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Longer titles found: Coronavirus spike protein (view)

searching for Spike protein 123 found (265 total)

alternate case: spike protein

Walvax COVID-19 vaccine (1,441 words) [view diff] exact match in snippet view article find links to article

targets the Sars-CoV-2 receptor-binding domain of the spike protein, rather than the entire spike protein. It is approved for Phase III trials in China, Mexico

NDV-HXP-S comes from the terms Newcastle disease virus, HexaPro, and spike protein. The stabilization of the S protein of SARS-CoV-2 (HexaPro) was achieved

Adenovirus and encodes for SARS-COV-2 full length prefusion stabilized Spike protein. More specifically, the vector used is the simian group C adenovirus

commonly known as the spike protein, of the viral particle responsible for the COVID-19 pandemic. The ectodomain region of the spike protein (S) is essential

seven-turn helix that reaches 34 Å (3.4 nm) long. The P22 phage tail spike protein, a component of the P22 bacteriophage, has 13 turns and in its assembled

a protein are monoclonal protein, M protein, M component, M spike, spike protein, or paraprotein. This proliferation of the myeloma protein has several

Pemirolast has appeared as a possible candidate for SARS-CoV-2 (COVID-19) spike protein disruption and interference. Such results were ascertained by molecular

used in efforts for public health initiatives such as sequencing the spike protein from SARS-CoV-2 as well as for the surveillance of norovirus outbreaks

disease. Tamibarotene is found to have inhibitory potential for the viral spike protein of Omicron variant of SARS-CoV2 and can be a potential candidate for

Vaccine Research Center to design a stabilized version of the SARS-CoV-2 spike protein, which biotechnology company Moderna used as the basis for the vaccine

number NCT04982068 for "Phase I Clinical Trial of Recombinant SARS-CoV-2 Spike Protein Vaccine (CHO Cell)" at ClinicalTrials.gov Clinical trial number NCT04990544

RH-BAT-Cov-HKU2 shares a common evolutionary origin in the spike protein of Bat-SARS CoV. This spike protein shares similar deletions with group 2 coronaviruses

epitope peptides covering the entire viral proteome except for the spike protein, which was covered with 253 15-mer peptides overlapping by 10 residues

epitope peptides covering the entire viral proteome except for the spike protein, which was covered with 253 15-mer peptides overlapping by 10 residues

Sc-BatCoV-512 shares a common evolutionary origin in the spike protein of Bat-SARS CoV. This spike protein shares similar deletions with group 2 coronaviruses

encoded by the MSN gene. Moesin (for membrane-organizing extension spike protein) is a member of the ERM protein family which includes ezrin and radixin

[citation needed] The host-cell-expressed basigin (CD147) may bind spike protein of SARS-CoV-2 and possibly be involved in host cell invasion. Subsequently

protective immune response to IBV is poorly understood, but the surface spike protein, the amino-terminal S1 half, is sufficient to induce good protective

SARS-CoV-2 spike protein (S-Trimer) combined with one of two different adjuvants AS03 (GlaxoSmithKline) or CpG/Alum (Dynavax). The vaccine displays the spike protein

receptor-mediated endocytosis by the host cells. The glycoprotein (G) is a trimeric spike protein that extends through the virus's envelope and can interact with surface

spike protein of SARS-CoV-2 human bamlanivimab/etesevimab SARS-CoV-2 coronavirus causing the COVID-19 pandemic immunotherapy, targets spike protein of

broad set of antigens against SARS-CoV-2 that includes both stabilized spike protein and highly conserved viral protein regions containing T cell epitopes

Dall'Asta C (2020). "Preventing the Interaction between Coronaviruses Spike Protein and Angiotensin I Converting Enzyme 2: An in Silico Mechanistic Case

vedotin mab chimeric/ humanized CD319 cancer Bamlanivimab mab human spike protein receptor binding domain (RBD) of SARS-CoV-2 Emergency Use Authorization

major contributor to vaccine hesitancy. Syncytin-1 and the SARS-CoV-2 spike protein targeted by the vaccines are largely dissimilar, sharing a sequence

control mechanism. Her research team identified that the SARS-CoV-2 spike protein could bind linoleic acid. Berger-Schaffitzel studied biochemistry in

lineage C viruses in bats reveals marked sequence divergence in the spike protein of Pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: Implications

is a "monovalent COVID-19-specific vaccine expressing the SARS-CoV-2 spike protein". By March 9, the initial Phase 1/2 study of VBI-2902 was underway.

SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein". Current Biology. 30 (11): 2196–2203.e3. doi:10.1016/j.cub.2020.05

expressed the SARS-CoV2 spike protein once inside human cells to elicit an immune response. She measured IgG and IgM spike protein antibody response and

and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19 Vaccine) in Adults". jrct.niph.go.jp. Japan Registry of Clinical

(April 2022). "The Chimeric Adenovirus (Ad5/35) Expressing Engineered Spike Protein Confers Immunity against SARS-CoV-2 in Mice and Non-Human Primates"

SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein". Current Biology. 30 (11): 2196–2203.e3. doi:10.1016/j.cub.2020.05

Olvera de la Cruz and Qiao found that the binding of the SARS-CoV-2 spike protein receptor-binding domain (RBD) to the human cell receptor hACE2 can be

infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion". Cell Research

processes at a molecule scale. It enabled to quickly understand the spike protein structure of the SARS-CoV-2 virus. Richard R. Ernst, contributions towards

discovered that "adding two prolines to a key joint of a vaccine's spike protein could stabilize the structure's prefusion shape" (patent WO2018081318A1)

formed by pseudotyping contain the native form of the viral Envelope (or Spike) protein, but may not contain other structural elements from the original virus

Infectious Peritonitis is Determined by Mutations in the Feline Coronavirus Spike Protein". Journal of Virology. 79 (22): 14122–30. doi:10.1128/JVI.79.22.14122-14130

SARS-CoV-2. NVX-CoV2373 is a protein subunit vaccine that contains the spike protein of the SARS-CoV-2 virus. Novavax's work is in competition for vaccine

vaccine, and led an all-woman team. After Patel received the SARS-CoV-2 spike protein in February 2020, she designed and characterized over twenty variants

and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19 Vaccine) in Adults". jrct.niph.go.jp. Japan Registry of Clinical

Major capsid protein G 60 in virion Major spike protein H 12 in virion DNA pilot protein (or minor spike protein) J 60 in virion Binds to new single-stranded

and some human and SARS-like coronaviruses. Most of these affect the spike protein and it is thought the virus could have undergone genetic recombination

for t…" (Tweet) – via Twitter. "Researchers analyse Omicron variant's spike protein at EPFL imaging lab". Sciencebusiness. 4 January 2022. Retrieved 30

infection, and instead acts as a vector to transfer the SARS-CoV-2 spike protein. The spike protein, an external protein that enables the virus to enter cells

HIV. Protein-based vaccines for COVID-19 tend to target either its spike protein or its receptor binding domain. As of 2021, the most researched vaccine

interactions) HPRD (protein interactions) BioGRID (protein interactions) SPIKE (protein interactions, signaling reactions) WikiPathways (metabolic and signaling

Austin, Newcastle disease virus (NDV) viral vector (expressing the spike protein of SARS-CoV-2, with or without the adjuvant CpG 1018) or Inactivated

which the ability of this compound to bind with high affinity to the spike protein of SARS-CoV-2 has been demonstrated, an early step towards drug development

the 3M Young Scientist Challenge, due to her endeavor to identify the spike protein of the SARS-CoV-2. In 2021, Sarah Park from Jacksonville, Florida won

significant risk of spillover, in southern China, based on data from spike protein sequences, infectious clone technology, infection experiments (both

Spanish camels had protein-specific antibodies against the MERS-CoV spike protein. Blood serum from European sheep, goats, cattle, and other camelids

vital role in host cell-virus fusion activation by priming virus's Spike protein to show the protein named "fusion protein" (TMPRSS2 activate SARS-CoV-2

appear to be associated with a nucleoprotein.[citation needed] The spike protein (VP4) is glycosylated. The lipid envelope is similar to its host's composition

compound for SARS-CoV-2 inhibition with the highest docking scores for the spike protein and Mpro. Thymoquinone is a phytochemical compound found in the plant

Reoviruses have a unique structure which is contains a glycolisated spike protein on the surface. The genomes of viruses in family Reoviridae contain

score from a sonification algorithm and the structure of the virus' S (spike) protein. Beyond the aesthetic appeal of the outcome of the analysis, it may

score from a sonification algorithm and the structure of the virus' S (spike) protein. Beyond the aesthetic appeal of the outcome of the analysis, it may

PMID 20402623. Salvatori G, Luberto L, and Marra E (2020). "SARS-CoV-2 SPIKE PROTEIN: an optimal immunological target for vaccines". Journal of Translational

institute also discovered an emerging lineage with N440K mutation in spike protein associated with immune escape. A comprehensive suite for computational

vector, which stimulates an immune response against the coronavirus spike protein. Plans were announced to start animal studies in March 2020, and recruitment

adenovirus-vectored vaccine (ChAdOx1 nCoV-19) expressing the SARS-CoV-2 spike protein." Several subjects needed prophylactic paracetamol to minimize their

monomeric receptor binding domain subunit, residues 331-530 of the Spike protein of SARS-CoV-2 strain 156 Wuhan-Hu-1, expressed in the yeast Pichia pastoris

Inside the coronavirus there is a spike protein that can penetrate human cells. Addo looks to combine the spike protein with the genetic information of

Amino acid changes located in the receptor binding domain of the S1 spike protein region, involved in the adsorption to the cellular receptor (sialic

is a "monovalent COVID-19-specific vaccine expressing the SARS-CoV-2 spike protein". By March 9, the initial Phase 1/2 study of VBI-2902 was underway.

position 501 or position 498 but not both) in the SARS-CoV-2 virus spike protein can mouse-adapt the novel Coronavirus. Some animals which were only

"Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate". Human Vaccines

due to the molecular clamp being derived from fragments of Gp41, the spike protein of HIV, leading to "a partial antibody response" to HIV. This is an

Schneider et al. CovRadar - for molecular surveillance of the Corona spike protein De-Leon and Pederiva - A dynamic particle Monte Carlo algorithm based

to accurately predict the atomic-scale structure of the SARS-CoV-2 spike protein weeks before it could be measured in the lab. On June 26 of 2020, the

analysis predicts ritonavir and naloxegol strongly block the SARS-CoV-2 spike protein-hACE2 binding". Journal of Biomolecular Structure & Dynamics. 40 (4):

more towards interactions between the virus and the host cell such as spike protein characteristics. Monkeypox virus is relatively large compared to other

vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses"

Christopher T.; Miller, Jeff F. (2014-04-01). "The Type VI secretion system spike protein VgrG5 mediates membrane fusion during intercellular spread by pseudomallei

traffics to GM1 lipid rafts where it is localized with the palmitoylated spike protein of SARS-CoV-2 and primes it for viral entry. (ACE2) (target Cell, viral

used as a booster vaccine. The vaccine is designed to target both the spike protein of the SARS‑CoV‑2 virus, and viral proteins that may be less prone to

vaccines are toxic fails to account for key differences between the spike protein produced during infection and vaccination, misrepresents studies". Health

nucleotide genetic sequence uniquely matching a part of the SARS-CoV-2 spike protein three years prior to the pandemic, arguing it was evidence that the

anti-SARS-CoV-2 mAb, in complex with the Receptor-Binding-Domain of the Spike protein (Plos Path. 2022,e1010994) So far, he has been centrally involved in

A diagram of the HIV spike protein (green), with the fusion peptide epitope highlighted in red, and a broadly neutralizing antibody (yellow) binding to

Che; Wong, Chi-Huey; et al. (2022-04-06). "Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal

methodology to find lead molecules that can selectively bind to the spike protein of the SARS-CoV-2 virus. America's Top Young Scientist of the Year,

vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses"

(2021). "LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein". bioRxiv 10.1101/2021.09.25.461776. Song J, Chow RD, Pena-Hernandez

(Pfizer–BioNTech) demonstrate a greater T cell response against in-frame spike protein than those receiving Vaxzevria (Oxford–AstraZeneca), despite the latter

theories and misinformation (e.g. the COVID-19 pandemic was planned, the spike protein causes cell death, medical authorities are conspiring to illegitimately

TrimericS IgG test. The test was developed using the full length SARS-CoV-2 Spike protein in its Trimeric form, which perfectly mimics the native conformation

F.; Lees, J. G.; Santini, J. M.; Orengo, C. A. (2020). "SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from

brain cancers. Nanobodies that tightly bind to the RBD domain of the spike protein of betacoronaviruses (including SARS-CoV-2 which causes COVID-19) and

recombinant measles vaccine as a vector for introducing SARS-CoV-2 spike protein into the body. Merck acquired Themis in June 2020 and abandoned all

research group prospectively identified mutations in the SARS-CoV-2 spike protein that erode the immunity provided by both therapeutic antibodies and

Procko to work on mimicking the part of the ACE2 protein where the spike protein binds as decoys that bind to the virus and prevent it from interacting

SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein". Current Biology. 30 (11): 2196–2203.e3. Bibcode:2020CBio...30E2196Z

enters into AT II cells by binding to ACE 2 surface receptors with its spike protein. Keijzers GB (April 2001). "Aviptadil (Senatek)". Current Opinion in

Autologous dendritic cells previously loaded ex-vivo with SARS-CoV-2 spike protein. Subjects eligible for treatment will be those who at baseline, are

potential phytochemicals and their effects on the complex of SARS-CoV2 spike protein and human ACE2". Scientific Reports. 10 (1): 17699. Bibcode:2020NatSR

described their experiments splicing the SARS-CoV-2 BA.1 Omicron's spike protein into an ancestral SARS-CoV-2 variant isolated in the early days of the

Example of a phylogenetic tree created from an alignment of 250 unique spike protein sequences from the Betacoronavirus family.

Institute, New York City: Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing

vaccines were either "poisoning Americans" or "putting miniature Covid-19 spike protein factories in our arms to wreak havoc with ovaries and balls". Both claims

10 June 2021. "A study of the safety of EDV nanocells packaged with spike-protein plasmid and glycolipid as a COVID-19 vaccine in healthy volunteers"

2020). "Sea Urchin Pigments as Potential Therapeutic Agents Against the Spike Protein of SARS-CoV-2 Based on in Silico Analysis". doi:10.26434/chemrxiv.12568595

infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion". Cell Research

a Seattle-based company that had been selling a purported "nCoV19 spike protein vaccine". On 21 January 2021, its founder, Johnny Stine, was arrested

versions of Tachyon were used to render images of the SARS-CoV-2 virion, spike protein, and aerosolized virion in three separate ACM Gordon Bell COVID-19 research

assays that use a harmless virus modified to express the SARS-CoV-2 Spike protein and a fluorescent reporter - she could then test for the presence of

of the 5' untranslated regions; it contains an open reading frame, spike protein, accessory proteins, envelope protein, membrane protein, nucleocapsid

position 501 or position 498 (but not both) in the SARS-CoV-2 virus spike protein would adapt the novel Coronavirus to mice. In January 2021, the mice

which initially bind to receptors on the bacterial cell wall and a tail spike protein that subsequently binds irreversibly to other receptors on the cell

protein subunit vaccine from Medigen, and a DNA vaccine encoding the spike protein from Inovio.” More countries are expected to join the program. The first

nucleotide genetic sequence uniquely matching a part of the SARS-CoV-2 spike protein three years prior to the pandemic, arguing it was evidence that the

include ACE2 and co-receptor TMPRSS2. TMPRSS2 is needed to cleave the spike protein for viral fusion to cell membrane. However, a recent study has demonstrated

the few points of the binding domain (RBD) of the receptor binding of spike protein and host cell receptor ACE2. "Civet SARS CoV 007/2004". Uniprot. Xing-Yi

been able to present the receptor binding domain of the SARS-CoV-2 spike protein to invoke an immune response in mice. A stable AP205 VLP was designed

been able to present the receptor binding domain of the SARS-CoV-2 spike protein to invoke an immune response in mice. A stable AP205 VLP was designed

Patel, SK; Klein, J; Rashimi, P; Dhama, K (2021-07-21). "SARS-CoV-2 Spike Protein Extrapolation for COVID Diagnosis and Vaccine Development". Frontiers

Pfizer–BioNTech COVID-19 vaccine could cause infertility because the SARS-CoV-2 spike protein shared a sequence of four base pairs with syncytin-1, has also come

2022). "Antibody Evaluation and Mutations of Antigenic Epitopes in the Spike Protein of the Porcine Epidemic Diarrhea Virus from Pig Farms with Repeated

chief, Viral Pathogenesis Lab, Vaccine Research Center; co-designed spike protein with Moderna for the COVID-19 vaccine James Tayloe Gwathmey (M.D. 1899)

SARS-CoV-2 contains natural Insertions at the S1/S2 cleavage site of the spike protein". Current Biology. 30 (11): 2196–2203. Bibcode:2020CBio...30E2196Z.

September 2022. Retrieved 6 October 2022. "Implications of mutations in the spike protein of Danish mink-derived SARS-CoV-2 isolates for vaccines and monoclonal