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searching for Plasminogen (medication) 72 found (73 total)

alternate case: plasminogen (medication)

Streptokinase (1,615 words) [view diff] no match in snippet view article find links to article

Streptokinase is a thrombolytic medication activating plasminogen by nonenzymatic mechanism. As a medication it is used to break down clots in some cases

Antifibrinolytic (184 words) [view diff] no match in snippet view article find links to article

formation of the fibrinolytic enzyme plasmin from its precursor plasminogen by plasminogen activators (primarily t-PA and u-PA) which takes place mainly

Alteplase (2,334 words) [view diff] no match in snippet view article find links to article

is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic medication used to treat acute ischemic stroke, acute ST-elevation

Tenecteplase (912 words) [view diff] no match in snippet view article find links to article

is an enzyme used as a thrombolytic drug. Tenecteplase is a tissue plasminogen activator (tPA) produced by recombinant DNA technology using an established

Tranexamic acid (3,987 words) [view diff] no match in snippet view article find links to article

binding four to five lysine receptor sites on plasminogen. This decreases the conversion of plasminogen to plasmin, preventing fibrin degradation and

Thrombolysis (1,870 words) [view diff] no match in snippet view article find links to article

secondary fibrinolysis by plasmin through infusion of analogs of tissue plasminogen activator (tPA), the protein that normally activates plasmin. Stroke:

Anakinra (2,070 words) [view diff] no match in snippet view article find links to article

Anakinra, sold under the brand name Kineret, is a biopharmaceutical medication used to treat rheumatoid arthritis, cryopyrin-associated periodic syndromes

Tissue-type plasminogen activator (3,187 words) [view diff] no match in snippet view article find links to article

Tissue-type plasminogen activator, short name tPA, is a protein that facilitates the breakdown of blood clots. It acts as an enzyme to convert plasminogen into

Desmoteplase (1,346 words) [view diff] no match in snippet view article find links to article

salivary plasminogen activator). Desmoteplase, a chemical found in the saliva of vampire bats, has the effect of catalysing the conversion of plasminogen to

Quebec platelet disorder (484 words) [view diff] no match in snippet view article find links to article

characterized by large amounts of the fibrinolytic enzyme urokinase-type plasminogen activator (uPA) in platelets. This causes accelerated fibrinolysis (blood

Thrombus (2,280 words) [view diff] no match in snippet view article find links to article

systemic fibrinolytic state and can lead to bleeding problems. Tissue plasminogen activator (tPA) is a different enzyme that promotes the degradation of

Pulmonary embolism (9,695 words) [view diff] no match in snippet view article find links to article

renal failure. Severe cases may require thrombolysis using medication such as tissue plasminogen activator (tPA) given intravenously or through a catheter

Hereditary angioedema (4,469 words) [view diff] no match in snippet view article find links to article

is associated with mutations in genes for Factor XII, angiopoietin 1, plasminogen or kininogen 1. The pathophysiologic mechanisms contributing to bradykinin

Immunosuppressive drug (3,309 words) [view diff] no match in snippet view article find links to article

known as immunosuppressive agents, immunosuppressants and antirejection medications, are drugs that inhibit or prevent the activity of the immune system

Thrombus perviousness (1,507 words) [view diff] no match in snippet view article find links to article

crucial predictor of early recanalization with intravenous tissue-type plasminogen activator. Stroke 2015. Santos EMM, Dankbaar JW, Treurniet KM, et al

Toxic epidermal necrolysis (2,598 words) [view diff] no match in snippet view article find links to article

Meurer, WJ, Shih, R, Rosenbaum, S, Vilke, GM (December 2012). "Tissue plasminogen activator and stroke: review of the literature for the clinician". The

Plague (disease) (3,616 words) [view diff] no match in snippet view article

C, Gardner D, Long D, Hinnebusch B (2006). "Role of Yersinia pestis plasminogen activator in the incidence of distinct septicemic and bubonic forms of

Dipyridamole (1,256 words) [view diff] no match in snippet view article find links to article

arteriovenous hemodialysis grafts. It increases the release of tissue plasminogen activator from brain microvascular endothelial cells. It results in an

Thromboelastography (1,848 words) [view diff] no match in snippet view article find links to article

clinical setting. A single, modified TEG assay with exogenous tissue plasminogen activator (tPA) demonstrated remarkable efficiency in unmasking patients'

Thrombin (2,932 words) [view diff] no match in snippet view article find links to article

preparations that can be used to correct deficiencies (usually due to medication) of prothrombin. Indications include intractable bleeding due to warfarin

Hyphema (996 words) [view diff] no match in snippet view article find links to article

that they reduce the risk of rebleeding by inhibiting the conversion of plasminogen to plasmin, and thereby keeping clots stable. However, the evidence for

Cerebral infarction (3,022 words) [view diff] no match in snippet view article find links to article

primary stroke centers, pharmacologic thrombolysis with the drug tissue plasminogen activator (tPA), is used to dissolve the clot and unblock the artery

Purpura (672 words) [view diff] no match in snippet view article find links to article

sensitization". Other studies suggest the local (cutaneous) activity of tissue plasminogen activator can be increased in psychogenic purpura, leading to substantial

Disseminated intravascular coagulation (2,402 words) [view diff] no match in snippet view article find links to article

expression of various oncogenes that result in the release of TF and plasminogen activator inhibitor-1 (PAI-1), which prevents fibrinolysis. Excess circulating

Frostbite (3,621 words) [view diff] no match in snippet view article find links to article

metaanalysis revealed that iloprost alone or iloprost plus recombinant tissue plasminogen activator (rtPA) may decrease amputation rate in case of severe frostbite

Estrogen (medication) (14,549 words) [view diff] no match in snippet view article

An estrogen (E) is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy, and as part of feminizing

Uterine atony (3,241 words) [view diff] no match in snippet view article find links to article

and the placenta. Local hemostatic factors like tissue factor type-1 plasminogen activator inhibitor and platelets and clotting factors aid in stopping

Estradiol cypionate (5,105 words) [view diff] no match in snippet view article find links to article

sold under the brand name Depo-Estradiol among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen

Calciphylaxis (2,942 words) [view diff] no match in snippet view article find links to article

include one or more of the following: Clot-dissolving agents (tissue plasminogen activator) Maggot larval debridement Correction of the underlying plasma

Stroke (20,417 words) [view diff] no match in snippet view article find links to article

acute ischemic stroke. Thrombolysis, such as with recombinant tissue plasminogen activator (rtPA), in acute ischemic stroke, when given within three hours

Acute limb ischaemia (1,768 words) [view diff] no match in snippet view article find links to article

the main thrombolytic chemical. More recently, drugs such as tissue plasminogen activator, urokinase, and anistreplase have been used in their place

Abnormal uterine bleeding (1,163 words) [view diff] no match in snippet view article find links to article

inhibits synthesis of prostaglandin F2-alpha; increased levels of tissue plasminogen activator (t-PA), a fibrinolytic enzyme, lead to more fibrinolysis.[citation

Pharmacodynamics of estradiol (12,043 words) [view diff] no match in snippet view article find links to article

The pharmacology of estradiol, an estrogen medication and naturally occurring steroid hormone, concerns its pharmacodynamics, pharmacokinetics, and various

List of medical abbreviations: A (4 words) [view diff] no match in snippet view article find links to article

polyendocrine/polyglandular syndrome antiphospholipid syndrome APSAC anisoylated plasminogen streptokinase activator complex aPTT activated partial thromboplastin

Coley's toxins (2,297 words) [view diff] no match in snippet view article find links to article

(produced by killed bacteria of species Streptococcus pyogenes together with plasminogen from the patient) is the active agent of Coley's toxins. This hypothesis

Implantation (embryology) (5,851 words) [view diff] no match in snippet view article

types of cytokines modulate the activity of proteases, including MMPs, plasminogen activators, and cathepsins. It is unknown whether the cytokines involved

Drotrecogin alfa (1,675 words) [view diff] no match in snippet view article find links to article

VIIIa, and that it has indirect profibrinolytic activity by inhibiting plasminogen activator inhibitor-1 (PAI-1).[citation needed] In vitro data also suggest

Cardiovascular disease (14,421 words) [view diff] no match in snippet view article find links to article

Regarding MI, strategies using aspirin, atenolol, streptokinase or tissue plasminogen activator have been compared for quality-adjusted life-year (QALY) in

S100A10 (4,728 words) [view diff] no match in snippet view article find links to article

presented on the cell surface as a receptor for tissue-type plasminogen activator (tPA) and plasminogen. Plasmin production by many cells is dependent on p11

Myocardial infarction (13,860 words) [view diff] no match in snippet view article find links to article

administration of medication that activates the enzymes that normally dissolve blood clots. These medications include tissue plasminogen activator, reteplase

Noonan syndrome (4,191 words) [view diff] no match in snippet view article find links to article

deficiency of factor XII:C, and an imbalance of plasminogen activator inhibitor type-1 (PAI-1) and tissue plasminogen activator (t-PA) activity. It has been associated

Biomarkers of multiple sclerosis (7,797 words) [view diff] no match in snippet view article find links to article

for diagnosis of multiple sclerosis, disease evolution and response to medication (current or expected) are under research. While most of them are still

Lacunar stroke (1,711 words) [view diff] no match in snippet view article find links to article

a subcortical dementia such as Binswanger disease. Typically, tissue plasminogen activator may be administered within 3 to 4.5 hours of stroke onset if

Budd–Chiari syndrome (2,142 words) [view diff] no match in snippet view article find links to article

studies on thrombolysis with direct infusion of urokinase and tissue plasminogen activator into the obstructed vein have shown moderate success in treating

Vsevolod Tkachuk (2,107 words) [view diff] no match in snippet view article find links to article

melanoma metastasis. Research of the biological functions of urokinase-type plasminogen activator (uPA) Since early 90s V. A. Tkachuk and his colleagues (E.

Genentech (3,361 words) [view diff] no match in snippet view article find links to article

manufacturing 2004). 1987: Activase (alteplase): A recombinant tissue plasminogen activator (tPa) used to dissolve blood clots in patients with acute myocardial

Osteonecrosis of the jaw (5,176 words) [view diff] no match in snippet view article find links to article

implicated in osteoporosis. Cadmium and lead promotes the synthesis of plasminogen activator inhibitor-1 (PAI-1) which is the major inhibitor of fibrinolysis

Senolytic (2,013 words) [view diff] no match in snippet view article find links to article

dasatinib and the experimental small molecule navitoclax. Soluble urokinase plasminogen activator surface receptor have been found to be highly expressed on

Index of oncology articles (5,119 words) [view diff] no match in snippet view article find links to article

rattlesnake root – ravuconazole – rebeccamycin – recombinant tissue plasminogen activator – reconstructive surgeon – reconstructive surgery – recurrent

Heparin (7,861 words) [view diff] no match in snippet view article find links to article

Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. Heparin is a blood anticoagulant that increases

Angiotensin (3,127 words) [view diff] no match in snippet view article find links to article

Schena FP, Ursi M, Cerullo G (August 1999). "Angiotensin IV stimulates plasminogen activator inhibitor-1 expression in proximal tubular epithelial cells"

Cocaine intoxication (4,216 words) [view diff] no match in snippet view article find links to article

and adenosine diphosphate-mediated increase in platelet aggregation. Plasminogen activator inhibitor is also increased following cocaine use, thereby

Fibrinogen (3,908 words) [view diff] no match in snippet view article find links to article

accelerates by at least 100-fold the amount of plasmin activated by tissue plasminogen activator; plasmin breaks-down blood clots. Plasmin's attack on fibrin

Telehealth (19,897 words) [view diff] no match in snippet view article find links to article

Jabbour P, Gonzalez LF, et al. (October 2013). "Intravenous tissue plasminogen activator administration in community hospitals facilitated by telestroke

Hypertrophic cardiomyopathy (8,888 words) [view diff] no match in snippet view article find links to article

that have already experienced a clot. Thrombolytic agents (e.g., tissue plasminogen activator) have been used with some success to break down an existing

Factor X (3,337 words) [view diff] no match in snippet view article find links to article

vasculature. Deficiency of vitamin K or antagonism by warfarin (or similar medication) leads to the production of an inactive factor X. In warfarin therapy

Therapeutic ultrasound (2,744 words) [view diff] no match in snippet view article find links to article

delivery. Transcranial ultrasound is being tested for use in aiding tissue plasminogen activator treatment in stroke patients in the procedure called ultrasound-enhanced

Interventional radiology (13,206 words) [view diff] no match in snippet view article find links to article

which blood flow to the brain is blocked. A clot-busting medication such as tissue plasminogen activator (t-PA) can be used in a controlled hospital setting

Cerebrovascular disease (4,009 words) [view diff] no match in snippet view article find links to article

Shu-Ming (2015). "Comparison of Therapeutic Effect of Recombinant Tissue Plasminogen Activator by Treatment Time after Onset of Acute Ischemic Stroke". Scientific

Sepsis (13,537 words) [view diff] no match in snippet view article find links to article

outcomes. A 2012 systematic review found that soluble urokinase-type plasminogen activator receptor (SuPAR) is a nonspecific marker of inflammation and

Cold injury (2,854 words) [view diff] no match in snippet view article find links to article

amputation. Bone scanning can help determine the ability to use tissue plasminogen activator (tPA) for breaking up associated blood clots. In cases of suspected

Estrogen (7,508 words) [view diff] no match in snippet view article find links to article

adropin. Coagulation Increase circulating level of factors 2, 7, 9, 10, plasminogen Decrease antithrombin III Increase platelet adhesiveness Increase vWF

Lymphangioleiomyomatosis (11,094 words) [view diff] no match in snippet view article find links to article

377–8. PMID 8252188. Zhe, X; Yang, Y; Schuger, L (2005). "Imbalanced plasminogen system in lymphangioleiomyomatosis: potential role of serum response

Migrainous infarction (2,643 words) [view diff] no match in snippet view article find links to article

recommended. Alteplase is a recombinant tissue plasminogen activator which enhances the conversion of plasminogen into plasmin to aid in the degradation of

COVID-19 drug repurposing research (14,700 words) [view diff] no match in snippet view article find links to article

determined by blood levels of a protein called suPAR (soluble urokinase plasminogen activator receptor) of at least 6 ng per ml." Drugs with immune modulating

Pathophysiology of multiple sclerosis (9,023 words) [view diff] no match in snippet view article find links to article

areas coexpressed HLA-DR and VCAM-1, some others HLA-DR and urokinase plasminogen activator receptor, and others HLA-DR and ICAM-1. The damaged white matter

Side effects of bicalutamide (15,719 words) [view diff] no match in snippet view article find links to article

the nonsteroidal antiandrogen Casodex on lipoproteins, fibrinogen and plasminogen activator inhibitor in patients with benign prostatic hyperplasia". Eur

Long-term effects of alcohol (15,830 words) [view diff] no match in snippet view article find links to article

that promotes clot formation, while it increases levels of tissue type plasminogen activator, an enzyme that helps dissolve clots. These changes were estimated

Breast cancer (14,899 words) [view diff] no match in snippet view article find links to article

SCD1, for predicting response to therapeutic regimens, and urokinase plasminogen activator, PA1-1 and SCD1 for assessing prognosis.[medical citation needed]

Cocaine (17,679 words) [view diff] no match in snippet view article find links to article

formation is attributed to cocaine-associated increases in the activity of plasminogen activator inhibitor, and an increase in the number, activation, and aggregation

Deep vein thrombosis (14,621 words) [view diff] no match in snippet view article find links to article

stimulate factor Xa, cytokines that promote endothelial dysfunction, and plasminogen activator inhibitor-1, which inhibits the breakdown of clots (fibrinolysis)

Lyme disease (23,879 words) [view diff] no match in snippet view article find links to article

JL, Gebbia JA, Piesman J, Degen JL, Bugge TH, Benach JL (June 1997). "Plasminogen is required for efficient dissemination of B. burgdorferi in ticks and