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searching for The Hallmarks of Cancer 34 found (47 total)

Follicular dendritic cell sarcoma (2,551 words) [view diff] case mismatch in snippet view article find links to article

mitotic spindle, during cell division. This contributes to many of the hallmarks of cancer, including proliferative signaling, growth activation, and replicative

Somatic evolution in cancer (9,909 words) [view diff] case mismatch in snippet view article find links to article

proliferation and survival, such that a mutant cell that acquires one of the hallmarks of cancer (see below), will have a competitive advantage over cells that

Radiobiology evidence for protons and HZE nuclei (2,879 words) [view diff] case mismatch in snippet view article find links to article

including both genetic and epigenetic modifications that are noted as the hallmarks of cancer (Figure 4-8). The goal of this research is to establish a more

Vasculogenic mimicry (3,170 words) [view diff] case mismatch in snippet view article find links to article

to develop and harness nearby vasculature is considered one of the hallmarks of cancer disease development and is thought to be closely linked to tumor

Human hair growth (1,753 words) [view diff] case mismatch in snippet view article find links to article

attacking rapidly dividing cells. Rapid cell replication is one of the hallmarks of cancer; however, hair follicle cells also grow and divide quickly. Consequently

Cyclin B (1,334 words) [view diff] case mismatch in snippet view article find links to article

types of cancer. Hyperplasia (uncontrolled cell growth) is one of the hallmarks of cancer. Because cyclin B is necessary for cells to enter mitosis and therefore

Co-receptor (3,129 words) [view diff] case mismatch in snippet view article find links to article

to reduce signals that instruct the cell to grow and migrate – the hallmarks of cancer. In conjunction, the LRP co-receptor family also mediates binding

Peroxisome proliferator-activated receptor delta (2,093 words) [view diff] exact match in snippet view article find links to article

PMID 17682064. Wagner N, Wagner KD (May 2020). "PPAR Beta/Delta and the Hallmarks of Cancer". Cells. 9 (5): 1133. doi:10.3390/cells9051133. PMC 7291220. PMID 32375405

Endoglin (2,843 words) [view diff] exact match in snippet view article find links to article

inducing apoptosis. However, once the cancer cells have gone through the Hallmarks of Cancer and lost inhibitory growth responses, TGF beta mediates cell invasion

Tyler Jacks (1,105 words) [view diff] exact match in snippet view article find links to article

(7.013) at MIT with Professor Hazel Sive and currently teaches The Hallmarks of Cancer (7.45) at MIT with Professor Matthew Vander Heiden. He served on

Eileen White (489 words) [view diff] case mismatch in snippet view article find links to article

leading to the conclusion that resisting cell death is one of the hallmarks of cancer. This work allowed for the development of Bcl-2 inhibitors as a

Contact inhibition (2,208 words) [view diff] exact match in snippet view article find links to article

PMID 6049107. S2CID 4150783. Hanahan, D.; Weinberg, R. (7 January 2000). "The Hallmarks of Cancer" (PDF). Cell. 100 (1): 57–70. doi:10.1016/s0092-8674(00)81683-9

Hippo signaling pathway (3,130 words) [view diff] case mismatch in snippet view article find links to article

PMID 6029791. S2CID 4256818. Hanahan D, Weinberg RA (January 2000). "The hallmarks of cancer". Cell. 100 (1): 57–70. doi:10.1016/S0092-8674(00)81683-9. PMID 10647931

Cyclin B1 (3,274 words) [view diff] case mismatch in snippet view article find links to article

has been shown to interact with Cdk1, GADD45A and RALBP1. One of the hallmarks of cancer is the lack of regulation in the cell cycle. The role of cyclin

Naked mole-rat (5,402 words) [view diff] case mismatch in snippet view article find links to article

is a double barrier to uncontrolled cell proliferation, one of the hallmarks of cancer. In 2013, scientists reported that the reason naked mole-rats do

USF1 (4,538 words) [view diff] case mismatch in snippet view article find links to article

"Involvement of the pro-oncogenic enzyme fatty acid synthase in the hallmarks of cancer: a promising target in anti-cancer therapies". Oncogenesis. 12

Anaphase lag (1,534 words) [view diff] case mismatch in snippet view article find links to article

cancers as well as debilitating developmental diseases. One of the hallmarks of cancer formation and persistence is genomic instability, referring to

DNA replication (7,287 words) [view diff] case mismatch in snippet view article find links to article

leading to cancer formation. Increased telomerase activity is one of the hallmarks of cancer. Termination requires that the progress of the DNA replication

Chromatin remodeling (5,523 words) [view diff] case mismatch in snippet view article find links to article

PMC 2935570. PMID 20805320. Hanahan D, Weinberg RA (January 2000). "The hallmarks of cancer". Cell. 100 (1): 57–70. doi:10.1016/S0092-8674(00)81683-9. PMID 10647931

Glycolysis (8,694 words) [view diff] exact match in snippet view article find links to article

Schwartz L, Supuran CT, Alfarouk KO (2017). "The Warburg Effect and the Hallmarks of Cancer". Anti-Cancer Agents in Medicinal Chemistry. 17 (2): 164–170. doi:10

Cyclooxygenase-2 inhibitor (4,944 words) [view diff] case mismatch in snippet view article find links to article

C, Kaidi A (March 2009). "The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment". Carcinogenesis

BCL3 (2,553 words) [view diff] case mismatch in snippet view article find links to article

(May 2020). "The role of B-Cell Lymphoma-3 (BCL-3) in enabling the hallmarks of cancer: implications for the treatment of colorectal carcinogenesis".

Aerobic fermentation (3,367 words) [view diff] case mismatch in snippet view article find links to article

in the use of acetic acid bacteria to produce vinegar. One of the hallmarks of cancer is altered metabolism or deregulating cellular energetics. Cancers

Epithelial–mesenchymal transition (6,833 words) [view diff] case mismatch in snippet view article find links to article

PMID 16394028. S2CID 35196500. Hanahan D, Weinberg RA (January 2000). "The hallmarks of cancer". Cell. 100 (1): 57–70. doi:10.1016/s0092-8674(00)81683-9. PMID 10647931

Epigenetic effects of smoking (1,902 words) [view diff] case mismatch in snippet view article find links to article

health and quality of life. Irregular gene expression is one of the hallmarks of cancer, but is also found in a number of diseases and disorders. One of

Chemotherapy (17,496 words) [view diff] case mismatch in snippet view article find links to article

PMID 19104514. S2CID 17934366. Hanahan D, Weinberg RA (January 2000). "The hallmarks of cancer". Cell. 100 (1): 57–70. doi:10.1016/S0092-8674(00)81683-9. PMID 10647931

Transforming growth factor beta (8,485 words) [view diff] case mismatch in snippet view article find links to article

PMC 3144160. PMID 21436399. Hanahan D, Weinberg RA (January 2000). "The hallmarks of cancer". Cell. 100 (1): 57–70. doi:10.1016/S0092-8674(00)81683-9. PMID 10647931

Warren Jackson Pledger (1,467 words) [view diff] case mismatch in snippet view article find links to article

transduction pathway inhibition on CRC tumor cell survival, and the hallmarks of cancer during the evolution of tumor progression seeking to find new therapeutic

Human papillomavirus infection (16,008 words) [view diff] exact match in snippet view article find links to article

S2CID 71143679. Hanahan, Douglas; Weinberg, Robert A. (7 January 2000). "The Hallmarks of Cancer". Cell. 100 (1): 57–70. doi:10.1016/S0092-8674(00)81683-9. ISSN 0092-8674

Tumor microenvironment (6,813 words) [view diff] case mismatch in snippet view article find links to article

vasculature, sustained angiogenesis is therefore considered one of the hallmarks of cancer. In later stages of tumor progression endothelial cells can differentiate

BNIP3 (2,672 words) [view diff] case mismatch in snippet view article find links to article

"Guidelines for the selection of functional assays to evaluate the hallmarks of cancer". Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1866

Breast cancer classification (9,503 words) [view diff] case mismatch in snippet view article find links to article

the pathologist sees in 10x high power microscope field. One of the hallmarks of cancer is that cells divide uncontrollably. The more cells that are dividing

Mouse models of breast cancer metastasis (5,955 words) [view diff] case mismatch in snippet view article find links to article

Site-specific recombinase technology Hanahan, D.; Weinberg, R. (2000). "The hallmarks of cancer". Cell. 100 (1): 57–70. doi:10.1016/S0092-8674(00)81683-9. PMID 10647931

Physical oncology (6,734 words) [view diff] case mismatch in snippet view article find links to article

Valerie M. (2014-12-01). "The extracellular matrix modulates the hallmarks of cancer". EMBO Reports. 15 (12): 1243–1253. doi:10.15252/embr.201439246