Find link

language:

Find link is a tool written by Edward Betts.

searching for DNA methyltransferase 101 found (186 total)

DMAP1 (1,090 words) [view diff] exact match in snippet view article find links to article

DNA methyltransferase 1-associated protein 1 is an enzyme that in humans is encoded by the DMAP1 gene. This gene encodes a subunit of several, distinct

Site-specific DNA-methyltransferase (53 words) [view diff] no match in snippet view article find links to article

Site-specific DNA-methyltransferase may refer to: Site-specific DNA-methyltransferase (adenine-specific) Site-specific DNA-methyltransferase (cytosine-N4-specific)

TRDMT1 (727 words) [view diff] exact match in snippet view article find links to article

Medicine. Yoder JA, Bestor TH (Mar 1998). "A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast". Hum Mol Genet. 7 (2): 279–84

DIP2B (239 words) [view diff] exact match in snippet view article find links to article

family, it contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1, as well as AMP-binding sites. The presence

AGT II (313 words) [view diff] exact match in snippet view article find links to article

alkyltransferase, a protein that in humans is encoded by the O6-methylguanine DNA methyltransferase (MGMT) gene. In humans, O6-alkylguanine DNA alkyltransferase preferentially

6-O-Methylguanine (658 words) [view diff] exact match in snippet view article find links to article

6-O-methylguanine in DNA is primarily carried out by O-6-methylguanine-DNA methyltransferase (MGMT). Epigenetic reductions in MGMT expression are one of the

NCAPG (540 words) [view diff] exact match in snippet view article find links to article

Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome

Azacitidine (1,915 words) [view diff] exact match in snippet view article find links to article

antineoplastic activity via two mechanisms – at low doses, by inhibiting of DNA methyltransferase, causing hypomethylation of DNA, and at high doses, by its direct

KIF4A (1,061 words) [view diff] exact match in snippet view article find links to article

Heale JT, et al. (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome

Cancer cell (1,727 words) [view diff] exact match in snippet view article find links to article

O-6-methylguanine-DNA methyltransferase is observed in several different kinds of cancer (see Wikipedia article O-6-methylguanine-DNA methyltransferase). Although

Modification methylase (51 words) [view diff] no match in snippet view article find links to article

methylase may refer to: Site-specific DNA-methyltransferase (adenine-specific) Site-specific DNA-methyltransferase (cytosine-N4-specific) This set index

Iridoviridae (549 words) [view diff] exact match in snippet view article find links to article

25% of their cytosine residues methylated by a virally encoded DNA methyltransferase.[citation needed] Similar to the herpes viruses, transcription occurs

Mir-301 microRNA precursor family (551 words) [view diff] exact match in snippet view article find links to article

Huang N, Patel T (March 2010). "MicroRNA-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human

SMC2 (1,315 words) [view diff] exact match in snippet view article find links to article

Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome

Bernd Kaina (950 words) [view diff] exact match in snippet view article find links to article

chemotherapeutic agents. He identified the repair enzyme O-6-methylguanine-DNA methyltransferase (MGMT) as a protection mechanism against the killing, clastogenic

Ada regulon (1,387 words) [view diff] exact match in snippet view article find links to article

structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coli. EMBO Journal. 13:1495–1501. He C, Wei H, Verdine GL

Immunodeficiency–centromeric instability–facial anomalies syndrome (563 words) [view diff] no match in snippet view article find links to article

this syndrome: Cell division cycle associated protein 7 (CDCA7), DNA-methyltransferase 3b (DNMT3B), Lymphoid specific helicase (HELLS) and Zinc finger-

Organic Lake virophage (253 words) [view diff] exact match in snippet view article find links to article

ATPase, a putative DNA polymerase/primase and a N6 adenine specific DNA methyltransferase.[citation needed] Yau, S.; Lauro, F. M.; Demaere, M. Z.; Brown,

UBE2I (2,840 words) [view diff] exact match in snippet view article find links to article

McNally JG, Karpova T, Robertson KD (2004). "Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases

40S ribosomal protein S8 (719 words) [view diff] exact match in snippet view article find links to article

et al. (2005). "Myc represses transcription through recruitment of DNA methyltransferase corepressor". EMBO J. 24 (2): 336–46. doi:10.1038/sj.emboj.7600509

Plicamycin (484 words) [view diff] exact match in snippet view article find links to article

Lin RK, Hsu CH, Wang YC (November 2007). "Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells". Anti-Cancer Drugs

Temozolomide (2,958 words) [view diff] exact match in snippet view article find links to article

alkyltransferase (AGT) encoded in humans by the O-6-methylguanine-DNA methyltransferase (MGMT) gene. In some tumors, epigenetic silencing of the MGMT gene

H2BFM (121 words) [view diff] exact match in snippet view article find links to article

(December 2005). "Proteomic analysis of human O6-methylguanine-DNA methyltransferase by affinity chromatography and tandem mass spectrometry". Biochemical

Protein inhibitor of activated STAT2 (1,263 words) [view diff] exact match in snippet view article find links to article

McNally JG, Karpova T, Robertson KD (2004). "Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases

Alkylating antineoplastic agent (1,472 words) [view diff] exact match in snippet view article find links to article

when in the presence of the DNA-repair enzyme O-6-methylguanine-DNA methyltransferase (MGMT). Cross-linking of double-stranded DNA by alkylating agents

PIAS1 (1,351 words) [view diff] exact match in snippet view article find links to article

McNally JG, Karpova T, Robertson KD (2004). "Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases

Rudolf Jaenisch (1,017 words) [view diff] exact match in snippet view article find links to article

; Bestor, T. H.; Jaenisch, R. (1992). "Targeted mutation of the DNA methyltransferase gene results in embryonic lethality". Cell. 69 (6): 915–926. doi:10

Autosomal dominant cerebellar ataxia, deafness, and narcolepsy (925 words) [view diff] exact match in snippet view article find links to article

error. This gene plays a role in the production of an enzyme called DNA methyltransferase 1, which is involved in DNA methylation. This enzyme is essential

Neoplasm (5,873 words) [view diff] exact match in snippet view article find links to article

patterns of DNA methylation of the two distinct O6-methylguanine-DNA methyltransferase (O6-MGMT) promoter regions in colorectal cancer". Mol. Biol. Rep

Ada (protein) (288 words) [view diff] exact match in snippet view article

the other for alkylated phosphotriesters. Ogt O-6-methylguanine-DNA methyltransferase Lindahl T, Sedgwick B, Sekiguchi M, Nakabeppu Y (1988). "Regulation

Pseudoceratina (1,378 words) [view diff] case mismatch in snippet view article find links to article

Pseudoceratina purpurea: Inhibition of Both Histone Deacetylase and DNA Methyltransferase". ChemInform. 34 (32). doi:10.1002/chin.200332143. ISSN 0931-7597

Methylation induced premeiotically (168 words) [view diff] case mismatch in snippet view article find links to article

and Development in Ascobolus Reveals a Novel Type of Eukaryotic DNA Methyltransferase Structure". Cell. 91 (2): 281–90. doi:10.1016/S0092-8674(00)80410-9

Ethyl methanesulfonate (1,014 words) [view diff] exact match in snippet view article find links to article

reacting with the active site cysteine of the O-6-methylguanine-DNA methyltransferase repair protein. The in vivo half-life of O6-ethylguanine was reported

Dacarbazine (1,065 words) [view diff] exact match in snippet view article find links to article

Kramm CM, Staege MS (January 2014). "Impact of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and MGMT expression on dacarbazine resistance

SNAP-tag (1,001 words) [view diff] exact match in snippet view article find links to article

mammalian enzyme AGT, encoded in humans by the O-6-methylguanine-DNA methyltransferase (MGMT) gene. SNAP-tag was obtained using a directed evolution strategy

Daniel Hochhauser (471 words) [view diff] case mismatch in snippet view article find links to article

and Colorectal Cancers and Methylation of the O6-Methylguanine-DNA Methyltransferase Promoter". Molecular Cancer Therapeutics. 12 (5): 809–818. doi:10

SMC4 (1,452 words) [view diff] exact match in snippet view article find links to article

Heale JT, et al. (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome

CXXC1 (714 words) [view diff] exact match in snippet view article find links to article

that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1". Mol

Non-small-cell lung cancer (5,301 words) [view diff] exact match in snippet view article find links to article

K, Sidransky D, Ahrendt SA (November 2001). "O(6)-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in

Methyltransferase like 4 (71 words) [view diff] no match in snippet view article find links to article

activity transferase activity nucleic acid binding site-specific DNA-methyltransferase (adenine-specific) activity Cellular component nucleus Biological

DDX20 (1,739 words) [view diff] exact match in snippet view article find links to article

suppressor by controlling NF-κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression". Hepatology. 57 (1): 162–170. doi:10.1002/hep

Déborah Bourc'his (466 words) [view diff] exact match in snippet view article find links to article

Yann; Guillou, Florian; Bourc’his, Déborah (2016-11-18). "The DNA methyltransferase DNMT3C protects male germ cells from transposon activity". Science

Clostridioides difficile (5,742 words) [view diff] exact match in snippet view article find links to article

be significantly reduced after inactivation of C. diffiicile's DNA methyltransferase CamA, raising the prospect of developing a drug that may inhibit

Hiroyuki Sasaki (404 words) [view diff] exact match in snippet view article find links to article

PMID 8469285. Kaneda M; et al. (2004). "Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting". Nature. 429 (6994):

Interleukin 6 (7,497 words) [view diff] exact match in snippet view article find links to article

activated PKB can phosphorylate the nuclear localization signal on DNA methyltransferase-1 (DNMT1). This phosphorylation causes movement of DNMT1 to the

KMT5B (828 words) [view diff] exact match in snippet view article find links to article

human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins"

Chromosome 21 (2,969 words) [view diff] exact match in snippet view article find links to article

interferon-induced GTP-binding protein Mx2 N6AMT1: N-6 adenine-specific DNA methyltransferase 1 NDUFV3: encoding NADH dehydrogenase [ubiquinone] flavoprotein

UHRF1 (1,302 words) [view diff] exact match in snippet view article find links to article

binds to hemi-methylated DNA during S-phase and recruits the main DNA methyltransferase protein, DNMT1, to regulate chromatin structure and gene expression

RECK (950 words) [view diff] exact match in snippet view article find links to article

of the metastasis suppressor RECK by RAS oncogene is mediated by DNA methyltransferase 3b-induced promoter methylation". Cancer Res. 66 (17): 8413–20.

Poly (ADP-ribose) polymerase (3,085 words) [view diff] exact match in snippet view article

ADP-ribose polymers, either free or PARP1 bound, are able to inhibit DNA methyltransferase activity at CpG sites. Thus, CTCF is involved in the cross-talk

SMARCA5 (1,266 words) [view diff] exact match in snippet view article find links to article

Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome

MBD1 (1,240 words) [view diff] exact match in snippet view article find links to article

component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins". Nat Genet. 16 (3): 256–9. doi:10.1038/ng0797-256

Migratory locust (1,628 words) [view diff] exact match in snippet view article find links to article

Pengcheng; Li, Beibei; Lin, Zhe; Kang, Le; Wang, Xianhui (2020). "DNA methyltransferase 3 participates in behavioral phase change in the migratory locust"

ZHX1 (882 words) [view diff] exact match in snippet view article find links to article

et al. (April 2007). "Zinc-fingers and homeoboxes 1 (ZHX1) binds DNA methyltransferase (DNMT) 3B to enhance DNMT3B-mediated transcriptional repression"

Cilengitide (891 words) [view diff] exact match in snippet view article find links to article

with newly diagnosed glioblastoma and methylated O6-methylguanine-DNA methyltransferase (MGMT) gene promoter: Key results of the multicenter, randomized

Antisense RNA (2,995 words) [view diff] exact match in snippet view article find links to article

regulation:' a) AsRNAs can induce DNA methylation by recruiting a DNA methyltransferase (DNMT). b) AsRNAs can induce histone methylation by recruiting of

Field cancerization (1,850 words) [view diff] exact match in snippet view article find links to article

(November 2010). "Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in

Matthias Preusser (583 words) [view diff] exact match in snippet view article find links to article

investigations on the significance of the MGMT gene (O-6-methylguanine-DNA methyltransferase), the IDH gene (glioblastoma multiforme) and the BRAF gene and the

Karen Lillycrop (859 words) [view diff] exact match in snippet view article find links to article

Lillycrop, Karen A., Hanson, Mark A. and Casanello, P. Role of DNA methyltransferase 1 on the altered eNOS expression in human umbilical endothelium

Klotho (biology) (3,786 words) [view diff] exact match in snippet view article

(September 2017). "Immunohistochemical evaluation of Klotho and DNA methyltransferase 3a in oral squamous cell carcinomas". Medical Molecular Morphology

Point mutation (4,359 words) [view diff] exact match in snippet view article find links to article

and development in Ascobolus reveals a novel type of eukaryotic DNA methyltransferase structure". Cell. 91 (2): 281–90. doi:10.1016/S0092-8674(00)80410-9

Luca Regli (942 words) [view diff] case mismatch in snippet view article find links to article

"Clinical Trial Substantiates the Predictive Value of O-6-Methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastoma Patients Treated with Temozolomide"

List of restriction enzyme cutting sites: A (3,038 words) [view diff] exact match in snippet view article find links to article

Kneale G (June 2003). "Purification and characterisation of a novel DNA methyltransferase, M.AhdI". Nucleic Acids Res. 31 (11): 2803–10. doi:10.1093/nar/gkg399

SUMO1 (2,334 words) [view diff] exact match in snippet view article find links to article

PMID 18583933. Kang ES, Park CW, Chung JH (December 2001). "Dnmt3b, de novo DNA methyltransferase, interacts with SUMO-1 and Ubc9 through its N-terminal region and

Optical mapping (2,102 words) [view diff] exact match in snippet view article find links to article

Robert K. (2014-04-01). "Super-resolution optical DNA Mapping via DNA methyltransferase-directed click chemistry". Nucleic Acids Research. 42 (7): e50.

Stanley Michael Gartler (1,710 words) [view diff] exact match in snippet view article find links to article

T. K.; Weemaes, C. M.; Gartler, S. M. (1999-12-07). "The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome". Proceedings

Tatton-Brown–Rahman syndrome (569 words) [view diff] exact match in snippet view article find links to article

Ruark E, Harmer J, Ramsay E, et al. (2014). "Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability"

Contribution of epigenetic modifications to evolution (2,033 words) [view diff] exact match in snippet view article find links to article

demethylation at specific promoters by targeted steric blockage of DNA methyltransferase with CRISPR/dCas9". Nature Communications. 12 (1): 5711. Bibcode:2021NatCo

Myelodysplastic syndrome (6,312 words) [view diff] exact match in snippet view article find links to article

uncontrolled cell growth and cytopenias. The recently approved DNA methyltransferase inhibitors take advantage of this mechanism by creating a more orderly

Malignant transformation (4,027 words) [view diff] exact match in snippet view article find links to article

Zhang W, Lu J, Zhuang Z, Zeng G (2013). "MicroRNA-152 targets DNA methyltransferase 1 in NiS-transformed cells via a feedback mechanism". Carcinogenesis

Epigenetic therapy (5,831 words) [view diff] exact match in snippet view article find links to article

internal dysregulation caused by these epigenetic alterations. DNA methyltransferase inhibitors (DNMTis) are used as a treatment option against various

NOMe-seq (2,009 words) [view diff] exact match in snippet view article find links to article

characterization and expression of the gene coding for a cytosine-5-DNA methyltransferase recognizing GpC". Nucleic Acids Research. 26 (17): 3961–3966. doi:10

Single-molecule real-time sequencing (3,165 words) [view diff] case mismatch in snippet view article find links to article

Clark TA, Murray IA, Morgan RD, et al. (2012). "Characterization of DNA Methyltransferase Specificities Using Single-Molecule, Real-Time DNA Sequencing".

HDAC1 (5,476 words) [view diff] exact match in snippet view article find links to article

Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T (January 2000). "DNA methyltransferase Dnmt1 associates with histone deacetylase activity". Nature Genetics

Margaret Goodell (1,170 words) [view diff] exact match in snippet view article find links to article

self-renewal and activation. She has recently uncovered how the de novo DNA methyltransferase, DNMT3A — one of the most important tumor suppressors in the blood

Glioma (6,374 words) [view diff] exact match in snippet view article find links to article

Buchroithner J, Pichler J, et al. (January 2010). "O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide

List of restriction enzyme cutting sites: Bsa–Bso (1,359 words) [view diff] exact match in snippet view article find links to article

1993). "Cloning, purification and characterization of the BseCI DNA methyltransferase from Bacillus stearothermophilus". Gene. 133 (1): 91–4. doi:10

Myc (6,709 words) [view diff] exact match in snippet view article find links to article

(January 2005). "Myc represses transcription through recruitment of DNA methyltransferase corepressor". The EMBO Journal. 24 (2): 336–46. doi:10.1038/sj.emboj

NDRG1 (2,179 words) [view diff] exact match in snippet view article find links to article

binds and stabilizes methyltransferases, chiefly O-6-methylguanine-DNA methyltransferase (MGMT), a DNA repair protein. Thus, higher expression of NDRG1 can

Epigenetics of anxiety and stress–related disorders (11,227 words) [view diff] exact match in snippet view article find links to article

MeCP2, which as previously mentioned, can be altered by stress. DNA methyltransferase 1 (DNMT1) belongs to a family of proteins known as DNA methyltransferases

Epigenetics of plant growth and development (2,120 words) [view diff] exact match in snippet view article find links to article

KRYPTONITE causes histone H3 lysine 9 dimethylation which recruits the DNA methyltransferase CHROMOMETHTLASE3 in tandem with HETEROCHROMATIN PROTEIN1. This association

Secreted frizzled-related protein 1 (6,317 words) [view diff] exact match in snippet view article find links to article

and converting it to methylcytosine. This process is catalyzed by DNA methyltransferase. In numerous cancers, the CpG islands of selected genes are aberrantly

Arsenic poisoning (9,442 words) [view diff] exact match in snippet view article find links to article

were hyper- and two of them were hypomethylated. Higher levels of DNA methyltransferase mRNA and enzyme activity were found. Kitchin (2001) proposed a model

DNA-3-methyladenine glycosylase (2,589 words) [view diff] exact match in snippet view article find links to article

enzyme that specifically repairs O6MeG damages (O-6-methylguanine-DNA methyltransferase) had a shorter lifespan and aged more rapidly than wild type mice

Antineoplastic resistance (3,900 words) [view diff] exact match in snippet view article find links to article

alkyl group to DNA to stop it from being read. O6-methylguanine DNA methyltransferase (MGMT) is a DNA repair enzyme which removes alkyl groups from DNA

Retinoblastoma protein (9,499 words) [view diff] exact match in snippet view article find links to article

Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T (January 2000). "DNA methyltransferase Dnmt1 associates with histone deacetylase activity". Nature Genetics

Estrogen receptor alpha (6,357 words) [view diff] exact match in snippet view article find links to article

2001). "The modified human DNA repair enzyme O(6)-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription

Transgenerational epigenetic inheritance in plants (2,184 words) [view diff] case mismatch in snippet view article find links to article

methylation patterns in plants: the maintenance of CG by the enzyme MET1 (DNA Methyltransferase 1), the CMT3/SUVH pathway, and the RNA-dependent DNA methylation

Third-generation sequencing (3,988 words) [view diff] exact match in snippet view article find links to article

Roberts, R. J.; Korlach, J. (2012-02-01). "Characterization of DNA methyltransferase specificities using single-molecule, real-time DNA sequencing".

Nutriepigenomics (4,722 words) [view diff] exact match in snippet view article find links to article

protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes

Biomolecular engineering (5,707 words) [view diff] case mismatch in snippet view article find links to article

Huang, N.; Patel, T. (2010). "MicroRNA-Dependent Regulation of DNA Methyltransferase-1 in Human Malignant Cholangiocytes. Hepatology." Hepatology. ppg

MicroRNA (16,586 words) [view diff] exact match in snippet view article find links to article

Buchroithner J, Pichler J, et al. (January 2010). "O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide

Epigenetic clock (6,333 words) [view diff] exact match in snippet view article find links to article

Baylin SB, O'Hagan HM (June 2016). "Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage". Journal of Molecular Cell Biology

Philip Rosenstiel (1,462 words) [view diff] exact match in snippet view article find links to article

Weber-Stiehl, S., Stengel, S. T., Arnold, P., ... & Rosenstiel, P. (2022). DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration

Epigenetics of schizophrenia (5,482 words) [view diff] exact match in snippet view article find links to article

Hajos M, Costa E, Guidotti A (October 2008). "Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation

Epigenetics of depression (4,421 words) [view diff] exact match in snippet view article find links to article

DNA methylation plays a role in depressive behavior, delivery of DNA methyltransferase inhibitors results in a reversal of depression-like behaviors. It

Charles Brenner (biochemist) (3,874 words) [view diff] case mismatch in snippet view article

(2013). "Laccaic Acid A Is a Direct, DNA-competitive Inhibitor of DNA Methyltransferase 1". J. Biol. Chem. 288 (33): 23858–23867. doi:10.1074/jbc.M113.480517

Laccaic acid (1,491 words) [view diff] case mismatch in snippet view article find links to article

2013). "Laccaic Acid A Is a Direct, DNA-competitive Inhibitor of DNA Methyltransferase 1 *". Journal of Biological Chemistry. 288 (33): 23858–23867. doi:10

Management of schizophrenia (9,879 words) [view diff] exact match in snippet view article find links to article

G, Davis JM, Costa E (January 2007). "S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis". NeuroReport. 18 (1): 57–60

Facioscapulohumeral muscular dystrophy (16,337 words) [view diff] exact match in snippet view article find links to article

microphtalmia syndrome. Another cause of FSHD2 is mutation in DNMT3B (DNA methyltransferase 3B). Mutations in DNMT3B can also cause ICF syndrome. As of 2020

Epigenetics of human development (6,145 words) [view diff] exact match in snippet view article find links to article

hemoglobin production. ICF syndrome, caused by a mutation in the DNA methyltransferase 3b gene or DNA hypomethylation, which causes lack of DNA methylation