Find link

language: af: Afrikaans als: Alemannisch [Alemannic] am: አማርኛ [Amharic] an: aragonés [Aragonese] ar: العربية [Arabic] arz: مصرى [Egyptian Arabic] as: অসমীয়া [Assamese] ast: asturianu [Asturian] az: azərbaycanca [Azerbaijani] azb: تۆرکجه [Southern Azerbaijani] ba: башҡортса [Bashkir] bar: Boarisch [Bavarian] bat-smg: žemaitėška [Samogitian] be: беларуская [Belarusian] be-tarask: беларуская (тарашкевіца) [Belarusian (Taraškievica)] bg: български [Bulgarian] bn: বাংলা [Bengali] bpy: বিষ্ণুপ্রিয়া মণিপুরী [Bishnupriya Manipuri] br: brezhoneg [Breton] bs: bosanski [Bosnian] bug: ᨅᨔ ᨕᨘᨁᨗ [Buginese] ca: català [Catalan] ce: нохчийн [Chechen] ceb: Cebuano ckb: کوردیی ناوەندی [Kurdish (Sorani)] cs: čeština [Czech] cv: Чӑвашла [Chuvash] cy: Cymraeg [Welsh] da: dansk [Danish] de: Deutsch [German] el: Ελληνικά [Greek] en: English eo: Esperanto es: español [Spanish] et: eesti [Estonian] eu: euskara [Basque] fa: فارسی [Persian] fi: suomi [Finnish] fo: føroyskt [Faroese] fr: français [French] fy: Frysk [West Frisian] ga: Gaeilge [Irish] gd: Gàidhlig [Scottish Gaelic] gl: galego [Galician] gu: ગુજરાતી [Gujarati] he: עברית [Hebrew] hi: हिन्दी [Hindi] hr: hrvatski [Croatian] hsb: hornjoserbsce [Upper Sorbian] ht: Kreyòl ayisyen [Haitian] hu: magyar [Hungarian] hy: Հայերեն [Armenian] ia: interlingua [Interlingua] id: Bahasa Indonesia [Indonesian] io: Ido is: íslenska [Icelandic] it: italiano [Italian] ja: 日本語 [Japanese] jv: Basa Jawa [Javanese] ka: ქართული [Georgian] kk: қазақша [Kazakh] kn: ಕನ್ನಡ [Kannada] ko: 한국어 [Korean] ku: Kurdî [Kurdish (Kurmanji)] ky: Кыргызча [Kirghiz] la: Latina [Latin] lb: Lëtzebuergesch [Luxembourgish] li: Limburgs [Limburgish] lmo: lumbaart [Lombard] lt: lietuvių [Lithuanian] lv: latviešu [Latvian] map-bms: Basa Banyumasan [Banyumasan] mg: Malagasy min: Baso Minangkabau [Minangkabau] mk: македонски [Macedonian] ml: മലയാളം [Malayalam] mn: монгол [Mongolian] mr: मराठी [Marathi] mrj: кырык мары [Hill Mari] ms: Bahasa Melayu [Malay] my: မြန်မာဘာသာ [Burmese] mzn: مازِرونی [Mazandarani] nah: Nāhuatl [Nahuatl] nap: Napulitano [Neapolitan] nds: Plattdüütsch [Low Saxon] ne: नेपाली [Nepali] new: नेपाल भाषा [Newar] nl: Nederlands [Dutch] nn: norsk nynorsk [Norwegian (Nynorsk)] no: norsk bokmål [Norwegian (Bokmål)] oc: occitan [Occitan] or: ଓଡ଼ିଆ [Oriya] os: Ирон [Ossetian] pa: ਪੰਜਾਬੀ [Eastern Punjabi] pl: polski [Polish] pms: Piemontèis [Piedmontese] pnb: پنجابی [Western Punjabi] pt: português [Portuguese] qu: Runa Simi [Quechua] ro: română [Romanian] ru: русский [Russian] sa: संस्कृतम् [Sanskrit] sah: саха тыла [Sakha] scn: sicilianu [Sicilian] sco: Scots sh: srpskohrvatski / српскохрватски [Serbo-Croatian] si: සිංහල [Sinhalese] simple: Simple English sk: slovenčina [Slovak] sl: slovenščina [Slovenian] sq: shqip [Albanian] sr: српски / srpski [Serbian] su: Basa Sunda [Sundanese] sv: svenska [Swedish] sw: Kiswahili [Swahili] ta: தமிழ் [Tamil] te: తెలుగు [Telugu] tg: тоҷикӣ [Tajik] th: ไทย [Thai] tl: Tagalog tr: Türkçe [Turkish] tt: татарча/tatarça [Tatar] uk: українська [Ukrainian] ur: اردو [Urdu] uz: oʻzbekcha/ўзбекча [Uzbek] vec: vèneto [Venetian] vi: Tiếng Việt [Vietnamese] vo: Volapük wa: walon [Walloon] war: Winaray [Waray] yi: ייִדיש [Yiddish] yo: Yorùbá [Yoruba] zh: 中文 [Chinese] zh-min-nan: Bân-lâm-gú [Min Nan] zh-yue: 粵語 [Cantonese]

jump to random article

searching for Lipid 326 found (7073 total)

alternate case: lipid

Cell membrane (6,906 words) [view diff] exact match in snippet view article find links to article

space). The cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them

causing the enzyme to traffic to cholesterol dependent lipid domains sometimes called "lipid rafts". The substrate of phospholipase D is phosphatidylcholine

Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group

is a small artificial vesicle, spherical in shape, having at least one lipid bilayer. Due to their hydrophobicity and/or hydrophilicity, biocompatibility

Acids and Protein Synthesis, Enzymology and Biological Oxidation, Lipids and Lipid Metabolism and Mucoproteins and Mucopolysaccharides (ceased in 1965)

successful use of lipid rescue in this way. In the UK, efforts have been made to publicize lipid rescue more widely. In 2010, lipid rescue had been officially

glycolipoprotein lipid microdomains termed lipid rafts. Their existence in cellular membranes remains controversial. Indeed, Kervin and Overduin imply that lipid rafts

within or outside a cell, consisting of liquid or cytoplasm enclosed by a lipid bilayer. Vesicles form naturally during the processes of secretion (exocytosis)

their own lipid bilayers (also called membrane-bounded organelles) or are spatially distinct functional units without a surrounding lipid bilayer (non-membrane

membrane is found in gram-negative bacteria. Gram-negative bacteria form two lipid bilayers in their cell envelopes - an inner membrane (IM) that encapsulates

A lipid profile or lipid panel is a panel of blood tests used to find abnormalities in blood lipid ( such as cholesterol and triglycerides) concentrations

structures with respect to the lipid bilayer. Positions of the proteins are calculated using an implicit solvation model of the lipid bilayer. The results of

of the heart). It appears to be relatively safe in pregnancy. There is a lipid formulation that has a lower risk of side effects. It is in the polyene

thymocytes). This specialised group of glycoproteins present self and non-self lipid-based antigens to specific αβ T-cells. CD1 molecules are structurally related

cells. The mRNA is delivered by a co-formulation of the RNA encapsulated in lipid nanoparticles that protect the RNA strands and help their absorption into

number of areas of research in chemistry and biochemistry, notably that of lipid polymorphism. Organic compounds containing hydrophilic groups at both ends

and coronary heart disease via the mechanisms described by the lipid hypothesis. As lipid-lowering medications, statins are effective in lowering LDL cholesterol

beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human

beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human

These disorders may be described as fatty oxidation disorders or as a lipid storage disorders, and are any one of several inborn errors of metabolism

co-activator of adipose triglyceride lipase (ATGL/PNPLA2) that associates with lipid droplets in association with perilipin proteins. Phosphorylation of certain

amines) generally act on the surface of target cells via second messengers. Lipid soluble hormones, (such as steroids) generally pass through the plasma membranes

Pneumocystis Parasitic noninfectious Chemical/Mendelson's syndrome Aspiration/Lipid By vector/route Community-acquired Healthcare-associated Hospital-acquired

These processes include lipoprotein metabolism, cytokine expression, and lipid composition in cells. Unlike the lipases that hydrolyze Triglycerides, endothelial

most important lipid-soluble antioxidant, and that it protects membranes from oxidation by reacting with lipid radicals produced in the lipid peroxidation

increases, driving the conversion of DAG to PA. As both lipids are thought to function as bioactive lipid signaling molecules with distinct cellular targets

vitamin activity, nicotinamide does not have the same pharmacological, lipid-modifying effects or side effects as niacin, i.e., when niacin takes on

the actions of the latter (see below). The nuclear membrane contains a lipid bilayer that encompasses the contents of the nucleus. The endoplasmic reticulum

ENPP2 gene. Autotaxin is a secreted enzyme important for generating the lipid signaling molecule lysophosphatidic acid (LPA). Autotaxin has lysophospholipase

of the outer membrane pinch off, forming spherical structures made of a lipid bilayer enclosing periplasmic materials. Vesicles from a number of bacterial

of glycans, such as Lewis Y and Lewis X, attached to proteins instead of lipids. Once bound, the entire toxin complex is endocytosed by the cell and the

across. Peripheral membrane proteins are temporarily attached either to the lipid bilayer or to integral proteins by a combination of hydrophobic, electrostatic

leaflet of this membrane contains a complex lipopolysaccharide (LPS) whose lipid A component can trigger a toxic reaction when the bacteria are lysed by

Tetrafluoride, Chloroform and Ethrane in Dogs: Correlation with the Hydrate and Lipid Theories of Anesthetic Action". Anesthesiology: The Journal of the American

(not including subtypes), and each are classified from both the altered lipid profile and by the genetic abnormality. For example, high LDL (often due

Proteins that cross the membrane are surrounded by annular lipids, which are defined as lipids that are in direct contact with a membrane protein. Such

perilipins on the surface of lipid droplets within adipose cells. This triggers them to "spread out" and allow for HSL to enter the lipid droplet. Activation of

in seasonally arid environments have adapted an extra-epidermal layer of lipid and mucus as an evolutionary convergent response to accommodate the periodic

Flippases are transmembrane lipid transporter proteins located in the membrane. They are responsible for aiding the movement of phospholipid molecules

nuclear envelope, also known as the nuclear membrane, is made up of two lipid bilayer membranes that in eukaryotic cells surround the nucleus, which encloses

the lipid bilayer" meaning that any in plane tension in the lipid bilayer is felt homogenously in the absence of cytoskeleton interactions. The lipid molecules

belong to a new class of antibiotics, and harms bacteria by binding to lipid II and lipid III, important precursor molecules for forming the cell wall. Teixobactin

GPR55 and GPR119, GPR18 has been found to be a receptor for endogenous lipid neurotransmitters, several of which also bind to cannabinoid receptors.

and alkylacetyl-GPC:acetylhydrolase. This enzyme participates in ether lipid metabolism. As of late 2007, 7 structures have been solved for this class

of lipid and hydrocarbon polymers infused with wax, and is synthesized exclusively by the epidermal cells. The plant cuticle is a layer of lipid polymers

in the presentation of lipid antigens to T cells. CD1d is the only member of the group 2 CD1 molecules. CD1d-presented lipid antigens activate a special

triacylglycerides (in addition to phospholipids, esters of cholesterol, and lipid-soluble vitamins). In particular, they can hydrolyze esters of the essential

with hydrophobic and hydrophilic regions, conjugated bile salts sit at the lipid/water interface and, above the right concentration, form micelles. The added

chondrolysis. As for bupivacaine, Celepid, a commonly available intravenous lipid emulsion, can be effective in treating severe cardiotoxicity secondary to

alpha-helices or a transmembrane beta barrel. Because the interior of the lipid bilayer is hydrophobic, the amino acid residues in TMDs are often hydrophobic

membrane biology, fusion is the process by which two initially distinct lipid bilayers merge their hydrophobic cores, resulting in one interconnected

Complex of apical lipid globules are also involved in graviperception. These lipids are clustered in cellular structures, complex of lipid globules, about

associated with CHILD syndrome which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal

that in humans is encoded by the KCNK2 gene. This gene encodes K2P2.1, a lipid-gated ion channel belonging to the two-pore-domain background potassium

(bHLH-Zip) transcription factor family. SREBP-1a regulates genes related to lipid and cholesterol production and its activity is regulated by sterol levels

"Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects". Atherosclerosis. 191 (1): 63–72. doi:10.1016/j

Neutral lipid storage disease (also known as Chanarin–Dorfman syndrome) is a congenital autosomal recessive disorder characterized by accumulation of

encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins

(GIRKs) are a family of lipid-gated inward-rectifier potassium ion channels which are activated (opened) by the signaling lipid PIP2 and a signal transduction

individual will have an excessive number of VLDL and triglycerides on a lipid profile. This genetic disorder usually follows an autosomal dominant inheritance

rate-limiting reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation

dehydrogenase serves as a major link between carbohydrate metabolism and lipid metabolism. It is also a major contributor of electrons to the electron

prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. For the prevention of cardiovascular disease, statins are a first-line

with the saliva, catalyzes the first reaction in the digestion of dietary lipid, with diglycerides being the primary reaction product. However, due to the

Lipaemia retinalis is a white appearance of the retina, and can occur by lipid deposition in lipoprotein lipase deficiency. Retinal Detachment. The neural

host cell. Numerous human pathogenic viruses in circulation are encased in lipid bilayers, and they infect their target cells by causing the viral envelope

protein-coupled receptor family of integral membrane proteins that are important for lipid signaling. In humans, there are eleven LPL receptors, each encoded by a

functional cell membranes. According to this biological model, there is a lipid bilayer (two molecules thick layer consisting primarily of amphipathic phospholipids)

either low or absent lipoprotein lipase enzyme activity.[citation needed] Lipid measurements · Milky, lipemic plasma revealing severe hyperchylomicronemia;[citation

Gangliosidosis contains different types of lipid storage disorders caused by the accumulation of lipids known as gangliosides. There are two distinct genetic

protists and fungi. They lack lipid envelopes and package their segmented genome within multi-layered capsids. Lack of a lipid envelope has allowed three-dimensional

Lipaemia retinalis is a white appearance of the retina, and can occur by lipid deposition in lipoprotein lipase deficiency. Retinal Detachment. The neural

by the LPAR4 gene. LPA4 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA). Lysophospholipid receptor

vision varies. Puppies affected often have nystagmus. It is also known as lipid retinopathy. Progressive vision loss in any dog in the absence of canine

an increased number of Lipid A acyl tails by adding myristate to Lipid A with 2-hydroxymyristate and forming hepta-acylated Lipid A by adding palmitate

consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans caused by members of this order include

transport which involves the transport of large amount of substance like lipid droplets and solid food particles across plasma membrane by utilising energy

surrounding a skeletal muscle fibre or a cardiomyocyte. It consists of a lipid bilayer and a thin outer coat of polysaccharide material (glycocalyx) that

dairy in the presence of oxygen. In food, oxygen is readily available for lipid oxidation reactions. Oxygen also helps maintain high respiration rates of

sides of the lipid bilayer. Types I, II, III and IV are single-pass molecules. Type I transmembrane proteins are anchored to the lipid membrane with

have a large, prominent nucleus, an eosinophilic cytoplasm, and numerous lipid-filled vesicles. The mammalian Leydig cell is a polyhedral epithelioid cell

proliferation, and glucose and lipid metabolism. This protein has been shown to be involved in differentiation, lipid accumulation, directional sensing

a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is

(palmitoylation) are targeted to the ordered lipids through a specific lipid-lipid interaction. The binding of palmitate to the lipid domain is cholesterol dependent

Laropiprant (INN) was a drug used in combination with niacin to reduce blood cholesterol (LDL and VLDL) that is no longer sold, due to increases in side-effects

Amlodipine/atorvastatin, sold under the brand name Caduet among others, is a fixed-dose combination medication for the treatment of high cholesterol and

Pelizaeus–Merzbacher disease is an X-linked neurological disorder that damages oligodendrocytes in the central nervous system. It is caused by mutations

typical invaginations. The inner membrane of mitochondria is similar in lipid composition to the membrane of bacteria. This phenomenon can be explained

towards de novo fatty acid synthesis to supply lipids for membrane production and protein lipidation for fast cell proliferation. For example, PI3K-AKT

Abbott) is a combination drug consisting of an extended release form of the lipid-lowering drug niacin and the statin drug simvastatin. It is used for the

with peroxisomes. Its primary role is in fatty acid elongation or complex lipid synthesis rather than in degradation. This gene has a mouse ortholog. Solute

4-Oxo-2-nonenal is a lipid peroxidation product that can structurally alter proteins and induce α-synuclein oligomers. Näsström, Thomas; Fagerqvist, Therese;

combination used for the treatment of dyslipidemia. It was a combination of the lipid-modifying drug/vitamin niacin in extended release form and the statin drug

Cholib, is a fixed-dose combination medication used to treat abnormal blood lipid levels when used in combination with a low-fat diet and exercise. It contains

Fatty acid binding protein 7, brain (FABP7; also brain lipid binding protein, BLBP), is a human gene. The protein encoded by this gene is a brain fatty

Davidson KW, Epling JW, García FA, et al. (August 2016). "Screening for Lipid Disorders in Children and Adolescents: US Preventive Services Task Force

a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is

colipase for optimal enzymatic activity. Acidic lipases make up 30% of lipid hydrolysis occurring during digestion in the human adult, with gastric lipase

reactions, can serve as substrates for the synthesis of various kinds of lipids, including phospholipids, triglycerides, and can also be used as mediators

a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is

reactions, can serve as substrates for the synthesis of various kinds of lipids, including phospholipids, triglycerides, and can also be used as mediators

the absence or presence of an outer lipid membrane. All gram-positive bacteria are bounded by a single-unit lipid membrane, and, in general, they contain

colipase for optimal enzymatic activity. Acidic lipases make up 30% of lipid hydrolysis occurring during digestion in the human adult, with gastric lipase

Short-chain acyl-coenzyme A dehydrogenase deficiency (SCADD) is an autosomal recessive fatty acid oxidation disorder which affects enzymes required to

"Optical Anisotropy of Supported Lipid Structures Probed by Waveguide Spectroscopy and Its Application to Study of Supported Lipid Bilayer Formation Kinetics"

Fungicides are pesticides used to kill parasitic fungi or their spores. Fungi can cause serious damage in agriculture, resulting in critical losses of

(marketed as Bezalip and various other brand names) is a fibrate drug used as a lipid-lowering agent to treat hyperlipidaemia. It helps to lower LDL cholesterol

of an oil-rich nut, the source of edible shea butter, which is the major lipid source for many African ethnic groups and is also used in traditional and

the lysosomes. The primary function of lysosomal lipase is to hydrolyze lipids such as triglycerides and cholesterol. These fats are transported and degraded

lipoproteins (LDL). The opaqueness of the eye is caused by the deposit of lipids onto the cornea. Definitive diagnosis requires LCAT gene analysis for mutation

pore formation are the lipid-lined and protein-lined fusion pore theories. One possible model for fusion pore formation is the lipid-line pore theory. In

by the LPAR3 gene. LPA3 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA). This gene encodes a member

Canavan disease, or Canavan–Van Bogaert–Bertrand disease, is a rare and fatal autosomal recessive degenerative disease that causes progressive damage to

PMID 26945816. S2CID 37749661. synd/453 at Who Named It? Farber S (1952). "A lipid metabolic disorder: disseminated lipogranulomatosis; a syndrome with similarity

synthesis have an important implication in metabolic control of glucose, lipid, and energy homeostasis under normal and diabetic conditions. CYP7A1-rs3808607

by the LPAR5 gene. LPA5 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA). Lysophospholipid receptor

hypercholesterolemia (HoFH) to reduce LDL-C. Ezetimibe/rosuvastatin combines two lipid-lowering therapies with distinct actions to achieve greater lowering of

most commonly described in the scientific literature as a coat protein for lipid droplets. TIP47 belongs to the peripilin protein family and shares significant

of the lipid peroxidation product spectrum whether Fe2+/O2 or Fe3+/O2 is used as oxidant". Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

2-arachidonoylglycerol, 2-AG) on the other hand, are non-charged lipids that readily cross lipid membranes. However, since the endocannabinoids are water immiscible

of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. Additionally, they play an important role

geranylgeranyltransferase, posttranslationally modify proteins by adding an isoprenoid lipid called a prenyl group to the carboxyl terminus of the target protein. This

Tetherin, also known as bone marrow stromal antigen 2, is a lipid raft associated protein that in humans is encoded by the BST2 gene. In addition, tetherin

name Juxtapid in the US and Lojuxta in the EU, is a medication used as a lipid-lowering agent for the treatment of familial hypercholesterolemia, developed

by the LPAR2 gene. LPA2 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA). This gene encodes a member

coenzyme substructure, which classifies it as a fatty ester lipid molecule. Being a lipid makes the molecule hydrophobic, which makes it insoluble in

carboxylase, glucose transporter type 4 (Glut 4) and so on. Through this process, lipid droplets accumulate in the adipocyte. However, preadipocytes cell lines

a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). This protein participates

Cerebrotendinous xanthomatosis, also called cerebral cholesterosis, is an autosomal recessive form of xanthomatosis. It falls within a group of genetic

Familial dysbetalipoproteinemia or type III hyperlipoproteinemia is a condition characterized by increased total cholesterol and triglyceride levels, and

a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). This protein participates

carboxylase, glucose transporter type 4 (Glut 4) and so on. Through this process, lipid droplets accumulate in the adipocyte. However, preadipocytes cell lines

Cerebrotendinous xanthomatosis, also called cerebral cholesterosis, is an autosomal recessive form of xanthomatosis. It falls within a group of genetic

by the LPAR1 gene. LPA1 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA). The integral membrane protein

is sometimes found with the GRAM domain. Myotubularin is a dual-specific lipid phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and

structural change and form a beta-barrel, that pierces through the host cell’s lipid bilayer. Leukocidins get their names by killing ("-cide") leukocytes. Leukocidins

PPAR-alpha as master regulator of lipid metabolism via regulation of numerous genes involved in various aspects of lipid metabolism. These maps, constructed

class of lipid storage disorders or degenerative storage disorders caused by deficiency of an enzyme that is required for the catabolism of lipids that contain

as cPLA2-α C2 domain bind to zwitterionic lipids (e.g. PC). This diversity and selectivity in Ca2+ and lipid binding suggest that C2 domains are evolved

product. Both lipid peroxidation and oxidative stress can cause membrane damage. Lipid peroxidation and oxidative stress take place as lipid peroxidation

constituents of the cytoskeleton. This domain can bind phosphatidylinositol lipids within biological membranes (such as phosphatidylinositol (3,4,5)-trisphosphate

present a danger to persons with a nut allergy, because oils are primarily lipids, and allergic reactions are due to surface proteins on the nut. The seeds

macroscopically appears as a bright red mucosa with yellow mottling (due to lipid), hence the term strawberry gallbladder. It is not tied to cholelithiasis

Schonfeld G (May 2003). "Familial hypobetalipoproteinemia: a review". J. Lipid Res. 44 (5): 878–83. doi:10.1194/jlr.R300002-JLR200. PMID 12639976. Young

carrier') is a chemical species that reversibly binds ions. Many ionophores are lipid-soluble entities that transport ions across the cell membrane. Ionophores

platform consisting of a polymer-bound chemotherapeutic drug combined with a lipid-bound anti-angiogenesis drug. Nanocells are currently being developed in

Lipomatosis is believed to be an autosomal dominant condition in which multiple lipomas are present on the body. Many discrete, encapsulated lipomas form

storage and glucose metabolism. The genes activated by PPARG stimulate lipid uptake and adipogenesis by fat cells. PPARG knockout mice are devoid of

broad functions across inflammation, cell development, viral responses, and lipid metabolism. As an immunosuppressive cytokine, IL-19 promotes the Th2 (regulatory)

(FABPs) represent a family of proteins that play a pivotal role in cellular lipid metabolism. These proteins act as intracellular carriers, facilitating the

Sitagliptin/simvastatin, sold under the brand name Juvisync, is a fixed-dose combination anti-diabetic medication used to treat type 2 diabetes and hypercholesterolemia

bacterial toxins, dephosphorylating phosphorylated nucleotides, regulating lipid absorption in the intestine, and regulating the microbiome in the intestine

correlation between genotype and phenotype, neither the amount of stored lipids, nor the residual enzyme activity correlates well with disease symptoms

Ciprofibrate is a fibrate that was developed as a lipid-lowering agent. It was patented in 1972 and approved for medical use in 1985. Fischer J, Ganellin

primary catalyzed reaction of PLC occurs on an insoluble substrate at a lipid-water interface. The residues in the active site are conserved in all PLC

adequate amounts of the LAL enzyme. Blood tests may show anaemia and their lipid profiles are generally similar to people with more common familial hypercholesterolemia

diagnosis. Metabolic risk factors such as hyperglycaemia, oxidative stress and lipid peroxidation are common processes thought to be contributors to the development

and the ability of the drug to bind tissue and plasma proteins and its lipid solubility. pH partition plays a major role as well. The drug is easily

BR (May 2000). "A broad role for the zinc finger protein ZNF202 in human lipid metabolism". The Journal of Biological Chemistry. 275 (21): 15685–90. doi:10

caused by sources such as reactive oxygen species, free radicals, peroxides, lipid peroxides, and heavy metals. It is a tripeptide with a gamma peptide linkage

chemistry Vesicle (biology and chemistry), a supramolecular assembly of lipid molecules, like a cell membrane Synaptic vesicle In human embryology Vesicle

and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can also transport big organic cations like dopamine

on to the fatty (lipid) tissues of the brain where it can exert its effect. The potency of an anesthetic is associated with its lipid solubility, which

Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug. In the United States, it was approved in May 2013, by

ATP-sensitive inward rectifier potassium channel 12 is a lipid-gated ion channel that in humans is encoded by the KCNJ12 gene. This gene encodes an inwardly

Bempedoic acid/ezetimibe, sold under the brand name Nexlizet among others, is a fixed-dose combination medication used for the treatment of high cholesterol

(July 2002). "The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind". J. Biol. Chem. 277 (29): 25847–50. doi:10

and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can also transport big organic cations like dopamine

transport by lipid peroxidation. Conjugated double bonds in nystatin's structure steal electron density from ergosterol in fungal cell membranes. Lipid peroxidation

– June 7, 2002) was an American medical researcher, principally of the lipid and cholesterol metabolism, and director of National Institutes of Health

of 1,3-propanediol and two molecules of clofibric acid which is the true lipid-lowering agent. Verma N (2016). "Introduction to Hyperlipidemia and its

toxicity, possibly by preserving lysosome integrity against iron-induced lipid peroxidation. However, it potentiates the toxic effects of cadmium and nickel

acid (EPA) by the enzyme arachidonate 5-lipoxygenase. Leukotrienes use lipid signaling to convey information to either the cell producing them (autocrine

1993, the structure of the gramicidin head-to-head dimer in micelles and lipid bilayers was determined by solution and solid-state NMR. Gramicidins A,

Expeller pressing (also called oil pressing) is a mechanical method for extracting oil from raw materials. The raw materials are squeezed under high pressure

is an oral medication of the fibrate class used to treat abnormal blood lipid levels. It is less commonly used compared than statins because it treats

Suarez EC (1 May 1999). "Relations of trait depression and anxiety to low lipid and lipoprotein concentrations in healthy young adult women". Psychosom

transesterification methods. The residual biomass harbors valuable components such as lipids, proteins, and soluble polysaccharides. These components can be leveraged

and cellular cholesterol efflux in subjects with familial low HDL". J. Lipid Res. 48 (6): 1409–16. doi:10.1194/jlr.P600012-JLR200. PMID 17372331. v t

absorption.[medical citation needed] It also elicits a satiety signal from lipid-filled cells lining the intestine.[medical citation needed] It is supplied

squalene epoxidase is localized to both the endoplasmic reticulum and lipid droplets. Only the ER localized protein is active. Squalene epoxidase also

Abetalipoproteinemia typically consists of stool sampling, a blood smear, and a fasting lipid panel, though these tests are not confirmatory. As the disease is rare,

thylakoid lipid bilayer shares characteristic features with prokaryotic membranes and the inner chloroplast membrane. For example, acidic lipids can be found

encoded by the MTM1 gene. This gene is a member of a gene family that encodes lipid phosphatases. Myotubularin is required for muscle cell differentiation and

Tangier disease or hypoalphalipoproteinemia is an extremely rare inherited disorder characterized by a severe reduction in the amount of high density lipoprotein

undergo associated with pseudoapoptosis include blebbing, plasma membrane lipid asymmetry, cytoskeleton alterations, changes in mitochondrial function,

Berardinelli-Seip congenital lipodystrophy 2 (seipin), seipin lipid droplet biogenesis associated, BSCL2 lipid droplet biogenesis associated, seipin, HMN5C External

fibers that transmit pain. GI-tract pain is likely caused by accumulation of lipids in the small vasculature of the GI tract, which obstructs blood flow and

The Kir2.1 inward-rectifier potassium channel is a lipid-gated ion channel encoded by the KCNJ2 gene. A defect in this gene is associated with Andersen-Tawil

functions an individual layer can serve. For example, an intercellular lipid lamella is formed when lamellar disks fuse to form a lamellar sheet. It

Ezetimibe/simvastatin is a drug combination used for the treatment of dyslipidemia. It is a combination of ezetimibe (known as Zetia in the United States)

"Apical sodium bile acid transporter and ileal lipid binding protein in gallstone carriers". J. Lipid Res. 47 (1): 42–50. doi:10.1194/jlr.M500215-JLR200

obtained either by dietary consumption or by metabolism of choline-containing lipids is converted to PC, accounts for approximately 70% of PC biosynthesis in

Animal evidence indicates intralipid, a commonly available intravenous lipid emulsion, can be effective in treating severe cardiotoxicity secondary to

The core class (including vancomycin) binds to acyl-D-alanyl-D-alanine in lipid II, preventing the addition of new units to the peptidoglycan. Of this core

infection.[citation needed] C. parvum is incapable of de novo lipid synthesis, making its lipid trafficking machinery an important potential therapeutic target

Alkylresorcinols (ARs), also known as resorcinolic lipids, are amphiphilic phenolic lipids characterised by a non-polar odd-numbered alkyl side chain

lipid content in the blood leads to excessive cytoplasm loading of lipids within histiocytes. The subsequent incomplete degradation of these lipids leads

Schindler disease, also known as Kanzaki disease and alpha-N-acetylgalactosaminidase deficiency, is a rare disease found in humans. This lysosomal storage

Sandhoff disease is a lysosomal genetic, lipid storage disorder caused by the inherited deficiency to create functional beta-hexosaminidases A and B.

non-estrogenic means. A 2021 review found that lignans have a positive effect on lipid profiles of patients with dyslipidemia related diseases. As of 2022 there

which reduce LDL-cholesterol (LDL-C) and have only limited effects on other lipid parameters. Clinical trials have shown that the combination of statins and

receives fatty chyle from the intestines and thus acts as a conduit for the lipid products of digestion. It is the most common drainage trunk of most of the

Perilipin, also known as lipid droplet-associated protein, perilipin 1, or PLIN, is a protein that, in humans, is encoded by the PLIN gene. The perilipins

recessive inheritance pattern. Like many other genetic disorders that affect lipid metabolism, there are several forms of MLD, which are late infantile, juvenile

mediators from storage granules and concurrent synthesis of inflammatory lipid mediators from arachidonic acid; some of these mediators include histamine

oil, also known as Microbial oil consists of the intracellular storage lipids, triacyglycerols. It is similar to vegetable oil, another biologically produced

glycerophospholipids, where it is used for activation and transfer of diacylglycerol and lipid head groups, and glycosylation of proteins. CTP acts as an inhibitor of

protein that is required to oxidize fatty acids. They are an inborn error of lipid metabolism, and when it affects the muscles also a metabolic myopathy. The

cytosol of a eukaryotic cell, usually surrounded by a single or double lipid layer membrane. These compartments are often, but not always, defined as

fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain

efflux positive regulation of pancreatic juice secretion lipid homeostasis negative regulation of lipid transport transcription initiation from RNA polymerase

concentration of cholesterol, which is considered, by those who accept the standard lipid hypothesis, an important determinant of atherosclerosis. This enzyme is

follicle-stimulating hormone, luteinizing hormone and insulin. These molecules are not lipid-soluble and therefore cannot diffuse through cell membranes. Consequently

a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is

cytoplasm and have the potential for membrane association either through their lipid-binding PX domain (a phospholipid-binding motif) or through protein–protein

organic anions across the cell membrane. Therefore, OATPs are present in the lipid bilayer of the cell membrane, acting as the cell's gatekeepers. OATPs belong

of cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis of higher organisms. Three types of PPARs have

organic anions across the cell membrane. Therefore, OATPs are present in the lipid bilayer of the cell membrane, acting as the cell's gatekeepers. OATPs belong

Trimethylamine N-oxide (TMAO) is an organic compound with the formula (CH3)3NO. It is in the class of amine oxides. Although the anhydrous compound is

(NOX4), ROS accumulation and oxidative DNA damage. Besides being a potent lipid mediator in asthma and inflammation, LTC4 was reported to be involved in

Myristoylation is a lipidation modification where a myristoyl group, derived from myristic acid, is covalently attached by an amide bond to the alpha-amino

Lipid II is a precursor molecule in the synthesis of the cell wall of bacteria. It is a peptidoglycan, which is amphipathic and named for its bactoprenol

all alterations elicited by the toxin, like mitochondrial dysfunction and lipid peroxidation, by activation of the CB1 receptor. Roberts, Toby John (2004)

Infantile neuronal ceroid lipofuscinoses (INCL) or Santavuori disease or Hagberg-Santavuori disease or Santavuori-Haltia disease or Infantile Finnish type

a lipid called 10(Z)-hexadecenoic acid found in Mycobacterium vaccae, and discovered that inside stimulated immune cells (macrophages), the lipid binds

on the surface of target cells via second messengers; the latter, being lipid-soluble, move through the plasma membranes of target cells (both cytoplasmic

involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and functions as a

quaternary ammonium compounds, involving binding to the negatively charged lipid membranes of pathogens. Hexamidine and its shorter congener, propamidine

intravenous fluids and norepinephrine may be used. The use of intravenous lipid emulsion may also be tried. In the early 2000s, TCAs were one of the most

peroxide generating and scavenging activities. They perform key roles in lipid metabolism and the reduction of reactive oxygen species. Peroxisomes are

involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain

of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells". J. Lipid Res. 39 (6): 1152–61. doi:10.1016/S0022-2275(20)32539-6

Polygonum aviculare, Rhododendron aureum and Taxillus kaempferi. It suppresses lipid accumulation through repression of C/EBPα-activated GLUT4-mediated glucose

macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Several alternative splice variants have

of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development

nitrite has been found to give taste and color to the meat and inhibit lipid oxidation that leads to rancidity, with varying degrees of effectiveness

formed on linoleic acid that is esterified to a sphingosine in a complex lipid termed esterified omega-hydroxylacyl-sphingosin (EOS). The full structural

Fenofibrate/pravastatin, sold under the brand name Pravafenix, is a combination medication for the treatment of hypercholesterolemia (high blood cholesterol

to –40 mV. All animal cells are surrounded by a membrane composed of a lipid bilayer with proteins embedded in it. The membrane serves as both an insulator

Sulfatidosis is a form of lysosomal storage disease resulting in a proliferation of sulfatide. It is caused by a genetic insufficiency of sulfatase enzymes

potassium-specific transporter and facilitates the movement of potassium ions through lipid membranes "down" the electrochemical potential gradient. The stability constant

nifedipine with positive inotropic activity, and as an aromatic it is highly lipid soluble. Bay K8644 targets L-type voltage-gated calcium channels. It is

brand name Lopid among others, is a medication used to treat abnormal blood lipid levels. It is generally less preferred than statins. Use is recommended

reducing lipid oxidation of yakgwa. The use of ginger powder instead of the traditional ginger juice used in the recipe helps support the lipid oxidative

to the corresponding diols. A different region of this protein also has lipid-phosphate phosphatase activity. Mutations in the EPHX2 gene have been associated

respectively). In addition, some molecules such as steroid hormones are lipid-soluble and thus cross the plasma membrane to reach cytoplasmic or nuclear

the viral cell entry of Herpes simplex virus (HSV). Herpesviruses have a lipid bilayer, called the envelope, which contains twelve surface glycoproteins

Jansky–Bielschowsky disease is an extremely rare autosomal recessive genetic disorder that is part of the neuronal ceroid lipofuscinosis (NCL) family of

the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism". Journal of Lipid Research. 51 (6): 1513–23. doi:10.1194/jlr.M004812. PMC 3035515

Sulfatidosis is a form of lysosomal storage disease resulting in a proliferation of sulfatide. It is caused by a genetic insufficiency of sulfatase enzymes

A. Price Foundation is known for its controversial position against the lipid hypothesis, maintaining a positive stance towards the consumption of saturated

the viral cell entry of Herpes simplex virus (HSV). Herpesviruses have a lipid bilayer, called the envelope, which contains twelve surface glycoproteins

important in cell signaling. Due to their size, cytokines cannot cross the lipid bilayer of cells to enter the cytoplasm and therefore typically exert their

site when catalysis is not coordinated correctly, resulting in potential lipid peroxidation as well as protein and DNA oxidation. CYP2E1 is particularly

to the corresponding diols. A different region of this protein also has lipid-phosphate phosphatase activity. Mutations in the EPHX2 gene have been associated

between omega-3 fatty acids and cardiac disease?". Prostaglandins & Other Lipid Mediators. 96 (1–4): 99–108. doi:10.1016/j.prostaglandins.2011.09.001. PMID 21945326

covalently bound to lipid A plays also and indispensable role in TLR4 activation through CD14/TLR4/MD-2. However, in addition to the lipid A domain, the polysaccharide

NBIA disorders have also been associated with several genes in synapse and lipid metabolism related pathways. NBIA is not one disease but an entire group

Sialic acid is a negatively charged sugar associated with the protein and lipid portions of lipoproteins.[citation needed] To infect a host cell, the influenza

a macrolide glycopeptide antibiotic. Dirithromycin (Dynabac) is a more lipid-soluble prodrug derivative of 9S-erythromycyclamine prepared by condensation

process lipid glycosylation regulation of actin filament polymerization regulation of microtubule polymerization regulation of membrane lipid distribution

alkenones remains under debate although it is likely that they are storage lipids. Alkenones were first described in ocean sediments recovered from Walvis

treatment of atherosclerosis. It is said to have beneficial effects on serum lipid profiles while producing minimal feminization, though some estrogenic side

distribution, metabolism, analysis, and health-promoting uses". Progress in Lipid Research. 70: 35–61. doi:10.1016/j.plipres.2018.04.001. ISSN 1873-2194.

The delivery of mRNA is achieved by a coformulation of the molecule into lipid nanoparticles, which protect the RNA strands and help their absorption into

sphingomyelin and cholesterol metabolism in growing 293 cells". Journal of Lipid Research. 43 (9): 1380–9. doi:10.1194/jlr.M200130-JLR200. PMID 12235169

that is widely distributed in tissues. In rough terms, drugs with a high lipid solubility (non-polar drugs), low rates of ionization, or low plasma protein

vitamin activity, nicotinamide does not have the same pharmacological, lipid-modifying effects or side effects as niacin, i.e., when niacin takes on

therefore be used for lipid metabolic disorders in a clinical setting. Chrysophanol has also been shown to exhibit the same properties lipid lowering in rats

Apolipoprotein B deficiency is an autosomal dominant disorder resulting from a missense mutation which reduces the affinity of apoB-100 for the low-density

solved (Protein Databank Accession Number 2A79​), and then refined in a lipid membrane-like environment (PDB: 2r9r​). Voltage-gated K+ channels are selective

Acyl-coenzyme A thioesterase 11 also known as StAR-related lipid transfer protein 14 (STARD14) is an enzyme that in humans is encoded by the ACOT11 gene

(Nicotinamide), to which it is slowly hydrolysed. Niceritrol has been used as a lipid regulating drug in hyperlipidaemias and as a vasodilator in the treatment

organisms include excitation of neurons in epilepsy and lipid peroxidation. In peroxidation, a lipid radical reacts with oxygen to form a peroxyl radical

pollutant. In cell membrane cytochemistry, perylene is used as a fluorescent lipid probe. It is the parent compound of a class of rylene dyes. Like other polycyclic

Kir6.2 is a major subunit of the ATP-sensitive K+ channel, a lipid-gated inward-rectifier potassium ion channel. The gene encoding the channel is called

participate in phosphatidylinositol 4,5-bisphosphate (PIP2) metabolism and lipid signaling pathways in a calcium-dependent manner. At present, the family

Nedergaard, Thrane and colleagues also showed that the paravascular transport of lipids through the glymphatic pathway activated glial calcium signalling and that

basic groove that forms the binding pocket for the Ins(1,4,5)P3 ligand. The lipid ligand is coordinated by residues from surrounding alpha-helices and all

Kv7.2 (KvLQT2) is a voltage- and lipid-gated potassium channel protein coded for by the gene KCNQ2. It is associated with benign familial neonatal epilepsy

shown to have cytotoxic properties as well as antioxidant properties on lipid peroxidation. Tebufenozide, sold under the Bayer trademark MIMIC, has ecdysteroid

Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a lipid-lowering agent. It reduces triglyceride levels and increases HDL cholesterol

bacteria. CSAs have a high binding affinity for such membranes (including Lipid A) and are able to rapidly disrupt the target membranes leading to rapid

approaches help facilitate siRNA delivery to target cells: lipid nanoparticles and conjugates. Lipid nanoparticles (LNPs) are based on liposome-like structures

(NAPE). NAPE-PLD facilitates crosstalk between bile acid signals and lipid amide signals. LCA was also shown to have anti-aging effects in a yeast

formation, protein folding, insertion of membrane proteins into the nonpolar lipid environment and protein-small molecule associations. Hence the hydrophobic

ulceration and neovascularization, fibrous cap thickness, and presence of a lipid-rich necrotic core (LNRC). Carotid ultrasound is the preferred initial diagnostic

triglycerides are hydrolyzed and free fatty acids are released. This reaction of lipid with water may require a catalyst (such as a lipase, or acidic or alkaline

producing long-lasting cytostasis in cells. Lipopolysaccharide (LPS) and lipid A-associated protein – studies have demonstrated that LPS and LAP are potent

gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer. Sialidase-3 has been shown to interact with Grb2. GRCh38: Ensembl

sodium salt of the enolate (m.p. 245 °C). Malondialdehyde results from lipid peroxidation of polyunsaturated fatty acids. It is a prominent product in

approaches help facilitate siRNA delivery to target cells: lipid nanoparticles and conjugates. Lipid nanoparticles (LNPs) are based on liposome-like structures

StAR-related lipid transfer protein 15 (STARD15) is an enzyme that in humans is encoded by the ACOT12 gene. The protein contains a StAR-related lipid transfer

formation, protein folding, insertion of membrane proteins into the nonpolar lipid environment and protein-small molecule associations. Hence the hydrophobic

ulceration and neovascularization, fibrous cap thickness, and presence of a lipid-rich necrotic core (LNRC). Carotid ultrasound is the preferred initial diagnostic

great importance in the field of biotechnology. Colonies held together by a lipid biofilm matrix can be found in temperate or tropical oligotrophic lakes

originated. It is suggested to have been a "cellular organism that had a lipid bilayer and used DNA, RNA, and protein". The LUCA has also been defined

lipoprotein complex formed by type II alveolar cells. The proteins and lipids that comprise surfactant have both a hydrophilic region and a hydrophobic

46 mmol/L (4.5 mg/dL). Levels may appear falsely elevated with high blood lipid levels, high blood protein levels, or high blood bilirubin levels. Treatment

metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer

near-shore submerged cages. Juveniles thrive on a wide range of protein and lipid, but there are optimal levels where they get the most benefit. After an

production of an extremely small version of the protein that cannot transport lipids properly. A loss of functional ABCA12 protein causes numerous problems with

phospholipase. The virions consist of an envelope, a core, and an internal lipid membrane associated with the inner particle. The virus capsid is enveloped

therefore considered to be the prototype of synthetic anti-cancer lipids. "The antitumor ether lipid Edelfosine (ET-18-O-CH3) induces apoptosis in H-ras transformed

chylomicrons are subject to delipidation by lipoprotein lipase. Eventually, enough lipid has been lost and additional apolipoproteins gained, that the resulting

metabolic processes. Loss of hepatic Nfe2l1 has been shown to result in lipid accumulation, hepatocellular damage, cysteine accumulation, and altered

fewer catabolic substrates and have distinct morphological characteristics, lipid compositions, and RNA sequences. Their cell walls are composed of pseudomurein

sphingolipids. When hexosaminidase A is no longer functioning properly, the lipids accumulate in the brain and interfere with normal biological processes.

of GM1 lipid rafts in response to astrocyte cholesterol. Cholesterol delivered by apolipoprotein E (ApoE) drives APP to associate with GM1 lipid rafts

Polygodial’s primary antifungal action is as a nonionic surfactant, disrupting the lipid-protein interface of integral proteins nonspecifically, denaturing their

(MTB). They contain iron-rich magnetic particles that are enclosed within a lipid bilayer membrane. Each magnetosome can often contain 15 to 20 magnetite

in the lysosomes, that breaks down lipids. When beta-hexosaminidase is no longer functioning properly, the lipids accumulate in the nervous tissue of

scavenging of free radical species and carbonyl species formed in sugar and lipid degradation and chelation of metal ions that catalyze Amadori reactions

protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different

fully understood. Some are lipid-linked to form lipoteichoic acids. Because lipoteichoic acids are covalently linked to lipids within the cytoplasmic membrane

sterol absorption and excretion. Mutations in either genes result in a lipid disorder, sitosterolemia. The molecular mechanisms regulating the absorption

never-marketed antiestrogen ethamoxytriphetol (MER-25): 7  and the withdrawn lipid-lowering agent triparanol, as both contain the 1,1,2-triphenylethanol moiety

activity metal ion binding protein binding ATPase-coupled intramembrane lipid transporter activity hydrolase activity ATP binding magnesium ion binding

beta-hexosaminidase A, a critical enzyme in the nervous system that breaks down a lipid called GM2 ganglioside. If mutations in both alleles at this locus disrupt

transport of proteins, structural proteins, cell-maintaining proteins, lipids, and other substances through the cell. Long nerve fibers (axons) are affected

Inward-rectifier potassium channels (Kir, IRK) are a specific lipid-gated subset of potassium channels. To date, seven subfamilies have been identified

The National Lipid Association (NLA) is an American non-profit multidisciplinary medical society that aims to enhance the practice of lipid management in

lipid composition within the cephalic melon tissue of the pilot whale (Globicephala melaena)". Biochimica et Biophysica Acta (BBA) - Lipids and Lipid

epidermin are members of a family of lantibiotics that bind to lipid II, a cell wall precursor lipid component of target bacteria and disrupt cell wall production

sphingosine kinase. The resulting sphingosine-1-phosphate is a potent signaling lipid. Sphingosine is also a substrate for the synthesis of various other molecules