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Longer titles found: Transgene (company) (view), Transgenerational (view), Transgenerational design (view), Transgenerational epigenetic inheritance (view), Transgenerational epigenetic inheritance in plants (view), Transgenerational trauma (view)

searching for Transgene 162 found (291 total)

alternate case: transgene

Reporter gene (1,980 words) [view diff] no match in snippet view article find links to article

In molecular biology, a reporter gene (often simply reporter) is a gene that researchers attach to a regulatory sequence of another gene of interest in

Episome (512 words) [view diff] exact match in snippet view article find links to article

expression of the carried transgene. Among these features is the number of CpG sites which contribute to epigenetic silencing of the transgene carried by the episome

Brigid Hogan (1,219 words) [view diff] exact match in snippet view article find links to article

Technologies Prize in 2008 for "outstanding contributions to the field of transgene technologies". She delivered a 2011 Martin Rodbell Lecture, hosted by

Polly and Molly (888 words) [view diff] exact match in snippet view article find links to article

this new genetic information, the pattern of expression of the injected transgene's protein due to the random integration is very variable. As the aim of

Daphrose Gahakwa (356 words) [view diff] exact match in snippet view article find links to article

in England. Her PhD was entitled "Molecular and Biochemical Studies of Transgene expression in Rice and Maize". She was appointed Minister of Education

Désiré Collen (5,240 words) [view diff] exact match in snippet view article find links to article

Center for Molecular and Vascular Biology) and the VIB Department for Transgene Technology and Gene Therapy (now VIB-KU Leuven Center for Cancer Biology)

Richard Lathe (1,465 words) [view diff] exact match in snippet view article find links to article

University of Pushchino. He was assistant director at the biotech company Transgene in Strasbourg, a principal scientist at ABRO, Edinburgh, and Co-Director

Poliovirus (5,732 words) [view diff] exact match in snippet view article find links to article

mice, the transgene encoding the human PVR was incorporated into mouse chromosome 4. These mice express the highest levels of the transgene and the highest

Infected cell protein 47 (239 words) [view diff] exact match in snippet view article find links to article

simplex virus ICP47 and human cytomegalovirus US11 prevents recognition of transgene products by CD8(+) cytotoxic T lymphocytes". Journal of Virology. 74 (10):

DNA adenine methylase (1,844 words) [view diff] exact match in snippet view article find links to article

Dam is fused to a DNA-binding protein of interest and expressed as a transgene in a genetically tractable model organism to identify protein binding

Jean-Pierre Lecocq (1,736 words) [view diff] no match in snippet view article find links to article

In 1984, Lecocq became vice president and in 1990 President of Transgène. After Transgène was acquired in 1991 by the Mérieux group, Lecocq also became

Expression cassette (370 words) [view diff] exact match in snippet view article find links to article

et al. (January 2015). "Viral Expression Cassette Elements to Enhance Transgene Target Specificity and Expression in Gene Therapy". Discov Med. 19 (102):

Darling 58 (1,518 words) [view diff] exact match in snippet view article find links to article

efficient compared to the "always-on" CAMV promoter and thereby have greater transgene stability over successive generations compared with the Darling 58 variant

HBsAg (415 words) [view diff] exact match in snippet view article find links to article

Today, these antigen-proteins can be genetically manufactured (e.g. transgene E. coli) to produce material for a simple antigen test, which detects

UNC (biology) (2,673 words) [view diff] exact match in snippet view article

to the source of UNC-6 production. Methods such as antibody staining, transgene expression and microarray analysis have confirmed that UNC-5 is expressed

Arctic Apples (996 words) [view diff] exact match in snippet view article find links to article

aspects of the apple. The RNAi process is accomplished through the use of a transgene that uses gene sequences that control PPO production. Promoter and terminator

UNC-5 (2,577 words) [view diff] exact match in snippet view article find links to article

to the source of UNC-6 production. Methods such as antibody staining, transgene expression and microarray analysis have confirmed that UNC-5 is expressed

2Blades (1,379 words) [view diff] exact match in snippet view article find links to article

Reuber, T.; Steffenson, Brian J.; Ayliffe, Michael (2021-01-04). "A five-transgene cassette confers broad-spectrum resistance to a fungal rust pathogen in

Mirus Bio (582 words) [view diff] exact match in snippet view article find links to article

development of a non-viral vector providing sustained liver-specific transgene expression for more than one year. In 2008 the Therapeutics Division was

Exon (1,517 words) [view diff] exact match in snippet view article find links to article

(January 2017). "A 5' Noncoding Exon Containing Engineered Intron Enhances Transgene Expression from Recombinant AAV Vectors in vivo". Human Gene Therapy.

GAL4/UAS system (1,800 words) [view diff] exact match in snippet view article find links to article

interfere with other processes in the cell. For example, GAL4/UAS-regulated transgenes in Drosophila have been used to alter glial expression to produce arrhythmic

EIF4G2 (1,114 words) [view diff] exact match in snippet view article find links to article

mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme". Genes Dev. 11 (3): 321–33

Jeannie T. Lee (1,421 words) [view diff] exact match in snippet view article find links to article

centre. JT Lee, LS Davidow, D Warshawsky. Nature Genetics, 1999 A 450 kb transgene displays properties of the mammalian X-inactivation center. JT Lee, WM

Cadherin-2 (3,399 words) [view diff] exact match in snippet view article find links to article

adult hearts via a cardiac-specific tamoxifen-inducible Cre N-cadherin transgene showed disrupted assembly of intercalated discs, dilated cardiomyopathy

HBP1 (972 words) [view diff] exact match in snippet view article find links to article

mobility group box transcription factor 1 affects thymocyte development and transgene variegation". J. Immunol. 175 (8): 5203–12. doi:10.4049/jimmunol.175.8

Ling Meng (863 words) [view diff] exact match in snippet view article find links to article

Lemaux, PG Meng L (2006) Nature of Stress and Type of Transgene Locus Influences Tendency of Transgenes to Silence in Barley, 15–28. In Plant Mol Biol. S

Edible vaccine (2,291 words) [view diff] exact match in snippet view article find links to article

The transgene can be expressed either through a stable transformation system or through transient transformation system based on where the transgene has

CAC Small (481 words) [view diff] exact match in snippet view article find links to article

Synergie Technicolor Tikehau Capital TOUAX SCA Tour Eiffel (Société de la) Transgene Union Financière de France Banque Union Technologies Informatique Group

Genome editing (9,341 words) [view diff] exact match in snippet view article find links to article

with stem cells Transgenic animals Endogenous gene labeling Targeted transgene addition The combination of recent discoveries in genetic engineering

Danon disease (1,111 words) [view diff] exact match in snippet view article find links to article

Containing the Human Lysosome-Associated Membrane Protein 2 Isoform B (LAMP2B) Transgene (RP-A501; AAV9.LAMP2B) in Male Patients with DD". Clinical Trials. 24

Parthenocarpy (977 words) [view diff] exact match in snippet view article find links to article

Pandolfini T, Rotino GL, Camerini S, Defez R, Spena A (2002). "Optimisation of transgene action at the post-transcriptional level: high quality parthenocarpic

CREB in cognition (1,689 words) [view diff] exact match in snippet view article find links to article

strategy. In this strategy, a fragment of the CREB gene was expressed from a transgene in mice. The resulting transgenic protein was engineered to interfere

CAG promoter (444 words) [view diff] exact match in snippet view article find links to article

level of recombinant proteins, as well as increases the expression of transgenes under low temperature conditions. Okabe M, Ikawa M, Kominami K, Nakanishi

Spatiotemporal gene expression (1,411 words) [view diff] exact match in snippet view article find links to article

spatiotemporally. Recently light based control has been shown at DNA level using transgene based system or caged triplex forming oligos Cohen, DJ; Morfino, RC; Maharbiz

Sweet potato feathery mottle virus (2,446 words) [view diff] exact match in snippet view article find links to article

immunity to SPFMV in susceptible plants. One such method is the creation of transgene plants using proteins such as cysteine proteinase inhibitors, which would

Northern blot (2,120 words) [view diff] exact match in snippet view article find links to article

mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme". Genes Dev. 11 (3): 321–333

Real-time polymerase chain reaction (5,338 words) [view diff] exact match in snippet view article find links to article

usually less sensitive. Specific primers are used that amplify not the transgene but the promoter, terminator or even intermediate sequences used during

ANDi (429 words) [view diff] exact match in snippet view article find links to article

proceeded. In these three monkey births, only one infant, ANDi, carried the transgene. Research team leader Gerald Schatten said the technique that created

Overlap extension polymerase chain reaction (1,051 words) [view diff] exact match in snippet view article find links to article

M. (2020-01-01). "Optimization of overlap extension PCR for efficient transgene construction". MethodsX. 7: 100759. doi:10.1016/j.mex.2019.12.001. ISSN 2215-0161

ANDi (429 words) [view diff] exact match in snippet view article find links to article

proceeded. In these three monkey births, only one infant, ANDi, carried the transgene. Research team leader Gerald Schatten said the technique that created

PAX2 (1,868 words) [view diff] exact match in snippet view article find links to article

expressed in a narrow ring centered at the MHB during somitogenesis. Transgene expression of the mid-hindbrain and developing kidney is directed by Pax2

Callus (cell biology) (2,008 words) [view diff] exact match in snippet view article

transgenics researchers to obtain whole plants which have a copy of the transgene in every cell. Regeneration of a whole plant that has some genetically

Isogenic human disease models (2,046 words) [view diff] exact match in snippet view article find links to article

001. Hirata R, Chamberlain J, Dong R, Russell DW (July 2002). "Targeted transgene insertion into human chromosomes by adeno-associated virus vectors". Nat

Richard Smeyne (606 words) [view diff] exact match in snippet view article find links to article

were one of the first to generate a transgenic mouse that expressed the transgene under the control of its cognate promoter. In 1992, following his postdoctoral

Green fluorescent protein (7,456 words) [view diff] exact match in snippet view article find links to article

(2002-09-01). "Progression of geminivirus-induced transgene silencing is associated with transgene methylation". New Phytologist. 155 (3): 461–468. doi:10

Dependoparvovirus (843 words) [view diff] exact match in snippet view article find links to article

System Expands Adeno-associated Viral Vector Packaging Capacity in a Transgene- Independent manner" (PDF). Molecular Therapy. 16 (1): 124–130. doi:10

Margaret A. Liu (1,472 words) [view diff] no match in snippet view article find links to article

vaccine research and gene therapy at Chiron Corporation, a Vice-Chairman at Transgène, an independent director of Ipsen, the president of the International

Plasmodium molecular tools (504 words) [view diff] exact match in snippet view article find links to article

Koning-Ward, TF; Soldati, D; Crabb, BS (2005). "Tetracycline analogue-regulated transgene expression in Plasmodium falciparum blood stages using Toxoplasma gondii

BioArt (3,938 words) [view diff] exact match in snippet view article find links to article

2023-09-24. Eduardo Kac (1998), "Transgene Kunst", Leonardo Electronic Almanac, vol. 6, no. 11 Eduardo Kac (1999). "Transgene Kunst". Retrieved 2021-08-05

Dally (gene) (825 words) [view diff] exact match in snippet view article

the cell surface. Moreover, ectopic expression of dally+ from hs-dally+ transgene, stimulates Wg signaling. Thus, naked larval cuticle loss is recuperated

CREB (2,243 words) [view diff] exact match in snippet view article find links to article

Zhou H, Quinn W, Tully T (1994). "Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila". Cell. 79 (1): 49–58

20-Hydroxyecdysone (1,186 words) [view diff] exact match in snippet view article find links to article

bioavailability when taken orally, so it is useful for determining whether the transgene has been taken up effectively. Ecdybase, The Ecdysone Handbook - a free

Oncolytic adenovirus (4,209 words) [view diff] exact match in snippet view article find links to article

its replication in the tumor cells. Arming with Transgenes To enhance the efficacy, therapeutic transgenes are integrated into oncolytic adenovirus stimulation

Umeå University (2,723 words) [view diff] exact match in snippet view article find links to article

Plant Science Center (UPSC) Umeå School of Sports Sciences (USSS) Umeå Transgene Core Facility (UTCF) Vaartoe – Centre for Sami Research (Cesam) Practically

OPN1LW (2,372 words) [view diff] exact match in snippet view article find links to article

Simon MI, Bogenmann E (1994). "The human blue opsin promoter directs transgene expression in short-wave cones and bipolar cells in the mouse retina"

Gene knock-in (1,568 words) [view diff] exact match in snippet view article find links to article

used for conditional gene knock-ins; making combinations of reporter and transgenes in the same locus problematic. The biggest disadvantage of using gene

Phillip Allen Sharp (2,294 words) [view diff] exact match in snippet view article find links to article

Sinskey J.L.; Sharp P.A. (March 15, 2005). "Transcriptional Silencing of a Transgene by RNAi in the Soma of C. elegans". Genes Dev. 19 (6): 683–96. doi:10

Area postrema (3,006 words) [view diff] exact match in snippet view article find links to article

Matsumura, K.; Ganten, D.; Ferrario, C. M. (1996). "Role of area postrema in transgene hypertension". Hypertension. 27 (3 Pt 2): 591–597. doi:10.1161/01.HYP

ALOX15 (5,728 words) [view diff] exact match in snippet view article find links to article

decline as the cancers progress. These results, as well as a 15-LOX-1 transgene study on colon cancer in mice suggests but do not prove that 15-LOX-1

Molecular breeding (1,105 words) [view diff] exact match in snippet view article find links to article

crossing an F1 with its parents to transfer a limited number of loci (e.g. transgene, disease resistance loci, etc.) from one genetic background to another

Insulator (genetics) (2,064 words) [view diff] exact match in snippet view article

genetic insulator in vivo as it has both enhancer-blocking activity and transgene barrier activities. CTCF was first characterized for its role in regulating

Enamelin (1,622 words) [view diff] exact match in snippet view article find links to article

structures (often, horizontal grooves) on the surface of enamel, and with high transgene expression, the enamel layer is almost lost. Ameloblastin Amelogenin Amelogenesis

Plasmid (5,331 words) [view diff] exact match in snippet view article find links to article

Coutelle C, Miller AD, Harbottle RP (December 2008). "Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment

Cre-Lox recombination (5,058 words) [view diff] exact match in snippet view article find links to article

the fluorescent transgene reporter (e.g. a CAG promoter) and a loxP flanked stop cassette, ensuring the expression of the transgene is Cre-recombinase

DNA Plant Technology (1,165 words) [view diff] exact match in snippet view article find links to article

regulation and crop manipulation. Key experiments in the control of plant transgene expression were performed by Jorgensen after he joined DNA Plant Technology

Marnie Blewitt (652 words) [view diff] exact match in snippet view article find links to article

Cox TX and Whitelaw E. (2008) A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development. Genome

Marnie Blewitt (652 words) [view diff] exact match in snippet view article find links to article

Cox TX and Whitelaw E. (2008) A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development. Genome

RNA-induced transcriptional silencing (986 words) [view diff] exact match in snippet view article find links to article

(2006). "The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells"

Jean Bennett (2,340 words) [view diff] exact match in snippet view article find links to article

Chirmule, N.; Gupta, A. R.; Huang, Y.; Gao, G. P. (1999-08-17). "Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated

DAZL (1,280 words) [view diff] exact match in snippet view article find links to article

SM, Ross A, McGill NI, Saunders PT, Cooke HJ (Jul 1999). "A human DAZ transgene confers partial rescue of the mouse Dazl null phenotype". Proceedings

Red flour beetle (2,385 words) [view diff] exact match in snippet view article find links to article

Schinko, J. Averof, M. 2015. Efficient CRISPR-mediated gene targeting and transgene replacement in the beetle Tribolium castaneum. Development. Good, M.E

Protein c-Fos (3,981 words) [view diff] exact match in snippet view article find links to article

proteins does not induce any malignant tumors. Activation of the c-Fos transgene in mice results in overexpression of cyclin D1, A and E in osteoblasts

David Baulcombe (1,953 words) [view diff] exact match in snippet view article find links to article

Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus". Cell. 101 (5): 543–553. doi:10.1016/S0092-8674(00)80864-8

Intracellular delivery (8,780 words) [view diff] exact match in snippet view article find links to article

efficiency (by optimizing the transgene cassette), vector tropism (using capsid engineering) and the ability of the capsid and transgene to avoid the host immune

Adeno-associated virus (8,636 words) [view diff] exact match in snippet view article find links to article

are more receptive to AAV treatment and demonstrate higher levels of transgene expression Due to previous natural infection, many people have preexisting

Idah Sithole-Niang (754 words) [view diff] exact match in snippet view article find links to article

Expressing HC-Pro Show Enhanced Virus Sensitivity While Silencing of the Transgene Results in Resistance". Virus Genes. 25 (1): 45–57. doi:10.1023/a:1020170024713

Michelson Prize and Grants in Reproductive Biology (407 words) [view diff] exact match in snippet view article find links to article

cat using viral-vectored delivery of a feline anti-Müllerian hormone transgene". Nature Communications. 14 (1): 3140. doi:10.1038/s41467-023-38721-0

Riboswitch (3,887 words) [view diff] exact match in snippet view article find links to article

Gantner F, Kreuz S (October 2015). "Riboswitch-mediated Attenuation of Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293

Transfer DNA (1,837 words) [view diff] exact match in snippet view article find links to article

B, Wang K, Gelvin SB (March 2010). "Generation of backbone-free, low transgene copy plants by launching T-DNA from the Agrobacterium chromosome". Plant

Feline immunodeficiency virus (4,960 words) [view diff] exact match in snippet view article find links to article

the chromosome of the host cell, where it can generate long-term stable transgene expression. Furthermore, the vectors can be used on dividing and non-dividing

Glyoxylate cycle (2,510 words) [view diff] exact match in snippet view article find links to article

1155/2015/895453. PMC 4306415. PMID 25649791. Ward KA (March 2000). "Transgene-mediated modifications to animal biochemistry". Trends in Biotechnology

Glossary of cellular and molecular biology (0–L) (24,442 words) [view diff] exact match in snippet view article

attached X. conditional expression The controlled, inducible expression of a transgene, either in vitro or in vivo. confluence In cell culture, a measure of

Laura Manuelidis (3,860 words) [view diff] exact match in snippet view article find links to article

diseases and tumor progression. Finally, the insertion of a huge 11 megabase transgene of the globin exon (lacking introns) was recognized by cells, and silenced

X-linked severe combined immunodeficiency (4,341 words) [view diff] exact match in snippet view article find links to article

2006). "Gene therapy: Is IL2RG oncogenic in T-cell development?: X-SCID transgene leukaemogenicity (reply)". Nature. 443 (7109): E6–E7. Bibcode:2006Natur

Eric Kandel (4,166 words) [view diff] exact match in snippet view article find links to article

impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene". PNAS. 94 (9): 4761–4765. Bibcode:1997PNAS...94.4761K. doi:10.1073/pnas

Fragile X syndrome (6,790 words) [view diff] exact match in snippet view article find links to article

(June 2008). "Social behavior in Fmr1 knockout mice carrying a human FMR1 transgene". Behavioral Neuroscience. 122 (3): 710–715. doi:10.1037/0735-7044.122

Listeria monocytogenes (4,780 words) [view diff] exact match in snippet view article find links to article

Chakraborty T, et al. (2002). "Listeria monocytogenes mediated CFTR transgene transfer to mammalian cells". The Journal of Gene Medicine. 4 (6): 655–67

Drosomycin (1,251 words) [view diff] exact match in snippet view article find links to article

Uttenweiler-Joseph S, Michaut L, et al. (August 1998). "A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on

Herpes simplex virus (7,285 words) [view diff] exact match in snippet view article find links to article

simplex virus ICP47 and human cytomegalovirus US11 prevents recognition of transgene products by CD8(+) cytotoxic T lymphocytes". Journal of Virology. 74 (10):

Steven J. Burakoff (915 words) [view diff] exact match in snippet view article find links to article

SJ, Mishra B. PLoS Computational Biology, 2007 PMID 17319736 A CD8/Lck transgene is able to drive thymocyte differentiation. Fragoso RC, Pyarajan S, Irie

BacMam (1,671 words) [view diff] exact match in snippet view article find links to article

Nallasivam; Wang, Shu (2007). "Baculoviral Vector-Mediated Transient and Stable Transgene Expression in Human Embryonic Stem Cells". Stem Cells. 25 (4): 1055–1061

Anterograde tracing (1,885 words) [view diff] exact match in snippet view article find links to article

Saper CB (May 1998). "Recombinant adeno-associated virus vector: use for transgene expression and anterograde tract tracing in the CNS". Brain Research.

Programmed cell death (6,757 words) [view diff] exact match in snippet view article find links to article

cerebellar Purkinje cell numbers in mice overexpressing a human bcl-2 transgene". Journal of Computational Neurology. 374 (3): 332–341. doi:10

Narcolepsy (8,196 words) [view diff] exact match in snippet view article find links to article

technology exists in early form such as experiments in using the prepro-orexin transgene via gene editing restored normal function in mice models by making other

Nanobiotechnology (5,086 words) [view diff] exact match in snippet view article find links to article

Michael G.; Maeng, Lisa Y.; Widge, Alik S.; Anikeeva, Polina (April 2020). "Transgene-free remote magnetothermal regulation of adrenal hormones". Science Advances

Chestnut blight (4,497 words) [view diff] exact match in snippet view article find links to article

Powell, William A. (2013-03-31). "A threshold level of oxalate oxidase transgene expression reduces Cryphonectria parasitica-induced necrosis in a transgenic

Transcription factor (8,019 words) [view diff] exact match in snippet view article find links to article

component for all vectors. Used to drive transcription of the vector's transgene promoter sequences) adjacent to regulated genes. DNA sequences that bind

MARCM (1,436 words) [view diff] exact match in snippet view article find links to article

L; Luo L. (2010-04-30). "The Q system: a repressible binary system for transgene expression, lineage tracing, and mosaic analysis". Cell. 141 (3): 536–48

Norman Maclean (biologist) (1,861 words) [view diff] exact match in snippet view article

exploitation of transgenes in fish. Mutat Res. 399(2): 255–66 Iyengar, A., Muller, F. and Maclean, N. (1996) Regulation and expression of transgenes in fish –

VPS26A (1,458 words) [view diff] exact match in snippet view article find links to article

evolutionarily conserved gene disrupted by the murine H beta 58 embryonic lethal transgene insertion". Development. 115 (1): 277–88. doi:10.1242/dev.115.1.277. PMID 1638986

Sperm-mediated gene transfer (1,053 words) [view diff] exact match in snippet view article find links to article

but only about 25 percent of these demonstrated a transmission of the transgenes beyond the F0 generation.4 This transmission is required in order to claim

Dravet syndrome (4,117 words) [view diff] exact match in snippet view article find links to article

(AAV9) SCN1A gene regulation therapy. It has been designed to target transgene expression to GABAergic inhibitory neurons and reduce off-target expression

Cassava brown streak virus (1,725 words) [view diff] exact match in snippet view article find links to article

which serves multiple functions in the CBSV life cycle, was used as the transgene of interest. Three distinct RNAi constructs were designed to target the

Zinc-finger nuclease (4,657 words) [view diff] exact match in snippet view article find links to article

Rubin-Wilson B, Gregory PD, Urnov FD, Petolino JF (2008). "Targeted transgene integration in plant cells using designed zinc finger nucleases". Plant

Gary K. Michelson (2,812 words) [view diff] exact match in snippet view article find links to article

cat using viral-vectored delivery of a feline anti-Müllerian hormone transgene". Nature Communications. 14 (1): 3140. Bibcode:2023NatCo..14.3140V. doi:10

Zhuo-Hua Pan (1,150 words) [view diff] exact match in snippet view article find links to article

Ganjawala, H. T., and Pan, Z.-H. Cre-mediated recombination efficiency and transgene expression patterns of three retinal bipolar cell-expressing Cre transgenic

Cytokine delivery systems (3,386 words) [view diff] exact match in snippet view article find links to article

off-target transgene expression seen in clinical trials. Small volumes of intratumoral injection of adenoviruses were shown to cause significant transgene expression

Avesthagen (1,742 words) [view diff] exact match in snippet view article find links to article

development of novel seed research, application of molecular markers and transgene based technologies to develop more productive food, feed, fuel and fiber

Viral neuronal tracing (2,593 words) [view diff] exact match in snippet view article find links to article

Saper (May 18, 1998). "Recombinant adeno-associated virus vector: use for transgene expression and anterograde tract tracing in the CNS". Brain Res. 793 (1–2):

Plastid evolution (1,294 words) [view diff] exact match in snippet view article find links to article

Stephanie; Karcher, Daniel; Bock, Ralph (24 April 2007). "Determining the transgene containment level provided by chloroplast transformation". Proceedings

Amniotic stem cells (3,054 words) [view diff] exact match in snippet view article find links to article

confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach". Mol Ther. 20 (10): 1953–1967. doi:10.1038/mt.2012.117

Gene silencing (5,608 words) [view diff] exact match in snippet view article find links to article

Imprinting Paramutation Transposon silencing (or Histone Modifications) Transgene silencing Position effect RNA-directed DNA methylation RNA interference

Fan Wang (neuroscientist) (1,032 words) [view diff] exact match in snippet view article

specifically infect activated cells and drive stable expression of a desired transgene. This technique has been used to identify circuits involved in social

Bacillus thuringiensis (7,829 words) [view diff] exact match in snippet view article find links to article

Freeling M (April 2002). "Biodiversity (Communications arising): maize transgene results in Mexico are artefacts". Nature. 416 (6881): 601–2, discussion

PTPRK (4,376 words) [view diff] exact match in snippet view article find links to article

transmembrane domain of the type I transmembrane protein CD4. If the transgene was incorporated into a gene with a signal sequence, β-gal activity would

Introduction to evolution (9,137 words) [view diff] exact match in snippet view article find links to article

London: BBC. Retrieved 2007-12-14. Hall, Hardy (November 7, 2005). "Transgene Escape: Are Traditional Corn Varieties In Mexico Threatened by Transgenic

Monoallelic gene expression (1,444 words) [view diff] exact match in snippet view article find links to article

Hadjantonakis AK, Cox LL, Tam PP, Nagy A (March 2001). "An X-linked GFP transgene reveals unexpected paternal X-chromosome activity in trophoblastic giant

Ganglion mother cell (1,795 words) [view diff] exact match in snippet view article find links to article

traced through a lineage using methods such as green fluorescent protein transgene expression in order to investigate mechanisms of cellular diversity. A

Hans Rudolf Herren (2,073 words) [view diff] exact match in snippet view article find links to article

flow assessment through evaluation of pollinator foraging range suggests transgene escape distances. PNAS: 2008;105(36):13456-6 Herren, H. & Baumgärtner

Methylated-DNA-protein-cysteine methyltransferase (3,856 words) [view diff] exact match in snippet view article find links to article

gene therapy efficiency. By using a two component vector consisting of a transgene of interest and MGMT, in vivo drug selection can be utilized to select

Horizontal gene transfer (11,833 words) [view diff] exact match in snippet view article find links to article

Burkhardt NY, Blazar BR, Hackett PB, Meyer JM, Munderloh UG (October 2008). "Transgene expression and silencing in a tick cell line: A model system for functional

Ingo Potrykus (1,361 words) [view diff] exact match in snippet view article find links to article

Potrykus I, Hohn T, Futterer J (2002) Tissue-specific silencing of a transgene in rice. PNAS 99:10881-10886. Lucca P, Hurrell R, Potrykus I (2002) Fighting

Marie-Paule Kieny (1,285 words) [view diff] exact match in snippet view article find links to article

universal health care. After completing her PhD, Kieny took up a position at Transgene SA, Strasbourg, as assistant scientific director under scientific director

Amniotic epithelial cell (1,766 words) [view diff] exact match in snippet view article find links to article

et al. (January 31, 2000). "Human Amniotic Epithelial cells are promising transgene carriers for Allogenic Cell transplantation" (PDF). Journal of Human Genetics

Cellular senescence (6,395 words) [view diff] exact match in snippet view article find links to article

ultimately extend life. In the 2011 Nature paper by Baker et al. a novel transgene, INK-ATTAC, was used to inducibly eliminate p16 INK4A-positive senescent

Site-specific recombinase technology (3,200 words) [view diff] exact match in snippet view article find links to article

has to be invested in the design of routes applied for the delivery of transgenes. Although for biotechnological purposes random integration is still common

Cancer immunotherapy (9,943 words) [view diff] exact match in snippet view article find links to article

Engineered Vaccinia Viruses As Agents for Cancer Treatment, Imaging, and Transgene Delivery". Frontiers in Oncology. 7: 96. doi:10.3389/fonc.2017.00096.

Jonathan Gressel (2,574 words) [view diff] exact match in snippet view article find links to article

long-term control of weedy rice while mitigating herbicide resistance transgene flow, and its potential use for other crops with related weeds". Pest

Vectors in gene therapy (4,918 words) [view diff] exact match in snippet view article find links to article

construct". The transfer construct carries the gene to be transduced or "transgene". The transfer construct also carries the sequences which are necessary

Valoctocogene roxaparvovec (1,233 words) [view diff] exact match in snippet view article find links to article

Huang M, Srimani J, Mackenzie D, et al. (November 2020). "Activity of transgene-produced B-domain-deleted factor VIII in human plasma following AAV5 gene

Intracerebroventricular injection (2,827 words) [view diff] exact match in snippet view article find links to article

injection of AAV vectors is successful for having a lasting expression of the transgene. Primary malignant brain tumors (PMBT) and brain metastases have a high

PQBP1 (3,160 words) [view diff] exact match in snippet view article find links to article

they showed cognitive impairment and microcephaly. The KD mice possess a transgene expressing 498 bp double-strand RNA that is endogenously cleaved to siRNA

Synthetic biology (18,308 words) [view diff] exact match in snippet view article find links to article

"traditional genetic engineering", which involves introducing a single transgene into the intended organism. Bioengineers adapted synthetic biology to

Aliasger K. Salem (838 words) [view diff] exact match in snippet view article find links to article

Technology | Science News Nature view "Silicalite nanoparticles promote transgene expression - nanotechweb.org". Archived from the original on 2015-02-24

Isabelle M. Germano (1,583 words) [view diff] exact match in snippet view article find links to article

l, Qader Z, Binello E, Uzzaman M. Embryonic stem cell (ESC) –mediated transgene delivery induces growth suppression, apoptosis, radiosensitization, and

CRISPR activation (2,672 words) [view diff] exact match in snippet view article find links to article

create phenotypes in plants that are similar to those observed when a transgene is inserted for overexpression. Researchers have used multiple guide RNAs

Polina Anikeeva (2,030 words) [view diff] exact match in snippet view article find links to article

Christiansen, Michael G.; Maeng, Lisa Y.; Widge, Alik S. (April 2020). "Transgene-free remote magnetothermal regulation of adrenal hormones". Science Advances

Orthogonal ligand-protein pair (1,105 words) [view diff] exact match in snippet view article find links to article

Zhao, H (July 2005). "Creating new specific ligand-receptor pairs for transgene regulation". Trends in Biotechnology. 23 (7): 333–335. doi:10.1016/j.tibtech

Biocontainment of genetically modified organisms (4,699 words) [view diff] exact match in snippet view article find links to article

inherited, the transgenes are not spread by pollen thus achieving biological containment. In other words, the cell nucleus contains no transgenes, and the pollen

Murine respirovirus (31,229 words) [view diff] exact match in snippet view article find links to article

variants of genetically engineered constructs, including vectors for transgene delivery. Creation of SeV genetic constructs is easier compared to other

Cancer stem cell (10,288 words) [view diff] exact match in snippet view article find links to article

Hindawi. Haupt Y, Bath ML, Harris AW, Adams JM (November 1993). "bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis". Oncogene

Michel Sadelain (2,399 words) [view diff] exact match in snippet view article find links to article

gene transfer in hematopoietic stem cells and T cells, the regulation of transgene expression, the biology of chimeric antigen receptors, and therapeutic

Non-surgical fertility control for dogs and cats (1,965 words) [view diff] exact match in snippet view article find links to article

Pepin, David (July 2018). "Gene therapy using AAV9-delivery of an MIS transgene inhibits estrus in female cats" (PDF). Li, Juan; et al. (2015). "Vectored

Network motif (10,178 words) [view diff] exact match in snippet view article find links to article

Shimoga V, White J, Li Y, Sontag E, Bleris L (2013). "Synthetic mammalian transgene negative autoregulation". Mol. Syst. Biol. 9: 670. doi:10.1038/msb.2013

Fidanacogene elaparvovec (752 words) [view diff] exact match in snippet view article find links to article

Hemophilia B - 1 Year Follow up and Impact of Baseline Characteristics on Transgene-Derived Factor IX Activity and Persistence". Blood. 130: 601. doi:10.1182/blood

DISC1 (4,723 words) [view diff] exact match in snippet view article find links to article

isoforms have been identified at the RNA level, including a TSNAX-DISC1 transgene splice variant, and at the protein level. Of the isolated RNA isomers

Douglas G. McMahon (2,221 words) [view diff] exact match in snippet view article find links to article

state and the firing rate of SCN neurons. Thus, this circadian reporter transgene depicts gene expression dynamics of biological clock neurons, giving a

Perlecan (11,011 words) [view diff] exact match in snippet view article find links to article

membranes made by endothelial, epithelial or muscle cells. The perlecan transgene in the perlecan null mouse eliminated lethality and restored long bone

Mendocino County GMO Ban (3,212 words) [view diff] exact match in snippet view article find links to article

produced from a range of recombinant DNA technologies, which introduce a transgene into the genome of a host cell. The most widely practiced method involves

Eosinophilic myocarditis (3,618 words) [view diff] exact match in snippet view article find links to article

made hypereosinophilic by the forced overexpression of an interleukin-5 transgene (interleukin 5 stimulates eosinophil proliferation, activation, and migration)

Blebbistatin (3,042 words) [view diff] exact match in snippet view article find links to article

life of adult mouse cardiac myocytes and allows efficient and stable transgene expression". American Journal of Physiology. Heart and Circulatory Physiology

FAM208b (2,213 words) [view diff] exact match in snippet view article find links to article

FAM208a. FAM208a is also known as "retinoblastoma-associated protein 140", "Transgene Activation Suppression Protein" (TASOR), "CTCL Tumor Antigen", and "chromosome

Bert Poolman (2,335 words) [view diff] exact match in snippet view article find links to article

and Biotechnology Institute. In 1993 Poolman has done a sabbatical at Transgene SA, Strasbourg (France). Thanks to a Fulbright fellowship, he was visiting

Steven M. Reppert (4,234 words) [view diff] exact match in snippet view article find links to article

showed that both monarch CRY1 and CRY2 proteins, when expressed as a transgene in CRY-deficient flies, successfully restore light-dependent magnetosensitivity

Timeline of biotechnology (24,276 words) [view diff] exact match in snippet view article find links to article

G.; Maeng, Lisa Y.; Widge, Alik S.; Anikeeva, Polina (1 April 2020). "Transgene-free remote magnetothermal regulation of adrenal hormones". Science Advances

Sandra J. F. Degen (2,369 words) [view diff] exact match in snippet view article find links to article

Coleman MJ, Witte DP, Degen SJ. Rescue of prothrombin-deficiency by transgene expression in mice. Thrombosis and Haemostasis. 88: 984–91. PMID 12529749

Shapiro–Senapathy algorithm (6,804 words) [view diff] exact match in snippet view article find links to article

ubiquitin 2 gene from Porteresia coarctata makes efficient promoters for transgene expression in monocots and dicots". Plant Cell Reports. 32 (8): 1199–1210

Focused ultrasound for intracranial drug delivery (4,384 words) [view diff] exact match in snippet view article find links to article

Elizabeth M.; Hynynen, Kullervo; Aubert, Isabelle (10 December 2021). "Transgene distribution and immune response after ultrasound delivery of rAAV9 and

Plasma gelsolin (9,144 words) [view diff] exact match in snippet view article find links to article

Edwin M; King, Michael A; Hughes, Jeffery A (September 2007). "Peripheral Transgene Expression of Plasma Gelsolin Reduces Amyloid in Transgenic Mouse Models

Jacob Hanna (5,562 words) [view diff] exact match in snippet view article find links to article

mesoderm cells and primitive endoderm cells without genetic modification, transgene or transcription factor over-expression, and has structural and morphological

GESTALT (2,706 words) [view diff] exact match in snippet view article find links to article

of eight in-tandem copies of a histone–green fluorescent protein (GFP) transgene. ScarTrace integrates scRNA-seq data for cell type analysis but instead

April–June 2020 in science (28,416 words) [view diff] exact match in snippet view article find links to article

G.; Maeng, Lisa Y.; Widge, Alik S.; Anikeeva, Polina (1 April 2020). "Transgene-free remote magnetothermal regulation of adrenal hormones". Science Advances