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Longer titles found: Epitope binning (view), Epitope mapping (view), Linear epitope (view), Conformational epitope (view), Immune Epitope Database and Analysis Resource (view), Cryptic self epitopes (view), Neoepitope (view)

searching for Epitope 365 found (610 total)

alternate case: epitope

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carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system. Antibodies raised against the HNK-1 epitope have

recognizing the tumor-specific epitope of mucin-1 (TA-MUC1), enabling it to differentiate between tumor MUC1 and non-tumor MUC1 epitopes. Gatipotuzumab is being

corresponding to amino acids 98-106. HA-tag has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered

HIV IMMUNODOMINANT EPITOPE KM1(LPPVVAKEI) 1e28: NONSTANDARD PEPTIDE BINDING OF HLA-B*5101 COMPLEXED WITH HIV IMMUNODOMINANT EPITOPE KM2(TAFTIPSI) 1eey:

antibody's binding sites (epitopes) on the target protein is referred to as "epitope mapping." Finding the binding epitope of an antibody is essential

Abagovomab is a mouse anti-idiotype monoclonal antibody whose variable epitope mirrors a tumour antigen (CA-125) highly expressed in the epithelial ovarian

carbohydrate structure gal alpha 1-3Gal beta 1-4GlcNAc-R (the alpha-galactosyl epitope). The alpha-gal molecule is found in all mammals except catarrhines (apes

allergen test) and FITkit testing service [1] E2Tag epitope tagging technology MAbs to HIV/SIV proteins, epitope tags anti-IgG antibodies QMCF Technology - a

specific chemical constitution of each antibody. The antigenic determinant or epitope is recognized by the paratope of the antibody, situated at the variable

known to contain physicochemically conserved B cells and T cells specific epitopes, which can be exploited to design vaccine. Recombinant domains of the E

known: beta Ls(a) which carries the Ge3 epitope and gamma Ls(a) which carries both the Ge2 and Ge3 epitopes. This antigen is also known as the Rs(a)

dye-quenching debated recently. The Toponome Imaging Systems (TIS) and multi-epitope-ligand cartographs (MELC) represent different stages of the ICM technological

SMAD signaling cascade. The wrist epitope motif on BMP-2 has a high-affinity binding site for BMPR-IA. The knuckle epitope motif on BMP-2 has a low-affinity

configuration. Additionally, it allows the mapping of epitopes as antibodies of overlapping epitopes will be associated with an attenuated signal compared

Opsonization involves the binding of an opsonin (e.g., antibody) to an epitope on a pathogen. After opsonin binds to the membrane, phagocytes are attracted

been described. The best HEV marker currently available is a carbohydrate epitope recognized by the monoclonal antibody (mAb) MECA-79, which stains all HEVs

HIV IMMUNODOMINANT EPITOPE KM1(LPPVVAKEI) 1e28: NONSTANDARD PEPTIDE BINDING OF HLA-B*5101 COMPLEXED WITH HIV IMMUNODOMINANT EPITOPE KM2(TAFTIPSI) 1efx:

shape. This formation occurs due to an immunological reaction between an epitope on the central cell's surface and a receptor or antibody on a red cell

Epitope Detection in Monocytes (EDIM) is a technology that uses the innate immune system's mechanisms to detect biomarkers or antigens in immune cells

the DRB1*01:01 allele. DRB1*01:01 and most DR4 have in common a 'shared epitope'. In this hypothesis a common region of the beta chain, positions 67 to

mega pool (CD4+ pool) consisted of 221 predicted HLA class II CD4+ T-cell epitope peptides covering the entire viral proteome except for the spike protein

Mayte (5 December 2019). "Novel Bead-Based Epitope Assay is a sensitive and reliable tool for profiling epitope-specific antibody repertoire in food allergy"

because it was engineered using genes from the repeat ('R') and T-cell epitope ('T') of the pre-erythrocytic circumsporozoite protein (CSP) of the Plasmodium

serotypes. Ways JP, Lawlor DA, Wan AM, Parham P (1987). "A transposable epitope of HLA-B7, B40 molecules". Immunogenetics. 25 (5): 323–8. doi:10.1007/BF00404425

published twelve iterations of experimental intranasal, multivalent, multi-epitope peptide vaccine formulas, and according to the RaDVaC website, by early

the Vasostatin-1, namely ChgA29-42 has been identified as the antigenic epitope recognized by diabetogenic BDC2.5 T cells from type 1 diabetes prone NOD

serotypes. Ways JP, Lawlor DA, Wan AM, Parham P (1987). "A transposable epitope of HLA-B7, B40 molecules". Immunogenetics. 25 (5): 323–8. doi:10.1007/BF00404425

identification of cancer-associated gene variants and the classification of immune epitopes. Immunoinformatics is using the basic bioinformatics tools such as ClustalW

(EGFR) on the outer membrane of normal and tumor cells. The matuzumab epitope has been mapped to domain III of the extracellular domain of the EGFR.

specifically inhibits the CROP domain of TcdB. It recognizes a specific epitope on toxin TcdB and has high affinity for that region. The GTD domain does

and Mycoplasma pneumoniae. Antibodies to a GM1 epitope as well as to one with the GT1a or GD3 epitope were found in different strains of Campylobacter

a second monoclonal antibody (M5) which recognizes an epitope N-terminal from the M30® epitope. M30 Apoptosense® ELISA can be combined with the M65® ELISA

galactofuranose glycoconjugates. The exocyclic 1,2-diol of galactofuranose is the epitope recognized by the putative chordate immune lectin intelectin. Because UGM

have to determine whether the influenza virus could quickly mutate the epitope targeted by FI6 and escape recognition by FI6 after exposure. A more important

PMID 11689626. Chen X (May 2014). "Tapasin modification on the intracellular epitope HBcAg18-27 enhances HBV-specific CTL immune response and inhibits hepatitis

be a convergence of both epitope and paratope conformations in an antibody response against a flexible immunodominant epitope (J. Immunol, 2002, 168:2371)

motifs. The gamma epitopes identified are DQ2-"γ-I", -"γ-II" (γ30), -"γ-III", -"γ-IV", -"γ-VI" and -"γ-VII" Some of these epitopes are recognized in children

IgG, and IgA. The epitope XNAs target is an α-linked galactose moiety, galactose-alpha-1,3-galactose (also called the α-Gal epitope), produced by the

S T D V D E P L E V F I S A P R S E) (Bolded areas represent the core epitope.) Szostecki C, Guldner HH, Netter HJ, Will H (1990). "Isolation and characterization

Structure Analysis of NY-ESO-1 epitope, SLLMWITQC, in complex with HLA-A2 1s9x: Crystal Structure Analysis of NY-ESO-1 epitope analogue, SLLMWITQA, in complex

Dälken B, Engling A, Krömer W, Heim K, et al. (April 2015). "A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique

anti-alpha-Gal antibodies, which caused the loss of alpha1,3-galactose epitope on glycoproteins in humans, apes, and old world monkeys. The disappearance

anti-CD20 monoclonal antibody whose epitope is distinct from that of rituximab. Ofatumumab binds to a distinct epitope on small and large extracellular loops

other, monomeric MHC-epitope complexes cannot provide stable binding. This problem can be solved by using multimerized MHC-epitopes, which increases the

membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production". Sci Transl Med. 6 (243): 243ra85. doi:10.1126/scitranslmed

receptor. cDNA cloning, cell surface expression, and construction of a novel epitope-bearing analog". J. Biol. Chem. 267 (13): 9101–6. doi:10.1016/S0021-9258(19)50394-5

functional analysis of the human reduced folate carrier by hemagglutinin epitope insertion". The Journal of Biological Chemistry. 274 (23): 16269–78. doi:10

proteolytic fragments of gliadin, or synthetic peptides that represent epitopes of gliadin. After developing an immune response, B-cells from mice can

strands during PCR. The binding does not depend on a specific sequence or epitope on collagen, enabling CHPs to target denatured collagen chains of different

antibodies to the α-amino acid citrulline. The presence of HLA-DR shared epitope (SE) genes was a risk factor for RA with the presence of anticitrulline

(1994). "HLA-B67: a member of the HLA-B16 family that expresses the ME1 epitope". Tissue Antigens. 43 (1): 38–43. doi:10.1111/j.1399-0039.1994.tb02294

Banting GS, Pym B, Darling SM, Goodfellow PN (1989). "The MIC2 gene product: epitope mapping and structural prediction analysis define an integral membrane

(380-389)is a major immunogenic epitope of HSP90 followed by EP1 (1-12) and EP8 (488-498). Knowledge of binding epitopes on the autoantigen is necessary

fsTnT is linked with fsTnI genes (Fig. 1). Sequence homology and protein epitope allosteric similarity data suggest that TnT gene was originated by duplication

FHV is a platform for nanotechnology and nanomedicine, for example, for epitope display and vaccine development. Viral entry into host cells occurs via

(fsTnI)-fsTnT, ssTnI-cardiac (cTnT) and cTnI-ssTnT gene pairs. Sequence and epitope conservation studies suggested that genes encoding the muscle type specific

Cytoskeleton Disease Biomarkers EMBL Protein Binders (Affinomics) Enzymes Epitope Tags Extracellular Matrix Microbes (Bacteria, Fungi, Viruses) Neurodevelopment

Goncalvez AP, Men R, Wernly C, Donau O, Engle RE, Purcell RH (Dec 2007). "Epitope determinants of a chimpanzee dengue virus type 4 (DENV-4)-neutralizing

"RBP1L1, a retinoblastoma-binding protein-related gene encoding an antigenic epitope abundantly expressed in human carcinomas and normal testis". J Natl Cancer

Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms

on Sec22 for packaging into COPII-coated vesicles is a conformational epitope". Molecular Cell. 26 (3): 403–14. doi:10.1016/j.molcel.2007.03.017. PMID 17499046

region in IA-2 is probably the early antibody target.  Followed by multiple epitope spreading which is believed to take place in the early development of the

titin extends into the center of the sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins"

digestion pattern of Gt with four proteases defines monoclonal antibody epitope". J. Biol. Chem. 266 (21): 14072–81. doi:10.1016/S0021-9258(18)92811-5

earlier predictions of the protein structure and site of the major T-cell epitope. The Bet v 1 protein comprises 6 anti-parallel beta-strands and 3 alpha-helices

Scola B, Raoult D (January 2002). "Monoclonal antibodies to immunodominant epitope of Tropheryma whipplei". Clinical and Diagnostic Laboratory Immunology

and as an indication of the development of tumors in the body. The Apo10 epitope plays a special role in this process. This characteristic section of the

Marxer A, Sutherland DR, et al. (2003). "Antibody W7C5 defines a CD109 epitope expressed on CD34+ and CD34- hematopoietic and mesenchymal stem cell subsets"

for protein retention in the endoplasmic reticulum contain a conserved epitope". EMBO Journal. 11 (6): 2345–2355. doi:10.1002/j.1460-2075.1992.tb05294

immune system. Addition of fucose sugars by fucosyltransferases forms Lewis epitopes and the scaffold for blood group determinants. Addition of a fucose alone

reflects the sequence of developmental expression as determined by double epitope-tagging competition". J. Cell Sci. 109 (8): 2089–99. doi:10.1242/jcs.109

domains, such as long non-coding RNAs (lncRNAs), protein-binding motifs, or epitope tags for immunochemistry. This allows for investigation of the functionality

novel tubulin-dependent protein kinase forming a paired helical filament epitope on tau". J. Biochem. 104 (3). Tokyo: 319–21. doi:10.1093/oxfordjournals

Hori H, Kanamori T, Mizuta T, et al. (1995). "Human laminin M chain: epitope analysis of its monoclonal antibodies by immunoscreening of cDNA clones

transports digested viral antigen epitope peptides from the cytosol to the endoplasmic reticulum, allowing these epitopes to be combined with MHC class I

single antibody clone and have binding specificity for one particular epitope. In the case of solanezumab, the antibody is designed to bond to the amyloid-β

(May 1995). "Ultrastructural localization of ras-related proteins using epitope-tagged plasmids". The Journal of Histochemistry and Cytochemistry. 43 (5):

normal human lymphocytes in vitro is down-regulated by a conserved HIV p24 epitope". Immunol. Lett. 33 (3): 307–14. doi:10.1016/0165-2478(92)90078-3. PMID 1385321

normal human lymphocytes in vitro is down-regulated by a conserved HIV p24 epitope". Immunol. Lett. 33 (3): 307–14. doi:10.1016/0165-2478(92)90078-3. PMID 1385321

Mattey DL, Thomson W, Ollier WE, et al. (2007). "Association of DRB1 shared epitope genotypes with early mortality in rheumatoid arthritis: results of eighteen

reflects the sequence of developmental expression as determined by double epitope-tagging competition". J. Cell Sci. 109 (8): 2089–99. doi:10.1242/jcs.109

C (November 2000). "Antigenicity and immunogenicity of the HIV-1 gp41 epitope ELDKWA inserted into permissive sites of the MalE protein". Vaccine. 19

2001). "Isolation of a new melanoma antigen, MART-2, containing a mutated epitope recognized by autologous tumor-infiltrating T lymphocytes". J. Immunol

Honda, W.; Kanehisa, M. (2006). "MIMOX: A web tool for phage display based epitope mapping". BMC Bioinformatics. 7: 451. doi:10.1186/1471-2105-7-451. PMC 1618411

Perosa F, Vicenti C, Racanelli V, et al. (2010). "The immunodominant epitope of centromere-associated protein A displays homology with the transcription

Fujii H, Miura H, Miyasaka N, Nishioka K, Miyamoto T (May 1990). "Fine epitope mapping of the human SS-B/La protein. Identification of a distinct autoepitope

Furukawa KS, Furukawa K, Real FX, et al. (1989). "A unique antigenic epitope of human melanoma is carried on the common melanoma glycoprotein gp95/p97"

VDRL) Goodpasture's disease Anti-glomerular basement membrane antibody Epitope on noncollagen domain of type IV collagen Small vessel vasculitis Microscopic

PMID 10321733. Cao J, Gao T, Giuliano AE, Irie RF (Feb 1999). "Recognition of an epitope of a breast cancer antigen by human antibody". Breast Cancer Research and

inflammation distinguishes three types of arthritis through differential epitope exposure". Journal of Immunology. 185 (7): 4154–68. doi:10.4049/jimmunol

protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation"

genus Iris FLAG (chemotherapy), a chemotherapy regimen FLAG-tag, a unique epitope added to proteins in biochemistry Flagging (botany), a growth pattern that

1997). "Targeted antipeptide antibodies to cytochrome P450 2C18 based on epitope mapping of an inhibitory monoclonal antibody to P450 2C51". Archives of

Raymond F.; Criswell, Lindsey A. (2004). "Particular HLA–DRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitis". Arthritis

kininogen binding site of prekallikrein. Evidence for a discontinuous epitope formed by distinct segments of the prekallikrein heavy chain". J. Biol

"Identification of a novel HLA-A*0201-restricted, cytotoxic T lymphocyte epitope in a human glioma-associated antigen, interleukin 13 receptor alpha2 chain"

produced using the "anti-idiotypic" process closely resembles the original epitope of the antigen, these antibodies can be used to induce immune responses

Salter RD (January 2000). "Modification of the amino terminus of a class II epitope confers resistance to degradation by CD13 on dendritic cells and enhances

Cambareri B, Vadas MA, Lopez AF (1996). "A discontinuous eight-amino acid epitope in human interleukin-3 binds the alpha-chain of its receptor". J. Biol

receptor. cDNA cloning, cell surface expression, and construction of a novel epitope-bearing analog". J. Biol. Chem. 267 (13): 9101–6. doi:10.1016/S0021-9258(19)50394-5

trigger downstream immune responses. The strength of the bond between the epitope of the antigen and the paratope of the antibody will determine the affinity

a so-called “functional genus claim,” which defines an antibody by its epitope, the specific target against which it binds. Although, Amgen did discover

normal human lymphocytes in vitro is down-regulated by a conserved HIV p24 epitope". Immunology Letters. 33 (3): 307–14. doi:10.1016/0165-2478(92)90078-3

Sriskandarajah, M; Stallcup, WB; Baeuerle, PA; Kufer, P (August 2010). "Epitope distance to the target cell membrane and antigen size determine the potency

or rigidity could alter the specificity of the antibody to its intended epitope. While the framework region doesn't directly interact with antigen, its

steps occur leading to creation of peptide subunit vaccine; Epitope recognition Epitope optimization Peptide immunity improvement When compared with

novel P-selectin glycoprotein ligand-1 monoclonal antibody recognizes an epitope within the tyrosine sulfate motif of human PSGL-1 and blocks recognition

Sequences. PLoS ONE 8(6): e67008 Lbtope: Improved Method for Linear B-Cell Epitope Prediction Using Antigen's Primary Sequence. PLoS ONE 8(5): e62216 Open

(January 1994). "Membrane topology of aquaporin CHIP. Analysis of functional epitope-scanning mutants by vectorial proteolysis". The Journal of Biological Chemistry

"Identification and characterization of human eosinophil cationic protein by an epitope-specific antibody". J. Leukoc. Biol. 69 (6): 1027–35. doi:10.1189/jlb.69

Xu Z, Thakur A, Fox M, Tan SS, DiGiammarino E, et al. (April 2020). "Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for

intestinal transglutaminase, has a high density of overlapping T-cell epitopes. This increases the likelihood that the DQ2 isoform will bind, and stay

Naito I, Ando K, Yonezawa T, Sado Y, Hirakawa S, et al. (February 2002). "Epitope-defined monoclonal antibodies against multiplexin collagens demonstrate

(2004). "Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers" (PDF). Science. 303 (5662): 1352–5. Bibcode:2004Sci

evade this response. Flagellins contain a Toll-like receptor 5 (TLR5) epitope, a region recognized by the immune receptor TLR5. There are variations

epitopes on dendritic cells, and found a novel epitope of ICAM-1. Through the development of an anti-ICAM1 antibody against the newly found epitope,

PMID 11911017. S2CID 28608175. Tomono Y, Naito I, Ando K, et al. (2002). "Epitope-defined monoclonal antibodies against multiplexin collagens demonstrate

2006). "Membrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domains"

Grötzinger J (Jan 2004). "Direct determination of the interleukin-6 binding epitope of the interleukin-6 receptor by NMR spectroscopy". J. Biol. Chem. 279

specificities, including the significance of fucosylation and of the sialyl-Tn epitope. Sialic acid-binding immunoglobulin superfamily lectins". Journal of Biological

cell membranes. However, 7E11-C5.3 exclusively targets an intracellular epitope of PSMA, thus only binding to dead or dying cells. PSMA shares homology

protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation"

receptor potential 3 as inferred from glycosylation-scanning mutagenesis and epitope immunocytochemistry". J. Biol. Chem. 273 (15): 8675–9. doi:10.1074/jbc

protein contains a highly immunogenic minor histocompatibility antigen epitope of 9 amino acids, B6(dom1). Like ITM1 (MIM 601134), STT3B is homologous

cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein". The Biochemical Journal

role of dipeptidyl peptidase IV in the digestion of an immunodominant epitope in celiac disease". Dipeptidyl Aminopeptidases in Health and Disease. Advances

Piechaczyk M, Pau B, Malthièry Y (February 1992). "A major human thyroglobulin epitope defined with monoclonal antibodies is mainly recognized by human autoantibodies"

apoptosis by binding to the CD3 epitope at T cells surface on wild-type colitis model. Once binding to this epitope, gal-4 promotes apoptosis of T cells

Sato K, Miyokawa N, Kimura S, Kinouchi R, Katagiri M (1998). "Tyrosinase epitope recognized by an HLA-DR-restricted T-cell line from a Vogt-Koyanagi-Harada

hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe". J. Biol. Chem

environmental exposures to infections and drugs as well as the phenomenon of epitope spreading are also known to cause bullous pemphigoid. Diagnosis of bullous

1987). "Centrosomal proteins and lactate dehydrogenase possess a common epitope in human cell lines". Proceedings of the National Academy of Sciences of

14-3-3η (YWHAH) levels above 0.5 ng/ml Carriership of HLA-DR4 "Shared Epitope" alleles Family history of RA Poor functional status Socioeconomic factors

inflammation distinguishes three types of arthritis through differential epitope exposure". Journal of Immunology. 185 (7): 4154–68. doi:10.4049/jimmunol

slow skeletal muscle TnI (ssTnI)-cTnT, and cTnI-ssTnT pairs. Sequence and epitope conservation studies suggested that genes encoding the muscle type-specific

of milk lipocalin Bos d 5 through binding to its immunodominant T-cell epitope". Scientific Reports. 8 (1): 1598. Bibcode:2018NatSR...8.1598H. doi:10

proteogenic amino acids thereby closely resembling a natural peptide binding epitope. Introduced modifications usually aim to increase the stability of the

erythrocyte membrane band 3 studied with monoclonal antibody directed against an epitope on the cytoplasmic fragment of band 3". European Journal of Biochemistry

selection of human antibodies from phage display repertoires to a single epitope of an antigen TNF alpha. The ultimate clinical candidate, D2E7, was created

26996. PMC 4083010. PMID 24492943. Gao W, Xu Y, Liu J, Ho M (May 2016). "Epitope mapping by a Wnt-blocking antibody: evidence of the Wnt binding domain

"Self-Assembled Peptide Amphiphile Micelles Containing a Cytotoxic T-Cell Epitope Promote a Protective Immune Response In Vivo". Advanced Materials. 24 (28):

"BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II". EMBO J. 19 (13): 3314–24. doi:10.1093/emboj/19.13

"BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II". EMBO J. 19 (13): 3314–24. doi:10.1093/emboj/19.13

Miyamoto K, Kawata A, Hayashi H (2004). "An aggregate-prone conformational epitope in trinucleotide repeat diseases". NeuroReport. 14 (18): 2331–5. doi:10

generated rabbit monoclonal antibodies targeting rare and poorly immunogenic epitopes of mesothelin, including the C terminus recognized by the YP218 antibody

Castiglione, F.; Mueller, D.; Srivastava, A (2020). "A candidate multi-epitope vaccine against SARS-CoV-2". Scientific Reports. 10 (10895). Nature Research:

PMID 2174397. Johnsson N, Johnsson K, Weber K (August 1988). "A discontinuous epitope on p36, the major substrate of src tyrosine-protein-kinase, brings the

endoplasmic reticulum into the external plasma membrane of the cell. The epitope peptide is bound on extracellular parts of the class I MHC molecule. Thus

1". Gregersen PK, Silver J, Winchester RJ (November 1987). "The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility

neurotrophin-3 to p75LNGFR, TrkA, and TrkB mediated by a single functional epitope distinct from that recognized by trkC". J. Biol. Chem. 271 (10): 5623–7

therapy. B-cell immunotherapies link an immunogenic protein with a B-cell epitope and incorporate an adjuvant to produce a B-cell cancer vaccine that induces

expression on high endothelial venules, and decoration with the MECA-79 epitope". The American Journal of Pathology. 160 (5): 1669–81. doi:10.1016/S0002-9440(10)61114-5

4-hydroxynonenallysine) has been referred to as an "oxidation-specific epitope" and a lipid oxidation "degradation product". It is generated by the oxidative

and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies". J. Biol. Chem. 275 (22): 17122–9. doi:10.1074/jbc

A3~DQ6 superhaplotype. HLA-A3 selects HIV evolution for a mutation Gag KK9 epitope and results in a rapid decline in the CD8 T-cell response. CD8 T-cells

SB, Meadows SK, Roberts BS, et al. (October 2015). "CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins". Genome Research. 25 (10): 1581–9

cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein". The Biochemical Journal

also produce glycoproteins containing the galactose-alpha-1,3-galactose epitope, which can induce serious allergenic reactions, including anaphylactic

cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein". The Biochemical Journal

(EGF) receptor, partially overlapping but distinct from the EGF-binding epitope". The Journal of Biological Chemistry. 277 (38): 35671–81. doi:10.1074/jbc

"BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II". EMBO J. 19 (13): 3314–24. doi:10.1093/emboj/19.13

subsequently produce antibodies to other proteins through a process known as epitope spreading. The retroviral gag protein shows similarity to the La protein

(September 24, 2019). "Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD". Cell Reports. 28 (13): 3395–3405.e6. doi:10.1016/j

Le TT, et al. (February 2008). "Phase I trial of a CD8+ T-cell peptide epitope-based vaccine for infectious mononucleosis". Journal of Virology. 82 (3):

Zinc finger nuclease kits Empty backbones Species-specific expression Epitope tags Fusion proteins Selectable markers Fluorescent marker Viral vectors

CD20-like family crystal structure of rituximab fab in complex with an epitope peptide Identifiers Symbol CD20 Pfam PF04103 Pfam clan CL0347 InterPro

Kwong PD (2007). "Structural definition of a conserved neutralization epitope on HIV-1 gp120". Nature. 445 (7129): 732–737. Bibcode:2007Natur.445..732Z

Davies MJ, Renouf DV, Hounsell EF, Stern PL (Apr 2002). "Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen". The Biochemical Journal

calcium-binding monoclonal antibody that recognizes a non-calcium-binding epitope in the short consensus repeat units (SCRs) of complement C1r". Molecular

1001/archderm.93.3.296. PMID 5910871. Tanaka T, Furukawa F, Imamura S (May 1994). "Epitope mapping for epidermolysis bullosa acquisita autoantibody by molecularly

is a protease resistant 33mer that has 6 overlapping DQ2.5 restricted epitopes. This creates very strong binding of T-cells for DQ2.5-33mer complexes

are produced by the same B cell, they will be directed towards the same epitope, and are thus monoclonal antibodies. The next stage is a rapid primary

(May 2009). "To investigate protein evolution by detecting suppressed epitope structures". Journal of Molecular Evolution. 68 (5): 448–60. Bibcode:2009JMolE

Kimura K, Kawakami Y (October 2002). "Identification of an immunodominant epitope on RNA polymerase III recognized by systemic sclerosis sera: application

systems based on mammalian cells. Their monospecific binding to a specific epitope makes rAbs eligible not only for research purposes, but also as therapy

activated Th1 cell's T cell receptor (TCR) via pMHC-II in a process known as epitope spreading. Thus, the B cell presents the foreign peptide (modified gliadin)

DV, Roep BO (2007). "Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men". Ann. N. Y. Acad. Sci. 1103 (1): 192–5.

Neumann F, Wagner C, Preuss KD, et al. (2005). "Identification of an epitope derived from the cancer testis antigen HOM-TES-14/SCP1 and presented by

others as SolarCare Technologies Corp. In 2000, the company merged with Epitope, a company that had developed a way of testing for HIV. After the merger

number of HHT1 mutations, the crystal structure of endoglin shows that the epitope of anti-ENG monoclonal antibody TRC105 overlaps with the binding site for

localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag". Proceedings of the National Academy of Sciences of the United States

zona pellucida glycoproteins by growing mouse oocytes microinjected with epitope-tagged cDNAs for mZP2 and mZP3". Molecular Biology of the Cell. 13 (2):

linkage. In forming this bond transglutaminase becomes linked to T-cell epitopes on gliadin. B-cells with surface IgM that react to transglutaminase can

on Sec22 for packaging into COPII-coated vesicles is a conformational epitope". Mol. Cell. 26 (3): 403–14. doi:10.1016/j.molcel.2007.03.017. PMID 17499046

2004). "N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding"

W, Southwood S, Sette A, Lou Y (2005). "Characterization of the T-cell epitope that causes anti-GBM glomerulonephritis". Kidney Int. 68 (3): 1061–70.

Phillips RE, Cerundolo V.  1999. Generation of an Immunodominant CTL epitope is affected by proteasome subunit composition and stability of the antigenic

immunoassay may differ, e.g. an ELISA based on antibodies against the TK1 TK 210 epitope was shown to be twice as sensitive as a TK1 activity assay in distinguishing

protein 1 (PfEMP1) intracellular domain reveals a conserved interaction epitope". The Journal of Biological Chemistry. 287 (10): 7182–9. doi:10.1074/jbc

production of virus neutralizing antibodies. These antigenic sites, or epitopes, are categorized into regions I–IV and minor site a. Previous work has

as well as translational profiling through the affinity purification of epitope tagged ribosomes. These are useful and complementary methods, but neither

Galili, U (February 2008). "The Galalpha1,3Galbeta1,4GlcNAc-R (alpha-Gal) epitope: a carbohydrate of unique evolution and clinical relevance". Biochimica

inserted into a plant transformation vector to allow transcription or the epitope within the antigen is identified and the DNA fragment can be used to construct

(May 2009). "To investigate protein evolution by detecting suppressed epitope structures". Journal of Molecular Evolution. 68 (5): 448–60. Bibcode:2009JMolE

Resource Organism supplier, Data repository Indeed Job resource Immune Epitope Database and Analysis Resource Database, Data analysis service, Web service

monoclonal antibodies directed towards the 5-methylthio-d-xylofuranose (MTX) epitope and a silver amplification technology to enable higher diagnostic sensitivity

five amino acids in the fifteenth spectrin motif bears a highly antigenic epitope resembling an ankyrin-like p53 binding protein binding site. Fourthly,

Surface Antigen 1 (SAG1) Structure of the immunodominant epitope displayed by the Surface Antigen 1 (SAG1) of Toxoplasma gondii complexed to a monoclonal

(April 2009). "Antibody recognition of a highly conserved influenza virus epitope". Science. 324 (5924). New York, N.Y.: 246–51. Bibcode:2009Sci...324..246E

immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella

of selective binding or it may even involve modifying the target e.g. epitope retrieval in immunological assays or cutting down the target into pieces

on Sec22 for packaging into COPII-coated vesicles is a conformational epitope". Mol. Cell. 26 (3): 403–14. doi:10.1016/j.molcel.2007.03.017. PMID 17499046

Binder M, Otto F, Mertelsmann R, Veelken H, Trepel M (September 2006). "The epitope recognized by rituximab". Blood. 108 (6): 1975–1978. doi:10.1182/blood-2006-04-014639

and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies". The Journal of Biological Chemistry. 275 (22):

Pennisi D, Ehrmann I, Ellis P, Cooper L, et al. (December 1996). "An H-YDb epitope is encoded by a novel mouse Y chromosome gene". Nature Genetics. 14 (4):

developers of EpiVacCorona represent the protein regions containing B-cell epitopes that should be recognized by the human immune system. These peptides are

and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies". The Journal of Biological Chemistry. 275 (22):

Pochopien S, et al. (2004). "Identification of a sperm protein 17 CTL epitope restricted by HLA-A1". Int. J. Cancer. 107 (5): 863–5. doi:10.1002/ijc

immunodominant regions among promiscuous HLA-DR-restricted CD4+ T-cell epitopes on the tumor antigen MAGE-3". Blood. 101 (3): 1038–44. doi:10.1182/blood-2002-03-0933

peptide nucleic acid encoded oligosaccharides that mimic the carbohydrate epitope of HIV". Angew. Chem. Int. Ed. Engl. 48 (41): 7695–7700. doi:10.1002/anie

capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope". Proceedings of the National Academy of Sciences. 112 (4): 971–976. doi:10

major disadvantage in that antibodies targeted against conformational epitopes can not be detected. On top of that, false positive can occur and the disease

Conjugates with polytuftsin retain tuftsin-like effects and increase the epitope specific antibody production. Tuftsin sequence appears in all four classes

LAGE-1 expression in bladder cancer and evidence of a new NY-ESO-1 T-cell epitope in a patient with bladder cancer". Cancer Immunity Archive. 3 (1): 19.

N-terminal M-protein-based vaccine as well as the M-protein vaccine (minimal epitope J8 vaccine) are two vaccines for GAS that are currently getting close or

5′-3′ direction. Briefly, a protein of interest (engineering one with an epitope tag can be useful for immunoprecipitation) is crosslinked in vivo to its

M005670200. PMID 10922374. Ball LJ, Kühne R, Hoffmann B, et al. (2000). "Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity

PMID 17500065. Munoz IM, Jowsey PA, Toth R, Rouse J (2007). "Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular

(May 2009). "To investigate protein evolution by detecting suppressed epitope structures". Journal of Molecular Evolution. 68 (5): 448–60. Bibcode:2009JMolE

Yu-Ting, Hung (March 2017). "Immunization with a streptococcal multiple-epitope recombinant protein protects mice against invasive group A streptococcal

L, Neve RL (1988). "Partial sequence of MAP2 in the region of a shared epitope with Alzheimer neurofibrillary tangles". J. Neurochem. 51 (2): 587–98.

neuroblastoma and small-cell lung cancer via binding a conformational epitope". Cell Reports. Medicine. 2 (7): 100344. doi:10.1016/j.xcrm.2021.100344

PMID 2504281. Cunningham, B. C.; Wells, J. A. (2 June 1989). "High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis".

Plasmodium falciparum circumsporozoite gene: amino acid sequence of repetitive epitope". Science. 225 (4662): 628–630. doi:10.1126/science.6204384. ISSN 0036-8075

stronger bond with actin.20 More importantly the discovered that this epitope is exposed in normal α-catenin when there is thrombin activity hence the

52 kDa Ro/SSA binds native 60 kDa Ro/SSA: identification of a tertiary epitope with components from 60 kDa Ro/SSA and 52 kDa Ro/SSA". Scandinavian Journal

Mark J.; Bhandari, Rashna; Wittrup, K.Dane (2004). "Domain-level antibody epitope mapping through yeast surface display of epidermal growth factor receptor

"T cell responses and virus evolution: loss of HLA A11-restricted CTL epitopes in Epstein-Barr virus isolates from highly A11-positive populations by

Bander, N. H.; Lewis, J. S.; Grimm, J. (2011). "Targeting the internal epitope of prostate-specific membrane antigen with 89Zr-7E11 immuno-PET". The Journal

F. M.; Bahadur, G.; Wraith, D.; McMichael, A. J. (28 March 1986). "The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be

26996. PMC 4083010. PMID 24492943. Gao W, Xu Y, Liu J, Ho M (May 2016). "Epitope mapping by a Wnt-blocking antibody: evidence of the Wnt binding domain

lipooligosaccharide: phase-variable accessibility of the phosphorylcholine epitope". Journal of Clinical Microbiology. 38 (12): 4412–4419. doi:10.1128/JCM

antigen, α-GalCer is able to stimulate a strong immune response against the epitope. The CD1d:glycolipid:TCR interaction activates the iNKT cell which can

Lin J, Shen R, Fisher PE, Goldstein NI, Fisher PB (July 1996). "Surface-epitope masking and expression cloning identifies the human prostate carcinoma

"Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody". The Journal of Biological Chemistry

2016). "Understanding ForteBio's Sensors for High-Throughput Kinetic and Epitope Screening for Purified Antibodies and Yeast Culture Supernatant". Journal

downstream kinetochore targets (such as tension-sensing 3F3/2 phospho-epitope) of Plk1, which is important for recruitment of spindle assembly checkpoint

ribosomal subunit fused to an epitope tag such as green fluorescent protein. After cell lysis, antibodies targeting the epitope are used to isolate mRNAs

has also pioneered a modification of mass spectrometry and dual-affinity epitope tagging that enables efficient and accurate classification of multi-protein

S, Fleckenstein B, Aeschlimann D, Sollid LM (Nov 2010). "Gluten T cell epitope targeting by TG3 and TG6; implications for dermatitis herpetiformis and

with rheumatoid arthritis negative for rheumatoid factor and the shared epitope". Arthritis and Rheumatism. 50 (6): 1770–3. doi:10.1002/art.20280. PMID 15188352

Fikes J, Wentworth P, et al. (1995). "Identification of potential CTL epitopes of tumor-associated antigen MAGE-1 for five common HLA-A alleles". Mol

hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe". J. Biol. Chem

Liotta LA (June 1996). "AAMP, a newly identified protein, shares a common epitope with alpha-actinin and a fast skeletal muscle fiber protein". Experimental

for protein retention in the endoplasmic reticulum contain a conserved epitope". EMBO Journal. 11 (6): 2345–2355. doi:10.1002/j.1460-2075.1992.tb05294

frame shift) to the GCA, polyalanine-encoding frame and introduce a novel epitope to the C terminus of Htt exon 1 (APAAAPAATRPGCG). Several diseases have

a common human infection that can be detected by conformational capsid epitope immunoassays". International Journal of Cancer. 125 (6): 1250–6. doi:10

52 kDa Ro/SSA binds native 60 kDa Ro/SSA: identification of a tertiary epitope with components from 60 kDa Ro/SSA and 52 kDa Ro/SSA". Scand. J. Immunol

the production of nitric oxide (NO), a molecule involved in learning. Epitope recognition contributes to cerebellar involvement. Reduced GABA levels

Totowa, NJ. Elizabeth F Hounsell and David V Renouf (1998) Oligosaccharide epitope diversity and therapeutic potential. Advances in Experimental Medicine

phorbol ester-induced oligomerization of CD44 variant isoforms containing epitope v9 and subsequently suppresses expression of urokinase-type plasminogen

PMID 1688010. Pacholczyk, Tadeusz; Sweadner, Kathleen J. (1997-04-15). "Epitope and mimotope for an antibody to the Na, K-ATPase". Protein Science. 6 (7):

zona pellucida glycoproteins by growing mouse oocytes microinjected with epitope-tagged cDNAs for mZP2 and mZP3". Mol. Biol. Cell. 13 (2): 530–541. doi:10

a common human infection that can be detected by conformational capsid epitope immunoassays". International Journal of Cancer. 125 (6): 1250–6. doi:10

affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric

Computational HLA Binding as an Early Filter to the Mass Spectrometry-Based Epitope Discovery Workflow". Cancers. 13 (10): 2307. doi:10.3390/cancers13102307

one single drug. The composition can be made of mAb targeting different epitopes of a same protein (homo-combination) or mAb targeting different proteins

James P. Allison first discovered a clonally expressed T-cell surface epitope in murine T lymphoma. In 1983, Ellis Reinherz first defined the structure

probe the array. The query protein was tagged with hemagglutinin (HA) epitope. Thus, the interaction between the two proteins was visualized with the

analyte captured is detected via a biotinylated antibody against a secondary epitope of the protein, followed by a streptavidin-R-phycoerythrin treatment. The

contains a large amino-terminal extracellular domain homologous to an epitope of Sjögren's Syndrome". Biochemical and Biophysical Research Communications

neurotrophin-3 to p75LNGFR, TrkA, and TrkB mediated by a single functional epitope distinct from that recognized by trkC". The Journal of Biological Chemistry

"Quantifying viable virus-specific T cells without a priori knowledge of fine epitope specificity". Nature Medicine. 12 (10): 1208–1212. doi:10.1038/nm1413.

PMC 33495. PMID 11344270. Zeng GF, Pypaert M, Slayman CL (January 2004). "Epitope tagging of the yeast K(+) carrier Trk2p demonstrates folding that is consistent

cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein". Biochem. J. 320 (Pt

Szostak showed that fusions between a synthetic mRNA and its encoded myc epitope could be enriched from a pool of random sequence mRNA-polypeptide fusions

Grötzinger J (January 2004). "Direct determination of the interleukin-6 binding epitope of the interleukin-6 receptor by NMR spectroscopy". The Journal of Biological

SW, Malek NP, Plentz RR, Schmid E (2020). "Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular

peptides selected from phage display experiment to map conformational epitopes. Some of the fast and efficient computational methods are available online

Milford E, Weiner H, Hafler DA. T cell recognition of an immunodominant MBP epitope in MS. Nature 346, 183. 2001 Baecher-Allan C, Brown JA, Freeman GJ, Hafler

applied in genetic association analysis so that the effects and roles of the epitopes shared by several HLA alleles can be identified. Sequence features and

Bates IR, Feix JB, Boggs JM, Harauz G (February 2004). "An immunodominant epitope of myelin basic protein is an amphipathic alpha-helix". The Journal of

the disease. Evidence implicating cytomegalovirus (CMV) as the original epitope of the immune reaction is limited, as is parvovirus B19. Organic solvents

"Characteristics of a monoclonal antibody (WT-31) that recognizes a common epitope on the human T cell receptor for antigen". Journal of Immunology. 135 (3):

2017). "High-Resolution Structure Analysis of Antibody V5 Conformational Epitope on Human Papillomavirus 16". Viruses. 9 (12): 374. doi:10.3390/v9120374

antigenomic open reading frame of the hepatitis delta virus encodes the epitope(s) of both hepatitis delta antigen polypeptides p24 delta and p27 delta"

(2004). "Autoantigenicity of DFS70 is restricted to the conformational epitope of C-terminal alpha-helical domain". J. Autoimmun. 23 (3): 221–31. doi:10

MHC peptide region involved in the presentation of a pathogenic T-cell epitope". Crit Rev Immunol. 21 (1–3): 1–27. doi:10.1615/CritRevImmunol.v21.i1-3

Kalos M (April 2004). "Identification of naturally processed CD8 T cell epitopes from prostein, a prostate tissue-specific vaccine candidate". European

hyperresponsiveness.” Immune Escape in RSV Genetic variations in viral epitopes and adjacent regions affect protein folding, post-transcriptional modifications

of rabbit monoclonal antibodies (e.g. YP218, YP223) that recognize rare epitopes of mesothelin, including poorly immunogenic sites close to the C terminal

broken down into pieces in both of these antigens. Less commonly, the NC16a epitope on BP180 has been linked to LABD. IgA antibodies directed against various

Scott, J.; Smith, G. (1990-07-27). "Searching for peptide ligands with an epitope library". Science. 249 (4967). American Association for the Advancement

influenza and because T-cells respond to conserved epitopes. The challenge for developers is that these epitopes are on internal protein domains that are only

are "potential targets of autoantibodies" and (2) "one of the autoimmune epitopes in XRCC4 coincides with a sequence that is a nexus for radiation-induced

titin extends into the center of the sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins"

JT (2019). "Improved identification of DNA double strand breaks: γ-H2AX-epitope visualization by confocal microscopy and 3D reconstructed images". Radiat

cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein". The Biochemical Journal

a maker mainly due to the assumption that DDX4 does not have a surface epitope and is only an intracellular protein. However recent evidence has shown

generates IL-10–dependent immunological tolerance associated with linked epitope suppression". Journal of Experimental Medicine. 206 (7): 1535–1547. doi:10

Nakayama E (2005). "Identification of an HLA-A24-restricted OY-TES-1 epitope recognized by cytotoxic T-cells". Microbiol. Immunol. 49 (11): 1009–16

"Multiple sclerosis patients have a high frequency of an HLA-DQ beta epitope defined by a human-human hybridoma antibody". Tissue Antigens. 33 (5):

0544. PMID 8921398. Stricker R, Kalbacher H, Reiser G (Aug 1997). "The epitope recognized by a monoclonal antibody in the myelin-associated protein CNP"

tools (Primer design, Gel mobility and Maps, Plasmapper, siRNA design Epitope prediction), Save research logs, Create custom toolbars Accession number

titin extends into the center of the sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins"

Kong Xiangpeng and Susan Zolla-Pazner for "Peptides Mimicking HIV-1 Viral Epitopes in the V2 Loop for the Gp120 Surface Envelope Glycoprotein" (American Inventors)"

B, Yeste A, Nyirenda M, Kenison J, Rahbari R, et al. (December 2014). "Epitope spreading as an early pathogenic event in pediatric multiple sclerosis"

designing a structure-guided evolution approach to identify antigenic epitopes on AAVs that are capable of evading neutralizing antibodies from the immune

(EGF) receptor, partially overlapping but distinct from the EGF-binding epitope". The Journal of Biological Chemistry. 277 (38): 35671–81. doi:10.1074/jbc

4.0 license. Rahman, M. (2000). "Identification, characterization and epitope mapping of proteins encoded by putative allergenic napin genes from Brassica

transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer". Nature Communications. 14 (1): 1986. Bibcode:2023NatCo

Yoshitomo K, Watanabe S, Suzuki F, Yamaguchi N (Oct 1992). "Use of an epitope-tagged cDNA library to isolate cDNAs encoding proteins with nuclear localization

an increased proliferative response to the immunodominant CD4(+) T-cell epitope in human interferon-beta". Genes Immun. 5 (1): 1–7. doi:10.1038/sj.gene

hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe". J. Biol. Chem

developed methods to make active RITs in which the major B cell and T cell epitopes have been identified and silenced. An RIT with reduced immunogenicity that

development. COX15 associates with Shy1 in distinct complexes, C-terminal epitope tagging of COX15 selectively affects its association to cytochrome c oxidase

vaccinia virus class-I epitopes presentation by HSV-ICP47 enhances the immunogenicity of a TAP-independent cancer vaccine epitope". International Journal

also led to personalized cancer targeting immunotherapies, where antibody epitopes for cancer antigens are predicted using proteogenomics to create medicines

by the MPM2 monoclonal antibody and determination of the phosphorylated epitope". Proc Natl Acad Sci U S A. 91 (2): 714–8. Bibcode:1994PNAS...91..714W

wide range of proteins. For instance, the central region in a consensus epitope of myelin basic protein consists of the sequence: proline, arginine, threonine

Surolia A (1999). "Thermodynamic analyses reveal role of water release in epitope recognition by a monoclonal antibody against the human guanylyl cyclase

Retrieved 2022-10-14. Davis FM, Gossett LA, Chang TW (January 1991). "An epitope on membrane-bound but not secreted IgE: implications in isotype-specific

1640–1645. PMID 7523797. Deans JP, Polyak MJ (February 2008). "FMC7 is an epitope of CD20". Blood. 111 (4): 2492, author reply 2493-2492, author reply 2494

López-Sánchez I, Vega FM, et al. (2007). "Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular

K, et al. (2009). "DNA vaccine encoding chimeric protein encompassing epitopes of human ZP3 and ZP4: immunogenicity and characterization of antibodies"

size of the micropeptide can also lead to difficulties in designing an epitope from which to target the antibody. Genome editing can be used to add FLAG/MYC

(March 1998). "Promiscuous T-cell recognition of a rubella capsid protein epitope restricted by DRB1*0403 and DRB1*0901 molecules sharing an HLA DR supertype"

2019.[dead link] Luque, D; González, JM; Gómez-Blanco, J; et al. (2012). "Epitope Insertion at the N-Terminal Molecular Switch of the Rabbit Hemorrhagic

cargo interactions via protein-protein interactions and phosphothreonine epitope recognition. KIF1A has many mechanisms in place to regulate activation

retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein". Proceedings of the National Academy of

Ternette, Nicola; Eisenlohr, Laurence C. (November 2023). "Cryptic MHC-E epitope from influenza elicits a potent cytolytic T cell response". Nature Immunology

JH, Old LJ (August 1994). "Fibroblast activation protein: purification, epitope mapping and induction by growth factors". International Journal of Cancer

Plasmodium falciparum Circumsporozoite Gene: Amino Acid Sequence of Repetitive Epitope. V Enea, J Ellis, F Zavala, DE Arnot, A Asavanich, A Masuda, I Quakyi,

Karlsruhe GmbH "ICSD". 161,030 IEDB Immune Epitope Database National Institute of Allergy and Infectious Diseases Epitopes mainly peptides and carbohydrates "IEDB"

focus on identifying an immunotherapeutic Cytotoxic T lymphocyte (CTL) epitope in hepatocellular carcinoma (HCC)-associated antigen HCA587 and its potential

Typhimurium biofilm disruption by a human antibody that binds a pan-amyloid epitope on curli". Nature Communications. 11 (1): 1007. Bibcode:2020NatCo..11.1007T

Holt AK, Rosenberg SA. Antitumor immunization with a minimal peptide epitope (G9-209-2M) leads to a functionally heterogeneous CTL response. J Immunother

KappaMab (MDX-1097) is specific for KMA and binds to a unique conformational epitope in the kappa constant region that is presented when kappa free light chain

Webby, R., Doherty, P.C. and Turner, S.J., 2006. Addition of a prominent epitope affects influenza A virus-specific CD8+ T cell immunodominance hierarchies

"Human immunodeficiency virus type 1 gp120 mimics a hidden monomorphic epitope borne by class I major histocompatibility complex heavy chains". The Journal

in the brain, because this TCR also recognized a different but related epitope that is expressed at low levels in the brain. That CARs are potentially

der Zeijst, B A; Hensen, E J (September 1991). "Localization of a T-cell epitope within the nucleocapsid protein of avian coronavirus". Immunology. 74 (1):

Gateway “attR” recombination sequences and elements such as promoters and epitope tags, but not ORFs) using the proprietary enzyme mix, “LR Clonase”. Thousands

receptors, and observed plant species Category DAMP Molecular structure or epitope Source or precursor Receptor or signaling regulator Species Epidermis cuticle

vaccines had started clinical trials. BiondVax identified 9 conserved epitopes of the influenza virus and combined them into a recombinant protein called

Cichorium somatic embryogenesis: effect of beta-glucosyl Yariv reagent and epitope localisation during embryo development". Planta. 211 (3): 305–314. doi:10

immunoproteasome, is the processing of numerous MHC class-I restricted T cell epitopes. This gene encodes a member of the proteasome B-type family, also known

PMID 22563565. Gao, Wei; Xu, Yongmei; Liu, Jian; Ho, Mitchell (May 17, 2016). "Epitope mapping by a Wnt-blocking antibody: evidence of the Wnt binding domain

against CTAG1B was from a metastatic melanoma patient. 3 HLA-A2 restricted epitopes in CTAG1B were identified as the recognition sites for CD8+ cytotoxic T

(a capture antibody and a reporter antibody, each binding to a unique epitope), confers greater specificity and lower background signal compared with

Dransfield, I; Hogg, N (1 December 1989). "Regulated expression of Mg2+ binding epitope on leukocyte integrin alpha subunits". The EMBO Journal. 8 (12): 3759–3765

melanogaster Potential basis of the neural anti-horseadish peroxidase epitope". J. Biol. Chem. 276 (30): 28058–67. doi:10.1074/jbc.M100573200. PMID 11382750

Cα−1-Cα0 and Cα+1-Cα0 vectors. HSE is used in predicting discontinuous B-cell epitopes. Song et al. have developed an online webserver termed HSEpred to predict

(Nov 2010). "Toward next generation plasma profiling via heat-induced epitope retrieval and array-based assays". Molecular & Cellular Proteomics. 9 (11):

diseases, without relying on hyper-phosphorylated epitopes. These antibodies were raised against an epitope within the RRM2 domain (amino acid residues 198–216)

study it has been suggested that an immunogenic peptide pool containing epitopes that can be effective against all the high-risk HPV strains circulating

(2004). "Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers". Science. 303 (5662): 1352–5. Bibcode:2004Sci...303

limitations due to the cross linking step in ChIP-Seq protocols that can promote epitope masking and generate false-positive binding sites. As well, ChIP-seq suffers

analysis of the sta56 gene and precise identification of a strain-specific epitope". Infection and Immunity. 58 (7): 2076–2084. doi:10.1128/IAI.58.7.2076-2084

was halted at least 3 times. Cel-Sci has also worked on LEAPS (Ligand Epitope Antigen Presentation System), a system of therapeutic vaccines for rheumatoid

(2010-03-18). "Identification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO)". Journal of Biomedicine & Biotechnology

limitations due to the cross linking step in ChIP-Seq protocols that can promote epitope masking and generate false-positive binding sites. As well, ChIP-seq suffers

PK; Swerdlow, H; Satija, R; Smibert, P (September 2017). "Simultaneous epitope and transcriptome measurement in single cells". Nature Methods. 14 (9):

protein purification from plant material using the eight-amino acid StrepII epitope". Plant Mol Biol. 55 (1): 135–147. doi:10.1007/s11103-004-0501-y.

newly-synthesised versus mature viral proteins as antigen sources for CD4 and CD8 epitope display". PLOS Pathogens. 5 (12): e1000699. doi:10.1371/JOURNAL.PPAT.1000699

limitations due to the cross linking step in ChIP-Seq protocols that can promote epitope masking and generate false-positive binding sites. As well, ChIP-seq suffers

transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer". Nature Communications. 14 (1): 1986. Bibcode:2023NatCo

polysaccharide chain (O-antigen) of the lipopolysaccharide. Certain LPS epitopes have been examined to determine their function in antigenic specificity

024. PMC 3031711. PMID 21112773. Gao W, Xu Y, Liu J, Ho M (May 2016). "Epitope mapping by a Wnt-blocking antibody: evidence of the Wnt binding domain

Chattopadhyay PK, Swerdlow H, et al. (September 2017). "Simultaneous epitope and transcriptome measurement in single cells". Nature Methods. 14 (9):

CITE-Seq (Cellular Indexing of Transcriptomes and Epitopes by Sequencing) is a method for performing RNA sequencing along with gaining quantitative and

subsets of T cells, B Cells, and Monocytes. Represents a carbohydrate epitope that contains a sulfoglucuronyl residue. CD58 a membrane protein present

Drena; Honavar, Vasant G. (2017). "In Silico Prediction of Linear B-Cell Epitopes on Proteins". Prediction of Protein Secondary Structure. Methods in Molecular

skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile." The Journal of Cell Biology 115, no. 1 (1991): 97–107. Kruger

FSL peptides. Furthermore, FSL constructs may have a restricted antigen/epitope and may not react with a monoclonal antibody unless the FSL construct and