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Longer titles found: Etirinotecan pegol (view)

searching for Irinotecan 47 found (381 total)

alternate case: irinotecan

Abituzumab (974 words) [view diff] exact match in snippet view article find links to article

compare the efficacy of Abituzumab, cetuximab, and irinotecan compared to cetuximab and irinotecan in patients with KRAS (exon 2) wild-type metastatic

Semaxanib (543 words) [view diff] exact match in snippet view article find links to article

2006). "Phase I/pilot study of SU5416 (semaxinib) in combination with irinotecan/bolus 5-FU/LV (IFL) in patients with metastatic colorectal cancer". American

Tigatuzumab (337 words) [view diff] exact match in snippet view article find links to article

2011. Clinical trial number NCT00969033 for "CS-1008 Used With Irinotecan Versus Irinotecan Alone in Subjects With Metastatic Colorectal Carcinoma Who Failed

Integrin alpha V (708 words) [view diff] exact match in snippet view article find links to article

(January 2015). "Abituzumab combined with cetuximab plus irinotecan versus cetuximab plus irinotecan alone for patients with KRAS wild-type metastatic colorectal

Cancer pharmacogenomics (4,060 words) [view diff] exact match in snippet view article find links to article

in exon 1. Irinotecan is a prodrug used in the treatment of many solid tumours, including colorectal, pancreatic, and lung cancer. Irinotecan is metabolized

MM-151 (1,208 words) [view diff] exact match in snippet view article find links to article

MM-151 and determine the dose of MM-151 alone and in combination with irinotecan to be used for a phase 2 trial. There were 3 arms involved in this trial;

Ipsen (2,137 words) [view diff] exact match in snippet view article find links to article

the disease. In February 2024, Ipsen received FDA approval for Onivyde (irinotecan liposome injection), which is used in combination with oxaliplatin, fluorouracil

Enterohepatic circulation (769 words) [view diff] exact match in snippet view article find links to article

for a small number of drugs that are very toxic to the intestine (e.g. irinotecan), these molecules which would not otherwise be very toxic can become so

Gedatolisib (855 words) [view diff] exact match in snippet view article find links to article

trial number NCT01925274 for "A Study Of PF-05212384 Plus Irinotecan Vs Cetuximab Plus Irinotecan In Patients With KRAS And NRAS Wild Type Metastatic Colorectal

Gliosarcoma (1,557 words) [view diff] exact match in snippet view article find links to article

, vincristine, cisplatin, mithramycin, ametophterin, thalidomide, or irinotecan have all been recorded as treatment options for gliosarcoma and radiotherapy

Panitumumab (1,421 words) [view diff] exact match in snippet view article find links to article

disease progression on or following fluoropyrimidine-, oxaliplatin-, and irinotecan-containing regimens, based on the results of a study which showed clinical

Intraperitoneal injection (2,425 words) [view diff] exact match in snippet view article find links to article

chemotherapy. They are mitomycin C, cisplatin, carboplatin, oxaliplatin, irinotecan, 5-fluorouracil, gemcitabine, paclitaxel, docetaxel, doxorubicin, premetrexed

Trastuzumab deruxtecan (2,053 words) [view diff] exact match in snippet view article find links to article

4 mg/kg intravenously every three weeks or physician's choice of either irinotecan or paclitaxel monotherapy. Efficacy was based on DESTINY-Breast03 (NCT03529110)

Charles S. Fuchs (249 words) [view diff] exact match in snippet view article find links to article

2004). "A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic

Kadmon Corporation (1,685 words) [view diff] exact match in snippet view article find links to article

anticancer agents. In 2014 KD018 was in a Phase II trial in combination with irinotecan in metastatic colon cancer. In 2011 the company acquired rights from Brighton

Tucatinib (1,683 words) [view diff] exact match in snippet view article find links to article

cancer that has progressed following fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy. Two early stage clinical trials have reported encouraging

Onyx Pharmaceuticals (1,081 words) [view diff] exact match in snippet view article find links to article

have been previously treated with fluoropyrimidine-, oxaliplatin, and irinotecan-based chemotherapy, an anti-VEGF therapy, and, if KRAS wild-type, an anti-EGFR

FOLFOX (1,337 words) [view diff] exact match in snippet view article find links to article

(2004). "A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic

Pegdinetanib (348 words) [view diff] exact match in snippet view article find links to article

Patients With Recurrent Glioblastoma Multiforme and Combination Therapy With Irinotecan" at ClinicalTrials.gov Bloom L, Calabro V (October 2009). "FN3: a new

ImClone Systems (2,186 words) [view diff] exact match in snippet view article find links to article

months. When used in conjunction with a standard chemotherapy treatment, irinotecan, 22.9% of patients responded and tumor growth was delayed by approximately

Carboxylesterase 3 (568 words) [view diff] exact match in snippet view article find links to article

Fredenburg TB, Davis WI, Murry DJ, Bosron WF (Apr 2004). "Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino]

Monobody (1,490 words) [view diff] exact match in snippet view article find links to article

Patients With Recurrent Glioblastoma Multiforme and Combination Therapy With Irinotecan" at ClinicalTrials.gov Bloom L, Calabro V (July 2009). "FN3: a new protein

BI 1701963 (210 words) [view diff] exact match in snippet view article find links to article

combination with MEK inhibitors, irreversible KRASG12C inhibitors or irinotecan". Cancer Research. 81 (13_Supplement): CT210–CT210. doi:10.1158/1538-7445

Optimer ligand (1,551 words) [view diff] exact match in snippet view article find links to article

validation of a selective SPR aptasensor for the detection of anticancer drug irinotecan in human plasma samples". Analytical and Bioanalytical Chemistry. 413

Yamazaki-Teiichi Prize (1,304 words) [view diff] exact match in snippet view article find links to article

self-organization. 2013 - Tadashi Miyasaka [ja], Seigo Sawada, Teruo Yokokura [ja]. Irinotecan hydrochloride: the first established anticancer agent as camptothecin

Urachal cancer (1,647 words) [view diff] exact match in snippet view article find links to article

(2015-03-01). "A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab". Urology Case Reports

Navitoclax (1,219 words) [view diff] exact match in snippet view article find links to article

combination with chemotherapies (paclitaxel, docetaxel, gemcitabine, and irinotecan), olaparib, erlotinib, venetoclax, and rituximab in advanced hematological

ImClone stock trading case (2,798 words) [view diff] exact match in snippet view article find links to article

growth by 1.5 months. When used in conjunction with a standard treatment irinotecan, 22.9% of patients responded and tumor growth was delayed by approximately

Metastasectomy (1,597 words) [view diff] exact match in snippet view article find links to article

Survival update and prognostic factor analysis of oxaliplatin (Ox) and irinotecan (Iri) combinations for metastatic colorectal cancer (MCRC)". J. Clin.

Tina Young Poussaint (778 words) [view diff] exact match in snippet view article find links to article

M.; Kun, Larry E. (2010-06-20). "Lack of Efficacy of Bevacizumab Plus Irinotecan in Children With Recurrent Malignant Glioma and Diffuse Brainstem Glioma:

Tiomolibdic acid (1,597 words) [view diff] exact match in snippet view article find links to article

anti-angiogenic copper lowering agent tetrathiomolybdate in combination with irinotecan, 5-flurouracil, and leucovorin for metastatic colorectal cancer". Investigational

Schedule H (253 words) [view diff] case mismatch in snippet view article find links to article

IOHEXOL 255. IOPAMIDOL 4 256. IOMEPROL 257. IOPROMIDE 258. IRBESARTAN 259. IRINOTECAN HYDROCHLORIDE 260. IRON PREPARATION FOR PARENTERAL USE 261. ISEPAMICINE

Dafna Bar-Sagi (874 words) [view diff] exact match in snippet view article find links to article

E; Bar-Sagi, D; Godin, R; Leichman, L P. A Phase lb Studying Combining Irinotecan With AZD1775, A Selective WEE 1 Kinase Inhibitor, in RAS/RAF Mutated Metastatic

Topoisomerase (6,173 words) [view diff] exact match in snippet view article find links to article

acuminata, targets human topo I and derivatives such as topotecan and irinotecan are widely used in cancer chemotherapy. Camptothecin and its derivatives

Pharmacogenomics (6,773 words) [view diff] exact match in snippet view article find links to article

considered as critical issues for patients treated with 5-FU/capecitabine, irinotecan, mercaptopurine/azathioprine, gemcitabine/capecitabine/AraC and tamoxifen

Wilson Therapeutics (1,037 words) [view diff] exact match in snippet view article find links to article

anti-angiogenic copper lowering agent tetrathiomolybdate in combination with irinotecan, 5-flurouracil, and leucovorin for metastatic colorectal cancer". Invest

Interventional radiology (13,206 words) [view diff] exact match in snippet view article find links to article

themselves loaded with the chemotherapy agent—typically doxorubicin or irinotecan. Selective internal radiation therapy (also known as SIRT or Y-90 radioembolization):

Let-7 microRNA precursor (8,297 words) [view diff] exact match in snippet view article find links to article

metastatic colorectal cancer patients treated with salvage cetuximab-irinotecan". The Pharmacogenomics Journal. 10 (5): 458–464. doi:10.1038/tpj.2010

Glypican 3 (2,625 words) [view diff] exact match in snippet view article find links to article

of Hepatocellular Carcinoma by GPC3-Targeted Bispecific Antibody and Irinotecan is Potent in Suppressing Tumor Growth in Mice". Molecular Cancer Therapeutics

Burghardt Wittig (2,139 words) [view diff] exact match in snippet view article find links to article

carcinoembryonic antigen-derived HLA-A2-restricted CAP-1 peptide and irinotecan, 5-fluorouracil, and leucovorin in patients with primary metastatic colorectal

Plus Therapeutics (2,003 words) [view diff] exact match in snippet view article find links to article

chemotherapeutic agents directly to brain tumor, including drugs such as irinotecan and topotecan. If NanoLiposomes are to be utilized as a carrier for radioisotopes

ABC transporter (14,391 words) [view diff] exact match in snippet view article find links to article

resistance to most Topoisomerase I or II inhibitors such as topotecan, irinotecan, and doxorubicin. It is unclear exactly how these proteins can translocate

Copper in biology (12,350 words) [view diff] exact match in snippet view article find links to article

anti-angiogenic copper lowering agent tetrathiomolybdate in combination with irinotecan, 5-flurouracil, and leucovorin for metastatic colorectal cancer". Investigational

Epigenetic priming (2,249 words) [view diff] exact match in snippet view article find links to article

Ushijima, T. (2020). Epigenetic priming sensitizes gastric cancer cells to irinotecan and cisplatin by restoring multiple pathways. Gastric cancer, 23(1), 105-115

C8orf34 (2,326 words) [view diff] exact match in snippet view article find links to article

Kim JY, Lee JS (October 2013). "A genome-wide association study for irinotecan-related severe toxicities in patients with advanced non-small-cell lung

Jim Bishop (doctor) (2,779 words) [view diff] exact match in snippet view article

, Clarke, S., Bishop, J., Dodds, H. and Rivory, L 2001, 'Toxicity of irinotecan (CPT-11) and hepato-renal dysfunction,' Anti-Cancer Drugs: international

Irreversible electroporation (7,907 words) [view diff] exact match in snippet view article find links to article

treatment with FOLFIRINOX (a combination of 5-fluorouracil, leucovorin, irinotecan, and oxaliplatin) (median OS, 12–14months). However, IRE appears to be