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searching for Polypharmacology 13 found (29 total)

Rho kinase inhibitor (1,642 words) [view diff] exact match in snippet view article find links to article

L, Jovanovic VM, Malley C, Chu PH, et al. (May 2021). "A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent

Marc Kirschner (2,267 words) [view diff] exact match in snippet view article find links to article

Gujral, TS; Peshkin, L; Kirschner, MW (April 1, 2014). "Exploiting polypharmacology for drug target deconvolution". Proc. Natl. Acad. Sci. U.S.A. 111 (13):

Dimethylargininase (1,125 words) [view diff] exact match in snippet view article find links to article

Dimethylaminohydrolase-1 and Nitric Oxide Synthase: Toward a Targeted Polypharmacology To Control Nitric Oxide". Biochemistry. 48 (36): 8624–8635. doi:10

Ram Samudrala (1,681 words) [view diff] exact match in snippet view article find links to article

Bernard B, Samudrala R. Computational multitarget drug discovery. "Polypharmacology "263-301, 2012. Costin JM, Jenwitheesuk E, Lok S-M, Hunsperger E, Conrads

Garikapati Narahari Sastry (1,963 words) [view diff] exact match in snippet view article find links to article

(2022). "Drug repositioning for anti-tuberculosis drugs: An in silico polypharmacology approach". Molecular Diversity. 26 (3): 1675–1695. doi:10.1007/s11030-021-10296-2

Inte:Ligand (1,746 words) [view diff] exact match in snippet view article find links to article

(2013-10-01). "Computational methods for drug target profiling and polypharmacology". In Silico Drug Discovery and Design. Future Science Book Series.

Network medicine (2,563 words) [view diff] exact match in snippet view article find links to article

the drug target occupies. Combination therapy for a complex disease (polypharmacology) is suggested in this field since one active pharmaceutical ingredient

Dopamine receptor D2 (3,958 words) [view diff] exact match in snippet view article find links to article

(August 2021). "Structure-Guided Design of G-Protein-Coupled Receptor Polypharmacology". Angewandte Chemie. 60 (33): 18022–18030. doi:10.1002/anie.202101478

International Center for Ethnobotanical Education, Research and Service (3,113 words) [view diff] exact match in snippet view article find links to article

psychoactive drugs for central nervous system disorders: A perspective from polypharmacology". Current Medicinal Chemistry. 26 (1): 53–68. doi:10.2174/0929867326666191212103330

5-HT2C receptor (6,097 words) [view diff] exact match in snippet view article find links to article

2018). "5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology". Cell. 172 (4): 719–730.e14. doi:10.1016/j.cell.2018.01.001. PMC 6309861

BET inhibitor (2,514 words) [view diff] exact match in snippet view article find links to article

2014). "Dual kinase-bromodomain inhibitors for rationally designed polypharmacology". Nature Chemical Biology. 10 (4): 305–12. doi:10.1038/nchembio.1471

Peter Karl Sorger (3,097 words) [view diff] exact match in snippet view article find links to article

Sorger, P. K. (2019-08-15). "Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential

Raymond C. Stevens (5,656 words) [view diff] exact match in snippet view article find links to article

Liu “5-HT2C receptor structures reveal the structural basis of GPCR polypharmacology” Cell 172, 719-730 (2018). Online 01Feb2018. DOI: 10.1016/j.cell.2018