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Longer titles found: Gag-onc fusion protein (view), Membrane fusion protein (view), N-ethylmaleimide sensitive fusion protein (view), Vacuolar fusion protein Mon1 (view), Tpr-met fusion protein (view)

searching for Fusion protein 288 found (480 total)

alternate case: fusion protein

Factor IX (1,943 words) [view diff] exact match in snippet view article find links to article

IX [recombinant] (Idelvion) coagulation factor IX (recombinant), Fc fusion protein (Alprolix) coagulation factor IX [recombinant] (Ixinity) coagulation

growth factors. JAK2 phosphorylates the BCR-ABL fusion protein at Y177 and stabilizes the fusion protein, strengthening tumorigenic cell signaling. JAK2

is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein

hallmarks of M2 subtype acute myeloid leukemia is the formation of a fusion protein, AML1-ETO or RUNX1-RUNX1T1, due to a translocation of chromosome 8 to

DNA polymerase domain. Homologs of this unique polymerase-helicase fusion protein are widespread in Polinton-Like Viruses (PLV). Based on the phylogenetic

A polyhistidine-tag, best known by the trademarked name His-tag, is an amino acid motif in proteins that typically consists of at least six histidine (His)

evaluating the immunogenicity and safety of a recombinant novel coronavirus fusion protein vaccine in healthy people]. chictr.org.cn (in Chinese). Chinese Clinical

have been identified as essential components of the synaptic vesicle fusion protein complex and are crucial for the regulated exocytosis of neurons and

there are a few genetic recombination events that occurs to cause the fusion protein to be synthesized. In order to have the PAX3-FOXO1 fusion there needs

PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. P2Y receptor

Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein FUBI at the N-terminus and

Hepadnaviral S Fusion Protein (HBV-S Protein) Family 1.G.7 The Reovirus FAST Fusion Protein (R-FAST) Family 1.G.8 The Arenavirus Fusion Protein (AV-FP) Family

nodes, brain, skull, and bones. It is characterized by the EWS-WT1 fusion protein. The tumor is classified as a soft tissue sarcoma and a small round

Efmoroctocog alfa is a recombinant human coagulation factor VIII, Fc fusion protein (rFVIIIFc). It is produced by recombinant DNA technology in a human

the Basis of a Novel Enzyme-Linked Immunosorbent Assay Utilizing hMPV Fusion Protein Expressed in Recombinant Vesicular Stomatitis Virus". Journal of Clinical

of the stop codon at the gag-pol junction producing the gag and pol fusion protein in certain retroviruses. Retroviruses whose gag and pol genes are in

Izumo sperm-egg fusion protein 1 (Sperm-specific protein izumo) is encoded in humans by the IZUMO1 gene. In mammalian fertilisation, IZUMO1 binds to its

resistant to the more reducing cytosolic environment, or expression as a fusion protein with maltose binding protein or other stable intracellular proteins

protein 48 (CDC48), VCP-like ATPase and N-ethylmaleimide sensitive fusion protein. It is a substrate recognition domain which binds polypeptides, prevents

Asunercept (INN; development codes APG101 and CAN008) is a soluble CD95-Fc fusion protein which is in clinical development for the treatment of glioblastoma multiforme

The hisB gene, found in the enterobacteria (such as E. coli), in Campylobacter jejuni and in Xylella/Xanthomonas encodes a protein involved in catalysis

F protein‑directed fusion inhibitor that is designed to bind to the fusion protein on the surface of the RSV virus. The most common side effects are rash

has started in Mid-September to Mid-November. Palivizumab targets the fusion protein of RSV, inhibiting its entry into the cell and thereby preventing infection

proliferation of their parent cells. The tyrosine kinase of the ETV6-NTRK3 fusion protein is dysfunctional in that it is continuously active in phosphorylating

PMC 1988922. PMID 17440052. Rubbert-Roth, A. (2010). "TRU-015, a fusion protein derived from an anti-CD20 antibody, for the treatment of rheumatoid

BRD4 or BRD3, which creates a chimeric gene that encodes the BRD-NUT fusion protein. The remaining cases, the fusion of NUTM1 is to an unknown partner gene

downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome

The protein's C-terminus contains the C-terminus of the TrkC. The fusion protein lacks transcription regulating activity but has dysregulated, i.e. continuously

proteins; nucleoprotein (N), phosphoprotein (P), matrix protein (M), fusion protein (F), attachment glycoprotein (G), and the large protein or RNA polymerase

classification of Tumors of Soft Tissue suggests that USP6-containing fusion protein-associated tumors are typically benign and usually self-limited in their

Shimizu K, Nomura N, Hayashi Y, Ohki M (1998). "The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1"

McConnell MJ, Polinger A, Hiebert SW, Licht JD (2000). "AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the

Shimizu K, Nomura N, Hayashi Y, Ohki M (1998). "The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1"

protein MAD2B, which suggests that the dominant-negative effect of the fusion protein with TFE3 may lead to a mitotic checkpoint defect. Alternatively spliced

coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas". Cancer Research

the E2-type has a major monooxygenase (StyA1) which is supported by fusion protein of a monooxygenase and reductase (StyA2B). The latter one is the source

monoclonal antibody targeting tumor cells and an IL-15/IL-15 receptor fusion protein (IL-15RF) promoting cytokine-independent persistence. A more efficient

ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N-terminus and ribosomal protein L40

McConnell MJ, Polinger A, Hiebert SW, Licht JD (Dec 2000). "AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the

TG103 is an experimental GLP-1 receptor agonist and Fc fusion protein combination, developed by CSPC Pharmaceutical Group. Jin, Jiangli; Cui, Gang; Mi

mature batroxobin. The fusion protein which was obtained was insoluble and was easily purified. After cleaving the fusion protein, the recombinant batroxobin

coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas". Cancer Research

transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal

alfa is an experimental drug that works as an interleukin-2 "mutein Fc fusion protein that preferentially binds the high-affinity IL-2 receptor alpha chain

characterized by the spike-like projections of two viral proteins, the fusion protein (F) and hemagglutinin-neuraminidase (Hn) protein. However, these protein

system components include: an ABC transporter (TC# 3.A.1), a membrane fusion protein (MFP; TC# 8.A.1), and an outer membrane protein (OMF; TC# 1.B.17). The

2-(1-Alkylaminoalkyl)pyrazolo[1,5-a]pyrimidines as New Respiratory Syncytial Virus Fusion Protein Inhibitors". Chemical & Pharmaceutical Bulletin. 68 (4): 345–362. doi:10

cancer patients. Mechanistically, research has shown that TIGIT-Fc fusion protein could interact with PVR on dendritic cells and increase its IL-10 secretion

Gonzalez N, et al. (2003). "Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor

Over 90% of thyroid tumors arise from follicular thyroid cells. A fusion protein, PAX8-PPAR-γ, is implicated in some follicular thyroid carcinomas and

protein on the outer portion of the membrane, and SmeD, a membrane fusion protein. On general purpose media and no selectors, the genes for MDR pumps

that expresses a PAX3-FOXO1 fusion transcript encoding a PAX3-FOXO1 fusion protein. PAX3 and FOXO1 encode transcription factors, and the translocation

Gonzalez N, et al. (2003). "Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor

a fusion protein of LacZ in mice, exploiting β-galactosidase's tendency to oligomerise to suggest a potential role for oligomericity in MLL fusion protein

vesicle endocytosis negative regulation of membrane invagination vesicle fusion protein homotetramerization negative regulation of clathrin-dependent endocytosis

develop a drug for hemophilia B, a long-lasting recombinant factor IX Fc fusion protein candidate, rFIXFc. This partnership was extended the following year

Strep-tag purification cycle, the cell lysate containing Strep-tag fusion protein is applied to a column with immobilized Strep-Tactin (step 1). After

may not compete with the fusion-protein for its binding partner. Binding between the third protein and the other fusion protein will interrupt the formation

mutant (IL-15N72D) and a dimeric IL-15 receptor α sushi domain-IgG1 Fc fusion protein. ALT-803 was given fast track status by the FDA in 2017 and at that

mating. As such, display of a protein via Aga2p likely projects the fusion protein from the cell surface, minimizing potential interactions with other

Monoclonal antibody Type ? Source Human Target respiratory syncytial virus fusion protein Clinical data Other names REGN2222 ATC code none Identifiers CAS Number

(helicase), and Rdrp (RNA-dependent RNA polymerase). The Pvx domain is a fusion protein consisting of the Plp, V, and X domains. The O3 protein is encoded by

PMID 15489334. Bai X, Chen X, Fen Z, et al. (2005). "Expression of EGFP/SDCT1 fusion protein, subcellular localization signal analysis, tissue distribution and

for the respiratory syncytial virus (RSV) fusion protein. Interference with the nucleolin–RSV fusion protein interaction has been shown to be therapeutic

and catenin family of cell adhesion molecules as demonstrated by GST-fusion protein pull-down assays using brain homogenate. Using this technique, the authors

inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein". Blood. 103 (4): 1445–53. doi:10.1182/blood-2003-07-2452. hdl:10722/48499

C, Lessard M, Berger R, Ghysdael J, Bernard OA (1997). "A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia". Science. 278 (5341):

as a Trojan horse-enzyme fusion protein that crosses the BBB. The first clinical trials of the new Trojan horse fusion protein technology will treat the

Christopher M (Dec 2002). "Utilization of a novel recombinant myoglobin fusion protein expression system to characterize the tissue inhibitor of metalloproteinase

contains a proprietary UBITh1 peptide derived from the measles virus fusion protein, CpG oligonucleotides, and aluminum phosphate adjuvant to improve the

step at least for 5 times with the amplified labeled DNA sample and fusion protein. Sequence the DNA: After final step of selection and electrophoresis

Gustafsson JA, Spyrou G, Miranda-Vizuete A (Dec 2001). "Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains

internalized thyrotropin-releasing hormone receptors monitored with a timer fusion protein". Endocrinology. 145 (7): 3095–100. doi:10.1210/en.2004-0304. PMID 15117874

Ip NY (2006). "Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis"

specifically target BCR-ABL, the constitutively activated tyrosine kinase fusion protein caused by the Philadelphia chromosome translocation. Despite the move

1". Yang L, Embree LJ, Hickstein DD (May 2000). "TLS-ERG leukemia fusion protein inhibits RNA splicing mediated by serine-arginine proteins". Mol. Cell

"Wnt-independent activation of beta-catenin mediated by a Dkk1-Fz5 fusion protein". Biochem. Biophys. Res. Commun. 328 (2): 533–9. doi:10.1016/j.bbrc

commercialization of ADUHELM. ALPROLIX™ [Coagulation Factor IX (Recombinant), Fc Fusion Protein] Control and prevention of bleeding episodes, perioperative management

the paramyxovirus fusion protein, which causes the virus membrane to fuse with the cell surface membrane. Studies on the fusion protein were applicable

trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein". Molecular and Cellular Biology. 14 (5): 3403–13. doi:10.1128/mcb.14

chromosome X causes the presence of an SS18-SSX fusion gene. The resulting fusion protein brings together the transcriptional activating domain of SS18 and the

extracellular domain of the activin type 2 receptor expressed as a recombinant fusion protein with immunoglobulin Fc domain (ACTRIIA-Fc). It is given by subcutaneous

changes made, in case something went wrong. CRISPRoff is a dead Cas9 fusion protein that can be used to heritably silence the gene expression of "most genes"

protein is engineered to include p65 and HSF1 proteins. The MS2-p65-HSF1 fusion protein interacts with the dCas9-VP64 to recruit more transcriptional factors

structure and functionality is most closely resembling a class II membrane fusion protein compared to any other class. The pH sensing feature in the Gc protein

tabacum expressing a betaine aldehyde dehydrogenase/choline dehydrogenase fusion protein". Biotechnol. Prog. 18 (6): 1176–82. doi:10.1021/bp020057k. PMID 12467448

cerebellum. A study done in Seattle, USA, established the presence of the fusion protein product of the SLC39A9-PLEKHD1 gene to be present in 124 cases of schizophrenia

protein is not completely understood, but WDCP has been identified in a fusion protein with anaplastic lymphoma kinase found in colorectal cancer. WDCP has

myeloid and lymphocyte precursor cells. In consequence, the RBM15-MKL1 fusion protein acts in an unregulated fashion to suppress MKL1 targeted genes while

upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein consisting of sequence sharing identity with each individual gene product

Platforms Development of Antibody and PK, and ADA Assays for a Cystine Knot Fusion Protein A Rapid, High-Throughput Recombinant Antibody Expression System for

example, removing the part corresponding to the large subunit in a fusion protein PolpTN2 results in a slower enzyme with reverse transcriptase activity

nucleocapsid core, it organizes and maintains virion structure F – the fusion protein projects from the envelope surface as a trimer, and mediates cell entry

pathways. The FIP1L1 component of FIP1L1-PDGFRA is required for the fusion protein to activate STAT4 and protein kinase B. The age-adjusted incidence of

hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein". The EMBO Journal. 21 (21): 5711–20. doi:10.1093/emboj/cdf565. PMC 131062

inactivation by codisplay of decay accelerating factor (DAF) or of a GP64-DAF fusion protein". Mol Ther. 11 (4): 645–51. doi:10.1016/j.ymthe.2004.12.002. PMID 15771967

"Structural characterization of the human respiratory syncytial virus fusion protein core". Proceedings of the National Academy of Sciences. 97 (26): 14172–14177

Clinical Trial 071163 - A Phase I/II study of A-dmDT390-bisFv(UCHT1) Fusion Protein in Patients with Cutaneous T-Cell Lymphoma "Clinical Trials: Identification

development of NTRK3-directed tyrosine kinase inhibitors to treat ETV6-NTRK3 fusion protein associated malignancies. Three clinical trials are in the recruitment

encoded by gene P; a V protein, a matrix protein, encoded by M; a fusion protein, encoded by F; and a large polymerase subunit, encoded by L. In addition

segment that encodes its major coat protein, Gag (76 kDa) and a Gag-Pol fusion protein (180 kDa) formed by a -1 ribosomal frameshift. L-A can support the replication

Pheromone-dependent signal transduction in conjugation with cellular fusion Protein dephosphorylation tRNA splicing via. Endonucleolytic cleavage and ligation

Munirathinam G, Reddy MV, Kalyanasundaram R (March 2013). "Multivalent fusion protein vaccine for lymphatic filariasis". Vaccine. 31 (12): 1616–22. doi:10

Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6". The Journal

Lipinski M, Harel-Bellan A (1996). "SRE elements are binding sites for the fusion protein EWS-FLI-1". Nucleic Acids Res. 24 (6): 1052–8. doi:10.1093/nar/24.6

Sadek CM, Damdimopoulos AE, Pelto-Huikko M, et al. (2002). "Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains

an improvement in the hearing loss. Rilonacept (Arcalyst) a dimeric fusion protein for the treatment of CAPS. Canakinumab, a monoclonal antibody against

Enteropeptidase's specificity makes it an ideal tool in biochemical applications; a fusion protein containing a C-terminal affinity tag (such as poly-His) linked by this

operon includes: CzcA (the RND family specific protein), the membrane fusion protein (MFP) CzcB, and the outer membrane factor protein (OMF) CzcC, all of

activation by priming virus's Spike protein to show the protein named "fusion protein" (TMPRSS2 activate SARS-CoV-2 fusion). Exogenous snake venom serine

co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein". The Biochemical Journal. 320. 320 ( Pt 2) (2): 429–36. doi:10.1042/bj3200429

for autoimmunity and B cell malignancies via atacicept, a recombinant fusion protein that binds the TACI ligands BAFF and APRIL. TNFRSF13B has been shown

the streptococcal C5a peptidase using a C5a-green fluorescent protein fusion protein substrate". Journal of Bacteriology. 182 (11): 3254–8. doi:10.1128/jb

methylation sites near the protein. Researchers were guided by the fusion protein strategy of DamID to create a method for site-specific labeling of protein

properties of the novel basal insulin Fc (insulin efsitora alfa), an insulin fusion protein in development for once-weekly dosing for the treatment of patients

PMID 22484672. Chen, Xiaoying; Zaro, Jennica; Shen, Wei-Chiang (2013-10-15). "Fusion Protein Linkers: Property, Design and Functionality". Advanced Drug Delivery

Lymantria dispar (LdMNPV) is suggested to be an ancestral envelope fusion protein which has been replaced by non-orthologous gene replacement with gp64

ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein". Blood. 98 (1): 201–9. doi:10.1182/blood.V98.1.201. PMID 11418481.

Jesse; Krattinger, Simon G. (2023-05-22). "An unusual tandem kinase fusion protein confers leaf rust resistance in wheat". Nature Genetics. 55 (6): 914–920

(May 2009). "Identification of PpoA from Aspergillus nidulans as a fusion protein of a fatty acid heme dioxygenase/peroxidase and a cytochrome P450".

upstream gene (MASK) generates a transcript (MASK-BP3) which encodes a fusion protein composed of the MASK protein sequence for the majority of the protein

cleave the fusion protein, BCR-ABL, which prevents the drug Gleevec (imatinib) from binding to the cancer cells. Cleaving the fusion protein reduced the

Harel-Bellan A (March 1996). "SRE elements are binding sites for the fusion protein EWS-FLI-1". Nucleic Acids Research. 24 (6): 1052–8. doi:10.1093/nar/24

are associated with a poorer prognosis than fusion-negative RMS. The fusion protein presents a potential therapeutic target, and in recent years more research

during replication. Embedded within the lipid membrane are spikes of F (fusion) protein trimers and G (attachment) protein tetramers. The function of the G

complex that contains the MS2’s RNA-binding sequence copies. The MS2-GFP fusion protein was expressed by transferring it to a cell with a plasmid (Robert Singer’s

viral or cellular proteins; however, p15 has been found to be the cell fusion protein in BRV. Avian orthoreovruses The Avian orthoreovirus has a similar structure

acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein". Blood. 92 (7): 2244–51. PMID 9746761. Schneider SM, Pritchard SM,

of zearalenone using recombinant peptidomimetic Gaussia luciferase fusion protein". Mikrochimica Acta. 187 (10): 547. doi:10.1007/s00604-020-04538-7.

antibodies, (iii) a recombinant truncated form of PSGL-1 immunoglobulin fusion protein, and (iv) small-molecule inhibitors of selectins. Most selectin blockers

collagen gene transcription is differentially regulated by EWS/ERG sarcoma fusion protein and wild-type ERG". The Journal of Biological Chemistry. 278 (13): 11369–75

infect archaea and which have a viral envelope that contains a membrane fusion protein Phylum: Saleviricota Class: Huolimaviricetes Order: Haloruvirales Family:

blood product is sent to a production facility and incubated with a fusion protein (PA2024) consisting of two parts: The antigen prostatic acid phosphatase

membrane association as well because they allow Src to associate with fusion protein constructs. Myristoylation and fusion proteins work together to localize

calmodulin-binding peptide M13 and EGFP. The DNA encoding cameleon fusion protein must be either stably or transiently introduced into the cell of interest

co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein". The Biochemical Journal. 320 (Pt 2): 429–36. doi:10.1042/bj3200429

co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein". The Biochemical Journal. 320. 320 (2): 429–36. doi:10.1042/bj3200429

characterization of the carboxyl-domain of human hexokinase type III expressed as fusion protein". Molecular and Cellular Biochemistry. 155 (1): 23–9. doi:10.1007/BF00714329

ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein". Blood. 98 (1): 201–9. doi:10.1182/blood.V98.1.201. PMID 11418481.

downstream gene (EIF4EBP3) generates a transcript (MASK-BP3) which encodes a fusion protein composed of the MASK protein sequence for the majority of the protein

sites. This technology is called donor recruitment and relies on a fusion protein that contains one domain recruited to DNA breaks and another domain

the NIH in the U.S. Technically, CAT-3888 is an anti-CD22 immunotoxin fusion protein between a murine anti-CD22 disulfide-linked Fv (dsFv) antibody fragment

decreased fibrosis and improved regeneration. ACE-083, a follistatin-based fusion protein, was investigated for treatment focal or asymmetric myopathies. Intramuscular

myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated

‘fusion gene’ that expresses an abnormal mRNA resulting in synthesis of a fusion protein variant of TAZ that is always turned on. This form of TAZ always resides

center sulfhydryls: site-directed mutagenesis of a new recombinant fusion protein". Biochemistry. 39 (32): 9687–97. doi:10.1021/bi000274z. PMID 10933785

biomarkers are genes such as ER, PR and HER2/neu in breast cancer, BCR-ABL fusion protein in chronic myeloid leukaemia, c-KIT mutations in GIST tumours and EGFR1

retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha

as kidney, ovary and liver. EHD3 (expressed as a green fluorescent fusion protein) was localized in endocytic vesicles, mostly in recycling vesicles,

between miR-203 and ABL1 levels (sometimes expressed as the BCR-ABL1 fusion protein). Supporting its role as a tumour suppressor, it has also been found

hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK–APRIL fusion protein". EMBO J. 21 (21): 5711–20. doi:10.1093/emboj/cdf565. PMC 131062. PMID 12411489

endoplasmic reticulum lumen Biological process endoplasmic reticulum membrane fusion protein K48-linked deubiquitination Golgi organization protein ubiquitination

(publ). "Altuviiio (antihemophilic factor- recombinant, fc-vwf-xten fusion protein-ehtl kit". DailyMed. 31 March 2023. Retrieved 7 May 2023. "Altuviiio"

membranes together. The alphaviral glycoprotein E1 is a class II viral fusion protein, which is structurally different from the class I fusion proteins found

Professionals". Drugs.com. "Antihemophilic Factor (recombinant), Fc Fusion Protein Monograph for Professionals". Drugs.com. "Antihemophilic Factor (recombinant)

Mauricio Martins. "TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein

Overall CM (December 2002). "Utilization of a novel recombinant myoglobin fusion protein expression system to characterize the tissue inhibitor of metalloproteinase

strongly phosphorylated after MHC II stimulation. Studies performed with fusion protein CD25-SCIMP showed its ability to induce calcium release and Erk phosphorylation

et al. (2016-08-30). "The dual effect of a ferredoxin-hydrogenase fusion protein in vivo: successful divergence of the photosynthetic electron flux towards

polymerase is not soluble enough to be produced in large quantities, and a fusion protein constructed from the replicase and the two EF subunits is usually used

present HLA-associated immunogenic peptides derived from the BCR-ABL b3a2 fusion protein" (PDF). Blood. 98 (10): 2887–2893. doi:10.1182/blood.V98.10.2887. PMID 11698267

encoding nucleoprotein (N), phosphoprotein (P), matrix protein (M),fusion protein (F), […]" second Matrix (M2) "small hydrophobic protein (SH), attachment

Baumann H, Kunapuli P, Tracy E, Cowell JK (May 2003). "The oncogenic fusion protein-tyrosine kinase ZNF198/fibroblast growth factor receptor-1 has signaling

is developing a cancer vaccine targeting MAGE-A3. The vaccine is a fusion protein of MAGE-A3 and Haemophilus influenzae protein D, combined with a proprietary

downregulated. Enforced expression of wild-type NCOA2 but not the LACTB2-NCOA2 fusion protein impaired the pro-tumorigenic phenotypes of CRC cells, whereas knockdown

nuclear localization of phosphatase inhibitor 2-green fluorescent protein fusion protein during S phase of the cell growth cycle". The Journal of Biological

ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein". Blood. 98 (1): 201–9. doi:10.1182/blood.V98.1.201. PMID 11418481.

allogeneic (“off-the-shelf”) cell line engineered to express OX40 ligand fusion protein (OX40L-Fc). OX40 ligand is a key co-stimulator of T cells that augments

Potent, Selective, and Orally Bioavailable Respiratory Syncytial Virus Fusion Protein Inhibitor". Journal of Medicinal Chemistry. 62 (13): 6003–6014. doi:10

multivesicular body protein 3) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. GRCh38:

unfolded fusion protein (TAT) and the membrane through electrostatic interactions, which disrupt the membrane enough to allow the fusion protein to cross

of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein". EMBO J. 20 (24): 7184–96. doi:10.1093/emboj/20.24.7184. PMC 125775

receptor tyrosine kinase (ROS), producing a fusion protein (FIG-ROS). The abnormal FIG-ROS fusion protein has constitutively active kinase activity that

called denileukin diftitox (trade name Ontak), which is a recombinant fusion protein of the human IL-2 ligand and the diphtheria toxin. This drug binds to

Hamamoto T, et al. (1993). "Expression of human metallothionein-II fusion protein in Escherichia coli". Biochem. Int. 28 (3): 451–60. PMID 1339282. Messerle

"Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways". Blood. 99

inv(16)(p13q22) creates the CBFB-MYH11 fusion gene, which encodes the CBFβ-SMMHC fusion protein. The inv(16) is present in all M4Eo subtype AML, representing one of

et al. (December 2002). "Utilization of a novel recombinant myoglobin fusion protein expression system to characterize the tissue inhibitor of metalloproteinase

Cloning and expression of biologically active alpha-galactosidase A as a fusion protein, (1996). Acid sphingomyelinase gene and diagnosis of Niemann-Pick disease

PMID 17016631. Ishida M, Miyamoto M, Naitoh S, et al. (2007). "The SYT-SSX fusion protein down-regulates the cell proliferation regulator COM1 in t(x;18) synovial

mitochondrion nucleus cytoplasm cytosol Biological process mitochondrial fusion protein targeting to mitochondrion response to retinoic acid mitochondrial fission

Lessard M, Berger R, Ghysdael J, Bernard OA (November 1997). "A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia". Science. 278 (5341):

kinases, and the leucine-rich repeat kinases and an oncogenic PKA kinase fusion protein. Zhang's lab applies integrated structural biology (single-particle

of natural killer cell activation positive regulation of macrophage fusion protein stabilization positive regulation of microglial cell mediated cytotoxicity

a tyrosine kinase inhibitor designed specifically for the bcr-abl fusion protein that is characteristic for Philadelphia chromosome-positive leukemias

PMID 15489334. Kwok SC, Liu X, Mangel P, Daskal I (2006). "PTX1(ERGIC2)-VP22 fusion protein upregulates interferon-beta in prostate cancer cell line PC-3". DNA

Fujisaku A, et al. (1990). "Antigenicity of a recombinant Ro (SS-A) fusion protein". Arthritis Rheum. 33 (1): 102–6. doi:10.1002/art.1780330114. PMID 1689160

codon is absent in the insert. This can lead to the expression of a fusion protein that has a functional LacZα if its structure is not disrupted. The correct

oxidative stress-induced cell death positive regulation of mitochondrial fusion protein localization to mitochondrion proteasomal protein catabolic process

spectroscopy in the ultraviolet wavelength region (UV-CD) of MBP-cytochrome b6 fusion protein in different detergent solutions. It shows that the protein in DM, as

Marschalek R (August 2004). "Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology?". Oncogene

Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6". J. Biol. Chem

α1-helix of the actin-binding domain (ABD), exposed in this chimeric fusion protein, is responsible for stabilizing the adherence junctions and creating

one amino acid in the protein it uses to get into host cells. In the fusion protein of the virus and two putative T cell epitopes in the capsid protein

transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein". Mol. Cell. Biol. 18 (6): 3604–11. doi:10.1128/MCB.18.6.3604. PMC 108942

PMID 2734021. Takahashi M, Cooper GM (1987). "ret transforming gene encodes a fusion protein homologous to tyrosine kinases". Mol. Cell. Biol. 7 (4): 1378–85. doi:10

interactor CATS influences the subcellular localization of the leukemogenic fusion protein CALM/AF10". Oncogene. 25 (29): 4099–109. doi:10.1038/sj.onc.1209438

of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein". The EMBO Journal. 20 (24): 7184–96. doi:10.1093/emboj/20.24.7184.

of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein". The EMBO Journal. 20 (24): 7184–96. doi:10.1093/emboj/20.24.7184.

Primary Immune Cells as Determined with a Lethal Factor-β-Lactamase Fusion Protein. PLoS ONE, 4(11), 1–6. doi:10.1371/journal.pone.0007946 Oliva, C., Turnbough

Commission for ELONVA (corifollitropin alfa) a long lasting single injection fusion protein lacking LH activity. Only one injection is required for the first seven

therapeutic setting to produce Fc-glucagon-like peptide 1 (Fc-GLP-1), a fusion protein that helps control blood glucose levels in mammals with Type II Diabetes

generates naturally occurring transcripts (NME1-NME2) which encode a fusion protein consisting of sequence sharing identity with each individual gene product

generates naturally occurring transcripts (NME1-NME2), which encodes a fusion protein consisting of sequence sharing identity with each individual gene product

GFP fusion protein being expressed in Nicotiana benthamiana. The fluorescence is visible by confocal microscopy.

receptor, or keratins. Genetic testing t(2;4)(q35;q31.1): PAX3-MAML3 fusion protein Only a few cases have shown a PAX3-NCOA1 (inv(2)(q35p23)), and the tumor

and ISG15. One additional protein, known as FUBI, is encoded as a fusion protein in the FAU gene, and is proteolytically processed to generate a free

carcinoma (HNSCC). Eftilagimod alpha ("efti" in short) is a soluble LAG-3 fusion protein that activates antigen-presenting cells. It is a 160 kDa protein consisting

Upregulation of the DNA repair protein EYA3 in this tumour is mediated by the fusion protein transcription factor EWS/FLI1, which in turn is via repression of miR-708

(May 2009). "Identification of PpoA from Aspergillus nidulans as a fusion protein of a fatty acid heme dioxygenase/peroxidase and a cytochrome P450".

(April 2017). "Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia". Scientific Reports. 7 (1): 623. Bibcode:2017NatSR

Gene therapy procedures include modifying the zinc fringer nuclease fusion protein, cleaving both ends of the mutation, which in turn removes it from the

inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein". Blood. 103 (4): 1445–53. doi:10.1182/blood-2003-07-2452. hdl:10722/48499

antiangiogenic integrin alphav antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases. Proc Natl Acad Sci U S A 1999;96:1591-6

xenograft models. Recent studies have also shown that Bcr-Abl, the fusion protein responsible for chronic myelogenous leukemia (CML), downregulates PHLPP1

PMID 12477932. Durst KL, Lutterbach B, Kummalue T, et al. (2003). "The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain

bromelain-cleaved ectodomain. Both hemagglutinin and hemagglutinin esterase fusion protein are similar in terms of structure and the folding of individual segments

Romiplostim (trade name Nplate) is a thrombopoiesis stimulating Fc-peptide fusion protein (peptibody) that is administered by subcutaneous injection. Designated

Rubartelli A (September 1995). "Nuclear translocation of an exogenous fusion protein containing HIV Tat requires unfolding". AIDS. 9 (9): 995–1000. doi:10

(October 2007). "Biochemical characterization of a SET and transposase fusion protein, Metnase: its DNA binding and DNA cleavage activity". Biochemistry.

axotomy-induced neuronal apoptosis by extracellular delivery of a Bcl-XL fusion protein". J. Biol. Chem. 276 (49): 46326–32. doi:10.1074/jbc.M108930200. PMID 11574549

"Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways". Blood. 99

dynamin-related proteins and thus demonstrates that at each membrane, a single fusion protein is not sufficient to drive the lipid-mixing step. Instead, this step

Yan, Huimin; Zhong, Maohua (2017). "Second-generation Flagellin-rPAc Fusion Protein, KFD2-rPAc, Shows High Protective Efficacy against Dental Caries with

tRNA-intron lyase, α′2  is composed of two α′ subunits that appear to be a fusion protein made up of two α subunits connected by a linker. The α′2 structure is

Ubiquitination occurs via the BRCA1 fusion protein and is abolished by zinc chelation. The enzyme activity of the fusion protein is dependent on the proper folding

cells was exposed to the pheromone, alpha-factor. Using a Whi5-GFP fusion protein, they tracked the amount of nuclear Whi5 following the addition of alpha-factor

Biological process COPII-coated vesicle budding cell death membrane fusion protein folding in endoplasmic reticulum sphingolipid biosynthetic process endoplasmic

Masuda, K; Setton LA (2007). "Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1

was held in 2007 at Monterey. In 2008, Carol A Mercer created a BHMT fusion protein (GST-BHMT), which showed starvation-induced site-specific fragmentation

Otto H, Barton N, Jahn R (July 1995). "The N-ethylmaleimide-sensitive fusion protein and alpha-SNAP induce a conformational change in syntaxin". The Journal

not been reported against etanercept, a biologic medication that is a fusion protein composed of two TNF-α receptors. The lack of neutralizing antibodies

(Feb 1997). "Identification of two isoforms of the vesicle-membrane fusion protein SNAP-23 in human neutrophils and HL-60 cells". Biochemical and Biophysical

green). If the candidate is in fact a degron, then the abundance of the fusion protein will decrease much faster than that of the unaltered protein. Second

disrupts its interactions with the chaperones, which allows the Cre-ER fusion protein to enter the nucleus and perform recombination on the floxed gene. Additionally

lymphoma (DLBCL) and in other haematological malignancies PML-RARA fusion protein in acute myeloid leukemia recruits histone deacetylases. This leads

lymphoma (DLBCL) and in other haematological malignancies PML-RARA fusion protein in acute myeloid leukemia recruits histone deacetylases. This leads

deferiprone and deferasirox). Luspatercept (ACE-536) is a recombinant fusion protein that is used as a treatment in adults with transfusion dependent beta

simple tool to study membrane interaction events such as membrane fusion, protein localization in the plasma membrane, study ion channels, etc. Lipid

S, Bavari S, Kaplan G (September 2016). "Ebolavirus Glycoprotein Fc Fusion Protein Protects Guinea Pigs against Lethal Challenge". PLOS ONE. 11 (9): e0162446

needed in protein purification. The ELP tags have been used in the fusion protein of intein, so that the aggregates can be isolated without chromatography

Kitabayashi I, Ida K, Morohoshi F, et al. (1998). "The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1"

Raida, Manfred; Burke, Brian (2012-03-19). "A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells". The

visualized in the neural tube of mice engineered to express a SHH::GFP fusion protein to show this graded distribution of SHH during the time of ventral neural

fluorescent tag. She showed that the resulting green fluorescent protein fusion protein behaved the same way the untagged protein. Green fluorescent protein

D.R. (2003) Oncogene 22: 7750-61 'Vav-promoter regulated oncogenic fusion protein NPM-ALK in transgenic mice causes B-cell lymphomas with hyperactive

a single polypeptide. Regardless of which protein comes first, this fusion protein may show similar function. Thus, if a fusion between two proteins occurs

development of the company's lead program SO-C101 (RLI-15) which is a human fusion protein of IL-15 and the high-affinity binding domain of IL-15Ra. It is a novel

acetyltransferase is largely blocked by the blood-brain barrier. PTD-ChAT is a fusion protein made up of both protein transduction domain and choline acetyltransferase;

magnitude.[better source needed] For example, the PTAC system is used for fusion protein expression within the PMAL-C2X expression.[better source needed] de

PMID 15489334. Chan EM, Comer EM, Brown FC, et al. (2005). "AML1-FOG2 fusion protein in myelodysplasia". Blood. 105 (11): 4523–6. doi:10.1182/blood-2004-07-2762

could be artifacts of aggregated proteins that commonly result from fusion protein expression. Characteristics of purinosome bodies were found to be shared

Nishi A, Sato N, Mizukami J, Miyoshi H, Sugita T (2002). "TAK1-TAB1 fusion protein: a novel constitutively active mitogen-activated protein kinase kinase

Baltimore's laboratory at MIT, George Q. Daley demonstrated that a fusion protein called bcr-abl is sufficient to stimulate cell growth and cause chronic

tertiary structure of TMEM81 has been predicted using izumo sperm-egg fusion protein 1 as a template. The image on the right depicts a model of residues

acquisition from RNA mediated by a natural reverse transcriptase-Cas1 fusion protein associated with a type III-D CRISPR-Cas system in Vibrio vulnificus

Ribas JC, Wickner RB (April 1998). "The Gag domain of the Gag-Pol fusion protein directs incorporation into the L-A double-stranded RNA viral particles

in HeLa cells during cell division as revealed by a GFP-calmodulin fusion protein technique" (PDF). Journal of Cell Science. 112 ( Pt 10) (10): 1567–1577

trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate". The

S2CID 23901646. Baker RT, Board PG (1991). "The human ubiquitin-52 amino acid fusion protein gene shares several structural features with mammalian ribosomal protein

procedure. The cells are incubated ex vivo in the presence of a recombinant fusion protein PA2024 containing a prostate antigen, prostate acid phosphatase and

Clinical Trial Registry. Retrieved 20 March 2021. "Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01) Phase III (COVID-19)". ClinicalTrials.gov. 27 October

ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein". Nature. 364 (6435): 346–9. Bibcode:1993Natur.364..346M. doi:10.1038/364346a0

protease) cleavage site. HRV 3C is a highly purified recombinant 6XHis-fusion protein, that recognizes the same cleavage site as the native enzyme. Both,

antibody-binding sites incorporated on the virion surface as a glycoprotein D fusion protein". Gene Therapy. 15 (24): 1579–92. doi:10.1038/gt.2008.121. PMID 18701918

difference is the KIF5B promoter inducing higher expression of the KIF5B-RET fusion protein compared to other partners, which would result in incomplete inhibition

agreement with results from in vitro DNA repair assays, a p200 CUX1-GFP fusion protein is rapidly recruited to DNA damage generated by laser microirradiation

Engineering". hdl:1721.1/32535. Grünberg R, Arndt K, Müller K (2009-04-18). "Fusion Protein (Freiburg) Biobrick assembly standard". BBF RFC. 25. hdl:1721.1/45140

associates with lipid rafts U49 Virion-associated regulatory protein, fusion protein U50 DNA packaging U51 Early gene G protein-coupled chemokine receptor

progenitor is transformed by a conditional v-Rel estrogen receptor fusion protein v-RelER". Cell. 80 (2): 341–52. doi:10.1016/0092-8674(95)90417-4. PMID 7834754

P (March 2009). "Development, characterization, and evaluation of a fusion protein of a novel glucagon-like peptide-1 (GLP-1) analog and human serum albumin

in the fused protein, the total change in the Tt associated with the fusion protein, ΔTt,fusion: SI= ∑ X A A {\displaystyle \sum _{XAA}^{}} (ASAXAA/ ASAp)(Ttc)

Georges; Mason, David Y. (15 November 1999). "Lymphomas Expressing ALK Fusion Protein(s) Other Than NPM-ALK". Blood. 94 (10): 3509–3515. PMID 10552961. Falini

1998). "The p47 co-factor regulates the ATPase activity of the membrane fusion protein, p97". FEBS Letters. 437 (3): 255–7. doi:10.1016/s0014-5793(98)01232-0

gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1". Cell Reports. 10 (7): 1082–95. doi:10.1016/j.celrep.2015

(1995). "Expression of recombinant human phenylalanine hydroxylase as fusion protein in Escherichia coli circumvents proteolytic degradation by host cell

Dumont J, Peters RT, et al. (November 2018). "Recombinant factor VIII Fc fusion protein drives regulatory macrophage polarization". Blood Advances. 2 (21):

Li C. (2010) Protective effects of a bacterially expressed NIF-KGF fusion protein against bleomycin-induced acute lung injury in mice. Acta Biochim Biophys

QKI and MYB can prompt an increased expression of in-frame MYB-QKI fusion protein than the normal paediatric cortical brain. The research group proved

preferentially induced on the specific genomic region which is recognized by fusion protein. Because condensates of the same composition can interact and fuse with

with QDs-ConA-beta-CDs-AuNPs. Fluorescent protein can be made into a fusion protein with a desired protein, circumventing the labelling steps. Shultz made

were studied by several CEF groups, including the leukemogenic AF4-MLL fusion protein and RIP1-containing cytosolic complexes that are critical for the initiation

Valenta, Rudolf (15 April 2022). "Vaccine based on folded RBD-PreS fusion protein with potential to induce sterilizing immunity to SARS-CoV-2 variants"

localised to the mitochondrial membrane in mouse cells using a GFP fusion protein. Very little is known about the Mg2+ transport characteristics of the

B. H.; Park, R. W.; Kim, I. S. (2008). "T-CAM, a fastatin-FIII 9-10 fusion protein, potently enhances anti-angiogenic and anti-tumor activity αvβ3 and

biotinylating protein (BirA* instead of APEX) was expressed in cells as a fusion protein with several known stress granule-associated proteins. Proteins in close

was demonstrated by combining L1 and neurofascin into an artificial fusion protein, which improves efficiency since factors are not delivered individually

CYP (except CYP505A1, cytochrome P450 foxy), it constitutes a natural fusion protein between the CYP domain and an electron donating cofactor. Thus, BM3