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searching for Protein kinase R 10 found (38 total)

GSK2606414 (284 words) [view diff] exact match in snippet view article find links to article

drug which is the first selective inhibitor discovered for the enzyme protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), which is involved in

IRF3 (1,493 words) [view diff] exact match in snippet view article find links to article

virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein". J

IRF7 (1,417 words) [view diff] exact match in snippet view article find links to article

virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein". The

Avibirnavirus (1,372 words) [view diff] exact match in snippet view article find links to article

it inhibits cellular protein synthesis through activation of the protein kinase R pathway (PKR). This activation leads to an increase in reactive oxygen

Porcine reproductive and respiratory syndrome virus 2 (2,788 words) [view diff] case mismatch in snippet view article find links to article

TRS-Bs. It has been suggested that despite the normal anti-viral role Protein Kinase R (PKR) plays in cells, type 2 PRRSV uses PKR as a pro-viral kinase within

Andes orthohantavirus (2,343 words) [view diff] exact match in snippet view article find links to article

Mir MA (February 2015). "Andes virus nucleocapsid protein interrupts protein kinase R dimerization to counteract host interference in viral protein synthesis"

Rift Valley fever (3,050 words) [view diff] exact match in snippet view article find links to article

known to affect regular activity of double-stranded RNA-dependent protein kinase R. This protein is involved in cellular antiviral responses in the host

Chikungunya (6,392 words) [view diff] exact match in snippet view article find links to article

"Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff". Journal of Virology. 85 (1): 606–20

Stress granule (12,548 words) [view diff] exact match in snippet view article find links to article

Lloyd RE (March 2015). "The stress granule protein G3BP1 recruits protein kinase R to promote multiple innate immune antiviral responses". Journal of

Myelinoid (4,897 words) [view diff] no match in snippet view article find links to article

modulator of ER stress pathways called GSK2656157, an inhibitor of protein-kinase-R-like ER kinase, partially rescued PLP1 perinuclear retention mobilizing