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searching for Transition state analog 15 found (25 total)

Abzyme (793 words) [view diff] no match in snippet view article find links to article

catalyzing the reaction. By raising an antibody to bind to a stable transition-state analog, a new and unique type of enzyme is produced. So far, all catalytic

Shikimate pathway (479 words) [view diff] exact match in snippet view article find links to article

Roundup, is a competitive inhibitor of EPSP synthase, acting as a transition state analog that binds more tightly to the EPSPS-S3P complex than PEP and inhibits

Forodesine (693 words) [view diff] no match in snippet view article find links to article

known as Immucillin H; trade names Mundesine and Fodosine) is a transition-state analog inhibitor of purine nucleoside phosphorylase studied for the treatment

Vanadate (1,169 words) [view diff] no match in snippet view article find links to article

ATPases, such as Na+/K+-ATPase and Ca2+-ATPase (PMCA). Acting as a transition-state analog of phosphate, vanadate undergoes nucleophillic attack by water

FHIT (747 words) [view diff] case mismatch in snippet view article find links to article

(FRAGILE HISTIDINE TRIAD PROTEIN) IN COMPLEX WITH ADENOSINE/SULFATE AMP ANALOG 4fit: FHIT-APO 5fit: FHIT-SUBSTRATE ANALOG 6fit: FHIT-TRANSITION STATE ANALOG

Renin (2,105 words) [view diff] case mismatch in snippet view article find links to article

RECOMBINANT GLYCOSYLATED HUMAN RENIN ALONE AND IN COMPLEX WITH A TRANSITION STATE ANALOG INHIBITOR 2g21: Ketopiperazine-Based Renin Inhibitors: Optimization

Adenosine deaminase (3,014 words) [view diff] no match in snippet view article find links to article

1991). "Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations". Science

Ferrochelatase (2,000 words) [view diff] exact match in snippet view article find links to article

competitive inhibitor with protoporphyrin IX and is thought to be a transition state analog. As such, N-MeMP has been used extensively as a stabilizing ligand

Chorismate mutase (1,354 words) [view diff] no match in snippet view article find links to article

importance in this reaction. In the chorismate mutase active site, the transition-state analog is stabilized by 12 electrostatic and hydrogen-bonding interactions

CKM (gene) (1,068 words) [view diff] exact match in snippet view article

v t e PDB gallery 2crk: MUSCLE CREATINE KINASE 1u6r: Transition state analog complex of muscle creatine kinase (R134K) mutant 1i0e: CRYSTAL STRUCTURE

HINT1 (1,031 words) [view diff] case mismatch in snippet view article find links to article

PKCI-1-ZINC 1kpb: PKCI-1-APO 1kpc: PKCI-1-APO+ZINC 1kpe: PKCI-TRANSITION STATE ANALOG 1kpf: PKCI-SUBSTRATE ANALOG 1rzy: Crystal structure of rabbit Hint

Lewis C. Cantley (3,257 words) [view diff] exact match in snippet view article find links to article

impurity in commercial preparations of ATP, vanadate, acts as a transition state analog for phosphate hydrolysis. In 1978 Cantley became assistant professor

PGM1 (2,064 words) [view diff] case mismatch in snippet view article find links to article

WITH CHEMICAL REACTION 1c4g: PHOSPHOGLUCOMUTASE VANADATE BASED TRANSITION STATE ANALOG COMPLEX 1jdy: RABBIT MUSCLE PHOSPHOGLUCOMUTASE 1lxt: STRUCTURE

Roland Douce (1,869 words) [view diff] exact match in snippet view article find links to article

isomeroreductase complexed with NADPH, two magnesium ions and a herbicidal transition state analog determined at 1.65 A resolution". EMBO J. 16 (12): 405–3415. doi:10

Transition state theory (5,817 words) [view diff] case mismatch in snippet view article find links to article

1995, 249, 284–312 Schramm, VL., Enzymatic Transition States and Transition State Analog Design. Annual Review of Biochemistry 1998, 67, 693–720 Schramm