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searching for STAT5 45 found (97 total)

alternate case: sTAT5

Aurintricarboxylic acid (522 words) [view diff] exact match in snippet view article find links to article

enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases

CRLF2 (600 words) [view diff] exact match in snippet view article find links to article

capable of stimulating cell proliferation through activation of STAT3, STAT5 and JAK2 pathways and is implicated in the development of the hematopoietic

Interleukin-7 receptor-α (840 words) [view diff] exact match in snippet view article find links to article

lymphoblastic leukemia cells and murine BAF3 cells involves activation of STAT1 and STAT5 mediated via the interleukin-7 receptor alpha chain". Leukemia. 10 (8):

PTPN6 (2,292 words) [view diff] exact match in snippet view article find links to article

(January 2000). "Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation". J. Biol. Chem. 275 (1): 599–604. doi:10.1074/jbc

Stephanie S. Watowich (843 words) [view diff] exact match in snippet view article find links to article

and signaling functions, as well as roles for the signal transducers STAT5 and STAT5 in erythropoiesis. In her final year as director, Watowich was the

Philadelphia chromosome (3,538 words) [view diff] exact match in snippet view article find links to article

models to downregulate downstream cytokine signaling by silencing STAT3 and STAT5 transcription activation (appelmann et al.). The interaction between JAK2

Interleukin-15 receptor (690 words) [view diff] exact match in snippet view article find links to article

activation that subsequently phosphorylates STAT3 via the β chain and JAK3/STAT5 activation via its γ chain. Once tyrosine-phosphorylated, STAT transcription

PAK2 (2,164 words) [view diff] exact match in snippet view article find links to article

Paxillin phosphorylation at S272 and S274 activates ADAM10 protease, and STAT5 phosphorylation at S779 modulates BCL-ABL-mediated leukemogenesis. PAK2

HCK (2,331 words) [view diff] exact match in snippet view article find links to article

phosphorylate downstream molecules such as Bcr/Abl, PI3K/AKT, MAPK/ERK or STAT5 which then participate in myeloid cell polarization, proliferation and migration

PTPN11 (4,300 words) [view diff] exact match in snippet view article find links to article

(January 2000). "Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation". J. Biol. Chem. 275 (1): 599–604. doi:10.1074/jbc

Bcl-xL (918 words) [view diff] case mismatch in snippet view article find links to article

order to survive and become red cells. Bcl-xL promoter contains GATA-1 and Stat5 sites. This protein accumulates throughout the differentiation, ensuring

List of MeSH codes (D12.776.930) (1,091 words) [view diff] case mismatch in snippet view article

The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

GPR126 (1,572 words) [view diff] exact match in snippet view article find links to article

angiogenesis by modulating VEGF receptor 2 (VEGFR2) expression through STAT5 and GATA2 in endothelial cells. Mouse models have shown GPR126 deletion

Cyclin D (4,605 words) [view diff] exact match in snippet view article find links to article

growth factor or oncogene induced expression by Src, Ras, ErbB2, STAT3, STAT5, impaired protein degradation, or chromosomal translocation. Gene amplification

Dedicator of cytokinesis protein 11 (966 words) [view diff] exact match in snippet view article find links to article

to abnormal actin cytoskeleton remodeling, impaired CDC42 activity and STAT5 activation, and associated with early-onset autoimmunity. GRCh38: Ensembl

DUSP3 (979 words) [view diff] exact match in snippet view article find links to article

edge: selective tyrosine dephosphorylation of interferon-activated nuclear STAT5 by the VHR phosphatase". J. Immunol. 179 (6): 3402–6. doi:10.4049/jimmunol

Lestaurtinib (1,584 words) [view diff] exact match in snippet view article find links to article

2008). "Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients

Growth hormone receptor (1,925 words) [view diff] exact match in snippet view article find links to article

(December 1999). "SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms". The Journal of Biological Chemistry.

IL2RB (1,698 words) [view diff] exact match in snippet view article find links to article

Bouvier G, Bertoglio J (January 2000). "Association of STAT1, STAT3 and STAT5 proteins with the IL-2 receptor involves different subdomains of the IL-2

Tyrosin-protein kinase Lck (4,466 words) [view diff] exact match in snippet view article find links to article

(January 2000). "Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation". The Journal of Biological Chemistry. 275 (1):

Anne Rosenberg (1,716 words) [view diff] case mismatch in snippet view article find links to article

aberrations in breast cancer. Together, they also demonstrated that the loss of Stat5 in estrogen-receptor-positive breast cancer is associated with increased

STAP2 (571 words) [view diff] exact match in snippet view article find links to article

et al. (2005). "Physical and functional interactions between STAP-2/BKS and STAT5". J. Biol. Chem. 280 (9): 8188–96. doi:10.1074/jbc.M411692200. hdl:2115/28113

Lenzilumab (1,120 words) [view diff] case mismatch in snippet view article find links to article

is enhanced by granulocyte-macrophage colony-stimulating factor via Jak2-Stat5 signaling and inhibited by atorvastatin in human monocytic U937 cells".

PPP2R1B (1,258 words) [view diff] case mismatch in snippet view article find links to article

"Involvement of protein phosphatase 2A in the interleukin-3-stimulated Jak2-Stat5 signaling pathway". Journal of Interferon & Cytokine Research. 21 (6): 369–78

MAPK1 (2,322 words) [view diff] case mismatch in snippet view article find links to article

"Growth hormone (GH) induces the formation of protein complexes involving Stat5, Erk2, Shc and serine phosphorylated proteins". Mol. Cell. Endocrinol. 166

Thymic stromal lymphopoietin (2,415 words) [view diff] case mismatch in snippet view article find links to article

Trobridge PA, Farr AG, Levin SD, Ziegler SF (December 1999). "Requirement for stat5 in thymic stromal lymphopoietin-mediated signal transduction". Journal of

Interleukin 3 (2,624 words) [view diff] exact match in snippet view article find links to article

progenitors, basophils, and eosinophils. IL-3/Receptor complex induces JAK2/STAT5 cell signalization pathway. It can stimulate transcription factor c‑myc

SH2B1 (1,468 words) [view diff] exact match in snippet view article find links to article

fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation". J Biol Chem. 277 (18): 15962–70. doi:10.1074/jbc.M102777200

N-myc-interactor (1,163 words) [view diff] case mismatch in snippet view article find links to article

John S, Berg M, Leonard WJ (Mar 1999). "Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling". Cell. 96 (1): 121–30

KIAA1958 (638 words) [view diff] case mismatch in snippet view article find links to article

migration of the metastatic cancer cells. KIAA1958 was also overexpressed in Stat5/ab and stat 3 which are transcription factors reported to be critical for

Checkpoint inhibitor (2,093 words) [view diff] exact match in snippet view article find links to article

Surprisingly there was no changes in activity of Cish's purported target, STAT5. CISH knock out in T cells increased PD-1 expression and the adoptive transfer

Oncostatin M (4,317 words) [view diff] exact match in snippet view article find links to article

M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway". EMBO J. 15 (5): 1055–63. doi:10.1002/j.1460-2075.1996.tb00443

Heat shock protein 90kDa alpha (cytosolic), member A1 (8,175 words) [view diff] exact match in snippet view article

cells the growth hormone prolactin induces HSP90AA1 expression through STAT5. NF-κB or RELA also induces HSP90AA1 expression possibly explaining the

LYN (3,807 words) [view diff] case mismatch in snippet view article find links to article

with the erythropoietin receptor and may play a role in activation of the Stat5 pathway". Blood. 91 (10): 3734–45. doi:10.1182/blood.V91.10.3734. PMID 9573010

Weiping Zou (1,120 words) [view diff] exact match in snippet view article find links to article

since its publication. Zhou, J. et al. The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity. Nat Immunol, doi:10

Cyclin D1 (5,694 words) [view diff] exact match in snippet view article find links to article

(March 1999). "Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells". The

Adoptive cell transfer (4,028 words) [view diff] exact match in snippet view article find links to article

Surprisingly there was no changes in activity of Cish's purported target, STAT5. Thus Cish represents a new class of T-cell intrinsic immunologic checkpoints

CRKL (3,165 words) [view diff] exact match in snippet view article find links to article

M, Shimamura S, Motoyoshi K (November 1998). "Association of CrkL with STAT5 in hematopoietic cells stimulated by granulocyte-macrophage colony-stimulating

John J. O'Shea (1,292 words) [view diff] exact match in snippet view article find links to article

the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5". Nature Immunology. 12 (3): 247–54. doi:10.1038/ni.1995. PMC 3182404. PMID 21278738

List of MeSH codes (D12.776.476) (1,240 words) [view diff] case mismatch in snippet view article

024.421.400 – stat4 transcription factor MeSH D12.776.476.024.421.500 – stat5 transcription factor MeSH D12.776.476.024.421.600 – stat6 transcription

Spinal muscular atrophy (9,953 words) [view diff] exact match in snippet view article find links to article

and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway". The Journal of Clinical Investigation. 121 (8): 3042–50. doi:10

List of MeSH codes (D12.644) (5,787 words) [view diff] case mismatch in snippet view article

024.342.400 – stat4 transcription factor MeSH D12.644.360.024.342.500 – stat5 transcription factor MeSH D12.644.360.024.342.600 – stat6 transcription

List of MeSH codes (D12.776.157) (4,484 words) [view diff] case mismatch in snippet view article

057.186.400 – stat4 transcription factor MeSH D12.776.157.057.186.500 – stat5 transcription factor MeSH D12.776.157.057.186.600 – stat6 transcription

C9orf85 (1,317 words) [view diff] exact match in snippet view article find links to article

translocator-like, homodimer 1.000 MZF1 Myeloid zinc finger protein 0.992 STAT STAT5: signal transducer and activator of transcription 5 0.944 ETSF ETS-like

ISLR (4,000 words) [view diff] exact match in snippet view article find links to article

on 21 February 2020. Retrieved 2 August 2020. "ELM - Detail for LIG_SH2_STAT5". elm.eu.org. Archived from the original on 22 February 2020. Retrieved