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searching for Senolytic 13 found (51 total)

alternate case: senolytic

Laura Niedernhofer (1,677 words) [view diff] exact match in snippet view article find links to article

(2015). "The Achilles' heel of senescent cells: From transcriptome to senolytic drugs". Aging Cell. 14 (4): 644–658. doi:10.1111/acel.12344. PMC 4531078

Genetics of aging (2,249 words) [view diff] exact match in snippet view article find links to article

Kirkland in collaboration with Scripps and other groups demonstrated that senolytics, drugs that target senescent cells, enhance cardiac function and improve

Laura Deming (749 words) [view diff] exact match in snippet view article find links to article

Longevity Fund investments include Unity Biotechnology, which develops senolytic drugs targeting diseases of aging, Navitor Pharmaceuticals, and Metacrine

Urokinase receptor (1,151 words) [view diff] exact match in snippet view article find links to article

hdl:10044/1/80980. PMID 32601490. Amor C, Feucht J, Lowe SW (2020). "Senolytic CAR T cells reverse senescence-associated pathologies". Nature. 583 (7814):

Insilico Medicine (1,681 words) [view diff] exact match in snippet view article find links to article

2022.914017. ISSN 1663-4365. PMC 9273868. PMID 35837482. Fouad Sabry, Senolytic: Selectively induce death of senescent cells to improve humans' health

Dasatinib (1,994 words) [view diff] exact match in snippet view article find links to article

"Dasanix". Medex. Retrieved 19 May 2021. Kirkland JL, Tchkonia T (2020). "Senolytic drugs: from discovery to translation". Journal of Internal Medicine. 288

University of Minnesota Medical School (2,319 words) [view diff] exact match in snippet view article find links to article

diseases and conditions. Led by Laura Niedernhofer, this group works on Senolytic Drugs as a potential therapeutic approach to lessen the impacts of aging

Disease-modifying osteoarthritis drug (2,374 words) [view diff] exact match in snippet view article find links to article

Clinical Outcomes Following Single-Dose IA Administration of UBX0101, a Senolytic MDM2/p53 Interaction Inhibitor, in Patients with Knee OA". ACR Meeting

EF-24 (307 words) [view diff] exact match in snippet view article find links to article

Zheng G, Zhou D (January 2019). "The curcumin analog EF24 is a novel senolytic agent". Aging. 11 (2): 771–782. doi:10.18632/aging.101787. PMC 6366974

Α-Ketoglutaric acid (5,510 words) [view diff] exact match in snippet view article find links to article

Kim J, Trott DW, Holland WL, Donato AJ, Lesniewski LA (February 2023). "Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation

GDF11 (3,974 words) [view diff] exact match in snippet view article find links to article

humans—is unclear and continues to be researched. GDF11 is a powerful senolytic and antioxidant. GDF11 fed mice saw 45.7% reduction in senescent liver

MTOR (12,654 words) [view diff] exact match in snippet view article find links to article

Santarelli L, et al. (2018). "Inducers of Senescence, Toxic Compounds, and Senolytics: The Multiple Faces of Nrf2-Activating Phytochemicals in Cancer Adjuvant

Extracellular vesicle (7,002 words) [view diff] exact match in snippet view article find links to article

vascular endothelial inflammation and promote atherosclerosis. EVs also have senolytic potential. EVs harvested from cardio-sphere-derived cells in young rats