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searching for adipogenesis 98 found (156 total)

Ciglitazone (424 words) [view diff] exact match in snippet view article find links to article

Inhibits HUVEC differentiation and angiogenesis and also stimulates adipogenesis and decreases osteoblastogenesis in human mesenchymal stem cells. Pershadsingh

ZNF423 (917 words) [view diff] exact match in snippet view article find links to article

in the cerebellum, as well as defects in olfactory development, and adipogenesis. Patients with mutations in ZNF423 have been reported in Joubert Syndrome

Mir-344 microRNA precursor family (215 words) [view diff] exact match in snippet view article find links to article

(May 2010). "A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin

Mir-322 microRNA precursor family (455 words) [view diff] exact match in snippet view article find links to article

(May 2010). "A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin

KLF15 (2,804 words) [view diff] exact match in snippet view article find links to article

overexpression in combination with insulin, glucocorticoid, and cAMP stimulated adipogenesis in H295R cells. In silico and RT-PCR analyses showed that the KLF15 gene

Chemerin (1,251 words) [view diff] exact match in snippet view article find links to article

Parmentier M, Sasaki S (Sep 2007). "Chemerin--a new adipokine that modulates adipogenesis via its own receptor". Biochem. Biophys. Res. Commun. 362 (4): 1013–8

Cathepsin (2,371 words) [view diff] exact match in snippet view article find links to article

human cathepsin V. Mouse cathepsin L has been shown to play a role in adipogenesis and glucose intolerance in mice. Cathepsin L degrades fibronectin, insulin

PRRX1 (1,265 words) [view diff] exact match in snippet view article find links to article

differentiation of mesenchymal precursors. For example, PRRX1 inhibits adipogenesis by activating transforming growth factor-beta (TGF-beta) signaling, and

Oprelvekin (1,474 words) [view diff] exact match in snippet view article find links to article

being produced in the bone marrow of healthy adults. Synonyms are: AGIF Adipogenesis inhibitory factor Interleukin-11 precursor. Oprelvekin is produced in

Bone morphogenetic protein 2 (1,370 words) [view diff] exact match in snippet view article find links to article

differentiation in a variety of cell types. BMP-2 may be involved in white adipogenesis and may have metabolic effects. Bone morphogenetic protein 2 has been

KMT2D (3,946 words) [view diff] exact match in snippet view article find links to article

requires KMT2D to establish a subset of adipogenic enhancers during adipogenesis. Depletion of KMT2D prior to differentiation prevents the accumulation

EBF1 (1,262 words) [view diff] exact match in snippet view article find links to article

"Gene expression analysis suggests that EBF-1 and PPARgamma2 induce adipogenesis of NIH-3T3 cells with similar efficiency and kinetics". Physiol. Genomics

Senotherapy (1,261 words) [view diff] exact match in snippet view article find links to article

White TA, et al. (December 2015). "Targeting senescent cells enhances adipogenesis and metabolic function in old age". eLife. 4: e12997. doi:10.7554/eLife

Bone morphogenetic protein 7 (2,565 words) [view diff] exact match in snippet view article find links to article

humans may be developed as a result. BMP7 not only stimulates brown adipogenesis, it also stimulates the "browning" of brite or beige adipocytes, turning

NRIP1 (2,697 words) [view diff] exact match in snippet view article find links to article

1b. Estrogen-related receptor alpha (ERRa) can activate RIP140 during adipogenesis, by means of directly binding to an estrogen receptor element/ERR element

ZBTB7A (821 words) [view diff] exact match in snippet view article find links to article

of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis". J. Biol. Chem. 279 (12): 11711–8. doi:10.1074/jbc.M310240200. PMC 4303998

KLF3 (1,303 words) [view diff] exact match in snippet view article find links to article

disruption of the basic Kruppel-like factor gene (Klf3) reveals a role in adipogenesis". Mol Cell Biol. 28 (12): 3967–78. doi:10.1128/MCB.01942-07. PMC 2423134

Taraxacum (4,936 words) [view diff] exact match in snippet view article find links to article

components play a significant role in the control of lipid metabolism and adipogenesis, which means dandelion can potentially be used to treat obesity. Dandelion

Seipin (2,022 words) [view diff] exact match in snippet view article find links to article

with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis". Molecular Metabolism. 4 (3): 199–209. doi:10.1016/j.molmet.2014.12

Taraxacum (4,936 words) [view diff] exact match in snippet view article find links to article

components play a significant role in the control of lipid metabolism and adipogenesis, which means dandelion can potentially be used to treat obesity. Dandelion

Bone morphogenetic protein (3,436 words) [view diff] exact match in snippet view article find links to article

(GDFs). BMPs are also involved in adipogenesis and functional regulation of adipose tissue. BMP4 favors white adipogenesis, whereas BMP7 activates brown fat

Bruce M. Spiegelman (1,141 words) [view diff] exact match in snippet view article find links to article

P.; Hu, E.; Spiegelman, B. M. (December 30, 1994). "Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor"

OP9 cell (941 words) [view diff] exact match in snippet view article find links to article

adipocytes after expressing marker proteins and may contribute to a novel adipogenesis model. The mRNA expression of adipsin and PPARy2 in OP9 cells confirm

ADAM12 (1,579 words) [view diff] exact match in snippet view article find links to article

Loechel F, Albrechtsen R, Wewer UM (2002). "ADAM 12 protease induces adipogenesis in transgenic mice". Am. J. Pathol. 160 (5): 1895–903. doi:10

COUP-TFII (1,548 words) [view diff] exact match in snippet view article find links to article

upstream promoter-transcription factor II is a critical regulator of adipogenesis". Proc. Natl. Acad. Sci. U.S.A. 105 (7): 2421–6. Bibcode:2008PNAS..105

PER3 (1,507 words) [view diff] exact match in snippet view article find links to article

phase syndrome. The length polymorphism has also been shown to inhibit adipogenesis and Per3 knockout mice were shown to have increased adipose tissue and

THRAP3 (780 words) [view diff] exact match in snippet view article find links to article

"Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis". Nature. 417 (6888): 563–7. Bibcode:2002Natur.417..563G. doi:10.1038/417563a

White adipose tissue (934 words) [view diff] exact match in snippet view article find links to article

factors that promotes gene expression. PPARγ is required for both the adipogenesis and maintenance of the adipocytes. White adipose tissue exists in various

Sodium pyruvate (342 words) [view diff] exact match in snippet view article find links to article

KH, Cho H, Han IO (2015-11-19). "Exogenous Sodium Pyruvate Stimulates Adipogenesis of 3T3-L1 Cells". Journal of Cellular Biochemistry. 117 (1): 39–48. doi:10

Ligustrum japonicum (808 words) [view diff] exact match in snippet view article find links to article

intracellular triglycerides are well-known markers of osteoclastogenesis and adipogenesis. The increase in ALP is due to the substances within the fruits of Ligustrum

MYF5 (2,355 words) [view diff] exact match in snippet view article find links to article

muscle formation. Although the specific roles and dependency of Myf5 in adipogenesis and neurogenesis have remained to be explored, these findings show that

GPAT4 (432 words) [view diff] exact match in snippet view article find links to article

regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis". J. Lipid Res. 51 (7): 1971–81. doi:10.1194/jlr.M006304. PMC 2882735

Cyclin D1 (5,694 words) [view diff] exact match in snippet view article find links to article

D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment". primary. The Journal of Biological

Obesogen (6,277 words) [view diff] exact match in snippet view article find links to article

Peroxisome Proliferator-activated Receptor γ Modulator That Promotes Adipogenesis". J. Biol. Chem. 282 (26): 19152–19166. doi:10.1074/jbc.M702724200. PMID 17468099

Follistatin (2,169 words) [view diff] exact match in snippet view article find links to article

Decaunes P, et al. (August 2009). "Role of follistatin in promoting adipogenesis in women". The Journal of Clinical Endocrinology and Metabolism. 94 (8):

Adipose tissue (8,489 words) [view diff] exact match in snippet view article find links to article

observing the chromatin landscapes of beige adipocytes have found that adipogenesis of these cells results from the formation of cell specific chromatin

Thiazolidinedione (2,133 words) [view diff] exact match in snippet view article find links to article

histological improvements in steatosis severity. Thiazolindinediones induce adipogenesis in subcutaneous fat deposits by activating PPARγ receptors. This effect

Tropomodulin (1,575 words) [view diff] exact match in snippet view article find links to article

regulates thin filament length and can switch between myogenesis and adipogenesis. TMOD4 Function has at least one point in common with the protein LMOD3

Adenovirus serotype 36 (694 words) [view diff] exact match in snippet view article find links to article

Fusinski KA, Rathod MA, et al. (2007). "Human adenovirus Ad-36 induces adipogenesis via its E4 orf-1 gene". Int J Obes (Lond). 32 (3): 397–406. doi:10.1038/sj

GEFT (508 words) [view diff] exact match in snippet view article find links to article

BB, Liu M (2006). "Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT". Mol. Cell

Asprosin (2,349 words) [view diff] exact match in snippet view article find links to article

I, Arner P, Summers KM (September 2016). "Expression of FBN1 during adipogenesis: Relevance to the lipodystrophy phenotype in Marfan syndrome and related

CTBP2 (1,974 words) [view diff] exact match in snippet view article find links to article

"C-terminal binding protein: A metabolic sensor implicated in regulating adipogenesis". Int. J. Biochem. Cell Biol. 43 (5): 693–6. doi:10.1016/j.biocel.2011

Banting Lectures (629 words) [view diff] exact match in snippet view article find links to article

or Consequence?, Barbara E. Corkey, PMID 22187369 2012: Regulation of Adipogenesis: Toward New Therapeutics for Metabolic Disease, Bruce M. Spiegelman,

TSC22D3 (1,186 words) [view diff] exact match in snippet view article find links to article

2003). "A glucocorticoid-induced leucine-zipper protein, GILZ, inhibits adipogenesis of mesenchymal cells". EMBO Reports. 4 (4): 374–80. doi:10.1038/sj.embor

Metadoxine (1,907 words) [view diff] exact match in snippet view article find links to article

thereby repressing CCAAT/enhancer-binding protein b during hormone-induced adipogenesis. Metadoxine, when given in an immediate release form in doses from 300 mg

Perfluorodecanoic acid (3,380 words) [view diff] exact match in snippet view article find links to article

concentration in humans. It is however unknown how PFDA might affect adipogenesis. HepG2 cells and 3T3-L1 differentiation model were used to detect the

HMGA2 (2,893 words) [view diff] exact match in snippet view article find links to article

rearrangement of this gene that are associated with lipomas suggests a role in adipogenesis and mesenchymal differentiation. A gene knock-out study of the mouse

Noggin (protein) (2,327 words) [view diff] exact match in snippet view article

Ponnazhagan S (April 2012). "Noggin is novel inducer of mesenchymal stem cell adipogenesis: implications for bone health and obesity". The Journal of Biological

N6-Methyladenosine (5,572 words) [view diff] exact match in snippet view article find links to article

demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis". Cell Research. 24 (12): 1403–1419. doi:10.1038/cr.2014.151. PMC 4260349

Claudia Fischbach (700 words) [view diff] exact match in snippet view article find links to article

career Institutions Cornell University Harvard University Thesis Adipose tissue engineering development of a 3-D model system of adipogenesis. (2004)

MED6 (1,314 words) [view diff] exact match in snippet view article find links to article

"Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis". Nature. 417 (6888): 563–567. Bibcode:2002Natur.417..563G. doi:10.1038/417563a

TAF8 (926 words) [view diff] exact match in snippet view article find links to article

early embryonic mouse development, is an inducible TAFII implicated in adipogenesis". Mol. Cell. 12 (4): 991–1001. doi:10.1016/S1097-2765(03)00396-4. PMID 14580349

MED21 (1,238 words) [view diff] exact match in snippet view article find links to article

"Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis". Nature. 417 (6888): 563–7. Bibcode:2002Natur.417..563G. doi:10.1038/417563a

Adenoviridae (5,557 words) [view diff] exact match in snippet view article find links to article

D) gastroenteritis (HAdV-F types 40, 41, HAdV-G type 52) obesity or adipogenesis (HAdV-A type 31, HAdV-C type 5, HAdV-D types 9, 36, 37) All these types

Adenovirus infection (2,734 words) [view diff] exact match in snippet view article find links to article

SMAM1, have at least some evidence of causation of obesity in animals, adipogenesis in cells, and/or association with human obesity.[better source needed]

Agouti-signaling protein (3,312 words) [view diff] exact match in snippet view article find links to article

ISBN 978-0-12-227080-2, retrieved 2019-09-19 Spiegelman BM, Flier JS (November 1996). "Adipogenesis and obesity: rounding out the big picture". Cell. 87 (3): 377–89. doi:10

Genetics of obesity (2,298 words) [view diff] exact match in snippet view article find links to article

which in turn, inhibits the activity of C/EBPα, an early inducer of adipogenesis. KLF14 ? Although it does not play a role in the formation of fat itself

MED12 (1,753 words) [view diff] exact match in snippet view article find links to article

"Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis". Nature. 417 (6888): 563–7. Bibcode:2002Natur.417..563G. doi:10.1038/417563a

Acetyl-CoA carboxylase (2,988 words) [view diff] exact match in snippet view article find links to article

2002). "A biotin analog inhibits acetyl-CoA carboxylase activity and adipogenesis". The Journal of Biological Chemistry. 277 (19): 16347–16350. doi:10

STC1 (1,179 words) [view diff] exact match in snippet view article find links to article

Andersson LC (Jun 2004). "Upregulated expression of stanniocalcin-1 during adipogenesis". Experimental Cell Research. 296 (2): 256–64. doi:10.1016/j.yexcr.2004

STC1 (1,179 words) [view diff] exact match in snippet view article find links to article

Andersson LC (Jun 2004). "Upregulated expression of stanniocalcin-1 during adipogenesis". Experimental Cell Research. 296 (2): 256–64. doi:10.1016/j.yexcr.2004

Oxylipin (1,624 words) [view diff] exact match in snippet view article find links to article

G, Klingenspor M, Langin D, Amri EZ, et al. (May 2017). "Control of adipogenesis by oxylipins, GPCRs and PPARs" (PDF). Biochimie. 136: 3–11. doi:10.1016/j

MED17 (1,220 words) [view diff] exact match in snippet view article find links to article

"Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis". Nature. 417 (6888): 563–7. Bibcode:2002Natur.417..563G. doi:10.1038/417563a

MicroRNA 196a-2 (663 words) [view diff] exact match in snippet view article find links to article

G, Nimura K, Kaneda Y (2012). "Essential role for miR-196a in brown adipogenesis of white fat progenitor cells". PLOS Biology. 10 (4): e1001314. doi:10

MED14 (1,446 words) [view diff] exact match in snippet view article find links to article

"Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis". Nature. 417 (6888): 563–7. Bibcode:2002Natur.417..563G. doi:10.1038/417563a

INSIG2 (1,582 words) [view diff] exact match in snippet view article find links to article

Kim KA, Kwon KB, Park JW, Park BH (May 2009). "Silibinin attenuates adipogenesis in 3T3-L1 preadipocytes through a potential upregulation of the insig

Brown adipose tissue (5,029 words) [view diff] exact match in snippet view article find links to article

Alexander (January 2024). "EPAC1 enhances brown fat growth and beige adipogenesis". Nature Cell Biology. 26 (1): 113–123. doi:10.1038/s41556-023-01311-9

Diacylglycerol O-acyltransferase 2 (629 words) [view diff] exact match in snippet view article find links to article

CAAT/enhancer-binding protein beta (C/EBPbeta) and C/EBPalpha during adipogenesis". J. Biol. Chem. 282 (29): 21005–14. doi:10.1074/jbc.M702871200. PMC 2254492

Sirtuin 2 (3,442 words) [view diff] exact match in snippet view article find links to article

targets play important roles in metabolic homeostasis. SIRT2 inhibits adipogenesis by deacetylating FOXO1 and thus may protect against insulin resistance

Senile osteoporosis (3,437 words) [view diff] exact match in snippet view article find links to article

Rivas D, Duque G (December 2009). "Effect of estrogens on bone marrow adipogenesis and Sirt1 in aging C57BL/6J mice". Biogerontology. 10 (6): 747–55. doi:10

Robert G. Roeder (2,339 words) [view diff] exact match in snippet view article find links to article

"Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis". Nature. 417 (6888): 563–7. Bibcode:2002Natur.417..563G. doi:10.1038/417563a

Phytoestrogen (3,866 words) [view diff] exact match in snippet view article find links to article

activation of ERs and PPARs determines daidzein-induced osteogenesis and adipogenesis". Journal of Bone and Mineral Research. 19 (5): 853–61. doi:10.1359/jbmr

TAB1 (2,250 words) [view diff] exact match in snippet view article find links to article

Shibuya H, Gotoh Y, Matsumoto K, Kato S (2003). "Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade". Nat. Cell

Stem-cell therapy (9,576 words) [view diff] exact match in snippet view article find links to article

Ye H, Shakibaei M (December 2007). "Chondrogenesis, osteogenesis and adipogenesis of canine mesenchymal stem cells: a biochemical, morphological and ultrastructural

CUL3 (2,387 words) [view diff] exact match in snippet view article find links to article

"Cul3 neddylation is crucial for gradual lipid droplet formation during adipogenesis". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1864

Sonic hedgehog protein (7,133 words) [view diff] exact match in snippet view article find links to article

regrowing hair cells after damage. SHH is important for regulating dermal adipogenesis by hair follicle transit-amplifying cells (HF-TACs). Specifically, SHH

Hyperandrogenism (6,203 words) [view diff] exact match in snippet view article find links to article

Additionally, obesity elevates inflammatory adipokines which leads to not only adipogenesis, but also heightened insulin resistance. Cushing's syndrome develops

FOSB (7,188 words) [view diff] exact match in snippet view article find links to article

DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis". Nature Medicine. 6 (9): 985–90. doi:10.1038/79683. PMID 10973317. S2CID 20302360

RBM4 (2,376 words) [view diff] exact match in snippet view article find links to article

Ma C, et al. (July 2022). "RNA-Binding Proteins in the Regulation of Adipogenesis and Adipose Function". Cells. 11 (15): 2357. doi:10.3390/cells11152357

Let-7 microRNA precursor (8,297 words) [view diff] exact match in snippet view article find links to article

Kliewer SA, Mangelsdorf DJ (June 2009). "MicroRNA let-7 regulates 3T3-L1 adipogenesis". Molecular Endocrinology. 23 (6): 925–931. doi:10.1210/me.2008-0298

Transforming growth factor beta (8,680 words) [view diff] exact match in snippet view article find links to article

"RepSox, a small molecule inhibitor of the TGFβ receptor, induces brown adipogenesis and browning of white adipocytes". Acta Pharmacologica Sinica. 40 (12):

Free fatty acid receptor 4 (7,729 words) [view diff] exact match in snippet view article find links to article

Y, Zhou Y, Wei H, Peng J (August 2017). "GPR120: a critical role in adipogenesis, inflammation, and energy metabolism in adipose tissue". Cellular and

Shaodong Guo (1,073 words) [view diff] exact match in snippet view article find links to article

Zheng, M.; Cai, D.; Liu, J.; Guo, S. (2019). "Ginsenoside Rg2 inhibits adipogenesis in 3T3-L1 preadipocytes and suppresses obesity in high-fat-diet-induced

List of capsaicinoids (743 words) [view diff] exact match in snippet view article find links to article

(June 2015). "Nonivamide enhances miRNA let-7d expression and decreases adipogenesis PPARγ expression in 3T3-L1 cells". Journal of Cellular Biochemistry.

Eric J. Nestler (3,748 words) [view diff] exact match in snippet view article find links to article

DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis". Nature Medicine. 6 (9): 985–990. doi:10.1038/79683. PMID 10973317.

Anabolic steroid (21,564 words) [view diff] exact match in snippet view article find links to article

(November 2003). "Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated

3D cell culturing by magnetic levitation (1,663 words) [view diff] exact match in snippet view article find links to article

endothelial cells, as well as perivascular localization of ASC. Upon adipogenesis induction of either 3T3-L1 adipospheres or adipospheres derived from

Jeffrey Flier (3,580 words) [view diff] exact match in snippet view article find links to article

1373 times, June 2022 Spiegelman, B. M.; Flier, J. S. (1996-11-01). "Adipogenesis and obesity: rounding out the big picture". Cell. 87 (3): 377–389. doi:10

Yihai Cao (1,266 words) [view diff] exact match in snippet view article find links to article

ISSN 1524-4571. PMID 15155527. Cao, Yihai (2007-09-01). "Angiogenesis modulates adipogenesis and obesity". The Journal of Clinical Investigation. 117 (9): 2362–2368

Bruce Beutler (12,100 words) [view diff] exact match in snippet view article find links to article

reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis". Cell Metabolism. 34 (11): 1860–1874.e4. doi:10.1016/j.cmet.2022.09

MAP4K4 (3,301 words) [view diff] exact match in snippet view article find links to article

interference-based screen identifies MAP4K4/NIK as a negative regulator of PPARgamma, adipogenesis, and insulin-responsive hexose transport". Proceedings of the National

Nutriepigenomics (4,722 words) [view diff] exact match in snippet view article find links to article

the specific target genes have yet to be identified. Genes involved in adipogenesis, such as fibroblast growth-factor-2, phosphatase and tensin homologue

Super-enhancer (4,359 words) [view diff] exact match in snippet view article find links to article

2014). "Molecular architecture of transcription factor hotspots in early adipogenesis". Cell Reports. 7 (5): 1434–42. doi:10.1016/j.celrep.2014.04.043. PMC 6360525

Bone marrow adipose tissue (5,152 words) [view diff] exact match in snippet view article find links to article

marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis". Endocrinology. 148 (5): 2553–2562. doi:10.1210/en.2006-1704. PMID 17317771

In vivo bioreactor (3,275 words) [view diff] exact match in snippet view article find links to article

effect of FGF-1 loaded alginate microbeads on neovascularization and adipogenesis in a vascular pedicle model of adipose tissue engineering". Biomaterials

Etrinabdione (492 words) [view diff] exact match in snippet view article find links to article

(October 2018). "VCE-004.8, A Multitarget Cannabinoquinone, Attenuates Adipogenesis and Prevents Diet-Induced Obesity". Scientific Reports. 8 (1): 16092

BRB-seq (1,751 words) [view diff] exact match in snippet view article find links to article

Deplancke, Bart (2018-06-20). "A stromal cell population that inhibits adipogenesis in mammalian fat depots". Nature. 559 (7712): 103–108. Bibcode:2018Natur

Peter Tontonoz (2,987 words) [view diff] exact match in snippet view article find links to article

AHA Tontonoz, P., Hu, E., & Spiegelman, B. M. (1994). Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell