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Longer titles found: International Knockout Mouse Consortium (view)

searching for Knockout mouse 114 found (204 total)

MiR-218 microRNA precursor family (477 words) [view diff] exact match in snippet view article find links to article

neuromuscular junction failure, and neurodegeneration, as demonstrated by knockout mouse models. The involvement of miR-218 in cancer has also been investigated

CD83 (2,266 words) [view diff] exact match in snippet view article find links to article

phenotype. Foxp3 expression is not affected by loss of CD83 in a CD83 knockout mouse. In contrast, CD83 seems important for peripheral Treg cell induction

Conditional gene knockout (1,292 words) [view diff] exact match in snippet view article find links to article

Magnuson, T., Moore, M. W., Nagy, A., ... Zambrowicz, B. (2004). The knockout mouse project. Nature genetics, 36(9), 921–924. https://doi.org/10.1038/ng0904-921

RUNX3 (1,992 words) [view diff] no match in snippet view article find links to article

Runt-related transcription factor 3 is a protein that in humans is encoded by the RUNX3 gene. This gene encodes a member of the runt domain-containing

Estrogen-related receptor (1,175 words) [view diff] exact match in snippet view article find links to article

elucidated through the generation of sophisticated tissue-specific gene knockout mouse models.[citation needed] Schreiber SN, Emter R, Hock MB, Knutti D, Cardenas

AHI1 (1,237 words) [view diff] exact match in snippet view article find links to article

due to the role it plays in brain development. An AHI1 heterozygous knockout mouse model was studied by Bernard Lerer and his group at Hadassah Medical

CYP26B1 (1,262 words) [view diff] exact match in snippet view article find links to article

forming limb bud with an abundance in the apical ectodermal ridge. In a knockout mouse model, mice manifest with severe limb malformations and die after birth

TBX2 (2,749 words) [view diff] exact match in snippet view article find links to article

defects of the outflow tract, and this has been shown using a knockout mouse. The knockout mouse is a mouse in which the gene is inactivated in order to study

Genetic ablation (1,066 words) [view diff] exact match in snippet view article find links to article

example of this method in action can be seen through the production of a knockout mouse. This is accomplished through the administration of one or more transgenes

TNFAIP3 (1,971 words) [view diff] exact match in snippet view article find links to article

jellyfish, anemones) with a conserved protein domain composition. Using knockout mouse models of TNFAIP3 and its transcriptional repressor (i.e. KCHIP3), TNFAIP3

Benzopyrene (614 words) [view diff] exact match in snippet view article find links to article

HG; Gonzalez, FJ; Nebert, DW (2006). "Oral Benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required

Alexander Fleming Biomedical Sciences Research Center (438 words) [view diff] exact match in snippet view article find links to article

inbred strains or genetically engineered mice, such as transgenic and knockout mouse lines, as well as chemically induced mutants developed by Fleming researchers

THOC5 (1,483 words) [view diff] exact match in snippet view article find links to article

suggesting that THOC5 may be involved in cancer development. Recent THOC5 knockout mouse data reveal that THOC5 is an essential element in the maintenance of

POMT1 (1,019 words) [view diff] exact match in snippet view article find links to article

"Impairment of photoreceptor ribbon synapses in a novel Pomt1 conditional knockout mouse model of dystroglycanopathy". Scientific Reports. 8 (1): 8543. Bibcode:2018NatSR

Lexicon Pharmaceuticals (1,070 words) [view diff] exact match in snippet view article find links to article

large majority of human genes having a counterpart in the mouse genome, knockout mouse technology has become a powerful tool in the discovery of new medicines

Jackson Laboratory (2,001 words) [view diff] case mismatch in snippet view article find links to article

modeling. The National Institutes of Health (NIH) funds phase 2 of the Knockout Mouse Production and Phenotyping Project (KOMP2). Researchers link mutations

JAG1 (2,693 words) [view diff] exact match in snippet view article find links to article

models where the Jag1 gene is turned off in certain tissues (conditional knockout mouse models) have been used to study the role of Jag1 in many tissue specific

HSD17B4 (1,374 words) [view diff] exact match in snippet view article find links to article

"Peroxisomal multifunctional protein-2: the enzyme, the patients and the knockout mouse model". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology

Metadoxine (1,907 words) [view diff] exact match in snippet view article find links to article

occur in 59-80% of individuals with FXS. In a FXS animal model (Fmr1 knockout mouse model), metadoxine treatment improved behavioral impairments of learning

Site-specific recombinase technology (3,200 words) [view diff] no match in snippet view article find links to article

functional annotation of the mouse genome (coordinated by the International Knockout-Mouse Consortium, IKMC) with the ultimate goal to have all protein genes mutated

Retinol binding protein 4 (2,035 words) [view diff] exact match in snippet view article find links to article

Stargardt's disease and macular degeneration. An animal study using ABCA4 knockout mouse proved that reduction in serum RBP4 level could inhibit lipofuscin without

Lacritin (4,892 words) [view diff] exact match in snippet view article find links to article

lacritin promotes tearing in rabbit preclinical studies. In the Aire knockout mouse model of dry eye (considered similar to human Sjogren's syndrome), topical

C57BL/6 (1,001 words) [view diff] exact match in snippet view article find links to article

therefore it is used even more. In 1993 the first C57BL/6 gene targeted knockout mouse was published by a group at Hoffmann-La Roche in Switzerland. In 2013

Syncoilin (1,529 words) [view diff] exact match in snippet view article find links to article

"Analysis of skeletal muscle function in the C57BL6/SV129 syncoilin knockout mouse". Mammalian Genome. 19 (5): 339–351. doi:10.1007/s00335-008-9120-2.

Proprotein convertase (1,249 words) [view diff] case mismatch in snippet view article find links to article

Potential of Furin Inhibition: An Evaluation Using a Conditional Furin Knockout Mouse Model, by Jeroen Declercq and Prof. Dr. J.W.M. Creemers, Morgan & Claypool

KLF1 (1,159 words) [view diff] no match in snippet view article find links to article

critical function of KLF1 in hematopoietic development. KLF1 deficient (knockout) mouse embryos exhibit a lethal anemic phenotype, fail to promote the transcription

EN1 (gene) (1,168 words) [view diff] exact match in snippet view article

tissues such as somites and limb ectoderm throughout development. A knockout mouse model with the En1 homeobox deleted was developed; mice died less than

Lipofuscin (1,697 words) [view diff] exact match in snippet view article find links to article

this holds in vivo over longer time periods is not clear. The ABCR -/- knockout mouse has delayed dark adaptation but normal final rod threshold relative

Dent's disease (1,239 words) [view diff] exact match in snippet view article find links to article

citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease". Kidney Int. 68 (2): 642–52. doi:10.1111/j

Genome project (1,822 words) [view diff] case mismatch in snippet view article find links to article

Pathogen Genome Project International Mouse Phenotyping Consortium IMPC Knockout Mouse Phenotyping Project KOMP2 Giant Sequoia, Sequoiadendron giganteum Joint

CYP2R1 (1,133 words) [view diff] exact match in snippet view article find links to article

with knockout of Cyp2r1 and both Cyp2r1 and Cyp27a1. A conditional knockout mouse line called Cyp2r1tm1b(EUCOMM)Wtsi has been generated and animals have

Consortium for Functional Glycomics (1,778 words) [view diff] exact match in snippet view article find links to article

closed. From 2001 to 2009, Core F generated 26 total and conditional knockout mouse lines deficient in glycan-binding proteins or glycosyltransferases.

Estrogen receptor (3,818 words) [view diff] exact match in snippet view article find links to article

receptor-beta (ERbeta) messenger ribonucleic acid in the wild-type and ERalpha-knockout mouse". Endocrinology. 138 (11): 4613–21. doi:10.1210/en.138.11.4613. PMID 9348186

Kodi Ravichandran (835 words) [view diff] exact match in snippet view article find links to article

biological, biochemical, and in vivo analyses using transgenic and knockout mouse models, and models of human inflammatory diseases including arthritis

Prolactin receptor (1,865 words) [view diff] exact match in snippet view article find links to article

prolactin-regulated gene in reproductive tissues using the prolactin receptor knockout mouse model". primary. Biology of Reproduction. 66 (4): 1210–8. doi:10.1095/biolreprod66

Small Maf (3,041 words) [view diff] exact match in snippet view article find links to article

The p45 NF-E2-sMaf heterodimers are critical for platelet production. Knockout mouse studies have shown that MafG knockout mice show mild thrombocytopenia

Interleukin 25 (2,281 words) [view diff] exact match in snippet view article find links to article

cytokines IL-4, IL-5 and IL-13 have been demonstrated in the IL-25 knockout mouse. IL-25 influences the development of nasal polyps, and may also be involved

Glutamate–cysteine ligase (2,291 words) [view diff] exact match in snippet view article find links to article

characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response"

Vasopressin receptor 1B (1,757 words) [view diff] exact match in snippet view article find links to article

Various stress-induced elevations of ACTH are blunted in the Avpr1b knockout mouse. AVPR1B is expressed at high levels in ACTH-secreting pituitary adenomas

MDFI (744 words) [view diff] exact match in snippet view article find links to article

by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also

CTRL (gene) (444 words) [view diff] exact match in snippet view article

et al. (2002). "Mast cell chymase degrades apoE and apoA-II in apoA-I-knockout mouse plasma and reduces its ability to promote cellular cholesterol efflux"

ABCA1 (2,082 words) [view diff] exact match in snippet view article find links to article

diseases such as atherosclerosis, cancer, and macular degeneration" Knockout mouse models of AMD treated with agonists that increase ABCA1 in loss of function

Thymine-DNA glycosylase (1,605 words) [view diff] exact match in snippet view article find links to article

remove uracil and 5-bromouracil from mispairings with guanine. TDG knockout mouse models showed no increase in mispairing frequency suggesting that other

FANCI (1,363 words) [view diff] exact match in snippet view article find links to article

M, Parmar K, Chagraoui J, Vignard J, et al. (August 2019). "A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2". Nucleic

Toll-like receptor 2 (2,409 words) [view diff] exact match in snippet view article find links to article

Derkenne S, Miller ML, et al. (April 2006). "Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required

Phosphatidylinositol 3,5-bisphosphate (2,639 words) [view diff] exact match in snippet view article find links to article

development as evidenced by the preimplantation lethality of the PIKfyve knockout mouse model. The fact that the heterozygous PIKfyve mice are ostensibly normal

CJC-1295 (843 words) [view diff] exact match in snippet view article find links to article

hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse". American Journal of Physiology. Endocrinology and Metabolism. 291

Schneckenbecken dysplasia (741 words) [view diff] exact match in snippet view article find links to article

"Schneckenbecken dysplasia". In 2007, Hiraoka et al. created an SLC35D1-knockout mouse model, said experiment revealed that while mice heterozygous for the

Pseudocholinesterase deficiency (1,530 words) [view diff] case mismatch in snippet view article find links to article

G.; Carlson, M.; Lockridge, O. (2007). "The Butyrylcholinesterase Knockout Mouse as a Model for Human Butyrylcholinesterase Deficiency". Journal of Pharmacology

GRXCR1 (487 words) [view diff] case mismatch in snippet view article find links to article

Mouse Resources Portal, Wellcome Trust Sanger Institute. "International Knockout Mouse Consortium". van der Weyden L, White JK, Adams DJ, Logan DW (2011).

Myelin (4,083 words) [view diff] exact match in snippet view article find links to article

K, Surendran S, Tyring SK (2006). "Canavan disease: studies on the knockout mouse". N-Acetylaspartate. Advances in Experimental Medicine and Biology.

ACADL (1,610 words) [view diff] exact match in snippet view article find links to article

unmet anaplerotic needs in the fasted long-chain acyl-CoA dehydrogenase knockout mouse". Cardiovascular Research. 100 (3): 441–9. doi:10.1093/cvr/cvt212. PMID 24042017

Myoglobin (3,082 words) [view diff] exact match in snippet view article find links to article

Laussmann T, Flögel U, et al. (Apr 2004). "Adaptation of the myoglobin knockout mouse to hypoxic stress". American Journal of Physiology. Regulatory, Integrative

Estrogen receptor test (1,311 words) [view diff] exact match in snippet view article find links to article

of estrogen receptors, ERα and ERβ, identified by estrogen receptor knockout mouse". Laboratory Animal Research. 28 (2): 71–6. doi:10.5625/lar.2012.28

Monica Justice (481 words) [view diff] case mismatch in snippet view article find links to article

29, 2011). "NIH awards $34 million to Baylor College of Medicine for Knockout Mouse Project". Baylor College of Medicine. Retrieved February 12, 2022. Picton

Mammary gland (5,473 words) [view diff] exact match in snippet view article find links to article

Broadus, A. E. (1998). "Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for

Jay Tischfield (775 words) [view diff] exact match in snippet view article find links to article

characterized by severe kidney stones. The laboratory has developed knockout mouse models for both kidney stone diseases and is developing therapies. Another

ABCA4 (2,750 words) [view diff] exact match in snippet view article find links to article

ready to transfer another molecule of NR-PE/ATR again. The ABCR -/- knockout mouse has delayed dark adaptation but normal final rod threshold relative

Oxidative stress (6,124 words) [view diff] exact match in snippet view article find links to article

"Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency".

Free-radical theory of aging (3,070 words) [view diff] exact match in snippet view article find links to article

(2009). "The mitochondrial theory of aging: Insight from transgenic and knockout mouse models". Experimental Gerontology. 44 (4): 256–60. doi:10.1016/j.exger

Atrial natriuretic peptide (3,832 words) [view diff] exact match in snippet view article find links to article

in exaggerated cardiac hypertrophy in the atrial natriuretic peptide knockout mouse". Cardiovascular Research. 61 (4): 771–779. doi:10.1016/j.cardiores

Sex-determining region Y protein (4,896 words) [view diff] exact match in snippet view article find links to article

Asahara, Hiroshi; Takada, Shuji (5 November 2013). "Production of Sry knockout mouse using TALEN via oocyte injection". Scientific Reports. 3 (1): 3136.

Axon (6,915 words) [view diff] case mismatch in snippet view article find links to article

K, Surendran S, Tyring SK (2006). "Canavan Disease: Studies on the Knockout Mouse". N-Acetylaspartate. Advances in Experimental Medicine and Biology.

Telethonin (3,491 words) [view diff] exact match in snippet view article find links to article

functional evidence for this has come from studies utilizing a Telethonin-knockout mouse (KO), which have shown that Telethonin is involved in T-tubule structure

Mothers against decapentaplegic homolog 3 (4,177 words) [view diff] exact match in snippet view article find links to article

SMAD3-knockout mice are resistant to high-fat-diet induced obesity. SMAD3-knockout mouse is a legitimate animal model of human aneurysms‐osteoarthritis syndrome

Fragile X syndrome (6,790 words) [view diff] exact match in snippet view article find links to article

(2002). "Behavioral and neuroanatomical characterization of the Fmr1 knockout mouse". Hippocampus. 12 (1): 39–46. doi:10.1002/hipo.10005. ISSN 1050-9631

Buprenorphine (7,311 words) [view diff] exact match in snippet view article find links to article

activation by beta-endorphin in pons/medulla of the mu-opioid receptor knockout mouse". Neuroscience. 115 (3): 715–721. doi:10.1016/s0306-4522(02)00486-4

Gene (12,720 words) [view diff] exact match in snippet view article find links to article

Bradley A, Bucan M, Capecchi M, Collins FS, et al. (September 2004). "The knockout mouse project". Nature Genetics. 36 (9): 921–4. doi:10.1038/ng0904-921. PMC 2716027

Amira (software) (3,659 words) [view diff] case mismatch in snippet view article

(2010). "Characterization Of The Airways And Lungs For The FABP/CFTR-Knockout Mouse Using Micro-Computed Tomography And Large Image Microscope Array" (PDF)

(+)-Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide (1,494 words) [view diff] case mismatch in snippet view article

Gonzalez, F. J.; Nebert, D. W. (2006). "Oral Benzo[a]pyrene in Cyp1 Knockout Mouse Lines: CYP1A1 Important in Detoxication, CYP1B1 Metabolism Required

Nancy Carrasco (1,136 words) [view diff] exact match in snippet view article find links to article

dangerous to human health than previously thought. The Carrasco group's NIS knockout mouse has made it possible to generate an animal model of hypothyroidism without

María Blasco Marhuenda (1,303 words) [view diff] exact match in snippet view article find links to article

the core components of mouse telomerase and generation of the first knockout mouse for telomerase; Generation of the first mouse with increased telomerase

Fetuin (1,089 words) [view diff] exact match in snippet view article find links to article

X-ray picture of a Fetuin-A knockout mouse (-/-) compared to a wildtype mouse (+/+). The bright dots in the fetuin-A deficient mouse indicate calcified

Dry eye syndrome (6,282 words) [view diff] exact match in snippet view article find links to article

preclinical studies. Also, topical treatment of eyes of dry eye mice (Aire knockout mouse model of dry eye) restored tearing, and suppressed both corneal staining

Methods used to study memory (5,445 words) [view diff] exact match in snippet view article find links to article

Knockout mouse breeding scheme.

Estrogen receptor beta (4,522 words) [view diff] exact match in snippet view article find links to article

receptor-beta (ERbeta) messenger ribonucleic acid in the wild-type and ERalpha-knockout mouse". Endocrinology. 138 (11): 4613–4621. doi:10.1210/endo.138.11.5496.

Toll-like receptor (6,685 words) [view diff] exact match in snippet view article find links to article

mice, on the other hand, are efficiently infected. As a result, this knockout mouse can act as a disease model of human typhoid fever. Toll-like receptors

NPM1 (4,897 words) [view diff] exact match in snippet view article find links to article

ribosome biogenesis could control the proliferative rate of cells. NPM1 knockout mouse embryos survive upto mid-gestation (9.5dpc-12.5dpc) (Colombo et al.

Perlecan (11,011 words) [view diff] exact match in snippet view article find links to article

that survive die soon after birth. A separately developed perlecan knockout mouse model was created by insertion of a neomycin cassette into exon 7 of

Ignacio Provencio (1,662 words) [view diff] exact match in snippet view article find links to article

Provencio, I.; Menaker, M. (2006). "Nonvisual light responses in the Rpe65 knockout mouse: Rod loss restores sensitivity to the melanopsin system". Proceedings

Inhibitor of DNA-binding protein (1,201 words) [view diff] exact match in snippet view article find links to article

neurons halts neuron axon growth and allows elongation of neurons. Knockout mouse data show that ID genes are essential for heart development. There is

Sonic hedgehog protein (7,133 words) [view diff] exact match in snippet view article find links to article

connection of the esophagus and trachea). Additionally, a double (SHH-/- ) knockout mouse model exhibited poor lung development. The lungs of the SHH double knockout

BBSome (6,786 words) [view diff] exact match in snippet view article find links to article

K., and Sheffield, V.C. (Aug 2011). Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes

WNT4 (3,076 words) [view diff] exact match in snippet view article find links to article

duct as well as a decrease in oocyte numbers. Studies utilizing the knockout mouse model have highlighted the importance of Wnt4 in female reproductive

Leukotriene B4 receptor 2 (6,788 words) [view diff] exact match in snippet view article find links to article

is robustly expressed only in mouse small intestine and skin. LTB4R2 knockout mouse studies, therefore, may reveal a more limited role for the BLT2 receptor

Mutagenesis (molecular biology technique) (2,884 words) [view diff] case mismatch in snippet view article

ISBN 9780123848802. PMID 20699138. "Homologous Recombination Method (and Knockout Mouse)". Davidson College. Damien Biot-Pelletier; Vincent J. J. Martin (2016)

Franziska Grieder (653 words) [view diff] case mismatch in snippet view article find links to article

J.; Soriano, P.; Stewart, D. J.; Stewart, F.; et al. (2004). "The Knockout Mouse Project". Nature Genetics. 36 (9): 921–924. doi:10.1038/ng0904-921.

Epigenetics in stem-cell differentiation (3,692 words) [view diff] exact match in snippet view article find links to article

unchanged by the loss of HDAC2. In order to analyze the process of HDAC knockout mouse in detail, the knockout mice embryonic stem cells were used to generate

Nociception assay (1,991 words) [view diff] no match in snippet view article find links to article

Wilson, Sonya G.; Mogil, Jeffrey S. (2001). "Measuring pain in the (knockout) mouse: Big challenges in a small mammal". Behavioural Brain Research. 125

MicroRNA (16,586 words) [view diff] exact match in snippet view article find links to article

aneurysms. High throughput whole transcriptome profiling of the FoxD1-Dicer knockout mouse model revealed ectopic upregulation of pro-apoptotic gene, Bcl2L11 (Bim)

NKX 2-9 (231 words) [view diff] exact match in snippet view article find links to article

progenitor cell fate. The trigeminal nerve is not affected in the double knockout mouse embryos, indicating that cell fate alteration is limited to the caudal

SIGLEC8 (4,511 words) [view diff] exact match in snippet view article find links to article

ovalbumin (OVA) model of allergic airway inflammation, the Siglec-F knockout mouse exhibits increased lung eosinophilia, enhanced inflammation, delayed

SCARB2 (2,546 words) [view diff] exact match in snippet view article find links to article

proved true in human heart failure. Further analysis employing a LIMP-2 knockout mouse demonstrated that animals lacking LIMP-2 failed to flight a normal hypertrophic

Calponin 3, acidic (1,302 words) [view diff] case mismatch in snippet view article find links to article

Flemming A, Huang QQ, Jin JP, Jumaa H, Herzog S (2015). "A Conditional Knockout Mouse Model Reveals That Calponin-3 Is Dispensable for Early B Cell Development"

Melvin I. Simon (1,628 words) [view diff] case mismatch in snippet view article find links to article

(November 1999). "Increased Susceptibility to Light Damage in an Arrestin Knockout Mouse Model of Oguchi Disease (Stationary Night Blindness)". Investigative

Integrin beta 6 (4,041 words) [view diff] exact match in snippet view article find links to article

results in a significantly reduced expression of ITGB6. The first ITGB6-knockout mouse model was developed in 1996. The mice grew normally, with no difference

Catenin beta-1 (12,345 words) [view diff] exact match in snippet view article find links to article

β-catenin is beneficial or detrimental. A recent study using a conditional knockout mouse that either lacked β-catenin altogether or expressed a non-degradable

Calponin 2 (2,182 words) [view diff] case mismatch in snippet view article find links to article

Flemming A, Huang QQ, Jin JP, Jumaa H, Herzog S (2015). "A Conditional Knockout Mouse Model Reveals That Calponin-3 Is Dispensable for Early B Cell Development"

John Kopchick (1,906 words) [view diff] exact match in snippet view article find links to article

world's longest lived laboratory mouse, the growth hormone receptor knockout mouse. Dr. Kopchick has an h-index of 80, has advised more than 35 Ph.D.,

SNED1 (2,400 words) [view diff] exact match in snippet view article find links to article

promoter of breast cancer metastasis. The recent generation of a Sned1 knockout mouse model is also shedding light on the multiple roles of SNED1 in development

DNA annotation (7,339 words) [view diff] case mismatch in snippet view article find links to article

Blessed annotator: A variation of the museum model, applied in the Knockout Mouse Project (KOMP), in which curators go through a training period prior

Warren Jackson Pledger (1,467 words) [view diff] exact match in snippet view article find links to article

cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse models. Oncogene. 2002 Dec 5;21(55):8486-97. PMID 12466968. Pledger

Wafik El-Deiry (3,588 words) [view diff] exact match in snippet view article find links to article

and to use molecular imaging for drug screening. His group created a knockout mouse of death receptor 5 (DR5) that shows reduced apoptosis in vivo after

TANGO1/MIA3 (1,714 words) [view diff] exact match in snippet view article find links to article

(May 2011). "Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse". The Journal of Cell Biology. 193 (5): 935–51. doi:10.1083/jcb.201007162

SKP2 (4,001 words) [view diff] exact match in snippet view article find links to article

in a p19Arf/p53-independent, but p27-dependent manner. Using a Skp2 knockout mouse model, multiple groups have shown Skp2 is required for cancer development

Retinal waves (2,743 words) [view diff] exact match in snippet view article find links to article

immunotoxins that eliminate certain classes of amacrine cells, or use of knockout mouse lines that have altered spontaneous firing patterns. There are several

RAD9A (3,997 words) [view diff] exact match in snippet view article find links to article

checkpoint, leading to cell cycle arrest in eukaryotes. In conditional knockout mouse models, the loss of Rad9a in the testis results in persistence of DNA

PLAC1 (3,873 words) [view diff] exact match in snippet view article find links to article

important contribution to this idea is the observation that a Plac1 knockout mouse model exhibited both placentomegaly in the dams and growth restriction

Robert K. Naviaux (1,388 words) [view diff] no match in snippet view article find links to article

"Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model". Molecular Autism. 6 (1): 1. doi:10.1186/2040-2392-6-1. ISSN 2040-2392

SBK3 (2,118 words) [view diff] exact match in snippet view article find links to article

have the highest level of SBK3 expression. A novel conditional nebulin knockout mouse model revealed an increase in SBK3 expression in the quadriceps and

SGK1 (4,213 words) [view diff] exact match in snippet view article find links to article

Lang F, Kuhl D (Nov 2002). "Impaired renal Na(+) retention in the sgk1-knockout mouse". The Journal of Clinical Investigation. 110 (9): 1263–1268. doi:10

Developmental bioelectricity (17,264 words) [view diff] exact match in snippet view article find links to article

Francis, H. W (2005). "Inner ear abnormalities in a Kcnq1 (Kvlqt1) knockout mouse: A model of Jervell and Lange-Nielsen syndrome". Otology & Neurotology

CUX1 (4,649 words) [view diff] exact match in snippet view article find links to article

cell lines. Mouse embryo fibroblasts (MEFs) derived from a Cux1-/- knockout mouse exhibit increased genomic instability23, moreover Cux1+/−- heterozygous

James A. Shayman (2,360 words) [view diff] exact match in snippet view article find links to article

three inducible models of vascular disease in the alpha-galactosidase A knockout mouse. These models included oxidant-induced arterial thrombosis, accelerated