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searching for Cell cycle checkpoint 57 found (90 total)

RAD1 homolog (1,652 words) [view diff] exact match in snippet view article find links to article

Cell cycle checkpoint protein RAD1 is a protein that in humans is encoded by the RAD1 gene. This gene encodes a component of a heterotrimeric cell cycle

CHEK1 (3,340 words) [view diff] exact match in snippet view article find links to article

CHEK1 gene. Chk1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response. Activation of Chk1 results in the initiation of cell cycle

DNAJC7 (614 words) [view diff] no match in snippet view article find links to article

domain of Tpr2 regulates its interaction with the proapoptotic and cell-cycle checkpoint protein, Rad9". Biochem. Biophys. Res. Commun. 287 (4): 932–40.

TLX1 (1,104 words) [view diff] no match in snippet view article find links to article

interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615): 454–8. Bibcode:1997Natur.385..454K. doi:10

Protein BTG2 (3,182 words) [view diff] exact match in snippet view article find links to article

particular, the BTG2 protein has been shown to negatively control a cell cycle checkpoint at the G1 to S phase transition in fibroblasts and neuronal cells

Ribosomal protein S6 (378 words) [view diff] exact match in snippet view article find links to article

rRNA processing activation-induced cell death of T cells mitotic cell cycle checkpoint signaling gastrulation mammalian oogenesis stage T cell differentiation

DCLRE1B (734 words) [view diff] exact match in snippet view article find links to article

cytoskeleton nucleus nucleoplasm nuclear body Biological process cell cycle checkpoint signaling protection from non-homologous end joining at telomere

RRM2B (1,504 words) [view diff] no match in snippet view article find links to article

2000). "A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage". Nature. 404 (6773): 42–9. Bibcode:2000Natur.404

60S ribosomal protein L24 (752 words) [view diff] exact match in snippet view article find links to article

large subunit precursor of preribosome viral transcription mitotic cell cycle checkpoint signaling exit from mitosis SRP-dependent cotranslational protein

RI-1 (chemical) (280 words) [view diff] exact match in snippet view article

participates in DNA damage induction and complex signal pathway of cell cycle checkpoint of homologous recombination in cells. However, over-expression of

Replication factor C (866 words) [view diff] exact match in snippet view article find links to article

backup factor for DNA polymerases. RFC2 gene product required for a cell cycle checkpoint. RFC is a heteropentamer in budding yeast, it is encoded either

Tax gene product (682 words) [view diff] exact match in snippet view article find links to article

proteins are involved in these processes, including cyclins and cell cycle checkpoint proteins (p53 and Rb). Interesting, HTLV-1 Tax viral gene is known

TTK (gene) (836 words) [view diff] exact match in snippet view article

population proliferation protein phosphorylation phosphorylation mitotic cell cycle checkpoint signaling peptidyl-tyrosine phosphorylation female meiosis chromosome

PLK2 (745 words) [view diff] exact match in snippet view article find links to article

process positive regulation of autophagy phosphorylation mitotic cell cycle checkpoint signaling G1 phase mitotic spindle organization Rap protein signal

Nibrin (2,607 words) [view diff] exact match in snippet view article find links to article

NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint control". Cell Res. 16 (1): 45–54. doi:10.1038/sj.cr.7310007. PMID 16467875

Urea transporter 1 (819 words) [view diff] exact match in snippet view article find links to article

(1996). "RACH2, a novel human gene that complements a fission yeast cell cycle checkpoint mutation". Mol. Biol. Cell. 6 (10): 1411–21. doi:10.1091/mbc.6.10

Pancreatic polypeptide receptor 1 (1,017 words) [view diff] no match in snippet view article find links to article

interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615): 454–458. Bibcode:1997Natur.385..454K. doi:10

NSUN2 (424 words) [view diff] exact match in snippet view article find links to article

cytoskeleton nucleus Biological process tRNA methylation meiotic cell cycle checkpoint signaling cell division tRNA modification methylation spermatid

MARK3 (1,217 words) [view diff] exact match in snippet view article find links to article

Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpoint". J. Biol. Chem. 279 (46): 48319–28. doi:10.1074/jbc.M404440200

PLK3 (1,212 words) [view diff] exact match in snippet view article find links to article

signaling phosphorylation response to reactive oxygen species mitotic cell cycle checkpoint signaling mitotic G1/S transition checkpoint signaling positive

Wee1-like protein kinase (1,028 words) [view diff] exact match in snippet view article find links to article

transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle mitotic cell cycle checkpoint signaling Sources:Amigo / QuickGO

INTS3 (443 words) [view diff] exact match in snippet view article find links to article

snRNA processing cellular response to DNA damage stimulus mitotic cell cycle checkpoint signaling snRNA transcription by RNA polymerase II Sources:Amigo

PARP inhibitor (2,052 words) [view diff] exact match in snippet view article find links to article

Q, Pandita RK, Hunt CR, Xiang T, Misri S, et al. (July 2009). "Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells

WNT9A (648 words) [view diff] exact match in snippet view article find links to article

smoothened signaling pathway anatomical structure development mitotic cell cycle checkpoint signaling iris morphogenesis cornea development in camera-type eye

NABP1 (334 words) [view diff] exact match in snippet view article find links to article

repair cellular response to DNA damage stimulus snRNA transcription by RNA polymerase II mitotic cell cycle checkpoint signaling Sources:Amigo / QuickGO

ZWINT (823 words) [view diff] exact match in snippet view article find links to article

Biological process mitotic sister chromatid segregation mitotic cell cycle checkpoint signaling cell division cell cycle establishment of localization

MAD2L1BP (823 words) [view diff] exact match in snippet view article find links to article

nucleus nucleolus nuclear membrane Biological process regulation of exit from mitosis mitotic cell cycle checkpoint signaling Sources:Amigo / QuickGO

MAD1L1 (644 words) [view diff] exact match in snippet view article find links to article

phase transition regulation of metaphase plate congression mitotic cell cycle checkpoint signaling thymus development cell division negative regulation of

Homeobox protein SIX1 (1,387 words) [view diff] exact match in snippet view article find links to article

EA, Mutter GL, Pardee AB (October 1998). "Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of

HRAS (1,338 words) [view diff] exact match in snippet view article find links to article

cell proliferation positive regulation of ruffle assembly mitotic cell cycle checkpoint signaling positive regulation of cell migration ephrin receptor

PPP1CC (1,210 words) [view diff] no match in snippet view article find links to article

interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615). ENGLAND: 454–8. Bibcode:1997Natur.385..454K

PRCC (gene) (756 words) [view diff] exact match in snippet view article

nucleoplasm nuclear speck Biological process cell cycle mitotic cell cycle checkpoint signaling mRNA splicing, via spliceosome Sources:Amigo / QuickGO

PPP2CA (1,716 words) [view diff] no match in snippet view article find links to article

interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615): 454–8. Bibcode:1997Natur.385..454K. doi:10

PPP2CB (1,185 words) [view diff] no match in snippet view article find links to article

interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615): 454–8. Bibcode:1997Natur.385..454K. doi:10

CHFR (930 words) [view diff] exact match in snippet view article find links to article

Cellular component PML body nucleus Biological process mitotic cell cycle checkpoint signaling cell division mitotic cell cycle cell cycle protein polyubiquitination

PPP1CB (1,176 words) [view diff] no match in snippet view article find links to article

interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615): 454–8. Bibcode:1997Natur.385..454K. doi:10

RBBP8 (1,794 words) [view diff] exact match in snippet view article find links to article

functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor

MAD2L1 (1,975 words) [view diff] exact match in snippet view article find links to article

checkpoint negative regulation of protein catabolic process mitotic cell cycle checkpoint signaling negative regulation of apoptotic process cell division

Non-homologous end joining (3,679 words) [view diff] exact match in snippet view article find links to article

and repair deficiency syndromes: Linking genomic instability and cell cycle checkpoint proficiency". DNA Repair (Amst.). 8 (9): 1139–52. doi:10.1016/j

Anaphase lag (1,534 words) [view diff] exact match in snippet view article find links to article

traits such as angiogenesis, immune system evasion, and loss of cell cycle checkpoint genes. Aneuploidy is a drastic divergence from the normal karyotype

TGF beta 1 (2,290 words) [view diff] exact match in snippet view article find links to article

negative regulation of extracellular matrix disassembly mitotic cell cycle checkpoint signaling positive regulation of fibroblast proliferation negative

Protein kinase B (3,754 words) [view diff] exact match in snippet view article find links to article

(November 2002). "Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage". Molecular and Cellular Biology. 22 (22):

AKT1 (2,850 words) [view diff] exact match in snippet view article find links to article

activation-induced cell death of T cells response to heat regulation of cell cycle checkpoint response to organic substance response to insulin-like growth factor

Albert J. Fornace Jr. (1,021 words) [view diff] exact match in snippet view article find links to article

Plunkett, B. S., Vogelstein, B., and Fornace, A. J., Jr. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

BUB1B (2,313 words) [view diff] exact match in snippet view article find links to article

anaphase-promoting complex-dependent catabolic process mitotic cell cycle checkpoint signaling protein phosphorylation metaphase cell cycle apoptotic

BUB1 (2,228 words) [view diff] exact match in snippet view article find links to article

Biological process phosphorylation chromosome segregation mitotic cell cycle checkpoint signaling cell division regulation of chromosome segregation protein

Bcl-2-like protein 1 (2,223 words) [view diff] exact match in snippet view article find links to article

negative regulation of intrinsic apoptotic signaling pathway mitotic cell cycle checkpoint signaling negative regulation of release of cytochrome c from mitochondria

DLG1 (1,961 words) [view diff] exact match in snippet view article find links to article

astral microtubule organization actin filament organization mitotic cell cycle checkpoint signaling receptor clustering establishment or maintenance of cell

MRN complex (3,079 words) [view diff] exact match in snippet view article find links to article

detection is thought to be controlled by both Nbs1 and MRE11. Likewise, cell cycle checkpoint regulation is ultimately controlled by phosphorylation activity

PROX1 (1,103 words) [view diff] exact match in snippet view article find links to article

nutrient levels hepatocyte proliferation positive regulation of cell cycle checkpoint regulation of circadian rhythm circadian rhythm acinar cell differentiation

HERC2 (3,291 words) [view diff] exact match in snippet view article find links to article

mutation. It is involved in coordinating the Chk1-directed DNA damage/cell cycle checkpoint response by regulating the stability of the deubiquitination enzyme

Oncovirus (6,056 words) [view diff] exact match in snippet view article find links to article

essential cell functions, including but not limited to a crucial cell cycle checkpoint, making them a target for viruses attempting to interrupt regular

Schizosaccharomyces pombe (6,047 words) [view diff] no match in snippet view article find links to article

that the cell takes to ensure precise cell division occurs is the cell-cycle checkpoint. These checkpoints ensure any mutagens are eliminated. This is done

Retinoblastoma protein (9,499 words) [view diff] exact match in snippet view article find links to article

activity cell morphogenesis involved in neuron differentiation mitotic cell cycle checkpoint signaling regulation of transcription by RNA polymerase II positive

Neuronal cell cycle (2,128 words) [view diff] exact match in snippet view article find links to article

Disease. J. Neurosci. 23, 2557–2563. Yasutis, K.M., and Kozminski, K.G. (2013). Cell cycle checkpoint regulators reach a zillion. Cell Cycle 12, 1501–1509.

NUMB (gene) (4,144 words) [view diff] exact match in snippet view article

cell leads to a decrease in TP53, causing impaired apoptosis and cell cycle checkpoint response. Restoring Numb levels also restores TP53 expression and

G-quadruplex (11,903 words) [view diff] exact match in snippet view article find links to article

promoter region of this specific pathway. The cyclin-dependent cell cycle checkpoint kinase inhibitor-1 CDKN1A (also known as p21) gene harbours promoter