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searching for TRPA1 35 found (92 total)

alternate case: tRPA1

TRPA (ion channel) (805 words) [view diff] exact match in snippet view article

family is made up of 7 subfamilies: TRPA1, TRPA- or TRPA1-like, TRPA5, painless, pyrexia, waterwitch, and HsTRPA. TRPA1 is the only subfamily widely expressed
Dicentrine (146 words) [view diff] exact match in snippet view article find links to article
antinociceptive activity in a mouse model of pain. It probably acts via a TRPA1-dependent mechanism. Huang, Ray-Ling; Chen, Chien-Chih; Huang, Yu-Lin; Ou
AM-1241 (696 words) [view diff] exact match in snippet view article find links to article
release of endogenous opioid peptides, as well as direct activation of the TRPA1 channel. It has also shown efficacy in the treatment of amyotrophic lateral
Diallyl disulfide (2,785 words) [view diff] exact match in snippet view article find links to article
perceived through the transient receptor potential cation channel, member A1 (TRPA1). This ion channel had long been present not only in humans and animals
Urodacus manicatus (785 words) [view diff] exact match in snippet view article find links to article
purposes. This cell-penetrating peptide selectively activates mammalian TRPA1 receptors, which are expressed in pain-sensing peripheral neurons, to produce
Infrared sensing in vampire bats (2,139 words) [view diff] exact match in snippet view article find links to article
channels, including TRPV1 (transient receptor potential vanilloid) and TRPA1 (transient receptor potential cation channel A1), is important in thermal
AMG-517 (466 words) [view diff] exact match in snippet view article find links to article
and Non-histaminergic Itch Mediators: Respective Involvement of TRPV1 and TRPA1". Neuroscience. 449: 35–45. doi:10.1016/j.neuroscience.2020.09.048. PMC 8219216
Transient receptor potential calcium channel family (1,621 words) [view diff] exact match in snippet view article find links to article
or long TRPs, ankyrin (whose only member is the transmembrane protein 1 [TRPA1]) TRPN after the nonmechanoreceptor potential C (nonpC), and the more distant
Oleocanthal (1,346 words) [view diff] exact match in snippet view article find links to article
as hypothesized by Beauchamp et al.." Oleocanthal is an activator of the TRPA1 ion channel, which is activated by ibuprofen. Oleocanthal is found to be
Hexachloroethane (761 words) [view diff] exact match in snippet view article find links to article
Mückter, H., Thiermann, H., Gudermann, T. (2018). Zinc chloride-induced TRPA1 activation does not contribute to toxicity in vitro. Toxicology Letters
Antifeedant (491 words) [view diff] exact match in snippet view article find links to article
Patapoutian, Ardem (May 24, 2005). "The Pungency of Garlic: Activation of TRPA1 and TRPV1 in Response to Allicin" (PDF). Current Biology. 15 (10): 929–34
Monarda fistulosa (1,381 words) [view diff] exact match in snippet view article find links to article
Chemical Composition and Activation of Transient Receptor Potential A1 (TRPA1) Channels". Molecules. 25 (21): 4873. doi:10.3390/molecules25214873. PMC 7659962
Cinnamon challenge (1,417 words) [view diff] exact match in snippet view article find links to article
vasomotor manifestations of individual and combined stimulation of TRPM8 and TRPA1 using topical L-menthol and trans-cinnamaldehyde in healthy volunteers"
Odontoblast (1,319 words) [view diff] exact match in snippet view article find links to article
has been shown that odontoblast-neuron signal communication via Piezo1/TRPA1 channels and pannexin-1 in odontoblasts and P2X3 receptors in A-delta neuron
Mechanosensation (3,004 words) [view diff] exact match in snippet view article find links to article
TRPY and TRPC1. Others respond directly to mechanical force, such as TRPN, TRPA1, and TRPV. Others are activated by a second messenger, such as TRPV4. The
GPR3 (1,905 words) [view diff] exact match in snippet view article find links to article
iNOS/eNOS inhibitor. Diphenyleneiodonium chloride (DPI) also functions as a TRPA1 activator and selectively inhibits intracellular reactive oxygen species
Cinnamaldehyde (1,911 words) [view diff] exact match in snippet view article find links to article
vasomotor manifestations of individual and combined stimulation of TRPM8 and TRPA1 using topical L-menthol and trans-cinnamaldehyde in healthy volunteers"
Nociceptor (2,854 words) [view diff] exact match in snippet view article find links to article
same for mechanical stimuli. The same is true for chemical stimuli, since TRPA1 appears to detect both mechanical and chemical changes. Some mechanical
Thrixopelma pruriens (255 words) [view diff] exact match in snippet view article find links to article
Nitabach, Michael N. (2014). "A Tarantula-Venom Peptide Antagonizes the TRPA1 Nociceptor Ion Channel by Binding to the S1–S4 Gating Domain". Current Biology
Hyalinobatrachium fleischmanni (3,135 words) [view diff] exact match in snippet view article find links to article
their sensitivity to near-infrared rays at night. For instance, snakes have TRPA1 in their pit organ which is an ion channel that works as the infrared receptor
Sensory neuron (3,232 words) [view diff] exact match in snippet view article find links to article
(2020-07-08). "Irritant-evoked activation and calcium modulation of the TRPA1 receptor". Nature. 585 (7823): 141–145. Bibcode:2020Natur.585..141Z. doi:10
NADPH oxidase (2,841 words) [view diff] case mismatch in snippet view article find links to article
Lee JH, Park JH, Park SH, et al. (January 2016). Miguel-Aliaga I (ed.). "TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox
Spilanthol (457 words) [view diff] exact match in snippet view article find links to article
an antihypertensive effect that involves CB1 cannabinoid receptors and TRPA1 and TRPV1 channels activation". Planta Medica. doi:10.1055/a-2244-8855.
Baljit S. Khakh (347 words) [view diff] exact match in snippet view article find links to article
Neuroscience. 17(5): pgs. 694-703 Shigetomi E, Tong X... Khakh BS (2012). TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy
Umbellularia (2,027 words) [view diff] exact match in snippet view article find links to article
2014-10-17. Nassini, R.; et al. (2011). "The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system". Brain. 135 (2): 376–90. doi:10
Dimethyl sulfoxide (3,970 words) [view diff] exact match in snippet view article find links to article
taste upon skin contact with DMSO may be due to nonolfactory activation of TRPA1 receptors in trigeminal ganglia. Unlike dimethyl and diallyl disulfides
Wolfgang Bernhard Liedtke (2,221 words) [view diff] exact match in snippet view article find links to article
for TRPV4 in organ-specific inflammation and itch", issued 2017-07-11  "TRPA1 and TRPV4 inhibitors and methods of using the same for organ-specific inflammation
Rhinitis (3,103 words) [view diff] exact match in snippet view article find links to article
Over-expression of transient receptor potential (TRP) ion channels, such as TRPA1 and TRPV1, may be involved in the pathogenesis of non-allergic rhinitis
Garlic (6,702 words) [view diff] exact match in snippet view article find links to article
SunWook; Patapoutian, Ardem (2005). "The Pungency of Garlic: Activation of TRPA1 and TRPV1 in Response to Allicin" (PDF). Current Biology. 15 (10) (published
Pain in invertebrates (9,954 words) [view diff] exact match in snippet view article find links to article
Drosophila to wasabi is mediated by painless, the fly homolog of mammalian TRPA1/ANKTM1". Current Biology. 16 (10): 1034–1040. doi:10.1016/j.cub.2006.04
Scorpion toxin (1,204 words) [view diff] exact match in snippet view article find links to article
"A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain". Cell. 178 (6): 1362–1374.e16. doi:10.1016/j.cell.2019.07.014
U7-ctenitoxin-Pn1a (1,114 words) [view diff] exact match in snippet view article find links to article
Lee, Jong-Seok; Zhang, Youping (August 2009). "Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia". PAIN. 144 (3):
TRPM8 (3,248 words) [view diff] exact match in snippet view article find links to article
vasomotor manifestations of individual and combined stimulation of TRPM8 and TRPA1 using topical L-menthol and trans-cinnamaldehyde in healthy volunteers"
Advanced glycation end-product (3,736 words) [view diff] exact match in snippet view article find links to article
2016). "A Caenorhabditis elegans Model Elucidates a Conserved Role for TRPA1-Nrf Signaling in Reactive Alpha-dicarbonyl Detoxification". Current Biology
Bruce Beutler (12,184 words) [view diff] case mismatch in snippet view article find links to article
Jiamin (May 23, 2018). "Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors". Nature