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searching for STAT1 74 found (171 total)

alternate case: sTAT1

Interleukin-21 receptor (864 words) [view diff] exact match in snippet view article find links to article

activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for
IFN1@ (529 words) [view diff] exact match in snippet view article find links to article
signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C". Biochem. J. 379 (Pt 1): 199–208
Oncostatin M (4,317 words) [view diff] exact match in snippet view article find links to article
(YLPQ), Y915 (YMPQ). The lower propensity for STAT1 activation may be a reflection of the lower number of STAT1 activation sequences, YZPQ (where X is any
ChIP sequencing (3,353 words) [view diff] exact match in snippet view article find links to article
affinities of a protein to different DNA sites. STAT1 DNA association: ChIP-seq was used to study STAT1 targets in HeLa S3 cells which are clones of the
Interleukin 35 (1,669 words) [view diff] exact match in snippet view article find links to article
TNF-α). The effect of IL-35 in this case seems to be the inhibition of STAT1 signalling pathway. Another experiment performed on a mouse model of EAE
PTPN2 (1,206 words) [view diff] case mismatch in snippet view article find links to article
Jesus Ibarra-Sanchez M, Fu Y, et al. (2002). "Identification of a nuclear Stat1 protein tyrosine phosphatase". Mol. Cell. Biol. 22 (16): 5662–8. doi:10
Fibroblast growth factor receptor 4 (1,289 words) [view diff] case mismatch in snippet view article find links to article
Z, Zhong Z, Darnell JE (1995). "Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation". Cell. 82 (2):
IFNA2 (2,608 words) [view diff] exact match in snippet view article find links to article
factors, namely STAT1 and STAT2, members of the family Signal Transducer and Activator of Transcription (STAT protein); phosphorylated STAT1 and STAT2 bind
Envelope glycoprotein GP120 (2,547 words) [view diff] exact match in snippet view article find links to article
oxidative stress in the neuronal cells, and it is also known to activate STAT1 and induce interleukins IL-6 and IL-8 secretion in neuronal cells. HIV envelope
N-myc-interactor (1,163 words) [view diff] case mismatch in snippet view article find links to article
M, Leonard WJ (Mar 1999). "Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling". Cell. 96 (1): 121–30. doi:10
Bufotalin (825 words) [view diff] exact match in snippet view article find links to article
2012). "Bufotalin sensitizes death receptor-induced apoptosis via Bid- and STAT1-dependent pathways" (PDF). International Journal of Oncology. 40 (1): 203–8
List of MeSH codes (D12.776.930) (1,091 words) [view diff] case mismatch in snippet view article
500.750 – hepatocyte nuclear factor 1-beta MeSH D12.776.930.354.249.500 – stat1 transcription factor MeSH D12.776.930.354.249.750 – stat2 transcription
Mir-145 (1,481 words) [view diff] exact match in snippet view article find links to article
Frankel LB, et al. (2010). Kudla G (ed.). "MicroRNA-145 targets YES and STAT1 in colon cancer cells". PLOS ONE. 5 (1): e8836. Bibcode:2010PLoSO...5.8836G
Thanatophoric dysplasia (852 words) [view diff] exact match in snippet view article find links to article
(FGFR3), which activates signal transducer and activator of transcription 1 (STAT1) from the endoplasmic reticulum". J. Biol. Chem. 278 (19): 17344–9. doi:10
Pitrakinra (780 words) [view diff] exact match in snippet view article find links to article
pro-inflammatory mediators induce nitric oxide synthase (iNOS) through STAT1 and STAT6 in epithelial cells. Basal FENO could be more dependent on up-regulation
Beena Pillai (855 words) [view diff] exact match in snippet view article find links to article
polyglutamine toxicity of TATA-box binding protein is mediated through STAT1 in mouse neuronal cells". Journal of Neuroinflammation. 14 (1): 155. doi:10
Xin Lu (1,005 words) [view diff] exact match in snippet view article find links to article
Constantinescu, Stefan N.; Ansorge, Olaf; Stolp, Helen B. (2014-07-08). "STAT1-induced ASPP2 transcription identifies a link between neuroinflammation
MCM7 (1,647 words) [view diff] case mismatch in snippet view article find links to article
of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma". Proc. Natl
DUSP3 (979 words) [view diff] case mismatch in snippet view article find links to article
blocks gamma interferon signal transduction: viral VH1 phosphatase reverses Stat1 activation". J. Virol. 75 (7): 3185–96. doi:10.1128/JVI.75.7.3185-3196.2001
MCM2 (1,600 words) [view diff] case mismatch in snippet view article find links to article
of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma". Proc. Natl
CAMK2D (872 words) [view diff] case mismatch in snippet view article find links to article
DaFonseca CJ, Tjernberg A, et al. (2002). "Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma". Proc. Natl. Acad. Sci
CAMK2G (1,113 words) [view diff] case mismatch in snippet view article find links to article
Z, Zhong Z, Darnell JE (1995). "Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation". Cell. 82 (2):
MAGEH1 (493 words) [view diff] exact match in snippet view article find links to article
"Transcriptional up-regulation of restin by all-trans retinoic acid through STAT1 in cancer cell differentiation process". Biochem. Biophys. Res. Commun.
CD200 (1,801 words) [view diff] exact match in snippet view article find links to article
shown that CD200 expression is induced by IFN-γ and TNF-α in a NF-kappaB, STAT1 and IRF-1 dependent manner Soluble CD200 (sCD200) is present in serum. It
Autocrine signaling (2,105 words) [view diff] exact match in snippet view article find links to article
also contributes to maintenance of EMT, possibly through activation of STAT1 and other distinct pathways. In addition, expression of PDGFRα and -β correlated
IL2RB (1,698 words) [view diff] exact match in snippet view article find links to article
Delespine-Carmagnat M, Bouvier G, Bertoglio J (January 2000). "Association of STAT1, STAT3 and STAT5 proteins with the IL-2 receptor involves different subdomains
MCM3 (1,553 words) [view diff] case mismatch in snippet view article find links to article
of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma". Proc. Natl
Rhabdoviridae (2,776 words) [view diff] exact match in snippet view article find links to article
factor 3 (IRF3)  and signal transducer and activator of transcription 1 (STAT1), thus eliminating the cellular type 1 interferon pathway. Also, P protein
DDB1 (1,415 words) [view diff] exact match in snippet view article find links to article
damage repair binding protein is essential for the targeted degradation of STAT1 by the V protein of the paramyxovirus simian virus 5". J. Virol. 76 (22):
Murine norovirus (829 words) [view diff] exact match in snippet view article find links to article
-receptor. Karst SM, Wobus CE, Lay M, Davidson J, Virgin HW (March 2003). "STAT1-dependent innate immunity to a Norwalk-like virus". Science. 299 (5612):
WWTR1 (2,383 words) [view diff] exact match in snippet view article find links to article
Nuclear shuttling; promoting transcription STAT1, Signal transducer and activator of transcription Inhibiting STAT1/2 dimerization in metabolism TEAD1, TEA
Interleukin-7 receptor-α (840 words) [view diff] exact match in snippet view article find links to article
lymphoblastic leukemia cells and murine BAF3 cells involves activation of STAT1 and STAT5 mediated via the interleukin-7 receptor alpha chain". Leukemia
Lateral body (447 words) [view diff] exact match in snippet view article find links to article
cellular immune response through MAPK signaling pathways. H1 dephosphorylates STAT1 to prevent nuclear transcription and block IFNy-induced immune signaling
MAPK14 (5,259 words) [view diff] exact match in snippet view article find links to article
targets of p38α MAPK, including ATF1/2/6, c-Myc, c-FOS, GATA4, MEF2A/C, SRF, STAT1, and CHOP p38α MAPK constitutes the main p38 MAPK activity in heart. During
PYR-41 (220 words) [view diff] exact match in snippet view article find links to article
II-induced activation of dendritic cells via the IκBa/NF-κB and MKP1/ERK/STAT1 pathways". Immunology. 142 (2): 307–319. doi:10.1111/imm.12255. PMC 4008238
List of MeSH codes (D12.776.476) (1,240 words) [view diff] case mismatch in snippet view article
interferon-stimulated gene factor 3, alpha subunit MeSH D12.776.476.024.381.500.500 – stat1 transcription factor MeSH D12.776.476.024.381.500.750 – stat2 transcription
Endogenous retrovirus (8,298 words) [view diff] exact match in snippet view article find links to article
with ERVs bound by signal transducer and activator of transcription 1 (STAT1) and/or Interferon regulatory factor (IRF1) in CD14+ macrophages. HERVs
Endogenous retrovirus (8,298 words) [view diff] exact match in snippet view article find links to article
with ERVs bound by signal transducer and activator of transcription 1 (STAT1) and/or Interferon regulatory factor (IRF1) in CD14+ macrophages. HERVs
CSRP2 (629 words) [view diff] exact match in snippet view article find links to article
stellate cells and binding partner of the protein inhibitor of activated STAT1". Biochem. J. 359 (Pt 3): 485–96. doi:10.1042/0264-6021:3590485. PMC 1222169
Glycoprotein 130 (2,202 words) [view diff] exact match in snippet view article find links to article
(1997). "Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor
Perlecan (11,011 words) [view diff] exact match in snippet view article find links to article
intact STAT1 transcription factor was required for the signal to take effect. This led the investigators to believe that the transcription factor STAT1 was
List of MeSH codes (D12.644) (5,787 words) [view diff] case mismatch in snippet view article
interferon-stimulated gene factor 3, alpha subunit MeSH D12.644.360.024.301.500.500 – stat1 transcription factor MeSH D12.644.360.024.301.500.750 – stat2 transcription
Coronavirus nucleocapsid protein (2,547 words) [view diff] exact match in snippet view article find links to article
interferon signaling by suppressing phosphorylation and nuclear translocation of STAT1 and STAT2". Cell Discovery. 6 (1): 65. doi:10.1038/s41421-020-00208-3. PMC 7490572
Rabies virus (4,259 words) [view diff] case mismatch in snippet view article find links to article
Mechanisms to Escape the IFN System: The Viral Protein P Interferes with IRF-3, Stat1, and PML Nuclear Bodies". Journal of Interferon & Cytokine Research. 26
Creative Biolabs (951 words) [view diff] case mismatch in snippet view article find links to article
Doroshow, James H. (2011-04-08). "Up-regulation and Sustained Activation of Stat1 Are Essential for Interferon-γ (IFN-γ)-induced Dual Oxidase 2 (Duox2) and
Georgette D. Kanmogne (2,345 words) [view diff] exact match in snippet view article find links to article
chemokine receptor mediated HIV-1 binding to HBMECs and that cross talk between STAT1 and PI3K pathways were mediating the BBB dysfunction after HIV infection
List of distinct cell types in the adult human body (1,208 words) [view diff] exact match in snippet view article find links to article
memory CD45RA unknown unknown Blood None None unknown None CD3D, TRAC, IL4R, STAT1, MAL, SOCS1, IL2, ODC1, PSAT1, WARS, PYCR1, TNF, NME1 CD4 T cell effector
MIR7-1 (737 words) [view diff] exact match in snippet view article find links to article
ameliorates age-associated loss of fibroblast function by attenuating IFN-γ/STAT1-dependent miR-7 upregulation". Aging Cell. 15 (3): 531–41. doi:10.1111/acel
SLFN5 (300 words) [view diff] exact match in snippet view article find links to article
Platanias LC (October 2017). "Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma"
Hani Gabra (576 words) [view diff] exact match in snippet view article find links to article
resistance from laboratory to clinic; such targets include AKT, MTOR, HDAC4, STAT1 and the Folate Receptors. Until September 2017 he was founding President
Bunyaviridae nonstructural S proteins (852 words) [view diff] exact match in snippet view article find links to article
severe fever with thrombocytopenia syndrome virus through inhibition of STAT1 phosphorylation and activation". Journal of General Virology. 96 (11): 3204–3211
List of MeSH codes (D12.776.157) (4,484 words) [view diff] case mismatch in snippet view article
interferon-stimulated gene factor 3, alpha subunit MeSH D12.776.157.057.061.500.500 – stat1 transcription factor MeSH D12.776.157.057.061.500.750 – stat2 transcription
Arbutus unedo (4,124 words) [view diff] exact match in snippet view article find links to article
Shoji, K.; Suzuki, H. (2008). "Aqueous extract of Arbutus unedo inhibits STAT1 activation in human breast cancer cell line MDA-MB-231 and human fibroblasts
STAT5A (1,831 words) [view diff] case mismatch in snippet view article find links to article
Leonard WJ (January 1999). "Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling". Cell. 96 (1): 121–30. doi:10
PRMT1 (1,751 words) [view diff] exact match in snippet view article find links to article
Schurter BT, Shuai K, Herschman HR, David M (2001). "Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription". Cell. 104 (5): 731–41. doi:10
Heat shock protein 90kDa alpha (cytosolic), member A1 (8,175 words) [view diff] exact match in snippet view article
explaining the pro-survival ability of NF-κB-driven transcription. Conversely, STAT1, the proto-tumor suppressor, is found to inhibit stress induced expression
Tumor-associated macrophage (2,424 words) [view diff] exact match in snippet view article find links to article
by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation)". Blood. 107 (5): 2112–22. doi:10.1182/blood-2005-01-0428. PMID 16269622
TATA box (4,785 words) [view diff] exact match in snippet view article find links to article
polyglutamine toxicity of TATA-box binding protein is mediated through STAT1 in mouse neuronal cells". Journal of Neuroinflammation. 14 (1): 155. doi:10
ROSAH syndrome (696 words) [view diff] exact match in snippet view article find links to article
constructs have shown immune activation with increased NF-κB signaling, STAT1 phosphorylation and interferon gene expression signature. This condition
Histone deacetylase 2 (4,587 words) [view diff] exact match in snippet view article find links to article
role in regulating the Signal Transducer and Activator of Transcription I (STAT1) and interferon-stimulated gene such as viperin. This shows that HDAC2 might
William Paul Duprex (2,008 words) [view diff] exact match in snippet view article find links to article
Mutation, E95D, in the Mumps Virus V Protein Disengages STAT3 Targeting from STAT1 Targeting". Journal of Virology. 83 (13): 6347–6356. doi:10.1128/JVI.00596-09
Antibody microarray (3,156 words) [view diff] case mismatch in snippet view article find links to article
S2CID 2753950. Wang Y., Wu T. R., Cai S., Welte T., Chin Y. E. (2000). "Stat1 as a Component of Tumor Necrosis Factor Alpha Receptor 1-TRADD Signaling
SCRIB (2,159 words) [view diff] exact match in snippet view article find links to article
response suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity suppression by virus of host JAK-STAT cascade via inhibition of
Tumor microenvironment (6,813 words) [view diff] exact match in snippet view article find links to article
by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation)". Blood. 107 (5): 2112–2122. doi:10.1182/blood-2005-01-0428
List of human clusters of differentiation (467 words) [view diff] exact match in snippet view article find links to article
activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. CD361 Also known as EVI2B. CD362 Also known as SDC2, Syndecan-2
SNX8 (4,216 words) [view diff] exact match in snippet view article find links to article
gamma, which takes places parallelly to the more known IFNγ-induced JAK-STAT1 mediated pathway. Overall, it participates in a series of chemical reactions
Michael P. Snyder (2,263 words) [view diff] exact match in snippet view article find links to article
A.; Marra, M.; Snyder, M.; Jones, S. (2007). "Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel
Lymphangioleiomyomatosis (11,094 words) [view diff] exact match in snippet view article find links to article
uncontrolled LAM cell growth and increases LAM cell viability. Upregulation of STAT1 and STAT3 and autophagy are known mediators of LAM cell viability and survival
Smoker's macrophages (2,982 words) [view diff] exact match in snippet view article find links to article
oxidative stress would be reduced. In post-smoke situations, reduction in STAT1 is associated with M1-like phenotype and the downregulation of IFN-γ signaling
Mihai Netea (2,194 words) [view diff] exact match in snippet view article find links to article
Graaf CA, Kullberg BJ, van der Meer JW, Lilic D, Veltman JA, Netea MG. STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis. N Engl
Stress granule (12,548 words) [view diff] exact match in snippet view article find links to article
Subunit ST7 ST7/FAM4A1/HELG/RAY1/TSG7 Suppression Of Tumorigenicity 7 yes STAT1 STAT1 Signal transducer and activator of transcription 1-alpha/beta STAU1 Staufen
Carla V. Rothlin (2,682 words) [view diff] exact match in snippet view article find links to article
cytokine-dependent TAM signalling is upregulated by type I interferon-STAT1 signalling leading to expression of cytokine and TLR suppressors, acting
Stefano Pluchino (2,014 words) [view diff] case mismatch in snippet view article find links to article
"Extracellular vesicles from neural stem cells transfer IFN-g via Ifngr1 to activate Stat1 signalling in target cells". Molecular Cell. 56 (2): 193–204. doi:10.1016/j
List of human transcription factors (81 words) [view diff] exact match in snippet view article find links to article
Inferred motif from similar protein – High-throughput in vitro [884] VAAGTTT STAT1 ENSG00000115415 STAT Known motif – In vivo/Misc source [885] HTTCCYRGAAR