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searching for G1/S transition 217 found (233 total)

alternate case: g1/S transition

Deubiquitinating enzyme (4,318 words) [view diff] no match in snippet view article find links to article

cell through the cell cycle. Activation of CDK2 is critical for the G1-S transition. For CDK2 to be activated, cyclin A must bind to the cyclin-dependent
Cell division cycle 7-related protein kinase (1,746 words) [view diff] exact match in snippet view article find links to article
the different phases of cell cycle. The concentration of Dbf4 at the G1/S transition of the cell cycle is higher than the concentration at the M/G1 transition
Cyclin E1 (1,720 words) [view diff] exact match in snippet view article find links to article
regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded
Cyclin-dependent kinase 6 (4,042 words) [view diff] exact match in snippet view article find links to article
protein kinase complex, important for the G1 phase progression and G1/S transition of the cell cycle and the complex is composed also by an activating
E2F (1,910 words) [view diff] exact match in snippet view article find links to article
DNA-binding motif. E2F family members play a major role during the G1/S transition in mammalian and plant cell cycle (see KEGG cell cycle pathway). DNA
Cytochalasin D (137 words) [view diff] no match in snippet view article find links to article
the p53-dependent pathways causing arrest of the cell cycle at the G1-S transition. It is believed to bind to F-actin polymer and prevent polymerization
E2F1 (1,875 words) [view diff] exact match in snippet view article find links to article
apoptotic process negative regulation of transcription involved in G1/S transition of mitotic cell cycle positive regulation of fibroblast proliferation
LATS2 (746 words) [view diff] exact match in snippet view article find links to article
Xia H, et al. (2003). "Lats2, a putative tumor suppressor, inhibits G1/S transition". Oncogene. 22 (28): 4398–405. doi:10.1038/sj.onc.1206603. PMID 12853976
Cyclin-dependent kinase 2 (4,286 words) [view diff] no match in snippet view article find links to article
sites of this gene have been reported. The role of this protein in G1-S transition has been recently questioned as cells lacking Cdk2 are reported to
Cyclin-dependent kinase 4 (2,367 words) [view diff] exact match in snippet view article find links to article
(RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor
P21 (3,978 words) [view diff] exact match in snippet view article find links to article
the cell cycle and in response to DNA damage. Specifically, over the G1/S transition it has been demonstrated that the E3 ubiquitin ligase complex SCFSkp2
Transcription factor DP (117 words) [view diff] no match in snippet view article find links to article
which binds to the E2F-DP heterodimer and negatively regulates the G1-S transition. E2F TFDP1 TFDP2 Rubin SM, Gall AL, Zheng N, Pavletich NP (December
PLK3 (1,212 words) [view diff] exact match in snippet view article find links to article
reactive oxygen species mitotic cell cycle checkpoint signaling mitotic G1/S transition checkpoint signaling positive regulation of proteasomal ubiquitin-dependent
Wee1-like protein kinase (1,028 words) [view diff] exact match in snippet view article find links to article
phosphorylation phosphorylation mitotic cell cycle G1/S transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle mitotic cell cycle
Cyclin D1 (5,694 words) [view diff] exact match in snippet view article find links to article
subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein
ORC1 (1,433 words) [view diff] exact match in snippet view article find links to article
regulation of transcription involved in G1/S transition of mitotic cell cycle DNA replication initiation G1/S transition of mitotic cell cycle mitotic cell
APC/C activator protein CDH1 (1,551 words) [view diff] no match in snippet view article find links to article
Cdh1 (cdc20 homolog 1) is one of the substrate adaptor proteins of the anaphase-promoting complex (APC) in the budding yeast Saccharomyces cerevisiae.
CDC45-related protein (1,112 words) [view diff] exact match in snippet view article find links to article
break-induced replication regulation of transcription involved in G1/S transition of mitotic cell cycle pre-replicative complex assembly involved in
ID2 (1,251 words) [view diff] exact match in snippet view article find links to article
cytoplasm protein-containing complex Biological process regulation of G1/S transition of mitotic cell cycle rhythmic process negative regulation of DNA-binding
CDKN2C (1,270 words) [view diff] exact match in snippet view article find links to article
protein serine/threonine kinase activity G1/S transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle Sources:Amigo /
UHRF1 (1,302 words) [view diff] exact match in snippet view article find links to article
during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition, and functions in the p53-dependent DNA damage checkpoint. Multiple
Cyclin D2 (1,332 words) [view diff] exact match in snippet view article find links to article
subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the
PRIM1 (464 words) [view diff] exact match in snippet view article find links to article
replication, synthesis of RNA primer telomere maintenance via semi-conservative replication G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Cyclin D3 (1,604 words) [view diff] exact match in snippet view article find links to article
subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the
DNA replication factor CDT1 (1,439 words) [view diff] exact match in snippet view article find links to article
cell cycle DNA replication regulation of transcription involved in G1/S transition of mitotic cell cycle regulation of DNA-dependent DNA replication initiation
CDKN2D (1,227 words) [view diff] exact match in snippet view article find links to article
transition G1/S transition of mitotic cell cycle negative regulation of cyclin-dependent protein serine/threonine kinase activity negative regulation of G1/S transition
Ribosomal protein S6 (378 words) [view diff] exact match in snippet view article find links to article
biogenesis glucose homeostasis negative regulation of apoptotic process erythrocyte development G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
KIF14 (580 words) [view diff] exact match in snippet view article find links to article
division substrate adhesion-dependent cell spreading regulation of G1/S transition of mitotic cell cycle cell proliferation in forebrain regulation of
PRIM2 (654 words) [view diff] exact match in snippet view article find links to article
biosynthetic process telomere maintenance via semi-conservative replication G1/S transition of mitotic cell cycle DNA replication initiation Sources:Amigo / QuickGO
E2F7 (428 words) [view diff] exact match in snippet view article find links to article
cell differentiation negative regulation of transcription involved in G1/S transition of mitotic cell cycle placenta development DNA damage response, signal
DNA polymerase alpha catalytic subunit (1,768 words) [view diff] exact match in snippet view article find links to article
lagging strand elongation regulation of transcription involved in G1/S transition of mitotic cell cycle DNA replication leading strand elongation cell
Cell cycle (8,991 words) [view diff] exact match in snippet view article find links to article
checkpoint by not being ready yet, they will be discarded from dividing. G1/S transition is a rate-limiting step in the cell cycle and is also known as restriction
Mir-26 microRNA precursor family (3,054 words) [view diff] exact match in snippet view article find links to article
synergistically with their host genes, CTDSPL, CTDSP2 and CTDSP1, to block G1/S transition by activating the pRb protein in MHCC-97L, HepG2 and HuH7 liver cancer
POLE4 (264 words) [view diff] exact match in snippet view article find links to article
Biological process histone H3 acetylation DNA biosynthetic process G1/S transition of mitotic cell cycle DNA replication initiation telomere maintenance
DBF4 (969 words) [view diff] exact match in snippet view article find links to article
protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells". Molecular and Cellular Biology. 19 (7): 5083–95
CCL12 (236 words) [view diff] exact match in snippet view article find links to article
of vascular endothelial cell proliferation negative regulation of G1/S transition of mitotic cell cycle positive regulation of endothelial cell apoptotic
POLE3 (586 words) [view diff] exact match in snippet view article find links to article
process DNA replication histone H3 acetylation DNA biosynthetic process G1/S transition of mitotic cell cycle cellular response to DNA damage stimulus CENP-A
CDKN2A (3,317 words) [view diff] exact match in snippet view article find links to article
preventing transcription of E2F1 target genes which are crucial for the G1/S transition. During this process, a feedback loop exists between P16 and Rb, and
Trunk neural crest (271 words) [view diff] exact match in snippet view article find links to article
trunk neural crest delamination linking BMP/noggin signaling with G1/S transition". Development. 131 (21): 5327–39. doi:10.1242/dev.01424. PMID 15456730
POLE2 (523 words) [view diff] exact match in snippet view article find links to article
translesion synthesis DNA replication DNA-dependent DNA replication G1/S transition of mitotic cell cycle DNA replication initiation telomere maintenance
MIZF (763 words) [view diff] exact match in snippet view article find links to article
damage checkpoint signaling regulation of transcription involved in G1/S transition of mitotic cell cycle negative regulation of gene expression transcription
ID4 (3,046 words) [view diff] no match in snippet view article find links to article
ID4 is expressed in the central nervous system and is required for G1-S transition and to enhance proliferation in early cortical progenitors. It is complexly
ZNF259 (473 words) [view diff] exact match in snippet view article find links to article
regulation of myelination positive regulation of transcription involved in G1/S transition of mitotic cell cycle RNA splicing spinal cord development positive
CDC6 (1,361 words) [view diff] exact match in snippet view article find links to article
regulation of DNA replication regulation of transcription involved in G1/S transition of mitotic cell cycle cell division positive regulation of cytokinesis
Syncytin-1 (2,024 words) [view diff] exact match in snippet view article find links to article
syncytiotrophoblast layer. Syncytin-1 expression in cytotrophoblasts promotes G1/S transition and proliferation thereby ensuring continual replenishment of the cytotrophoblast
ADAMTS1 (1,009 words) [view diff] exact match in snippet view article find links to article
regulation of cell population proliferation positive regulation of G1/S transition of mitotic cell cycle positive regulation of vascular associated smooth
Tretinoin (2,940 words) [view diff] exact match in snippet view article find links to article
studies have shown that tretinoin plays a regulatory role in the G1/S transition of neuroblastoma cells by influencing the activities of key kinases
GSPT1 (1,153 words) [view diff] exact match in snippet view article find links to article
biosynthesis cytoplasmic translational termination protein methylation translational termination G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
DNA polymerase alpha subunit 2 (787 words) [view diff] exact match in snippet view article find links to article
process DNA replication initiation telomere maintenance via semi-conservative replication G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
SCF complex (2,021 words) [view diff] exact match in snippet view article find links to article
complexes. These findings indicated that proteolysis is important in the G1/S transition. Next, biochemical studies revealed that Cdc34 is an E2 enzyme that
ORC6 (881 words) [view diff] exact match in snippet view article find links to article
G1 phase DNA replication DNA replication initiation negative regulation of cell division G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
ORC5 (983 words) [view diff] exact match in snippet view article find links to article
nucleoplasm cytosol Biological process G1 phase DNA replication DNA replication initiation G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Cyclin D/Cdk4 (2,805 words) [view diff] exact match in snippet view article find links to article
D protein, whose concentration increases until it peaks around the G1/S transition. In the early to middle stages of G1 phase, Cyclin D binds to the constitutively
GJC2 (714 words) [view diff] exact match in snippet view article find links to article
proliferation positive regulation of calcium ion transmembrane transport negative regulation of G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Cyclin-dependent kinase 3 (771 words) [view diff] exact match in snippet view article find links to article
G2/M transition of mitotic cell cycle regulation of gene expression G1/S transition of mitotic cell cycle regulation of cell cycle Sources:Amigo / QuickGO
ZNF655 (585 words) [view diff] exact match in snippet view article find links to article
cytoplasm nucleolus nucleus Biological process negative regulation of G1/S transition of mitotic cell cycle regulation of transcription, DNA-templated transcription
ORC3 (974 words) [view diff] exact match in snippet view article find links to article
initiation pre-replicative complex assembly involved in nuclear cell cycle DNA replication G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Cyclin-dependent kinase (3,829 words) [view diff] exact match in snippet view article find links to article
S/G2 transition CDK2 cyclin E G1/S transition CDK3 cyclin C G0/G1 and G1/S transitions CDK4, CDK6 cyclin D G1/S transition. Phosphorylation of retinoblastoma
ORC4 (1,126 words) [view diff] exact match in snippet view article find links to article
nucleoplasm cytosol Biological process G1 phase DNA replication DNA replication initiation G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
MCM4 (1,256 words) [view diff] exact match in snippet view article find links to article
DNA replication initiation DNA unwinding involved in DNA replication G1/S transition of mitotic cell cycle double-strand break repair via break-induced
PLRG1 (693 words) [view diff] exact match in snippet view article find links to article
Biological process protein localization to nucleus positive regulation of G1/S transition of mitotic cell cycle mRNA processing RNA splicing mRNA splicing, via
MCM5 (1,223 words) [view diff] exact match in snippet view article find links to article
replication cell cycle DNA duplex unwinding DNA replication initiation G1/S transition of mitotic cell cycle double-strand break repair via break-induced
PIAS1 (1,351 words) [view diff] exact match in snippet view article find links to article
sumoylation protein-DNA complex assembly positive regulation of transcription, DNA-templated G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
BACH1 (1,169 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II regulation of transcription involved in G1/S transition of mitotic cell cycle transcription, DNA-templated regulation of transcription
PHF8 (971 words) [view diff] exact match in snippet view article find links to article
cell cycle positive regulation of transcription by RNA polymerase I G1/S transition of mitotic cell cycle chromatin organization Sources:Amigo / QuickGO
CDKN2B (1,386 words) [view diff] exact match in snippet view article find links to article
spleen development cellular response to nutrient negative regulation of G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle negative
SKP2 (4,001 words) [view diff] exact match in snippet view article find links to article
feedback loops with both p21 and p27, that control cell cycle entry and G1/S transition. Skp2 behaves as an oncogene in cell systems and is an established
P16 (4,236 words) [view diff] exact match in snippet view article find links to article
regulation of cell population proliferation G1/S transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle apoptotic process
CDKN3 (1,091 words) [view diff] exact match in snippet view article find links to article
proliferation dephosphorylation peptidyl-tyrosine dephosphorylation protein dephosphorylation G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
ORC2 (1,480 words) [view diff] exact match in snippet view article find links to article
replication negative regulation of transcription by RNA polymerase II DNA replication initiation G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Cyclin (1,760 words) [view diff] exact match in snippet view article find links to article
G1/S cyclins – essential for the control of the cell cycle at the G1/S transition, Cyclin A / CDK2 – active in S phase. Cyclin D / CDK4, Cyclin D / CDK6
Amidophosphoribosyltransferase (1,568 words) [view diff] exact match in snippet view article find links to article
homotetramerization lactation purine ribonucleoside monophosphate biosynthetic process G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
MCM3 (1,553 words) [view diff] exact match in snippet view article find links to article
process G1 phase DNA replication DNA replication initiation cell cycle G1/S transition of mitotic cell cycle double-strand break repair via break-induced
Estrogen-related receptor beta (800 words) [view diff] exact match in snippet view article find links to article
inner ear development positive regulation of transcription involved in G1/S transition of mitotic cell cycle positive regulation of transcription involved
MCM2 (1,600 words) [view diff] exact match in snippet view article find links to article
in DNA replication apoptotic process cell cycle cochlea development G1/S transition of mitotic cell cycle negative regulation of DNA helicase activity
GFI1 (1,256 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II regulation of transcription involved in G1/S transition of mitotic cell cycle transcription, DNA-templated negative regulation
ETS2 (1,420 words) [view diff] no match in snippet view article find links to article
virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cells". Oncogene.
FHL1 (1,423 words) [view diff] exact match in snippet view article find links to article
Biological process animal organ morphogenesis negative regulation of G1/S transition of mitotic cell cycle multicellular organism development cell differentiation
TCF3 (1,187 words) [view diff] exact match in snippet view article find links to article
positive regulation of transcription, DNA-templated regulation of G1/S transition of mitotic cell cycle B cell lineage commitment positive regulation
Cyclin A1 (1,435 words) [view diff] exact match in snippet view article find links to article
cell cycle male meiosis I regulation of transcription involved in G1/S transition of mitotic cell cycle spermatogenesis protein deubiquitination regulation
MCM7 (1,647 words) [view diff] exact match in snippet view article find links to article
proliferation DNA unwinding involved in DNA replication DNA replication G1/S transition of mitotic cell cycle double-strand break repair via break-induced
E2F4 (1,287 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II regulation of transcription involved in G1/S transition of mitotic cell cycle blood circulation cell projection organization
MCM6 (1,681 words) [view diff] exact match in snippet view article find links to article
DNA replication initiation DNA unwinding involved in DNA replication G1/S transition of mitotic cell cycle double-strand break repair via break-induced
POLE (gene) (1,103 words) [view diff] exact match in snippet view article
replication leading strand elongation DNA replication proofreading G1/S transition of mitotic cell cycle mitotic cell cycle DNA replication initiation
KCNA5 (1,460 words) [view diff] exact match in snippet view article find links to article
during bundle of His cell action potential positive regulation of G1/S transition of mitotic cell cycle potassium ion transport regulation of vasoconstriction
CDC25A (1,642 words) [view diff] exact match in snippet view article find links to article
deubiquitination positive regulation of cell cycle G2/M phase transition G1/S transition of mitotic cell cycle positive regulation of G2/M transition of mitotic
RPA4 (376 words) [view diff] exact match in snippet view article find links to article
DNA replication DNA repair cellular response to DNA damage stimulus G1/S transition of mitotic cell cycle telomere maintenance via recombination double-strand
LATS1 (1,129 words) [view diff] exact match in snippet view article find links to article
of ubiquitin-dependent protein catabolic process mitotic cell cycle G1/S transition of mitotic cell cycle peptidyl-serine phosphorylation intracellular
MYC (1,172 words) [view diff] exact match in snippet view article find links to article
complex disassembly ERK1 and ERK2 cascade cellular response to hypoxia G1/S transition of mitotic cell cycle cytokine-mediated signaling pathway positive
Eukaryotic translation initiation factor 4 gamma 1 (1,672 words) [view diff] exact match in snippet view article find links to article
miRNA regulation of cellular response to stress positive regulation of G1/S transition of mitotic cell cycle negative regulation of neuron death positive
PSME3 (1,149 words) [view diff] exact match in snippet view article find links to article
pathway MAPK cascade Fc-epsilon receptor signaling pathway regulation of G1/S transition of mitotic cell cycle NIK/NF-kappaB signaling cell cycle anaphase-promoting
KCNA5 (1,460 words) [view diff] exact match in snippet view article find links to article
during bundle of His cell action potential positive regulation of G1/S transition of mitotic cell cycle potassium ion transport regulation of vasoconstriction
Retinoblastoma-like protein 2 (1,534 words) [view diff] exact match in snippet view article find links to article
mitotic cell cycle cell differentiation regulation of cell division negative regulation of G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Thymidylate synthase (1,902 words) [view diff] exact match in snippet view article find links to article
response to glucocorticoid regulation of transcription involved in G1/S transition of mitotic cell cycle dTTP biosynthetic process tetrahydrofolate metabolic
SPDYA (345 words) [view diff] exact match in snippet view article find links to article
stimulus activation of protein kinase activity positive regulation of protein kinase activity G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
PSME2 (1,178 words) [view diff] exact match in snippet view article find links to article
pathway MAPK cascade Fc-epsilon receptor signaling pathway regulation of G1/S transition of mitotic cell cycle NIK/NF-kappaB signaling anaphase-promoting complex-dependent
CTDSP2 (426 words) [view diff] exact match in snippet view article find links to article
component nucleus nucleoplasm Biological process negative regulation of G1/S transition of mitotic cell cycle negative regulation of protein phosphorylation
RRM2 (1,042 words) [view diff] exact match in snippet view article find links to article
complex Biological process regulation of transcription involved in G1/S transition of mitotic cell cycle deoxyribonucleotide biosynthetic process DNA
CDC34 (1,341 words) [view diff] exact match in snippet view article find links to article
ubiquitin-dependent protein catabolic process protein ubiquitination G1/S transition of mitotic cell cycle ubiquitin-dependent protein catabolic process
RANBP3L (67 words) [view diff] exact match in snippet view article find links to article
differentiation mesenchymal cell differentiation involved in bone development G1/S transition of mitotic cell cycle protein export from nucleus Sources:Amigo / QuickGO
Replication protein A1 (1,549 words) [view diff] exact match in snippet view article find links to article
maintenance telomere maintenance via semi-conservative replication G1/S transition of mitotic cell cycle DNA unwinding involved in DNA replication telomere
PPP6C (504 words) [view diff] exact match in snippet view article find links to article
vesicle coating protein dephosphorylation immune system process innate immune response G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
CTDSP1 (434 words) [view diff] exact match in snippet view article find links to article
regulation of transcription by RNA polymerase II negative regulation of G1/S transition of mitotic cell cycle negative regulation of protein phosphorylation
KLF11 (1,397 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II regulation of transcription involved in G1/S transition of mitotic cell cycle transcription, DNA-templated negative regulation
PIM2 (gene) (1,990 words) [view diff] exact match in snippet view article
kinase/NF-kappaB signaling positive regulation of transcription, DNA-templated protein stabilization G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
ACVR1B (1,542 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II activin receptor signaling pathway G1/S transition of mitotic cell cycle transforming growth factor beta receptor signaling
PSME1 (1,255 words) [view diff] exact match in snippet view article find links to article
regulation of proteasomal protein catabolic process regulation of G1/S transition of mitotic cell cycle regulation of mRNA stability antigen processing
ACVR1 (1,052 words) [view diff] exact match in snippet view article find links to article
to mesenchymal transition involved in endocardial cushion formation G1/S transition of mitotic cell cycle pattern specification process Sources:Amigo /
INHBA (1,109 words) [view diff] exact match in snippet view article find links to article
follicle-stimulating hormone secretion regulation of signaling receptor activity G1/S transition of mitotic cell cycle response to wounding regulation of apoptotic
FGF10 (1,338 words) [view diff] exact match in snippet view article find links to article
receptor activity positive regulation of protein kinase B signaling positive regulation of G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Calcium/calmodulin-dependent protein kinase type II subunit alpha (1,466 words) [view diff] exact match in snippet view article find links to article
differentiation intracellular signal transduction protein phosphorylation G1/S transition of mitotic cell cycle dendritic spine development regulation of synaptic
LSM10 (617 words) [view diff] exact match in snippet view article find links to article
nucleoplasm nuclear body Biological process positive regulation of G1/S transition of mitotic cell cycle termination of RNA polymerase II transcription
CTDSPL (629 words) [view diff] exact match in snippet view article find links to article
extracellular exosome nucleus Biological process negative regulation of G1/S transition of mitotic cell cycle negative regulation of protein phosphorylation
USP37 (532 words) [view diff] exact match in snippet view article find links to article
deubiquitination proteolysis cell division regulation of DNA replication protein deubiquitination G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
SLFN11 (573 words) [view diff] exact match in snippet view article find links to article
of DNA damage chromosome Biological process negative regulation of G1/S transition of mitotic cell cycle defense response to virus immune system process
Retinoblastoma-like protein 1 (1,999 words) [view diff] exact match in snippet view article find links to article
mitotic cell cycle cell differentiation regulation of cell division negative regulation of G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
ANKRD17 (571 words) [view diff] exact match in snippet view article find links to article
regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of G1/S transition of mitotic cell cycle innate immune response viral process positive
Polycystin 2 (1,206 words) [view diff] exact match in snippet view article find links to article
import cellular response to osmotic stress negative regulation of G1/S transition of mitotic cell cycle heart looping metanephric S-shaped body morphogenesis
KMT2E (252 words) [view diff] exact match in snippet view article find links to article
regulation of transcription, DNA-templated positive regulation of G1/S transition of mitotic cell cycle positive regulation of histone H3-K4 trimethylation
MAX (gene) (2,347 words) [view diff] exact match in snippet view article
transcription by RNA polymerase II negative regulation of G0 to G1 transition G1/S transition of mitotic cell cycle protein-containing complex assembly positive
ECD (gene) (499 words) [view diff] exact match in snippet view article
nucleoplasm R2TP complex cytosol Biological process regulation of G1/S transition of mitotic cell cycle cell population proliferation regulation of transcription
Butyrophilin, subfamily 2, member A2 (388 words) [view diff] exact match in snippet view article find links to article
kinase B signaling negative regulation of ERK1 and ERK2 cascade negative regulation of G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
CYP1A1 (1,835 words) [view diff] exact match in snippet view article find links to article
arsenic-containing substance response to organic substance positive regulation of G1/S transition of mitotic cell cycle response to vitamin A response to lipopolysaccharide
TFDP2 (651 words) [view diff] exact match in snippet view article find links to article
apoptotic signaling pathway regulation of transcription involved in G1/S transition of mitotic cell cycle transcription by RNA polymerase II positive regulation
IFT88 (850 words) [view diff] no match in snippet view article find links to article
transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells". J. Cell Sci. 120 (Pt 4): 628–37. doi:10.1242/jcs
PPP3CA (562 words) [view diff] exact match in snippet view article find links to article
of connective tissue replacement positive regulation of endocytosis G1/S transition of mitotic cell cycle protein dephosphorylation calcineurin-NFAT signaling
SENP2 (691 words) [view diff] exact match in snippet view article find links to article
development negative regulation of signal transduction by p53 class mediator regulation of G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
UBE2L3 (2,124 words) [view diff] exact match in snippet view article find links to article
protein levels via the ubiquitin proteolytic pathway (UPP) during the G1/S transition and during the actual S phase. Through genome-wide association studies
Mitotic exit (3,400 words) [view diff] no match in snippet view article find links to article
budding yeast, was shown to be particularly important in irreversible G1-S transition by irreversibly activating S phase kinases. Sic1 level was shown to
CRLF3 (645 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II positive regulation of receptor signaling pathway via JAK-STAT G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
ADAM17 (2,387 words) [view diff] exact match in snippet view article find links to article
negative regulation of cold-induced thermogenesis positive regulation of G1/S transition of mitotic cell cycle positive regulation of tumor necrosis factor-mediated
ANKRD25 (527 words) [view diff] exact match in snippet view article find links to article
cytoplasm mitochondrion Biological process negative regulation of G1/S transition of mitotic cell cycle negative regulation of programmed cell death
FAM107A (708 words) [view diff] exact match in snippet view article find links to article
negative regulation of long-term synaptic potentiation negative regulation of G1/S transition of mitotic cell cycle cell cycle Sources:Amigo / QuickGO
PTPN6 (2,292 words) [view diff] exact match in snippet view article find links to article
immune response mediated by circulating immunoglobulin regulation of G1/S transition of mitotic cell cycle negative regulation of T cell proliferation regulation
Integrin beta 1 (2,600 words) [view diff] exact match in snippet view article find links to article
organization positive regulation of protein localization to plasma membrane G1/S transition of mitotic cell cycle phagocytosis cytokine-mediated signaling pathway
PRMT2 (793 words) [view diff] exact match in snippet view article find links to article
Biological process developmental cell growth negative regulation of G1/S transition of mitotic cell cycle positive regulation of transcription, DNA-templated
GPR132 (2,706 words) [view diff] exact match in snippet view article find links to article
regulation of G2/M transition of mitotic cell cycle G protein-coupled receptor signaling pathway G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
MCM10 (990 words) [view diff] exact match in snippet view article find links to article
response to DNA damage stimulus cell population proliferation DNA replication initiation G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
CCL2 (2,415 words) [view diff] exact match in snippet view article find links to article
of vascular endothelial cell proliferation negative regulation of G1/S transition of mitotic cell cycle positive regulation of endothelial cell apoptotic
Cyclin-dependent kinase 7 (2,347 words) [view diff] exact match in snippet view article find links to article
repair, preincision complex assembly DNA repair protein stabilization G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle transcription
CCL2 (2,415 words) [view diff] exact match in snippet view article find links to article
of vascular endothelial cell proliferation negative regulation of G1/S transition of mitotic cell cycle positive regulation of endothelial cell apoptotic
P70-S6 Kinase 1 (2,127 words) [view diff] exact match in snippet view article find links to article
response to dexamethasone stimulus cellular response to insulin stimulus G1/S transition of mitotic cell cycle peptidyl-serine phosphorylation TOR signaling
BRD7 (1,072 words) [view diff] exact match in snippet view article find links to article
regulation of transcription, DNA-templated negative regulation of G1/S transition of mitotic cell cycle cell cycle negative regulation of transcription
Replication protein A3 (920 words) [view diff] exact match in snippet view article find links to article
maintenance telomere maintenance via semi-conservative replication G1/S transition of mitotic cell cycle DNA mismatch repair nucleotide-excision repair
DIAPH1 (1,260 words) [view diff] exact match in snippet view article find links to article
in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition". The Journal of Biological Chemistry. 279 (25): 26323–30. doi:10.1074/jbc
MAPK/ERK pathway (3,102 words) [view diff] no match in snippet view article find links to article
has been linked to various activities involved in the regulation of G1S transition of the mammalian cell cycle, the underlying mechanism remains unclear
RCC1 (1,280 words) [view diff] exact match in snippet view article find links to article
mitotic nuclear division protein heterotetramerization regulation of molecular function G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
CUL4B (2,948 words) [view diff] exact match in snippet view article find links to article
monoubiquitination cellular response to DNA damage stimulus positive regulation of G1/S transition of mitotic cell cycle global genome nucleotide-excision repair cell
CUL1 (1,072 words) [view diff] exact match in snippet view article find links to article
cellular iron ion homeostasis post-translational protein modification G1/S transition of mitotic cell cycle interleukin-1-mediated signaling pathway SCF-dependent
PTEN (gene) (3,313 words) [view diff] exact match in snippet view article
signaling pathway response to organic substance negative regulation of G1/S transition of mitotic cell cycle regulation of B cell apoptotic process angiogenesis
RANBP3 (805 words) [view diff] exact match in snippet view article find links to article
GTPase activity positive regulation of mitotic centrosome separation G1/S transition of mitotic cell cycle protein export from nucleus Sources:Amigo / QuickGO
Philadelphia chromosome (3,538 words) [view diff] exact match in snippet view article find links to article
phosphorylate transcription factors which play a role in driving the G1/S transition of the cell cycle. The c-Abl gene in wild-type cells is implicated
Regulator of cell cycle RGCC (578 words) [view diff] exact match in snippet view article find links to article
regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Biochemical cascade (11,432 words) [view diff] no match in snippet view article find links to article
inactivates Rb. This leads to a short G1 phase of the cell cycle with rapid G1-S transition and little dependence on mitogenic signals or D cyclins for S phase
CUL4A (4,418 words) [view diff] exact match in snippet view article find links to article
regulation of cell population proliferation positive regulation of G1/S transition of mitotic cell cycle intrinsic apoptotic signaling pathway regulation
PLCB1 (1,248 words) [view diff] exact match in snippet view article find links to article
transcription, DNA-templated lipid catabolic process positive regulation of G1/S transition of mitotic cell cycle interleukin-1-mediated signaling pathway positive
FBXO5 (1,130 words) [view diff] exact match in snippet view article find links to article
of meiotic nuclear division regulation of transcription involved in G1/S transition of mitotic cell cycle cell division spindle assembly oocyte maturation
Cell division (4,250 words) [view diff] no match in snippet view article find links to article
through before entering the M phase. The most important being the G1-S transition checkpoint. If the cell does not pass this checkpoint, it results in
MNAT1 (1,407 words) [view diff] exact match in snippet view article find links to article
activity nucleotide-excision repair protein-containing complex assembly G1/S transition of mitotic cell cycle negative regulation of DNA helicase activity
CUL2 (1,418 words) [view diff] exact match in snippet view article find links to article
protein catabolic process post-translational protein modification G1/S transition of mitotic cell cycle protein ubiquitination SCF-dependent proteasomal
Geminin (1,608 words) [view diff] exact match in snippet view article find links to article
negative regulation of DNA-dependent DNA replication protein-containing complex assembly G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Extrachromosomal rDNA circle (1,080 words) [view diff] exact match in snippet view article find links to article
interfering with the expression of important cell cycle genes at the G1/S transition and thus delay cell cycle progression. The ERC accumulate in the mother
CACUL1 (483 words) [view diff] exact match in snippet view article find links to article
population proliferation positive regulation of protein kinase activity G1/S transition of mitotic cell cycle protein ubiquitination Sources:Amigo / QuickGO
NPAT (gene) (914 words) [view diff] exact match in snippet view article
transcription, DNA-templated regulation of transcription involved in G1/S transition of mitotic cell cycle transcription, DNA-templated negative regulation
CUL5 (1,305 words) [view diff] exact match in snippet view article find links to article
response to DNA damage stimulus post-translational protein modification G1/S transition of mitotic cell cycle SCF-dependent proteasomal ubiquitin-dependent
BRD4 (2,098 words) [view diff] exact match in snippet view article find links to article
regulation of DNA damage checkpoint regulation of transcription involved in G1/S transition of mitotic cell cycle transcription, DNA-templated cellular response
AKT1 (2,850 words) [view diff] exact match in snippet view article find links to article
oxidised low-density lipoprotein particle stimulus positive regulation of G1/S transition of mitotic cell cycle negative regulation of leukocyte cell-cell adhesion
SEPT7 (1,194 words) [view diff] exact match in snippet view article find links to article
regulation of apoptotic process cytoskeleton-dependent cytokinesis negative regulation of G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Neuronal cell cycle (2,128 words) [view diff] exact match in snippet view article find links to article
E2F1 which is necessary for DNA replication (Liu et al., 1998). The G1/S transition is regulated by cyclin E binding to Cdk2 which phosphorylates Rb as
TFDP1 (1,379 words) [view diff] exact match in snippet view article find links to article
transcription, DNA-templated regulation of transcription involved in G1/S transition of mitotic cell cycle transcription by RNA polymerase II negative regulation
Radixin (1,146 words) [view diff] exact match in snippet view article find links to article
cell migration regulation of GTPase activity positive regulation of G1/S transition of mitotic cell cycle negative regulation of homotypic cell-cell adhesion
NASP (gene) (978 words) [view diff] exact match in snippet view article
development blastocyst development histone exchange response to testosterone G1/S transition of mitotic cell cycle cell cycle CENP-A containing chromatin assembly
TAF10 (1,493 words) [view diff] exact match in snippet view article find links to article
organism growth regulation of DNA binding hepatocyte differentiation G1/S transition of mitotic cell cycle positive regulation of nucleic acid-templated
DDX3X (1,790 words) [view diff] exact match in snippet view article find links to article
DNA-templated cellular response to osmotic stress positive regulation of G1/S transition of mitotic cell cycle intrinsic apoptotic signaling pathway positive
CHEK1 (3,340 words) [view diff] exact match in snippet view article find links to article
cell cycle arrest can occur at multiple time points including the G1/S transition, S phase and G2/M transition. Furthermore, Chk1 can target Cdc25 indirectly
Replication protein A2 (1,479 words) [view diff] exact match in snippet view article find links to article
maintenance telomere maintenance via semi-conservative replication G1/S transition of mitotic cell cycle telomere maintenance via recombination DNA topological
RANBP1 (1,196 words) [view diff] exact match in snippet view article find links to article
organization positive regulation of mitotic centrosome separation RNA export from nucleus G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Cyclin H (1,468 words) [view diff] exact match in snippet view article find links to article
serine/threonine kinase activity regulation of transcription by RNA polymerase II G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle transcription
CDC73 (1,258 words) [view diff] exact match in snippet view article find links to article
DNA-templated stem cell population maintenance negative regulation of G1/S transition of mitotic cell cycle positive regulation of Wnt signaling pathway
MCM8 (911 words) [view diff] exact match in snippet view article find links to article
cellular response to DNA damage stimulus DNA replication initiation G1/S transition of mitotic cell cycle recombinational interstrand cross-link repair
RBBP8 (1,794 words) [view diff] exact match in snippet view article find links to article
transition negative regulation of nucleic acid-templated transcription G1/S transition of mitotic cell cycle regulation of signal transduction by p53 class
Annexin A1 (2,157 words) [view diff] exact match in snippet view article find links to article
secretion regulation of leukocyte migration positive regulation of G1/S transition of mitotic cell cycle cellular response to glucocorticoid stimulus
Clb 5,6 (Cdk1) (1,120 words) [view diff] exact match in snippet view article
(SBF) and MCB-binding factor (MBF), Clb5 and Clb6 can activate the G1/S transition in the absence of the G1 cyclins Cln1,2,3. These gene regulatory proteins
SMARCA4 (2,714 words) [view diff] exact match in snippet view article find links to article
positive regulation of Wnt signaling pathway negative regulation of G1/S transition of mitotic cell cycle negative regulation of cell growth positive regulation
FBXO7 (1,464 words) [view diff] exact match in snippet view article find links to article
protein-containing complex Biological process negative regulation of G1/S transition of mitotic cell cycle protein targeting to mitochondrion negative regulation
Bcl-2 (4,646 words) [view diff] exact match in snippet view article find links to article
homeostasis negative regulation of ossification negative regulation of G1/S transition of mitotic cell cycle positive regulation of smooth muscle cell migration
Start point (yeast) (1,695 words) [view diff] exact match in snippet view article
budding yeast, the transcription of over 200 genes is activated at the G1/S transition. The transcription of these G1/S genes is primarily regulated by two
APEX1 (1,319 words) [view diff] exact match in snippet view article find links to article
response to DNA damage stimulus DNA recombination positive regulation of G1/S transition of mitotic cell cycle negative regulation of smooth muscle cell migration
BCK2 (1,015 words) [view diff] exact match in snippet view article find links to article
and MBF complexes, which includes protein Swi6, regulate late G1 and G1/S transition genes. Overexpression of Bck2 in Swi6-null cells resulted in changes
APEX1 (1,319 words) [view diff] exact match in snippet view article find links to article
response to DNA damage stimulus DNA recombination positive regulation of G1/S transition of mitotic cell cycle negative regulation of smooth muscle cell migration
EIF4EBP1 (2,696 words) [view diff] exact match in snippet view article find links to article
receptor signaling pathway cellular response to dexamethasone stimulus G1/S transition of mitotic cell cycle response to ischemia lung development negative
RPTOR (3,504 words) [view diff] exact match in snippet view article find links to article
of protein serine/threonine kinase activity positive regulation of G1/S transition of mitotic cell cycle regulation of macroautophagy cellular response
HYAL1 (2,078 words) [view diff] exact match in snippet view article find links to article
cell adhesion hyaluronan metabolic process positive regulation of G1/S transition of mitotic cell cycle carbohydrate metabolic process response to virus
CUL3 (2,387 words) [view diff] exact match in snippet view article find links to article
ubiquitin-proteasome system post-translational protein modification transport G1/S transition of mitotic cell cycle SCF-dependent proteasomal ubiquitin-dependent
JADE1 (6,184 words) [view diff] exact match in snippet view article find links to article
transcription, DNA-templated histone H4-K5 acetylation negative regulation of G1/S transition of mitotic cell cycle negative regulation of cell growth histone H3
Branched chain amino acid transaminase 1 (891 words) [view diff] exact match in snippet view article find links to article
biosynthetic process branched-chain amino acid catabolic process valine biosynthetic process G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Telomerase reverse transcriptase (5,301 words) [view diff] exact match in snippet view article find links to article
cellular senescence response to cadmium ion positive regulation of G1/S transition of mitotic cell cycle beta-catenin-TCF complex assembly negative regulation
Oncovirus (6,056 words) [view diff] exact match in snippet view article find links to article
specific ubiquitination of p53. Rb is inactivated (thereby allowing the G1/S transition to progress unimpeded) by different but analogous viral oncoproteins
Proliferating cell nuclear antigen (6,158 words) [view diff] exact match in snippet view article find links to article
positive regulation of DNA repair regulation of transcription involved in G1/S transition of mitotic cell cycle positive regulation of DNA replication response
GPNMB (2,138 words) [view diff] exact match in snippet view article find links to article
cascade negative regulation of neuron death negative regulation of G1/S transition of mitotic cell cycle cell adhesion regulation of signaling receptor
KLF4 (6,943 words) [view diff] exact match in snippet view article find links to article
pri-miRNA transcription by RNA polymerase II negative regulation of G1/S transition of mitotic cell cycle positive regulation of transcription, DNA-templated
PINX1 (2,574 words) [view diff] exact match in snippet view article find links to article
Knockdown PINX1 led to increased cell proliferation and accelerated G1/S transition. PinX1 in other cancers: Ovarian PINX1 in 100% of normal ovarian tissue
Epidermal growth factor receptor (6,879 words) [view diff] exact match in snippet view article find links to article
signaling pathway positive regulation of canonical Wnt signaling pathway positive regulation of G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
CDKN1B (5,152 words) [view diff] exact match in snippet view article find links to article
cycle negative regulation of cyclin-dependent protein serine/threonine kinase activity G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
KHDRBS1 (2,812 words) [view diff] exact match in snippet view article find links to article
protein complex oligomerization regulation of alternative mRNA splicing, via spliceosome G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Schizosaccharomyces pombe (6,047 words) [view diff] no match in snippet view article find links to article
phase of the cell cycle for an extended period (as a consequence, G1-S transition is tightly controlled), while S. pombe remains in the G2 phase of the
Cellular senescence (6,395 words) [view diff] exact match in snippet view article find links to article
inhibits transcription of downstream target genes involved in the G1/S transition. As part of a feedback loop, increased phosphorylation of Rb increases
Endoreduplication (2,989 words) [view diff] no match in snippet view article find links to article
Roles for the E2F-DP Transcription Factor and Cyclin E during the G1-S Transition". Molecular and Cellular Biology. 18 (1): 141–151. doi:10.1128/MCB
Gcn2 (2,065 words) [view diff] exact match in snippet view article find links to article
et al. (March 2007). "A novel checkpoint mechanism regulating the G1/S transition". Genes & Development. 21 (6): 649–654. doi:10.1101/gad.421807. PMC 1820939
Allograft inflammatory factor 1 (2,817 words) [view diff] exact match in snippet view article find links to article
bundle assembly microglial cell activation positive regulation of G1/S transition of mitotic cell cycle actin filament polymerization negative regulation
EIF4E (8,380 words) [view diff] exact match in snippet view article find links to article
regulation of autophagy cellular response to dexamethasone stimulus G1/S transition of mitotic cell cycle regulation of translation at postsynapse, modulating
EZH2 (5,393 words) [view diff] exact match in snippet view article find links to article
activity negative regulation of gene expression negative regulation of G1/S transition of mitotic cell cycle histone H3-K27 methylation positive regulation
Proteasome (12,671 words) [view diff] no match in snippet view article find links to article
the adaptor protein, Skp2, which prevents SCF activity before the G1-S transition. Individual components of the 19S particle have their own regulatory
RIPK1 (4,148 words) [view diff] exact match in snippet view article find links to article
regulation of production of miRNAs involved in gene silencing by miRNA negative regulation of G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
STAU1 (2,556 words) [view diff] exact match in snippet view article find links to article
of E2F1 mRNA, which played a part in its translation and promotes G1/S transition. Thus, STAU1 expression is associated with proper splicing and expression
SAAL1 (2,146 words) [view diff] exact match in snippet view article find links to article
were stimulated by TNF-α. Stability assays reveal that SAAL1 promotes G1/S transition via CDK6 mRNA stabilization. This finding was corroborated by SAAL1
Eukaryotic DNA replication (14,643 words) [view diff] exact match in snippet view article find links to article
protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells". Molecular and Cellular Biology. 19 (7): 5083–5095