language:
Find link is a tool written by Edward Betts.Longer titles found: Directed evolution (transhumanism) (view)
searching for Directed evolution 125 found (235 total)
alternate case: directed evolution
Teleology in biology
(4,036 words)
[view diff]
case mismatch in snippet
view article
find links to article
ISSN 0305-0270. Askland, Andrew (2011). "The Misnomer of Transhumanism as Directed Evolution" (PDF). International Journal of Emerging Technologies and SocietyBryan Roth (659 words) [view diff] exact match in snippet view article find links to article
identification of new probes and tools to detect GPCRs, obtained through directed evolution in animal cells, developing receptors activated solely by a syntheticRibosome display (966 words) [view diff] exact match in snippet view article find links to article
be transformed after any diversification step. This allows facile directed evolution of binding proteins over several generations. A prerequisite for theThreose nucleic acid (1,204 words) [view diff] exact match in snippet view article find links to article
incoming TNA nucleotide triphosphate and support the need for further directed evolution experiments to create TNA polymerases with improved activity. TheMonobody (1,490 words) [view diff] exact match in snippet view article find links to article
portions of the FN3 scaffold are diversified using molecular display and directed evolution technologies such as phage display, mRNA display and yeast surfaceTheodor Eimer (817 words) [view diff] exact match in snippet view article find links to article
German zoologist. He was a popularizer of orthogenesis, a form of directed evolution through mutations that made use of Lamarckian principles. Eimer wasOncolytic adenovirus (4,209 words) [view diff] exact match in snippet view article find links to article
currently in development is ColoAd1. It was created using a process of “directed evolution”. This involves the creation of new viral variants or serotypes specificallyHuimin Zhao (271 words) [view diff] exact match in snippet view article find links to article
Carl R. Woese Institute for Genomic Biology. His research focuses on directed evolution, metabolic engineering, bioinformatics and high throughput technologiesNicholas Turner (chemist) (1,060 words) [view diff] exact match in snippet view article
His group combine enzyme discovery with protein engineering and directed evolution methods in order to develop biocatalysts with tailored propertiesSNAP-tag (1,001 words) [view diff] exact match in snippet view article find links to article
O-6-methylguanine-DNA methyltransferase (MGMT) gene. SNAP-tag was obtained using a directed evolution strategy, leading to a hAGT variant that accepts O6-benzylguanineMolecular genetics (3,842 words) [view diff] case mismatch in snippet view article find links to article
Retrieved 2023-10-16. "Selection versus Screening in Directed Evolution", Directed Evolution of Selective Enzymes, John Wiley & Sons, Ltd, 2016, ppMulticellular organism (4,643 words) [view diff] exact match in snippet view article find links to article
identified by directed evolution. More recently (2024), snowflake yeast were subject to over 3,000 generations of further directed evolution, forming macroscopicSite-directed mutagenesis (2,973 words) [view diff] exact match in snippet view article find links to article
Steinberg, Barrett E. (16 April 2020). "SMOOT libraries and phage-induced directed evolution of Cas9 to engineer reduced off-target activity". PLOS ONE. 15 (4):George I. Mavrodes (508 words) [view diff] exact match in snippet view article find links to article
understanding of evolution holds that although evolution occurred, God still directed evolution. Evolution is merely the tool of God's design. Evolution, and evenIn vitro compartmentalization (2,195 words) [view diff] exact match in snippet view article find links to article
007. PMID 17055094. Ghadessy FJ, Ong JL, Holliger P (April 2001). "Directed evolution of polymerase function by compartmentalized self-replication". ProceedingsInvertebrate (4,736 words) [view diff] exact match in snippet view article find links to article
and vertebrates were closer than invertebrates were. Although goal-directed evolution has been abandoned, the distinction of invertebrates and vertebratesTheistic evolution (7,566 words) [view diff] exact match in snippet view article find links to article
different positions from the 1890s to the 1920s: "Orthogenesis" (goal-directed evolution), "nomogenesis" (evolution according to fixed law), "emergent evolution"Cambridge Antibody Technology (8,495 words) [view diff] exact match in snippet view article find links to article
L; Minter, RR (2006). "Probing a protein-protein interaction by directed evolution". Proc Natl Acad Sci USA. 103 (20): 7619–24. Bibcode:2006PNAS..103Ulrich Schwaneberg (839 words) [view diff] exact match in snippet view article find links to article
Institute for Interactive Materials in Aachen. He specializes in directed evolution of proteins for material science applications and on the developmentFluorescence-activating and absorption-shifting tag (943 words) [view diff] exact match in snippet view article find links to article
protein, was engineered from the photoactive yellow protein (PYP) by directed evolution. It was reported for the first time in 2016 by researchers from EcoleBeta-2 microglobulin (2,117 words) [view diff] case mismatch in snippet view article find links to article
HLA-G 2esv: Structure of the HLA-E-VMAPRTLIL/KK50.4 TCR complex 2f53: Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramaticallyGaia hypothesis (9,369 words) [view diff] case mismatch in snippet view article find links to article
version of the hypothesis has been called "influential Gaia" in "Directed Evolution of the Biosphere: Biogeochemical Selection or Gaia?" by Andrei G.Β-Galactosidase (2,994 words) [view diff] exact match in snippet view article find links to article
1981). "Changes in the substrate specificities of an enzyme during directed evolution of new functions". Biochemistry. 20 (14): 4042–9. doi:10.1021/bi00517a015Broad Institute (2,604 words) [view diff] exact match in snippet view article find links to article
Institute, the inventor of DNA-templated synthesis, phage-assisted directed evolution and Cas9/CRISPR base-editing. Stuart Schreiber is director of theEnzyme (9,774 words) [view diff] exact match in snippet view article find links to article
Eggert T (August 2004). "Enantioselective biocatalysis optimized by directed evolution". Current Opinion in Biotechnology. 15 (4): 305–313. doi:10.1016/jAeropyrum pernix (637 words) [view diff] exact match in snippet view article find links to article
of Aeropyrum pernix farnesylgeranyl diphosphate synthase (Fgs) by directed evolution". Protein Engineering Design & Selection. 17 (11): 771–777. doi:10Edward F. Fritsch (709 words) [view diff] no match in snippet view article find links to article
(EPO) gene. Fritsch then joined Phylos, Inc. to utilize a in vitro, directed-evolution technology to discover new protein therapeutics, eventually becomingBaeyer–Villiger oxidation (2,981 words) [view diff] case mismatch in snippet view article find links to article
Traditional Electronic Effects in Biocatalytic Baeyer–Villiger Reactions by Directed Evolution". Journal of the American Chemical Society. 140 (33): 10464–104722-Dehydro-3-deoxy-phosphogluconate aldolase (1,629 words) [view diff] case mismatch in snippet view article find links to article
amino acid sequences yet analogous symmetrical structure and folding. Directed Evolution KDPG aldolase has limited utility due to its high specificity forHLA-A (3,411 words) [view diff] case mismatch in snippet view article find links to article
PEPTIDE EXTENDING OUT ONE END OF A CLASS I MHC BINDING SITE 2f53: Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramaticallyLaccase (2,036 words) [view diff] case mismatch in snippet view article find links to article
of a Novel Bacterial Laccase and Improvement of Its Efficiency by Directed Evolution on Dye Degradation". Frontiers in Microbiology. 12: 633004. doi:10Inositol oxygenase (1,818 words) [view diff] exact match in snippet view article find links to article
numerous strategies including appendage of an N-terminal SUMO-tag, directed evolution and also the use of modular, synthetic scaffolds to increase its effectiveDNA methyltransferase (3,598 words) [view diff] exact match in snippet view article find links to article
recognition specificity of the EcoDam DNA-(adenine-N6)-methyltransferase by directed evolution". Journal of Molecular Biology. 395 (1): 79–88. doi:10.1016/j.jmbCope's rule (1,968 words) [view diff] exact match in snippet view article find links to article
this is usually a result of size varying pseudo-randomly rather than directed evolution. This does not fall into Cope's rule sensu stricto, but is consideredMichael Denton (738 words) [view diff] exact match in snippet view article find links to article
of organisms; he has proposed an evolutionary theory which is a "directed evolution" in his book Nature's Destiny (1998). Life, according to Denton, didStructuralism (biology) (2,353 words) [view diff] exact match in snippet view article
developmental constraints, led (solid blue arrows) to some form of directed evolution (orthogenesis), with or without invoking divine control (dotted blueMichael Denton (738 words) [view diff] exact match in snippet view article find links to article
of organisms; he has proposed an evolutionary theory which is a "directed evolution" in his book Nature's Destiny (1998). Life, according to Denton, didMRC Laboratory of Molecular Biology (3,832 words) [view diff] exact match in snippet view article find links to article
PMID 23741620. World2018-10-03T11:06:00+01:00, Chemistry. "Live blog: directed evolution takes chemistry Nobel prize". Chemistry World. Retrieved 23 FebruaryVirus (18,121 words) [view diff] exact match in snippet view article find links to article
A particular quality of viruses is that they can be tailored by directed evolution. The powerful techniques developed by life sciences are becoming theChristian fundamentalism (7,440 words) [view diff] exact match in snippet view article find links to article
the Bible, and others were comfortable teaching some forms of God-directed evolution. Riley and the more strident fundamentalists, however, associatedDouglas Youvan (974 words) [view diff] exact match in snippet view article find links to article
worked in the field of combinatorial mutagenesis which can be used for directed evolution of proteins, such as enzymes. At MIT, they discovered a pattern inTranshumanist politics (4,972 words) [view diff] exact match in snippet view article find links to article
original on June 14, 2012, The central transhumanist idea of self-directed evolution can be coupled with different political, philosophical and religiousCarbonic anhydrase (4,347 words) [view diff] exact match in snippet view article find links to article
CK, Bresson JA, Lakhapatri SL, Solis EO, et al. (November 2014). "Directed evolution of an ultrastable carbonic anhydrase for highly efficient carbon captureHigh-throughput screening (4,120 words) [view diff] exact match in snippet view article find links to article
Mazaleyrat, S. L. (2007). "Development of a screening platform for directed evolution using the reef coral fluorescent protein ZsGreen as a solubility reporter"Dependoparvovirus (843 words) [view diff] exact match in snippet view article find links to article
New York, US. Retrieved 4 May 2009. Excoffon, K; et al. (2009). "Directed evolution of adeno-associated virus to an infectious respiratory virus". ProceedingsHertz Foundation (1,984 words) [view diff] case mismatch in snippet view article find links to article
delivery platform 2011 Kevin Esvelt, A System for the Continuous Directed Evolution of Biomolecules 2011 Monika Schleier-Smith, Cavity-Enabled Spin SqueezingNeutral network (evolution) (2,783 words) [view diff] exact match in snippet view article
L; Kast, P; van Gunsteren, WF; Marlière, P; Hilvert, D (2013). "Directed evolution of a model primordial enzyme provides insights into the developmentPyrococcus woesei (318 words) [view diff] exact match in snippet view article find links to article
Ai-Sheng; Peng, Ri-He; Zhuang, Jing; Li, Xian; et al. (18 Sep 2007). "Directed evolution of a beta-galactosidase from Pyrococcus woesei resulting in increasedJane Glazebrook (744 words) [view diff] case mismatch in snippet view article find links to article
Casim. (February 2017-February 2019). Engineering Plant Immunity via Directed Evolution of Imm. USDA National Institute of Food & Agriculture. Glazebook,Transcription activator-like effector nuclease (3,147 words) [view diff] exact match in snippet view article find links to article
PMID 17603476. S2CID 22079561. Guo J, Gaj T, Barbas CF (July 2010). "Directed evolution of an enhanced and highly efficient FokI cleavage domain for zincHemoprotein (2,446 words) [view diff] exact match in snippet view article find links to article
Schneider P, Vind J, Svendsen A, Jones A, Pedersen AH (April 1999). "Directed evolution of a fungal peroxidase". Nature Biotechnology. 17 (4): 379–384. doi:10Green fluorescent protein (7,456 words) [view diff] case mismatch in snippet view article find links to article
PMC 5007177. PMID 27479328. Mattson S, Tran GN, Rodriguez EA (2023). "Directed Evolution of Fluorescent Proteins in Bacteria". In Sharma M (ed.). FluorescentCarl Nägeli (1,016 words) [view diff] exact match in snippet view article find links to article
Darwinism. He developed an "inner perfecting principle" which he believed directed evolution. He wrote that many evolutionary developments were nonadaptive andIslamic views on evolution (5,877 words) [view diff] no match in snippet view article find links to article
acceptance, albeit divinely designed. The movement actively promotes god-directed "evolution". Over the course of several decades the movement issued variousSeSaM-Biotech GmbH (882 words) [view diff] exact match in snippet view article find links to article
Retrieved April 24, 2017. Cheng, F.; Zhu, L.; Schwaneberg, U. (2015). "Directed evolution 2.0: improving and deciphering enzyme properties" (PDF). Chem. CommunKarl Ernst von Baer (2,798 words) [view diff] exact match in snippet view article find links to article
organisms. Baer believed in a teleological force in nature which directed evolution (orthogenesis). The term Baer's law is also applied to the unconfirmedAlfred Russel Wallace (14,212 words) [view diff] exact match in snippet view article find links to article
commented that this anticipated ideas about design in nature and directed evolution that would arise from religious traditions throughout the 20th centuryOn the Origin of Species (18,812 words) [view diff] exact match in snippet view article find links to article
tried to meet these objections in the fifth edition. Mivart supported directed evolution, and compiled scientific and religious objections to natural selectionPhytoene desaturase (neurosporene-forming) (217 words) [view diff] exact match in snippet view article
product specificity of Rhodobacter sphaeroides phytoene desaturase by directed evolution". The Journal of Biological Chemistry. 276 (44): 41161–4. doi:10.1074/jbcYersinia mollaretii (178 words) [view diff] exact match in snippet view article find links to article
Roccatano, Danilo; Haefner, Stefan; Schwaneberg, Ulrich (2011). "Directed evolution of a highly active Yersinia mollaretii phytase". Applied MicrobiologyGeranylfarnesyl diphosphate synthase (249 words) [view diff] exact match in snippet view article find links to article
of Aeropyrum pernix farnesylgeranyl diphosphate synthase (Fgs) by directed evolution". Protein Engineering, Design & Selection. 17 (11): 771–7. doi:10PON3 (901 words) [view diff] exact match in snippet view article find links to article
1038/nature01782. PMID 12853948. Aharoni A, Gaidukov L, Yagur S, et al. (2004). "Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression andIrish elk (6,374 words) [view diff] exact match in snippet view article find links to article
with smaller antlers, was taken as a prime example of orthogenesis (directed evolution), an evolutionary mechanism opposed to Darwinian evolution in whichHalohydrin dehalogenase (969 words) [view diff] exact match in snippet view article find links to article
dehalogenase from Arthrobacter sp. strain AD2, revealed by structure-guided directed evolution". Appl Environ Microbiol. 78 (8): 4051–4056. Bibcode:2012ApEnM..78Halohydrin dehalogenase (969 words) [view diff] exact match in snippet view article find links to article
dehalogenase from Arthrobacter sp. strain AD2, revealed by structure-guided directed evolution". Appl Environ Microbiol. 78 (8): 4051–4056. Bibcode:2012ApEnM..78Alternatives to Darwinian evolution (5,843 words) [view diff] exact match in snippet view article find links to article
arrows). Many of these theories led (blue arrows) to some form of directed evolution (orthogenesis), with or without invoking divine control (dotted blueDiapolycopene oxygenase (153 words) [view diff] exact match in snippet view article find links to article
synthesizing acyclic xanthophylls: combinatorial biosynthesis and directed evolution". Chemistry & Biology. 12 (4): 453–60. doi:10.1016/j.chembiol.2005Bicyclobutane (712 words) [view diff] exact match in snippet view article find links to article
Anabaena sphaerica (strain PCC 7120). The other group reported a directed evolution approach, whereby engineered heme protein was expressed in E. coliMosaic protein (621 words) [view diff] exact match in snippet view article find links to article
S2CID 24447528. Kolkman, Joost A.; Stemmer, Willem P. C. (2001-05-01). "Directed evolution of proteins by exon shuffling". Nature Biotechnology. 19 (5): 423–428Zero-shot learning (1,355 words) [view diff] case mismatch in snippet view article find links to article
Yisong; Arnold, Frances H. (2020-12-04). "Machine Learning-Assisted Directed Evolution Navigates a Combinatorial Epistatic Fitness Landscape with MinimalPseudonocardia autotrophica (322 words) [view diff] exact match in snippet view article find links to article
Tamura, Tomohiro (July 2009). "Purification, characterization, and directed evolution study of a vitamin D3 hydroxylase from Pseudonocardia autotrophica"Robustness (evolution) (4,629 words) [view diff] exact match in snippet view article
Gaillon L, Kast P, van Gunsteren WF, Marlière P, Hilvert D (2013). "Directed evolution of a model primordial enzyme provides insights into the developmentMicrobial genetics (5,154 words) [view diff] exact match in snippet view article find links to article
method of production is the ability to direct optimization by means of directed evolution. The efficiency and specificity of production will increase over timeAscorbate peroxidase (1,255 words) [view diff] exact match in snippet view article find links to article
KJ, Deerinck TJ, Ellisman MH, Mootha VK, Ting AY (January 2015). "Directed evolution of APEX2 for electron microscopy and proximity labeling". Nature MethodsMicrobiome (12,352 words) [view diff] exact match in snippet view article find links to article
PMID 26109480. Bloom, J. D.; Arnold, F. H. (2009). "In the light of directed evolution: Pathways of adaptive protein evolution". Proceedings of the NationalCircular permutation in proteins (3,519 words) [view diff] exact match in snippet view article find links to article
96.20.11241. PMC 18018. PMID 10500161. Turner NJ (August 2009). "Directed evolution drives the next generation of biocatalysts". Nature Chemical BiologyCas9 (5,610 words) [view diff] exact match in snippet view article find links to article
JK, Jeong E, Lee J, Jung M, Shin E, Kim YH, et al. (August 2018). "Directed evolution of CRISPR-Cas9 to increase its specificity". Nature CommunicationsAlkalihalobacillus alcalophilus (367 words) [view diff] exact match in snippet view article find links to article
of cold adaptation of Bacillus alcalophilus alkaline protease by directed evolution". Journal of Molecular Catalysis B: Enzymatic. 106: 117–123. doi:10Deoxyribozyme (4,795 words) [view diff] exact match in snippet view article find links to article
1073/pnas.0305943101. PMC 314139. PMID 14691255. Joyce GF (2004). "Directed evolution of nucleic acid enzymes". Annual Review of Biochemistry. 73 (1): 791–836List of biophysicists (2,490 words) [view diff] exact match in snippet view article find links to article
reactions of photosynthesis, genetic code, imaging spectroscopy and directed evolution Bruno Zimm — co-developer of the Zimm-Bragg model of helix formationEvidence of common descent (27,140 words) [view diff] exact match in snippet view article find links to article
such as proteins." Evolutionary molecular engineering, also called directed evolution or in vitro molecular evolution involves the iterated cycle of mutationExon shuffling (2,249 words) [view diff] exact match in snippet view article find links to article
PMID 14634634. S2CID 33999892. Kolkman JA, Stemmer WP (May 2001). "Directed evolution of proteins by exon shuffling". Nature Biotechnology. 19 (5): 423–428HKA test (819 words) [view diff] case mismatch in snippet view article find links to article
Example of Directed Evolution - SelectionEnadenotucirev (372 words) [view diff] case mismatch in snippet view article find links to article
ongoing clinical study. Oncolytic adenovirus Oncolytic adenovirus#Directed Evolution "Enadenotucirev". PsiOxus Therapeutics. Retrieved 2019-07-04. MachielsFerdinand Bohlmann (398 words) [view diff] case mismatch in snippet view article find links to article
California Institute of Technology United States Manfred T. Reetz 2004 Directed Evolution of Enantioselective Enzymes Max-Planck-Institut für KohlenforschungCell sorting (4,511 words) [view diff] exact match in snippet view article find links to article
"Ultrahigh-throughput screening in drop-based microfluidics for directed evolution". Proceedings of the National Academy of Sciences of the United StatesWolfgang Schad (724 words) [view diff] case mismatch in snippet view article find links to article
Vegetation in the Bergisch-Märkische Hügelland Wirz, Johannes (2014). "Directed Evolution: Commentary on Wolfgang Schad's Archäopteryx lithographica – einePhilipp Holliger (1,171 words) [view diff] exact match in snippet view article find links to article
PMID 9032075. Ghadessy, F. J.; Ong, J. L.; Holliger, P. (2001-03-27). "Directed evolution of polymerase function by compartmentalized self-replication". ProceedingsValery Taliev (1,218 words) [view diff] exact match in snippet view article find links to article
already existing cycles of individual development. Taliev explained directed evolution by the physical and chemical reasons and suggested that in the courseProject Veritas (21,105 words) [view diff] exact match in snippet view article find links to article
the video, stating that it had not done any "gain of function or directed evolution research" during its development of its COVID-19 vaccine. MultipleKinetic exclusion assay (2,005 words) [view diff] exact match in snippet view article find links to article
R. Anthony; Burton, Dennis R.; Plückthun, Andreas (2006-10-13). "Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM andOff-target genome editing (6,822 words) [view diff] exact match in snippet view article find links to article
increasingly robust and reliable RNA-guided nuclease editing tools. Directed evolution can also be used to reduce nuclease activity on particular targetMicrosomal epoxide hydrolase (2,780 words) [view diff] exact match in snippet view article find links to article
J, Archelas A, Bottalla AL, Naworyta A, Mowbray SL (June 2009). "Directed evolution of an enantioselective epoxide hydrolase: uncovering the source ofList of Bengalis (16,010 words) [view diff] exact match in snippet view article find links to article
Research Center Ananda Mohan Chakrabarty, most notable for his work in directed evolution and his role in developing a genetically engineered organism usingRNA hydrolysis (740 words) [view diff] case mismatch in snippet view article find links to article
PMID 7935797. S2CID 4314759. Beaudry, Amber; Joyce, Gerald (1992). "Directed Evolution of an RNA Enzyme". Science. 257 (5070): 635–641. Bibcode:1992Sci.BioTork (518 words) [view diff] exact match in snippet view article find links to article
Crecy, E; Jaronski, S; Lyons, B; Lyons, TJ; Keyhani, NO (2009). "Directed evolution of a filamentous fungus for thermotolerance". BMC Biotechnol. 9: 74List of biologists (20,745 words) [view diff] exact match in snippet view article find links to article
American biochemist and biochemical engineer, pioneer of the use of directed evolution to engineer enzymes. Ruth Arnon (born 1933), Israeli biochemist, whoAndrimid (785 words) [view diff] exact match in snippet view article find links to article
PMID 18652473. Fischbach MA, Lai JR, Roche ED, Walsh CT, Liu DR (July 2007). "Directed evolution can rapidly improve the activity of chimeric assembly-line enzymes"2018 in science (22,287 words) [view diff] exact match in snippet view article find links to article
laser physics" Nobel Prize in Chemistry – Frances H. Arnold, "for the directed evolution of enzymes", George P. Smith and Gregory P. Winter, "for the phageSteven A. Benner (3,871 words) [view diff] exact match in snippet view article find links to article
Benner, Steven A. (31 October 2014). "DNA polymerases engineered by directed evolution to incorporate non-standard nucleotides". Frontiers in MicrobiologyMorpheein (6,781 words) [view diff] exact match in snippet view article find links to article
"Simultaneous optimization of enzyme activity and quaternary structure by directed evolution". Protein Science. 14 (8): 2103–14. doi:10.1110/ps.051431605. PMC 2279322Optogenetic methods to record cellular activity (2,470 words) [view diff] case mismatch in snippet view article find links to article
Altermatt, Michael; Liang, Ruqiang; Matsui, Aya; et al. (December 2020). "Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning"FMN-binding fluorescent protein (1,563 words) [view diff] exact match in snippet view article find links to article
PMID 19060199. Mukherjee A, Weyant KB, Walker J, Schroeder CM (2012). "Directed evolution of bright mutants of an oxygen-independent flavin-binding fluorescentImmTAC (652 words) [view diff] exact match in snippet view article find links to article
Baston E, Dunn S, Liddy N, Jacob J, Jakobsen BK, Boulter JM (2005). "Directed evolution of human T-cell receptors with picomolar affinities by phage display"List of biochemists (10,432 words) [view diff] exact match in snippet view article find links to article
biochemist and biochemical engineer at Caltech, pioneer of the use of directed evolution to engineer enzymes. Nobel Prize for Chemistry (2018). Member NatlGene regulatory circuit (1,311 words) [view diff] exact match in snippet view article find links to article
S2CID 49222385. Yokobayashi, Y.; Weiss, R.; Arnold, F. H. (2002-12-24). "Directed evolution of a genetic circuit". Proceedings of the National Academy of SciencesJason Micklefield (1,611 words) [view diff] exact match in snippet view article find links to article
in biocatalysis. His lab employed structure-guided mutagenesis and directed evolution to improve activity, expand the substrate scope and switch the regioselectivitiesSabine Flitsch (1,243 words) [view diff] exact match in snippet view article find links to article
Flitsch’s research group has engineered tailored biocatalysts via directed evolution, and to address the biological challenge of 'sequencing' carbohydratesNiranjan Parajuli (1,893 words) [view diff] exact match in snippet view article find links to article
Parajuli, N., and Williams, G.J. (2011). A high-throughput screen for directed evolution of aminocoumarin amide synthetases. Analytical Biochemistry 419, 61–66Jürgen Brosius (2,480 words) [view diff] exact match in snippet view article find links to article
Genomics. 2003;3(1-4):1-17 Brosius J. From Eden to a hell of uniformity? Directed evolution in humans.Bioessays. 2003 Aug;25(8):815-21 Patent U.S. # 5,670,318Process chemistry (4,405 words) [view diff] exact match in snippet view article find links to article
transaminase enzyme from the bacteria Arthrobacter through 11 rounds of directed evolution. The engineered transaminase contained 27 individual point mutationsFluorescent glucose biosensor (7,448 words) [view diff] exact match in snippet view article find links to article
a single dye (Ianbd) attached to E149C as a starting point for a directed evolution screen, in which a mutant library is created and selected for "winners"History of eugenics (15,292 words) [view diff] case mismatch in snippet view article find links to article
edu. 6 June 2018. Retrieved 2018-10-01. Maxwell J. Mehlman, Will Directed Evolution Destroy Humanity, and If So, What Can We Do About It?, 3 St. LouisList of National Inventors Hall of Fame inductees (6,184 words) [view diff] case mismatch in snippet view article find links to article
invent.org. April 6, 2024. "NIHF Inductee Frances Arnold Pioneered Directed Evolution". www.invent.org. April 6, 2024. "Inductee Chieko Asakawa and theMurine respirovirus (31,229 words) [view diff] exact match in snippet view article find links to article
Kochneva GV, Netesov SV, Chumakov PM, Matveeva OV (July 2019). "Directed evolution as a tool for the selection of oncolytic RNA viruses with desiredImine reductase (866 words) [view diff] exact match in snippet view article find links to article
(2019-09-16). "Chiral synthesis of LSD1 inhibitor GSK2879552 enabled by directed evolution of an imine reductase". Nature Catalysis. 2 (10): 909–915. doi:10A. C. Matin (3,684 words) [view diff] exact match in snippet view article find links to article
enzyme for reductive cancer chemotherapy, YieF, and its improvement by directed evolution". Molecular Cancer Therapeutics. 5 (1): 97–103. doi:10.1158/1535-7163List of California Institute of Technology people (14,247 words) [view diff] exact match in snippet view article find links to article
Innovation recipient; Nobel laureate in chemistry (2018) "for the directed evolution of enzymes" Jay Bailey, former faculty John D. Baldeschwieler, NationalCsaba Pal (1,956 words) [view diff] exact match in snippet view article find links to article
2013.57. PMC 3817406. PMID 24169403. Bokor, Dóra (11 June 2018). "Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance"Recursive self-improvement (1,180 words) [view diff] exact match in snippet view article find links to article
might develop for itself. This forms the basis for a kind of self-directed evolution, where the agent can perform a kind of artificial selection, changingReward hacking (1,503 words) [view diff] exact match in snippet view article find links to article
'agenda' distinct from the programmer's" and that "the first rule of directed evolution is 'you get what you select for'". In 2013, programmer Tom MurphySelective organ targeting (2,174 words) [view diff] case mismatch in snippet view article find links to article
"Nanoparticles That Deliver RNA to Bone Marrow Identified by in Vivo Directed Evolution". Journal of the American Chemical Society. 140 (49): 17095–17105Shimshon Belkin (2,487 words) [view diff] exact match in snippet view article find links to article
6-trinitrotoluene by an Escherichia coli bioreporter: performance enhancement by directed evolution". Applied Microbiology and Biotechnology. 99 (17): 7177–7188. doi:10List of American Nobel laureates (186 words) [view diff] exact match in snippet view article find links to article
sensor" 2018 Frances Arnold Edgewood, Pennsylvania, U.S. "for the directed evolution of enzymes" 2017 Joachim Frank Siegen, Germany "for the discoveryBias in the introduction of variation (14,475 words) [view diff] exact match in snippet view article find links to article
"Making the case for orthogenesis: The popularization of definitely directed evolution (1890–1926)". Studies in History and Philosophy of Science Part C: