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searching for HIV-1 protease 65 found (93 total)

Darunavir (1,806 words) [view diff] exact match in snippet view article find links to article

was developed to increase interactions with HIV-1 protease and to be more resistant against HIV-1 protease mutations. With a Kd (dissociation constant)

Stercobilin (561 words) [view diff] exact match in snippet view article find links to article

xanthobilirubic acid — has potential to function as a new class of HIV-1 protease inhibitors when delivered at low micromolar concentrations. These pigments

Mozenavir (265 words) [view diff] exact match in snippet view article find links to article

approach to protein--ligand interactions: polarization effects of the HIV-1 protease on selected high affinity inhibitors". Journal of Medicinal Chemistry

Ramakrishna V. Hosur (1,745 words) [view diff] exact match in snippet view article find links to article

sequences. He is reported to have explained the folding hierarchy in HIV-1 protease, the native state energy landscape, and structural and dynamic characteristics

Biliverdin (1,398 words) [view diff] exact match in snippet view article find links to article

– as well as many other tetrapyrrolic pigments – may function as an HIV-1 protease inhibitor as well as having beneficial effects in asthma though further

HIV-associated lipodystrophy (352 words) [view diff] exact match in snippet view article find links to article

[citation needed] On the one hand, lipodystrophy seems to be mainly due to HIV-1 protease inhibitors. Interference with lipid metabolism is postulated as pathophysiology

ACTG2 (1,017 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biol. (Praha). 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

Indinavir (2,373 words) [view diff] exact match in snippet view article find links to article

stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S". Journal of Molecular

Actin, alpha skeletal muscle (1,505 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biologica. 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

SPTBN5 (363 words) [view diff] exact match in snippet view article find links to article

"Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease". Cell Biol. Int. 26 (6): 529–39. doi:10.1006/cbir.2002.0895. PMID 12119179

ACTA2 (1,136 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biologica. 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

Tenofovir disoproxil (2,374 words) [view diff] exact match in snippet view article find links to article

elevated serum concentrations. Tenofovir interacts with didanosine and HIV-1 protease inhibitors. Tenofovir increases didanosine concentrations and can result

ACTC1 (2,007 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biologica. 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

GLRX (892 words) [view diff] exact match in snippet view article find links to article

detected within HIV-1 and can regulate the activity of glutathionylated HIV-1 protease in vitro". J. Biol. Chem. 272 (41): 25935–40. doi:10.1074/jbc.272.41

PHKB (612 words) [view diff] exact match in snippet view article find links to article

(1991). "Cleavage of phosphorylase kinase and calcium-free calmodulin by HIV-1 protease". Biochem. Biophys. Res. Commun. 178 (3): 892–8. doi:10.1016/0006-291X(91)90975-D

EIF4G2 (1,114 words) [view diff] exact match in snippet view article find links to article

PMID 11943866. Perales C, Carrasco L, Ventoso I (2003). "Cleavage of eIF4G by HIV-1 protease: effects on translation". FEBS Lett. 533 (1–3): 89–94. doi:10

SPTBN2 (755 words) [view diff] exact match in snippet view article find links to article

"Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease". Cell Biol. Int. 26 (6): 529–39. doi:10.1006/cbir.2002.0895. PMID 12119179

GLRX5 (870 words) [view diff] exact match in snippet view article find links to article

detected within HIV-1 and can regulate the activity of glutathionylated HIV-1 protease in vitro". The Journal of Biological Chemistry. 272 (41): 25935–40.

Phosphorylase kinase, alpha 1 (614 words) [view diff] exact match in snippet view article find links to article

(1991). "Cleavage of phosphorylase kinase and calcium-free calmodulin by HIV-1 protease". Biochem. Biophys. Res. Commun. 178 (3): 892–8. doi:10.1016/0006-291X(91)90975-D

Actin, cytoplasmic 2 (2,991 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biologica. 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

Arecatannin B1 (84 words) [view diff] no match in snippet view article find links to article

medicine for inhibitory effects on human immunodeficiency virus type 1 (HIV-1) protease. Kusumoto I.T., Nakabayashi T., Kida H., Miyashiro H., Hattori M.,

PHKA2 (938 words) [view diff] exact match in snippet view article find links to article

(1991). "Cleavage of phosphorylase kinase and calcium-free calmodulin by HIV-1 protease". Biochem. Biophys. Res. Commun. 178 (3): 892–8. doi:10.1016/0006-291X(91)90975-D

SPTBN1 (997 words) [view diff] exact match in snippet view article find links to article

"Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease". Cell Biol. Int. 26 (6): 529–39. doi:10.1006/cbir.2002.0895. PMID 12119179

SPTBN4 (751 words) [view diff] exact match in snippet view article find links to article

"Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease". Cell Biol. Int. 26 (6): 529–39. doi:10.1006/cbir.2002.0895. PMID 12119179

Topological drugs (1,446 words) [view diff] exact match in snippet view article find links to article

Sijbesma; G. Srdanov; F. Wudl; G. L. Kenyon (1993). "Inhibition of the HIV-1 protease by fullerene derivatives: model building studies and experimental verification"

Quenching (fluorescence) (1,023 words) [view diff] exact match in snippet view article

WM (2006). "Quenched near-infrared fluorescent peptide substrate for HIV-1 protease assay". In Achilefu S, Bornhop DJ, Raghavachari R (eds.). Optical Molecular

FLNB (1,335 words) [view diff] exact match in snippet view article find links to article

"Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease". Cell Biol. Int. 26 (6): 529–39. doi:10.1006/cbir.2002.0895. PMID 12119179

Alpha-actinin-1 (1,374 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biol. (Praha). 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

Spectrin, alpha 1 (1,041 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biol. (Praha). 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

Areca catechu (1,165 words) [view diff] no match in snippet view article find links to article

medicine for inhibitory effects on human immunodeficiency virus type 1 (HIV-1) protease". Phytotherapy Research. 9 (3): 180–184. doi:10.1002/ptr.2650090305

Atazanavir (1,078 words) [view diff] exact match in snippet view article find links to article

(August 1998). "New aza-dipeptide analogues as potent and orally absorbed HIV-1 protease inhibitors: candidates for clinical development". Journal of Medicinal

PLS3 (817 words) [view diff] exact match in snippet view article find links to article

"Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease". Cell Biol. Int. 26 (6): 529–39. doi:10.1006/cbir.2002.0895. PMID 12119179

Enzyme inhibitor (11,575 words) [view diff] exact match in snippet view article find links to article

S2CID 25269012. Qiu X, Liu ZP (2011). "Recent developments of peptidomimetic HIV-1 protease inhibitors". Current Medicinal Chemistry. 18 (29): 4513–37. doi:10

Beta-actin (997 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biologica. 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

MAP1A (1,000 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1996). "The cleavage of host cell proteins by HIV-1 protease". Folia Biol. (Praha). 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

GLRX2 (1,824 words) [view diff] exact match in snippet view article find links to article

detected within HIV-1 and can regulate the activity of glutathionylated HIV-1 protease in vitro". The Journal of Biological Chemistry. 272 (41): 25935–40.

MAP1LC3A (1,150 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biol. (Praha). 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

Arecatannin (234 words) [view diff] no match in snippet view article find links to article

medicine for inhibitory effects on human immunodeficiency virus type 1 (HIV-1) protease. Ines Tomoco Kusumoto, Takeshi Nakabayashi1, Hiroaki Kida, Hirotsugu

Vimentin (2,529 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biologica. 42 (5): 227–230. doi:10.1007/BF02818986. PMID 8997639

FLNC (gene) (2,371 words) [view diff] exact match in snippet view article

"Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease". Cell Biology International. 26 (6): 529–39. doi:10.1006/cbir.2002

PARP4 (990 words) [view diff] exact match in snippet view article find links to article

2002.9438. PMID 12140175. Nie Z, Phenix BN, Lum JJ, et al. (2003). "HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome

Carbonaceous chondrite (3,244 words) [view diff] case mismatch in snippet view article find links to article

(1992-06-05). "Total Chemical Synthesis of a D-Enzyme: The Enantiomers of HIV-1 Protease Show Reciprocal Chiral Substrate Specificity". Science. 256 (5062):

Stephen Kent (chemist) (693 words) [view diff] exact match in snippet view article

2000;69:923-60. Total chemical synthesis of a D-enzyme: the enantiomers of HIV-1 protease show reciprocal chiral substrate specificity [corrected]. Milton RC

Microtubule-associated protein 2 (1,378 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biol. (Praha). 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

Dark quencher (660 words) [view diff] exact match in snippet view article find links to article

Volcheck, W.M., Quenched near-infrared fluorescent peptide substrate for HIV-1 protease assay, Proc. SPIE, 2006; (6097), [1][permanent dead link] J. Lakowicz

Clostridial Cytotoxin family (1,285 words) [view diff] case mismatch in snippet view article find links to article

Montellano, Paul R. Ortiz de (1996-06-26). "Irreversible Inhibition of the HIV-1 Protease: Targeting Alkylating Agents to the Catalytic Aspartate Groups". Journal

Intermediate filament (3,168 words) [view diff] exact match in snippet view article find links to article

architecture and chromatin distribution, and the liberation of heads by HIV-1 protease may play an important role in HIV-1 associated cytopathogenesis and

NFKB1 (2,363 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biol. (Praha). 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

Rudi Pauwels (3,464 words) [view diff] exact match in snippet view article find links to article

clinical isolates. Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor. Development of drug Discovery method for SARS and now also

Satish K. Gupta (1,687 words) [view diff] exact match in snippet view article find links to article

Lagerstroemia speciosa L. inhibit HIV-1 infection through inhibition of HIV-1 protease & reverse transcriptase activity". Indian J Med Res. 137 (3): 540–548

Lauren V. Wood (1,775 words) [view diff] exact match in snippet view article find links to article

vitro evidence of inhibition of mitochondrial protease processing by HIV-1 protease inhibitors in yeast: a possible contribution to lipodystrophy syndrome"

Multi-label classification (2,945 words) [view diff] exact match in snippet view article find links to article

Senge, R; Neumann, U; Hüllermeier, E; Heider, D (2016). "Exploiting HIV-1 protease and reverse transcriptase cross-resistance information for improved

Schellman loop (1,139 words) [view diff] exact match in snippet view article find links to article

extraction of localized sequence features; specificity results for HIV-1 protease and structure-function results for the Schellman loop". Bioinformatics

Fibronectin (3,766 words) [view diff] exact match in snippet view article find links to article

Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biologica. 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639

Samuel Gan (1,983 words) [view diff] exact match in snippet view article find links to article

(2016). "Structural analyses of 2015-updated drug-resistant mutations in HIV-1 protease: an implication of protease inhibitor cross-resistance". BMC Bioinformatics

Fungus (19,103 words) [view diff] no match in snippet view article find links to article

Hattori M, Kakiuchi N, et al. (November 1998). "Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum". Phytochemistry. 49 (6): 1651–7.

Ramakanth Sarabu (1,164 words) [view diff] case mismatch in snippet view article find links to article

Prodrug Strategy with Bio-activation To Improve Oral Delivery of the HIV-1 Protease Inhibitor Atazanavir". Journal of Medicinal Chemistry. 61 (9): 4176–4188

TLN2 (2,337 words) [view diff] exact match in snippet view article find links to article

"Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease". Cell Biology International. 26 (6): 529–39. doi:10.1006/cbir.2002

Enzyme (9,819 words) [view diff] exact match in snippet view article find links to article

PMID 1464741. Wlodawer A, Vondrasek J (1998). "Inhibitors of HIV-1 protease: a major success of structure-assisted drug design". Annual Review of

Caspase-activated DNase (3,047 words) [view diff] exact match in snippet view article find links to article

Phenix BN, Lum JJ, Alam A, Lynch DH, Beckett B, et al. (November 2002). "HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome

Dhevalapally B. Ramachary (2,144 words) [view diff] case mismatch in snippet view article find links to article

Cascade Three-Component Reductive Alkylations: Formal Total Synthesis of HIV-1 Protease Inhibitors, Antibiotic Agglomerins, Brefeldin A, and (R)-γ-Hexanolide"

David B. Fogel (1,458 words) [view diff] exact match in snippet view article find links to article

Freer, ST (1995). "Molecular recognition of the inhibitor AG-1343 by HIV-1 protease: conformationally flexible docking by evolutionary programming". Chem

Transition state theory (5,817 words) [view diff] exact match in snippet view article find links to article

with the intention of inhibiting the target enzyme. Examples include HIV-1 protease, racemases, β-lactamases, metalloproteinases, cyclooxygenases and many

D-peptide (1,018 words) [view diff] exact match in snippet view article find links to article

(1992). "Total chemical synthesis of a D-enzyme: the enantiomers of HIV-1 protease show demonstration of reciprocal chiral substrate specificity". Science

Peter Coveney (2,772 words) [view diff] case mismatch in snippet view article find links to article

V. (2014). "Computing Clinically Relevant Binding Free Energies of HIV-1 Protease Inhibitors". Journal of Chemical Theory and Computation. 10 (3): 1228–1241