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Longer titles found: Insulin receptor substrate (view), Insulin receptor substrate 1 (view)

searching for Insulin receptor 251 found (462 total)

IRS2 (1,479 words) [view diff] exact match in snippet view article find links to article

Insulin receptor substrate 2 is a protein that in humans is encoded by the IRS2 gene. This gene encodes the insulin receptor substrate 2, a cytoplasmic

Downregulation and upregulation (2,178 words) [view diff] exact match in snippet view article find links to article

elevated hormone concentration. This process is illustrated by the insulin receptor sites on target cells, e.g. liver cells, in a person with type 2 diabetes

IRS4 (921 words) [view diff] exact match in snippet view article find links to article

Insulin receptor substrate 4 is a protein that in humans is encoded by the IRS4 gene. IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein

BAIAP2 (1,415 words) [view diff] exact match in snippet view article find links to article

involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central

PIK3R1 (3,136 words) [view diff] no match in snippet view article find links to article

AK, Wong AJ (1996). "A Grb2-associated docking protein in EGF- and insulin-receptor signalling". Nature. 379 (6565): 560–4. Bibcode:1996Natur.379..560H

GRB14 (1,043 words) [view diff] exact match in snippet view article find links to article

effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate

Cixutumumab (617 words) [view diff] exact match in snippet view article find links to article

cellular proliferation. IGF-1R, a receptor tyrosine kinase of the insulin receptor superfamily overexpressed by many cancer cell types, stimulates cell

GRB2-associated-binding protein 1 (1,611 words) [view diff] no match in snippet view article find links to article

Wong AJ (April 1996). "A Grb2-associated docking protein in EGF- and insulin-receptor signalling". Nature. 379 (6565): 560–4. Bibcode:1996Natur.379..560H

MiR-144 (471 words) [view diff] exact match in snippet view article find links to article

involved in erythropoiesis. One of the identified targets of miR-144 is insulin receptor substrate 1. miR-144 has been identified as one of a number of potential

Daf-2 (1,034 words) [view diff] exact match in snippet view article find links to article

single celled organisms to mammals. DAF-2 is the only member of the insulin receptor family in C. elegans but it corresponds, in form and function, to multiple

AP3S1 (462 words) [view diff] exact match in snippet view article find links to article

Morin M, Czech MP, Heller-Harrison RA (November 1998). "Interaction of insulin receptor substrate-1 with the sigma3A subunit of the adaptor protein complex-3

Aganirsen (888 words) [view diff] exact match in snippet view article find links to article

GS-101) is a 25 mer DNA antisense oligonucleotide therapeutic inhibiting insulin receptor substrate-1 (IRS-1), which is being investigated as a topical treatment

SH2B2 (994 words) [view diff] exact match in snippet view article find links to article

Gustafson TA (1999). "Identification of the APS protein as a novel insulin receptor substrate". J. Biol. Chem. 274 (16): 11186–93. doi:10.1074/jbc.274

SORBS1 (1,890 words) [view diff] exact match in snippet view article find links to article

Saltiel AR (Feb 1998). "A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes". Molecular and Cellular Biology. 18

PTPRF (1,451 words) [view diff] exact match in snippet view article find links to article

(1992). "Insulin receptor protein-tyrosine phosphatases. Leukocyte common antigen-related phosphatase rapidly deactivates the insulin receptor kinase by

LMBRD1 (472 words) [view diff] exact match in snippet view article find links to article

cobalamin metabolic process insulin receptor internalization negative regulation of glucose import negative regulation of insulin receptor signaling pathway negative

VASH1 (503 words) [view diff] exact match in snippet view article find links to article

healthy longevity with reduced expression of insulin receptor, insulin receptor substrate 1, and insulin receptor substrate 2 in their white adipose tissue"

SNF1LK2 (676 words) [view diff] exact match in snippet view article find links to article

2003). "Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2"

Wayne Hendrickson (407 words) [view diff] exact match in snippet view article find links to article

research group pioneered solving the crystal structures of CD4, CD8, insulin receptor kinase, Hsp70, SRC kinase, HIV gp120, cadherin, FGF and many other

IMD domain (682 words) [view diff] exact match in snippet view article find links to article

domain of approximately 250 amino acids found at the N-terminus in the insulin receptor tyrosine kinase substrate p53 (IRSp53/BAIAP2) and in the evolutionarily

PTPN2 (1,206 words) [view diff] exact match in snippet view article find links to article

Klingler-Hoffmann M, Fodero-Tavoletti MT, et al. (2003). "Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP". Mol. Cell. Biol

Protein kinase C zeta type (2,598 words) [view diff] exact match in snippet view article find links to article

activity metal ion binding protein serine/threonine kinase activity insulin receptor substrate binding transferase activity 14-3-3 protein binding potassium

Dephosphorylation (2,170 words) [view diff] exact match in snippet view article find links to article

dephosphorylation of insulin receptor substrate-1/2, Akt, and ERK1/2, phosphoproteins are shown to be involved in insulin receptor signaling, and in vitro

PIK3R2 (1,401 words) [view diff] exact match in snippet view article find links to article

1995). "Distinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domains". The Journal of

SOCS7 (642 words) [view diff] exact match in snippet view article find links to article

Nicholson SE, Baca M, Hilton DJ, Alexander WS (Jul 2002). "SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation"

MAPK8 (1,828 words) [view diff] exact match in snippet view article find links to article

2002). "Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action". J. Biol

YWHAE (1,633 words) [view diff] exact match in snippet view article find links to article

(epsilon) interacts with the insulin-like growth factor I receptor and insulin receptor substrate I in a phosphoserine-dependent manner". J. Biol. Chem. 272

Janet Mary Lord (675 words) [view diff] exact match in snippet view article find links to article

where she studied the impact of hypoglycaemic drugs and obesity on insulin receptor binding. She joined the University of Oxford as a research fellow.

SHC1 (1,641 words) [view diff] exact match in snippet view article find links to article

functional significance of Shc in insulin signaling as a substrate of the insulin receptor". Endocrine Journal. 47 (4): 373–81. doi:10.1507/endocrj.47.373. PMID 11075717

Mir-278 microRNA precursor family (301 words) [view diff] exact match in snippet view article find links to article

(2009). "Dicer-1-dependent Dacapo suppression acts downstream of Insulin receptor in regulating cell division of Drosophila germline stem cells". Development

Kenneth Chiacchia (850 words) [view diff] exact match in snippet view article find links to article

of the rat adipocyte insulin receptor is dependent upon the presence of insulin: the class I disulfide of the insulin receptor is extracellular. [In

Suppressor of cytokine signaling 1 (1,957 words) [view diff] exact match in snippet view article find links to article

(SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation". The Journal of Experimental Medicine

Douglas Emlen (370 words) [view diff] exact match in snippet view article find links to article

contributes to species differences in the shape of horns, and how the insulin receptor (InR) pathway modulates the size of male weapons in response to the

SOCS6 (677 words) [view diff] exact match in snippet view article find links to article

"Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance". J

GSK3A (212 words) [view diff] exact match in snippet view article find links to article

response negative regulation of glucose import negative regulation of insulin receptor signaling pathway regulation of autophagy of mitochondrion negative

BAIAP2L1 (449 words) [view diff] exact match in snippet view article find links to article

cytoskeleton nucleoplasm actin cytoskeleton cytoplasm Biological process insulin receptor signaling pathway regulation of actin filament polymerization plasma

TSC2 (1,843 words) [view diff] exact match in snippet view article find links to article

regulation of GTPase activity neural tube closure negative regulation of insulin receptor signaling pathway positive chemotaxis viral process regulation of small

Escargot (transcription factor) (1,987 words) [view diff] exact match in snippet view article

proboscis. Esg controls somatic stem cell maintenance through repressing insulin receptor pathway. Gain-of-function mutations in esg in neurons suppresses seizures

GPR21 (199 words) [view diff] exact match in snippet view article find links to article

plasma membrane membrane Biological process negative regulation of insulin receptor signaling pathway glucose homeostasis signal transduction positive

Nicotinamide phosphoribosyltransferase (3,216 words) [view diff] exact match in snippet view article find links to article

lower plasma glucose levels in mice by binding to and activating the insulin receptor. However, the physiological relevance of visfatin is still in question

Gonadotropic cell (336 words) [view diff] case mismatch in snippet view article find links to article

Infertility in Female Mice due to a Pituitary-Specific Knockout of the Insulin Receptor (IR)". Cell Metabolism. 12 (3): 295–305. doi:10.1016/j.cmet.2010.06

NUCKS1 (662 words) [view diff] exact match in snippet view article find links to article

nucleus chromatin nucleolus Biological process positive regulation of insulin receptor signaling pathway transcription by RNA polymerase II glucose homeostasis

TFG (gene) (1,073 words) [view diff] exact match in snippet view article

functional significance of Shc in insulin signaling as a substrate of the insulin receptor". Endocrine Journal. 47 (4): 373–81. doi:10.1507/endocrj.47.373. PMID 11075717

FUT7 (1,001 words) [view diff] exact match in snippet view article find links to article

3-fucosyltransferase-VII regulates the signaling molecules of the insulin receptor pathway". The FEBS Journal. 274 (2): 526–38. doi:10.1111/j.1742-4658

NISCH (977 words) [view diff] exact match in snippet view article find links to article

integrin. In humans, this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from

Signal transducing adaptor protein (666 words) [view diff] exact match in snippet view article find links to article

adaptor protein 2 GRB2 – Growth factor receptor-bound protein 2 IRS1 – Insulin receptor substrate 1 LDLRAP1 – low-density lipoprotein receptor adaptor protein

ATP6V0D2 (160 words) [view diff] exact match in snippet view article find links to article

membrane proton-transporting V-type ATPase complex Biological process insulin receptor signaling pathway transferrin transport ion transport ion transmembrane

Klaus H. Hofmann (2,331 words) [view diff] exact match in snippet view article find links to article

biotinyl-insulin receptor complex could then be displaced by biotin. With this tool, Hofmann and his coworkers successfully isolated a fully active insulin receptor

Unfolded protein response (3,579 words) [view diff] exact match in snippet view article find links to article

tyrosine residues of insulin receptor substrate (IRS-1), which is the substrate for insulin tyrosine kinase (the insulin receptor). C-Jun N-terminal kinase

GRB2 (9,365 words) [view diff] no match in snippet view article find links to article

"SH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinase". The Biochemical

SERPIN A12 (1,122 words) [view diff] exact match in snippet view article find links to article

phosphorylation of tyrosine and, then, the activation of the insulin receptor substrate. The insulin receptor substrate, in turn, activates protein kinase-B by stimulating

Chimerin (803 words) [view diff] exact match in snippet view article find links to article

β2-Chimerin can be linked to a fusion gene that is associated with a key insulin receptor that causes people to have decreased levels of insulin. Chimerin+Proteins

ATP6V1E2 (466 words) [view diff] exact match in snippet view article find links to article

proton-transporting two-sector ATPase complex, catalytic domain Biological process insulin receptor signaling pathway ion transmembrane transport ion transport transferrin

Sodium tungstate (625 words) [view diff] case mismatch in snippet view article find links to article

Antidiabetic Agent Sodium Tungstate Activates Glycogen Synthesis through an Insulin Receptor-independent Pathway. The Journal of Biological Chemistry, Vol. 278

ATP6V1G3 (633 words) [view diff] exact match in snippet view article find links to article

V-type ATPase complex Biological process proton transmembrane transport insulin receptor signaling pathway ion transmembrane transport ion transport transferrin

ATP6V1C2 (250 words) [view diff] exact match in snippet view article find links to article

domain Biological process positive regulation of Wnt signaling pathway insulin receptor signaling pathway ion transmembrane transport ion transport transferrin

P110α (1,929 words) [view diff] exact match in snippet view article find links to article

activity protein serine/threonine kinase activity protein binding insulin receptor substrate binding ATP binding 1-phosphatidylinositol-3-kinase activity

NCOA5 (560 words) [view diff] exact match in snippet view article find links to article

cytoskeleton extracellular space Biological process negative regulation of insulin receptor signaling pathway regulation of transcription, DNA-templated glucose

PTPRE (1,046 words) [view diff] exact match in snippet view article find links to article

membrane membrane nucleus Biological process negative regulation of insulin receptor signaling pathway protein dephosphorylation peptidyl-tyrosine dephosphorylation

Atrophin 1 (1,921 words) [view diff] exact match in snippet view article find links to article

a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate". Human Molecular Genetics. 8 (6): 947–57

MAD2L1 (1,975 words) [view diff] exact match in snippet view article find links to article

with the carboxyl terminus of the insulin receptor but not with the IGFIR. Evidence for release from the insulin receptor after activation". J. Biol. Chem

PTPRB (792 words) [view diff] exact match in snippet view article find links to article

1992). "Sequential dephosphorylation of a multiply phosphorylated insulin receptor peptide by protein tyrosine phosphatases". Biochemistry. 31 (17): 4232–4238

Caveolae (1,462 words) [view diff] exact match in snippet view article find links to article

transcytosis of albumin in endothelial cells or for internalization of the insulin receptor in primary adipocytes. Caveolae have been shown to be required for

ATP2A3 (1,109 words) [view diff] exact match in snippet view article find links to article

Histochemistry. 77 (4): 229–30. PMID 12503734. Borge PD, Wolf BA (2003). "Insulin receptor substrate 1 regulation of sarco-endoplasmic reticulum calcium ATPase

Parvulin 14 (1,505 words) [view diff] exact match in snippet view article find links to article

also found within the cytoplasm. Cytoplasm: Par14 interacts with the insulin receptor substrate (IRS-1) and enhances insulin-induced tyrosine-phosphorylation

Espin (protein) (759 words) [view diff] exact match in snippet view article

cell dendritic spines and bind the Src homology 3 adapter protein insulin receptor substrate p53". J. Neurosci. 23 (4): 1310–9. doi:10.1523/JNEUROSCI

GNAI2 (1,518 words) [view diff] exact match in snippet view article find links to article

regulation of calcium ion-dependent exocytosis positive regulation of insulin receptor signaling pathway positive regulation of ERK1 and ERK2 cascade negative

SHANK1 (1,948 words) [view diff] exact match in snippet view article find links to article

PMID 12626503. Soltau M, Richter D, Kreienkamp HJ (Dec 2002). "The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42"

GSK-3 (5,581 words) [view diff] exact match in snippet view article find links to article

other aspects of glucose homeostasis, including the phosphorylation of insulin receptor IRS1 and of the gluconeogenic enzymes phosphoenolpyruvate carboxykinase

ATP6V0A4 (735 words) [view diff] exact match in snippet view article find links to article

complex endosome membrane extracellular exosome Biological process insulin receptor signaling pathway excretion transferrin transport ossification vacuolar

2001 in science (1,196 words) [view diff] case mismatch in snippet view article find links to article

(April 6, 2001). "Extension of Life-Span by Loss of CHICO, a Drosophila Insulin Receptor Substrate Protein". Science. 292 (5514): 104–106. Bibcode:2001Sci.

Piceatannol (758 words) [view diff] case mismatch in snippet view article find links to article

Inhibits Adipogenesis via Modulation of Mitotic Clonal Expansion and Insulin Receptor-dependent Insulin Signaling in Early Phase of Differentiation". Journal

Sprouty protein (454 words) [view diff] exact match in snippet view article find links to article

EGFR-mediated signaling in the eye. Most notably, in humans, it suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK

List of causes of hypoglycemia (1,265 words) [view diff] exact match in snippet view article find links to article

tumors Immunopathologic hypoglycemia Insulin Insulin-like growth factor Insulin receptor antibodies Insulinoma Intrauterine growth retardation Jamaican vomiting

ZBTB7B (570 words) [view diff] exact match in snippet view article find links to article

CD8-positive, alpha-beta T cell differentiation positive regulation of insulin receptor signaling pathway positive regulation of brown fat cell differentiation

PTPRA (1,328 words) [view diff] exact match in snippet view article find links to article

dephosphorylation MAPK cascade peptidyl-tyrosine dephosphorylation insulin receptor signaling pathway regulation of molecular function modulation of chemical

ATP6V0A2 (838 words) [view diff] exact match in snippet view article find links to article

intracellular organelle perinuclear region of cytoplasm Biological process insulin receptor signaling pathway transferrin transport vacuolar proton-transporting

ATP6V0C (806 words) [view diff] exact match in snippet view article find links to article

granule membrane integral component of membrane Biological process insulin receptor signaling pathway lysosomal lumen acidification transferrin transport

Protein O-GlcNAc transferase (2,734 words) [view diff] exact match in snippet view article find links to article

Thiruneelakantapillai L, Lane MD, Hart GW (February 2010). "Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked

ATP2A1 (1,315 words) [view diff] exact match in snippet view article find links to article

PMID 8889548. Algenstaedt P, Antonetti DA, Yaffe MB, Kahn CR (1997). "Insulin receptor substrate proteins create a link between the tyrosine phosphorylation

ATP6V1H (889 words) [view diff] exact match in snippet view article find links to article

vacuolar proton-transporting V-type ATPase, V1 domain Biological process insulin receptor signaling pathway endocytosis transferrin transport mitigation of host

Pleckstrin homology domain (1,434 words) [view diff] exact match in snippet view article find links to article

Non-receptor tyrosine kinases belonging to the Btk/Itk/Tec subfamily. Insulin receptor substrate 1 (IRS-1). Regulators of small G-proteins: 64 RhoGEFs of

ATP6V1E1 (723 words) [view diff] exact match in snippet view article find links to article

complex, catalytic domain extracellular exosome Biological process insulin receptor signaling pathway transferrin transport ion transport ion transmembrane

Bradykinin receptor B2 (1,311 words) [view diff] exact match in snippet view article find links to article

"Bradykinin enhances GLUT4 translocation through the increase of insulin receptor tyrosine kinase in primary adipocytes: evidence that bradykinin stimulates

INSL3 (1,213 words) [view diff] exact match in snippet view article find links to article

ontology Molecular function protease binding signaling receptor binding insulin receptor binding hormone activity G protein-coupled receptor binding Cellular

Shaodong Guo (1,073 words) [view diff] exact match in snippet view article find links to article

establishing the critical role of insulin and suppressed-Foxo1 via the insulin receptor substrate (IRS) proteins in control of cardiac structure and function

SNX4 (568 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function insulin receptor binding leptin receptor binding epidermal growth factor receptor binding protein binding phosphatidylinositol

ATP6V1D (680 words) [view diff] exact match in snippet view article find links to article

exosome plasma membrane specific granule membrane Biological process insulin receptor signaling pathway transferrin transport ion transport ion transmembrane

TUBD1 (306 words) [view diff] exact match in snippet view article find links to article

SE, Baca M, Hilton DJ, Alexander WS (July 2002). "SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation"

PRKCB1 (675 words) [view diff] exact match in snippet view article find links to article

activation protein phosphorylation B cell activation negative regulation of insulin receptor signaling pathway mitotic nuclear membrane disassembly negative regulation

ATP6AP1 (703 words) [view diff] exact match in snippet view article find links to article

membrane proton-transporting V-type ATPase complex Biological process insulin receptor signaling pathway transferrin transport pH reduction ion transport

Age-1 (1,462 words) [view diff] case mismatch in snippet view article find links to article

Muñoz, Manuel J.; Riddle, Donald L.; Ruvkun, Gary (December 2002). "Insulin Receptor Substrate and p55 Orthologous Adaptor Proteins Function in the Caenorhabditis

ATP6V1G1 (714 words) [view diff] exact match in snippet view article find links to article

proton-transporting V-type ATPase complex extracellular exosome Biological process insulin receptor signaling pathway transferrin transport proton transmembrane transport

RPTOR (3,504 words) [view diff] exact match in snippet view article find links to article

phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation". Mol. Cell. Biol. 26 (1): 63–76. doi:10

Tolimidone (472 words) [view diff] exact match in snippet view article find links to article

Saporito MS (July 2012). "The Lyn kinase activator MLR-1023 is a novel insulin receptor potentiator that elicits a rapid-onset and durable improvement in glucose

ATP6V1A (703 words) [view diff] exact match in snippet view article find links to article

extracellular exosome cytoplasm vacuolar membrane Biological process insulin receptor signaling pathway transferrin transport ion transport ion transmembrane

David Gems (1,471 words) [view diff] exact match in snippet view article find links to article

Linda (2001) "Extension of life span by loss of CHICO, a Drosophila insulin receptor substrate protein"". Science. "Selman, Colin, Lingard, Steven, Gems

ATP6V1B2 (757 words) [view diff] exact match in snippet view article find links to article

exosome endomembrane system apical plasma membrane Biological process insulin receptor signaling pathway transferrin transport ion transport ion transmembrane

ZFP106 (401 words) [view diff] exact match in snippet view article find links to article

binding Cellular component nucleus nucleolus cytosol membrane nuclear speck Biological process insulin receptor signaling pathway Sources:Amigo / QuickGO

ASB6 (458 words) [view diff] exact match in snippet view article find links to article

interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex". J. Biol. Chem. 279 (37): 38881–8. doi:10.1074/jbc

SOGA1 (427 words) [view diff] exact match in snippet view article find links to article

extracellular space Biological process negative regulation of gluconeogenesis insulin receptor signaling pathway regulation of autophagy Sources:Amigo / QuickGO

ATP6V0D1 (667 words) [view diff] exact match in snippet view article find links to article

membrane proton-transporting V-type ATPase complex Biological process insulin receptor signaling pathway transferrin transport ion transport ion transmembrane

ATP6V0B (660 words) [view diff] exact match in snippet view article find links to article

macroautophagy vacuolar acidification ion transmembrane transport insulin receptor signaling pathway ion transport transferrin transport proton transmembrane

Adapter molecule crk (2,941 words) [view diff] exact match in snippet view article find links to article

"The insulin-like growth factor I receptor-induced interaction of insulin receptor substrate-4 and Crk-II". Endocrinology. 142 (5): 1835–40. doi:10.1210/endo

Maximum life span (5,393 words) [view diff] case mismatch in snippet view article find links to article

with ≈10% extension at 16 °C and 65% extension at 27 °C. Fat-specific Insulin Receptor KnockOut (FIRKO) mice have reduced fat mass, normal calorie intake

Diglyceride (925 words) [view diff] exact match in snippet view article find links to article

PMID 20376053. Petersen MC, Madiraju AK, Gassaway BM, et al. (2016). "Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance"

IGFBP1 (1,045 words) [view diff] exact match in snippet view article find links to article

process PERK-mediated unfolded protein response tissue regeneration insulin receptor signaling pathway regulation of cell growth negative regulation of

Cyclin D3 (1,604 words) [view diff] exact match in snippet view article find links to article

polymerase II regulation of cell population proliferation regulation of insulin receptor signaling pathway regulation of cyclin-dependent protein serine/threonine

Jose F. Caro (2,305 words) [view diff] exact match in snippet view article find links to article

in Type 2 Diabetes stands out the discovery of alterations in the insulin receptor kinase in the human liver. Also, in collaboration with Walter Pories

Hormone-sensitive lipase (1,904 words) [view diff] exact match in snippet view article find links to article

phosphorylated and when the dephosphorylation of Ser552 causes insulin to the insulin receptor, causing inhibition of lipolysis and stimulation of glucose transport

SNX2 (1,067 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function protein homodimerization activity insulin receptor binding leptin receptor binding epidermal growth factor receptor binding

AP20187 (147 words) [view diff] exact match in snippet view article find links to article

F; Auricchio, A (2007). "AP20187-mediated activation of a chimeric insulin receptor results in insulin-like actions in skeletal muscle and liver of diabetic

FOXC2 (1,624 words) [view diff] exact match in snippet view article find links to article

embryonic skeletal system morphogenesis skeletal system development insulin receptor signaling pathway ureteric bud development regulation of transcription

SLA2 (430 words) [view diff] exact match in snippet view article find links to article

regulation of phosphatidylinositol 3-kinase activity negative regulation of insulin receptor signaling pathway phosphatidylinositol phosphate biosynthetic process

Dynamin-like 120 kDa protein (1,957 words) [view diff] exact match in snippet view article find links to article

L-glutamate negative regulation of apoptotic process positive regulation of insulin receptor signaling pathway membrane fusion response to curcumin Sources:Amigo

Photoperiodism (2,664 words) [view diff] exact match in snippet view article find links to article

"Photoperiod controls wing polyphenism in a water strider independently of insulin receptor signalling". Proceedings. Biological Sciences. 289 (1973): 20212764

ATP6V1C1 (814 words) [view diff] exact match in snippet view article find links to article

vacuolar proton-transporting V-type ATPase, V1 domain Biological process insulin receptor signaling pathway transferrin transport ion transport ion transmembrane

EIF4EBP2 (666 words) [view diff] exact match in snippet view article find links to article

intracellular anatomical structure Biological process social behavior insulin receptor signaling pathway modulation of chemical synaptic transmission negative

SPINA-GBeta (640 words) [view diff] exact match in snippet view article find links to article

the corresponding HOMA-Beta index. Together with the reconstructed insulin receptor gain (SPINA-GR), SPINA-GBeta provides the foundation for the definition

ATP6V0E1 (763 words) [view diff] exact match in snippet view article find links to article

phagocytic vesicle membrane membrane endosome membrane Biological process insulin receptor signaling pathway transferrin transport ion transport vacuolar acidification

Cinnamtannin B1 (405 words) [view diff] exact match in snippet view article find links to article

proanthocyanidin from Cinnamomum zeylanicum stimulates phosphorylation of insulin receptor in 3T3-L1 adipocyties" (PDF). Archived from the original (PDF) on 2008-05-28

Caveolin 2 (1,290 words) [view diff] exact match in snippet view article find links to article

vesicle nucleus protein-containing complex sarcolemma Biological process insulin receptor signaling pathway positive regulation of endothelial cell proliferation

Protein kinase, AMP-activated, alpha 1 (1,183 words) [view diff] exact match in snippet view article find links to article

oxidative stress intracellular signal transduction negative regulation of insulin receptor signaling pathway motor behavior regulation of stress granule assembly

MZB1 (559 words) [view diff] exact match in snippet view article find links to article

population proliferation apoptotic process regulation of B cell proliferation regulation of insulin receptor signaling pathway Sources:Amigo / QuickGO

ATP6V1B1 (883 words) [view diff] exact match in snippet view article find links to article

extrinsic component of synaptic vesicle membrane Biological process insulin receptor signaling pathway excretion calcium ion homeostasis transferrin transport

ATP6V1F (791 words) [view diff] exact match in snippet view article find links to article

V-type ATPase complex membrane extracellular exosome Biological process insulin receptor signaling pathway ion transport transferrin transport phagosome acidification

WDR6 (529 words) [view diff] exact match in snippet view article find links to article

2000.3012. PMID 10903905. Sano H, Liu SC, Lane WS, et al. (2002). "Insulin receptor substrate 4 associates with the protein IRAS". J. Biol. Chem. 277 (22):

GAPVD1 (794 words) [view diff] exact match in snippet view article find links to article

Stahl PD (September 2006). "Insulin-stimulated Interaction between insulin receptor substrate 1 and p85alpha and activation of protein kinase B/Akt require

FAM132A (237 words) [view diff] exact match in snippet view article find links to article

involved in cellular response to glucose stimulus positive regulation of insulin receptor signaling pathway positive regulation of protein kinase B signaling

SESN3 (422 words) [view diff] exact match in snippet view article find links to article

regulation of protein kinase B signaling TORC2 signaling regulation of insulin receptor signaling pathway cellular response to amino acid starvation cellular

ATPase, H+ transporting, lysosomal V0 subunit a1 (711 words) [view diff] exact match in snippet view article find links to article

intracellular organelle perinuclear region of cytoplasm Biological process insulin receptor signaling pathway transferrin transport vacuolar proton-transporting

OSBPL8 (565 words) [view diff] exact match in snippet view article find links to article

regulation of sequestering of triglyceride positive regulation of insulin receptor signaling pathway fat cell differentiation phosphatidylserine acyl-chain

CISH (protein) (1,525 words) [view diff] exact match in snippet view article

complex Biological process regulation of growth negative regulation of insulin receptor signaling pathway protein kinase C-activating G protein-coupled receptor

PIK3R3 (896 words) [view diff] exact match in snippet view article find links to article

3-kinase activity phosphatidylinositol-3-phosphate biosynthetic process insulin receptor signaling pathway positive regulation of protein phosphorylation cell

Interleukin 9 (2,308 words) [view diff] exact match in snippet view article find links to article

(September 1995). "Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases". The Journal of Biological Chemistry

ANKRD15 (533 words) [view diff] exact match in snippet view article find links to article

positive regulation of Wnt signaling pathway negative regulation of insulin receptor signaling pathway negative regulation of cell migration negative regulation

PPP4C (1,099 words) [view diff] exact match in snippet view article find links to article

(Nov 2004). "Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation". The

SOCS2 (1,147 words) [view diff] exact match in snippet view article find links to article

pathway negative regulation of apoptotic process negative regulation of insulin receptor signaling pathway cellular response to hormone stimulus growth hormone

PDK4 (2,535 words) [view diff] exact match in snippet view article find links to article

Cellular component mitochondrial matrix mitochondrion Biological process insulin receptor signaling pathway glucose homeostasis regulation of fatty acid oxidation

MTSS1 (745 words) [view diff] exact match in snippet view article find links to article

(2004). "A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein". J

PDK2 (1,929 words) [view diff] exact match in snippet view article find links to article

acetyl-CoA biosynthetic process from pyruvate cellular response to nutrient insulin receptor signaling pathway regulation of cellular ketone metabolic process regulation

SKIP (766 words) [view diff] exact match in snippet view article find links to article

transcription, DNA-templated response to insulin negative regulation of insulin receptor signaling pathway negative regulation of protein targeting to membrane

SNX1 (1,095 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function protein homodimerization activity insulin receptor binding leptin receptor binding epidermal growth factor receptor binding

GPLD1 (984 words) [view diff] exact match in snippet view article find links to article

extracellular matrix Biological process cellular response to calcium ion insulin receptor signaling pathway positive regulation of triglyceride biosynthetic

SNX1 (1,095 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function protein homodimerization activity insulin receptor binding leptin receptor binding epidermal growth factor receptor binding

GPLD1 (984 words) [view diff] exact match in snippet view article find links to article

extracellular matrix Biological process cellular response to calcium ion insulin receptor signaling pathway positive regulation of triglyceride biosynthetic

FOXO3 (2,230 words) [view diff] exact match in snippet view article find links to article

mitochondrial transcription negative regulation of cell migration insulin receptor signaling pathway positive regulation of autophagy positive regulation

Null allele (1,506 words) [view diff] exact match in snippet view article find links to article

"Early neonatal death in mice homozygous for a null allele of the insulin receptor gene". Nature Genetics. 12 (1): 106–9. doi:10.1038/ng0196-106. PMID 8528241

MTORC2 (3,678 words) [view diff] exact match in snippet view article find links to article

mTORC2 has tyrosine kinase activity and phosphorylates IGF-IR and insulin receptor at the tyrosine residues Y1131/1136 and Y1146/1151, respectively, leading

LIM domain (1,963 words) [view diff] exact match in snippet view article find links to article

protein contains three LIM domains at the c-terminal. It will bind insulin receptor internalization motif (InsRF) at LIM domain 3. LIM domain 2 binds Ret

Cyclin-dependent kinase 4 (2,367 words) [view diff] exact match in snippet view article find links to article

stimulus regulation of multicellular organism growth regulation of insulin receptor signaling pathway regulation of lipid biosynthetic process regulation

Caveolin 3 (2,508 words) [view diff] exact match in snippet view article find links to article

Lisanti MP, Myers MG, Ishikawa Y (1998). "Caveolin is an activator of insulin receptor signaling". J. Biol. Chem. 273 (41): 26962–8. doi:10.1074/jbc.273.41

Leptin (13,116 words) [view diff] exact match in snippet view article find links to article

individuals is due to a post leptin-receptor deficit, similar to the post-insulin receptor defect seen in type 2 diabetes. When leptin binds with the leptin receptor

VWA2 (523 words) [view diff] exact match in snippet view article find links to article

calcium-independent cell-matrix adhesion protein homooligomerization regulation of insulin receptor signaling pathway growth plate cartilage chondrocyte morphogenesis

CLK2 (948 words) [view diff] exact match in snippet view article find links to article

PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptor". Molecular Endocrinology. 15 (10): 1768–80. doi:10.1210/mend.15.10

RasGEF domain (540 words) [view diff] exact match in snippet view article find links to article

Margolis, B; Schlessinger, J (1993). "The function of GRB2 in linking the insulin receptor to Ras signaling pathways". Science. 260 (5116): 1953–5. Bibcode:1993Sci

PIK3CB (982 words) [view diff] exact match in snippet view article find links to article

1-phosphatidylinositol-4-phosphate 3-kinase activity protein binding insulin receptor substrate binding ATP binding phosphatidylinositol-4,5-bisphosphate

RAS p21 protein activator 1 (1,605 words) [view diff] exact match in snippet view article find links to article

(October 2001). "Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling". Mol. Cell. Endocrinol. 183 (1–2): 113–21. doi:10

PRKCQ (2,407 words) [view diff] exact match in snippet view article find links to article

negative regulation of T cell apoptotic process negative regulation of insulin receptor signaling pathway positive regulation of T cell activation membrane

TSC1 (2,424 words) [view diff] exact match in snippet view article find links to article

regulation of focal adhesion assembly myelination negative regulation of insulin receptor signaling pathway synapse organization regulation of translation hippocampus

Paraptosis (2,767 words) [view diff] exact match in snippet view article find links to article

O'Connor, R; Ravid, R; O'Neill, C (Feb 2010). "Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to

Adipogenesis (2,438 words) [view diff] exact match in snippet view article find links to article

of mature adipocytes. These genes include adipocyte protein (aP2), insulin receptor, glycerophosphate dehydrogenase, fatty acid synthase, acetyl CoA carboxylase

P70-S6 Kinase 1 (2,127 words) [view diff] exact match in snippet view article find links to article

response to insulin response to lipopolysaccharide negative regulation of insulin receptor signaling pathway cellular response to hormone stimulus long-term memory

BBSome (6,786 words) [view diff] exact match in snippet view article find links to article

signaling. The BBSome also traffics the insulin receptor, so insufficient BBSome function reduces the insulin receptor expression which translates into reduced

Sterol regulatory element-binding protein 1 (2,154 words) [view diff] exact match in snippet view article find links to article

complex Biological process positive regulation of histone deacetylation insulin receptor signaling pathway positive regulation of triglyceride biosynthetic

Hirsutism (2,913 words) [view diff] exact match in snippet view article find links to article

associated with androgen excess in women with autoantibodies to the insulin receptor". Ann. Intern. Med. 97 (6): 851–5. doi:10.7326/0003-4819-97-6-851.

FOXO4 (2,764 words) [view diff] exact match in snippet view article find links to article

muscle cell differentiation negative regulation of G0 to G1 transition insulin receptor signaling pathway negative regulation of angiogenesis multicellular

MSRA (gene) (1,219 words) [view diff] exact match in snippet view article

"Methionine sulfoxide reductase a affects insulin resistance by protecting insulin receptor function". Free Radic. Biol. Med. 56: 123–32. doi:10.1016/j.freeradbiomed

RIN1 (1,032 words) [view diff] exact match in snippet view article find links to article

Galvis A, Hall J, Kruk I, Veisaga M, et al. (2006). "Rin1 regulates insulin receptor signal transduction pathways". Exp. Cell Res. 312 (7): 1106–18. doi:10

IGFBP7 (2,499 words) [view diff] exact match in snippet view article find links to article

Yamanaka Y, Wilson EM, Rosenfeld RG, Oh Y (1998). "Inhibition of insulin receptor activation by insulin-like growth factor binding proteins". J. Biol

Adiponectin receptor 1 (1,405 words) [view diff] exact match in snippet view article find links to article

oxidation hormone-mediated signaling pathway positive regulation of insulin receptor signaling pathway positive regulation of receptor signaling pathway

CEBPB (2,328 words) [view diff] exact match in snippet view article find links to article

nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription". Molecular and Cellular Biology. 23 (8): 2720–2732

Phosphotyrosine interaction domain containing 1 (551 words) [view diff] exact match in snippet view article find links to article

regulation of mitochondrial membrane potential negative regulation of insulin receptor signaling pathway negative regulation of glucose import positive regulation

SOCS3 (1,922 words) [view diff] exact match in snippet view article find links to article

development negative regulation of apoptotic process negative regulation of insulin receptor signaling pathway regulation of interferon-gamma-mediated signaling

EB-eye (809 words) [view diff] exact match in snippet view article find links to article

data sets and the number of matches found in each of them. Search for insulin receptor Search for p53 Search for web production team Search for escherichia

ATP6V1G2 (1,782 words) [view diff] exact match in snippet view article find links to article

regulation of macroautophagy ion transport ion transmembrane transport insulin receptor signaling pathway proton transmembrane transport phagosome acidification

SMARCC1 (1,352 words) [view diff] exact match in snippet view article find links to article

protein-containing complex Biological process chromatin remodeling insulin receptor signaling pathway regulation of transcription, DNA-templated regulation

SOCS3 (1,922 words) [view diff] exact match in snippet view article find links to article

development negative regulation of apoptotic process negative regulation of insulin receptor signaling pathway regulation of interferon-gamma-mediated signaling

Transcytosis (2,229 words) [view diff] exact match in snippet view article find links to article

across the BBB via transport on brain endothelial receptors such as the insulin receptor or transferrin receptor. The transporter protein acts as a molecular

RHOQ (1,273 words) [view diff] exact match in snippet view article find links to article

projection Biological process positive regulation of glucose import insulin receptor signaling pathway regulation of actin cytoskeleton organization regulation

SHANK3 (1,551 words) [view diff] exact match in snippet view article find links to article

PMID 11431708. Soltau M, Richter D, Kreienkamp HJ (December 2002). "The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42"

Valerie Wojna (580 words) [view diff] exact match in snippet view article find links to article

Mayo, R., Nath, A., & Wojna, V. (2012). Soluble and cell-associated insulin receptor dysfunction correlates with severity of HAND in HIV-infected women

TCIRG1 (2,198 words) [view diff] exact match in snippet view article find links to article

vesicle Biological process protein catabolic process in the vacuole insulin receptor signaling pathway transferrin transport vacuolar proton-transporting

Philip Cohen (British biochemist) (1,422 words) [view diff] case mismatch in snippet view article

; Anawalt, Bradley; Blackman, Marc R.; Boyce, Alison (eds.), "The Insulin Receptor and Its Signal Transduction Network", Endotext, South Dartmouth (MA):

CUGBP1 (2,289 words) [view diff] exact match in snippet view article find links to article

"MBNL1 is the primary determinant of focus formation and aberrant insulin receptor splicing in DM1". J. Biol. Chem. 280 (7): 5773–80. doi:10.1074/jbc

Tubulin beta-4B chain (915 words) [view diff] case mismatch in snippet view article find links to article

S2CID 25518226. Krebs DL, Uren RT, Metcalf D, et al. (2002). "SOCS-6 Binds to Insulin Receptor Substrate 4, and Mice Lacking the SOCS-6 Gene Exhibit Mild Growth Retardation"

Cost of reproduction hypothesis (1,136 words) [view diff] exact match in snippet view article find links to article

example, in Drosophila melanogaster, females with a mutation in the insulin receptor gene (DInR) released less ecdysteroids and produced less juvenile hormone;

Angiotensin (3,127 words) [view diff] exact match in snippet view article find links to article

nucleus associative learning operant conditioning positive regulation of insulin receptor signaling pathway regulation of extracellular matrix assembly positive

APPL1 (1,166 words) [view diff] exact match in snippet view article find links to article

ligand cell cycle cell population proliferation signal transduction insulin receptor signaling pathway regulation of protein localization to plasma membrane

Sirtuin 1 (3,126 words) [view diff] exact match in snippet view article find links to article

kinase activity white fat cell differentiation positive regulation of insulin receptor signaling pathway negative regulation of transcription, DNA-templated

MAP3K1 (3,167 words) [view diff] exact match in snippet view article find links to article

"MEK kinase 1 interacts with focal adhesion kinase and regulates insulin receptor substrate-1 expression". The Journal of Biological Chemistry. 278 (6):

Klotho (biology) (3,786 words) [view diff] exact match in snippet view article

metabolic process phosphatidylinositol phosphate biosynthetic process insulin receptor signaling pathway fibroblast growth factor receptor signaling pathway

Phosphatidylethanolamine N-methyltransferase (3,536 words) [view diff] exact match in snippet view article find links to article

AMP-activated protein kinase (AMPK), and serine-307-phosphorylated insulin receptor substrate 1 (IRS1-s307), which blocks insulin-mediated signal transduction;

Branched-chain amino acid (3,422 words) [view diff] exact match in snippet view article find links to article

mTOR pathway, and S6 kinase is activated leading to inhibition of insulin receptor substrate through serine phosphorylation. In the cell the increased

Chromium in glucose metabolism (1,597 words) [view diff] no match in snippet view article find links to article

within the blood rise, insulin binds to the external subunit of the insulin-receptor proteins, and induces a conformational change. This change results

Forkhead box protein O1 (3,343 words) [view diff] exact match in snippet view article find links to article

cytoplasm cytosol nucleoplasm mitochondrion nucleus Biological process insulin receptor signaling pathway negative regulation of fat cell differentiation regulation

Transcription factor Sp1 (3,446 words) [view diff] exact match in snippet view article find links to article

nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription". Molecular and Cellular Biology. 23 (8): 2720–32

Interleukin 1 beta (3,305 words) [view diff] exact match in snippet view article find links to article

regulation of calcidiol 1-monooxygenase activity negative regulation of insulin receptor signaling pathway cellular response to mechanical stimulus positive

Jürgen Neffe (849 words) [view diff] exact match in snippet view article find links to article

Biochim. Biophys. Acta 856, 310-319 (1986) Demonstration that the insulin receptor undergoes an early structural modification following insulin binding;

CDC42 (3,698 words) [view diff] exact match in snippet view article find links to article

S2CID 10817327. Soltau M, Richter D, Kreienkamp HJ (December 2002). "The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42"

SHANK2 (1,590 words) [view diff] exact match in snippet view article find links to article

PMID 11583995. Soltau M, Richter D, Kreienkamp HJ (December 2002). "The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42"

Α-Catenin (2,888 words) [view diff] exact match in snippet view article find links to article

epidermal cells with ablated αE-catenin had increased responsiveness to insulin receptor signaling and elevation of Ras and MAPK signaling as well. 21, 22 In

PIK3C2A (1,142 words) [view diff] exact match in snippet view article find links to article

cytoplasmic vesicle clathrin-coated vesicle nucleus Biological process insulin receptor signaling pathway endocytosis epidermal growth factor receptor signaling

AKT1 (2,850 words) [view diff] exact match in snippet view article find links to article

receptor signaling pathway interleukin-18-mediated signaling pathway insulin receptor signaling pathway positive regulation of smooth muscle cell proliferation

North Sichuan Medical University (1,350 words) [view diff] exact match in snippet view article find links to article

(2009). "Systemic lupus erythematosus presenting as hypoglycaemia with insulin receptor antibodies and insulin autoantibodies". Lupus. 18 (5): 457–9. doi:10

Adenomatous polyposis coli (3,225 words) [view diff] exact match in snippet view article find links to article

Wnt signaling pathway Wnt signaling pathway protein deubiquitination insulin receptor signaling pathway positive regulation of cell death protein homooligomerization

Hypoglycemia (6,110 words) [view diff] exact match in snippet view article find links to article

hypoglycemia is due to antibodies formed against insulin receptors, called insulin receptor antibodies. The antibodies attach to insulin receptors and prevent

MBNL1 (1,142 words) [view diff] exact match in snippet view article find links to article

"MBNL1 is the primary determinant of focus formation and aberrant insulin receptor splicing in DM1". The Journal of Biological Chemistry. 280 (7): 5773–80

Disposition index (1,163 words) [view diff] exact match in snippet view article find links to article

beta cells ( G β {\displaystyle G_{\beta }} or SPINA-GBeta) times the insulin receptor gain ( G R {\displaystyle G_{R}} or SPINA-GR): D I f = G β ⋅ G R {\displaystyle

Infertility in polycystic ovary syndrome (1,734 words) [view diff] case mismatch in snippet view article find links to article

Infertility in Female Mice due to a Pituitary-Specific Knockout of the Insulin Receptor (IR)". Cell Metabolism. 12 (3): 295–305. doi:10.1016/j.cmet.2010.06

Cytochrome p450 family 19 subfamily a member 1 (638 words) [view diff] exact match in snippet view article find links to article

polycystic ovary syndrome in caucasian women with a marker at the insulin receptor gene locus". J. Clin. Endocrinol. Metab. 86 (1): 446–9. doi:10.1210/jcem

Infertility in polycystic ovary syndrome (1,734 words) [view diff] case mismatch in snippet view article find links to article

Infertility in Female Mice due to a Pituitary-Specific Knockout of the Insulin Receptor (IR)". Cell Metabolism. 12 (3): 295–305. doi:10.1016/j.cmet.2010.06

Glutamate dehydrogenase 1 (3,043 words) [view diff] exact match in snippet view article find links to article

autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene". Diabetes. 53 (6): 1592–8. doi:10.2337/diabetes.53.6.1592. PMID 15161766

OCC-1 (1,147 words) [view diff] exact match in snippet view article find links to article

57 (3): 446–50. doi:10.1006/geno.1999.5791. PMID 10329014. "IRS4 – Insulin receptor substrate 4 – Homo sapiens (Human) – IRS4 gene & protein". Uniprot

Insulin resistance (6,297 words) [view diff] exact match in snippet view article find links to article

placental growth factor, which interferes with the interaction between insulin receptor substrate (IRS) and PI3K. This concept forms the basis of the adjustable

GIPC1 (1,893 words) [view diff] exact match in snippet view article find links to article

tail of the insulin-like growth factor-1 receptor but not with the insulin receptor". J. Biol. Chem. 276 (36): 33419–27. doi:10.1074/jbc.M104509200. PMID 11445579

BCAR1 (2,861 words) [view diff] exact match in snippet view article find links to article

receptor signaling pathway G protein-coupled receptor signaling pathway insulin receptor signaling pathway neurotrophin TRK receptor signaling pathway epidermal

EIF4EBP1 (2,696 words) [view diff] exact match in snippet view article find links to article

translational initiation of linear mRNA regulation of translation insulin receptor signaling pathway cellular response to dexamethasone stimulus G1/S

RPE65 (2,862 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum endoplasmic reticulum membrane Biological process insulin receptor signaling pathway response to light stimulus response to stimulus retinol

Phosphoinositide-dependent kinase-1 (2,127 words) [view diff] exact match in snippet view article find links to article

activity nucleotide binding protein kinase activity phospholipase binding insulin receptor binding 3-phosphoinositide-dependent protein kinase activity protein

Bcl-2 (4,868 words) [view diff] exact match in snippet view article find links to article

Tsujimoto Y, Kadowaki T, Hirai H (February 2000). "Association of insulin receptor substrate proteins with Bcl-2 and their effects on its phosphorylation

Signal transduction (7,624 words) [view diff] exact match in snippet view article find links to article

binds ligands; examples include growth factor receptors such as the insulin receptor. To perform signal transduction, RTKs need to form dimers in the plasma

Alexei Kharitonenkov (2,468 words) [view diff] exact match in snippet view article find links to article

"Adapter function of protein-tyrosine phosphatase 1D in insulin receptor/insulin receptor substrate-1 interaction". The Journal of Biological Chemistry

Apc, wnt signaling pathway regulator (617 words) [view diff] exact match in snippet view article find links to article

Wnt signaling pathway Wnt signaling pathway protein deubiquitination insulin receptor signaling pathway positive regulation of cell death protein homooligomerization

NCK1 (3,450 words) [view diff] exact match in snippet view article find links to article

signaling pathway positive regulation of neuron projection development negative regulation of insulin receptor signaling pathway Sources:Amigo / QuickGO

SOS1 (3,595 words) [view diff] exact match in snippet view article find links to article

regulation of pro-B cell differentiation hair follicle development insulin receptor signaling pathway roof of mouth development heart trabecula morphogenesis

CSNK2B (2,258 words) [view diff] exact match in snippet view article find links to article

Tanasijevic MJ, Myers MG, Thoma RS, et al. (1993). "Phosphorylation of the insulin receptor substrate IRS-1 by casein kinase II". J. Biol. Chem. 268 (24): 18157–66

PLCG1 (3,828 words) [view diff] no match in snippet view article find links to article

AJ (February 1996). "A Grb2-associated docking protein in EGF- and insulin-receptor signalling". Nature. 379 (6565): 560–4. Bibcode:1996Natur.379..560H

Daf-16 (3,033 words) [view diff] case mismatch in snippet view article find links to article

PMID 25383666. Boucher, Jérémie; Kleinridders, André; Kahn, C. Ronald (2014). "Insulin Receptor Signaling in Normal and Insulin-Resistant States". Cold Spring Harbor

RELA (6,578 words) [view diff] exact match in snippet view article find links to article

substance Fc-epsilon receptor signaling pathway negative regulation of insulin receptor signaling pathway defense response to virus positive regulation of

Myostatin (5,322 words) [view diff] exact match in snippet view article find links to article

transcription, DNA-templated response to gravity negative regulation of insulin receptor signaling pathway skeletal muscle tissue regeneration skeletal muscle

Hagit Eldar-Finkelman (1,114 words) [view diff] exact match in snippet view article find links to article

Eldar-Finkelman Eldar-Finkelman, H.; Krebs, E. G. (1997). "Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action".

NDEL1 (2,014 words) [view diff] exact match in snippet view article find links to article

cytoskeleton organization central nervous system neuron axonogenesis insulin receptor signaling pathway establishment of mitotic spindle orientation microtubule

Metformin (13,772 words) [view diff] exact match in snippet view article find links to article

IG, Brosseau R (October 1986). "Mechanism of action of metformin: insulin receptor and postreceptor effects in vitro and in vivo". The Journal of Clinical

Lipid raft (6,643 words) [view diff] exact match in snippet view article find links to article

signalling, B cell antigen receptor signalling, EGF receptor signalling, insulin receptor signalling and so on. In order to illustrate these principles, detailed

BAG3 (3,610 words) [view diff] no match in snippet view article find links to article

AJ (February 1996). "A Grb2-associated docking protein in EGF- and insulin-receptor signalling". Nature. 379 (6565): 560–4. Bibcode:1996Natur.379..560H

Free fatty acid receptor 3 (6,096 words) [view diff] exact match in snippet view article find links to article

hormone secretion signal transduction G protein-coupled receptor signaling pathway regulation of insulin receptor signaling pathway Sources:Amigo / QuickGO

PAK1 (5,251 words) [view diff] exact match in snippet view article find links to article

signaling cascade regulation of MAPK cascade positive regulation of insulin receptor signaling pathway cellular response to DNA damage stimulus cell migration

NEDD4 (3,414 words) [view diff] exact match in snippet view article find links to article

insulin-like growth factor (IGF-1) signalling by regulating the amount of insulin receptor (IR) and insulin-like growth factor 1 receptor (IGF-1R) on the cell

SR protein (3,445 words) [view diff] exact match in snippet view article find links to article

A1 and hnRNP F modulate the alternative splicing of exon 11 of the insulin receptor gene". PLOS ONE. 6 (11): e27869. Bibcode:2011PLoSO...627869T. doi:10

Trans fat (13,799 words) [view diff] exact match in snippet view article find links to article

with insulin resistance, with evidence that there is impaired post-insulin receptor binding signal transduction." Liver dysfunction: Trans fats are metabolized

Fat (15,005 words) [view diff] exact match in snippet view article find links to article

with insulin resistance, with evidence that there is impaired post-insulin receptor binding signal transduction." Infertility in women: One 2007 study

Christina, Queen of Sweden (14,928 words) [view diff] exact match in snippet view article find links to article

androgen hormone levels, and abdominal obesity due to the hormone insulin receptor defects. Buckley suggested that her low comprehension of the need for

Opioid use disorder (12,649 words) [view diff] exact match in snippet view article find links to article

to mediate opioid-induced withdrawal symptoms via downregulation of insulin receptor substrate 2 (IRS2), protein kinase B (AKT), and mechanistic target

CSRP3 (4,114 words) [view diff] exact match in snippet view article find links to article

transcription, DNA-templated inflammatory response heart development insulin receptor signaling pathway T-tubule organization glucose homeostasis protein

MAP4K4 (3,301 words) [view diff] exact match in snippet view article find links to article

PMID 7926300. S2CID 31871606. Skolnik EY, Marcusohn J (1996). "Inhibition of insulin receptor signaling by TNF: potential role in obesity and non-insulin-dependent

Bridget Carragher (1,948 words) [view diff] exact match in snippet view article find links to article

Strickland, C; Potter, CS; Carragher, B (2018). "Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis". Nature. 556 (7699):

Major facilitator superfamily (5,029 words) [view diff] exact match in snippet view article find links to article

Olefsky JM (October 1991). "Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients

Genetics of aging (2,249 words) [view diff] exact match in snippet view article find links to article

Epstein D, Tu MP, Yin CM, Garofalo RS (1988). "A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function"

Timeline of aging research (17,254 words) [view diff] exact match in snippet view article find links to article

pluripotent cells. 2007 Extension of mouse lifespan via deletion of insulin receptor in the brain. 2007 The book Ending Aging written by Aubrey de Grey

Congenital hyperinsulinism (9,329 words) [view diff] exact match in snippet view article find links to article

somatostatin receptor 5 agonist, and an allosteric inhibitor of the insulin receptor. The outcomes of individuals with HI are affected by the disease