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searching for Protein design 66 found (390 total)

Fusion protein (2,305 words) [view diff] exact match in snippet view article find links to article

Novel recombinant technologies have made it possible to improve fusion protein design for use in fields as diverse as biodetection, paper and food industries

IVX-411 (151 words) [view diff] case mismatch in snippet view article find links to article

trial in Australia. It was originally developed at the Institute of Protein Design (IPD) and the University of Washington School of Medicine, both based

Skycovione (764 words) [view diff] case mismatch in snippet view article find links to article

vaccine candidate developed by SK Bioscience and the Institute for Protein Design of the University of Washington, It is South Korea's first homegrown

William DeGrado (1,706 words) [view diff] exact match in snippet view article find links to article

Pharmaceutical Chemistry. As an early pioneer of protein design, he coined the term de novo protein design. He is also active in discovery of small molecule

In silico (1,439 words) [view diff] exact match in snippet view article find links to article

Validation of taxonomic assignment steps in herbivore metagenomics study. Protein design. One example is RosettaDesign, a software package under development

Rovelizumab (476 words) [view diff] case mismatch in snippet view article find links to article

successful. Among them are Genentech's erlizumab, and two drugs developed by Protein Design Labs and Centocor. Although trials in humans have not gone well, the

PDL BioPharma (588 words) [view diff] case mismatch in snippet view article find links to article

PDL BioPharma (known as Protein Design Labs prior to 2006) is a publicly traded American holding company that since 2008 manages patents and other intellectual

Carboxypeptidase A2 (678 words) [view diff] exact match in snippet view article find links to article

B, Callender D, et al. (2003). "A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins"

FoldX (695 words) [view diff] exact match in snippet view article find links to article

FoldX is a protein design algorithm that uses an empirical force field. It can determine the energetic effect of point mutations as well as the interaction

Tanja Kortemme (378 words) [view diff] exact match in snippet view article find links to article

has been recognized for outstanding contributions in computational protein design, including energy functions, sampling algorithms, and molecules to rewire

Apyrase (219 words) [view diff] exact match in snippet view article find links to article

Apyrase structure and protein design of human apyrase Identifiers Symbol Apyrase Pfam PF06079 InterPro IPR009283 SCOP2 1s1d / SCOPe / SUPFAM Membranome

Daclizumab (1,629 words) [view diff] case mismatch in snippet view article find links to article

faster. Daclizumab was created by scientists at PDL BioPharma (called "Protein Design Labs" at that time) by humanizing the mouse mAb called anti-Tac, which

Anticalin (407 words) [view diff] exact match in snippet view article find links to article

Biopharmazeutische Wirkstoffe durch Protein-Design" [German Future Prize 2004: Anticalins – Biopharmaceutical agents by protein design] (in German). Stifterverband

Erlizumab (424 words) [view diff] case mismatch in snippet view article find links to article

them are Icos's rovelizumab (LeukArrest), and two drugs developed by Protein Design Labs and Centocor. Although trials in humans have not gone well, the

Erlizumab (424 words) [view diff] case mismatch in snippet view article find links to article

them are Icos's rovelizumab (LeukArrest), and two drugs developed by Protein Design Labs and Centocor. Although trials in humans have not gone well, the

CANT1 (483 words) [view diff] exact match in snippet view article find links to article

PMID 14702039. Dai J, Liu J, Deng Y, et al. (2004). "Structure and protein design of a human platelet function inhibitor". Cell. 116 (5): 649–59. doi:10

Markus J. Buehler (2,044 words) [view diff] exact match in snippet view article find links to article

versa, realizing a materialization of sonic information in biomaterials protein design. He developed the materiomusical compositional technique. In 2020, he

Pileup format (575 words) [view diff] case mismatch in snippet view article find links to article

numeric names: authors list (link) Accelrys (1998-10-02). "QUANTA: Protein Design. 3. Reading and Writing Sequence Data Files". Université de Montréal

NL-201 (388 words) [view diff] case mismatch in snippet view article find links to article

protein that was first computationally designed at the Institute of Protein Design (IPD), University of Washington. In November 2022, Neoleukin Therapeutics

Applications of evolution (893 words) [view diff] exact match in snippet view article find links to article

cell.2006.12.006. PMID 17190597. Jäckel C; Kast P; Hilvert D (2008). "Protein design by directed evolution". Annu Rev Biophys. 37: 153–73. doi:10.1146/annurev

Proteins@home (348 words) [view diff] exact match in snippet view article find links to article

Anne; Mignon, David; Simonson, Thomas (2008-05-29). "Computational protein design: software implementation, parameter optimization, and performance of

Coiled coil (3,860 words) [view diff] exact match in snippet view article find links to article

Plecs JJ, Tidor B, Alber T, Kim PS (November 1998). "High-resolution protein design with backbone freedom". Science. 282 (5393): 1462–1467. doi:10.1126/science

Coiled coil (3,860 words) [view diff] exact match in snippet view article find links to article

Plecs JJ, Tidor B, Alber T, Kim PS (November 1998). "High-resolution protein design with backbone freedom". Science. 282 (5393): 1462–1467. doi:10.1126/science

Lisa Jones (scientist) (732 words) [view diff] case mismatch in snippet view article

names: authors list (link) Jones, Lisa Michelle (4 August 2008). Using Protein Design to Understand the Role of Electrostatic Interactions on Calcium Binding

Irving–Williams series (655 words) [view diff] no match in snippet view article find links to article

study published in the journal Nature, researchers have reported a protein-design approach to overcome the Irving-Williams series restriction, allowing

Comparison of software for molecular mechanics modeling (379 words) [view diff] exact match in snippet view article find links to article

Wayback Machine FoldX I Yes Yes No No No No No No Energy calculations, protein design Proprietary, commercial or gratis CRG GROMACS No No Yes Yes No Yes I

Humanized antibody (1,787 words) [view diff] case mismatch in snippet view article find links to article

States, this software was developed, patented, and demonstrated, by Protein Design Labs, Inc. in Mountain View, California, in the 1980s and 1990s. Alemtuzumab

Humanized antibody (1,787 words) [view diff] case mismatch in snippet view article find links to article

States, this software was developed, patented, and demonstrated, by Protein Design Labs, Inc. in Mountain View, California, in the 1980s and 1990s. Alemtuzumab

Dek Woolfson (1,309 words) [view diff] exact match in snippet view article find links to article

structures and functions of proteins; and also the challenge of rational protein design and how this can be applied in synthetic biology and biotechnology.

Cyclic peptide (742 words) [view diff] case mismatch in snippet view article find links to article

PMC 8997995. PMID 35406720. Jensen, Knud (2009-09-01). Peptide and Protein Design for Biopharmaceutical Applications. John Wiley & Sons. ISBN 9780470749715

Charity Engine (732 words) [view diff] case mismatch in snippet view article find links to article

UK. 3 October 2016. Retrieved 2019-09-22. "The Power of Charity For Protein Design". University of Washington. Retrieved 2014-08-15. "Big data (and volunteers)

Icos (4,327 words) [view diff] case mismatch in snippet view article find links to article

a treatment for solid tumors. In October 2003, Icos partnered with Protein Design Labs to manufacture their M200 antibody. After Icos's experimental drugs

Gary K. Michelson (2,815 words) [view diff] case mismatch in snippet view article find links to article

the USC Michelson Center for Convergent Bioscience, the Institute for Protein Design at the University of Washington,and the California Institute of Immunology

Spectral centroid (465 words) [view diff] case mismatch in snippet view article find links to article

Garcia, Angel E.; Weiss, Thomas M.; Snell, Edward H. (2022-02-17). "From Protein Design to the Energy Landscape of a Cold Unfolding Protein". The Journal of

Catherine Dulac (1,120 words) [view diff] case mismatch in snippet view article find links to article

"2021 Breakthrough Prize Winners Announced: Researcher Who Developed Protein Design Technology Awarded $3 Million". Forbes. Retrieved September 10, 2020

Complementarity plot (1,357 words) [view diff] exact match in snippet view article find links to article

charges within protein interiors. It is useful in homology modeling and protein design. A version of the plot (CPint) has also been built and made available

Sequence space (evolution) (1,410 words) [view diff] exact match in snippet view article

MH; Davidson, AR; Sauer, RT (Feb 1996). "Sequence space, folding and protein design". Current Opinion in Structural Biology. 6 (1): 3–10. doi:10

Signature BioScience (1,122 words) [view diff] case mismatch in snippet view article find links to article

Robert J. Zimmerman succeeded Mark McDade, who left Signature to go to Protein Design Labs. Zimmerman became the President and a member of the Board of Directors

Synthetic biology (18,308 words) [view diff] exact match in snippet view article find links to article

Sheehan MM, Fry BA, et al. (December 2013). "Elementary tetrahelical protein design for diverse oxidoreductase functions". Nature Chemical Biology. 9 (12):

Open Philanthropy (2,151 words) [view diff] case mismatch in snippet view article find links to article

Security. $11.3 million to the University of Washington’s Institute for Protein Design to develop a universal flu vaccine. About $23 million to the Effective

Elizabeth D. Getzoff (456 words) [view diff] exact match in snippet view article find links to article

protein crystallography, computational and computer graphics analysis, protein design cycles, small angle X-ray scattering, biochemical and spectroscopic

Michael Levitt (2,515 words) [view diff] case mismatch in snippet view article find links to article

Boards of the following companies: Dupont Merck Pharmaceuticals, AMGEN, Protein Design Labs, Affymetrix, Molecular Applications Group, 3D Pharmaceuticals,

California Institute of Technology (13,654 words) [view diff] exact match in snippet view article find links to article

(RFID), semiconductors, hyperspectral imaging, electronic devices, protein design, solid state amplifiers and many more. Companies such as Quora, Contour

Hemoprotein (2,446 words) [view diff] exact match in snippet view article find links to article

Sheehan MM, Fry BA, et al. (December 2013). "Elementary tetrahelical protein design for diverse oxidoreductase functions". Nature Chemical Biology. 9 (12):

Alfonso Valencia (2,361 words) [view diff] case mismatch in snippet view article find links to article

DeepMind's AlphaFold 2 algorithm in 2020. In 1994 Valencia formed the Protein Design Group at the Spanish National Center for Biotechnology (CNB). He was

James A. Wells (2,036 words) [view diff] exact match in snippet view article find links to article

(cassette mutagenesis, alanine scanning, protein phage display) and protein design principles ("hot-spots" in protein interfaces, additivity of mutational

Alpidem (4,669 words) [view diff] no match in snippet view article find links to article

Mokrov GV, Deeva OA, Gudasheva TA (2021). "The Ligands of Translocator Protein: Design and Biological Properties". Current Pharmaceutical Design. 27 (2):

Non-proteinogenic amino acids (2,862 words) [view diff] case mismatch in snippet view article find links to article

(2006). "Design and Synthesis of β-Peptides With Biological Activity". Protein Design. Methods in Molecular Biology. Vol. 340. pp. 95–109. doi:10.1385/1-59745-116-9:95

Statistical coupling analysis (1,133 words) [view diff] exact match in snippet view article find links to article

Statistical coupling analysis has also been used as a basis for computational protein design. In 2005, Socolich et al. used an SCA for the WW domain to create artificial

Evolution (24,705 words) [view diff] case mismatch in snippet view article find links to article

S2CID 278993. Jäckel, Christian; Kast, Peter; Hilvert, Donald (June 2008). "Protein Design by Directed Evolution". Annual Review of Biophysics. 37: 153–173. doi:10

Translational bioinformatics (2,815 words) [view diff] exact match in snippet view article find links to article

also exist in the research of drugs and biomarkers, genomic medicine, protein design metagenomics, infectious disease discovery, data curation, literature

Expanded genetic code (9,128 words) [view diff] exact match in snippet view article find links to article

2015). "Biocontainment of genetically modified organisms by synthetic protein design". Nature. 518 (7537): 55–60. Bibcode:2015Natur.518...55M. doi:10.1038/nature14121

List of biophysicists (2,490 words) [view diff] exact match in snippet view article find links to article

received a Nobel Prize David Baker — Protein structure prediction; protein design; Rosetta software Adriaan (Ad) Bax (Dutch-born American, 1956–) — development

Erin Schuman (1,161 words) [view diff] case mismatch in snippet view article find links to article

PMID 22578497. "Reinterpreting the Genetic Code: Non-Canonical Amino Acids in Protein Design, Evolution and Analysis - Caltech Tirrell Lab". tirrell-lab.caltech

Schellman loop (1,139 words) [view diff] exact match in snippet view article find links to article

(2002-03-01). "A test of proposed rules for helix capping: Implications for protein design". Protein Science. 11 (3): 516–521. doi:10.1110/ps.39802. ISSN 1469-896X

Translocator protein (3,181 words) [view diff] no match in snippet view article find links to article

Mokrov GV, Deeva OA, Gudasheva TA (2021). "The Ligands of Translocator Protein: Design and Biological Properties". Current Pharmaceutical Design. 27 (2):

Victor Muñoz (biochemist) (521 words) [view diff] case mismatch in snippet view article

for Science and Engineering, USA "Protein Folding, Misfolding and Aggregation", RSC Publishing PRODESTECH - Protein Design Technologies Consortium v t e

Paula Booth (706 words) [view diff] case mismatch in snippet view article find links to article

"A Basis Set of de Novo Coiled-Coil Peptide Oligomers for Rational Protein Design and Synthetic Biology". ACS Synthetic Biology. 1 (6): 240–250. doi:10

Clara Wu Tsai (1,736 words) [view diff] case mismatch in snippet view article find links to article

Presbyterian Hospital. She serves on the advisory board for the Institute of Protein Design at the University of Washington. She is also on the REFORM Alliance

Krishna Kumar (chemist) (839 words) [view diff] case mismatch in snippet view article

79 (49), p. 35. Yoder, N. C.; Kumar, K. "Fluorinated Amino Acids in Protein Design and Engineering." Chem. Soc. Rev. 2002, 31, 335-341. Bilgicer B, Kumar

List of filename extensions (M–R) (1,430 words) [view diff] case mismatch in snippet view article

Description Language". Retrieved 2020-09-18. Accelrys (1998-10-02). "QUANTA: Protein Design. 3. Reading and Writing Sequence Data Files". Université de Montréal

2023 in science (44,458 words) [view diff] exact match in snippet view article find links to article

is demonstrated (10 July), a performant open source AI software for protein design (RFdiffusion) is introduced (11 July), metaresearchers show that AI

List of University of California, Berkeley alumni (9,884 words) [view diff] case mismatch in snippet view article find links to article

intervention in human diseases" biochemist, head of the Institute for Protein Design, professor of biochemistry at the University of Washington Harry F.

List of biochemists (10,432 words) [view diff] exact match in snippet view article find links to article

1955). American pharmaceutical chemist at UC San Francisco, known for protein design, synthesis of peptidomimetics, and characterizing membrane-active peptides

Riccardo Cortese (2,833 words) [view diff] exact match in snippet view article find links to article

PMID 7534789. S2CID 42441516. Martin, Franck; et al. (1996). "Coupling protein design and in vitro selection strategies: improving specificity and affinity

Natural scientific research in Canada (20,478 words) [view diff] exact match in snippet view article find links to article

nano-scaled materials for chemical reactions at semiconductor surfaces, protein design, genetic engineering and nanoelectromechanical systems. Of particular