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alternate case: wild type

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indicators can include enlargement of the tongue and periorbital purpura. In wild-type ATTR amyloidosis, non-cardiac symptoms include: bilateral carpal tunnel

(FDA) approved cetuximab (Erbitux) for treatment of colon cancer with wild-type KRAS, since it had little or no effect in colorectal tumors harboring

motility) SmR (resistance to the antibiotic streptomycin) In the case of Lac, wild type cells are Lac+ and are able to use lactose as a carbon and energy source

raltegravir, in that "MK-2048 has a dissociation half-life of 32 hours on wild-type integrase—more than four times that of raltegravir", and its dissociation

wild-type males had a significant advantage over GloFish when it came to mating. According to the mating trials that were analyzed in the study, wild-type

DCs exhibit type I IFN responses that are more pronounced than those of wild-type cells in response to viral exposure. As a result, flaviviruses and pseudo

currently working on music for an upcoming album. The band's sixth studio LP, Wild Type Droid, was released on December 3, 2021. On January 12, 2022, Failure

of proteins. For instance, the double‑stranded DNA (dsDNA) genome of wild-type HCMV strains has a size of around 235 kb and encodes at least 208 proteins

functional RMD) and the wild-type rice plant (with a functional RMD). The anther and pistil were shorter in the rmd-1 mutants than the wild-type. This experiment

CAR-T cells protect mice from CRS; however, IL-6 knockout mice receiving wild-type CAR-T cells were not protected from CRS. Moreover, mice infused with GM-CSF

— A subset of gastrointestinal stromal tumors previously regarded as wild-type tumors carries somatic activating mutations in KIT exon 8 (p.D419del)

1996. One month later, the Phillips group independently reported the wild-type GFP structure in Nature Biotechnology. These crystal structures provided

subunits of GABA-A receptors have been identified. A research study compared wild-type to knockout GABRA4 gene in mice. It was determined that the elimination

studies and nuclear magnetic resonance techniques. Using a mutated pseudo-wild-type protein specifically mutated to prevent precipitation at high pH, the

three substrates are Prostaglandin D2, NADPH, and H+. PGFS is a monomeric wild-type protein that was first purified from bovine lung (PDB ID: 2F38). This

Lane, DP; Fersht, AR (23 December 1997). "Thermodynamic stability of wild-type and mutant p53 core domain". Proc. Natl. Acad. Sci. U.S.A. 94 (26): 14338–42

~60% of random sequences can evolve expression levels comparable to the wild-type lac promoter with only one mutation, and that ~10% of random sequences

variability of wild-type lines among institutions may contribute to the replication crisis in biomedical research. Genetic differences in wild-type lines among

wild-type p53 in a dominant negative manner. Mutated p53 proteins are typically more stable than wild-type, and can inhibit the activity of the wild-type

virus, but has a very different timing and course. SSPE is caused by the wild-type virus, not by vaccine strains. SSPE is characterized by a history of primary

for mutant channels versus wild-type. The D188V mutant, for example, recovers to 90% maximal current in 200ms while wild-type channels are unable to recover

these wild-type PAX3-expressing cancers, PAX3 function impacts on the control of proliferation, apoptosis, differentiation and motility. Therefore, wild-type

glioma with wild-type IDH1/2 genes. In WHO grade III glioma, IDH1/2-mutated glioma have a median prognosis of ~3.5 years, whereas IDH1/2 wild-type glioma perform

doubling in weight, to some fish that are almost 100 times heavier than the wild-type at a comparable age. This research area has resulted in dramatic growth

HYDROLYTIC ACTIVITY, II. STRUCTURE OF THE ACTIVE SITE WITH ADP OR ATP BOUND TO WILD TYPE AND MUTANT ATPASE FRAGMENT 1ngb: STRUCTURAL BASIS OF THE 70-KILODALTON

irradiated wild-type mice, and the rate of malignancy within the tumors was higher in the OGG1 knock-out mice (73%) than in the wild-type mice (50%).

Pitrakinra (trade name Aerovant) is a 15-kDa human recombinant protein of wild-type human interleukin-4 (IL-4). It is an IL-4 and IL-13 antagonist that has

administration, tazemetostat selectively inhibits the activity of both wild-type and mutated forms of EZH2. Inhibition of EZH2 specifically prevents the

frequently mutated genes in acute myeloid leukemia (AML). High levels of wild-type FLT3 have been reported for blast cells of some AML patients without FLT3

12.0 pA) than those expressing wild-type channels (124.1 ± 7.4 pA). Furthermore, while DRG neurons expressing wild-type channels only respond with a few

in mCRC patients with KRAS wild-type tumors. In the Phase III CRYSTAL study, published in 2009, patients with the wild-type KRAS gene treated with Erbitux

diarylpyrimidine analogues of TMC278 and their antiviral activity against HIV-1 wild-type and mutant strains". Eur J Med Chem. 42 (5): 567–79. doi:10.1016/j.ejmech

removed the "brittle rachis" problem from wheat. A ripe head ("ear") of wild-type wheat is easily shattered into dispersal units when touched, or blown

hyphae with a woolly colony texture and white mycelia. The green colour of wild-type colonies is due to pigmentation of the spores, while mutations in the

neurons versus wild-type. Consequently, these mutant mice were more susceptible to cortical-spreading-depression than their wild-type counterparts. The

advantage for the males compared to the wild-type; albino males had higher mount frequencies than wild-type males. In addition, the albinos had greater

tumors as Astrocytoma, IDH mutant, grade 4. Only tumors that are IDH wild type are now classified as glioblastoma. There are currently three molecular

Abies seed cone disintegrates is also called the rachis. A ripe head of wild-type wheat is easily shattered into dispersal units when touched or blown by

which are light green in the wild-type, to skyblue and the colour of mask and other parts which are yellow in the wild-type, to white. In the domesticated

to wild type, while homo-mutated genotypes have virtually zero enzyme activity. The ALDH2-deficient subunit is dominant in hybridization with a wild type

knocked-out gene. When these chimera mice are crossbred with others of the wild type, some of their offspring will have one copy of the knocked-out gene in

(10-fold) in T-cell receptor (TCR) diversity compared with that of normal, or wild-type, systems. The greater diversity of TCRs that an organism is equipped with

EGFR-expressing metastatic colorectal cancer in patients with non-mutated (wild-type) KRAS". Panitumumab was the first monoclonal antibody to demonstrate the

streams, coastal brackish, and marine waters from Mexico to Colombia. The wild-type fishes are dull, silvery in color. The molly can produce fertile hybrids

consumption. Transgenic mice that overexpress Klotho live longer than wild-type mice. The α-klotho gene is located on chromosome 13, and is translated

tabby pattern, producing a non-patterned, or agouti tabby (much like the wild type agouti coat of many other mammals and the sable coat of dogs), with virtually

functional domains of wild-type PPAR y Deregulation of PAX8 function Activation of a set of genes unrelated to both wild-type PPARy and wild-type PAX8 pathways

lacks the ability to produce a certain surface protein, usually found on wild-type P. syringae. The "ice-plus" protein (INA protein, "Ice nucleation-active"

and Suffused Whites. The Dilute mutation changes the body colour of the wild-type Light Green to yellow, with a variable amount of light green suffusion

suggests that gene expression can oscillate with the period seen in dividing wild-type cells independently of the CDK machinery. Orlando et al. used microarrays

Transgenic mice expressing the X protein in liver are more likely than the wild type to develop hepatocellular carcinoma. This is because the X protein promotes

present more often in The United States. This type is considered the wild-type mutation which leads to the development of TTR deposits. It usually affects

domesticated Chinese hamsters: normal / wild type dominant spot or spotted white black-eyed white normal / wild-type (note the large scrotum, left) dominant

regulation of mitosis. Wild-type p53 has been shown to repress survivin expression at the mRNA level. Using an adenovirus vector for wild-type p53, human ovarian

strains to identify streptomycin-containing extracts). Paired strains (e.g. wild type and target overexpressing strains) can also be used to identify antibacterial

heterozygous at a gene locus when its cells contain two different alleles (one wild-type allele and one mutant allele) of a gene. The cell or organism is called

MACF1 associate with cables of F-actin, causing cell migration to stall. Wild-type cells with MACF1 present have coordinated cytoskeletal dynamics, which

to wild-type cells. HRR appears to be efficient. In E. coli, even though one or two unrepaired crosslinks are sufficient to inactivate a cell, a wild-type

p53–MDM2 interaction that leads to activation of the p53 pathway in p53 wild-type cells. Inhibiting the interaction between mdm2 and p53 stabilizes p53

analysis of the first Malaysian Genome sequencing and analysis of the Wild-type strain of Zebrafish and the IndiGen programme on Genomics for Public Health

Q248H (mostly heterozygotes) than in wild-type SLC40A1. In xenopus oocytes and HEK 293 cells, the expression of wild type ferroportin was similar to the expression

p53–MDM2 interaction that leads to activation of the p53 pathway in p53 wild-type cells. Inhibiting the interaction between mdm2 and p53 stabilizes p53

have significantly higher level of dopamine in the striatum tissue than wild-type littermates and lower level of norepinephrine in hippocampus. Also, they

mutational traits. Colour varieties in aviculture Wild type Left: Wild type Right: Lutino mutation Left: Wild type Right: Pied Green mutation Aqua Turquoise mutation

JR, O'Brien RW (1969). "Oxidation of d-Malic and β-Alkylmalic Acids by Wild-Type and Mutant Strains of Salmonella typhimurium and by Aerobacter aerogenes"

APLYSIA MYOGLOBIN 1mno: V68N MYOGLOBIN OXY FORM 1mwc: WILD TYPE MYOGLOBIN WITH CO 1mwd: WILD TYPE DEOXY MYOGLOBIN 1myg: HIGH RESOLUTION X-RAY STRUCTURES

compared to wild-type only receptors. These mutant containing receptors also recover from desensitization at a much slower rate than wild-type only receptors

amoeboid, lacking flagella and acrosomes. When self-inseminated, the wild-type worm lays about 300 eggs. When inseminated by a male, the number of progeny

these cells do not mediate comparable levels of cell-cell aggregation to wild-type PTPrho, demonstrating that the mutations observed in cancer are loss of

irinotecan compared to cetuximab and irinotecan in patients with KRAS (exon 2) wild-type metastatic colorectal cancer. Patients included in the study failed treatment

phosphorylated than the wild type Akt1. The ubiquitinated-phosphorylated-Akt1 (E17K) translocates more efficiently to the nucleus than the wild type Akt1. This mechanism

activation molecule (SLAMF1) and the cell adhesion molecule Nectin-4. For wild type and vaccine strains, extracellular domains of CD150 (SLAM or SLAMF1) and/or

Green has green body feathers only very slightly paler than the normal or wild-type Light Green with highly contrasting yellow wings. The Clearwing Skyblue

therapy wherein the liver expressing wild-type and mutant TTR is replaced by a liver only expressing wild-type TTR. Moreover, transplanted patients must

co-culture with the wild type (WT), or chemotherapy-sensitive cells, the resistance to chemotherapy is conferred to the wild type cells, and thus no cell

Tetrahymena species are 45-ploid for their macronucleus, meaning that the wild type of T. thermophila normally contains 45 copies of each chromosome. While

rather delay its initiation. The rate of DNA elongation is not slower than wild-type in such mutant infections. Mutants defective in genes 39, 52 or 60 show

Escherichia coli (E. coli). It was discovered by Esther Lederberg in 1950. The wild type of this virus has a temperate life cycle that allows it to either reside

synthetic S. cerevisiae genome from scratch that is more stable than the wild type. In the synthetic genome all transposons, repetitive elements and many

cells are observed in the L3 and L4 developmental stages when compared to wild-type worms. It is thought that the extra cells arise due to mutant miRNAs being

completely inactive while spectral analysis indicated no major changes from wild-type form. The data is suggestive of direct impairment at a key residue involved

CF: Because the patient is unaffected, she is either homozygous for the wild-type allele, or heterozygous. To establish prior probabilities, a Punnett square

chromatography, then used to separate recombinant, overexpressed protein from wild type protein expressed by the host organism. It can also be used in the isolation

amyloid cardiomyopathy and familial amyloid polyneuropathy, as well as wild-type transthyretin amyloidosis, which formerly was called senile systemic amyloidosis

Wild-type Physcomitrella and knockout mosses: Deviating phenotypes induced in gene-disruption library transformants. Physcomitrella wild-type and transformed

(2006). "Overgrowth caused by misexpression of a microRNA with dispensable wild-type function". Dev Biol. 291 (2): 314–24. doi:10.1016/j.ydbio.2005.11.047

rhythm to that of wild type flies, Konopka and Orr found that light pulses reset the mutant clock to a greater extent than the wild type clock (about 10

Micratya poeyi, Caribbean dwarf filter shrimp Neocaridina davidi (wild type), Wild type cherry shrimp Neocaridina davidi var. red, Cherry shrimp Neocaridina

and Grey standard varieties. The Dominant Grey mutation transforms the wild-type Light Green into the Grey-Green variety and the Skyblue into the Light

signaling, immune responses and regulation of cell proliferation. Compared to wild-type naïve T cells, ICOS-/- T cells activated with plate-bound anti-CD3 have

and *3), expressed as a percentage of the mean dose in patients with wild-type alleles (*1/*1), concluded that the mean warfarin maintenance dose was

aggregation is known to be associated with amyloid diseases including wild-type transthyretin amyloidosis, hereditary transthyretin amyloidosis, familial

than wild-type. These mutations have also been demonstrated to have a dominant-negative effect on wild-type protein trafficking, meaning that wild-type surface

the adjacent gene. This gives an appearance of yellow patches on the wild-type background in Drosophila. another example of mitotic recombination is

signaling accumulate less oxidative damage and live dramatically longer than wild-type flies. In the tiny roundworm Caenorhabditis elegans, loss-of-function

Females with recessive mutation crossed with wild-type males would yield the same phenotype as the wild-type, and any observable change to the phenotype

selected regions. Phylogenetic analysis of VZV genomic sequences resolves wild-type strains into nine genotypes (E1, E2, J, M1, M2, M3, M4, VIII and IX).

interactions in Escherichia coli cells mixedly infected with bacteriophage T4D wild-type and amber mutants and their possible implications as to type of gene-product

result in channels which open at far more hyperpolarized potentials than wild-type. This will result in photoreceptors that continue to release neurotransmitter

Tabtiang R (1993). "A C. elegans mutant that lives twice as long as wild type". Nature. 366 (6454): 461–464. Bibcode:1993Natur.366..461K. doi:10.1038/366461a0

"Current Production and Metal Oxide Reduction by Shewanella oneidensis MR-1 Wild Type and Mutants". Applied and Environmental Microbiology. 73 (21): 7003–7012

PMID 22495024. Koutnikova H, Campuzano V, Koenig M (Sep 1998). "Maturation of wild-type and mutated frataxin by the mitochondrial processing peptidase". Human

respiratory effects of GAL-021 in BK α subunit knockout (Slo1−/−) and wild-type mice". The FASEB Journal. 26 (1 Supplement): 704.30. doi:10.1096/fasebj

fg+ in the wild-type, with the symbol fg for the mutant allele. In its visual effect, the German Fallow mutation is recessive to its wild-type allele, so

mouse genome, male mice will instantly attack other males, whereas their wild-type counterparts take significantly longer to initiate violent behavior. In

R214W mutation takes twofold longer to reach maximal current compared to wild-type channels. Since the time-course of an action potential is shorter than

of the Adh Wild type allele) gave very similar phenotypical alcohol tolerance as the homozygous dominant flies (two copies of the wild type Adh allele)

four-eyed turtle (Sacalia quadriocellata). While formerly considered to be a wild type species believed to be originally from Hainan, it is now known only from

and a human T cell line lacking CD47. Activation of CD47 with TSP-1 in wild-type cells inhibits proliferation and reduces expression of stem cell transcription

synthase from an extremely thermophilic bacterium thermus thermophilus hb8 (wild type, native, form-2 crystal) Identifiers Symbol HEM4 Pfam PF02602 InterPro

William; Olson, Arthur J.; Belew, Richard K. (2007). "Analysis of HIV Wild-Type and Mutant Structures via in Silico Docking against Diverse Ligand Libraries"

determining the effects of androgens on behavior. To examine neurogenesis, wild-type male rats were compared with male rats that had androgen insensitivity

techniques alike. Localization patterns of wild type OA1-GFP and mutated OA1-GFP were compared. The wild type OA1 localized to late endosomal or lysosomal

to their neighbours and to the organism as a whole is altered. In the wild-type wing, all hairs point towards the distal tip. In the developing wing,

enhanced sensitivity to UV-B and bleomycin-induced DNA damage compared to wild-type plants. Cleistocarpous sporophyte of the moss P. patens P. patens plants

though in some cases the truncated proteins may be able to coassemble with wild-type channels in a dominant negative fashion. The most prevalent ACHM3 mutation

light-yellow feathers and orange/red cheek patches. The "normal grey" or "wild type" of a cockatiel's plumage is primarily grey with prominent white flashes

different sites in the pan-2 gene, so that a cross of B5 ´ B3 yields wild-type recombinants at low frequency. An analysis of 939 asci in which the genotypes

have significant impact on intermediary metabolism. The loss of some wild-type metabolic activity is an important, potentially deleterious and therapeutically

the aquarium trade, often in its gold colored variation rather than the wild-type olive green one. Heros efasciatus is one of the few cichlid species that

its wild-type allele, so a bird possessing a single Scottish Fallow allele (the heterozygote, fs+/fs) is identical in appearance to the wild-type light

p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function". Genes Dev. 8 (24): 2939–52. doi:10.1101/gad.8.24.2939.

by comparing the transcriptome of Purkinje-deficient mice with that of wild-type mice. One illustrative example is the Purkinje cell protein 4 (PCP4) in

aeruginosa PA13 (resistant strain): 32 μg/ml Pseudomonas aeruginosa (wild-type, susceptible): 4 - 8 μg/ml "TOKU-E Technical Application Sheet" (PDF)

HYDROLYTIC ACTIVITY, II. STRUCTURE OF THE ACTIVE SITE WITH ADP OR ATP BOUND TO WILD TYPE AND MUTANT ATPASE FRAGMENT 1ngj: STRUCTURAL BASIS OF THE 70-KILODALTON

tuberculosis bacteria that are deficient in this enzyme are less lethal than wild-type bacteria. 3,4-DHSA itself appears to be toxic to the bacteria while the

peafowl, though most visually carry traits of both. In addition to the wild-type "blue" colouration, several hundred variations in colour and pattern are

contribution of MOR activation to tapentadol and morphine induced analgesia. Wild-type mice exhibited an antinociceptive effect ten times that of OPM1 knockouts

inactivated polio vaccine (IPV) replacing OPV in many countries with controlled wild-type polio transmission. Unlike live attenuated vaccines, inactivated vaccines

bending angle +α, due to light irradiation). In Phycomyces blakesleeanus, wild type sporangiophores contain large, easily seen octahedral paracrystalline

apoptosis, based on no accumulation of wild-type p53 detected upon treatment with the betulinic acid, whereas wild-type p53 protein strongly increased after

wild-type antecedents. Males and females of many domestic strains usually have larger body size and are much more lavishly ornamented than their wild-type

with darker barring, somewhat reminiscent of the head and back of the wild-type budgerigar. When disturbed, a ground parrot flies swiftly just above the

the wild-type protein to alanine 1md4: A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein

was no phenotypic difference observed between the knockout mutants, the wild type, or the AtALMT6-GFP mutants, and the exact cause for this is not fully

comparison to wild-type metabolism. By contrast, CYP3A4*1G allele has more potent enzymatic activity compared to CYP3A4*1A (the wild-type allele). Variability

(February 1993). "Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product". Molecular and Cellular Biology. 13 (2): 762–8

domain of the dioxin receptor that is associated with Hsp90 and maintains wild type ligand binding affinity and specificity". The Journal of Biological Chemistry

cells in the stem. pin3 mutants had shorter hypocotyls and roots than the wild-type, and the same phenotype was seen in plants grown with auxin efflux inhibitors

"Characterization of L-homocysteate-induced currents in Purkinje cells from wild-type and NMDA receptor knockout mice". Journal of Neurophysiology. 82 (5):

treatment of autosomal dominant genetic disorders especially in cases where wild-type allele expression is crucial for organism survival such as Huntington

absent in all other analyzed Pseudomonads. The diverse metabolism of wild-type strains of P. putida may be exploited for bioremediation; for example

cofactor in the repair process. The UV dose that reduces a population of wild-type yeast cells to 37% survival is equivalent (assuming a Poisson distribution

Saeki M, Tanaka-Kagawa T, et al. (2003). "Functional characterization of wild-type and variant (T202I and M59I) human UDP-glucuronosyltransferase 1A10".

inhibitor approved by the FDA was saquinavir, which was designed to target wild-type HIV-1 protease. However, this inhibitor is no longer effective due to

R396H are at the entrance to the active site and have lower Vmax than the wild-type ASL, but the mutants K246E and L311V which are away from the active site

being a valuable research tool in making hydrogen. The C. reinhardtii wild-type laboratory strain c137 (mt+) originates from an isolate collected near

cardiomyopathy (ATTR-CM) results from the aggregation and deposition of mutant and wild-type transthyretin (TTR) protein in the heart. TTR is usually circulated as

human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this

13mV hyperpolarized compared to wild-type. Deactivation of these channels is also slowed drastically compared to wild-type. This results in neurons with

Wild-type Physcomitrella and knockout mosses: Deviating phenotypes induced in gene-disruption library transformants. Physcomitrella wild-type and transformed

duration of a run is usually random in the same sense. An example is wild-type E. coli in a dilute aqueous medium, for which the run duration is exponentially

JH, McCammon JA (April 2004). "HIV-1 protease molecular dynamics of a wild-type and of the V82F/I84V mutant: possible contributions to drug resistance

non-lethal mutants that have a non-wild type phenotype exhibit some activity, but significantly less than wild type. In C. elegans, several mutations in

(one wild-type FANCB allele and one mutant FANCB allele) there is strong selection through X-inactivation for expression of only the wild-type allele

knockout cells with wild-type cells yield spores, "born" from the fruiting bodies, which are 82% wild-type (WT). This is because the wild-type cells are better

stability, another double mutant displayed an increase in comparison to the wild type. Moreover, the β1-β2 connecting loop of the enzyme may also be a future

Bubalus bubalis (water buffalo). The tyrosinase mRNA sequence of the wild-type B. bubalis is 1,958 base pairs (bp) with an open reading frame (ORF) of

redesign, most of the residues in the sequence are maintained as their wild-type amino-acid while a few are allowed to mutate. In de novo design, the entire

dominant relationship to its wild-type allele. That is, there are three distinct phenotypes, possessing zero (the wild type), one (the single factor heterozygote)

Mating in water; the large drake entirely submerges the smaller hen Black wild type Muscovy duck in Baton Rouge Domestic ducklings after 25 days, left perhaps

et al. (1996). "Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant

Both alleles contain a mutation. These three scenarios are known as "Wild–type", "Heterozygote" or "Homozygote" respectively. Each gives a melt curve

Lantana Wild-type Spanish flag (Lantana camara) Scientific classification Kingdom: Plantae Clade: Tracheophytes Clade: Angiosperms Clade: Eudicots Clade:

The ABL1 tyrosine kinase activity of BCR-ABL1 is elevated relative to wild-type ABL1. Since ABL activates a number of cell cycle-controlling proteins

Gaillard proposed banning sun-bathing in Marion Square ("This 'Girls-Gone-Wild'-type attitude has caught ahold all across the country. We don't want it to

into the cellular transcription and translation machinery producing a wild type protein or an anti-drug (Fig. 1B). Otherwise, a rejected input will assemble

causes of FASPS is strengthened by the lack of the FASPS phenotype in wild type individuals and by the observed change in the circadian phenotype of these

controls the coding for agouti signaling protein (ASIP; Q865F0). The wild-type dominant A causes the banding and thus an overall lightening effect on

consideration as deglyco-bleomycin has been found to be 100 times less toxic than wild-type BLM. Other forms of BLM forming complexes with various metals has suggested

The normal grey cockatiel, wild type cockatiel, wild cockatiel or grey cockatiel, or Common Cockatiel, is the origin cockatiel of all colour genetics

several lineages have lost their primitive characteristics (such as the wild type colour, long legs and athletic body shape) some lineages still bear considerable

ADRB1-A187V mutated protein leads to a lower cAMP production than the wild-type protein, given the same isoproterenol treatment, a nonselective agonist

antimorphic allele at the Clock locus that codes for an antagonist to the wild-type protein. The presence of an antimorphic protein downregulates the transcriptional

"Isocitrate dehydrogenase kinase/phosphatase. Kinetic characteristics of the wild-type and two mutant proteins". J. Biol. Chem. 271 (32): 19124–8. doi:10.1074/jbc

cadaverine. TAAR6 mutant mice have differences in behavior compared with wild-type mice. Also, they have elevated brain serotonin levels in several brain

Izard J, Sasaki H, Kent R (2012). "Pathogenicity of Treponema denticola Wild-Type and Mutant Strain Tested by an Active Mode of Periodontal Infection Using

subspecies, Ullucus tuberosus subsp. aborigineus, which is considered a wild type. While the domesticated varieties are generally erect and have a diploid

Aasen T, McElwaine S, Kelsell DP (2007). "Tissue-specific effects of wild-type and mutant connexin 31: a role in neurite outgrowth". Hum. Mol. Genet

has occurred; this is a newly discovered mutation. The normal grey or wild-type cockatiel is one whose colour genes have no mutations. A normal grey cockatiel's

deacetylase adaptor protein function, forms Lewy bodies (the regular wild-type protein localized to inclusion bodies). No mutation associated with disease

lifespan by 20% in one study, and by as much as 37% in another study. In wild-type budding yeast Saccharomyces cerevisiae nuclear DNA fragmentation increased

elements arose in the western Aegean before 4000 BCE, based on emmer and wild-type barley, sheep and goats, pigs, and tuna that were apparently speared from

commonly resembles the wild form of angelfish, and is also referred to as "wild-type". It is not, however, caught in the wild and is considered domestic. The

adult virgin female mice are indistinguishable from those of age-matched wild-type virgin female mice. This is in contrast to ERα knockout mice, in which

that produces a mirror scale phenotype is "ssnn" (all recessive), while wild-type carp may have either SSnn or Ssnn genotype.: 13–14  The "S" locus has

necessary for maintaining Ca2+ homeostasis in cells. This means that two wild type copies of ATP2A2 are needed for proper cell function, which provides a

longer herbivory continued the higher the accumulation of jasmonic acid in wild-type plants and in silenced plants, the production of more defence metabolites

Human gamma-B crystallin, wild-type (PDB: 2JDF​). The beta strands making up the beta sheets are coloured blue.

receptors on their cell surfaces due to dimerization between mutant and wild-type receptors that interferes with transport of CCR5 to the cell surface.

one or two unrepaired crosslinks are sufficient to inactivate a cell, a wild-type bacterial cell can repair and therefore recover from 53 to 71 psoralen

"Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels". The Journal of General Physiology. 111 (2): 313–42

example, commonly used laundry detergents may contain subtilisin, whose wild-type form has a methionine that can be oxidized by bleach, significantly reducing

kinked and otherwise malformed tails. They also weigh less than their wild-type littermates but have otherwise a normal life span. Additionally, Ts mice

humans suffering from trichotillomania (TTM). Transplantation of normal (wild-type) bone marrow into a Hoxb8 mutant mouse results in a reduction of compulsive

Postsynaptic density Ultra-structural analysis of synapses in the brainstem of wild-type (WT)mice at embryonic day 18.5. Synapses of WT neurons in the pre-Bötzinger-complex

of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction

the response to exercise training of several proteins and enzymes in wild type and AMPKα2 knockout mice. And even though the knockout mice had lower

[citation needed] Thus results in channels with 30% greater current than wild-type. As this subunit is expressed in the cerebellum, it is assumed that such

(PDF). Time. Retrieved 2023-12-27. Chatters, James C. (2014). "Chapter 4: Wild-Type Colonizers and High Levels of Violence among Paleoamericans". In Allen

and PorB are found in the marine bacteria Zobellia galactinovirans. A wild-type porphyranase activity has been found in Pseudoalteromonas atlantica. BpGH16B

(October 1976). "DNA elongation rates and growing point distributions of wild-type phage T4 and a DNA-delay amber mutant". Journal of Molecular Biology.

" which means "specifically targeting the ABL myristoyl pocket." The wild-type ABL has a myristoylated N-terminus, which binds to an allosteric site

of the N-terminal His tag interferes with the crystallization of the wild-type and mutant SH3 domains from chicken src tyrosine kinase". Acta Crystallographica

of the N-terminal His tag interferes with the crystallization of the wild-type and mutant SH3 domains from chicken src tyrosine kinase". Acta Crystallographica

colour analysis of Persenche is 73% ultramarine, 9% red and 18% white. Wild-type Hyacinthus orientalis in cultivation Pink cultivar Hyacinth cultivars

PROTEIN 1mg4: STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: WILD TYPE PROTEIN 1uf0: Solution structure of the N-terminal DCX domain of human

nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not beta2- or alpha7-nicotinic acetylcholine receptor subunit knockout

D, Primakoff P, Myles DG (June 2000). "Analysis of mouse fertilin in wild-type and fertilin beta(-/-) sperm: evidence for C-terminal modification, alpha/beta

which may be the wild type butyrylcholinesterase, or the mutant. Thus, there may be individuals who are homozygous for the wild type butyrylcholinesterase

irinotecan versus cetuximab plus irinotecan alone for patients with KRAS wild-type metastatic colorectal cancer: the randomised phase I/II POSEIDON trial"

Movement of wild-type C. elegans

character (*) followed by a number. The most common variant (also called wild type) has "CYP2C19*1" label. The variant genotypes of CYP2C19*2 (NM_000769

Cocchi F, Menotti L, Dubreuil P, et al. (2000). "Cell-to-Cell Spread of Wild-Type Herpes Simplex Virus Type 1, but Not of Syncytial Strains, Is Mediated

mice, podocyte foot processes were also more sparse and disperse than in wild-type mice. Chloride channel GRCh38: Ensembl release 89: ENSG00000112782 – Ensembl

transferred to wild type germ-free mice by microbiome transplant from PGLYRP2-deficient mice. PGLYRP2-deficient mice are more susceptible than wild type mice to

Nathanson NM (Nov 1994). "Regulation of cAMP-mediated gene transcription by wild type and mutated G-protein alpha subunits. Inhibition of adenylyl cyclase activity

grouse (right) Mulards, hybrids between a domestic Muscovy duck and a wild-type mallard Haldane's rule Polyploidy Punctuated equilibrium Speciation Species

031. PMID 17241872. Du X, Jensen P, Goldowitz D, Hamre KM (May 2007). "Wild-type cells rescue genotypically Math1-null hair cells in the inner ears of

a much more severe case of cystic fibrosis than individuals with the wild-type gene. Individuals with chronic obstructive pulmonary disorder were impacted

Cypriniformes Temporal range: Paleocene–recent PreꞒ Ꞓ O S D C P T J K Pg N A wild-type common carp (Cyprinus carpio, Cyprinidae: Cyprininae) Scientific classification

natural killer cell receptor dimer has higher affinity for HLA-C than wild-type monomer". Eur. J. Immunol. 30 (9): 2692–7. doi:10

that will support the activation of MMP-2 is cell-cell clustering. A wild-type activated leukocyte cell adhesion molecule (ALCAM) is also required to

cofactor three times faster than the wild-type protein. 5-Methyl-THF slows the rate of FAD release in both the wild-type and mutant enzymes, although it is

brood care in comparison to wild-type specimens. Electric Blue "Goldface" morph "German Gold" morph Xanthic morph Wild-type (Colombian) Wikimedia Commons

70% of wild-type, Ser113Leu reduced enzyme activity to 34% of wild-type, and several severe mutations reduced activity to 5-10% of wild-type. However

provides a selective advantage for gain of whole chromosome 7 in IDH wild-type glioblastoma". Genes & Development. 32 (7–8): 512–523. doi:10.1101/gad

also highly susceptible to damage from prolonged desiccation, while the wild-type strain is resistant to both. It was also shown that desiccation induces

helps distinguish between wild-type and mutant DNA fragments, as one fluorescent probe binds specifically to the wild-type DNA and the other to specific

test, and reduced cerebrospinal fluid myo-inositol content, compared to wild-type littermates. Mega-dosing of myo-inositol reverses all these phenotypes

the binding affinities and forms for NPN bound in wild-type MUP and the Y120F MUP mutant. In wild-type MUP there is just enough room for the amine group

BJ, Ihrke G, et al. (2002). "Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes". Mol. Biol. Cell. 13 (3): 1071–82. doi:10

(Oct 1994). "Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells". Nature Genetics. 8 (2): 171–6.

Patel YC, Srikant CB (December 1996). "Subtype-selective induction of wild-type p53 and apoptosis, but not cell cycle arrest, by human somatostatin receptor

III clinical trials as a potent heterotopic ossification inhibitor in wild-type and ACVR1 mutant mice. International FOP Association Osteogenesis imperfecta –

800 people were affected, with 200 children hospitalized. Cavatak, a wild-type Coxsackievirus A21, is being used in human clinical trials as an oncolytic

distinguished in the marketplace. These are quite similar to common "wild type" Mercenaria clams, except that their shells bear distinctive markings

influence; a distinctive group of domesticated animals differentiated from the wild type under the influence of man, the sum of the progeny of a known and designated

cerevisiae and result in a dramatic reduction in post-diauxic lifespan. In wild-type S. cerevisiae, DNA damage rates increased 3-fold with age, but more than

shows a higher Km for NAD+ and has a higher maximum velocity than the wild-type allele. This mutation is common in Japan, where 41% of a non-alcoholic

Murakami, R. A histological study of the development of the penis of wild-type and androgen-insensitive mice. J. Anat. 153, 223–231 (1987) Hogan, Lindsay

hobby as the 'Hamburg hybrid Endler strain'. The original japan blue wild type guppy was a Poecilia reticulata collected from Lac du Rorata. Lac du Rorota

Kowlessur D, Citron BA, Kaufman S (December 1995). "Characterization of the wild-type form of 4a-carbinolamine dehydratase and two naturally occurring mutants

of sharp wave ripples which are implicated in memory function in adult wild type rats. The increase in ripple amplitude is not seen in adult male TgF344-AD

need for caution when doing so. ∗ While an LD50 has been reported for wild type C. elegans individuals, an upper lethal limit has not been established

complementarity while maintaining biochemical competence and orthogonality to the wild type pair. Typically, a "bumped" ligand/inhibitor analog is designed to bind

In a mixture of wild-type and mutant amplified DNA, heteroduplexes are formed in mutant alleles and homoduplexes are formed in wild-type alleles. There

wild type plants, indicating that JAs play an important role in the execution of plant defense. When herbivores are moved around leaves of wild type plants

PMID 27518705. Koutnikova H, Campuzano V, Koenig M (Sep 1998). "Maturation of wild-type and mutated frataxin by the mitochondrial processing peptidase". Human

from Bacteriochlorophyll c , d , e , or f to Bacteriochlorophyll a in Wild-Type and Mutant Cells of the Green Sulfur Bacterium Chlorobaculum limnaeum"

PMID 11230166. Loomis PA, Kelly AE, Zheng L, et al. (2006). "Targeted wild-type and jerker espins reveal a novel, WH2-domain-dependent way to make actin

Klf9 gene, more cells die. Similar cell death was found in vivo when wild-type mice were exposed to oxidative stress agent paraquat intranasally, which

as adenovirus or herpes virus, AAV itself did not cause any disease. Wild-type AAV has attracted considerable interest from gene therapy researchers

recombination at frequencies that are about two-fold higher than that of wild-type phage. It was proposed that a mutational alteration in the phage DNA polymerase

R197Q, and G286E. These are classified as slow acetylators, while the wild-type NAT2 is classified as a fast acetylator. Slow acetylators tend to be associated

base excision repair are sensitive to bile salts. This indicates that wild-type S. enterica uses base excision repair to remove DNA damages caused by

provides the unique ability to directly investigate the mechanism of wild-type HEWL and native substrate. The calculations revealed that the covalent

in a microarray analysis of gene expression profiles of the retinas of wild-type and Otx2 knockout mice. A RT-PCR analysis was used to confirm that Otx2

PMID 16344560. Jackson LN, Li J, Chen LA, et al. (2006). "Overexpression of wild-type PKD2 leads to increased proliferation and invasion of BON endocrine cells"

selenomethionine 1zmu: Catalytic and ubiqutin-associated domains of MARK2/PAR-1: Wild type 1zmv: Catalytic and ubiqutin-associated domains of MARK2/PAR-1: K82R mutant

tumors that harbored the mutation. However, in tumors that expressed wild type BRAF, indole-3-carbinol did not cause any comparable antiproliferative

heterodimers in the manufacturing process. The terminal lysine found in wild-type IgG4 is removed. The antibody is produced in Chinese hamster ovary cells

Laboratory: E. coli K-12, one of two laboratory strains (innocuous) Clifton wild type (!) W3110 DH5α Dam dcm strain HB101 Escherichia coli B, the other of the

poliovirus receptor CD155 is a potential risk factor for vaccine and wild-type paralytic poliomyelitis". J. Med. Virol. 81 (5): 933–6. doi:10.1002/jmv

arose in the western Aegean in the third millennium BC based on emmer and wild-type barley, sheep and goats, pigs, and tuna that were apparently speared from

protect the central nervous system and MNs directly. Experiments with wild type Ang found that it slows MN degeneration in mice that had developed ALS

have increased adipose tissue and decreased muscle tissue compared to wild type. Additionally, the presence of the length polymorphism has also been shown

trp gene, are characterized by a transient response to light, unlike wild-type flies that demonstrate a sustained photoreceptor cell activity in response

from the Cooper strain. The Australian Pied allele is dominant over its wild-type allele, although with less than 100% penetrance. The extent and distribution

in the gene encoding the light chain subunit of the ferritin protein. Wild type ferritin functions as a buffer for iron, sequestering it and controlling

key events in the formation of these brain tumors. Glioblastomas with a wild-type IDH1 gene have a median overall survival of only 1 year, whereas IDH1-mutated

vaccination is much lower than getting shingles after natural infection with wild-type VZV." The risk of shingles is significantly lower among children who have

transcripts of AML1/ETO-fused gene in t(8;21) leukemic cells and expression of wild-type ETO gene in hematopoietic cells". Genes Chromosomes Cancer. 13 (1): 25–33

vector arms which are then joined to the foreign DNA. Selection against wild type cosmid DNA is simply done via size exclusion. Cosmids, therefore, always

BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL". Leukemia. 19 (2): 201–8. doi:10.1038/sj

more potent at the low concentration and had a greater effect than the wild-type resistin at the high concentration. This result suggests that processing

gross morphologic, reproductive or behavioral abnormalities compared with wild-type mice, and histologic examination of multiple organ systems has shown no

Miksch K (2012). "Phytoremediation of explosives (TNT, RDX, HMX) by wild-type and transgenic plants". J. Environ. Manage. 113: 85–92. doi:10.1016/j

in their leaves, with more areoles, branch points and free ends than wild-type Arabidopsis. The function of LHY was initially demonstrated by a group

collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants". Biochem. J. 454 (3): 501–13. doi:10

p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function". Genes & Development. 8 (24): 2939–2952. doi:10.1101/gad

in either of these microRNAs appears to restore circadian rhythms to a wild-type level. Given that miR-279 and miR-996 share a similar seed region (i.e

larger at between 30 and 60 cm (12 and 24 in). The "normal grey" or "wild-type" cockatiel's plumage is primarily grey with prominent white flashes on

For example, a model of mouse hemophilia is corrected by expressing wild-type platelet-factor VIII, the gene that is mutated in human hemophilia. Lentiviral

elevated in wild type but not Ffar2 gene knockout mice; 3) fat tissue weight was significantly higher in Ffar2 gene knockout than wild-type mice; and 4)

sweeter and more aromatic. Florence fennel plants are smaller than the wild type. Several cultivars of Florence fennel are also known by several other

mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae". Biochemistry. 41 (48):

Jones GH (January 2003). "Meiotic cytology and chromosome behaviour in wild-type Arabidopsis thaliana". Journal of Experimental Botany. 54 (380): 1–10

effects of Δ9-tetrahydrocannabinol and methanandamide in CB1 knockout and wild-type mice". The Journal of Pharmacology and Experimental Therapeutics. 309

2.8 Angstrom Resolution 1sq0: Crystal Structure of the Complex of the Wild-type Von Willebrand Factor A1 domain and Glycoprotein Ib alpha at 2.6 Angstrom

larger at between 30 and 60 cm (12 and 24 in). The "normal grey" or "wild-type" cockatiel's plumage is primarily grey with prominent white flashes on

burhodogranariea, and resisted infection against Gram-positive bacteria like wild-type flies. It remains to be seen how in vitro activity relates to in vivo

newborn and adult thymus, indicative of a development T-cell role. In wild type neurons, addition of Sema7A under in vitro conditions promotes elongation

influence; a distinctive group of domesticated animals differentiated from the wild type under the influence of man, the sum of the progeny of a known and designated

-dependent form by a single point mutation, D268S. Mutations in TnaT-D268S, in wild type TnaT and in a serotonin transporter (SERT; 2.A.22.1.1) provided direct

mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae". Biochemistry. 41 (48):

Chesnokov I, Remus D, Botchan M (2001). "Functional analysis of mutant and wild-type Drosophila origin recognition complex". Proc. Natl. Acad. Sci. U.S.A.

cultivation; a number of named species may actually just be variants of original wild-type species that horticulturalists bred to appear unique in cultivation. Molecular

the Role of Leu22 Variants in Methotrexate Resistance: Comparison of Wild-type and Leu22Arg Variant Mouse and Human Dihydrofolate Reductase Ternary Crystal

phosphorylation rate (BGPR) of normal ("wild type") glucokinase and the known mutations. The BGPR for wild type glucokinase is about 28% at a glucose concentration

Hernando R, Castaño JG, Alemany S (Oct 2003). "The COOH-terminal domain of wild-type Cot regulates its stability and kinase specific activity". Molecular and

(Bcl-2-associated X protein) a larger percentage of interneurons survived compared to wild type mice. Together these findings indicate that programmed cell death in the

REC1 and BH related mutants show lower or none activity compared with wild type, which indicate these two domains are crucial for the sgRNA recognition

interactions in Escherichia coli cells mixedly infected with bacteriophage T4D wild-type and amber mutants and their possible implications as to type of gene-product

most enzymes, the wild-type diploid level of enzyme activity occurs where the curve is levelling out, then a heterozygote of the wild-type with a null mutant

their potentially deleterious expression is masked by the corresponding wild-type allele, this masking phenomenon is referred to as complementation (see

Arginine and Histidine at position 128 to Aspartate) and compared to the wild-type ECP, the mutated ECP retains its cytotoxicity but no longer has its ribonuclease

bacteria. The incapability of the endosymbiotic bacteria to reinstate their wild type phenotype via a recombination process is called Muller's ratchet phenomenon

transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants". Journal of Medicinal Chemistry. 47

2018-09-24. Retrieved 2018-11-22. "Wild Type raises $3.5M to reinvent meat for the 21st century". 29 March 2018. "Home". Wild Type. Archived from the original

crossed to wild-type males, all progeny had the poky phenotype. When wild-type females were crossed to poky males, all progeny had the wild-type phenotype

residues in the activation segment of BRAF, which are used to activate the wild type form of the protein. The glutamate residue of the mutant therefore functions

localizes to basolateral membranes of polarized MDCK cells similar to the wild type enzyme, indicating no deleterious effect on subcellular location. The

(July 2012). "SOS induction and mutagenesis by dnaQ missense alleles in wild type cells". Mutation Research. 735 (1–2): 46–50. doi:10.1016/j.mrfmmm.2012

This genetic map was constructed from 121 progeny of a cross between two wild type isolates and involved 134 markers. The markers were mostly PCR-based restriction

bonding with Asp-99. An asparagine substitution for His-48 maintains wild-type activity, as the amide functional group on asparagine can also function

The standard appearance of an isopod species is often referred to as 'Wild Type'. Some isopod morphs are characterized by polygenic traits, such as 'Orange

Since the wild-type HSPB1 gene is also expressed alongside the mutated allele, the diseased cells contain a mixed populations of wild-type and mutant

These mice have greater susceptibility to an asthma-like phenotype than wild-type animals. They are resistant to collagen-induced arthritis. Their body

transcript. Topotecan inhibits topoisomerase I restoring UBE3A levels to wild-type range in cultured mince neurons. Transgenic mice with a fluorescently

Y289L mutation showing comparable GalNAc transferase activity as the wild-type enzyme's Gal transferase activity. Deficiency of GALT causes classic galactosemia

"High-Throughput Video Processing of Heart Rate Responses in Multiple Wild-type Embryonic Zebrafish per Imaging Field". Scientific Reports. 9 (1): 145

endolysin from gene R and the spanin proteins from genes Rz and Rz1. In wild-type lambda, lysis occurs at about 50 min, releasing approximately 100 completed

Kundu R (April 1995). "DNA binding and transcriptional properties of wild-type and mutant forms of the homeodomain protein Msx2". Biochemical and Biophysical

possible with the S (white spotting) gene, with capital S standing for a wild-type copy and lower-case s standing for the mutant. SS (two dominant alleles)

arthropathy that results in having less overall locomotor activity than wild type mice. However, recent research suggests that there might be some redundancy

copy of chromosome 13 are sometimes accompanied by loss of the other wild-type chromosome 13 through mitotic nondisjunction. By this combination of lesions

absence of mutations that affect the REase cleavage specificity. When wild-type and mutants are analysed by digestion with different REases, the gel-electrophoretic

infection with foreign particles have also been identified in Drosophila. Wild-type flies normally fully recover after being anesthetized with carbon dioxide

sensitivity to ionizing radiation compared to heterozygous Ku70+/− or wild-type Ku70+/+ embryonic stem cells. Mutant mice deficient in Ku70 exhibit early

early history of domesticating horses: tail-type hair grew instead of the wild-type short stiff hair still present in the manes of other equids such as donkeys

properties of the beta-adrenergic receptor and adenylate cyclase from wild type and variant S49 lymphoma cells". The Journal of Biological Chemistry.

In situ hybridization of wild type Drosophila embryos at different developmental stages for the RNA from a gene called hunchback.

human D172E and G320V), also could bind BMP-2, but less effectively than wild-type HJV, while G92V (human G99V) could not. In contrast, the membrane-spanning

absence of mutations that affect the REase cleavage specificity. When wild-type and mutants are analysed by digestion with different REases, the gel-electrophoretic

acids, and are often used by microbiologists and geneticists to grow "wild-type" microorganisms. Minimal media can also be used to select for or against

Dandelions secrete latex when the tissues are cut or broken, yet in the wild type, the latex content is low and varies greatly. Taraxacum kok-saghyz, the

overexpress AKT increase the amount of CREB and proliferation compared to wild type cells. These cells also express less glial and neural cell markers such

teasing process is called teased wool. The cultivar differs from the wild type in having stouter, somewhat recurved spines on the seed heads. The dried

In addition, CoA levels decrease significantly between PanK1-/- and wild-type mice. This reduction in CoA also appears to correlate with a disruption

One way to do this is to replace the wild-type gene with a 'fusion' gene, which is a juxtaposition of the wild-type gene with a reporting element such as

cultivar 'Rubra' cultivar, showing "eyelashes" 'Nigra Magra' cultivar Wild-type at the Dresden Botanical Garden Flowers of putative variety roseflora

have suggested that both species may have been derived from the same wild type. A weedy quinoa, Ch. quinoa var. melanospermum, is known from South America

antagonism of AGTR2 signaling improved lung function in CF mice to near wild-type levels. Manipulation of the angiotensin-signaling pathway to reduce AGTR2

plasmid and a helper phage so that the resultant phage contains both wild type and fusion pIII. cDNA has also been analyzed using pIII via a two complementary

red seeds. Cultivars of this popular garden plant may vary from these wild-type characteristics; the cultivar 'Lutea' has all-yellow tepals, 'Citrina'

junglefowl and the green junglefowl in Indonesia is known as the bekisar. Wild-type red junglefowl are thought to be facing threats due to hybridisation at

higher content of polyhydroxybutyrate (PBH) storage granules than the wild type strain. The sRNA is required to limit the PBH intracellular accumulation

mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae". Biochemistry. 41 (48):

subunits, more glucose transporter (GLUT4) and more fibronectin than wild type controls. Five cyclic peptides show inhibitory activity towards human

they are identical. The Dominant Clearbody allele is dominant over its wild-type allele, so a bird possessing a single Dominant Clearbody allele (the heterozygote

intrinsic terminator hairpins were found inside the epsF coding region. A wild-type EAR element is capable of promoting transcriptional readthrough of these

SJ (2004). "Branched swarming patterns on a synthetic medium formed by wild-type Bacillus subtilis strain 3610: detection of different cellular morphologies

the cancer-suppressing gene p53. The expression of CDKN1A and ARF under wild-type cell cycles is temporary, which results from the RUNX3-BRD2 complex replacing

Sánchez-Chapula JA, Navarro-Polanco RA, Sanguinetti MC (2004). "Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels

mutants with fewer acetylcholine receptors may paralyze slower than wild type. It has been studied as a method to stimulate the immune system as part

as well; the Nme1-deficient mice formed greater lung metastases than wild type mice, showing that this gene has suppressing activity. Invasion of cancer

showed about half the reduction in swimming motility compared to the wild-type strain, and swimming motility was completely restored by the trans gene

reduces hydrogen peroxide concentrations at the application site, while the wild type responds with an increase. Grossmann, K. (2010). "Auxin herbicides: current

host compensated DNA synthesis is less accurate than that directed by wild-type phage. A mutant defective in gene 39 also shows increased sensitivity

two to four times more likely to develop melanoma than those with two wild-type (typical unaffected type) copies. MC1R mutations are very common, and

FUNCTION BLOCKING NMC-4 FAB 1sq0: Crystal Structure of the Complex of the Wild-type Von Willebrand Factor A1 domain and Glycoprotein Ib alpha at 2.6 Angstrom

reported to extend mean lifespan by over 50% at 25 °C when compared to the wild type worm (N2) in 1987 by Johnson et al. Development, metabolism, lifespan

(August 2003). "Kinetic and physical characterisation of recombinant wild-type and mutant human protoporphyrinogen oxidases". Biochimica et Biophysica

AQUOMET, BETA DEOXY 1xxt: The T-to-T High Transitions in Human Hemoglobin: wild-type deoxy Hb A (low salt, one test set) 1xy0: T-to-THigh Transitions in Human

using N-acetylglucosamine 6-O-sulfotransferase-1 deficient mice. The wild type mouse showed a significant up regulation of mRNA expressing N-acetylglucosamine

glycoprotein syndrome type 1A: expression and characterisation of wild type and mutant PMM2 in E. coli". European Journal of Human Genetics. 7 (8):

anti-EBOV antibodies. The primates were then back-challenged with the wild type Ebola virus and survived. This potentially creates a prospect for a future

bile acids. When the bile acid DCA was added to the standard diet of wild-type mice invasive colon cancer was induced in 56% of the mice after 8 to 10

FUNCTION BLOCKING NMC-4 FAB 1sq0: Crystal Structure of the Complex of the Wild-type Von Willebrand Factor A1 domain and Glycoprotein Ib alpha at 2.6 Angstrom

response to bacterial infection, and higher production of IL-12 than in the wild type. CD83 seems to be an important regulator of dendritic cell phenotype and

spicerianum and druryi and numerous others hybrids been in trade making the wild type difficult to identify in cultivation. After the species was described

5'-TAATTG-3', 5'-TAGTTG-3', and 5'-TAATTA-3'. Knockout study of NOBOX against wild-type ovaries in newborn female mice revealed that 74% (28/38 genes) were downregulated

structure. They also looked at what happened to development of the limbs in wild type mice, that are mice with no CYP26B1 deficiencies, but which had an excess

anti-EBOV antibodies. The primates were then back-challenged with the wild type Ebola virus and survived. This potentially creates a prospect for a future

point that all sodium channels, including channels produced from the wild-type allele and mutant channels that did inactivate, fail to be release from

40% lower arthritis incidence and 50% less disease severity compared to wild-type (WT) mice. CD201 KO mice also had significantly fewer Th1/Th17 cells in

analysis (GDRDA), the fragments of DNA that differed between the mutant and wild type hamsters. With this information, Takahashi then used positional syntenic

Alzheimer's disease, which is the first time this has been seen in a wild-type rodent. After initial interest into common degus as research subjects

remains canalised as long as the expression level is above 40% of the wild-type expression. Strong robustness up to a limit, with little robustness beyond

efficiently compete with the wild-type virus for critical replication resources inside an infected cell. TIPs thereby deprive wild-type virus of replication material

De Meester, Fabien; Watson, Ronald Ross, eds. (January 23, 2008). Wild-type Food in Health Promotion and Disease Prevention: The Columbus Concept

Eumo, Satinette, Bronze, Ivory, Onyx, Mosaic, Brown, red factor, Green (Wild Type): darkest black and brown melanin shade in yellow ground birds, Yellow

family) was traced to homozygous duplication of a mutant RyR2 gene. Normal (wild type) RyR2 functions primarily in the myocardium (heart muscle). Mice with

Combination of both mutants leads to similar activity compared to the wild type. pmHAS additionally contains an Asp-Gly-Ser sequence that is conserved

the fish to attach itself to smooth surfaces. No barbels are present. Wild type colour varies from pale grey to olive, with darker markings along the

less severe experimental autoimmune encephalo-myelitis (EAE) than the wild type mice. Intronic single nucleotide polymorphism (SNP) mostly in third intron

lateral sclerosis. However, several pieces of evidence also show that wild-type SOD1, under conditions of cellular stress, is implicated in a significant

Thayer, Alan (2005). "A new look at conservation as a means of maintaining wild type genetic variation among economically important crop species". International

transcription is differentially regulated by EWS/ERG sarcoma fusion protein and wild-type ERG". The Journal of Biological Chemistry. 278 (13): 11369–75. doi:10

pyrrolo[2,3-b]pyrazines derivatives as submicromolar affinity activators of wild type, G551D, and F508del cystic fibrosis transmembrane conductance regulator

(August 1990). "Suppression of human colorectal carcinoma cell growth by wild-type p53". Science. 249 (4971): 912–915. Bibcode:1990Sci...249..912B. doi:10

offspring comparable by the number of litters and the number of pups with wild-type mice, and there counterparts, not treated, were completely infertile.

Vertico-SMI/SPDMphymod microscope Fluorescence microscopy of DNA Expression in the Human Wild-Type and P239S Mutant Palladin. Fluorescence microscopy images of sun flares

Distortion of the active site caused by the E285A mutation. Wild type ASPA is on the left (2O4H) and E285A on the right (4NFR).

Ullmann, A.; Jacob, F.; Monod, J. (1968). "On the subunit structure of wild-type versus complemented beta-galactosidase of Escherichia coli". Journal of

to a competitive advantage in Arabidopsis thaliana. Experiments with wild type, short circadian period mutants, and long circadian period mutants demonstrated

p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function". Genes & Development. 8 (24): 2939–52. doi:10.1101/gad.8

disease prions have equivalent transmission properties in transgenic and wild-type mice". Proceedings of the National Academy of Sciences of the United States

mutant RETGC-1 to be activated by GCAP at higher calcium levels than the wild-type. Because RETGC-1 produces cGMP, which keeps cyclic nucleotide-gated channels

arrested by E7.5 of gestation, though could be saved by contribution of wild-type cells to the trophoblast. Expressed in high levels in the extraembryonic

needed] Phenotypic threshold effect is when there is a certain amount of wild-type mtDNA present in the mitochondrion which is able to balance out the number

activity toward MEK is reduced, they adopt a conformation that activates wild-type C-RAF, which then signals to ERK. BRAFV600E mutation confers a poor prognosis

determined and also by comparing the chromatin binding properties of wild-type and HMGN mutant proteins. In conclusion, HMGNs can associate with mitotic

domain of PPAR-delta are viable. However, these mice are smaller than the wild type both neo and postnatally. In addition, fat stores in the gonads of the

Wild-type spermatocyte progression compared to repro4 mutated spermatocytes.

using those autotrophies lies in the fact that they exhibit wild-type or nearly wild-type virulence in a mouse model compared to the URA3 system. One

radiation environment. Two yeast strains were selected for this mission: a wild type strain proficient in DNA repair, and a strain defective in the repair