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searching for Axonal transport 107 found (139 total)

Neurophysins (457 words) [view diff] exact match in snippet view article find links to article

located in the posterior pituitary gland aid in intra-axonal transport. During intra-axonal transport, the neurophysin's are believed to prevent the bound

KIF1A (5,565 words) [view diff] exact match in snippet view article find links to article

expressed abundantly in neurons, suggesting its role in axons as an axonal transport motor. To further elucidate the function of KIF1A, in vivo studies

DCTN1 (1,632 words) [view diff] exact match in snippet view article find links to article

Fuchs E, Yang Y (October 2003). "BPAG1n4 is essential for retrograde axonal transport in sensory neurons". The Journal of Cell Biology. 163 (2): 223–9. doi:10

TRAK1 (678 words) [view diff] exact match in snippet view article find links to article

anterograde axonal transport of mitochondrion axonal transport of mitochondrion dendrite morphogenesis positive regulation of axonogenesis anterograde axonal transport

MFN2 (3,260 words) [view diff] exact match in snippet view article find links to article

There is evidence suggesting that it could be due to defects in the axonal transport of mitochondria. Increasing evidence suggests a possible link between

Dystonin (1,485 words) [view diff] exact match in snippet view article find links to article

Delcroix JD, et al. (October 2003). "BPAG1n4 is essential for retrograde axonal transport in sensory neurons". The Journal of Cell Biology. 163 (2): 223–9. doi:10

Neurofilament light polypeptide (2,153 words) [view diff] exact match in snippet view article find links to article

positive regulation of axonogenesis MAPK cascade anterograde axonal transport axonal transport of mitochondrion regulation of axon diameter peripheral nervous

TRAK2 (695 words) [view diff] exact match in snippet view article find links to article

anterograde axonal transport protein localization neurogenesis vesicle transport along microtubule mitochondrion distribution anterograde axonal transport of mitochondrion

SYBU (483 words) [view diff] exact match in snippet view article find links to article

Sheng ZH (2007). "Syntabulin-kinesin-1 family member 5B-mediated axonal transport contributes to activity-dependent presynaptic assembly". J. Neurosci

AP3S1 (462 words) [view diff] exact match in snippet view article find links to article

cytoplasmic vesicle axon cytoplasm Biological process anterograde axonal transport protein transport insulin receptor signaling pathway anterograde synaptic

Spastin (1,032 words) [view diff] exact match in snippet view article find links to article

organization microtubule severing anterograde axonal transport mitotic spindle disassembly axonal transport of mitochondrion membrane fission endoplasmic

AP3B2 (505 words) [view diff] exact match in snippet view article find links to article

Golgi apparatus intracellular vesicle Biological process anterograde axonal transport protein transport anterograde synaptic vesicle transport intracellular

Tetanus toxin (2,359 words) [view diff] exact match in snippet view article find links to article

nerve trunks and into the central nervous system (CNS) by retrograde axonal transport by using dyneins. The tetanus toxin protein has a molecular weight

KLC2 (969 words) [view diff] exact match in snippet view article find links to article

McGrail M, Gindhart JG, Goldstein LS (Nov 2000). "Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein". Cell. 103 (4): 583–94

Pathophysiology of nerve entrapment (4,337 words) [view diff] exact match in snippet view article find links to article

and retrograde axonal transport is impaired. Between 30-50mmHg there will usually be changes in intraneural blood flow, axonal transport, and vascular

Dysbindin (766 words) [view diff] exact match in snippet view article find links to article

neurotransmitter secretion blood coagulation organelle organization anterograde axonal transport melanosome organization positive regulation of gene expression anterograde

Intracellular transport (1,474 words) [view diff] exact match in snippet view article find links to article

aggregates to form. Growing evidence supports the concept that deficits in axonal transport contributes to pathogenesis in multiple neurodegenerative diseases

SNAPAP (1,230 words) [view diff] exact match in snippet view article find links to article

synaptic vesicle fusion to presynaptic active zone membrane anterograde axonal transport melanosome organization autophagosome maturation synaptic vesicle transport

Ronald Vale (2,215 words) [view diff] exact match in snippet view article find links to article

moved in the opposite direction. The results of Vale and colleagues on axonal transport were published in five papers in 1985. Vale did not finish his MD,

Autophagosome (851 words) [view diff] exact match in snippet view article find links to article

(acidify) as they travel towards the cell body along the axon. This axonal transport is disrupted if huntingtin or its interacting partner HAP1, which colocalize

MAPK8IP3 (1,260 words) [view diff] exact match in snippet view article find links to article

M; Gindhart J G; Goldstein L S (November 2000). "Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein". Cell. 103 (4). UNITED

DYNLT1 (855 words) [view diff] exact match in snippet view article find links to article

"Receptor (CD155)-dependent endocytosis of poliovirus and retrograde axonal transport of the endosome". J. Virol. 78 (13): 7186–98. doi:10.1128/JVI.78.13

Sunday Driver (band) (332 words) [view diff] exact match in snippet view article

; Goldstein, Lawrence S.B. (November 10, 2000). "Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein". Cell. 103 (4): 583–94

KLC1 (1,142 words) [view diff] exact match in snippet view article find links to article

McGrail M, Gindhart JG, Goldstein LS (Jan 2001). "Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein". Cell. 103 (4): 583–94

Erika Holzbaur (808 words) [view diff] exact match in snippet view article find links to article

degeneration of motor neurons. Holzbaur has used her understanding of axonal transport to better understand neurodegenerative disease, including Parkinson's

AP3B1 (989 words) [view diff] exact match in snippet view article find links to article

antigen processing and presentation blood coagulation anterograde axonal transport anterograde synaptic vesicle transport transport synaptic vesicle budding

DYNC1H1 (1,152 words) [view diff] exact match in snippet view article find links to article

cycle transport positive regulation of cold-induced thermogenesis mitotic cell cycle nuclear migration retrograde axonal transport Sources:Amigo / QuickGO

AP3D1 (951 words) [view diff] exact match in snippet view article find links to article

processing and presentation eye pigment biosynthetic process anterograde axonal transport melanosome organization synaptic vesicle membrane organization endosome

AP3M1 (860 words) [view diff] exact match in snippet view article find links to article

clathrin adaptor complex axon cytoplasm Biological process anterograde axonal transport protein transport anterograde synaptic vesicle transport protein targeting

ITM2B (715 words) [view diff] exact match in snippet view article find links to article

PMID 14586629. S2CID 20479606. Choi SI, Vidal R, Frangione B, Levy E (2004). "Axonal transport of British and Danish amyloid peptides via secretory vesicles". FASEB

KIF1B (1,040 words) [view diff] exact match in snippet view article find links to article

intracellular transport neuron-neuron synaptic transmission anterograde axonal transport microtubule-based movement neuromuscular synaptic transmission mitochondrion

Hexane-2,5-dione (333 words) [view diff] exact match in snippet view article find links to article

causes cross-linking and denaturation of proteins, which perturbs axonal transport and function and causes damage to nerve cells. 2,5-Hexanedione has

KIF4A (1,061 words) [view diff] exact match in snippet view article find links to article

midzone assembly mitotic cytokinesis organelle organization anterograde axonal transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

KIF5A (990 words) [view diff] exact match in snippet view article find links to article

Alzheimer's disease by modulating the toxic effect of beta-amyloid on axonal transport of mitochondria. GRCh38: Ensembl release 89: ENSG00000155980 – Ensembl

KIF3B (1,377 words) [view diff] exact match in snippet view article find links to article

antigen via MHC class II mitotic spindle organization anterograde axonal transport positive regulation of cytokinesis mitotic spindle assembly determination

Motor protein (1,538 words) [view diff] exact match in snippet view article find links to article

cytoplasmic dyneins play essential roles in intracellular transport such as axonal transport and in the formation of the spindle apparatus and the separation of

BLOC1S2 (561 words) [view diff] exact match in snippet view article find links to article

Biological process platelet dense granule organization anterograde axonal transport positive regulation of transcription, DNA-templated melanosome organization

SOD1 (3,629 words) [view diff] exact match in snippet view article find links to article

activity response to heat response to organic substance anterograde axonal transport spermatogenesis response to ethanol neurofilament cytoskeleton organization

Copeptin (1,760 words) [view diff] exact match in snippet view article find links to article

neurons of the hypothalamus and in the supraoptic nucleus. During axonal transport, pre-pro-AVP is proteolytically cleaved into vasopressin, neurophysin

ARL8A (249 words) [view diff] exact match in snippet view article find links to article

signal transduction cell cycle chromosome segregation neutrophil degranulation anterograde axonal transport protein transport Sources:Amigo / QuickGO

Poliovirus (5,732 words) [view diff] exact match in snippet view article find links to article

muscle tissue, to the spinal cord through nerve pathways via retrograde axonal transport. A third hypothesis is that the virus is imported into the CNS via

Hashimoto's encephalopathy (1,651 words) [view diff] exact match in snippet view article find links to article

An additional feature of a low-energy state is failure to maintain axonal transport via dynein/kinesin ATPases, which in many diseases results in neuronal

Actin related protein 10 homolog (75 words) [view diff] exact match in snippet view article find links to article

antigen processing and presentation of exogenous peptide antigen via MHC class II retrograde axonal transport of mitochondrion Sources:Amigo / QuickGO

BLOC1S1 (525 words) [view diff] exact match in snippet view article find links to article

Biological process platelet dense granule organization anterograde axonal transport endosomal transport melanosome organization aerobic respiration anterograde

Paracytophagy (2,434 words) [view diff] exact match in snippet view article find links to article

second mechanism of reaching the brain tissue is achieved through intra-axonal transport. In this mechanism, Listeria travels along the nerves to the brain

Emetine (1,019 words) [view diff] exact match in snippet view article find links to article

Koyuncu OO, Wirblich C, Schnell MJ, Enquist LW (July 2018). "Retrograde axonal transport of rabies virus is unaffected by interferon treatment but blocked by

RAB21 (514 words) [view diff] exact match in snippet view article find links to article

receptor-mediated endocytosis regulation of axon extension anterograde axonal transport regulation of exocytosis positive regulation of dendrite morphogenesis

Dynamin-like 120 kDa protein (1,957 words) [view diff] exact match in snippet view article find links to article

organization positive regulation of dendrite development cellular senescence axonal transport of mitochondrion positive regulation of mitochondrial fusion positive

KIF3A (1,113 words) [view diff] exact match in snippet view article find links to article

involved in cilium assembly cilium assembly axon guidance anterograde axonal transport protein transport protein localization to cell junction Sources:Amigo

ARL8B (569 words) [view diff] exact match in snippet view article find links to article

GTPase mediated signal transduction cell division cell cycle lysosome localization anterograde axonal transport protein transport Sources:Amigo / QuickGO

Campenot chamber (941 words) [view diff] exact match in snippet view article find links to article

amyloid beta. A modified 2-chamber system was used to examine the axonal transport of herpes simplex virus by examining the transmission of the virus

ALS (14,009 words) [view diff] exact match in snippet view article find links to article

in ALS that are important for maintaining the cytoskeleton and for axonal transport include DCTN1, PFN1, and TUBA4A. There are a number of ALS genes that

Malapterurus electricus (555 words) [view diff] exact match in snippet view article find links to article

of Malapterurus have been used in studies of neuronal metabolism, axonal transport. In their natural habitat they form pairs and lay their eggs in excavated

Dynactin (2,815 words) [view diff] exact match in snippet view article find links to article

interaction between cytoplasmic dynein and dynactin is required for fast axonal transport". Proceedings of the National Academy of Sciences of the United States

Ubiquitin carboxy-terminal hydrolase L1 (2,637 words) [view diff] exact match in snippet view article find links to article

axonogenesis ubiquitin-dependent protein catabolic process proteolysis axonal transport of mitochondrion response to ischemia neuromuscular process negative

PLDN (826 words) [view diff] exact match in snippet view article find links to article

melanosome transport endosome to melanosome transport anterograde axonal transport neuron projection development anterograde synaptic vesicle transport

Thomas Schwarz (164 words) [view diff] case mismatch in snippet view article find links to article

Górska-Andrzejak; Ian A. Meinertzhagen; Thomas L. Schwarz (12 December 2002). "Axonal Transport of Mitochondria to Synapses Depends on Milton, a Novel Drosophila Protein"

MUTED (572 words) [view diff] exact match in snippet view article find links to article

synaptic vesicle transport endosome to melanosome transport anterograde axonal transport melanosome organization positive regulation of pigment cell differentiation

Neurohypophysial hormone (545 words) [view diff] exact match in snippet view article find links to article

1197. PMID 11427695. Jones CW, Pickering BT (December 1972). "Intra-axonal transport and turnover of neurohypophysial hormones in the rat". J. Physiol.

Molecular biophysics (2,012 words) [view diff] exact match in snippet view article find links to article

cytoplasmic dyneins play essential roles in intracellular transport such as axonal transport and in the formation of the spindle apparatus and the separation of

CNO (gene) (568 words) [view diff] exact match in snippet view article

cytosol BLOC-1 complex axon cytoplasm Biological process anterograde axonal transport melanosome organization intracellular transport anterograde synaptic

CLSTN1 (720 words) [view diff] exact match in snippet view article find links to article

Francis PT, Noble W, Miller CC (Jul 2012). "Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production". Human

Zucapsaicin (1,666 words) [view diff] exact match in snippet view article find links to article

desensitization is related to capsaicin's ability to block the intra-axonal transport of NGF, SP and somatostatin. The desensitization is a reversible phenomenon

PAFAH1B1 (1,514 words) [view diff] exact match in snippet view article find links to article

development brain morphogenesis chemical synaptic transmission retrograde axonal transport cell differentiation negative regulation of neuron projection development

Daniel Carleton Gajdusek (1,764 words) [view diff] exact match in snippet view article find links to article

Gajdusek, Daniel Carleton (1985). "Hypothesis: interference with axonal transport of neurofilament as a common pathogenetic mechanism in certain diseases

Broad Institute (2,604 words) [view diff] exact match in snippet view article find links to article

Cell and Regenerative Biology Sam Peng is a chemist who researches axonal transport in neurons and the molecular dynamics of dynein motors. William Sellers

FEZ1 (1,052 words) [view diff] exact match in snippet view article find links to article

establishment of cell polarity positive regulation of anterograde axonal transport of mitochondrion mitochondrion morphogenesis Sources:Amigo / QuickGO

Paraplegin (1,256 words) [view diff] exact match in snippet view article find links to article

mitochondrial outer membrane permeabilization involved in programmed cell death mitochondrion organization anterograde axonal transport Sources:Amigo / QuickGO

Transcytosis (2,229 words) [view diff] exact match in snippet view article find links to article

1041200208. PMID 6430919. S2CID 24779404. Fabian, R. H. (1991). "Retrograde axonal transport and transcytosis of immunoglobulins: Implications for the pathogenesis

Node of Ranvier (3,281 words) [view diff] exact match in snippet view article find links to article

increased at the nodes, which suggest that there is a bottleneck of axonal transport in both directions as well as local axonal-glial signaling. When a

Herpes simplex research (8,434 words) [view diff] exact match in snippet view article find links to article

native replication in epithelial cells but are incapable of retrograde axonal transport and invasion of the nervous system. A single dose of the R2 vaccine

Rabies virus (4,259 words) [view diff] exact match in snippet view article find links to article

the neural pathways of the peripheral nervous system. The retrograde axonal transport of Rabies lyssavirus to the central nervous system (CNS) is the key

Ian Meinertzhagen (342 words) [view diff] case mismatch in snippet view article find links to article

Jolanta Górska-Andrzejak, Ian A. Meinertzhagen, Thomas L. Schwarz "Axonal Transport of Mitochondria to Synapses Depends on Milton, a Novel Drosophila Protein"

APLP2 (1,460 words) [view diff] exact match in snippet view article find links to article

maintenance of synapses. APLP2 has shown to act as a cargo receptor in axonal transport for intact proteins. APLP2 is part of a family of mammalian membrane

Xiang-Lei Yang (2,698 words) [view diff] exact match in snippet view article find links to article

Zhao X, Liu H, et al. Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy. Nat Commun. 2018;9(1):1007

Sperm-associated antigen 9 (1,287 words) [view diff] exact match in snippet view article find links to article

McGrail M, Gindhart JG, Goldstein LS (Nov 2000). "Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein". Cell. 103 (4): 583–94

Xiang-Lei Yang (2,698 words) [view diff] exact match in snippet view article find links to article

Zhao X, Liu H, et al. Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy. Nat Commun. 2018;9(1):1007

Bernice Shanet (1,074 words) [view diff] exact match in snippet view article find links to article

the regenerating goldfish visual system, with a continuing focus on axonal transport and the role it plays in defining the process of regeneration. Throughout

Charles Philippe Leblond (3,208 words) [view diff] exact match in snippet view article find links to article

published days after the Watson and Crick Nature article, the discovery of axonal transport, the Warshawsky et al. finding that nascent proteins are processed

FMR1 (3,455 words) [view diff] exact match in snippet view article find links to article

protein phosphorylation central nervous system development anterograde axonal transport negative regulation of translation regulation of dendrite morphogenesis

Protein kinase R (4,105 words) [view diff] exact match in snippet view article find links to article

accelerated endocytosis, endosome swelling and selectively impaired axonal transport of Rab5 endosomes. PKR and Tau phosphorylation It is reported earlier

Glyceraldehyde 3-phosphate dehydrogenase (3,750 words) [view diff] exact match in snippet view article find links to article

(January 2013). "Vesicular glycolysis provides on-board energy for fast axonal transport". Cell. 152 (3): 479–491. doi:10.1016/j.cell.2012.12.029. PMID 23374344

Nobutaka Hirokawa (680 words) [view diff] exact match in snippet view article find links to article

superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors. Cell 81(5): 769-780, 1995. Hirokawa

Atg1 (1,464 words) [view diff] exact match in snippet view article find links to article

H, Flores R, et al. (December 2008). "UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly". Genes Dev. 22 (23): 3292–307. doi:10

Hypothalamic–pituitary–adrenal axis (5,906 words) [view diff] exact match in snippet view article find links to article

system of the hypophyseal stalk and vasopressin is transported by axonal transport to the posterior pituitary gland. There, CRH and vasopressin act synergistically

Mitogen-activated protein kinase (5,501 words) [view diff] exact match in snippet view article find links to article

(Jan 2008). ""JIP"ing along the axon: the complex roles of JIPs in axonal transport". BioEssays. 30 (1): 10–4. doi:10.1002/bies.20695. PMID 18081006. Nihalani

End-plate potential (2,775 words) [view diff] exact match in snippet view article find links to article

created in the cell body of the neuron and then transported via fast axonal transport down to the axon terminal. Small clear core vesicles transport small

HSPA8 (3,533 words) [view diff] exact match in snippet view article find links to article

vesicle-mediated transport cytokine-mediated signaling pathway cellular response to heat Unfolded Protein Response slow axonal transport Sources:Amigo / QuickGO

Epigenetic regulation of neurogenesis (5,725 words) [view diff] exact match in snippet view article find links to article

deacetylases HDAC6 and Sirt2 through knockdown processes rescued both axonal transport and locomotor behavior. This further connects to the common mechanisms

HIF1A (6,534 words) [view diff] exact match in snippet view article find links to article

DNA-templated positive regulation of transcription, DNA-templated axonal transport of mitochondrion positive regulation of macroautophagy cartilage development

PINK1 (2,677 words) [view diff] exact match in snippet view article find links to article

"Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria". PLOS Genetics. 8 (3): e102537. doi:10.1371/journal

Mitophagy (4,131 words) [view diff] exact match in snippet view article find links to article

PMID 37748140. Saxton, William M.; Hollenbeck, Peter J. (2012). "The axonal transport of mitochondria". Journal of Cell Science. 125 (9): 2095–2104. doi:10

Carpal tunnel syndrome (9,447 words) [view diff] exact match in snippet view article find links to article

is the double crush syndrome, where compression may interfere with axonal transport, and two separate points of compression (e.g. neck and wrist), neither

NDEL1 (2,014 words) [view diff] exact match in snippet view article find links to article

growth cone centrosome kinesin complex Biological process retrograde axonal transport cell differentiation activation of GTPase activity chromosome segregation

Alzheimer's disease (18,882 words) [view diff] exact match in snippet view article find links to article

(February 2008). "Neurotrophic factors in Alzheimer's disease: role of axonal transport". Genes, Brain and Behavior. 7 (Suppl 1): 43–56. doi:10.1111/j.1601-183X

West Caucasian bat lyssavirus (1,897 words) [view diff] exact match in snippet view article find links to article

can eventually travel to the central nervous system (CNS) via the axonal transport system. At that point, it is possible to see clinical signs, such as

Telomeric repeat-binding factor 2 (3,340 words) [view diff] exact match in snippet view article find links to article

telomere regulation of transcription by RNA polymerase II anterograde axonal transport of messenger ribonucleoprotein complex Sources:Amigo / QuickGO

CASS4 (3,332 words) [view diff] exact match in snippet view article find links to article

function of CASS4, it has been speculated that it may have a role in axonal transport and influence the expression of the amyloid precursor protein (APP)

Discodermolide (3,460 words) [view diff] exact match in snippet view article find links to article

tauopathy, (+)-discodermolide stabilizes microtubules and restores fast axonal transport in cells, offsetting the loss of function caused by aggregation of

AVP gene (2,611 words) [view diff] exact match in snippet view article find links to article

"Neurophysin biosynthesis: conversion of a putative precursor during axonal transport". Science. 195 (4284): 1354–6. Bibcode:1977Sci...195.1354G. doi:10

Biochemistry of Alzheimer's disease (7,749 words) [view diff] exact match in snippet view article find links to article

Deshpande A, Yu C, Jungbauer L, et al. (April 2009). "Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta". Proceedings

SGK1 (4,213 words) [view diff] exact match in snippet view article find links to article

Saudou F, Villard L (Feb 2012). "Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway". Neurobiology of Disease. 45 (2):

Genetics of amyotrophic lateral sclerosis (3,945 words) [view diff] exact match in snippet view article find links to article

neurotrophic signaling is lost, with defective anterograde and retrograde axonal transport observed in early pathogenesis, and (4) free radical-mediated oxidative

Terence S. Dermody (1,794 words) [view diff] exact match in snippet view article find links to article

(February 2020). "Reovirus uses macropinocytosis-mediated entry and fast axonal transport to infect neurons". PLOS Pathogens. 16 (2): e1008380. doi:10.1371/journal

Hereditary sensory and autonomic neuropathy type I (5,140 words) [view diff] exact match in snippet view article find links to article

signaling is involved in axon guidance and synapse formation, as well as axonal transport and the organization of the microtubule network in developing neurons

Neuronal self-avoidance (5,788 words) [view diff] exact match in snippet view article find links to article

as the diffusion of cytoplasmic signals either passively or by fast axonal transport". In the late 1990s and beyond, model organisms started to be used

List of women neuroscientists (8,913 words) [view diff] exact match in snippet view article find links to article

Koushika (fl. from 2000s), neuroscientist focusing on regulation of axonal transport within nerve cells Vijayalakshmi Ravindranath (born 1953), neuroscientist