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ADAM (protein)
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ADAMs (short for a disintegrin and metalloproteinase) are a family of single-pass transmembrane and secreted metalloendopeptidases. All ADAMs are characterizedADAM10 (2,466 words) [view diff] exact match in snippet view article find links to article
A Disintegrin and metalloproteinase domain-containing protein 10, also known as ADAM10 or CDw156 or CD156c is a protein that in humans is encoded by theADAM11 (540 words) [view diff] exact match in snippet view article find links to article
Disintegrin and metalloproteinase domain-containing protein 11 is an enzyme that in humans is encoded by the ADAM11 gene. This gene encodes a member ofADAMTS9 (623 words) [view diff] exact match in snippet view article find links to article
A disintegrin and metalloproteinase with thrombospondin motifs 9 is an enzyme that in humans is encoded by the ADAMTS9 gene. This gene encodes a memberADAM28 (603 words) [view diff] exact match in snippet view article find links to article
Disintegrin and metalloproteinase domain-containing protein 28 is an enzyme that in humans is encoded by the ADAM28 gene. This gene encodes a member ofADAM18 (488 words) [view diff] exact match in snippet view article find links to article
Disintegrin and metalloproteinase domain-containing protein 18 is an enzyme that in humans is encoded by the ADAM18 gene. This gene encodes a member ofADAMTS10 (587 words) [view diff] exact match in snippet view article find links to article
A disintegrin and metalloproteinase with thrombospondin motifs 10 is an enzyme that in humans is encoded by the ADAMTS10 gene. This gene belongs to theADAMTS12 (539 words) [view diff] exact match in snippet view article find links to article
A disintegrin and metalloproteinase with thrombospondin motifs 12 is an enzyme that in humans is encoded by the ADAMTS12 gene. This gene encodes a memberADAM23 (663 words) [view diff] exact match in snippet view article find links to article
Disintegrin and metalloproteinase domain-containing protein 23 is a non-catalytic protein that in humans is encoded by the ADAM23 gene. It is a memberADAM2 (685 words) [view diff] exact match in snippet view article find links to article
Disintegrin and metalloproteinase domain-containing protein 2 or Beta-fertilin is an enzyme that in humans is encoded by the ADAM2 gene. This gene encodesADAM10 endopeptidase (101 words) [view diff] exact match in snippet view article find links to article
ADAM10 endopeptidase (EC 3.4.24.81, Kuzbanian protein, myelin-associated disintegrin metalloproteinase) is an enzyme. This enzyme catalyses the followingADAMTS2 (1,040 words) [view diff] exact match in snippet view article find links to article
A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS2) also known as procollagen I N-proteinase (PC I-NP) is an enzyme that in humansADAMTSL1 (584 words) [view diff] exact match in snippet view article find links to article
gene encodes a secreted protein resembling members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This proteinSNX9 (1,009 words) [view diff] exact match in snippet view article find links to article
cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendageADAMTS14 (148 words) [view diff] exact match in snippet view article find links to article
modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual membersMAD2L2 (1,003 words) [view diff] exact match in snippet view article find links to article
metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 withUpshaw–Schulman syndrome (3,483 words) [view diff] exact match in snippet view article find links to article
affections are not seldom measurable (such as ECG changes). The ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motif 13) gene is locatedMAD2L1 (1,975 words) [view diff] exact match in snippet view article find links to article
metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 withADAMTS17 (727 words) [view diff] exact match in snippet view article find links to article
encoded by the ADAMTS17 gene. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTSReticulate acropigmentation of Kitamura (168 words) [view diff] exact match in snippet view article find links to article
occurs elsewhere. This condition is associated with mutations in the a disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) gene. ThisChromosome 21 (2,969 words) [view diff] exact match in snippet view article find links to article
ADAMTS1 encoding enzyme a disintegrin and metalloproteinase with thrombospondin motifs 1 ADAMTS5: encoding enzyme a disintegrin and metalloproteinase withADAMDEC1 (415 words) [view diff] exact match in snippet view article find links to article
encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during the maturationApadamtase alfa (492 words) [view diff] exact match in snippet view article find links to article
thrombotic thrombocytopenic purpura. Apadamtase alfa is a human recombinant a disintegrin and metalloproteinase with thrombospondin motifs 13. It is given by injectionCXCL16 (433 words) [view diff] exact match in snippet view article find links to article
is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10". J Immunol. 172 (10): 6362–72. doi:10ADAMTS6 (392 words) [view diff] exact match in snippet view article find links to article
encoded by the ADAMTS6 gene. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. MembersUniGene (1,265 words) [view diff] exact match in snippet view article find links to article
entitled ‘‘A disintegrin and metalloprotease domain 10’’ that contains the sequence for human ADAM10 can be retrieved by entering ADAM10, disintegrin, AF009615Jararhagin (215 words) [view diff] exact match in snippet view article find links to article
metalloprotease, jararhagin, from Bothrops jararaca venom. Insights into the disintegrin gene family". The Journal of Biological Chemistry. 267 (32): 22869–76PAPLN (320 words) [view diff] exact match in snippet view article find links to article
doi:10.1242/dev.127.24.5475. PMID 11076767. Apte SS (November 2009). "A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1Hennekam syndrome (473 words) [view diff] exact match in snippet view article find links to article
Tvorogov D, et al. (February 2014). "CCBE1 Enhances Lymphangiogenesis via A Disintegrin and Metalloprotease With Thrombospondin Motifs-3–Mediated Vascular EndothelialMucrolysin (146 words) [view diff] exact match in snippet view article find links to article
Zinc metalloproteinase/disintegrin Identifiers Organism Protobothrops mucrosquamatus Symbol ? UniProt O57413Triptolide (919 words) [view diff] exact match in snippet view article find links to article
Sayat, G. S. Robertson, P. A. Marignani,Triptolide: An inhibitor of a disintegrin and metalloproteinase 10 (ADAM10) in cancer cells. Cancer Biol Ther 2009Adamalysin (119 words) [view diff] exact match in snippet view article find links to article
venom of the eastern diamondback rattlesnake (Crotalus adamanteus). A disintegrin and metalloproteinase Kurecki T, Laskowski M, Kress LF (November 1978)Russellysin (225 words) [view diff] exact match in snippet view article find links to article
enzyme from Russell's viper venom (RVV-X). A novel metalloproteinase with disintegrin (platelet aggregation inhibitor)-like and C-type lectin-like domains"List of human clusters of differentiation (467 words) [view diff] exact match in snippet view article find links to article
Disintegrin And Metalloprotease family CD156a Disintegrin and metalloproteinase domain-containing protein 8; encoded by ADAM8 gene CD156b DisintegrinNeuropilin (1,081 words) [view diff] exact match in snippet view article find links to article
Endothelial Growth Factor) Induces NRP1 (Neuropilin-1) Cleavage via ADAMs (a Disintegrin and Metalloproteinase) 9 and 10 to Generate Novel Carboxy-Terminal NRP1Gloydius saxatilis (360 words) [view diff] exact match in snippet view article find links to article
Yoon-Jung Jang, Ok-Hee Jeon, Doo-Sik Kim. 2007. Saxatilin, a Snake Venom Disintegrin, Regulates Platelet Activation Associated with Human Vascular EndothelialNotch proteins (3,548 words) [view diff] exact match in snippet view article find links to article
in the NECD. Enzymatic proteolysis at this site is carried out by a A Disintegrin and Metalloprotease domain (ADAM) family protease. This protein is calledN-Feruloylserotonin (620 words) [view diff] exact match in snippet view article find links to article
can suppress the expression of matrix metalloproteinases MMP3/13 and a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), thus attenuatingVon Willebrand factor (2,121 words) [view diff] exact match in snippet view article find links to article
(catabolism) of VWF is largely mediated by the enzyme ADAMTS13 (acronym of "a disintegrin-like and metalloprotease with thrombospondin type 1 motif no. 13"). ItCCBE1 (702 words) [view diff] exact match in snippet view article find links to article
Terhi; Alitalo, Kari (2014). "CCBE1 Enhances Lymphangiogenesis via A Disintegrin and Metalloprotease With Thrombospondin Motifs-3-Mediated Vascular EndothelialMHC class I polypeptide–related sequence A (1,266 words) [view diff] exact match in snippet view article find links to article
protein by the cooperation of disulfide isomerase (ERp5) and ADAM (a disintegrin and metalloproteinase) and MMP (matrix metalloproteinase) proteases targetingPMEL (gene) (1,534 words) [view diff] exact match in snippet view article
of the furin family, a "sheddase" that might include members of the a disintegrin and metalloproteinase (ADAM) family, and additional proteases in melanosomesVascular endothelial growth factor C (3,104 words) [view diff] exact match in snippet view article find links to article
Holopainen T, et al. (May 2014). "CCBE1 enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelialTIMP1 (1,179 words) [view diff] exact match in snippet view article find links to article
inhibitory molecule that regulates matrix metalloproteinases (MMPs), and disintegrin-metalloproteinases (ADAMs and ADAMTSs). In regulating MMPs, TIMP1 playsGrowth hormone-binding protein (2,797 words) [view diff] exact match in snippet view article find links to article
Johnson RS, Paxton RJ, March CJ, Cerretti DP (1997). "A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells". Nature. 385 (6618):Alain Israël (677 words) [view diff] exact match in snippet view article find links to article
novel proteolytic cleavage involved in Notch signaling : role of the disintegrin-metalloprotease TACE », Mol Cell, (2000), 5(2), p. 207-16 JarriaultEastern copperhead (4,879 words) [view diff] exact match in snippet view article find links to article
Schönthal AH, Chen TC (2005). "The role of contortrostatin, a snake venom disintegrin, in the inhibition of tumor progression and prolongation of survivalIGFBP3 (4,717 words) [view diff] exact match in snippet view article find links to article
Shi Z, Xu W, Loechel F, Wewer UM, Murphy LJ (June 2000). "ADAM 12, a disintegrin metalloprotease, interacts with insulin-like growth factor-binding protein-3"Tumor necrosis factor (6,302 words) [view diff] exact match in snippet view article find links to article
Slack JL, Wolfson MF, et al. (February 1997). "A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells". Nature. 385 (6618):Harald Jockusch (1,026 words) [view diff] exact match in snippet view article find links to article
(TNF-alpha) regulates shedding of TNF-alpha receptor 1 by the metalloprotease-disintegrin ADAM8: evidence for a protease-regulated feedback loop in neuroprotectionSodium channel (5,597 words) [view diff] exact match in snippet view article find links to article
Epidermal growth factor-like (EGF-like) repeats that repel beta2. A disintegrin and metalloproteinase (ADAM) 10 sheds beta 2's ectodomain possibly inducingHanoch Senderowitz (1,507 words) [view diff] exact match in snippet view article find links to article
Eble, Johannes; Marcinkiewicz, Cezary; Lazarovici, Philip (2016). "Disintegrin-Based, Synthetic Cyclic KTS Peptides as Novel Dual Antagonists of α1β1/α2β1PTPRM (6,053 words) [view diff] exact match in snippet view article find links to article
for another RPTP, LAR (or PTPRF). Then PTPmu is likely cleaved by an A disintegrin and metalloproteinase (ADAM) protease in the extracellular domain ofMichael Jeltsch (759 words) [view diff] exact match in snippet view article find links to article
Alitalo, K (19 February 2014). "CCBE1 Enhances Lymphangiogenesis via A Disintegrin and Metalloprotease With Thrombospondin Motifs-3–Mediated Vascular EndothelialNotch signaling pathway (10,149 words) [view diff] exact match in snippet view article find links to article
novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE". Molecular Cell. 5 (2): 207–216. doi:10Tej P. Singh (1,663 words) [view diff] exact match in snippet view article find links to article
Christian; Singh, Tej P. (23 August 2005). "Crystal structure of the disintegrin heterodimer from saw-scaled viper (Echis carinatus) at 1.9 A resolution"Role of microglia in disease (5,051 words) [view diff] exact match in snippet view article find links to article
metalloproteinases MMP-1, MMP-2, MMP-3, and MMP-9, and the metalloprotease-disintegrin ADAM8 (plasminogen) which forms outside microglia and degrades the extracellularVoltage-gated sodium channel (3,587 words) [view diff] exact match in snippet view article find links to article
Epidermal growth factor-like (EGF-like) repeats that repel beta2. A disintegrin and metalloproteinase (ADAM) 10 sheds beta 2's ectodomain possibly inducing