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searching for Peptidomimetic 32 found (59 total)

Inogatran (92 words) [view diff] exact match in snippet view article find links to article

Inogatran (INN) is a low molecular weight peptidomimetic thrombin inhibitor. Inogatran was developed for the potential treatment of arterial and venous

Danoprevir (487 words) [view diff] exact match in snippet view article find links to article

Danoprevir (INN) is an orally available 15-membered macrocyclic peptidomimetic inhibitor of NS3/4A HCV protease. It contains acylsulfonamide, fluoroisoindole

Farnesyltransferase inhibitor (1,079 words) [view diff] exact match in snippet view article find links to article

sc-221632 FTase Inhibitor I is a potent, cell-permeable, selective, peptidomimetic inhibitor of farnesyltransferase (FTase). 149759-96-6 FTase Inhibitor

Petasis reaction (3,232 words) [view diff] no match in snippet view article find links to article

The Petasis reaction (alternatively called the Petasis borono–Mannich (PBM) reaction) is the multi-component reaction of an amine, a carbonyl, and a vinyl-

HLA-DRB3 (1,108 words) [view diff] case mismatch in snippet view article find links to article

STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDOMIMETIC AND SEB 1d6e: CRYSTAL STRUCTURE OF HLA-DR4 COMPLEX WITH PEPTIDOMIMETIC AND SEB 1j8h: Crystal Structure

FBXL2 (950 words) [view diff] exact match in snippet view article find links to article

membranes via geranylgeranylation, and is sensitive to GGTi-2418 (a CaaX peptidomimetic geranylgeranylation inhibitor that reached clinical trials). The degradation

HLA-DRB1 (688 words) [view diff] case mismatch in snippet view article find links to article

STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDOMIMETIC AND SEB 1d6e: CRYSTAL STRUCTURE OF HLA-DR4 COMPLEX WITH PEPTIDOMIMETIC AND SEB 1dlh: CRYSTAL STRUCTURE

Protein phosphatase 2 (853 words) [view diff] exact match in snippet view article find links to article

catalytically required manganese ions and the dark gray compound at center is a peptidomimetic toxin, microcystin, occupying the active site. From PDB: 2IAE. Identifiers

HLA-DRA (1,145 words) [view diff] case mismatch in snippet view article find links to article

STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDOMIMETIC AND SEB 1d6e: CRYSTAL STRUCTURE OF HLA-DR4 COMPLEX WITH PEPTIDOMIMETIC AND SEB 1dlh: CRYSTAL STRUCTURE

Tropomyosin receptor kinase C (3,936 words) [view diff] exact match in snippet view article find links to article

MAPK8IP3/JIP3 Neurotrophin-3 TβRII DOK5 BMPRII PLCG1 Small molecules peptidomimetics based on β-turn NT-3, with the rationale of targeting the extracellular

Melanocyte-inhibiting factor (1,892 words) [view diff] exact match in snippet view article find links to article

human dopamine receptor subtypes by L-prolyl-L-leucyl-glycinamide and a peptidomimetic analog" (PDF). The Journal of Pharmacology and Experimental Therapeutics

Peptide transporter 1 (935 words) [view diff] exact match in snippet view article find links to article

proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs. Peptide transporter 1 functions in nutrient and drug transport

Inhibitor of apoptosis (1,524 words) [view diff] exact match in snippet view article find links to article

of peptidomimetics whose structure is based on the AVPI tetrapeptide IAP binding motif present in the N-terminus of mature Smac. These peptidomimetic compounds

Ibutamoren (1,269 words) [view diff] exact match in snippet view article find links to article

Howard AD, Feighner SD, Cheng K, Hickey GJ, et al. (October 1997). "Peptidomimetic regulation of growth hormone secretion". Endocrine Reviews. 18 (5).

Cathepsin K (1,710 words) [view diff] case mismatch in snippet view article find links to article

STRUCTURE OF CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT PEPTIDOMIMETIC INHIBITOR 1by8: THE CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN K 1mem:

Factor XI (2,024 words) [view diff] exact match in snippet view article find links to article

of the Catalytic Domain of Coagulation Factor XI in complex with a peptidomimetic Inhibitor 1zpb: Crystal Structure of the Catalytic Domain of Coagulation

CCK-4 (897 words) [view diff] exact match in snippet view article find links to article

CCK2 ligands in their receptor, and contribution to the development of peptidomimetic or non-peptide CCK2 ligands". European Journal of Medicinal Chemistry

Transcytosis (2,229 words) [view diff] exact match in snippet view article find links to article

transporter protein. The transporter protein may be an endogenous peptide, or peptidomimetic monoclonal antibody, which undergoes RMT across the BBB via transport

Creative Biolabs (951 words) [view diff] exact match in snippet view article find links to article

Scaffold for Improving Immunoglobulin-Binding Affinities of Peptide and Peptidomimetic Ligands". Bioconjugate Chemistry. 25 (8): 1479–1491. doi:10.1021/bc500226j

FNTB (868 words) [view diff] case mismatch in snippet view article find links to article

PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYL DIPHOSPHATE AND THE PEPTIDOMIMETIC INHIBITOR L-739,750 1jcr: CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE

Beta-secretase 1 (2,036 words) [view diff] exact match in snippet view article find links to article

inhibitor (2) 2iqg: Crystal Structure of Hydroxyethyl Secondary Amine-based Peptidomimetic Inhibitor of Human Beta-Secretase (BACE) 2irz: Crystal structure of

Jerini (556 words) [view diff] exact match in snippet view article find links to article

peptide drug lead structures and systematically transform them into peptidomimetic (injectable) and small-molecule (oral) drugs, depending on the indication

Ribonucleotide reductase (3,493 words) [view diff] exact match in snippet view article find links to article

Spencer B, Imesch P, Garneau M, Déziel R (May 1996). "Evaluation of a peptidomimetic ribonucleotide reductase inhibitor with a murine model of herpes simplex

Branched-chain amino acid aminotransferase (3,560 words) [view diff] exact match in snippet view article find links to article

used to create unnatural amino acids, important building blocks for peptidomimetic drugs and agricultural products. BCAT from E. coli is typically engineered

FNTA (1,005 words) [view diff] case mismatch in snippet view article find links to article

PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYL DIPHOSPHATE AND THE PEPTIDOMIMETIC INHIBITOR L-739,750 1jcr: CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE

Caspase 3 (3,392 words) [view diff] case mismatch in snippet view article find links to article

CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A 5,6,7 TRICYCLIC PEPTIDOMIMETIC INHIBITOR 2c1e: CRYSTAL STRUCTURES OF CASPASE-3 IN COMPLEX WITH AZA-PEPTIDE

Hanoch Senderowitz (1,507 words) [view diff] exact match in snippet view article find links to article

Edith; Gruzman, Arie (2018). "Structurally Simple, Readily Available Peptidomimetic 1-Benzyl-5-methyl-4-(n-octylamino)pyrimidin-2(1H)-one Exhibited Efficient

PELP-1 (3,909 words) [view diff] exact match in snippet view article find links to article

MM, Butler L, Tilley WD, Hsieh JT, Ahn JM, Raj GV (1 January 2013). "Peptidomimetic targeting of critical androgen receptor-coregulator interactions in

Ester H. Segal (2,159 words) [view diff] exact match in snippet view article find links to article

Ester (2015-10-26). "Optical biosensors for bacteria detection by a peptidomimetic antimicrobial compound". Analyst. 140 (22): 7726–7733. Bibcode:2015Ana

Hilal Lashuel (1,649 words) [view diff] exact match in snippet view article find links to article

(2000-06-01). "Protofilaments, Filaments, Ribbons, and Fibrils from Peptidomimetic Self-Assembly: Implications for Amyloid Fibril Formation and Materials

Simnotrelvir/ritonavir (332 words) [view diff] exact match in snippet view article find links to article

Xiong M, Su H, et al. (May 2023). "Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease". International

Metalloprotease inhibitor (3,897 words) [view diff] exact match in snippet view article find links to article

Collagen-based, peptidomimetic hydroxamates