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searching for Ras GTPase 45 found (53 total)

alternate case: ras GTPase

RAS p21 protein activator 1 (1,605 words) [view diff] exact match in snippet view article find links to article

RAS p21 protein activator 1 or RasGAP (Ras GTPase activating protein), also known as RASA1, is a 120-kDa cytosolic human protein that provides two principal

SH3 domain (922 words) [view diff] exact match in snippet view article find links to article

been identified in several other protein families such as: PI3 Kinase, Ras GTPase-activating protein, CDC24 and cdc25. SH3 domains are found in proteins

G3BP1 (1,182 words) [view diff] exact match in snippet view article find links to article

Ras GTPase-activating protein-binding protein 1 is an enzyme that in humans is encoded by the G3BP1 gene. This gene encodes one of the DNA-unwinding enzymes

Adagrasib (806 words) [view diff] case mismatch in snippet view article find links to article

to treat non-small cell lung cancer. Adagrasib is an inhibitor of the RAS GTPase family. It is taken by mouth. It is being developed by Mirati Therapeutics

RASA3 (862 words) [view diff] exact match in snippet view article find links to article

Ras GTPase-activating protein 3 is an enzyme that in humans is encoded by the RASA3 gene. The protein encoded by this gene is member of the GAP1 family

IQGAP2 (771 words) [view diff] exact match in snippet view article find links to article

Ras GTPase-activating-like protein IQGAP2 is an enzyme that in humans is encoded by the IQGAP2 gene. This gene encodes a member of the IQGAP family. The

RASAL2 (526 words) [view diff] exact match in snippet view article find links to article

Ras GTPase-activating protein nGAP is an enzyme that in humans is encoded by the RASAL2 gene. This gene encodes a protein that contains the GAP-related

Son of Sevenless (837 words) [view diff] no match in snippet view article find links to article

GTP to GDP and phosphate. Thus, upon binding to GTP, the duration of Ras-GTPase activity depends on the rate of hydrolysis. SOS (and other guanine nucleotide

G3BP2 (518 words) [view diff] exact match in snippet view article find links to article

Ras GTPase-activating protein-binding protein 2 is an enzyme that in humans is encoded by the G3BP2 gene. G3BP2 has been shown to interact with IκBα. GRCh38:

RALB (1,603 words) [view diff] exact match in snippet view article find links to article

two paralogs of the Ral protein, the other being RalA, and part of the Ras GTPase family. RalA functions as a molecular switch to activate a number of biological

RASA4 (547 words) [view diff] exact match in snippet view article find links to article

Ras GTPase-activating protein 4 is an enzyme that in humans is encoded by the RASA4 gene. This gene encodes a member of the GAP1 family of GTPase-activating

RALA (2,012 words) [view diff] exact match in snippet view article find links to article

two paralogs of the Ral protein, the other being RalB, and part of the Ras GTPase family. RalA functions as a molecular switch to activate a number of biological

GTPase-activator protein for Ras-like GTPase (304 words) [view diff] exact match in snippet view article find links to article

is active, these proteins are said to be down-regulators of ras. The Ras GTPase-activating proteins are quite large (from 765 residues for sar1 to 3079

DLGAP4 (753 words) [view diff] no match in snippet view article find links to article

S2CID 12247592. Chen HJ, Rojas-Soto M, Oguni A, Kennedy MB (1998). "A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II". Neuron.

Btk-type zinc finger (643 words) [view diff] exact match in snippet view article find links to article

canals and of male genitalia and required for adult survival. Mammalian Ras GTPase-activating proteins (RasGAP), which regulate the activation of inactive

IQGAP1 (3,922 words) [view diff] exact match in snippet view article find links to article

Ras GTPase-activating-like protein IQGAP1 (IQGAP1) also known as p195 is a ubiquitously expressed protein that in humans is encoded by the IQGAP1 gene

RRAD (gene) (950 words) [view diff] no match in snippet view article

Caldwell JS, Kahn CR (1995). "Characterization of Rad, a new member of Ras/GTPase superfamily, and its regulation by a unique GTPase-activating protein

DNAJA3 (1,956 words) [view diff] exact match in snippet view article find links to article

homologue of the Drosophila tumor suppressor l(2)tid gene defines a novel Ras GTPase-activating protein (RasGAP)-binding protein". J. Biol. Chem. 276 (16):

HCK (2,331 words) [view diff] exact match in snippet view article find links to article

Briggs SD, Bryant SS, Jove R, Sanderson SD, Smithgall TE (Jun 1995). "The Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate

Nef (protein) (1,133 words) [view diff] no match in snippet view article

signaling takes place at the plasma membrane (PM), activation of the Ras-GTPase takes place in intracellular compartments including the Golgi apparatus

SEMA4D (1,298 words) [view diff] exact match in snippet view article find links to article

central nervous system. By binding plexin B1 receptor it functions as an R-Ras GTPase-activating protein (GAP) and repels axon growth cones in both the mature

LRRK1 (587 words) [view diff] no match in snippet view article find links to article

2.85. PMID 11347906. Bosgraaf L, Van Haastert PJ (Dec 2003). "Roc, a Ras/GTPase domain in complex proteins" (PDF). Biochim Biophys Acta. 1643 (1–3): 5–10

Julian Downward (813 words) [view diff] exact match in snippet view article find links to article

Technology. Downward's research investigates cancer biology. His work on the Ras GTPase has made seminal contributions to our understanding of how cellular signal

CAMK2G (1,113 words) [view diff] no match in snippet view article find links to article

Caldwell JS, Kahn CR (1995). "Characterization of Rad, a new member of Ras/GTPase superfamily, and its regulation by a unique GTPase-activating protein

MRAS (2,597 words) [view diff] exact match in snippet view article find links to article

"M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6". The

APBB1IP (730 words) [view diff] exact match in snippet view article find links to article

Puzon-McLaughlin W, et al. (2009). "RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences". J. Biol. Chem. 284 (8): 5119–27. doi:10

CD5 (protein) (1,469 words) [view diff] exact match in snippet view article

activation induces the association of the proto-oncoprotein c-cbl and ras GTPase-activating protein with CD5". Eur. J. Immunol. 28 (5): 1617–25. doi:10

Ras p21 protein activator 2 (222 words) [view diff] exact match in snippet view article find links to article

Venkateswarlu K, Downward J, Cullen PJ (March 1999). "Identification of the ras GTPase-activating protein GAP1(m) as a phosphatidylinositol-3,4,5-trisphosphate-binding

Caprin-1 (725 words) [view diff] no match in snippet view article find links to article

"Vaccinia virus intermediate stage transcription is complemented by Ras-GTPase-activating protein SH3 domain-binding protein (G3BP) and cytoplasmic

USP10 (1,029 words) [view diff] no match in snippet view article find links to article

DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this

Kinase (3,805 words) [view diff] exact match in snippet view article find links to article

at the level of the receptor initiates a signaling cascade whereby the Ras GTPase exchanges GDP for GTP. Next, Ras activates Raf kinase (also known as MAPKKK)

GTPase-activating protein (2,237 words) [view diff] exact match in snippet view article find links to article

1026–1032. Jin, Hongchuan et al. "Epigenetic Silencing of a Ca2+-Regulated Ras GTPase-Activating Protein RASAL Defines a New Mechanism of Ras Activation in

Alan Hall (1,975 words) [view diff] no match in snippet view article find links to article

helped uncover properties of the human p21 protein, which is encoded by N-ras. GTPase activity of different mutant forms of p21, one cloned from a patient

PASLI disease (1,244 words) [view diff] exact match in snippet view article find links to article

contains at least five domains (figure 1): adaptor-binding domain, a Ras GTPase-binding domain, a PI(3)K-type C2 domain, helical domain, and a kinase

DAB2IP (861 words) [view diff] case mismatch in snippet view article find links to article

Bergh AR, Wijers PM, Groot AJ, et al. (2004). "Identification of a novel RAS GTPase-activating protein (RASGAP) gene at 9q34 as an MLL fusion partner in a

ErbB (2,736 words) [view diff] exact match in snippet view article find links to article

the receptor tyrosine kinases generates a signaling cascade where the Ras GTPase proteins are activated to a GTP-bound state. The RAS pathway can couple

Afadin (1,982 words) [view diff] exact match in snippet view article find links to article

"M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6". The

RAC1 (3,420 words) [view diff] exact match in snippet view article find links to article

DM, Wasmuth JJ, Weissbach L, Bernards A, Snijders AJ (Sep 1996). "The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin

CDC42 (3,698 words) [view diff] exact match in snippet view article find links to article

Wasmuth JJ, Weissbach L, Bernards A, Snijders AJ (September 1996). "The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin

Huntingtin (3,255 words) [view diff] exact match in snippet view article find links to article

cytoskeleton DLG4 (PSD-95) Yes Postsynaptic Density 95 RASA1 (RasGAP) Not known Ras GTPase activating protein SH3GL3 Yes Endocytosis SIN3A Yes Transcriptional repressor

NCK1 (3,450 words) [view diff] exact match in snippet view article find links to article

Z, Valius M (October 2011). "Adaptor protein Nck1 interacts with p120 Ras GTPase-activating protein and regulates its activity". Cell. Signal. 23 (10):

List of MeSH codes (D12.776) (7,397 words) [view diff] no match in snippet view article

The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

List of MeSH codes (D12.776.476) (1,240 words) [view diff] case mismatch in snippet view article

150.300 – eukaryotic initiation factor-5 MeSH D12.776.476.325.150.500 – ras gtpase-activating proteins MeSH D12.776.476.325.150.500.460 – neurofibromin 1

List of MeSH codes (D12.644) (5,787 words) [view diff] case mismatch in snippet view article

150.300 – eukaryotic initiation factor-5 MeSH D12.644.360.325.150.500 – ras gtpase-activating proteins MeSH D12.644.360.325.150.500.460 – neurofibromin 1

Hailan Hu (2,326 words) [view diff] exact match in snippet view article find links to article

trafficking in emotional enhancement of memory formation as well as the role of Ras GTPase signalling in fragile X syndrome. In 2008, Hu returned to China and joined