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Find link is a tool written by Edward Betts.Longer titles found: Electrochemical aptamer-based biosensors (view), L-Ribonucleic acid aptamer (view), Anti-thrombin aptamers (view), Spinach aptamer (view)
searching for aptamer 91 found (161 total)
alternate case: Aptamer
Glycine riboswitch
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usually consist of two metabolite-binding aptamer domains with similar structures in tandem. The aptamers were originally thought to cooperatively bindSAM riboswitch (S-box leader) (993 words) [view diff] exact match in snippet view article
the downstream gene. When S-Adenosyl methionine (SAM) is bound to the aptamer, the anti-terminator is sequestered by an anti-anti-terminator; the terminatorHeat shock factor (743 words) [view diff] exact match in snippet view article find links to article
PMID 19112021. Salamanca HH, Fuda N, Shi H, Lis JT (August 2011). "An RNA aptamer perturbs heat shock transcription factor activity in Drosophila melanogaster"YkoK leader (320 words) [view diff] exact match in snippet view article find links to article
3D representation of the Ykok leader. Structure of the M-box riboswitch aptamer domain from Bacillus subtilis. Barrick, JE; Corbino KA; Winkler WC; NahviCapillary electrophoresis (4,675 words) [view diff] exact match in snippet view article find links to article
IL-1α and the aptamer. Huang et al. uses ACE to investigate protein-protein interactions using aptamers. A α-thrombin binding aptamer was labeled withMesoplasma florum riboswitch (249 words) [view diff] exact match in snippet view article find links to article
in sequence and structure within the loops regions that are required in aptamer binding compared to conventional purine riboswitches. Mutagenesis confirmedPotential of mean force (679 words) [view diff] exact match in snippet view article find links to article
to show that potential of mean force decreases between thrombin and its aptamer (a protein-ligand complex) under the effect of electrical fields. StatisticalDose (biochemistry) (2,601 words) [view diff] exact match in snippet view article
cocaine levels in undiluted blood serum with electrochemical aptamer-based sensing. DNA aptamers, which are peptides that have with specific target moleculesExosite (282 words) [view diff] exact match in snippet view article find links to article
Mayer, Günter; Pötzsch, Bernd (April 2009). "An Exosite-Specific ssDNA Aptamer Inhibits the Anticoagulant Functions of Activated Protein C and EnhancesAggregation-induced emission (620 words) [view diff] exact match in snippet view article find links to article
detection based on supraparticle copper nanoclusters formed on bivalent aptamer". Biosensors and Bioelectronics. 132: 186–195. doi:10.1016/j.bios.2019Base pair (3,677 words) [view diff] exact match in snippet view article find links to article
pair to DNA aptamer generation by in vitro selection (SELEX) and demonstrated the genetic alphabet expansion significantly augment DNA aptamer affinitiesNako Nakatsuka (649 words) [view diff] exact match in snippet view article find links to article
alongside Paul Weiss and Anne M. Andrews. Her doctoral research considered aptamer-functionalised field effect transistors for serotonin and dopamine sensingKary Mullis (4,851 words) [view diff] exact match in snippet view article find links to article
linker synthesized with an alpha-1,3-gal-gal bond on one end and a DNA aptamer devised to bind specifically to the strain of influenza you have on theMalachite green (1,766 words) [view diff] exact match in snippet view article find links to article
green. For example, Zhao et al., demonstrated the use of malachite green aptamer in microcantilever based sensors to detect low concentration of malachiteMidkine (2,372 words) [view diff] exact match in snippet view article find links to article
its cancerous proliferation properties. Drugs by the name of anti-cancer aptamers have been created to inhibit to proteins involved in MK's cancer cell "activation"Force spectroscopy (2,787 words) [view diff] exact match in snippet view article find links to article
binding force between thrombin, a blood coagulation protein, and its DNA aptamer. A recently developed technique, acoustic force spectroscopy (AFS), allowsCantilever (2,120 words) [view diff] exact match in snippet view article find links to article
Sensitivity of Label Free Microcantilever Based Biosensor Using Malachite Green Aptamer". Sensors and Actuators B: Chemical. 300. doi:10.1016/j.snb.2019.126963Antibody mimetic (732 words) [view diff] exact match in snippet view article find links to article
"Rapid identification and development of SARS-CoV-2 selective Optimers". Aptamer Group. 11 December 2020. Retrieved 2021-08-03. Hantschel O (2017-11-20)Xenobiology (4,530 words) [view diff] exact match in snippet view article find links to article
pair to DNA aptamer generation by in vitro selection (SELEX) and demonstrated the genetic alphabet expansion significantly augment DNA aptamer affinitiesThrombodynamics test (663 words) [view diff] exact match in snippet view article find links to article
et al. (2011). "Improvement of spatial fibrin formation by the anti-TFPI aptamer BAX499: changing clot size by targeting extrinsic pathway initiation".Recombinase polymerase amplification (1,704 words) [view diff] exact match in snippet view article find links to article
DNA or RNA, pathogenic bacterial genomic DNA, as well as short length aptamer DNA. The three core RPA enzymes can be supplemented by further enzymesPreQ1-II riboswitch (220 words) [view diff] exact match in snippet view article find links to article
Garcia GA, Breaker RR (2008). "Confirmation of a second natural preQ1 aptamer class in Streptococcaceae bacteria". RNA. 14 (4): 685–695. doi:10.1261/rnaSAM-II riboswitch (287 words) [view diff] exact match in snippet view article find links to article
Meyer MM, Ames TD, Breaker RR (November 2009). "A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria". RNA. 15 (11):Teresa Przytycka (512 words) [view diff] exact match in snippet view article find links to article
reconstruction, regulatory roles of DNA conformation dynamics and RNA aptamer analysis". Birth year from VIAF authority control record, retrieved 2021-12-12SAM-IV riboswitch (292 words) [view diff] exact match in snippet view article find links to article
SAM-VI riboswitch Weinberg Z, Regulski EE, Hammond MC, et al. (2008). "The aptamer core of SAM-IV riboswitches mimics the ligand-binding site of SAM-I riboswitches"Microscale thermophoresis (1,536 words) [view diff] exact match in snippet view article find links to article
(2010). "Optical thermophoresis for quantifying the buffer dependence of aptamer binding". Angew. Chem. Int. Ed. Engl. 49 (12): 1–5. doi:10.1002/anie.200903998Tetrahydrofolate riboswitch (313 words) [view diff] exact match in snippet view article find links to article
tetrahydrofolate-sensing riboswitch reveals two ligand binding sites in a single aptamer". Structure. 19 (10): 1413–1423. doi:10.1016/j.str.2011.06.019. PMC 3196276Surface plasmon resonance microscopy (7,716 words) [view diff] exact match in snippet view article find links to article
Aptamers are particular DNA ligands that target biomolecules such as proteins. SPR imaging platform would be a good choice to characterize aptamer -proteinRNA world (10,688 words) [view diff] exact match in snippet view article find links to article
classes have highly conserved aptamer domains, even among diverse organisms. When a target metabolite is bound to this aptamer, conformational changes occurMS2 tagging (746 words) [view diff] exact match in snippet view article find links to article
Urlaub H, Vogel J (November 2009). "In vivo expression and purification of aptamer-tagged small RNA regulators". Nucleic Acids Research. 37 (20): e133. doi:10DNA-binding protein (2,565 words) [view diff] exact match in snippet view article find links to article
(2016). "Electrical Stimulus Controlled Binding/Unbinding of Human Thrombin-Aptamer Complex". Sci. Rep. 6: 37449. Bibcode:2016NatSR...637449G. doi:10.1038/srep37449PreQ1-III riboswitch (241 words) [view diff] exact match in snippet view article find links to article
(2015). "Structural analysis of a class III preQ1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics". ProcBiosensor (12,037 words) [view diff] exact match in snippet view article find links to article
typically consists of a bio-receptor (enzyme/antibody/cell/nucleic acid/aptamer), transducer component (semi-conducting material/nanomaterial), and electronicNucleic acid analogue (5,268 words) [view diff] exact match in snippet view article find links to article
pair to DNA aptamer generation by in vitro selection (SELEX) and demonstrated the genetic alphabet expansion significantly augment DNA aptamer affinitiesCarlotta Guiducci (957 words) [view diff] exact match in snippet view article find links to article
Carlotta (2018-06-30). "Comparison against current standards of a DNA aptamer for the label-free quantification of tobramycin in human sera employedLigand (biochemistry) (3,144 words) [view diff] exact match in snippet view article
2010). "Optical thermophoresis for quantifying the buffer dependence of aptamer binding". Angewandte Chemie. 49 (12): 2238–2241. doi:10.1002/anie.200903998Molecular dynamics (9,834 words) [view diff] exact match in snippet view article find links to article
and even to show the effect of electric field on thrombin (protein) and aptamer (nucleotide) complex among many other interesting studies. Molecular dynamicsHapten (2,512 words) [view diff] exact match in snippet view article find links to article
Laboratory. (2009). Affinity probe capillary electrophoresis evaluation of aptamer binding to Campylobacter jejuni bacteria(ARL-TR (Aberdeen Proving GroundNFKB1 (2,363 words) [view diff] case mismatch in snippet view article find links to article
1ooa: CRYSTAL STRUCTURE OF NF-kB(p50)2 COMPLEXED TO A HIGH-AFFINITY RNA APTAMER 1svc: NFKB P50 HOMODIMER BOUND TO DNA 1u36: Crystal structure of WLAC mutantChaperone (protein) (3,499 words) [view diff] exact match in snippet view article
"Inhibiting heat shock factor 1 in human cancer cells with a potent RNA aptamer". PLOS ONE. 9 (5): e96330. Bibcode:2014PLoSO...996330S. doi:10.1371/journalBio-FET (2,537 words) [view diff] exact match in snippet view article find links to article
ISSN 1364-5528. PMID 12375833. Massey, Roslyn; Bebe. S; Prakash, R (July 2020). "Aptamer-Enhanced Organic Electrolyte-Gated FET Biosensor for High-Specificity DetectionZFYVE16 (689 words) [view diff] exact match in snippet view article find links to article
signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA". Molecular Biology of the Cell. 17 (9): 3819–31. doi:10.1091/mbcCandidatus Pelagibacter communis (1,931 words) [view diff] exact match in snippet view article find links to article
E; Meyer MM; Ames TD; Breaker RR (November 2009). "A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria". RNA. 15 (11):Receptor–ligand kinetics (1,127 words) [view diff] exact match in snippet view article find links to article
2021). "Impact of the Coverage of Aptamers on a Nanoparticle on the Binding Equilibrium and Kinetics between Aptamer and Protein". ACS Sensors. 6 (2):Cytochrome c (3,790 words) [view diff] exact match in snippet view article find links to article
619. PMID 9558479. Loo JF, Lau PM, Ho HP, Kong SK (October 2013). "An aptamer-based bio-barcode assay with isothermal recombinase polymerase amplificationPharmacokinetics (4,401 words) [view diff] exact match in snippet view article find links to article
2010). "Optical thermophoresis for quantifying the buffer dependence of aptamer binding". Angewandte Chemie. 49 (12): 2238–41. doi:10.1002/anie.200903998Jennifer M. Heemstra (956 words) [view diff] exact match in snippet view article find links to article
molecules. She has demonstrated that nucleic acid aptamers can be used in biosensing. In particular, split aptamers can self-assemble when particular small moleculesEster H. Segal (2,159 words) [view diff] exact match in snippet view article find links to article
engineered with specific surface functions (e.g. attached proteins, enzymes, aptamers, and antimicrobial peptides) to enhance the limits of detection for analytesPolymerase chain reaction optimization (2,030 words) [view diff] exact match in snippet view article find links to article
incubation times for polymerase activation, compared with antibody or aptamer-based hot-start PCRs.[citation needed] Other methods to increase specificityMarcin Kortylewski (1,070 words) [view diff] exact match in snippet view article find links to article
methods of use thereof US 10,711,272 US 11,186,840 CTLA-4 aptamer siRNA species CTLA-4 Aptamer Conjugates US 10,801,026 Compounds and compositions includingLocalized surface plasmon (1,370 words) [view diff] exact match in snippet view article find links to article
Lun; Lau, Pui Man; Yong, Ken-Tye; Ho, Ho Pui; Kong, Siu Kai (2017). "An Aptamer Bio-barCode (ABC) assay using SPR, RNase H, and probes with RNA and gold-nanorodsPSMC2 (2,572 words) [view diff] exact match in snippet view article find links to article
Kakiuchi N, Shimotohno K, Taira K, Kusakabe I, Nishikawa S (2001). "The RNA aptamer-binding site of hepatitis C virus NS3 protease". Biochem. Biophys. ResBai Chunli (1,847 words) [view diff] exact match in snippet view article find links to article
Jiang, Y.; Zhu, C.; Ling, L.; Wan, L.; Fang, X.; Bai, C. (2003). "Specific Aptamer−Protein Interaction Studied by Atomic Force Microscopy". Analytical ChemistryRegulation of gene expression (5,229 words) [view diff] exact match in snippet view article find links to article
depending on certain conditions, such as temperature or presence of a ligand (aptamer). Some transcripts act as ribozymes and self-regulate their expressionUniversity of Louisville School of Medicine (2,587 words) [view diff] exact match in snippet view article find links to article
Kentucky's abundant crops. First clinical use of G-rich oligonucleotide aptamer therapy for cancer Drs. Trent and Bates discovered a new growth inhibitorDNA binding site (2,168 words) [view diff] exact match in snippet view article find links to article
D (Feb 2010). "Optical Thermophoresis quantifies Buffer dependence of Aptamer Binding". Angew. Chem. Int. Ed. 49 (12): 2238–41. doi:10.1002/anie.200903998Joan Miller (ophthalmologist) (2,896 words) [view diff] exact match in snippet view article
VEGF-neutralizing antibody fragment (ranibizumab), and a VEGF-neutralizing aptamer EYE001 (later known as pegaptanib). These studies not only reinforced VEGF'sThrombin (2,932 words) [view diff] case mismatch in snippet view article find links to article
STRUCTURE OF ALPHA-THROMBIN INHIBITED BY A 15-MER SINGLE-STRANDED DNA APTAMER 1hxe: SERINE PROTEASE 1hxf: HUMAN THROMBIN COMPLEX WITH HIRUDIN VARIANTSmall interfering RNA (6,760 words) [view diff] exact match in snippet view article find links to article
circulating half-life. However recently a large Phase III trial of PEGylated RNA aptamer against factor IX had to be discontinued by Regado Biosciences becauseGene targeting (4,387 words) [view diff] exact match in snippet view article find links to article
FEMS Yeast Research. 17 (4). doi:10.1093/femsyr/fox041. PMID 28633406. "Aptamer-guided gene targeting in yeast and human cells". academic.oup.com. RetrievedModified-release dosage (3,252 words) [view diff] exact match in snippet view article find links to article
Benjamin D. (2019). "Biologically Inspired, Cell-Selective Release of Aptamer-Trapped Growth Factors by Traction Forces". Advanced Materials. 31 (7):Janice Limson (1,099 words) [view diff] exact match in snippet view article find links to article
of Electrode Pretreatment Create Misleading Responses in Impedimetric Aptamer Biosensors". ACS Omega. 4 (3). American Chemical Society (ACS): 5839–5847Expanded genetic code (9,128 words) [view diff] exact match in snippet view article find links to article
pair to DNA aptamer generation by in vitro selection (SELEX) and demonstrated the genetic alphabet expansion significantly augment DNA aptamer affinitiesTenascin C (2,565 words) [view diff] exact match in snippet view article find links to article
Daniels DA, Chen H, Hicke BJ, Swiderek KM, Gold L (2003). "A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponentialSomaLogic (1,312 words) [view diff] exact match in snippet view article find links to article
number had increased to about 4,200. The platform is based on modified-aptamer binding technology (“SOMAmers”) that bind to their respective target proteinsToehold mediated strand displacement (989 words) [view diff] exact match in snippet view article find links to article
Carothers, James M. "Multi-state design of kinetically-controlled RNA aptamer ribosensors" (PDF). bioRxiv. bioRxiv. Retrieved 30 October 2018. YurkeNanosensor (6,123 words) [view diff] exact match in snippet view article find links to article
thrombin detection in presence of high concentration of albumin using an aptamer-functionalized nanoporous membrane, Biosensors and Bioelectronics, VolumePPIB (2,598 words) [view diff] exact match in snippet view article find links to article
RR (May 2012). "Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker"Anodic aluminium oxide (1,017 words) [view diff] exact match in snippet view article find links to article
thrombin detection in presence of high concentration of albumin using an aptamer-functionalized nanoporous membrane". Biosensors and Bioelectronics. 126:Platinum nanoparticle (5,347 words) [view diff] exact match in snippet view article find links to article
S (2009). "Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA–PEG nanoparticles". Yearbook of UrologyAli Khademhosseini (2,457 words) [view diff] exact match in snippet view article find links to article
Pribpandao; Alhadrami, Hani A.; Li, Ronald A.; Dokmeci, Mehmet R. (2016-10-04). "Aptamer-Based Microfluidic Electrochemical Biosensor for Monitoring Cell-SecretedRNA interference (15,447 words) [view diff] exact match in snippet view article find links to article
delivery through siRNA conjugates (e.g., GalNAc, carbohydrates, peptides, aptamers, antibodies). Therapeutics using siRNA conjugates have been developed forNatural computing (5,144 words) [view diff] exact match in snippet view article find links to article
26 (2003), 15440-15445. Sazani, P., Larralde, R., Szostak, J. A small aptamer with strong and specific recognition of the triphosphate of ATP. JournalWearable technology (11,969 words) [view diff] exact match in snippet view article find links to article
Janet; Andrews, Anne M.; Emaminejad, Sam (7 January 2022). "Wearable aptamer-field-effect transistor sensing system for noninvasive cortisol monitoring"RNA silencing (5,479 words) [view diff] exact match in snippet view article find links to article
particle (SNALP) Stable for systemic delivery, broad cell-tye delivery Aptamer Targeting of specific receptors, requires sophisticated screening to developOlga Ornatsky (2,055 words) [view diff] exact match in snippet view article find links to article
nanoparticles for high sensitivity multiparameter single cell analysis Mar 2018 Aptamer-facilitated mass cytometry Feb 2018 Tumor platinum concentrations and pathologicalDance Your Ph.D. (2,451 words) [view diff] exact match in snippet view article find links to article
Melting: A Love Story 2010 Chemistry Maureen McKeague Selection of a DNA Aptamer for Homocysteine using SELEX 2009 Graduate Student Sue Lynn Lau The RoleMethods to investigate protein–protein interactions (4,494 words) [view diff] exact match in snippet view article find links to article
2010). "Optical thermophoresis for quantifying the buffer dependence of aptamer binding". Angewandte Chemie. 49 (12): 2238–41. doi:10.1002/anie.200903998Shimon Slavin (3,929 words) [view diff] exact match in snippet view article find links to article
"Immunomodulatory properties of MSC-derived exosomes armed with high-affinity aptamer toward mylein as a platform for reducing multiple sclerosis clinical score"Protein detection (3,780 words) [view diff] exact match in snippet view article find links to article
Yan; Zhang, Junping; Yan, Hao (2006-08-11). "Self-Assembled Signaling Aptamer DNA Arrays for Protein Detection". Angewandte Chemie International EditionCruciform DNA (3,447 words) [view diff] exact match in snippet view article find links to article
cancer cells by a cruciform DNA nanostructure composed of AS1411 and FOXM1 aptamers". Expert Opinion on Drug Delivery. 15 (11): 1045–1052. doi:10.1080/17425247G-quadruplex (11,903 words) [view diff] exact match in snippet view article find links to article
(23): 7515–22. doi:10.1016/j.bmc.2013.09.036. PMID 24148836. Nanopore and Aptamer Biosensor group{NAB group} G-Quadruplex World – a website to discuss publicationsWilliam N. Rom (2,953 words) [view diff] exact match in snippet view article find links to article
and Brody EN. Unlocking biomarker discovery: Large scale application of aptamer proteomic technology for early detection of lung cancer. PLoS One. 2010;Peptidoglycan recognition protein 1 (6,550 words) [view diff] exact match in snippet view article find links to article
course in ulcerative colitis using stool proteins identified through an aptamer-based screen". Nature Communications. 12 (1): 3989. Bibcode:2021NatCo.Yoshito Kaziro (3,157 words) [view diff] exact match in snippet view article find links to article
Kaziro and his team developed RNA aptamers that inhibited Ras’s interaction with Raf-1’s binding domain due to the aptamer’s high affinity for the Ras-bindingSingle-walled carbon nanohorn (7,074 words) [view diff] exact match in snippet view article find links to article
a Conjugate Composed of Comb-Shaped Polyethylene Glycol and a Peptide Aptamer". Molecular Pharmaceutics. 6 (2): 441–447. doi:10.1021/mp800141v. PMID 19718797Artificial enzyme (12,991 words) [view diff] exact match in snippet view article find links to article
Raanan; Vázquez-González, Margarita; Willner, Itamar (4 August 2021). "Aptamer-Modified Cu 2+ -Functionalized C-Dots: Versatile Means to Improve NanozymeUpconverting nanoparticles (8,663 words) [view diff] exact match in snippet view article find links to article
deposited when a fingertip touches a surface. Also, a cocaine-specific aptamer is developed to identify cocaine-laced fingerprints by the same methodPeptidoglycan recognition protein (11,846 words) [view diff] exact match in snippet view article find links to article
course in ulcerative colitis using stool proteins identified through an aptamer-based screen". Nature Communications. 12 (1): 3989. Bibcode:2021NatCo.Ashutosh Chilkoti (2,716 words) [view diff] exact match in snippet view article find links to article
peptide drug for type 2 diabetes, an enzyme drug used to treat gout and an aptamer drug. Chilkoti has made contributions to biosensors and clinical diagnosticsMicroRNA biosensors (7,155 words) [view diff] exact match in snippet view article find links to article
molecules and have different types, including antibodies, antigens, DNA/RNA, aptamers, enzymes, and MIPs (molecularly imprinted polymers). Transducer: following