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Longer titles found: Programmed cell death protein 1 (view)

searching for Programmed cell death 265 found (996 total)

Inhibitor of apoptosis (1,524 words) [view diff] exact match in snippet view article find links to article

of proteins that mainly act on the intrinsic pathway that block programmed cell death, which can frequently lead to cancer or other effects for the cell

Protein serine/threonine phosphatase (222 words) [view diff] exact match in snippet view article find links to article

regulates many cellular pathways involved in cell proliferation, programmed cell death (apoptosis), embryonic development, and cell differentiation. There

H. Robert Horvitz (2,139 words) [view diff] exact match in snippet view article find links to article

discoveries concerning the genetic regulation of organ development and programmed cell death" were "important for medical research and have shed new light on

PDCD4 (1,041 words) [view diff] exact match in snippet view article find links to article

Programmed cell death protein 4 is a protein that in humans is encoded by the PDCD4 gene. It is one of the targets of an oncomiR, MIRN21. This gene encodes

Bcl-2 family (2,160 words) [view diff] exact match in snippet view article find links to article

family is most notable for their regulation of apoptosis, a form of programmed cell death, at the mitochondrion. The Bcl-2 family proteins consists of members

Bcl-xL (918 words) [view diff] exact match in snippet view article find links to article

cytochrome c, which leads to caspase activation and ultimately, programmed cell death. It is a well-established concept in the field of apoptosis that

Durvalumab (1,668 words) [view diff] exact match in snippet view article find links to article

kappa (IgG1κ) monoclonal antibody that blocks the interaction of programmed cell death ligand 1 (PD-L1) with the PD-1 (CD279).[medical citation needed]

Elesclomol (653 words) [view diff] exact match in snippet view article find links to article

Elesclomol (INN, codenamed STA-4783) is a drug that triggers apoptosis (programmed cell death) in cancer cells. It is being developed by Synta Pharmaceuticals

CAMK (886 words) [view diff] exact match in snippet view article find links to article

responding genes. CAMK also works to regulate the cell life cycle (i.e. programmed cell death), rearrangement of the cell's cytoskeletal network, and mechanisms

Nuclease S1 (842 words) [view diff] exact match in snippet view article find links to article

prokaryotes and eukaryotes and are thought to be associated in programmed cell death and also in tissue differentiation. Furthermore, they are secreted

PDCD10 (1,337 words) [view diff] exact match in snippet view article find links to article

Programmed cell death protein 10 is a protein that in humans is encoded by the PDCD10 gene. This gene encodes a protein, originally identified in a premyeloid

TNF receptor superfamily (501 words) [view diff] exact match in snippet view article find links to article

the fact that they seemed to play an important role in apoptosis (programmed cell death), although they are now known to play other roles as well. In the

PDCD5 (988 words) [view diff] exact match in snippet view article find links to article

Programmed cell death protein 5 is a protein, originally identified as an apoptosis-accelerating protein, that in humans is encoded by the PDCD5 gene

PDCD6IP (1,242 words) [view diff] exact match in snippet view article find links to article

Programmed cell death 6-interacting protein also known as ALIX is a protein that in humans is encoded by the PDCD6IP gene. This gene encodes a protein

3,4-Dihydroxyphenylacetaldehyde (253 words) [view diff] exact match in snippet view article find links to article

mitochondria were highly potent in inducing a pathway associated with programmed cell death (or apoptosis), permeability transition. This suggests the cytotoxity

Necroptosis (1,667 words) [view diff] exact match in snippet view article find links to article

cellular damage or infiltration by pathogens, in contrast to orderly, programmed cell death via apoptosis. The discovery of necroptosis showed that cells can

ABCA3 (954 words) [view diff] exact match in snippet view article find links to article

development of resistance to xenobiotics and engulfment during programmed cell death. Mutations in ABCA3 are associated to cataract-microcornea syndrome

PDCD6 (1,245 words) [view diff] exact match in snippet view article find links to article

Programmed cell death protein 6 is a protein that in humans is encoded by the PDCD6 gene. This gene encodes a calcium-binding protein belonging to the

Cell fate determination (2,721 words) [view diff] exact match in snippet view article find links to article

include cell proliferation, differentiation, cellular movement and programmed cell death. Each cell in an embryo receives molecular signals from neighboring

Pyrin domain (1,163 words) [view diff] exact match in snippet view article find links to article

Proteins containing a pyrin domain are frequently involved in programmed cell death processes including pyroptosis and apoptosis. Proteins that possess

PDCD7 (466 words) [view diff] exact match in snippet view article find links to article

Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene. This gene encodes a protein with sequence similarity to a mouse

MAPK phosphatase (1,883 words) [view diff] exact match in snippet view article find links to article

homeostasis. This can involve gene regulation, cell proliferation, programmed cell death and stress responses. MAPK phosphatases are therefore important

Jerry Adams (593 words) [view diff] exact match in snippet view article find links to article

PhD student, David Vaux, made the connection between apoptosis (programmed cell death) and cancer, while studying the bcl-2 gene in follicular lymphoma

Tetrahydrobiopterin (2,819 words) [view diff] no match in snippet view article find links to article

Tetrahydrobiopterin (BH4, THB), also known as sapropterin (INN), is a cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation

PTPN13 (1,227 words) [view diff] exact match in snippet view article find links to article

through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein

Bogdan Đuričić (162 words) [view diff] exact match in snippet view article find links to article

chief area of scientific research was in molecular mechanisms of programmed cell death and biochemistry of ischemia. In 1974, he graduated from the Belgrade

DNASE1L1 (1,676 words) [view diff] exact match in snippet view article find links to article

300-base pair pieces represents the final step in the execution of programmed cell death (apoptosis). Cells can then no longer perform cell division and

SIVA1 (1,004 words) [view diff] exact match in snippet view article find links to article

gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis

Cryoablation (2,461 words) [view diff] exact match in snippet view article find links to article

ischemia and cell death; and induction of apoptosis, the so-called programmed cell death cascade. The most common application of cryoablation is to ablate

Ced-9 (1,798 words) [view diff] exact match in snippet view article find links to article

a gene found in Caenorhabditis elegans that inhibits/represses programmed cell death (apoptosis). The gene was discovered while searching for mutations

Receptor editing (283 words) [view diff] exact match in snippet view article find links to article

of self reactive immature B-cells, in order to rescue them from programmed cell death, called apoptosis. It is thought that 20-50% of all peripheral naive

ADP/ATP translocase 2 (1,932 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

Reactive oxygen species (8,480 words) [view diff] exact match in snippet view article find links to article

either protect against singlet oxygen induced toxicity or initiate programmed cell death. Levels of jasmonate play a key role in the decision between cell

TIA1 (1,282 words) [view diff] exact match in snippet view article find links to article

can bind the 5'TOP sequence of 5'TOP mRNAs. It is associated with programmed cell death (apoptosis) and regulates alternative splicing of the gene encoding

Immunoglobulin V-set domain (367 words) [view diff] exact match in snippet view article find links to article

molecules (JAM); in tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1). Immunoglobulin V-set, subgroup InterPro: IPR003596

Promyelocytic leukemia protein (4,053 words) [view diff] exact match in snippet view article find links to article

number of regulatory cellular functions, including involvement in programmed cell death, genome stability, antiviral effects and controlling cell division

Rosalind and Morris Goodman Cancer Research Centre (158 words) [view diff] exact match in snippet view article find links to article

signalling • Metabolism and cancer • DNA damage and apoptosis (programmed cell death) As of 2014, they are made up of 26 full faculty members and 31

ZFY (946 words) [view diff] exact match in snippet view article find links to article

spermatogenesis, wrongful expression of either Zfy1 or Zfy2 results in programmed cell death, apoptosis, at the mid-pachytene checkpoint. In mice, Zfy genes

AKTIP (850 words) [view diff] exact match in snippet view article find links to article

these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase

FAF1 (934 words) [view diff] exact match in snippet view article find links to article

of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein

Checkpoint inhibitor (2,093 words) [view diff] exact match in snippet view article find links to article

the molecules CTLA4, PD-1, and PD-L1. PD-1 is the transmembrane programmed cell death 1 protein (also called PDCD1 and CD279), which interacts with PD-L1

Polyamine (1,612 words) [view diff] exact match in snippet view article find links to article

hormone. In addition, they are directly involved in regulation of programmed cell death. Polyamines promote homologous recombination (HR)-mediated double-strand

Shigekazu Nagata (583 words) [view diff] exact match in snippet view article find links to article

biochemist, best known for research on apoptosis, the process of programmed cell death occurring in multi-cellular organisms. Nagata identified Interferon

Stanley J. Korsmeyer (1,357 words) [view diff] exact match in snippet view article find links to article

cancer-causing genes, providing the first example of how interfering with programmed cell death could lead to cancer development. Korsmeyer authored over 250 scientific

Reactome (1,585 words) [view diff] exact match in snippet view article find links to article

innate and acquired immune function, transcriptional regulation, programmed cell death and classical intermediary metabolism. The pathways represented

Stefanie Dimmeler (856 words) [view diff] exact match in snippet view article find links to article

Leibniz Prize of the German Research Foundation for her work on the programmed cell death of endothelial cells. Since 2008 she has led the Institute for Cardiovascular

Focal adhesion targeting region (363 words) [view diff] exact match in snippet view article find links to article

FAK-related protein kinase PTK2B/FAK2/PYK2, and alpha-catenin, vinculin, Programmed cell death protein 10 (PDCD10)/Cerebral Cavernous Malformation protein 3 (CCM3)

13-Methyltetradecanoic acid (1,078 words) [view diff] exact match in snippet view article find links to article

13-Methyltetradecanoic acid (13-MTD) is a fatty acid known to induce apoptosis or “programmed cell death” of certain human cancer cells. 13-MTD was originally purified from

Caenorhabditis elegans (10,541 words) [view diff] exact match in snippet view article find links to article

a very popular model system for studying developmental biology. Programmed cell death (apoptosis) eliminates many additional cells (131 in the hermaphrodite

ATC code L01 (877 words) [view diff] no match in snippet view article find links to article

ATC code L01 Antineoplastic agents is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes

Granzyme A (1,629 words) [view diff] exact match in snippet view article find links to article

residues. In CTL-targeted cells, it activates caspase-independent programmed cell death pathways that are unique and parallel to that of Granzyme B, although

Emad Alnemri (237 words) [view diff] case mismatch in snippet view article find links to article

his thesis was on "Molecular Mechanisms of Glucocorticoid-induced Programmed Cell Death in Lymphoid Tissues", under advisor Gerald Litwack. He has held

Cell lineage (1,530 words) [view diff] exact match in snippet view article find links to article

neurons. This research also led to the initial observations of programmed cell death, or apoptosis. After mapping various sections of the C. elegans'

Sjögren syndrome (9,010 words) [view diff] exact match in snippet view article find links to article

lymphomagenesis (origin of lymphoma). Dysregulation of apoptosis (programmed cell death) is believed to play a role in the pathogenesis of a variety of

Spermatogonium (292 words) [view diff] exact match in snippet view article find links to article

response, exposure of spermatogonia to doxorubicin can also induce programmed cell death (apoptosis). Transverse section of a tubule of the testis of a rat

Junying Yuan (1,649 words) [view diff] exact match in snippet view article find links to article

behind programmed cell death in the nematode Caenorhabditis elegans. She identified the proteins ced-3 and ced-4 as drivers behind programmed cell death in

PLSCR3 (1,030 words) [view diff] exact match in snippet view article find links to article

membrane protein that is rich in proline and integral in apoptosis, or programmed cell death. The regulation of apoptosis is critical for both cell development

Volasertib (1,758 words) [view diff] exact match in snippet view article find links to article

programmed cell death, however, in normal cells inhibition of PLK1 only causes temporary, reversible G1 and G2 arrest without programmed cell death.

DAPK1 (1,170 words) [view diff] exact match in snippet view article find links to article

protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent

Cryptic self epitopes (156 words) [view diff] exact match in snippet view article find links to article

developing T-cell and signal those "self-reactive" T-cells to die via programmed cell death (apoptosis) and thereby deletion from the T cell repertoire, preventing

ABT-737 (649 words) [view diff] exact match in snippet view article find links to article

family is most notable for their regulation of apoptosis, a form of programmed cell death, at the mitochondrion; Bcl-2 and Bcl-xL are anti-apoptotic proteins

Arenobufagin (1,536 words) [view diff] exact match in snippet view article find links to article

a high Bax/Bcl-2 ratio, which is associated with apoptosis, or programmed cell death. Bax translocation from cytosol to mitochondria was also found to

Par stability determinant (547 words) [view diff] exact match in snippet view article find links to article

Franch T, Pedersen K, Mikkelsen ND (1997). "Antisense RNA-regulated programmed cell death". Annu. Rev. Genet. 31: 1–31. doi:10.1146/annurev.genet.31.1.1.

Identification of cell death (1,397 words) [view diff] exact match in snippet view article find links to article

and proteins and a loss of compartmentalization. Apoptosis, or programmed cell death, is generally characterized by distinct morphological characteristics

Angiotensin II receptor type 2 (1,722 words) [view diff] exact match in snippet view article find links to article

mediated by the renin–angiotensin system. This receptor mediates programmed cell death (apoptosis). Consistent with its apoptotic function, angiotensin

Hok/sok system (1,446 words) [view diff] exact match in snippet view article find links to article

Hayes F (September 2003). "Toxins-antitoxins: plasmid maintenance, programmed cell death, and cell cycle arrest". Science. 301 (5639): 1496–9. Bibcode:2003Sci

Calliphora vomitoria (3,201 words) [view diff] exact match in snippet view article find links to article

the fly, such as cell death. While it is commonly believed that programmed cell death and apoptosis are the same, they are not always so. At the beginning

Mitosis (7,313 words) [view diff] exact match in snippet view article find links to article

errors during mitosis can induce mitotic catastrophe, apoptosis (programmed cell death) or cause mutations. Certain types of cancers can arise from such

Tropomyosin receptor kinase A (3,264 words) [view diff] exact match in snippet view article find links to article

differentiation, neural proliferation, nociceptor response, and avoidance of programmed cell death. The binding of NGF to TrkA leads to a ligand-induced dimerization

Immunologic checkpoint (385 words) [view diff] exact match in snippet view article find links to article

CD152), which is an inhibitory receptor found on immune cells and programmed cell death 1 (CD279), which has an important role in down-regulating the immune

ADP/ATP translocase 4 (1,608 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

Cavernous hemangioma (3,660 words) [view diff] exact match in snippet view article find links to article

genes – K-Rev interaction trapped 1 (ССМ1), Malcavernin (CCM2) and Programmed cell death protein 10 (ССМ3) – have been identified as having mutations thought

Imatinib (6,513 words) [view diff] exact match in snippet view article find links to article

the Bcr-Abl tyrosine-kinase. This can slow growth or result in programmed cell death of certain types of cancer cells. Imatinib was approved for medical

Megagametogenesis (1,074 words) [view diff] exact match in snippet view article find links to article

cells are involved with nourishing the embryo, but often undergo programmed cell death before fertilization occurs. Cell plates form around the antipodal

ZBP1 (831 words) [view diff] exact match in snippet view article find links to article

sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways". Science Immunology. 1 (2): aag2045. doi:10.1126/sciimmunol

Giardiasis (5,525 words) [view diff] exact match in snippet view article find links to article

changes to the microvillus, increased intestinal permeability, and programmed cell death of small intestinal epithelial cells. Both trophozoites and cysts

VDAC3 (2,552 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

Chris J. Leaver (1,116 words) [view diff] exact match in snippet view article find links to article

from the mitochondria to the cytosol occurs during heat-induced programmed cell death in cucumber plants". FEBS Letters. 463 (1–2): 151–154. doi:10

MAPK14 (5,259 words) [view diff] exact match in snippet view article find links to article

implicated in diverse cellular functions, from gene expression to programmed cell death through a network of signaling molecules and transcription factors

Li–Fraumeni syndrome (2,402 words) [view diff] exact match in snippet view article find links to article

instability. Also these cells have reduced ability to undergo apoptosis (programmed cell death) in response to DNA damage and thus are resistant to the ordinary

DNASE1L3 (724 words) [view diff] exact match in snippet view article find links to article

process DNA catabolic process programmed cell death involved in cell development apoptotic process programmed cell death apoptotic DNA fragmentation DNA

VDAC2 (2,653 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

Li–Fraumeni syndrome (2,402 words) [view diff] exact match in snippet view article find links to article

instability. Also these cells have reduced ability to undergo apoptosis (programmed cell death) in response to DNA damage and thus are resistant to the ordinary

Mixed lineage kinase domain like pseudokinase (774 words) [view diff] exact match in snippet view article find links to article

critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3)

Guanylate-binding protein (1,261 words) [view diff] exact match in snippet view article find links to article

pathogens and causing bacterial cell lysis, GBP1 can also cause host-programmed cell death. The GBP family of proteins is highly conserved among many different

Lymphoproliferative disorders (767 words) [view diff] exact match in snippet view article find links to article

shown to play a central role in the physiological regulation of programmed cell death. Normally, stimulation of recently activated T cells by antigen

ACER3 (326 words) [view diff] exact match in snippet view article find links to article

population proliferation inflammatory response myelination regulation of programmed cell death ceramide catabolic process lipid metabolism sphingolipid metabolic

Plant embryonic development (2,485 words) [view diff] exact match in snippet view article find links to article

continued growth of the cotyledons and axis elongation. In addition, programmed cell death must occur during this stage. This is carried out throughout the

Dap (487 words) [view diff] exact match in snippet view article find links to article

human gene that encodes death-associated proteins, which mediate programmed cell death Diamidophosphate, phosphorylating compound Diaminopimelic acid,

Webbed toes (689 words) [view diff] exact match in snippet view article find links to article

webbed fingers and webbed toes. Syndactyly occurs when apoptosis or programmed cell death during gestation is absent or incomplete. Webbed toes occur most

Smoker's face (665 words) [view diff] case mismatch in snippet view article find links to article

Depletion, Opening of Mitochondrial Permeability Transition, and Programmed Cell Death". Plant Physiology. 128 (4): 1271–1281. doi:10.1104/pp.010999. PMC 154255

IAP (446 words) [view diff] exact match in snippet view article find links to article

Inhibitor of apoptosis, a protein family involved in the suppression of programmed cell death (apoptosis) Integrated automation platform Integrin Associated Protein

Ced-12 (1,471 words) [view diff] exact match in snippet view article find links to article

apoptosis has been triggered in a cell. Apoptosis, also known as programmed cell death, activates during development as well as in situations where a cell

HMGA (407 words) [view diff] exact match in snippet view article find links to article

formation of 6-O-methylguanine) this causes an increase in apoptosis (programmed cell death). However, cells with diminished activity for either proteins HMGA1

Michael Travisano (982 words) [view diff] exact match in snippet view article find links to article

higher rates of programmed cell death, as is seen in the protective boundary of skin cells. In snowflake yeast, programmed cell death is an adaptation

Ischemic cell death (1,082 words) [view diff] exact match in snippet view article find links to article

caused by a failure in ion transporter function. Apoptosis, or programmed cell death involves a series of cell shrinking processes, beginning with cell

EIF4G2 (1,114 words) [view diff] exact match in snippet view article find links to article

4G isolated as a putative modulator of gamma interferon-induced programmed cell death". Mol. Cell. Biol. 17 (3): 1615–25. doi:10.1128/mcb.17.3.1615. PMC 231887

PKM2 (4,865 words) [view diff] exact match in snippet view article find links to article

analogue, H2O2, or UV light has been linked with caspase-independent programmed cell death. PKM2 is expressed in most human tumors. Initially, a switch from

ENDOG (2,404 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

Egg cell (1,457 words) [view diff] exact match in snippet view article find links to article

and organelles to the oocytes. This transfer is followed by the programmed cell death (apoptosis) of the nurse cells. During oogenesis, 15 nurse cells

Richard Youle (614 words) [view diff] exact match in snippet view article find links to article

laboratory at NINDS, Youle then investigated molecular mechanisms of programmed cell death and the role of its regulation in the interaction between Bcl-2

Jasmonate (2,887 words) [view diff] exact match in snippet view article find links to article

mitochondria membranes and compromise the cell by causing apoptosis, or programmed cell death. JAs' roles in these processes are suggestive of methods by which

NPHP3 (590 words) [view diff] exact match in snippet view article find links to article

class of P-loop NTPases including animal and plant regulators of programmed cell death: multiple, complex domain architectures, unusual phyletic patterns

GSDMC (118 words) [view diff] exact match in snippet view article find links to article

microtubule organizing center cytosol plasma membrane membrane Biological process programmed cell death biological process pyroptosis Sources:Amigo / QuickGO

Efferocytosis (679 words) [view diff] exact match in snippet view article find links to article

atherosclerosis. deCathelineau AM, Henson PM (2003). "The final step in programmed cell death: phagocytes carry apoptotic cells to the grave". Essays in Biochemistry

TRPM7 (421 words) [view diff] exact match in snippet view article find links to article

magnesium ion homeostasis calcium-dependent cell-matrix adhesion programmed cell death phosphorylation actomyosin structure organization cation transport

Ageing (10,713 words) [view diff] exact match in snippet view article find links to article

may cause ageing. Programmed ageing should not be confused with programmed cell death (apoptosis). Obesity has been proposed to accelerate ageing, whereas

Heme C (892 words) [view diff] exact match in snippet view article find links to article

cytoplasmic cytochrome c, which must still contain heme C, leads to programmed cell death. Cytochrome c can be measured in human serum and can be used as

Cysteine protease (1,278 words) [view diff] exact match in snippet view article find links to article

other animals, they are responsible for senescence and apoptosis (programmed cell death), MHC class II immune responses, prohormone processing, and extracellular

Blocking antibody (718 words) [view diff] no match in snippet view article find links to article

function. Some new treatments hypothesize the blocking of PD-1, a programmed cell-death protein, which will result in longer-lived T-cells. The blocking

Interleukin 1 beta (3,305 words) [view diff] no match in snippet view article find links to article

abortively infected, where the virus gets detected inside the cell and a programmed cell-death, known as pyroptosis, kills the infected cell. Pyroptosis is mediated

Anti-dsDNA antibodies (2,924 words) [view diff] exact match in snippet view article find links to article

extracellular DNA. Apoptosis is the highly organised process of programmed cell death in which the cell degrades the nuclear DNA and signals for phagocytosis

Pib2 (1,007 words) [view diff] exact match in snippet view article find links to article

PMID 25735653. S2CID 11609431. van Doorn WG (October 2011). "Classes of programmed cell death in plants, compared to those in animals". Journal of Experimental

Gasdermin A (111 words) [view diff] exact match in snippet view article find links to article

perinuclear region of cytoplasm cytosol plasma membrane membrane Biological process programmed cell death apoptotic process pyroptosis Sources:Amigo / QuickGO

Inflammasome (7,817 words) [view diff] exact match in snippet view article find links to article

resulting from this cleavage induces a pro-inflammatory form of programmed cell death distinct from apoptosis, referred to as pyroptosis, which is responsible

Hugh McDevitt (624 words) [view diff] exact match in snippet view article find links to article

can trigger the onset of type-1 diabetes. "A normal process - programmed cell death - causes a normal response," McDevitt said. "But it does this in

Carcinogen (4,566 words) [view diff] exact match in snippet view article find links to article

in colon cells. Also 27 studies reported that bile acids cause programmed cell death (apoptosis). Increased apoptosis can result in selective survival

Death effector domain (2,408 words) [view diff] exact match in snippet view article find links to article

both life and death cell decisions. Apoptosis is a controlled and programmed cell death that confers advantages during an organism lifecycle. The extrinsic

Systemic acquired resistance (982 words) [view diff] exact match in snippet view article find links to article

effector triggered immunity (ETI). ETI often results in a form of programmed cell death (PCD), called hypersensitive response (HR). Pathogens can then evolve

Rohon–Beard cell (280 words) [view diff] exact match in snippet view article find links to article

2004). "Slow degeneration of zebrafish Rohon-Beard neurons during programmed cell death". Dev Dyn. 229 (1): 30–41. doi:10.1002/dvdy.10488. PMID 14699575

Corneal keratocyte (1,355 words) [view diff] exact match in snippet view article find links to article

process that attracts special attention. In a healthy cornea the programmed cell death is a rare occasion, but immediately after an injury to the uppermost

MARK4 (852 words) [view diff] exact match in snippet view article find links to article

midbody Biological process phosphorylation positive regulation of programmed cell death nervous system development protein phosphorylation microtubule bundle

Spontaneous remission (1,066 words) [view diff] exact match in snippet view article find links to article

explains the occurrence of spontaneous regression." Apoptosis (programmed cell death) and angiogenesis (growth of new blood vessels) are sometimes discussed

SOD2 (3,223 words) [view diff] exact match in snippet view article find links to article

mitochondrial death pathway and cardiac myocyte apoptosis signaling. Programmed cell death is a distinct genetic and biochemical pathway essential to metazoans

GSDMB (172 words) [view diff] exact match in snippet view article find links to article

cytoplasm cytosol plasma membrane membrane cellular component Biological process programmed cell death biological process pyroptosis Sources:Amigo / QuickGO

Nivolumab (4,777 words) [view diff] exact match in snippet view article find links to article

activated T cells. If another molecule, called programmed cell death 1 ligand 1 or programmed cell death 1 ligand 2 (PD-L1 or PD-L2), binds to PD-1, the

Chemotherapy (17,494 words) [view diff] exact match in snippet view article find links to article

to repair it, the DNA strands can break. This leads to a form of programmed cell death called apoptosis. Alkylating agents will work at any point in the

Aspergillus nidulans (767 words) [view diff] exact match in snippet view article find links to article

caspase-like proteases were isolated from A. nidulans samples under which programmed cell death had been induced. Findings such as these play a key role in determining

Bcl-2-like protein 1 (2,223 words) [view diff] case mismatch in snippet view article find links to article

INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE 1maz: X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH 1pq0: Crystal

ETS transcription factor family (1,020 words) [view diff] exact match in snippet view article find links to article

cell cycle control, cell migration, cell proliferation, apoptosis (programmed cell death) and angiogenesis. Multiple ETS factors have been found to be associated

Α-Eleostearic acid (478 words) [view diff] exact match in snippet view article find links to article

conjugated linoleic acid. The compound has been found to induce programmed cell death of fat cells, and of HL60 leukemia cells in vitro at a concentration

Pathophysiology of HIV/AIDS (1,841 words) [view diff] exact match in snippet view article find links to article

inflammasomes and inducing pyroptosis, a highly inflammatory form of programmed cell death. These findings cast CD4 T-cell death during HIV infection in a

Undercard (album) (215 words) [view diff] case mismatch in snippet view article

"Cruiserweights" "Only Existing Footage" "Communicating Doors" "Programmed Cell Death" "How I Left the Ministry" "Some Other Way" "Ambivalent Landscape

2002 in science (1,438 words) [view diff] exact match in snippet view article find links to article

discoveries concerning genetic regulation of organ development and programmed cell death" Turing Award: Ron Rivest, Adi Shamir, and Leonard Adleman Wollaston

POU4F2 (988 words) [view diff] exact match in snippet view article find links to article

regulation of transcription by RNA polymerase II positive regulation of programmed cell death negative regulation of cell differentiation positive regulation

Procarbazine (821 words) [view diff] exact match in snippet view article find links to article

Proliferating cancer cells need to replicate their DNA and undergo programmed cell death (apoptosis) in response to DNA strand breaks. Normal or non-proliferating

Conidium (1,777 words) [view diff] exact match in snippet view article find links to article

immunity in the lung relies on targeting fungal apoptosis-like programmed cell death". Science. 357 (6355): 1037–1041. Bibcode:2017Sci...357.1037S. doi:10

Avelumab (1,471 words) [view diff] exact match in snippet view article find links to article

death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). Formation of a PD-1/PD-L1 receptor/ligand complex leads

Caspase 2 (921 words) [view diff] exact match in snippet view article find links to article

ligand positive regulation of apoptotic process ectopic germ cell programmed cell death apoptotic signaling pathway neural retina development apoptotic

Antamanide (691 words) [view diff] exact match in snippet view article find links to article

to determine whether the antamanide also inhibits the apoptosis (programmed cell death) of human cervical carcinoma cells caused by the permeability transition

PPIF (1,594 words) [view diff] exact match in snippet view article find links to article

regulation of apoptotic process cellular response to calcium ion programmed cell death negative regulation of intrinsic apoptotic signaling pathway negative

Prolidase deficiency (1,157 words) [view diff] no match in snippet view article find links to article

proposed that the buildup of non-degraded dipeptides might induce programmed cell-death (apoptosis), whereafter the cell's contents would be expelled into

Central nervous system cavernous hemangioma (1,945 words) [view diff] exact match in snippet view article find links to article

the most recently identified CCM gene . CCM3 is known as PDCD10 (programmed cell death 10), which was initially identified as a gene that is up-regulated

Pioneer neuron (350 words) [view diff] no match in snippet view article find links to article

appropriate target. In many systems pioneer neurons are eliminated by programmed cell-death and are not present in the adult. Neural development Meyer G, Soria

Proteasome (12,671 words) [view diff] exact match in snippet view article find links to article

and external signals can lead to the induction of apoptosis, or programmed cell death. The resulting deconstruction of cellular components is primarily

STAT5 (1,215 words) [view diff] exact match in snippet view article find links to article

with: Controlled cell growth and division, or cell proliferation Programmed cell death, or apoptosis Cell specialization, or differentiation and Inflammation

School of Medical Sciences, University of Manchester (1,087 words) [view diff] exact match in snippet view article find links to article

discoveries concerning 'genetic regulation of organ development and programmed cell death'. Raymond Tallis, gerontologist. Nesta Wells, first British female

Caspase-2 (379 words) [view diff] exact match in snippet view article find links to article

Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death". Cell. 78 (5): 739–50. doi:10.1016/S0092-8674(94)90422-7. PMID 8087842

Growth factor (1,131 words) [view diff] exact match in snippet view article find links to article

are used as "death" signals; they cause target cells to undergo programmed cell death or apoptosis. The nerve growth factor (NGF) was first discovered

PGAM5 (107 words) [view diff] exact match in snippet view article find links to article

membrane Biological process protein dephosphorylation necroptosis programmed cell death dephosphorylation positive regulation of GTPase activity macroautophagy

Phycodnaviridae (9,384 words) [view diff] exact match in snippet view article find links to article

viral sphingolipids produced during the lytic stage are involved in programmed cell death in coccolithophore populations. A high correlation was found between

Obligate parasite (2,109 words) [view diff] exact match in snippet view article find links to article

to reduce the replication and spread of pathogens is apoptosis (programmed cell death). Some obligate parasites have developed ways to suppress this phenomenon

EVA1A (210 words) [view diff] exact match in snippet view article find links to article

Aliases EVA1A, FAM176A, TMEM166, eva-1 homolog A, regulator of programmed cell death External IDs MGI: 2385247 HomoloGene: 12969 GeneCards: EVA1A Wikidata

Ancrod (1,789 words) [view diff] exact match in snippet view article find links to article

that the substance has interesting apoptotic properties (causing programmed cell death), which remain to be explored. The half-life of ancrod is 3 to 5

Trichostatin A (523 words) [view diff] case mismatch in snippet view article find links to article

Clinical Significance in Cancer: HDAC Inhibitor-Induced Apoptosis". Programmed Cell Death in Cancer Progression and Therapy. Advances in Experimental Medicine

SPATA2 (423 words) [view diff] exact match in snippet view article find links to article

response regulation of necroptotic process protein K63-linked deubiquitination protein linear deubiquitination programmed cell death Sources:Amigo / QuickGO

Omigapil (2,218 words) [view diff] exact match in snippet view article find links to article

Kingdom at Great Ormond Street Hospital (UCL). Omigapil inhibits programmed cell death (apoptosis) through the enzymes glyceraldehyde 3-phosphate dehydrogenase

Peptidomimetic (1,365 words) [view diff] exact match in snippet view article find links to article

cells, an approach known as targeted chemotherapy, by inducing programmed cell death by a process called apoptosis. The following two examples mimic

Heterophyes heterophyes (1,565 words) [view diff] exact match in snippet view article find links to article

NF-jB. Caspase-3 and NF-jB are protein that are essential to induce programmed cell death, apoptosis. Diagnosis done by stool examination is difficult when

IFI16 (1,371 words) [view diff] exact match in snippet view article find links to article

helper CD4 T cells by pyroptosis, a highly inflammatory form of programmed cell death. Recently, it has been shown how IFI16, once extracellularly released

Embryomics (2,179 words) [view diff] exact match in snippet view article find links to article

into mature adult somatic cell types, or which disappear due to programmed cell death (apoptosis). The entire process of embryogenesis can be described

DNAJC3 (1,492 words) [view diff] exact match in snippet view article find links to article

processes. It plays an important role during embryonal development as programmed cell death and accompanies a variety of normal involutional processes in which

LARP6 (354 words) [view diff] exact match in snippet view article find links to article

novel member of the Lupus Antigen family, is induced during the programmed cell death of skeletal muscles in the moth Manduca sexta". Gene. 393 (1–2):

Zeta toxin protein domain (338 words) [view diff] exact match in snippet view article find links to article

, Shoeman, R.L. and Meinhart, A. (2011). "A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis"

John Savill (822 words) [view diff] exact match in snippet view article find links to article

"Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages". Journal

Chromosome 19 (2,547 words) [view diff] exact match in snippet view article find links to article

receptor PALM: encoding protein Paralemmin PDCD5: encoding protein Programmed cell death protein 5 PEX11G: peroxisomal biogenesis factor 11 gamma PGK1P2:

Finger (2,884 words) [view diff] exact match in snippet view article find links to article

Garcia-Martinez, D. Macias et al: Internucleosomal DNA fragmentation and programmed cell death (apoptosis) in the interdigital tissue of the embryonic chick leg

PHLDA1 (616 words) [view diff] case mismatch in snippet view article find links to article

"TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia"

Mebendazole (1,543 words) [view diff] exact match in snippet view article find links to article

which allows pro-apoptotic protein Bax to dimerize and initiate programmed cell death. Mebendazole is available as a generic medication. Mebendazole is

Chromosome 3 (1,978 words) [view diff] exact match in snippet view article find links to article

PCCB: propionyl Coenzyme A carboxylase, beta polypeptide PDCD10: programmed cell death 10 PIK3CA: phosphoinositide-3-kinase, catalytic, alpha polypeptide

DAD1 (695 words) [view diff] exact match in snippet view article find links to article

cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared

Erythropoiesis (1,802 words) [view diff] exact match in snippet view article find links to article

Föller; Stephan M. Huber; Florian Lang (August 2008). "Erythrocyte programmed cell death". IUBMB Life. 60 (10): 661–668. doi:10.1002/iub.106. PMID 18720418

Prolactin receptor (1,865 words) [view diff] exact match in snippet view article find links to article

proliferation, migration, intracellular ion concentration and inhibit programmed cell death (apoptosis). PRLRs also have functions in the second messenger cascades

Integrin beta 5 (1,273 words) [view diff] exact match in snippet view article find links to article

Pasqualini Renata (May 2003). "Alpha v beta 5 integrin-dependent programmed cell death triggered by a peptide mimic of annexin V". Mol. Cell. 11 (5): 1151–62

Actibind (1,363 words) [view diff] exact match in snippet view article find links to article

unwanted cells that have been damaged beyond repair; the process of programmed cell death. Apoptosis' dysregulation can trigger irregular responses that contribute

HAVCR2 (2,900 words) [view diff] exact match in snippet view article find links to article

checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3)

Retinoic acid receptor beta (1,275 words) [view diff] exact match in snippet view article find links to article

organism growth embryonic eye morphogenesis positive regulation of programmed cell death negative regulation of apoptotic process negative regulation of

Retinoic acid receptor gamma (1,208 words) [view diff] exact match in snippet view article find links to article

positive regulation of apoptotic process positive regulation of programmed cell death cellular response to leukemia inhibitory factor multicellular organism

Nociceptor (2,854 words) [view diff] exact match in snippet view article find links to article

abdomen: origins, dendritic morphology, and segment- and age-dependent programmed cell death". Neural Development. 4 (1): 37. doi:10.1186/1749-8104-4-37. ISSN 1749-8104

Nuclear bodies (1,585 words) [view diff] exact match in snippet view article find links to article

it is targeted to dots. whereas overexpression of PML results in programmed cell death. One hypothesized function of the dots is as a 'nuclear dump' or

Phytoalexin (1,762 words) [view diff] exact match in snippet view article find links to article

surrounding the site of infection are signaled to undergo apoptosis, or programmed cell death, in order to prevent the spread of the pathogen to the rest of the

DNA damage-inducible transcript 3 (5,505 words) [view diff] exact match in snippet view article find links to article

PMC 4284148. PMID 24994655. Elmore S (June 2007). "Apoptosis: a review of programmed cell death". Toxicologic Pathology. 35 (4): 495–516. doi:10.1080/01926230701320337

APBB2 (655 words) [view diff] exact match in snippet view article find links to article

FE65-like protein 1 regulates both apoptotic and caspase-independent programmed cell death mediated by tumor necrosis factor". Biochem. Biophys. Res. Commun

Betulinic acid (1,909 words) [view diff] exact match in snippet view article find links to article

PMID 12118187. Tan Y, Yu R, Pezzuto JM (July 2003). "Betulinic acid-induced programmed cell death in human melanoma cells involves mitogen-activated protein kinase

Ubiquitin carboxy-terminal hydrolase L1 (2,637 words) [view diff] exact match in snippet view article find links to article

Uchl1 increases the susceptibility of pancreatic beta-cells to programmed cell death, indicating that this protein plays a protective role in neuroendocrine

Ben Barres (3,351 words) [view diff] exact match in snippet view article find links to article

connections with their targets. These studies investigated how this programmed cell death, apoptosis, occurred in such a tremendous scale. Additionally, he

UDP-N-acetylglucosamine kinase (289 words) [view diff] exact match in snippet view article find links to article

Gebhardt M, Shoeman RL, Meinhart A (March 2011). "A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis"

PAX2 (1,868 words) [view diff] exact match in snippet view article find links to article

system development cell fate determination negative regulation of programmed cell death vestibulocochlear nerve formation camera-type eye development metanephric

Trichothecene (5,601 words) [view diff] exact match in snippet view article find links to article

which inevitably leads to oxidative stress and induction of the programmed cell death pathway, apoptosis. The induction of apoptosis in cells with high

Anal cancer (2,608 words) [view diff] exact match in snippet view article find links to article

speculate that smoking interferes with a process called apoptosis, or programmed cell death, which helps rid the body of abnormal cells that could turn cancerous

DNA fragmentation (1,498 words) [view diff] exact match in snippet view article find links to article

fragmentation is a natural fragmentation that cells perform in apoptosis (programmed cell death). DNA fragmentation is a biochemical hallmark of apoptosis. In dying

Antimutagen (1,032 words) [view diff] exact match in snippet view article find links to article

nucleotide excision repair such as XPA and XPC; Selenium: Induces programmed cell death via many signalling pathways as well as protects the cells against

ANKRD25 (527 words) [view diff] exact match in snippet view article find links to article

of G1/S transition of mitotic cell cycle negative regulation of programmed cell death negative regulation of intracellular estrogen receptor signaling

RAB9A (881 words) [view diff] exact match in snippet view article find links to article

"A tomato homologue of the human protein PIRIN is induced during programmed cell death". Plant Mol. Biol. 46 (4): 459–68. doi:10.1023/A:1010618515051.

Chemical modification (1,476 words) [view diff] exact match in snippet view article find links to article

important during cell signaling, removing misfolded proteins, and programmed cell death (apoptosis). In some cases, proteolysis can be used to regulate

Osteocyte (2,520 words) [view diff] exact match in snippet view article find links to article

a consequence of senescence, degeneration/necrosis, apoptosis (programmed cell death), and/or osteoclastic engulfment. The percentage of dead osteocytes

Carlo Gambacorti-Passerini (634 words) [view diff] exact match in snippet view article find links to article

revolutionary drug. Specifically, he showed that apoptosis, or programmed cell death, was the predominant mechanism through which imatinib eliminates

Annexin A5 affinity assay (853 words) [view diff] exact match in snippet view article find links to article

only on the inner leaflet of the membrane. Apoptosis is a form of programmed cell death that is used by the body to remove unwanted, damaged, or senescent

FOXO3 (2,309 words) [view diff] exact match in snippet view article find links to article

apoptotic process positive regulation of hydrogen peroxide-mediated programmed cell death response to dexamethasone cellular response to nerve growth factor

Animal testing on invertebrates (899 words) [view diff] exact match in snippet view article find links to article

programmed to die during development, leading to the discovery that programmed cell death is an active process under genetic control. The simple nervous system

PLCG2 (1,405 words) [view diff] exact match in snippet view article find links to article

phosphatidylinositol biosynthetic process negative regulation of programmed cell death B cell differentiation T cell receptor signaling pathway activation

Dz13 (1,060 words) [view diff] case mismatch in snippet view article find links to article

Cytotoxicity in Endothelial Cells with Features of Nonapoptotic Programmed Cell Death. Oligonucleotides 18(3), 257-268. Fahmy, R. et al (2006) Suppression

6-Diazo-5-oxo-L-norleucine (987 words) [view diff] exact match in snippet view article find links to article

could be shown in vitro that DON treatment led to apoptosis, the programmed cell death. Different pathways were investigated. So it could be shown that

Bortezomib (2,176 words) [view diff] exact match in snippet view article find links to article

prevent degradation of pro-apoptotic factors, thereby triggering programmed cell death in neoplastic cells. Bortezomib causes a rapid and dramatic change

Breast cancer (14,899 words) [view diff] exact match in snippet view article find links to article

and to die at the proper time. Normal cells will self-destruct (programmed cell death) when they are no longer needed. Until then, cells are protected

POU4F1 (2,159 words) [view diff] exact match in snippet view article find links to article

regulation of transcription by RNA polymerase II negative regulation of programmed cell death positive regulation of osteoclast differentiation regulation of

Death-associated protein 6 (1,528 words) [view diff] exact match in snippet view article find links to article

death. It is also essential for development of nerval system by programmed cell death. The real apoptotic process starts after activating this pathway

Lipid signaling (5,635 words) [view diff] exact match in snippet view article find links to article

mediates many cell-stress responses, including the regulation of programmed cell death (apoptosis) and cell aging (senescence). Numerous research works

Nucleoside-modified messenger RNA (2,503 words) [view diff] exact match in snippet view article find links to article

interferon and TNF-alpha, and when sufficiently intense lead to programmed cell death. The inflammatory nature of exogenous RNA can be masked by modifying

T helper cell (6,597 words) [view diff] exact match in snippet view article find links to article

inflammasomes, thus causing pyroptosis (a highly inflammatory form of programmed cell death). At this point chronic inflammation ensues, and functional CD4+

Christopher E. Rudd (898 words) [view diff] exact match in snippet view article find links to article

synthase kinase-3 (GSK-3) to down-regulate the inhibitory co-receptor programmed cell death-1 (PD-1) in cancer immunotherapy. Rudd's work has had important

Taurolidine (2,202 words) [view diff] exact match in snippet view article find links to article

Brock M, Möhler H (2003-06-01). "Enhancement of Fas-ligand-mediated programmed cell death by taurolidine". Anticancer Research. 23 (3B): 2309–14. PMID 12894508

Addiction module (701 words) [view diff] exact match in snippet view article find links to article

Engelberg-Kulka, Hanna; Gad Glaser (October 1999). "Addiction modules and programmed cell death and antideath in bacterial cultures". Annual Review of Microbiology

DCPS (gene) (1,046 words) [view diff] exact match in snippet view article

process mRNA cis splicing, via spliceosome negative regulation of programmed cell death mRNA processing nuclear-transcribed mRNA catabolic process,

DFNA5 (922 words) [view diff] exact match in snippet view article find links to article

signaling pathway negative regulation of cell population proliferation programmed cell death cell death positive regulation of MAPK cascade necrotic cell death

Biological life cycle (2,968 words) [view diff] exact match in snippet view article find links to article

cell damage, terminal differentiation as occurs in nerve cells, or programmed cell death (apoptosis) during development. Maintenance of cell division potential

Rakesh Bhatnagar (353 words) [view diff] case mismatch in snippet view article find links to article

Biology of Infectious Diseases, Recombinant Vaccine Development, and Programmed Cell Death in Prokaryotes. Kumar, Mamidala Jagadesh (1 August 2016). "Prof

T cell (9,026 words) [view diff] exact match in snippet view article find links to article

exhausted the cells that present the same molecular markers (typically, programmed cell death protein 1 [PD-1])." Dysfunctional T cells are characterized by progressive

Ciliary neurotrophic factor (1,740 words) [view diff] exact match in snippet view article find links to article

organ morphogenesis neuron development regulation of retinal cell programmed cell death nervous system development ciliary neurotrophic factor-mediated

Serine/threonine-specific protein kinase (1,202 words) [view diff] exact match in snippet view article find links to article

Serine/threonine kinases play a role in the regulation of cell proliferation, programmed cell death (apoptosis), cell differentiation, and embryonic development. While

Neurotoxicity (2,249 words) [view diff] exact match in snippet view article find links to article

3,4-Dihydroxyphenylacetaldehyde (DOPAL), is a potent inducer of programmed cell death (apoptosis) in dopaminergic neurons. DOPAL may play an important

Venetoclax (2,389 words) [view diff] exact match in snippet view article find links to article

the anti-apoptotic B-cell lymphoma-2 (Bcl-2) protein, leading to programmed cell death of CLL cells. Overexpression of Bcl-2 in some lymphoid malignancies

Myristoylation (2,277 words) [view diff] exact match in snippet view article find links to article

its receptor. Myristoylation is an integral part of apoptosis, or programmed cell death. Apoptosis is necessary for cell homeostasis and occurs when cells

Antinuclear antibody (6,092 words) [view diff] exact match in snippet view article find links to article

lymphocytes that recognise human proteins (autoantigens) either undergo programmed cell death (apoptosis) or become non-functional. This self-tolerance means

Lung cancer (9,708 words) [view diff] exact match in snippet view article find links to article

affect the cell's normal functions, including cell proliferation, programmed cell death (apoptosis), and DNA repair. Eventually, cells gain enough genetic

DLC1 (3,165 words) [view diff] exact match in snippet view article find links to article

phosphorylation is as yet unknown. DLC1 is responsible for inducing programmed cell death by at least two mechanisms: caspase-3-mediated apoptosis and Bcl-2

AV-HALT (793 words) [view diff] exact match in snippet view article find links to article

Capron, A (1991). "Cell dysfunction and depletion in AIDS: The programmed cell death hypothesis". Immunology Today. 12 (4): 102–5. doi:10.1016/0167-5699(91)90092-8

BAG1 (1,637 words) [view diff] exact match in snippet view article find links to article

protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred

Chromosome 15 (3,031 words) [view diff] exact match in snippet view article find links to article

albinism II (pink-eye dilution homolog, mouse) PDCD7: encoding protein Programmed cell death protein 7 PIF1: encoding protein PIF1 5'-to-3' DNA helicase PIGBOS1:

Thirumala-Devi Kanneganti (4,323 words) [view diff] exact match in snippet view article find links to article

inflammasome/pyroptotic pathway is closely connected to the caspase-8–mediated programmed cell death pathway. This finding went against the dogma that existed at that

Aortic aneurysm (3,149 words) [view diff] exact match in snippet view article find links to article

short, raising HDL cholesterol is beneficial because it induces programmed cell death. The walls of a failing aorta are replaced and strengthened. New

RIPK1 (4,148 words) [view diff] exact match in snippet view article find links to article

of extrinsic apoptotic signaling pathway positive regulation of programmed cell death tumor necrosis factor-mediated signaling pathway positive regulation

Josef Victor Rohon (408 words) [view diff] exact match in snippet view article find links to article

2004). "Slow degeneration of zebrafish Rohon-Beard neurons during programmed cell death". Developmental Dynamics. 229 (1): 30–41. doi:10.1002/dvdy.10488

DNAJA3 (1,956 words) [view diff] exact match in snippet view article find links to article

positive regulation of apoptotic process negative regulation of programmed cell death regulation of catalytic activity negative regulation of NF-kappaB

Anteater (4,538 words) [view diff] exact match in snippet view article find links to article

adaptations that lead to very low rates of cancer among them, such as programmed cell death at very low levels of DNA damage. The silky anteater and both of

PDX1 (2,449 words) [view diff] exact match in snippet view article find links to article

be important in mediating the effect of insulin on the apoptotic programmed cell death of β-cells: a small concentration of insulin protects β-cells from

EIF4A1 (2,579 words) [view diff] exact match in snippet view article find links to article

3109/10409238.2014.887051. PMID 24520918. S2CID 207506515. "PDCD4 programmed cell death 4 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Ali

N. Louise Glass (666 words) [view diff] exact match in snippet view article find links to article

and molecular analyses of mating type, nonself recognition and programmed cell death in filamentous fungi. In 1999 she was recruited to the Plant and

MAGED1 (1,202 words) [view diff] exact match in snippet view article find links to article

demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms

The Extra Lens (360 words) [view diff] case mismatch in snippet view article find links to article

"Cruiserweights", "Only Existing Footage", "Communicating Doors", "Programmed Cell Death", "How I Left the Ministry", "Some Other Way", "Ambivalent Landscape

Anti-neutrophil cytoplasmic antibody (2,245 words) [view diff] exact match in snippet view article find links to article

hypersensitivity reaction.[citation needed] Neutrophil apoptosis, or programmed cell death, is vital in controlling the duration of the early inflammatory

MYND zinc finger (565 words) [view diff] exact match in snippet view article find links to article

Cohen JJ (August 1991). "Identification of mRNAs associated with programmed cell death in immature thymocytes". Mol. Cell. Biol. 11 (8): 4177–88. doi:10

Insulator (genetics) (2,064 words) [view diff] exact match in snippet view article

processes that are important for cell growth, cell differentiation, and programmed cell death (apoptosis). Two of these cell cycle regulation genes that are known

Tumor suppressor gene (3,406 words) [view diff] exact match in snippet view article find links to article

induce apoptosis. If damage cannot be repaired, the cell initiates programmed cell death to remove the threat it poses to the organism as a whole. (e.g.

PAWR (1,352 words) [view diff] exact match in snippet view article find links to article

proliferation positive regulation of hydrogen peroxide-mediated programmed cell death positive regulation of apoptotic process Sources:Amigo / QuickGO

Paraplegin (1,256 words) [view diff] exact match in snippet view article find links to article

permeability mitochondrial outer membrane permeabilization involved in programmed cell death mitochondrion organization anterograde axonal transport Sources:Amigo

Fox Chase Cancer Center (2,152 words) [view diff] exact match in snippet view article find links to article

and AKT2 genes - the first viral oncogenes described that inhibit programmed cell death. 1991 Timothy Yen discovers that a molecular motor controls the

Germ cell (4,039 words) [view diff] exact match in snippet view article find links to article

is also ensured by a balance between germ cell development and programmed cell death. Identification of «death triggering signals» and corresponding

Lina M. Obeid (863 words) [view diff] case mismatch in snippet view article find links to article

Linardic, Corinne M.; Karolak, Linda A.; Hannun, Yusuf A. (1993). "Programmed Cell Death Induced by Ceramide". Science. 259 (5102): 1769–1771. Bibcode:1993Sci

John Angus Hickman (924 words) [view diff] exact match in snippet view article find links to article

"Drug-target interactions: only the first step in the commitment to a programmed cell death?". Br. J. Cancer. 64 (1): 192–196. doi:10.1038/bjc.1991.269. PMC 1977304

STK24 (1,375 words) [view diff] exact match in snippet view article find links to article

regulation of multiple functions of the cells and interaction with programmed cell death 10 (CCM3). CCM is a pathological vascular situation that, influencing

Cell cycle withdrawal (2,194 words) [view diff] exact match in snippet view article find links to article

cells to stop their functions and differentiations to undergo a programmed cell death process called apoptosis. Furthermore, the withdrawal process could

2002 in England (2,416 words) [view diff] exact match in snippet view article find links to article

discoveries concerning 'genetic regulation of organ development and programmed cell death'". Cherie Blair apologises for the embarrassment she caused in buying

Hepatocyte growth factor (2,711 words) [view diff] exact match in snippet view article find links to article

apoptotic process negative regulation of hydrogen peroxide-mediated programmed cell death positive regulation of neuron projection regeneration positive regulation

TMBIM4 (1,028 words) [view diff] exact match in snippet view article find links to article

protein present in the Golgi that helps regulate apoptosis, a form of programmed cell death. By regulating the fluxes of Ca+2, an increase of GAAP can help

B-cell prolymphocytic leukemia (2,386 words) [view diff] no match in snippet view article find links to article

checkpoint of the cell cycle as well as certain genes responsible for programmed-cell death (apoptosis). It is believed that mutations to TP53 are responsible

Nuclear pore glycoprotein p62 (2,260 words) [view diff] exact match in snippet view article find links to article

kinase/NF-kappaB signaling protein transport negative regulation of programmed cell death nuclear transport viral process positive regulation of epidermal

Uncombable hair syndrome (2,545 words) [view diff] exact match in snippet view article find links to article

induces cell proliferation, migration, and invasion, and promotes programmed cell death. This came to show that Transglutaminse 3 will be a candidate growth

Geoffrey M. Cooper (644 words) [view diff] exact match in snippet view article find links to article

Erhardt, P., Schremser, E.J., and Cooper, G.M. 1999. B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating

RIPK3 (952 words) [view diff] exact match in snippet view article find links to article

regulation of intrinsic apoptotic signaling pathway signal transduction programmed cell death positive regulation of necrotic cell death positive regulation of

HSPA1L (2,317 words) [view diff] exact match in snippet view article find links to article

processes. It plays an important role during embryonal development as programmed cell death and accompanies a variety of normal involutional processes in which

Senolytic (1,986 words) [view diff] exact match in snippet view article find links to article

cytosol where it would activate caspases, leading to apoptosis (programmed cell death). Instead, retention of p53 in the nucleus by FOXO4 promotes cellular

Interleukin 1-alpha (2,691 words) [view diff] exact match in snippet view article find links to article

apoptotic signaling pathway in absence of ligand ectopic germ cell programmed cell death positive regulation of vascular endothelial growth factor production

Ureteral cancer (1,708 words) [view diff] exact match in snippet view article find links to article

undergo a DNA mutation resulting in abnormal growth of cells without programmed cell death; this eventually leads to blockage of the ureter and possibly other

Biogerontology (2,894 words) [view diff] exact match in snippet view article find links to article

genes. According to this theory, genes dictate cellular longevity. Programmed cell death, or apoptosis, is determined by a "biological clock" via genetic