransferase subunit beta is an enzyme that in humans is encoded by the FNTB gene. GRCm38: Ensembl release 89: ENSMUSG00000033373 – Ensembl

Geranylgeranylation (253 words) [view diff] exact match in snippet view article find links to article

onto the C-terminal consensus sequence CAAL (somewhat similar to farnesyltransferase reactions), where C=cysteine, A=any aliphatic amino acid, and L=leucine

RHOB (1,246 words) [view diff] exact match in snippet view article find links to article

alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors". Molecular and Cellular Biology. 20 (16): 6105–13. doi:10

Channing Der (745 words) [view diff] exact match in snippet view article find links to article

prompted intense pharmaceutical industry pursuit of inhibitors of the farnesyltransferase enzyme that catalyzes this lipid modification on RAS and other proteins

Michael Stuart Brown (3,286 words) [view diff] exact match in snippet view article find links to article

Reiss Y, Casey PJ, Brown MS, Goldstein JL (May 1991). "Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit". Cell

Large granular lymphocytic leukemia (1,539 words) [view diff] exact match in snippet view article find links to article

Sokol L, Chen X, et al. (December 2008). "Clinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with

Patrick J. Casey (980 words) [view diff] exact match in snippet view article find links to article

, Casey, P.J. & Beese, L.S. (1997) Crystal structure of protein farnesyltransferase at 2.25 Å resolution. Science 275:1800-1804. Meigs, T.E, Fields,

RRAS (1,142 words) [view diff] exact match in snippet view article find links to article

Lynch MJ, Weinmann R, Seizinger BR, Der CJ, Barbacid M (1995). "Farnesyltransferase inhibitors are inhibitors of Ras but not R-Ras2/TC21, transformation"

Age of onset (1,421 words) [view diff] exact match in snippet view article find links to article

D; Sebti, Said M; Lubet, Ronald A; You, Ming (September 2003). "Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice

CEFIP (1,678 words) [view diff] exact match in snippet view article find links to article

Syndrome 3 and Abdominal Obesity-Metabolic Syndrome FNTA Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha Helps regulate neuromuscular

Triciribine (1,237 words) [view diff] exact match in snippet view article find links to article

Fulp WJ, Coppola D, Hamilton AD, et al. (May 2011). "Combination of farnesyltransferase and Akt inhibitors is synergistic in breast cancer cells and causes

Guard cell (3,442 words) [view diff] exact match in snippet view article find links to article

Ghassemian M, Kwak CM, McCourt P, & Schroeder JI (1998) Role of farnesyltransferase in ABA regulation of guard cell anion channels and plant water loss

Optical rotation (4,889 words) [view diff] exact match in snippet view article find links to article

are used infrequently in English. Sebti; Hamilton, eds. (2001). Farnesyltransferase inhibitors in cancer therapy. p. 126. ISBN 9780896036291. Retrieved

Juvenile myelomonocytic leukemia (2,981 words) [view diff] exact match in snippet view article find links to article

Brigitte; Emanuel, Peter D. (2005-11-16). "Phase II Window Study of the Farnesyltransferase Inhibitor R115777 (Zarnestra®) in Untreated Juvenile Myelomonocytic

Fungal isolate (966 words) [view diff] exact match in snippet view article find links to article

anticancer derivatives of illudin S. Clavaric acid is a reversible farnesyltransferase inhibitor. Inonotus obliquus creates betulinic acid precursor betulin

Elizabeth Nabel (1,907 words) [view diff] exact match in snippet view article find links to article

Avallone H, Kolodgie FD, Virmani R, Nabel EG, Collins FS (2008). "A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular

Said Sebti (927 words) [view diff] exact match in snippet view article find links to article

natural product called marinopyrrole A. FTase/GGTase. Sebti's work on farnesyltransferase and geranylgeranyltransferase led to the development of the drug