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searching for Type I collagen 79 found (142 total)

Gingival fibers (380 words) [view diff] exact match in snippet view article find links to article

the tissue firmly against the teeth. They are primarily composed of type I collagen, although type III fibers are also involved. These fibers, unlike the

ZBTB7B (570 words) [view diff] exact match in snippet view article find links to article

finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g. COL1A1; MIM 120150) and has a role in development.[supplied

Osteoid (376 words) [view diff] exact match in snippet view article find links to article

composed of fibers and ground substance. The predominant type of fiber is type I collagen and comprises ninety percent of the osteoid. The ground substance is

Perichondrium (207 words) [view diff] exact match in snippet view article find links to article

functions in the growth and repair of cartilage. Perichondrium contains type I collagen and type XII collagen. Michael H. Ross. Histology: A Text and Atlas

Protein trimer (471 words) [view diff] exact match in snippet view article find links to article

macromolecules. Type II Collagen is an example of homotrimeric protein, while Type I collagen is an AAB-type heterotrimeric protein. Porins usually arrange themselves

Corpus albicans (345 words) [view diff] exact match in snippet view article find links to article

corpus luteum is being broken down by macrophages, fibroblasts lay down type I collagen, forming the corpus albicans. This process is called "luteolysis".

N-terminal telopeptide (371 words) [view diff] no match in snippet view article find links to article

The N-terminal telopeptide (NTX), also known as amino-terminal collagen crosslinks, is the N-terminal telopeptide of fibrillar collagens such as collagen

ZNF148 (1,032 words) [view diff] no match in snippet view article find links to article

BFCOL1 (binding factor of a type-I collagen promoter) zinc-finger transcription factor which binds to the two mouse type-I collagen gene promoters". The Biochemical

Sharpey's fibres (374 words) [view diff] exact match in snippet view article find links to article

of connective tissue consisting of bundles of strong predominantly type I collagen fibres connecting periosteum to bone. They are part of the outer fibrous

Deoxypyridinoline (205 words) [view diff] exact match in snippet view article find links to article

of two pyridinium cross-links that provide structural stiffness to type I collagen found in bones. It is excreted unmetabolized in urine and is a specific

PTRF (887 words) [view diff] no match in snippet view article find links to article

BFCOL1 (binding factor of a type-I collagen promoter) zinc-finger transcription factor which binds to the two mouse type-I collagen gene promoters". The Biochemical

Healing (1,359 words) [view diff] exact match in snippet view article find links to article

more spindly in appearance. They begin to produce the much stronger type I collagen. Some of the fibroblasts mature into myofibroblasts which contain the

Dermal fibroblast (1,527 words) [view diff] exact match in snippet view article find links to article

experimentally determined that pure type I collagen has a modulus of 5 GPa to 11.5 GPa. Therefore, pure type I collagen has nearly one million times greater

Feline cutaneous asthenia (922 words) [view diff] exact match in snippet view article find links to article

with the autosomal dominant form of feline cutaneous asthenia package type I collagen poorly. Collagen is a major component in skin tissue and in tendons

Discoidin domain-containing receptor 2 (1,397 words) [view diff] exact match in snippet view article find links to article

receptor 2 interacts with Src and Shc following its activation by type I collagen". J. Biol. Chem. 277 (21): 19206–12. doi:10.1074/jbc.M201078200. PMID 11884411

Biglycan (1,048 words) [view diff] exact match in snippet view article find links to article

Rauterberg J, Kresse H (February 1995). "Interaction of biglycan with type I collagen". J. Biol. Chem. 270 (6): 2776–83. doi:10.1074/jbc.270.6.2776. PMID 7852349

Nano-interfaces in bone (410 words) [view diff] case mismatch in snippet view article find links to article

(2009). "Nanomechanical Heterogeneity in the Gap and Overlap Regions of Type I Collagen Fibrils with Implications for Bone Heterogeneity". Biomacromolecules

Cornea (3,329 words) [view diff] exact match in snippet view article find links to article

membrane, Bowman's Layer is a tough layer composed of collagen (mainly type I collagen fibrils), laminin, nidogen, perlecan and other HSPGs that protects

Collagen receptor (1,090 words) [view diff] exact match in snippet view article find links to article

include integrin α10β2, which is situated on monocytes and binds type I collagen. Discoidin domain receptors form a subgroup of receptor tyrosine kinases

Tissue hydration (386 words) [view diff] exact match in snippet view article find links to article

hydration on nanoscale structural morphology and mechanics of individual Type I collagen fibrils in the Brtl mouse model of Osteogenesis Imperfecta". Journal

ZNF384 (636 words) [view diff] exact match in snippet view article find links to article

family of nuclear matrix transcription factors (NP/NMP4) that regulate type I collagen expression in osteoblasts". Journal of Bone and Mineral Research. 16

MKX (645 words) [view diff] exact match in snippet view article find links to article

embryos results in them developing hypoplastic tendons containing less type I collagen. MKX binds directly to the promoter of MyoD and represses its expression

Integrin alpha 2 (684 words) [view diff] exact match in snippet view article find links to article

alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagen". J. Biol. Chem. 276 (31): 29368–74. doi:10.1074/jbc.M104179200. PMID 11359786

Pycnodysostosis (1,417 words) [view diff] exact match in snippet view article find links to article

bone remodelling by degenerating the bone matrix proteins such as type I collagen, osteopontin, and osteonectin. Defective function of cathepsin K therefore

MMP16 (982 words) [view diff] exact match in snippet view article find links to article

regulates matrix metalloproteinase-dependent human melanoma invasion into type I collagen". J. Biol. Chem. 276 (22): 18786–94. doi:10.1074/jbc.M010053200. PMID 11278606

Platelet membrane glycoprotein (1,110 words) [view diff] exact match in snippet view article find links to article

alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagen". J. Biol. Chem. (United States) 276 (31): 29368–74. DOI:10.1074/jbc

Bone (8,829 words) [view diff] exact match in snippet view article find links to article

located on the surface of a bone. Osteoid is primarily composed of Type I collagen. Osteoblasts also manufacture hormones, such as prostaglandins, to

Corneal endothelium (1,193 words) [view diff] exact match in snippet view article find links to article

the corneal stroma disrupts the normally uniform periodic spacing of Type I collagen fibrils, creating light scatter. In addition, excessive corneal hydration

Weberian apparatus (1,398 words) [view diff] exact match in snippet view article find links to article

same histological composition of elastin and icthyocoll (a specific type I collagen), as established in a research by Rui Diogo. The Weberian apparatus

Interstitial collagenase (1,545 words) [view diff] exact match in snippet view article find links to article

alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagen". J. Biol. Chem. 276 (31): 29368–74. doi:10.1074/jbc.M104179200. PMID 11359786

Fibromodulin (1,257 words) [view diff] exact match in snippet view article find links to article

requirements for fibromodulin binding to collagen and the control of type I collagen fibrillogenesis--critical roles for disulphide bonding and the C-terminal

Pubic symphysis (1,563 words) [view diff] no match in snippet view article find links to article

Fibrocartilage is composed of small, chained bundles of thick, clearly defined, type I collagen fibers. This fibrous connective tissue bundles have cartilage cells

Mechanotherapy (993 words) [view diff] exact match in snippet view article find links to article

Langberg, Henning (2007-01-01). "Exercise-dependent IGF-I, IGFBPs, and type I collagen changes in human peritendinous connective tissue determined by microdialysis"

LARP6 (354 words) [view diff] exact match in snippet view article find links to article

the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen". J. Mol. Biol. 395 (2): 309–26. doi:10.1016/j.jmb.2009.11.020. PMC 2826804

CSPG4 (1,501 words) [view diff] exact match in snippet view article find links to article

regulates matrix metalloproteinase-dependent human melanoma invasion into type I collagen". The Journal of Biological Chemistry. 276 (22): 18786–94. doi:10.1074/jbc

Spermatogenesis associated 13 (300 words) [view diff] exact match in snippet view article find links to article

promotes myosin II-dependent contractility to inhibit cell migration on type I collagen". J. Cell Sci. 126 (Pt 24): 5585–97. doi:10.1242/jcs.131060. PMC 3860307

Tendinopathy (3,631 words) [view diff] exact match in snippet view article find links to article

inflammatory cytokines like IL-1β which reduces the expression of type I collagen mRNA in human tenocytes and causes extracellular matrix degradation

Myostatin (5,322 words) [view diff] exact match in snippet view article find links to article

imperfecta is due to a mutation that causes the production of abnormal Type I collagen. Mice with defective myostatin were created by replacing sequences

Dentin (3,607 words) [view diff] exact match in snippet view article find links to article

project into tiny tubules in the dentine. Pre-dentine is composed of 90% type I collagen and 10% non-collagenous proteins (including phosphoproteins, proteoglycans

Biopolymer (3,069 words) [view diff] exact match in snippet view article find links to article

stem cell proliferation in vitro. Gelatin: Gelatin is obtained from type I collagen consisting of cysteine, and produced by the partial hydrolysis of collagen

Glucosepane (3,323 words) [view diff] exact match in snippet view article find links to article

lysine-arginine derived advanced glycation end-product cross-linking in Type I collagen: A molecular dynamics simulation study". Biophysical Chemistry. 218:

Monoclonal gammopathy of undetermined significance (2,181 words) [view diff] exact match in snippet view article find links to article

significance--its effect on paraproteinemia and the urinary N-telopeptide of type I collagen bone turnover marker". Clinical Cancer Research. 15 (18): 5917–22.

Pancreatic stellate cell (2,479 words) [view diff] exact match in snippet view article find links to article

number, migrate and secrete extracellular matrix components such as type I collagen, chemokines and cytokines. Quiescent PaSCs produce metalloproteinases

Osteoclast (2,925 words) [view diff] exact match in snippet view article find links to article

Cathepsin K is the major protease involved in the degradation of type I collagen and other noncollagenous proteins. Mutations in the cathepsin K gene

Bone sialoprotein (2,049 words) [view diff] exact match in snippet view article find links to article

Tye CE, Hunter GK, Goldberg HA (April 2005). "Identification of the type I collagen-binding domain of bone sialoprotein and characterization of the mechanism

Sp7 transcription factor (2,875 words) [view diff] no match in snippet view article find links to article

disease has been in recessive osteogenesis imperfecta (OI), which is a type-I collagen related disease that causes a heterogeneous set of bone-related symptoms

Bone grafting (4,026 words) [view diff] exact match in snippet view article find links to article

volume 70–75% is HA mineral and 20% organic matrix, mostly fibrous type I collagen. Dentin, like bone, may release growth and differentiating factors

P4HA1 (883 words) [view diff] exact match in snippet view article find links to article

v t e PDB gallery 1tjc: Crystal structure of peptide-substrate-binding domain of human type I collagen prolyl 4-hydroxylase

Yu-Shan Lin (1,151 words) [view diff] case mismatch in snippet view article find links to article

Barbara (December 18, 2018). "Enzymatic Phosphorylation of Ser in a Type I Collagen Peptide". Biophysical Journal. 115 (12): 2327–2335. Bibcode:2018BpJ

TGF beta 1 (2,290 words) [view diff] exact match in snippet view article find links to article

interacts with TGF-beta but does not compete for decorin binding to type I collagen". Arch. Biochem. Biophys. 355 (2): 241–8. doi:10.1006/abbi.1998.0720

Joseph Paul Robinson (2,443 words) [view diff] case mismatch in snippet view article find links to article

Voytik-Harbin. 2002. "Tensile Mechanical Properties of Three-Dimensional Type I Collagen Extracellular Matrices with Varied Microstructure." Journal of Biomechanical

TPSAB1 (1,083 words) [view diff] exact match in snippet view article find links to article

Walls AF (1997). "Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts". J. Clin. Invest. 99 (6): 1313–21. doi:10

Nasal chondrocytes (2,863 words) [view diff] exact match in snippet view article find links to article

consisting of several layers of connective tissue fibers (mainly based on type I collagen) running parallel to the cartilage. Articular chondrocytes have typically

ITGB1BP1 (1,167 words) [view diff] exact match in snippet view article find links to article

3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway". J. Biol

Haptotaxis (2,092 words) [view diff] exact match in snippet view article find links to article

process. The haptotaxis is mediated by fibronectin, vitronectin, and type I collagen. A recent study has tentatively proposed the idea that the structures

Protein (11,210 words) [view diff] exact match in snippet view article find links to article

J (March 2008). "Mechanical properties of native and cross-linked type I collagen fibrils". Biophysical Journal. 94 (6): 2204–2211. doi:10.1529/biophysj

GroES (4,104 words) [view diff] exact match in snippet view article find links to article

S2CID 25856774. Mansell JP, Yarram SJ, Brown NL, Sandy JR (2002). "Type I collagen synthesis by human osteoblasts in response to placental lactogen and

UTSA College of Engineering and Integrated Design (1,199 words) [view diff] exact match in snippet view article find links to article

Biomedical engineering faculty work on topics such as the contribution of Type I collagen to mechanical properties of bone, importance of permeability in tissue

Alastair J Sloan (2,819 words) [view diff] exact match in snippet view article find links to article

Evaluation of dental pulp stem cell heterogeneity and behaviour in 3D type I collagen gels. Teoh L, Sloan AJ, McCullough MJ, Thompson W (2020). Measuring

Nanobiomechanics (1,240 words) [view diff] exact match in snippet view article find links to article

2009). "Nanomechanical heterogeneity in the gap and overlap regions of type I collagen fibrils with implications for bone heterogeneity". Biomacromolecules

Valvular heart disease (5,226 words) [view diff] exact match in snippet view article find links to article

regurgitation. Osteogenesis imperfecta is a disorder in formation of type I collagen and can also lead to chronic aortic regurgitation. Inflammation of

Tetrapeptide (1,938 words) [view diff] exact match in snippet view article find links to article

variety of extracellular matrix component including; fibronectin, type I collagen, type II collagen, laminin, and lens capsule basement membrane. By

Cucurbitacin E (1,179 words) [view diff] exact match in snippet view article find links to article

In vitro, cucurbitacin E inhibits the adhesion of cancer cells in type I collagen. In vitro, cucurbitacin E protects hepatocytes from CCl4 (carbon tetrachloride)

Meniscus tear (6,244 words) [view diff] exact match in snippet view article find links to article

between the tibial plateau and femoral condyles. The menisci contain 70% type I collagen. The larger semilunar medial meniscus is attached more firmly than

Jasvinder K Gambhir (933 words) [view diff] exact match in snippet view article find links to article

and ibandronate in postmenopausal osteoporotic women by assessing type I collagen C-telopeptide levels". Post Reproductive Health. 21 (2): 48–55. doi:10

Artificial bone (2,867 words) [view diff] exact match in snippet view article find links to article

biological agents is necessary to mimic the framework of the body. Type I collagen, which constitutes a significant portion of the organic mass of bone

Glyceryl octyl ascorbic acid (1,323 words) [view diff] exact match in snippet view article find links to article

has a proliferative effect on fibroblasts and a promoting effect on type I collagen production. GO-VC has a stronger melanin production inhibitory effect

C16orf90 (1,345 words) [view diff] exact match in snippet view article find links to article

"Glycation changes molecular organization and charge distribution in type I collagen fibrils". Scientific Reports. 10 (1): 3397. Bibcode:2020NatSR..10.3397B

Melinda Duer (2,260 words) [view diff] exact match in snippet view article find links to article

"Glycation changes molecular organization and charge distribution in type I collagen fibrils". Scientific Reports. 10 (1): 3397. doi:10.1038/S41598-020-60250-9

Role of skin in locomotion (3,559 words) [view diff] case mismatch in snippet view article find links to article

93–106. 1981 L. Yang. Mechanical properties of native and cross-linked type i collagen fibrils. Biophysical Journal, 94(6):2204–2211, March 2008. M R. Hebrank

Sum activity of peripheral deiodinases (4,203 words) [view diff] exact match in snippet view article find links to article

however in men only, the β-C-terminal cross-linked telopeptides of type I collagen (β-CTX). In the general population it is, however, positively associated

PEPD (3,545 words) [view diff] exact match in snippet view article find links to article

by fibroblasts, which is later replaced by type II collagen, then type I collagen. These changes indicate different stages of the wound-healing process

Thyroid's secretory capacity (5,004 words) [view diff] exact match in snippet view article find links to article

positive correlation to the β-C-terminal cross-linked telopeptides of type I collagen (β-CTX), a marker of bone resorption. In both diabetic and non-diabetic

Perlecan (11,011 words) [view diff] no match in snippet view article find links to article

membrane between fibroblasts in the stroma (in this case fibroblasts in a type-I collagen gel) and keratinocytes grown on top of the gel. Perlecan expression

Mir-25 microRNA precursor family (2,418 words) [view diff] exact match in snippet view article find links to article

HH, Yue PY, Mak NK, Wong RN (August 2012). "Ginsenoside Rb₁ induces type I collagen expression through peroxisome proliferator-activated receptor-delta"

Lidia Rudnicka (2,946 words) [view diff] exact match in snippet view article find links to article

topoisomerase I inhibitor, camptothecin, down-regulates the expression of type I collagen in fibroblasts of scleroderma patients and yields immunosuppressive

Daniel S. Greenspan (2,300 words) [view diff] exact match in snippet view article find links to article

biosynthetic processing of the precursor protein procollagen I into type I collagen, the most abundant protein in the bodies of vertebrates. The lab also

Cell encapsulation (8,785 words) [view diff] no match in snippet view article find links to article

to control distribution of cells inside the polymeric system. Thus, Type-I collagen obtained from animal tissues is now successfully being used commercially

Nerve guidance conduit (14,559 words) [view diff] exact match in snippet view article find links to article

technique can be used to create networks of fibers with diameters reaching type I collagen fiber diameters. The fibrous network created is randomly oriented and