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Longer titles found: Receptor tyrosine kinase-like orphan receptor (view), Related to receptor tyrosine kinase (view), AXL receptor tyrosine kinase (view), Leukocyte receptor tyrosine kinase (view), Non-receptor tyrosine kinase (view)

searching for Receptor tyrosine kinase 232 found (476 total)

alternate case: receptor tyrosine kinase

Deucravacitinib (693 words) [view diff] no match in snippet view article find links to article

Deucravacitinib, sold under the brand name Sotyktu, is medication used for the treatment of moderate-to-severe plaque psoriasis. It is a tyrosine kinase

Oclacitinib (1,384 words) [view diff] no match in snippet view article find links to article

Oclacitinib, sold under the brand name Apoquel among others, is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic

SIRPG (548 words) [view diff] exact match in snippet view article find links to article

glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants

Tofacitinib (3,189 words) [view diff] no match in snippet view article find links to article

Tofacitinib, sold under the brand Xeljanz among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis

Saracatinib (592 words) [view diff] no match in snippet view article find links to article

Saracatinib (AZD-0530) is an experimental drug being developed by AstraZeneca. It acts as a dual kinase inhibitor, with selective actions as a Src inhibitor

Globoside (562 words) [view diff] exact match in snippet view article find links to article

(GSL) was reduced in the experiment the ERK signaling from the receptor tyrosine kinase was also inhibited. The ERK was reactivated with the addition of

Phenotypic heterogeneity (133 words) [view diff] exact match in snippet view article find links to article

certain loss-of-function mutations in the RET gene, which encodes a receptor tyrosine kinase, can cause dominantly inherited failure of development of colonic

Delgocitinib (167 words) [view diff] no match in snippet view article find links to article

Delgocitinib (brand name Corectim) is a pharmaceutical drug for the treatment of autoimmune disorders and hypersensitivity, including inflammatory skin

SIRPB1 (832 words) [view diff] exact match in snippet view article find links to article

glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact

GRB14 (1,043 words) [view diff] exact match in snippet view article find links to article

growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This

Dok-7 (654 words) [view diff] exact match in snippet view article find links to article

formation of neuromuscular synapses requires the muscle-specific receptor tyrosine kinase (MuSK). In mice genetically mutant for MuSK, acetylcholine receptors

STAP2 (571 words) [view diff] exact match in snippet view article find links to article

encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation

BAIAP2 (1,415 words) [view diff] exact match in snippet view article find links to article

neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous

Cixutumumab (617 words) [view diff] exact match in snippet view article find links to article

apoptosis and may decrease cancer cellular proliferation. IGF-1R, a receptor tyrosine kinase of the insulin receptor superfamily overexpressed by many cancer

Ena/Vasp homology proteins (516 words) [view diff] exact match in snippet view article find links to article

for mutations that act as dominant suppressors of the abl non receptor tyrosine kinase. Invertebrate animals have one Ena homologue, whereas mammals have

Upadacitinib (4,534 words) [view diff] no match in snippet view article find links to article

Upadacitinib, sold under the brand name Rinvoq, is a medication used for the treatment of rheumatoid arthritis, psoriatic arthritis, atopic dermatitis

IMD domain (682 words) [view diff] exact match in snippet view article find links to article

approximately 250 amino acids found at the N-terminus in the insulin receptor tyrosine kinase substrate p53 (IRSp53/BAIAP2) and in the evolutionarily related

IRS4 (899 words) [view diff] exact match in snippet view article find links to article

SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation. IRS4 has been shown to interact with

SU6656 (277 words) [view diff] case mismatch in snippet view article find links to article

inhibitor with selectivity relative to Platelet-derived growth factor receptor Tyrosine kinase. Subsequent studies have confirmed that SU6656 is relatively selective

Bcr-Abl tyrosine-kinase inhibitor (6,383 words) [view diff] no match in snippet view article find links to article

Bcr-Abl tyrosine-kinase inhibitors (TKI) are the first-line therapy for most patients with chronic myelogenous leukemia (CML). More than 90% of CML cases

Roy S. Herbst (1,334 words) [view diff] exact match in snippet view article find links to article

College of Physicians. "Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in

ANGPT2 (1,113 words) [view diff] exact match in snippet view article find links to article

Yancopoulos GD, Suda T (August 1998). "Characterization of TEK receptor tyrosine kinase and its ligands, Angiopoietins, in human hematopoietic progenitor

Ritlecitinib (452 words) [view diff] no match in snippet view article find links to article

Ritlecitinib, sold under the brand name Litfulo, is a medication used for the treatment of severe alopecia areata (hair loss). Ritlecitinib is a kinase

Angiopoietin 1 (1,623 words) [view diff] exact match in snippet view article find links to article

H; Yancopoulos G D; Suda T (Aug 1998). "Characterization of TEK receptor tyrosine kinase and its ligands, Angiopoietins, in human hematopoietic progenitor

Neuregulin 4 (413 words) [view diff] exact match in snippet view article find links to article

the NRG4 gene. The neuregulins, including NRG4, activate erb-b2 receptor tyrosine kinase 4 (ERBB4) to initiating cell signaling through cytosolic tyrosine

Decoy receptors (686 words) [view diff] exact match in snippet view article find links to article

signal for cell death or apoptosis. VEGFR-1 is a kinase-defective receptor tyrosine kinase that negatively modulates angiogenesis by acting as a decoy receptor

FMS-like tyrosine kinase 3 ligand (724 words) [view diff] exact match in snippet view article find links to article

Zurawski S, Bazan JF, et al. (April 1994). "Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by

FIZ1 (243 words) [view diff] exact match in snippet view article find links to article

This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells

Tpr-met fusion protein (658 words) [view diff] exact match in snippet view article find links to article

Naujokas MA, Zuo D, Park M (2007). "Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr-Met, involves exclusion from the endocytic

Bronchorrhea (784 words) [view diff] exact match in snippet view article find links to article

inciting cause; they include: gefitinib - epidermal growth factor receptor tyrosine kinase inhibitor indomethacin corticosteroids octreotide radiation therapy

BPS domain (136 words) [view diff] exact match in snippet view article find links to article

crystal structure of the grb14 bps region in complex with the insulin receptor tyrosine kinase Identifiers Symbol BPS Pfam PF08947 InterPro IPR015042

Mir-210 microRNA (1,903 words) [view diff] exact match in snippet view article find links to article

modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3". The Journal of Biological Chemistry. 283 (23):

AEE788 (288 words) [view diff] exact match in snippet view article find links to article

growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity". Cancer Res

PTPN11 (4,300 words) [view diff] exact match in snippet view article find links to article

(April 2001). "Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction". Oncogene. 20 (16): 1929–38

RGS19 (1,562 words) [view diff] exact match in snippet view article find links to article

form a complex with TrkA: a putative link between G protein and receptor tyrosine kinase pathways". Mol. Biol. Cell. 12 (3). United States: 615–27. doi:10

Paul W. Sternberg (1,800 words) [view diff] exact match in snippet view article find links to article

lineages. "Multiple functions of let-23, a caenorhabditis elegans receptor tyrosine kinase gene required for vulval induction”(1991) Let-23 gene has many

Ephrin B2 (1,320 words) [view diff] exact match in snippet view article find links to article

DN, Morris SW (Apr 1996). "The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4

Growth factor receptor inhibitor (381 words) [view diff] case mismatch in snippet view article find links to article

"Efficacy of Gefitinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in Symptomatic Patients With Non–Small Cell Lung Cancer:A Randomized

Fiesselmann thiophene synthesis (841 words) [view diff] case mismatch in snippet view article find links to article

5-b]indoles as Potent Inhibitors of the Epidermal Growth Factor Receptor Tyrosine Kinase". Journal of Medicinal Chemistry. 42 (26): 5464–5474. doi:10.1021/jm9903949

SH2B1 (1,468 words) [view diff] exact match in snippet view article find links to article

"Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop". FEBS Lett. 469 (1): 72–6

GRB2-associated-binding protein 1 (1,611 words) [view diff] exact match in snippet view article find links to article

cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase". Mol. Cell. Biol. 19 (3): 1784–99. doi:10.1128/MCB.19.3.1784.

SHC1 (1,641 words) [view diff] exact match in snippet view article find links to article

locations, p66 is the longest and while the p52 and p46 link activated receptor tyrosine kinase to the RAS pathway. The protein SHC1 also acts as a scaffold protein

STAT3 (3,565 words) [view diff] exact match in snippet view article find links to article

mitogen-activated protein kinases (MAPK) and through c-src non-receptor tyrosine kinase. STAT3 mediates the expression of a variety of genes in response

Protein quaternary structure (2,342 words) [view diff] exact match in snippet view article find links to article

Another example is the receptor tyrosine kinase (RTK) pathway, which is initiated by the dimerization of two receptor tyrosine kinase monomers. When the dimer

Caveolin 3 (2,508 words) [view diff] exact match in snippet view article find links to article

J, Sargiacomo M, Lisanti MP (November 1997). "Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine

PIK3R2 (1,401 words) [view diff] exact match in snippet view article find links to article

A, et al. (June 1997). "Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site". Oncogene

MST1 (901 words) [view diff] exact match in snippet view article find links to article

YQ, Chen YQ, Fisher JH, Wang MH (2002). "Activation of the RON receptor tyrosine kinase by macrophage-stimulating protein inhibits inducible cyclooxygenase-2

Afadin (1,982 words) [view diff] exact match in snippet view article find links to article

(Aug 1998). "PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity

De'Broski R. Herbert (2,334 words) [view diff] exact match in snippet view article find links to article

Yale that aimed to determine the role that genetic ablation of a receptor tyrosine kinase encoded byTyro3in mice or the functional neutralization of its

PTPN14 (739 words) [view diff] exact match in snippet view article find links to article

phosphoprotein phosphatase activity hydrolase activity phosphatase activity receptor tyrosine kinase binding transcription coregulator activity protein binding protein

Atrophin 1 (1,921 words) [view diff] exact match in snippet view article find links to article

proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate". Human Molecular Genetics. 8 (6): 947–57. doi:10.1093/hmg/8

GFRAL (97 words) [view diff] exact match in snippet view article find links to article

binding glial cell-derived neurotrophic factor receptor activity receptor tyrosine kinase binding Cellular component integral component of membrane plasma

HYAL2 (1,152 words) [view diff] exact match in snippet view article find links to article

Lerman MI (April 2003). "Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep

Irosustat (1,564 words) [view diff] exact match in snippet view article find links to article

as a combination therapy with an oral epidermal growth factor receptor tyrosine kinase inhibitor for the treatment of Non-Small Cell Lung Cancer Patients

ZNF259 (473 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function receptor tyrosine kinase binding zinc ion binding metal ion binding protein binding translation initiation factor binding

Proterospongia (616 words) [view diff] exact match in snippet view article find links to article

Developmental Cell (2004) 7:313-325 King, N. and S. B. Carroll. 2001. A receptor tyrosine kinase from choanoflagellates: molecular insights into early animal evolution

DOK3 (500 words) [view diff] exact match in snippet view article find links to article

p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation" (PDF). J. Cell Biol. 154

SPRY3 (524 words) [view diff] exact match in snippet view article find links to article

"Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain". J

SHC2 (449 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function protein binding receptor tyrosine kinase binding Cellular component cytosol plasma membrane cellular component Biological

Collagen, type XI, alpha 1 (1,082 words) [view diff] exact match in snippet view article find links to article

Shrivastava A, Radziejewski C, Campbell E, et al. (1998). "An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors".

SH2D3A (544 words) [view diff] exact match in snippet view article find links to article

SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signaling". Gene. 391 (1–2): 161–70. doi:10.1016/j.gene.2006.12

Frizzled-2 (592 words) [view diff] exact match in snippet view article find links to article

PMID 12477932. Oishi I, Suzuki H, Onishi N, et al. (2004). "The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway"

Low-density lipoprotein receptor-related protein 4 (637 words) [view diff] exact match in snippet view article find links to article

binding protein homodimerization activity scaffold protein binding receptor tyrosine kinase binding protein binding Wnt-protein binding Wnt-activated receptor

GIPC1 (1,893 words) [view diff] exact match in snippet view article find links to article

form a complex with TrkA: a putative link between G protein and receptor tyrosine kinase pathways". Mol. Biol. Cell. 12 (3): 615–27. doi:10.1091/mbc.12

DOK5 (577 words) [view diff] exact match in snippet view article find links to article

p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation" (PDF). J Cell Biol. 154 (2):

EIF3A (1,367 words) [view diff] exact match in snippet view article find links to article

structural molecule activity translation initiation factor activity receptor tyrosine kinase binding RNA binding mRNA binding Cellular component eukaryotic

Intermediate mesoderm (1,553 words) [view diff] exact match in snippet view article find links to article

(GDNF) secreted by the metanephrogenic blastema activates the receptor tyrosine kinase RET, via the co-receptor GFRα1 and triggers outgrowth of Ret positive

DOK4 (455 words) [view diff] exact match in snippet view article find links to article

p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation" (PDF). J. Cell Biol. 154

Neuregulin 3 (2,559 words) [view diff] exact match in snippet view article find links to article

phosphorylation, and can only bind to the extracellular domain of the ERBB4 receptor tyrosine kinase but not to the other members of the ERBB family receptors; ERBB2

NUMBL (607 words) [view diff] exact match in snippet view article find links to article

et al. (1995). "A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution". Proc. Natl. Acad.

Ephrin A3 (684 words) [view diff] exact match in snippet view article find links to article

DN, Morris SW (Jan 1997). "The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4

MAPK15 (1,095 words) [view diff] exact match in snippet view article find links to article

activated by an SRC-dependent signaling pathway. SRC is a non-receptor tyrosine kinase (and proto-oncogene) that has been implicated in cancer growth

DAZAP2 (708 words) [view diff] exact match in snippet view article find links to article

function protein binding WW domain binding identical protein binding receptor tyrosine kinase binding mitogen-activated protein kinase kinase kinase binding

Ephrin A4 (667 words) [view diff] exact match in snippet view article find links to article

DN, Morris SW (Jan 1997). "The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4

SPRY1 (632 words) [view diff] exact match in snippet view article find links to article

"Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain". The

George Yancopoulos (2,391 words) [view diff] exact match in snippet view article find links to article

DeChiara TM, Bowen DC, Valenzuela DM, et al. (May 1996). "The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo"

SOCS5 (726 words) [view diff] exact match in snippet view article find links to article

growth factor receptor binding protein kinase inhibitor activity receptor tyrosine kinase binding protein binding 1-phosphatidylinositol-3-kinase regulator

ETV1 (711 words) [view diff] exact match in snippet view article find links to article

ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu". The Journal of Biological Chemistry. 279 (15): 14909–16

List of drugs granted breakthrough therapy designation (180 words) [view diff] exact match in snippet view article find links to article

neurotrophic receptor tyrosine kinase (NTRK) gene fusion Larotrectinib Bayer Healthcare solid tumors that have a neurotrophic receptor tyrosine kinase (NTRK)

LRIG1 (763 words) [view diff] exact match in snippet view article find links to article

M, Paratcha G (2008). "Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF"

Alexander Levitzki (902 words) [view diff] case mismatch in snippet view article find links to article

Rabinovich, Laura; Levitzki, Alexander; Gertz, S. David (1998). "PDGF-Receptor Tyrosine Kinase Blocker AG1295 Selectively Attenuates Smooth Muscle Cell Growth

Angela Vincent (839 words) [view diff] exact match in snippet view article find links to article

Melms, Arthur; Vincent, Angela (2001). "Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor

TNFAIP1 (499 words) [view diff] exact match in snippet view article find links to article

Marks RM, et al. (1995). "Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis". Science. 268 (5210): 567–9

DUSP3 (979 words) [view diff] exact match in snippet view article find links to article

protein tyrosine phosphatase activity cytoskeletal protein binding receptor tyrosine kinase binding protein tyrosine kinase binding Cellular component cytosol

BCR (gene) (1,541 words) [view diff] exact match in snippet view article

M, Winkler A, Kolb HJ, et al. (July 1996). "Interaction of the receptor tyrosine kinase p145c-kit with the p210bcr/abl kinase in myeloid cells". British

ANGPT4 (679 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function receptor tyrosine kinase binding transmembrane receptor protein tyrosine kinase activator activity Cellular component

GIPC3 (860 words) [view diff] exact match in snippet view article find links to article

of WNT receptor, insulin-like growth factor-I receptor (IGF1R), receptor tyrosine kinase TrkA, TGF-beta type III receptor (TGF-beta RIII), integrin alpha6A

Pediatric ependymoma (4,967 words) [view diff] exact match in snippet view article find links to article

metallothioneins are associated with recurrence in ependymomas. KIT receptor tyrosine kinase and phospho-KIT were found to be present in pediatric ependymomas

SH3BP4 (600 words) [view diff] exact match in snippet view article find links to article

et al. (1995). "A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution". Proc. Natl. Acad.

Quinazoline (1,240 words) [view diff] exact match in snippet view article find links to article

Raymond E, Faivre S, Armand J (2000). "Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy". Drugs. 60 Suppl 1: 15–23,

TRIM33 (1,047 words) [view diff] exact match in snippet view article find links to article

transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas". Oncogene. 18 (30):

Collagen, type V, alpha 2 (1,121 words) [view diff] exact match in snippet view article find links to article

Shrivastava A, Radziejewski C, Campbell E, et al. (1998). "An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors".

DOK2 (1,058 words) [view diff] exact match in snippet view article find links to article

p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation" (PDF). J. Cell Biol. 154

Bradykinin receptor B2 (1,311 words) [view diff] exact match in snippet view article find links to article

"Bradykinin enhances GLUT4 translocation through the increase of insulin receptor tyrosine kinase in primary adipocytes: evidence that bradykinin stimulates the

CHARGE study (653 words) [view diff] exact match in snippet view article find links to article

link between both exposure to air pollution, a variant in the MET receptor tyrosine kinase gene and risk of autism. Maternal use of folic acid supplements

GIPC3 (860 words) [view diff] exact match in snippet view article find links to article

of WNT receptor, insulin-like growth factor-I receptor (IGF1R), receptor tyrosine kinase TrkA, TGF-beta type III receptor (TGF-beta RIII), integrin alpha6A

ANGPT4 (679 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function receptor tyrosine kinase binding transmembrane receptor protein tyrosine kinase activator activity Cellular component

ELMO2 (742 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function SH3 domain binding receptor tyrosine kinase binding protein binding Cellular component cytosol membrane cytoplasm Biological

Mitogen (1,700 words) [view diff] exact match in snippet view article find links to article

abnormally low levels of mitogens. One such example is HER2, a receptor tyrosine kinase that responds to the mitogen EGF. Overexpression of HER2 is common

CD2 (1,432 words) [view diff] exact match in snippet view article find links to article

signaling receptor activity antigen binding protein kinase binding receptor tyrosine kinase binding protein self-association Cellular component integral component

RGS1 (854 words) [view diff] case mismatch in snippet view article find links to article

Form a Complex with TrkA: A Putative Link between G Protein and Receptor Tyrosine Kinase Pathways". Mol. Biol. Cell. 12 (3): 615–27. doi:10.1091/mbc.12

TRIM24 (1,301 words) [view diff] exact match in snippet view article find links to article

transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas". Oncogene. 18 (30):

Lipofibromatosis-like neural tumor (2,198 words) [view diff] exact match in snippet view article find links to article

the development and/or progression of LPF-NTs. Two inhibitors of receptor tyrosine kinase activity, larotrectinib and entrectinib, have been shown to be

RNF41 (647 words) [view diff] exact match in snippet view article find links to article

ubiquitin-protein transferase activity protein domain specific binding receptor tyrosine kinase binding ubiquitin protein ligase activity Cellular component cytosol

BCAR3 (943 words) [view diff] exact match in snippet view article find links to article

SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signaling". Gene. 391 (1–2): 161–70. doi:10.1016/j.gene.2006.12

YopH, N-terminal (793 words) [view diff] exact match in snippet view article find links to article

nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila". Dev. Biol. 180 (1): 63–81. doi:10.1006/dbio

Ephrin A1 (860 words) [view diff] exact match in snippet view article find links to article

DN, Morris SW (Apr 1996). "The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4

MTSS1 (745 words) [view diff] exact match in snippet view article find links to article

actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein". J. Biol. Chem

CNKSR1 (836 words) [view diff] exact match in snippet view article find links to article

encoded by the CNKSR1 gene. This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is

PITPNM1 (949 words) [view diff] exact match in snippet view article find links to article

binding phospholipid transporter activity calcium ion binding receptor tyrosine kinase binding phosphatidylcholine transporter activity Cellular component

PIK3R3 (896 words) [view diff] exact match in snippet view article find links to article

Alindri F, Karlsson R, Dahlbäck B (2003). "Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology

PTPN1 (2,731 words) [view diff] exact match in snippet view article find links to article

receptor binding phosphatase activity ephrin receptor binding receptor tyrosine kinase binding zinc ion binding protein binding protein tyrosine phosphatase

HRBL (545 words) [view diff] exact match in snippet view article find links to article

et al. (1995). "A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution". Proc. Natl. Acad.

Barry V. L. Potter (2,584 words) [view diff] exact match in snippet view article find links to article

as a combination therapy with an oral epidermal growth factor receptor tyrosine kinase inhibitor for the Treatment of Non-Small Cell Lung Cancer Patients

List of human clusters of differentiation (467 words) [view diff] exact match in snippet view article find links to article

Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment

CBLC (847 words) [view diff] exact match in snippet view article find links to article

binding ubiquitin-protein transferase activity transferase activity receptor tyrosine kinase binding zinc ion binding protein binding Cellular component plasma

CEACAM1 (1,472 words) [view diff] exact match in snippet view article find links to article

recombinant pp120/HA4, an endogenous substrate of the insulin receptor tyrosine kinase". Biochemistry. 34 (29): 9341–9. doi:10.1021/bi00029a009. PMID 7626603

Joachim Drevs (481 words) [view diff] case mismatch in snippet view article find links to article

PTK787/ZK 222584, a Specific Vascular Endothelial Growth Factor-Receptor Tyrosine Kinase Inhibitor, Affects the Anatomy of the Tumor Vascular Bed and the

Discoidin domain (723 words) [view diff] exact match in snippet view article find links to article

PMC 386597. PMID 3092220. Rutter WJ, Edman JC, Johnson JD (1993). "A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin

SH2D3C (976 words) [view diff] exact match in snippet view article find links to article

SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signaling". Gene. 391 (1–2): 161–70. doi:10.1016/j.gene.2006.12

MAP3K7 (1,695 words) [view diff] exact match in snippet view article find links to article

binding MAP kinase kinase kinase activity identical protein binding receptor tyrosine kinase binding Cellular component cytosol membrane plasma membrane endosome

SHC3 (1,085 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function receptor tyrosine kinase binding signal transducer activity protein binding phosphotyrosine residue binding Cellular component

Matuzumab (842 words) [view diff] exact match in snippet view article find links to article

domain III of the extracellular domain of the EGFR. The EGFR is receptor tyrosine kinase which binds multiple growth factors including EGF (epidermal growth

FRS3 (734 words) [view diff] exact match in snippet view article find links to article

SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways". Oncogene. 25 (49): 6457–66. doi:10.1038/sj

SH2D3C (976 words) [view diff] exact match in snippet view article find links to article

SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signaling". Gene. 391 (1–2): 161–70. doi:10.1016/j.gene.2006.12

Tony Pawson (biochemist) (1,188 words) [view diff] exact match in snippet view article

Letwin, K.; Pawson, T. (1994). "Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis"

PTPN2 (1,202 words) [view diff] exact match in snippet view article find links to article

binding non-membrane spanning protein tyrosine phosphatase activity receptor tyrosine kinase binding hydrolase activity protein tyrosine phosphatase activity

Joachim Drevs (481 words) [view diff] case mismatch in snippet view article find links to article

PTK787/ZK 222584, a Specific Vascular Endothelial Growth Factor-Receptor Tyrosine Kinase Inhibitor, Affects the Anatomy of the Tumor Vascular Bed and the

GFRA1 (1,493 words) [view diff] exact match in snippet view article find links to article

Vecchio G, Pinto A, Grieco M (Apr 1997). "Expression of the RET receptor tyrosine kinase and GDNFR-alpha in normal and leukemic human hematopoietic cells

Phonemic neurological hypochromium therapy (525 words) [view diff] exact match in snippet view article find links to article

Davis CM, Vincent JB: Chromium oligopeptide activates insulin receptor tyrosine kinase activity. Biochemistry 36: 4382–4385, 1997 4. Sun Y, Ramirez J

Caveolin 1 (1,551 words) [view diff] exact match in snippet view article find links to article

J, Sargiacomo M, Lisanti MP (November 1997). "Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine

Regional differentiation (5,170 words) [view diff] exact match in snippet view article find links to article

The terminalia are specified through the action of the Torso receptor tyrosine kinase. The follicle cells secrete Torso-like into the perivitelline space

Christopher Marshall (doctor) (924 words) [view diff] exact match in snippet view article

PMC 4442819. PMID 25979981. Marshall, CJ (January 1995). "Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated

RANBP9 (1,266 words) [view diff] exact match in snippet view article find links to article

Alindri F, Karlsson R, Dahlbäck B (2003). "Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology

PLXNB1 (1,248 words) [view diff] exact match in snippet view article find links to article

(2004). "Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2". J. Cell Biol. 165 (6): 869–80. doi:10.1083/jcb.200312094

Thomas N. Sato (589 words) [view diff] exact match in snippet view article find links to article

(October 1993). "Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system". Proc. Natl

Fibro-adipose vascular anomaly (842 words) [view diff] exact match in snippet view article find links to article

called PIK3CA in some—but not all—cases. PIK3CA is a gene in the receptor tyrosine kinase phosphatidylinositol 3-kinase (PI3)-AKT growth-signaling pathway

MAGED1 (1,202 words) [view diff] exact match in snippet view article find links to article

Kuroda Y, Komori T, Sasaki A, Watanabe K, Minami Y (2003). "The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family

PIK3C2B (1,114 words) [view diff] exact match in snippet view article find links to article

Toyoshima H, Hagiwara K, Yazaki Y, Hirai H (Oct 1994). "Human ltk receptor tyrosine kinase binds to PLC-gamma 1, PI3-K, GAP and Raf-1 in vivo". Oncogene.

Gamma secretase (2,207 words) [view diff] exact match in snippet view article find links to article

"gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase". Science. 294 (5549): 2179–81. doi:10.1126/science.1065412. PMID 11679632

CDC40 (810 words) [view diff] exact match in snippet view article find links to article

et al. (1995). "A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution". Proc. Natl. Acad.

Dedicator of cytokinesis protein 4 (1,495 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function SH3 domain binding receptor tyrosine kinase binding PDZ domain binding protein binding guanyl-nucleotide exchange factor

Chordoma (2,179 words) [view diff] exact match in snippet view article find links to article

SJ, Cates JM (February 2008). "Immunohistochemical analysis of receptor tyrosine kinase signal transduction activity in chordoma". Neuropathology and Applied

GOPC (1,213 words) [view diff] exact match in snippet view article find links to article

Charest A, Lane K, McMahon K, et al. (2003). "Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21)". Genes

GDF15 (1,339 words) [view diff] exact match in snippet view article find links to article

family receptor alpha-like (GFRAL) and the recruitment of the receptor tyrosine kinase RET in the hindbrain. In both mice and humans have shown that metformin

NRXN2 (766 words) [view diff] exact match in snippet view article find links to article

et al. (1998). "PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity

Copine 3 (555 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function protein binding receptor tyrosine kinase binding protein serine/threonine kinase activity calcium-dependent protein binding

Synaptojanin (1,135 words) [view diff] exact match in snippet view article find links to article

to neuronal migration. Ephrin's receptor is called Eph and is a receptor tyrosine kinase. Upon activation of the Eph receptor, synaptojanin 1 becomes phosphorylated

ABCB5 (1,864 words) [view diff] exact match in snippet view article find links to article

melanoma- initiating cells were demonstrated to express FLT1 (VEGFR1) receptor tyrosine kinase which was functionally required for efficient xenograft tumor formation

NRXN3 (1,103 words) [view diff] exact match in snippet view article find links to article

et al. (1998). "PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity

NCK2 (1,551 words) [view diff] exact match in snippet view article find links to article

Alindri F, Karlsson R, Dahlbäck B (Dec 2002). "Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology

LIM domain (1,963 words) [view diff] exact match in snippet view article find links to article

internalization motif (InsRF) at LIM domain 3. LIM domain 2 binds Ret receptor tyrosine kinase. This protein is localized in the cytoplasm and nucleus. It is

Thomas Tüting (470 words) [view diff] case mismatch in snippet view article find links to article

Tüting T, Hölzel M. "Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy.”, Immunity”, Oct 17;47(4):789-802

CARD-CC family (1,414 words) [view diff] case mismatch in snippet view article find links to article

"CARMA3 Is a Critical Mediator of G Protein-Coupled Receptor and Receptor Tyrosine Kinase-Driven Solid Tumor Pathogenesis". Frontiers in Immunology. 9: 1887

Joy Wolfram (1,112 words) [view diff] exact match in snippet view article find links to article

Centre, Toronto, Canada, in 2010, investigating antiangiogenic receptor tyrosine kinase inhibitors. Wolfram began working as a research fellow for cancer

TOB1 (1,287 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function receptor tyrosine kinase binding SMAD binding protein binding transcription corepressor activity Cellular component CCR4-NOT

EPS8 (1,480 words) [view diff] exact match in snippet view article find links to article

A, Wong WT, Di Fiore PP, Simeone A (1995). "Expression of the receptor tyrosine kinase substrate genes eps8 and eps15 during mouse development". Oncogene

PTPN6 (2,292 words) [view diff] exact match in snippet view article find links to article

Birchmeier C, Böhmer FD (January 2001). "Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine

RAS p21 protein activator 1 (1,605 words) [view diff] exact match in snippet view article find links to article

1998). "Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking site for SH2-domain mediated interactions"

MiR-138 (2,962 words) [view diff] exact match in snippet view article find links to article

CCND3 BCR (breakpoint cluster region)-ABL (c-abl oncogene 1, non-receptor tyrosine kinase)/GATA1/miR-138 mini circuitry contributes to the leukemogenesis

Cyclin H (1,468 words) [view diff] exact match in snippet view article find links to article

Wong TW (Jan 1994). "Identification and chromosomal mapping of a receptor tyrosine kinase with a putative phospholipid binding sequence in its ectodomain"

MiR-138 (2,962 words) [view diff] exact match in snippet view article find links to article

CCND3 BCR (breakpoint cluster region)-ABL (c-abl oncogene 1, non-receptor tyrosine kinase)/GATA1/miR-138 mini circuitry contributes to the leukemogenesis

Christine Lovly (794 words) [view diff] exact match in snippet view article find links to article

include alterations in the protein Anaplastic Lymphoma Kinase (ALK) receptor tyrosine kinase. When this protein is altered, there is potential for pharmaceuticals

DNAJA3 (1,956 words) [view diff] exact match in snippet view article find links to article

hyperthickened skin. DNAJA3 has been shown to interact with: ErbB-2 receptor tyrosine kinase MK5 HSPA9 HSPA8, JAK2, and RASA1 ENSG00000103423 GRCh38: Ensembl

CBLB (gene) (1,393 words) [view diff] exact match in snippet view article

ubiquitin-protein transferase activity transferase activity SH3 domain binding receptor tyrosine kinase binding ubiquitin protein ligase activity zinc ion binding Cellular

ADAM10 (2,466 words) [view diff] exact match in snippet view article find links to article

YW, Koski R, Varnum B, Liu ET (January 1995). "The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage"

Receptor for activated C kinase 1 (2,598 words) [view diff] exact match in snippet view article find links to article

ontology Molecular function protein homodimerization activity receptor tyrosine kinase binding SH2 domain binding signaling adaptor activity protein tyrosine

Papillary renal cell carcinoma (3,726 words) [view diff] exact match in snippet view article find links to article

upregulated for renal tissue repair and regeneration by encoding the receptor tyrosine kinase c-MET of hepatocyte growth factor. However, activation of the oncogenic

Sequestosome 1 (1,644 words) [view diff] exact match in snippet view article find links to article

ontology Molecular function protein homodimerization activity receptor tyrosine kinase binding zinc ion binding SH2 domain binding metal ion binding protein

Weatherall Institute of Molecular Medicine (1,188 words) [view diff] exact match in snippet view article find links to article

Melms, Arthur; Vincent, Angela (2001). "Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor

Paraptosis (2,767 words) [view diff] exact match in snippet view article find links to article

human colorectal cancer cells following overactivation of the non-receptor tyrosine kinase c-Src suggesting potential involvement of Src-signalling in paraptosis

YWHAG (1,363 words) [view diff] exact match in snippet view article find links to article

growth factor receptor binding protein domain specific binding receptor tyrosine kinase binding protein binding protein kinase C binding protein kinase

Annexin A5 (1,645 words) [view diff] exact match in snippet view article find links to article

calcium transporter activity heparin binding peptide hormone binding receptor tyrosine kinase binding molecular adaptor activity Cellular component membrane

FNTA (1,005 words) [view diff] exact match in snippet view article find links to article

activity microtubule binding Rab geranylgeranyltransferase activity receptor tyrosine kinase binding alpha-tubulin binding protein farnesyltransferase activity

JAG1 (2,693 words) [view diff] exact match in snippet view article find links to article

K (1998). "PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity

Chinmoy Sankar Dey (2,169 words) [view diff] exact match in snippet view article find links to article

kinase) could be stopped by inhibiting the activity of the insulin receptor tyrosine kinase, which was a new discovery. His research has been documented in

Neuromuscular junction disease (2,417 words) [view diff] exact match in snippet view article find links to article

Newsom-Davis J, Melms A, Vincent A (2001). "Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor

Edison Liu (885 words) [view diff] exact match in snippet view article find links to article

isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase". Molecular and Cellular Biology. 11 (10): 5016–5031. doi:10.1128/mcb

13-Methyltetradecanoic acid (1,078 words) [view diff] no match in snippet view article find links to article

M; Gilbert DR & Kolch W (2005). "Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway". The Biochemical Journal. 392 (Pt 2): 249–61

STAT5A (1,831 words) [view diff] exact match in snippet view article find links to article

Beckman BS, Marrero L, Jones FE (November 2004). "The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone"

Tasquinimod (1,511 words) [view diff] exact match in snippet view article find links to article

vascular endothelial growth factor (VEGF) neutralization or VEGF receptor tyrosine kinase inhibition. A randomized, double-blind, placebo-controlled phase

Stem cell marker (5,679 words) [view diff] exact match in snippet view article find links to article

of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase". Blood. 90 (1): 111–25. PMID 9207445. Pfeilstöcker M, Karlic H

Inflammatory breast cancer (2,651 words) [view diff] exact match in snippet view article find links to article

Cristofanilli M, Liu P, et al. (November 2009). "Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits

Allorecognition (1,889 words) [view diff] exact match in snippet view article find links to article

vertebrates. In sponges, various receptors (sponge adhesion molecules, receptor tyrosine kinase) with domains similar to those found in immunoglobulins have been

A. Thomas Look (1,392 words) [view diff] exact match in snippet view article find links to article

Look, A Thomas (10 June 2012). "Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia". Nature Medicine. 18 (7): 1118–1122

Myocilin (2,124 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function frizzled binding receptor tyrosine kinase binding myosin light chain binding protein binding fibronectin binding metal

James O. McNamara (1,313 words) [view diff] exact match in snippet view article find links to article

His work has demonstrated that seizure-induced activation of the receptor tyrosine kinase B (TrkB) by its ligand Brain Derived Neurotrophic Factor (BDNF)

Myocilin (2,124 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function frizzled binding receptor tyrosine kinase binding myosin light chain binding protein binding fibronectin binding metal

John J. M. Bergeron (1,182 words) [view diff] case mismatch in snippet view article find links to article

M.; Posner, B.I. (2016). "Spatial and Temporal Regulation of Receptor Tyrosine Kinase Activation and Intracellular Signal Transduction". Annu Rev Biochem

VEGFR-2 inhibitor (4,735 words) [view diff] exact match in snippet view article find links to article

VEGFR-2 is a highly active kinase while VEGFR1 is an impaired receptor tyrosine kinase. This receptor is a regulator in responses in the endothelial cells

Choanoflagellate (4,055 words) [view diff] exact match in snippet view article find links to article

PMC 3574361. PMID 23407828. King N, Carroll SB (December 2001). "A receptor tyrosine kinase from choanoflagellates: molecular insights into early animal evolution"

Carlo M. Croce (2,532 words) [view diff] exact match in snippet view article find links to article

Kenneth P.; Croce, Carlo M. (2022). "Retraction Note: EGFR and MET receptor tyrosine kinase–altered microRNA expression induces tumorigenesis and gefitinib

Fluorescence-lifetime imaging microscopy (3,093 words) [view diff] exact match in snippet view article find links to article

Bastiaens, Philippe I.H. (1999). "Fluorescence lifetime imaging of receptor tyrosine kinase activity in cells". Current Biology. 9 (19): 1127–30. doi:10

Laboratory rat (3,648 words) [view diff] exact match in snippet view article find links to article

H.; LaVail, M. M.; Vollrath, D. (March 2000). "Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat". Human Molecular

PAX3 (4,371 words) [view diff] exact match in snippet view article find links to article

NRCAM Intercellular adhesion Chemokine receptor CXCR4 Motility Receptor tyrosine kinase FGFR4 Proliferation, differentiation, migration MET Proliferation

CCDC180 (1,228 words) [view diff] exact match in snippet view article find links to article

Neuroblastoma RAS viral oncogene homolog Regulates cell division Erb-B2 receptor tyrosine kinase 2 Stabilizes ligand binding in other EGF receptor family members

MACPF (2,332 words) [view diff] exact match in snippet view article find links to article

also contains a MACPF domain. Its function is implicated in a receptor tyrosine kinase signaling pathway that specifies differentiation and terminal cell

Somatic evolution in cancer (9,909 words) [view diff] exact match in snippet view article find links to article

gene targeted by the drugs, and amplification of MET, another receptor tyrosine kinase, which can bypass EGFR to activate downstream signaling in the

The Cancer Genome Atlas (7,468 words) [view diff] exact match in snippet view article find links to article

High mutation burden; 76% of tumors demonstrated activation of receptor tyrosine kinase pathways Lung Squamous Cell Carcinoma 178 High average number of

Myasthenia gravis (5,999 words) [view diff] exact match in snippet view article find links to article

Jenkins NA, Burden SJ, Glass DJ, Yancopoulos GD (September 1995). "Receptor tyrosine kinase specific for the skeletal muscle lineage: expression in embryonic

Sodium–potassium pump (4,510 words) [view diff] exact match in snippet view article find links to article

For example, the Na+-K+ pump interacts directly with Src, a non-receptor tyrosine kinase, to form a signaling receptor complex. Src is initially inhibited

Protein Wnt-5a (3,402 words) [view diff] exact match in snippet view article find links to article

factor activity chemoattractant activity involved in axon guidance receptor tyrosine kinase-like orphan receptor binding signaling receptor binding cytokine

ZCCHC18 (1,669 words) [view diff] case mismatch in snippet view article find links to article

Gingras AC, Stagljar I (January 2017). "A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome". Molecular Cell. 65 (2): 347–360

BAG3 (3,610 words) [view diff] exact match in snippet view article find links to article

"Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop". FEBS Lett. 469 (1): 72–6

Brain-derived neurotrophic factor (5,339 words) [view diff] exact match in snippet view article find links to article

in either the presence of a specific NR2B antagonist or a trk receptor tyrosine kinase inhibitor. Thus, it appears BDNF can upregulate the expression

SorCS2 (2,321 words) [view diff] exact match in snippet view article find links to article

with proBDNF (brain-derived neurotrophic factor) and TrkB (BDNF receptor tyrosine kinase) inside neurons in the hippocampal region of the brain to modulate

Kaposi's sarcoma-associated herpesvirus (5,238 words) [view diff] exact match in snippet view article find links to article

Neipel F, Fleckenstein B, Hahn A, et al. (June 2012). "The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma-associated herpesvirus"

Ghanaian bat henipavirus (2,732 words) [view diff] exact match in snippet view article find links to article

receptor ephrin-B2. Ephrin-B2 is a transmembrane cellular surface receptor tyrosine kinase responsible for bi-directional signaling during tumorigenesis and

SBK3 (2,118 words) [view diff] exact match in snippet view article find links to article

confidence). This ligand is functionally annotated to bind to a receptor tyrosine kinase called the hepatocyte growth factor receptor. The location of SBK3's

Proliferating cell nuclear antigen (6,158 words) [view diff] exact match in snippet view article find links to article

MutLalpha complex binding identical protein binding enzyme binding receptor tyrosine kinase binding DNA binding DNA polymerase binding damaged DNA binding

Igor Stagljar (1,674 words) [view diff] exact match in snippet view article find links to article

Gingras, A-C., and Stagljar, I. (2017) A global analysis of the receptor tyrosine kinase - protein phosphatase interactome, Molecular Cell 65, 347-360.

Vitamin K (7,769 words) [view diff] exact match in snippet view article find links to article

"Gas6 and protein S. Vitamin K–dependent ligands for the Axl receptor tyrosine kinase subfamily". The FEBS Journal. 273 (23): 5231–44. doi:10.1111/j

Development of the nervous system (6,860 words) [view diff] exact match in snippet view article find links to article

proteins act as receptors for NGF and related factors. Trk is a receptor tyrosine kinase. Trk dimerization and phosphorylation leads to activation of various

Glioblastoma (8,526 words) [view diff] exact match in snippet view article find links to article

pathway involves the amplification and mutational activation of receptor tyrosine kinase (RTK) genes, leading to the dysregulation of growth factor signaling

Glioblastoma (8,526 words) [view diff] exact match in snippet view article find links to article

pathway involves the amplification and mutational activation of receptor tyrosine kinase (RTK) genes, leading to the dysregulation of growth factor signaling

Breast development (6,495 words) [view diff] exact match in snippet view article find links to article

mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase". J. Biol. Chem. 279 (3): 1713–9. doi:10.1074/jbc.M306156200. PMID 14593113

Gene therapy of the human retina (4,699 words) [view diff] exact match in snippet view article find links to article

Surgeons (RCS) in rat model shows that a recessive mutation in a receptor tyrosine kinase gene, mertk results in a premature stop codon and impaired phagocytosis

NUMB (gene) (4,144 words) [view diff] exact match in snippet view article

et al. (1995). "A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution". Proc. Natl. Acad.

Personalized medicine (9,820 words) [view diff] exact match in snippet view article find links to article

non-small cell lung cancer patients with epidermal growth factor receptor tyrosine kinase inhibitors". Journal of Thoracic Oncology. 7 (1): 40–8. doi:10

Oncogenomics (7,682 words) [view diff] exact match in snippet view article find links to article

tumor progression: an internal tandem duplication of the FLT3 receptor tyrosine kinase gene, which activates kinase signaling and is associated with a

Hepatocellular carcinoma (9,623 words) [view diff] exact match in snippet view article find links to article

Baradari V, Schuppan D, Scherübl H (May 2006). "Blockade of IGF-1 receptor tyrosine kinase has antineoplastic effects in hepatocellular carcinoma cells".

TMEM267 (1,931 words) [view diff] case mismatch in snippet view article find links to article

Villedieu, A., … Stagljar, I. (2017). A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. Molecular cell, 65(2), 347–360

Epithelioid sarcoma (5,913 words) [view diff] exact match in snippet view article find links to article

antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase". Cancer Research. 62 (9): 2554–60. PMID 11980649. Carmeliet, Peter;

Malú G. Tansey (2,796 words) [view diff] exact match in snippet view article find links to article

intracellular signalling component of the GFL receptor system, the receptor tyrosine kinase RET. They found that in order for proper RET function and thus

Single-cell sequencing (8,539 words) [view diff] exact match in snippet view article find links to article

compound mutations present in amplified therapeutic targets such as receptor tyrosine kinase genes (EGFR, PDGFRA etc.) where conventional population-level approaches

Mutation (13,965 words) [view diff] exact match in snippet view article find links to article

sequences between the Fused in Glioblastoma (FIG) gene and the receptor tyrosine kinase (ROS), producing a fusion protein (FIG-ROS). The abnormal FIG-ROS

Treatment of lung cancer (6,487 words) [view diff] exact match in snippet view article find links to article

Manzoni M; Delfanti S; et al. (March 2007). "Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small-cell lung cancer: results

Precambrian body plans (4,539 words) [view diff] exact match in snippet view article find links to article

PMID 18273011. King, Nicole; Carrol, Sean B. (September 10, 2001). "A receptor tyrosine kinase from choanoflagellates: Molecular insights into early animal evolution"

Dominant white (10,969 words) [view diff] exact match in snippet view article find links to article

to the KIT gene in 2007. KIT is short for "KIT proto-oncogene receptor tyrosine kinase". White spotting is caused by multiple forms, or alleles, of the

G-quadruplex (11,903 words) [view diff] exact match in snippet view article find links to article

pathway exudes a necessity for baseline transcription of this receptor tyrosine kinase. In certain types of cancers, the RET protein has shown increased

TMEM211 (9,001 words) [view diff] case mismatch in snippet view article find links to article

Transmembrane Leucine Zipper Is Required for Activation of the Dimeric Receptor Tyrosine Kinase DDR1". Journal of Biological Chemistry. 281 (32): 22744–22751.

Mastocytoma in dogs (5,633 words) [view diff] no match in snippet view article find links to article

of which are functionally most important: The stem cell factor receptor (tyrosine kinase KIT) regulates mast cell differentiation, proliferation, activation