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searching for Adaptive immune system 96 found (272 total)

alternate case: adaptive immune system

Receptor editing (283 words) [view diff] exact match in snippet view article find links to article

occurs during the maturation of B cells, which are part of the adaptive immune system. This process forms part of central tolerance to attempt to change
Severe combined immunodeficiency (non-human) (1,417 words) [view diff] exact match in snippet view article
disorder that is characterized by the complete inability of the adaptive immune system to mount, coordinate, and sustain an appropriate immune response
Giardiasis (5,525 words) [view diff] no match in snippet view article find links to article
Giardiasis is a parasitic disease caused by Giardia duodenalis (also known as G. lamblia and G. intestinalis). Infected individuals who experience symptoms
Phase variation (1,657 words) [view diff] exact match in snippet view article find links to article
one type of flagellin, or if a previous encounter has left the adaptive immune system ready to deal with one type of flagellin, switching types renders
CRISPR RNA (1,147 words) [view diff] exact match in snippet view article find links to article
interspaced short palindromic repeats - CRISPR associated systems) is an adaptive immune system found in bacteria and archaea to protect against mobile genetic
Susumu Tonegawa (1,595 words) [view diff] exact match in snippet view article find links to article
Tonegawa's Nobel Prize work elucidated the genetic mechanism of the adaptive immune system, which had been the central question of immunology for over 100
Type I hypersensitivity (840 words) [view diff] case mismatch in snippet view article find links to article
(1–2): 43–49. doi:10.1016/S0300-483X(00)00400-5. PMID 11164991. "The Adaptive Immune System: Type I Immediate Hypersensitivity". Archived from the original
Tulane University School of Medicine (1,956 words) [view diff] exact match in snippet view article find links to article
monumental achievement that provided the organizing principle of the adaptive immune system and launched the course of modern immunology Harold Cummins, M.D
Haematopoietic system (1,197 words) [view diff] exact match in snippet view article find links to article
rate of erythropoiesis. Lymphocytes are the cornerstone of the adaptive immune system. They are derived from common lymphoid progenitors. The lymphoid
Robert D. Schreiber (822 words) [view diff] exact match in snippet view article find links to article
paper, Stutman tested whether athymic, nude mice which lack an adaptive immune system have an increased incidence of tumors. His finding that the incidence
Cas9 (5,610 words) [view diff] exact match in snippet view article find links to article
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) adaptive immune system in Streptococcus pyogenes. S. pyogenes utilizes CRISPR to memorize
Urticarial vasculitis (715 words) [view diff] exact match in snippet view article find links to article
system – the innate immune system: a broad defence system; and the adaptive immune system: the strong immune response capable of remembering previous infections
Survivin (8,387 words) [view diff] no match in snippet view article find links to article
Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. Survivin
Immunopathology (1,245 words) [view diff] exact match in snippet view article find links to article
considered nonspecific. It is usually a more immediate response than the adaptive immune system, usually responding within minutes to hours. It is composed of physical
Streptamer (613 words) [view diff] exact match in snippet view article find links to article
and basic T-cell research. T cells play an important role in the adaptive immune system. They are capable of orchestrating, regulating and coordinating
Ectopic thymus (1,054 words) [view diff] exact match in snippet view article find links to article
likely be left to involute. Given the thymus's role in the body's adaptive immune system, it should be confirmed that the patient has a mediastinal thymus
Animal virus (1,972 words) [view diff] exact match in snippet view article find links to article
Invertebrates do not produce antibodies by the lymphocyte-based adaptive immune system that is central to vertebrate immunity, but they are capable of
Cancer cell (1,920 words) [view diff] case mismatch in snippet view article find links to article
doi:10.3389/fgene.2022.831620. PMC 8895043. PMID 35251135. The Adaptive Immune System: Ways That Antibodies Help to Defend the Body - Antibody-Dependent
Non-peptidic antigen (303 words) [view diff] exact match in snippet view article find links to article
Antigen recognition by human γδ T cells: pattern recognition by the adaptive immune system. Springer Semin Immunopathol. 2000;22:191-217. PMID 11116953 Eberl
Non-peptidic antigen (303 words) [view diff] exact match in snippet view article find links to article
Antigen recognition by human γδ T cells: pattern recognition by the adaptive immune system. Springer Semin Immunopathol. 2000;22:191-217. PMID 11116953 Eberl
Northwest Biotherapeutics (1,097 words) [view diff] exact match in snippet view article find links to article
Dr. Ralph Steinman, dendritic cells act as the general for the adaptive immune system. They educate and direct T-Cells and other immune system cells to
Outline of medicine (2,060 words) [view diff] exact match in snippet view article find links to article
Immunology – study of the immune system, which includes the innate and adaptive immune system in humans, for example. Laboratory medical biology Microbiology
HIV vaccine development (5,600 words) [view diff] exact match in snippet view article find links to article
vaccine would be available within two years. However, priming the adaptive immune system to recognize the viral envelope proteins did not prevent HIV acquisition
Abscopal effect (1,126 words) [view diff] exact match in snippet view article find links to article
mediated by the immune system. Here, local radiation causes tumor cell death, which is followed by adaptive immune system recognition, not unlike a vaccine.
CD79A (2,457 words) [view diff] exact match in snippet view article find links to article
Flajnik MF, Kasahara M (Jan 2010). "Origin and evolution of the adaptive immune system: genetic events and selective pressures". Nature Reviews Genetics
Animal testing on invertebrates (899 words) [view diff] exact match in snippet view article find links to article
development of nerves to be studied in detail. However, the lack of an adaptive immune system and the simplicity of its organs prevent C. elegans from being used
Jan Klein (4,880 words) [view diff] exact match in snippet view article find links to article
textbook sections emphasizing the importance of the so-called non-adaptive immune system (NAIS; he preferred to call it non-anticipatory). He also gave immunology
Jacques Miller (1,197 words) [view diff] exact match in snippet view article find links to article
demonstrating that the thymus is vital for development and function of the adaptive immune system. Prior to this, the thymus was believed to be a vestigial organ
Severe combined immunodeficient mice (1,209 words) [view diff] exact match in snippet view article find links to article
that some mice with SCIDs do in fact have a somewhat functional adaptive immune system. There are many types of SCID mice used by researchers at present
Autoimmune disease in women (5,184 words) [view diff] exact match in snippet view article find links to article
of human biology, including the development and response of the adaptive immune system. Sex hormones such as estrogen, progesterone, and testosterone are
Skin sloughing (1,135 words) [view diff] exact match in snippet view article find links to article
proliferation.[citation needed] Generally, psoriasis affects innate and adaptive immune system cells. Cells that are impacted in psoriasis include dendritic cells
Retinal gene therapy using lentiviral vectors (1,503 words) [view diff] exact match in snippet view article find links to article
them falling under either activity by the innate immune system or adaptive immune system. In the cases of some HIV-1-derived lentiviral vectors, both immune
Neuroimmune system (3,180 words) [view diff] exact match in snippet view article find links to article
involved in neurogenesis. Studies have shown that during times of adaptive immune system response, hippocampal neurogenesis is increased, and conversely
Lasker Award (1,545 words) [view diff] exact match in snippet view article find links to article
monumental achievement that provided the organizing principle of the adaptive immune system and launched the course of modern immunology. Jacques Miller Clinical
Sequence homology (4,179 words) [view diff] exact match in snippet view article find links to article
"Comparative genomics of the MHC: glimpses into the evolution of the adaptive immune system". Immunity. 15 (3): 351–62. doi:10.1016/S1074-7613(01)00198-4. PMID 11567626
Ellen Heber-Katz (1,532 words) [view diff] exact match in snippet view article find links to article
fundamental understanding of how ‘foreign’ antigens activate the adaptive immune system in mammals. In 1976, Heber-Katz was appointed as the Assistant Professor
Phosphoinositide 3-kinase (3,463 words) [view diff] exact match in snippet view article find links to article
and it has been suggested that it evolved in parallel with the adaptive immune system. The regulatory p101 and catalytic p110γ subunits comprise the class
Jeffrey I. Gordon (1,583 words) [view diff] exact match in snippet view article find links to article
habitat. This approach has been extended to describe the role of the adaptive immune system in maintaining the host-microbial relationship. Gordon is the lead
Margaret Ackerman (632 words) [view diff] exact match in snippet view article find links to article
early response system that protects us from pathogens until our adaptive immune system responds. The ability of antibodies to recruit an innate immune
TRPV2 (2,668 words) [view diff] exact match in snippet view article find links to article
where T cells mature. T cells are an important component to the adaptive immune system, because it is where the body adapts to foreign substances; this
Katherine Belov (1,331 words) [view diff] exact match in snippet view article find links to article
Genetics, genomics, marsupial and monotreme genomics, evolution of the adaptive immune system Notable works Genetics of Tasmanian devil facial tumor disease
STAT2 (3,269 words) [view diff] exact match in snippet view article find links to article
for patients with STAT2 deficiency during childhood, until their adaptive immune system has sufficiently developed. From the age 5 years, the frequency
Heterosis (4,524 words) [view diff] exact match in snippet view article find links to article
each parent, which are used in antigen presentation as part of the adaptive immune system. Each different copy of the genes is able to bind and present a
2R hypothesis (2,193 words) [view diff] exact match in snippet view article find links to article
"Comparative genomics of the MHC: glimpses into the evolution of the adaptive immune system". Immunity. 15 (3): 351–62. doi:10.1016/S1074-7613(01)00198-4. PMID 11567626
Pre-metastatic niche (1,586 words) [view diff] exact match in snippet view article find links to article
by the tumor, can protect the cancer cells from detection by the adaptive immune system, which would otherwise be halting metastasis. Myeloid progenitor
Network of Cancer Genes (1,570 words) [view diff] exact match in snippet view article find links to article
Mamie Z.; Haigis, Kevin M.; Elledge, Stephen J. (2021-09-17). "The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation"
Guide RNA (3,624 words) [view diff] exact match in snippet view article find links to article
short palindromic repeats) and its associated Cas enzymes, as their adaptive immune system. When prokaryotes are infected by phages, and manage to fend off
T cell receptor revision (1,333 words) [view diff] exact match in snippet view article find links to article
generating much higher T cell plasticity in the development of the adaptive immune system than we have previously anticipated. Activation-dependent T cell
EF-Tu receptor (1,511 words) [view diff] exact match in snippet view article find links to article
immune cells that can travel this way. Plants also do not have an adaptive immune system, so other forms of immunity are required. One is the use of pattern-recognition
Colostrum (6,258 words) [view diff] exact match in snippet view article find links to article
such as IgA, IgG, and IgM. These are some of the components of the adaptive immune system. Other immune components of colostrum include the major components
CRISPR interference (2,898 words) [view diff] exact match in snippet view article find links to article
genes on the mRNA level. Many bacteria and most archaea have an adaptive immune system which incorporates CRISPR RNA (crRNA) and CRISPR-associated (cas)
Adenosine A2A receptor (5,102 words) [view diff] exact match in snippet view article find links to article
A2A receptor has also been shown to play a regulatory role in the adaptive immune system. In this role, it functions similarly to programmed cell death-1
Medicine (9,777 words) [view diff] exact match in snippet view article find links to article
is the study of the immune system, which includes the innate and adaptive immune system in humans, for example. Lifestyle medicine is the study of the chronic
Heat shock protein (5,525 words) [view diff] exact match in snippet view article find links to article
"Functions of heat shock proteins in pathways of the innate and adaptive immune system". Journal of Immunology. 193 (12): 5765–5771. doi:10.4049/jimmunol
RNA interference (15,445 words) [view diff] exact match in snippet view article find links to article
divided into two separate branches: the innate immune system and the adaptive immune system. The innate immune system is the first defense against infection
Matthew Tirrell (1,264 words) [view diff] exact match in snippet view article find links to article
to diagnose and treat atherosclerosis, and also to stimulate the adaptive immune system to generate desired B-cell and T-cell responses. The other principal
HFE H63D gene mutation (2,646 words) [view diff] exact match in snippet view article find links to article
autoimmune reactions, including periods of decreased defense of the adaptive immune system. Fibrosis in various organ systems, including the skin. Impaired
Pattern recognition receptor (5,164 words) [view diff] exact match in snippet view article find links to article
innate immune system while NBS-LRR proteins are initiated in the adaptive immune system called the Effector-Triggered Immunity. PRRs commonly associate
MHC restriction (2,243 words) [view diff] exact match in snippet view article find links to article
Martin F.; Kasahara, Masanori (2010). "Origin and evolution of the adaptive immune system: genetic events and selective pressures". Nature Reviews Genetics
List of primary immunodeficiencies (1,809 words) [view diff] exact match in snippet view article find links to article
Otulipenia/ORAS The complement system is part of the innate as well as the adaptive immune system; it is a group of circulating proteins that can bind pathogens and
Plant disease epidemiology (2,362 words) [view diff] exact match in snippet view article find links to article
move and fight foreign organisms and they do not have a somatic adaptive immune system, they do have and depend on innate immunity of each cell and on
Reactive oxygen species (8,480 words) [view diff] exact match in snippet view article find links to article
platelets to sites of injury. These also provide a link to the adaptive immune system via the recruitment of leukocytes.[citation needed] Reactive oxygen
Cd1-restricted T cell (1,585 words) [view diff] exact match in snippet view article find links to article
generated by somatic DNA rearrangement, a hallmark of cells of the adaptive immune system. A hallmark of NKT cells is their capacity to rapidly produce copious
DNA vaccine (8,381 words) [view diff] exact match in snippet view article find links to article
and uptake into target cells. The innate system works with the adaptive immune system to mount a response against the DNA encoded protein. CpG-S sequences
Genome evolution in seadragons (1,798 words) [view diff] exact match in snippet view article find links to article
immunologic tolerance in embryos, before they develop their own adaptive immune system. The most recently discovered species is the ruby seadragon, whose
Heinz Wiendl (1,863 words) [view diff] exact match in snippet view article find links to article
H, Schwab N (2018) Sex bias in MHC I-associated shaping of the adaptive immune system. Proc Natl Acad Sci U S A 115(9):2168-2173. Gerwien H*, Hermann
Macrophage (10,188 words) [view diff] exact match in snippet view article find links to article
cells, which serves as an important source of IFN-γ before the adaptive immune system is activated. IFN-γ enhances the innate immune response by inducing
CRISPR gene editing (17,439 words) [view diff] exact match in snippet view article find links to article
Danisco France SAS displayed experimentally how CRISPR systems are an adaptive immune system, and integrate new phage DNA into the CRISPR array, which is how
Glossary of biology (11,418 words) [view diff] exact match in snippet view article find links to article
links B cell A type of lymphocyte in the humoral immunity of the adaptive immune system. bacteria An enormous and diverse clade of microscopic, prokaryotic
Altered Schaedler flora (2,578 words) [view diff] exact match in snippet view article find links to article
signaling. In another study, the innate detection system generates adaptive immune system to maintain intestinal homeostasis. Geuking, et al. examined the
Morphine (13,643 words) [view diff] exact match in snippet view article find links to article
proliferation, growth, and differentiation of T-cells (another cell of the adaptive immune system) and less interleukin-10 (IL-10), a cytokine responsible for promoting
Blood transfusion (12,325 words) [view diff] exact match in snippet view article find links to article
are fully associated with blood transfusion and the innate and adaptive immune system. Allogeneic blood transfusion, through five major mechanisms including
Arsenic biochemistry (5,315 words) [view diff] exact match in snippet view article find links to article
mechanism. Arsenic is highly detrimental to the innate and the adaptive immune system of the body. When the amount of unfolded and misfolded proteins
K. Christopher Garcia (2,278 words) [view diff] exact match in snippet view article find links to article
proving that CD47-based therapy relies upon stimulation of the adaptive immune system. Garcia's lab published the creation of an "orthogonal" IL-2 receptor
Sankar Ghosh (2,448 words) [view diff] exact match in snippet view article find links to article
identification and characterization of signaling intermediates in innate and adaptive immune system, and identification and characterization of a subset of Toll-like
Lynn Corcoran (758 words) [view diff] exact match in snippet view article find links to article
interested in the biology of B lymphocytes, effector cells of the adaptive immune system. They are generated in bone marrow, migrate to the periphery, and
Genetic engineering techniques (6,741 words) [view diff] exact match in snippet view article find links to article
repeat / CRISPR associated protein) systems that function as an adaptive immune system in bacteria and archaea. The CRISPR/Cas system allows bacteria and
Agent-based model (9,159 words) [view diff] exact match in snippet view article find links to article
example, in a study about CD4+ T cells (a key cell type in the adaptive immune system), the researchers modelled biological phenomena occurring at different
Toll-like receptor 4 (9,082 words) [view diff] exact match in snippet view article find links to article
cytokine storms. The impact of TLR4 activation on the innate and adaptive immune system explains why TLR4 agonists, such as LPS derivatives, have been developed
Dennis Kasper (1,434 words) [view diff] exact match in snippet view article find links to article
2011). "A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design". Nature Medicine. 17 (12):
Ozone (18,051 words) [view diff] exact match in snippet view article find links to article
ability to clear bacteria appears impaired by exposure to ozone. The adaptive immune system is the branch of immunity that provides long-term protection via
Non-specific effect of vaccines (6,056 words) [view diff] exact match in snippet view article find links to article
pathogens (trained innate immunity). In SCID mice that have no adaptive immune system, BCG reduced mortality from an otherwise lethal candida infection
CGAS–STING cytosolic DNA sensing pathway (2,880 words) [view diff] exact match in snippet view article find links to article
dendritic cells (DCs). DCs link the innate immune system with the adaptive immune system through phagocytosis and MHC presentation of foreign antigen. The
CRISPR (16,244 words) [view diff] exact match in snippet view article find links to article
immunity. In 2007, the first experimental evidence that CRISPR was an adaptive immune system was published. A CRISPR region in Streptococcus thermophilus acquired
CGAS–STING cytosolic DNA sensing pathway (2,880 words) [view diff] exact match in snippet view article find links to article
dendritic cells (DCs). DCs link the innate immune system with the adaptive immune system through phagocytosis and MHC presentation of foreign antigen. The
Eftilagimod alpha (2,722 words) [view diff] exact match in snippet view article find links to article
with INSERM and Merck Serono, to elucidate LAG-3’s role in the adaptive immune system. Triebel et al. had successfully produced a soluble LAG-3Ig fusion
Proteasome (12,671 words) [view diff] exact match in snippet view article find links to article
plays a straightforward but critical role in the function of the adaptive immune system. Peptide antigens are displayed by the major histocompatibility
CRISPR-Display (2,133 words) [view diff] exact match in snippet view article find links to article
of Technology (MIT), USA. The CRISPR/Cas9 system is based on an adaptive immune system of prokaryotic organisms, and its use for genome editing was first
Intelligent design (19,837 words) [view diff] exact match in snippet view article find links to article
flagellum of E. coli, the blood clotting cascade, cilia, and the adaptive immune system. Critics point out that the irreducible complexity argument assumes
Animal testing (19,523 words) [view diff] exact match in snippet view article find links to article
large numbers may be housed and studied. However, the lack of an adaptive immune system and their simple organs prevent worms from being used in several
Ronald J. Falk (3,648 words) [view diff] exact match in snippet view article find links to article
observations reveal interactions between restricted MPO epitopes and the adaptive immune system within ANCA vasculitis that may inform new antigen-specific therapies
Autism therapies (18,880 words) [view diff] exact match in snippet view article find links to article
promise as treatment for the disorder. Changes in the innate and adaptive immune system have been observed- those with autism show an imbalance in CD3+
Off-target genome editing (6,822 words) [view diff] exact match in snippet view article find links to article
increasingly precise and predictable. The CRISPR-Cas9 system works as the adaptive immune system in bacteria and archaea. When a virus infects the bacteria, this
Genome-wide CRISPR-Cas9 knockout screens (6,164 words) [view diff] exact match in snippet view article find links to article
[citation needed] Since initial identification as a prokaryotic adaptive immune system, the bacterial type II clustered regularly interspaced short palindrome
Manyuan Long (2,811 words) [view diff] case mismatch in snippet view article find links to article
Dating Reveals an Early and Rapid Evolutionary Construction of the Adaptive Immune System". Genome Biology and Evolution. 15 (5). doi:10.1093/gbe/evad081
De novo gene birth (13,534 words) [view diff] exact match in snippet view article find links to article
PMID 30065088. Bekpen C, Xie C, Tautz D (August 2018). "Dealing with the adaptive immune system during de novo evolution of genes from intergenic sequences". BMC